---
_id: '879'
abstract:
- lang: eng
text: Having an extra copy of a gene is thought to provide some functional redundancy,
which results in a higher rate of evolution in duplicated genes. In this article,
we estimate the impact of gene duplication on the selection of tuf paralogs, and
we find that in the absence of gene conversion, tuf paralogs have evolved significantly
slower than when gene conversion has been a factor in their evolution. Thus, tuf
gene copies evolve under a selective pressure that ensures their functional uniformity,
and gene conversion reduces selection against amino acid substitutions that affect
the function of the encoded protein, EF-Tu.
acknowledgement: We thank Peter Andolfatto, Doris Bachtrog, Robert Cutler, Hideki
Innan, Eugene Koonin, Alexey Kondrashov and Martin Lercher for comments on the manuscript
and for discussions on the interplay between gene conversion and selection. This
work was supported by a National Science Foundation Graduate Research Fellowship
(F.A.K.) and a Molecular and Cellular Biology RAS (Program No 10) grant (P.K.V.).
author:
- first_name: Fyodor
full_name: Fyodor Kondrashov
id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
last_name: Kondrashov
orcid: 0000-0001-8243-4694
- first_name: Tatiana
full_name: Gurbich, Tatiana A
last_name: Gurbich
- first_name: Peter
full_name: Vlasov, Peter K
last_name: Vlasov
citation:
ama: Kondrashov F, Gurbich T, Vlasov P. Selection for functional uniformity of tuf
duplicates in γ-proteobacteria. Trends in Genetics. 2007;23(5):215-218.
doi:10.1016/j.tig.2007.03.002
apa: Kondrashov, F., Gurbich, T., & Vlasov, P. (2007). Selection for functional
uniformity of tuf duplicates in γ-proteobacteria. Trends in Genetics. Elsevier.
https://doi.org/10.1016/j.tig.2007.03.002
chicago: Kondrashov, Fyodor, Tatiana Gurbich, and Peter Vlasov. “Selection for Functional
Uniformity of Tuf Duplicates in γ-Proteobacteria.” Trends in Genetics.
Elsevier, 2007. https://doi.org/10.1016/j.tig.2007.03.002.
ieee: F. Kondrashov, T. Gurbich, and P. Vlasov, “Selection for functional uniformity
of tuf duplicates in γ-proteobacteria,” Trends in Genetics, vol. 23, no.
5. Elsevier, pp. 215–218, 2007.
ista: Kondrashov F, Gurbich T, Vlasov P. 2007. Selection for functional uniformity
of tuf duplicates in γ-proteobacteria. Trends in Genetics. 23(5), 215–218.
mla: Kondrashov, Fyodor, et al. “Selection for Functional Uniformity of Tuf Duplicates
in γ-Proteobacteria.” Trends in Genetics, vol. 23, no. 5, Elsevier, 2007,
pp. 215–18, doi:10.1016/j.tig.2007.03.002.
short: F. Kondrashov, T. Gurbich, P. Vlasov, Trends in Genetics 23 (2007) 215–218.
date_created: 2018-12-11T11:48:59Z
date_published: 2007-05-01T00:00:00Z
date_updated: 2021-01-12T08:21:04Z
day: '01'
doi: 10.1016/j.tig.2007.03.002
extern: 1
intvolume: ' 23'
issue: '5'
month: '05'
page: 215 - 218
publication: Trends in Genetics
publication_status: published
publisher: Elsevier
publist_id: '6771'
quality_controlled: 0
status: public
title: Selection for functional uniformity of tuf duplicates in γ-proteobacteria
type: journal_article
volume: 23
year: '2007'
...
---
_id: '904'
abstract:
- lang: eng
text: 'Background: Independently evolving lineages mostly accumulate different changes,
which leads to their gradual divergence. However, parallel accumulation of identical
changes is also common, especially in traits with only a small number of possible
states. Results: We characterize parallelism in evolution of coding sequences
in three four-species sets of genomes of mammals, Drosophila, and yeasts. Each
such set contains two independent evolutionary paths, which we call paths I and
II. An amino acid replacement which occurred along path I also occurs along path
II with the probability 50-8211;80% of that expected under selective neutrality.
Thus, the per site rate of parallel evolution of proteins is several times higher
than their average rate of evolution, but still lower than the rate of evolution
of neutral sequences. This deficit may be caused by changes in the fitness landscape,
leading to a replacement being possible along path I but not along path II. However,
constant, weak selection assumed by the nearly neutral model of evolution appears
to be a more likely explanation. Then, the average coefficient of selection associated
with an amino acid replacement, in the units of the effective population size,
must exceed ∼0.4, and the fraction of effectively neutral replacements must be
below ∼30%. At a majority of evolvable amino acid sites, only a relatively small
number of different amino acids is permitted. Conclusion: High, but below-neutral,
rates of parallel amino acid replacements suggest that a majority of amino acid
replacements that occur in evolution are subject to weak, but non-trivial, selection,
as predicted by Ohta''s nearly-neutral theory.'
acknowledgement: G.A.B. gratefully acknowledges fellowships from the Pew Charitable
Trusts award 2000-002558 and the Burroughs Wellcome Fund award 1001782, both to
Princeton University. F.A.K. is a National Science Foundation Graduate Fellow. M.B.'s
work is partially supported by the NSERC Discovery grant. I.D. and A.P. were partially
supported by grant HL066681 (L.A.P., I.D. and S.M.), Berkeley-PGA, under the Programs
for Genomic Applications, funded by National Heart, Lung, & Blood Institute and
Department of Energy Contract DE-AC02-05CH11231, University of California. This
work was partially supported through the Molecular and Cellular Biology Program
of the Russian Academy of Sciences.
author:
- first_name: Georgii
full_name: Bazykin, Georgii A
last_name: Bazykin
- first_name: Fyodor
full_name: Fyodor Kondrashov
id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
last_name: Kondrashov
orcid: 0000-0001-8243-4694
- first_name: Michael
full_name: Brudno, Michael
last_name: Brudno
- first_name: Alexander
full_name: Poliakov, Alexander V
last_name: Poliakov
- first_name: Inna
full_name: Dubchak, Inna L
last_name: Dubchak
- first_name: Alexey
full_name: Kondrashov, Alexey S
last_name: Kondrashov
citation:
ama: Bazykin G, Kondrashov F, Brudno M, Poliakov A, Dubchak I, Kondrashov A. Extensive
parallelism in protein evolution. Biology Direct. 2007;2. doi:10.1186/1745-6150-2-20
apa: Bazykin, G., Kondrashov, F., Brudno, M., Poliakov, A., Dubchak, I., & Kondrashov,
A. (2007). Extensive parallelism in protein evolution. Biology Direct.
BioMed Central. https://doi.org/10.1186/1745-6150-2-20
chicago: Bazykin, Georgii, Fyodor Kondrashov, Michael Brudno, Alexander Poliakov,
Inna Dubchak, and Alexey Kondrashov. “Extensive Parallelism in Protein Evolution.”
Biology Direct. BioMed Central, 2007. https://doi.org/10.1186/1745-6150-2-20.
ieee: G. Bazykin, F. Kondrashov, M. Brudno, A. Poliakov, I. Dubchak, and A. Kondrashov,
“Extensive parallelism in protein evolution,” Biology Direct, vol. 2. BioMed
Central, 2007.
ista: Bazykin G, Kondrashov F, Brudno M, Poliakov A, Dubchak I, Kondrashov A. 2007.
Extensive parallelism in protein evolution. Biology Direct. 2.
mla: Bazykin, Georgii, et al. “Extensive Parallelism in Protein Evolution.” Biology
Direct, vol. 2, BioMed Central, 2007, doi:10.1186/1745-6150-2-20.
short: G. Bazykin, F. Kondrashov, M. Brudno, A. Poliakov, I. Dubchak, A. Kondrashov,
Biology Direct 2 (2007).
date_created: 2018-12-11T11:49:07Z
date_published: 2007-08-16T00:00:00Z
date_updated: 2021-01-12T08:21:47Z
day: '16'
doi: 10.1186/1745-6150-2-20
extern: 1
intvolume: ' 2'
month: '08'
publication: Biology Direct
publication_status: published
publisher: BioMed Central
publist_id: '6745'
quality_controlled: 0
status: public
title: Extensive parallelism in protein evolution
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
volume: 2
year: '2007'
...
---
_id: '9149'
abstract:
- lang: eng
text: "The interaction of tidal currents with sea-floor topography results in the
radiation of internal gravity waves into the ocean interior. These waves are called
internal tides and their dissipation due to nonlinear wave breaking and concomitant
three-dimensional turbulence could play an important role in the mixing of the
abyssal ocean, and hence in controlling the large-scale ocean circulation.\r\nAs
part of on-going work aimed at providing a theory for the vertical distribution
of wave breaking over sea-floor topography, in this paper we investigate the instability
of internal tides in a very simple linear model that helps us to relate the formation
of unstable regions to simple features in the sea-floor topography. For two-dimensional
tides over one-dimensional topography we find that the formation of overturning
instabilities is closely linked to the singularities in the topography shape and
that it is possible to have stable waves at the sea floor and unstable waves in
the ocean interior above.\r\nFor three-dimensional tides over two-dimensional
topography there is in addition an effect of geometric focusing of wave energy
into localized regions of high wave amplitude, and we investigate this focusing
effect in simple examples. Overall, we find that the distribution of unstable
wave breaking regions can be highly non-uniform even for very simple idealized
topography shapes."
article_processing_charge: No
article_type: original
author:
- first_name: Oliver
full_name: Bühler, Oliver
last_name: Bühler
- first_name: Caroline J
full_name: Muller, Caroline J
id: f978ccb0-3f7f-11eb-b193-b0e2bd13182b
last_name: Muller
orcid: 0000-0001-5836-5350
citation:
ama: Bühler O, Muller CJ. Instability and focusing of internal tides in the deep
ocean. Journal of Fluid Mechanics. 2007;588:1-28. doi:10.1017/s0022112007007410
apa: Bühler, O., & Muller, C. J. (2007). Instability and focusing of internal
tides in the deep ocean. Journal of Fluid Mechanics. Cambridge University
Press. https://doi.org/10.1017/s0022112007007410
chicago: Bühler, Oliver, and Caroline J Muller. “Instability and Focusing of Internal
Tides in the Deep Ocean.” Journal of Fluid Mechanics. Cambridge University
Press, 2007. https://doi.org/10.1017/s0022112007007410.
ieee: O. Bühler and C. J. Muller, “Instability and focusing of internal tides in
the deep ocean,” Journal of Fluid Mechanics, vol. 588. Cambridge University
Press, pp. 1–28, 2007.
ista: Bühler O, Muller CJ. 2007. Instability and focusing of internal tides in the
deep ocean. Journal of Fluid Mechanics. 588, 1–28.
mla: Bühler, Oliver, and Caroline J. Muller. “Instability and Focusing of Internal
Tides in the Deep Ocean.” Journal of Fluid Mechanics, vol. 588, Cambridge
University Press, 2007, pp. 1–28, doi:10.1017/s0022112007007410.
short: O. Bühler, C.J. Muller, Journal of Fluid Mechanics 588 (2007) 1–28.
date_created: 2021-02-15T14:41:45Z
date_published: 2007-10-10T00:00:00Z
date_updated: 2022-01-24T13:43:36Z
day: '10'
doi: 10.1017/s0022112007007410
extern: '1'
intvolume: ' 588'
keyword:
- mechanical engineering
- mechanics of materials
- condensed matter physics
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1017/S0022112007007410
month: '10'
oa: 1
oa_version: None
page: 1-28
publication: Journal of Fluid Mechanics
publication_identifier:
issn:
- 0022-1120
- 1469-7645
publication_status: published
publisher: Cambridge University Press
quality_controlled: '1'
status: public
title: Instability and focusing of internal tides in the deep ocean
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 588
year: '2007'
...
---
_id: '7323'
abstract:
- lang: eng
text: The main factors for reducing the consumption of a vehicle are reduction of
curb weight, air drag and increase in the drivetrain efficiency. Highly efficient
drivetrains can be developed based on PEFC technology and curb weight may be limited
by an innovative vehicle construction. In this paper, data on consumption and
efficiency of a four‐place passenger vehicle with a curb weight of 850 kg and
an H2/O2 fed PEFC/Supercap hybrid electric powertrain are presented. Hydrogen
consumption in the New European Driving Cycle is 0.67 kg H2/100 km, which corresponds
to a gasoline equivalent consumption of 2.5 l/100 km. When including the energy
needed to supply pure oxygen, the calculated consumption increases from 0.67 to
0.69–0.79 kg H2/100 km, depending on the method of oxygen production.
article_processing_charge: No
article_type: original
author:
- first_name: F. N.
full_name: Büchi, F. N.
last_name: Büchi
- first_name: G.
full_name: Paganelli, G.
last_name: Paganelli
- first_name: P.
full_name: Dietrich, P.
last_name: Dietrich
- first_name: D.
full_name: Laurent, D.
last_name: Laurent
- first_name: A.
full_name: Tsukada, A.
last_name: Tsukada
- first_name: P.
full_name: Varenne, P.
last_name: Varenne
- first_name: A.
full_name: Delfino, A.
last_name: Delfino
- first_name: R.
full_name: Kötz, R.
last_name: Kötz
- first_name: Stefan Alexander
full_name: Freunberger, Stefan Alexander
id: A8CA28E6-CE23-11E9-AD2D-EC27E6697425
last_name: Freunberger
orcid: 0000-0003-2902-5319
- first_name: P.-A.
full_name: Magne, P.-A.
last_name: Magne
- first_name: D.
full_name: Walser, D.
last_name: Walser
- first_name: D.
full_name: Olsommer, D.
last_name: Olsommer
citation:
ama: Büchi FN, Paganelli G, Dietrich P, et al. Consumption and efficiency of a passenger
car with a Hydrogen/Oxygen PEFC based hybrid electric drivetrain. Fuel Cells.
2007;7(4):329-335. doi:10.1002/fuce.200600050
apa: Büchi, F. N., Paganelli, G., Dietrich, P., Laurent, D., Tsukada, A., Varenne,
P., … Olsommer, D. (2007). Consumption and efficiency of a passenger car with
a Hydrogen/Oxygen PEFC based hybrid electric drivetrain. Fuel Cells. Wiley.
https://doi.org/10.1002/fuce.200600050
chicago: Büchi, F. N., G. Paganelli, P. Dietrich, D. Laurent, A. Tsukada, P. Varenne,
A. Delfino, et al. “Consumption and Efficiency of a Passenger Car with a Hydrogen/Oxygen
PEFC Based Hybrid Electric Drivetrain.” Fuel Cells. Wiley, 2007. https://doi.org/10.1002/fuce.200600050.
ieee: F. N. Büchi et al., “Consumption and efficiency of a passenger car
with a Hydrogen/Oxygen PEFC based hybrid electric drivetrain,” Fuel Cells,
vol. 7, no. 4. Wiley, pp. 329–335, 2007.
ista: Büchi FN, Paganelli G, Dietrich P, Laurent D, Tsukada A, Varenne P, Delfino
A, Kötz R, Freunberger SA, Magne P-A, Walser D, Olsommer D. 2007. Consumption
and efficiency of a passenger car with a Hydrogen/Oxygen PEFC based hybrid electric
drivetrain. Fuel Cells. 7(4), 329–335.
mla: Büchi, F. N., et al. “Consumption and Efficiency of a Passenger Car with a
Hydrogen/Oxygen PEFC Based Hybrid Electric Drivetrain.” Fuel Cells, vol.
7, no. 4, Wiley, 2007, pp. 329–35, doi:10.1002/fuce.200600050.
short: F.N. Büchi, G. Paganelli, P. Dietrich, D. Laurent, A. Tsukada, P. Varenne,
A. Delfino, R. Kötz, S.A. Freunberger, P.-A. Magne, D. Walser, D. Olsommer, Fuel
Cells 7 (2007) 329–335.
date_created: 2020-01-15T12:22:10Z
date_published: 2007-08-01T00:00:00Z
date_updated: 2021-01-12T08:13:04Z
day: '01'
doi: 10.1002/fuce.200600050
extern: '1'
intvolume: ' 7'
issue: '4'
language:
- iso: eng
month: '08'
oa_version: None
page: 329-335
publication: Fuel Cells
publication_identifier:
issn:
- 1615-6846
- 1615-6854
publication_status: published
publisher: Wiley
quality_controlled: '1'
status: public
title: Consumption and efficiency of a passenger car with a Hydrogen/Oxygen PEFC based
hybrid electric drivetrain
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2007'
...
---
_id: '7324'
abstract:
- lang: eng
text: Efficiency is the key parameter for the application of fuel cells in automotive
applications. The efficiency of a hydrogen/oxygen polymer electrolyte fuel cell
system is analyzed and compared to hydrogen/air systems. The analysis is performed
for the tank to electric power chain. Furthermore, the additional energy required
for using pure oxygen as a second fuel is analyzed and included in the calculation.
The results show that if hydrogen is produced from primary fossil energy carriers,
such as natural gas and pure oxygen needs to be obtained by a conventional process;
the fuel to electric current efficiency is comparable for hydrogen/oxygen and
hydrogen/air systems. However, if hydrogen and oxygen are produced by the splitting
of water, i.e., by electrolysis or by a thermochemical process, the fuel to electric
current efficiency for the hydrogen/oxygen system is clearly superior.
article_processing_charge: No
article_type: original
author:
- first_name: F. N.
full_name: Büchi, F. N.
last_name: Büchi
- first_name: Stefan Alexander
full_name: Freunberger, Stefan Alexander
id: A8CA28E6-CE23-11E9-AD2D-EC27E6697425
last_name: Freunberger
orcid: 0000-0003-2902-5319
- first_name: M.
full_name: Reum, M.
last_name: Reum
- first_name: G.
full_name: Paganelli, G.
last_name: Paganelli
- first_name: A.
full_name: Tsukada, A.
last_name: Tsukada
- first_name: P.
full_name: Dietrich, P.
last_name: Dietrich
- first_name: A.
full_name: Delfino, A.
last_name: Delfino
citation:
ama: Büchi FN, Freunberger SA, Reum M, et al. On the efficiency of an advanced automotive
fuel cell system. Fuel Cells. 2007;7(2):159-164. doi:10.1002/fuce.200500257
apa: Büchi, F. N., Freunberger, S. A., Reum, M., Paganelli, G., Tsukada, A., Dietrich,
P., & Delfino, A. (2007). On the efficiency of an advanced automotive fuel
cell system. Fuel Cells. Wiley. https://doi.org/10.1002/fuce.200500257
chicago: Büchi, F. N., Stefan Alexander Freunberger, M. Reum, G. Paganelli, A. Tsukada,
P. Dietrich, and A. Delfino. “On the Efficiency of an Advanced Automotive Fuel
Cell System.” Fuel Cells. Wiley, 2007. https://doi.org/10.1002/fuce.200500257.
ieee: F. N. Büchi et al., “On the efficiency of an advanced automotive fuel
cell system,” Fuel Cells, vol. 7, no. 2. Wiley, pp. 159–164, 2007.
ista: Büchi FN, Freunberger SA, Reum M, Paganelli G, Tsukada A, Dietrich P, Delfino
A. 2007. On the efficiency of an advanced automotive fuel cell system. Fuel Cells.
7(2), 159–164.
mla: Büchi, F. N., et al. “On the Efficiency of an Advanced Automotive Fuel Cell
System.” Fuel Cells, vol. 7, no. 2, Wiley, 2007, pp. 159–64, doi:10.1002/fuce.200500257.
short: F.N. Büchi, S.A. Freunberger, M. Reum, G. Paganelli, A. Tsukada, P. Dietrich,
A. Delfino, Fuel Cells 7 (2007) 159–164.
date_created: 2020-01-15T12:22:20Z
date_published: 2007-04-01T00:00:00Z
date_updated: 2021-01-12T08:13:04Z
day: '01'
doi: 10.1002/fuce.200500257
extern: '1'
intvolume: ' 7'
issue: '2'
language:
- iso: eng
month: '04'
oa_version: None
page: 159-164
publication: Fuel Cells
publication_identifier:
issn:
- 1615-6846
- 1615-6854
publication_status: published
publisher: Wiley
status: public
title: On the efficiency of an advanced automotive fuel cell system
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2007'
...
---
_id: '7325'
abstract:
- lang: eng
text: Our experimental results shown here disprove that finite diffusion can generally
be assumed in ac impedance models for H2/air-polymer electrolyte fuel cells (PEFCs)
to account for the diffusive transport of oxygen through the gas diffusion layer
(GDL) toward the air electrode. It is shown that the amplitude of the oxygen concentration
oscillation created as a consequence of superimposed ac current at the air electrode
is not zero at the channel/GDL interface but extends into the gas channels, at
least below modulation frequencies of fmod=10 Hz . By this, sinusoidal oxygen-concentration
oscillations within the cathode gas channels are excited locally along the flow
field. Due to the forced air convection in the cathode flow-field channels, a
coupling via the gas phase occurs downstream of the flow field. The coupling strongly
affects the local and by this the overall impedance response of the cell and evokes
the formation of a low-frequency arc in H2/air-PEFC impedance spectra. Based on
the experimental results, a qualitative model is presented explaining the local
impedance response of a segmented 200cm2H2/air PEFC.
article_number: B383
article_processing_charge: No
article_type: original
author:
- first_name: I. A.
full_name: Schneider, I. A.
last_name: Schneider
- first_name: Stefan Alexander
full_name: Freunberger, Stefan Alexander
id: A8CA28E6-CE23-11E9-AD2D-EC27E6697425
last_name: Freunberger
orcid: 0000-0003-2902-5319
- first_name: D.
full_name: Kramer, D.
last_name: Kramer
- first_name: A.
full_name: Wokaun, A.
last_name: Wokaun
- first_name: G. G.
full_name: Scherer, G. G.
last_name: Scherer
citation:
ama: 'Schneider IA, Freunberger SA, Kramer D, Wokaun A, Scherer GG. Oscillations
in gas channels: Part I. The forgotten player in impedance spectroscopy in PEFCs.
Journal of The Electrochemical Society. 2007;154(4). doi:10.1149/1.2435706'
apa: 'Schneider, I. A., Freunberger, S. A., Kramer, D., Wokaun, A., & Scherer,
G. G. (2007). Oscillations in gas channels: Part I. The forgotten player in impedance
spectroscopy in PEFCs. Journal of The Electrochemical Society. The Electrochemical
Society. https://doi.org/10.1149/1.2435706'
chicago: 'Schneider, I. A., Stefan Alexander Freunberger, D. Kramer, A. Wokaun,
and G. G. Scherer. “Oscillations in Gas Channels: Part I. The Forgotten Player
in Impedance Spectroscopy in PEFCs.” Journal of The Electrochemical Society.
The Electrochemical Society, 2007. https://doi.org/10.1149/1.2435706.'
ieee: 'I. A. Schneider, S. A. Freunberger, D. Kramer, A. Wokaun, and G. G. Scherer,
“Oscillations in gas channels: Part I. The forgotten player in impedance spectroscopy
in PEFCs,” Journal of The Electrochemical Society, vol. 154, no. 4. The
Electrochemical Society, 2007.'
ista: 'Schneider IA, Freunberger SA, Kramer D, Wokaun A, Scherer GG. 2007. Oscillations
in gas channels: Part I. The forgotten player in impedance spectroscopy in PEFCs.
Journal of The Electrochemical Society. 154(4), B383.'
mla: 'Schneider, I. A., et al. “Oscillations in Gas Channels: Part I. The Forgotten
Player in Impedance Spectroscopy in PEFCs.” Journal of The Electrochemical
Society, vol. 154, no. 4, B383, The Electrochemical Society, 2007, doi:10.1149/1.2435706.'
short: I.A. Schneider, S.A. Freunberger, D. Kramer, A. Wokaun, G.G. Scherer, Journal
of The Electrochemical Society 154 (2007).
date_created: 2020-01-15T12:22:31Z
date_published: 2007-02-09T00:00:00Z
date_updated: 2021-01-12T08:13:05Z
day: '09'
doi: 10.1149/1.2435706
extern: '1'
intvolume: ' 154'
issue: '4'
language:
- iso: eng
month: '02'
oa_version: None
publication: Journal of The Electrochemical Society
publication_identifier:
issn:
- 0013-4651
publication_status: published
publisher: The Electrochemical Society
quality_controlled: '1'
status: public
title: 'Oscillations in gas channels: Part I. The forgotten player in impedance spectroscopy
in PEFCs'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 154
year: '2007'
...
---
_id: '7704'
abstract:
- lang: eng
text: Gradients of axon guidance molecules instruct the formation of continuous
neural maps, such as the retinotopic map in the vertebrate visual system. Here
we show that molecular gradients can also instruct the formation of a discrete
neural map. In the fly olfactory system, axons of 50 classes of olfactory receptor
neurons (ORNs) and dendrites of 50 classes of projection neurons (PNs) form one-to-one
connections at discrete units called glomeruli. We provide expression, loss- and
gain-of-function data to demonstrate that the levels of transmembrane Semaphorin-1a
(Sema-1a), acting cell-autonomously as a receptor or part of a receptor complex,
direct the dendritic targeting of PNs along the dorsolateral to ventromedial axis
of the antennal lobe. Sema-1a also regulates PN axon targeting in higher olfactory
centers. Thus, graded expression of Sema-1a contributes to connection specificity
from ORNs to PNs and then to higher brain centers, ensuring proper representation
of olfactory information in the brain.
article_processing_charge: No
article_type: original
author:
- first_name: Takaki
full_name: Komiyama, Takaki
last_name: Komiyama
- first_name: Lora Beatrice Jaeger
full_name: Sweeney, Lora Beatrice Jaeger
id: 56BE8254-C4F0-11E9-8E45-0B23E6697425
last_name: Sweeney
orcid: 0000-0001-9242-5601
- first_name: Oren
full_name: Schuldiner, Oren
last_name: Schuldiner
- first_name: K. Christopher
full_name: Garcia, K. Christopher
last_name: Garcia
- first_name: Liqun
full_name: Luo, Liqun
last_name: Luo
citation:
ama: Komiyama T, Sweeney LB, Schuldiner O, Garcia KC, Luo L. Graded expression of
semaphorin-1a cell-autonomously directs dendritic targeting of olfactory projection
neurons. Cell. 2007;128(2):399-410. doi:10.1016/j.cell.2006.12.028
apa: Komiyama, T., Sweeney, L. B., Schuldiner, O., Garcia, K. C., & Luo, L.
(2007). Graded expression of semaphorin-1a cell-autonomously directs dendritic
targeting of olfactory projection neurons. Cell. Elsevier. https://doi.org/10.1016/j.cell.2006.12.028
chicago: Komiyama, Takaki, Lora B. Sweeney, Oren Schuldiner, K. Christopher Garcia,
and Liqun Luo. “Graded Expression of Semaphorin-1a Cell-Autonomously Directs Dendritic
Targeting of Olfactory Projection Neurons.” Cell. Elsevier, 2007. https://doi.org/10.1016/j.cell.2006.12.028.
ieee: T. Komiyama, L. B. Sweeney, O. Schuldiner, K. C. Garcia, and L. Luo, “Graded
expression of semaphorin-1a cell-autonomously directs dendritic targeting of olfactory
projection neurons,” Cell, vol. 128, no. 2. Elsevier, pp. 399–410, 2007.
ista: Komiyama T, Sweeney LB, Schuldiner O, Garcia KC, Luo L. 2007. Graded expression
of semaphorin-1a cell-autonomously directs dendritic targeting of olfactory projection
neurons. Cell. 128(2), 399–410.
mla: Komiyama, Takaki, et al. “Graded Expression of Semaphorin-1a Cell-Autonomously
Directs Dendritic Targeting of Olfactory Projection Neurons.” Cell, vol.
128, no. 2, Elsevier, 2007, pp. 399–410, doi:10.1016/j.cell.2006.12.028.
short: T. Komiyama, L.B. Sweeney, O. Schuldiner, K.C. Garcia, L. Luo, Cell 128 (2007)
399–410.
date_created: 2020-04-30T10:37:08Z
date_published: 2007-01-26T00:00:00Z
date_updated: 2024-01-31T10:14:48Z
day: '26'
doi: 10.1016/j.cell.2006.12.028
extern: '1'
intvolume: ' 128'
issue: '2'
language:
- iso: eng
month: '01'
oa_version: None
page: 399-410
publication: Cell
publication_identifier:
issn:
- 0092-8674
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: Graded expression of semaphorin-1a cell-autonomously directs dendritic targeting
of olfactory projection neurons
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 128
year: '2007'
...
---
_id: '7705'
abstract:
- lang: eng
text: Axon-axon interactions have been implicated in neural circuit assembly, but
the underlying mechanisms are poorly understood. Here, we show that in the Drosophila
antennal lobe, early-arriving axons of olfactory receptor neurons (ORNs) from
the antenna are required for the proper targeting of late-arriving ORN axons from
the maxillary palp (MP). Semaphorin-1a is required for targeting of all MP but
only half of the antennal ORN classes examined. Sema-1a acts nonautonomously to
control ORN axon-axon interactions, in contrast to its cell-autonomous function
in olfactory projection neurons. Phenotypic and genetic interaction analyses implicate
PlexinA as the Sema-1a receptor in ORN targeting. Sema-1a on antennal ORN axons
is required for correct targeting of MP axons within the antennal lobe, while
interactions amongst MP axons facilitate their entry into the antennal lobe. We
propose that Sema-1a/PlexinA-mediated repulsion provides a mechanism by which
early-arriving ORN axons constrain the target choices of late-arriving axons.
article_processing_charge: No
article_type: original
author:
- first_name: Lora Beatrice Jaeger
full_name: Sweeney, Lora Beatrice Jaeger
id: 56BE8254-C4F0-11E9-8E45-0B23E6697425
last_name: Sweeney
orcid: 0000-0001-9242-5601
- first_name: Africa
full_name: Couto, Africa
last_name: Couto
- first_name: Ya-Hui
full_name: Chou, Ya-Hui
last_name: Chou
- first_name: Daniela
full_name: Berdnik, Daniela
last_name: Berdnik
- first_name: Barry J.
full_name: Dickson, Barry J.
last_name: Dickson
- first_name: Liqun
full_name: Luo, Liqun
last_name: Luo
- first_name: Takaki
full_name: Komiyama, Takaki
last_name: Komiyama
citation:
ama: Sweeney LB, Couto A, Chou Y-H, et al. Temporal target restriction of olfactory
receptor neurons by semaphorin-1a/plexinA-mediated axon-axon interactions. Neuron.
2007;53(2):185-200. doi:10.1016/j.neuron.2006.12.022
apa: Sweeney, L. B., Couto, A., Chou, Y.-H., Berdnik, D., Dickson, B. J., Luo, L.,
& Komiyama, T. (2007). Temporal target restriction of olfactory receptor neurons
by semaphorin-1a/plexinA-mediated axon-axon interactions. Neuron. Elsevier.
https://doi.org/10.1016/j.neuron.2006.12.022
chicago: Sweeney, Lora B., Africa Couto, Ya-Hui Chou, Daniela Berdnik, Barry J.
Dickson, Liqun Luo, and Takaki Komiyama. “Temporal Target Restriction of Olfactory
Receptor Neurons by Semaphorin-1a/PlexinA-Mediated Axon-Axon Interactions.” Neuron.
Elsevier, 2007. https://doi.org/10.1016/j.neuron.2006.12.022.
ieee: L. B. Sweeney et al., “Temporal target restriction of olfactory receptor
neurons by semaphorin-1a/plexinA-mediated axon-axon interactions,” Neuron,
vol. 53, no. 2. Elsevier, pp. 185–200, 2007.
ista: Sweeney LB, Couto A, Chou Y-H, Berdnik D, Dickson BJ, Luo L, Komiyama T. 2007.
Temporal target restriction of olfactory receptor neurons by semaphorin-1a/plexinA-mediated
axon-axon interactions. Neuron. 53(2), 185–200.
mla: Sweeney, Lora B., et al. “Temporal Target Restriction of Olfactory Receptor
Neurons by Semaphorin-1a/PlexinA-Mediated Axon-Axon Interactions.” Neuron,
vol. 53, no. 2, Elsevier, 2007, pp. 185–200, doi:10.1016/j.neuron.2006.12.022.
short: L.B. Sweeney, A. Couto, Y.-H. Chou, D. Berdnik, B.J. Dickson, L. Luo, T.
Komiyama, Neuron 53 (2007) 185–200.
date_created: 2020-04-30T10:37:24Z
date_published: 2007-01-18T00:00:00Z
date_updated: 2024-01-31T10:14:39Z
day: '18'
doi: 10.1016/j.neuron.2006.12.022
extern: '1'
intvolume: ' 53'
issue: '2'
language:
- iso: eng
month: '01'
oa_version: None
page: 185-200
publication: Neuron
publication_identifier:
issn:
- 0896-6273
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: Temporal target restriction of olfactory receptor neurons by semaphorin-1a/plexinA-mediated
axon-axon interactions
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 53
year: '2007'
...
---
_id: '7753'
abstract:
- lang: eng
text: 'In many species, females show reduced expression of a trait that is under
sexual selection in males, and this expression is thought to be maintained through
genetic associations with the male phenotype. However, there is also the potential
for the female trait to convey an advantage in intrasexual conflicts over resources.
We tested this hypothesis in a feral population of Soay sheep, in which males
and females have a polymorphism for horn development, producing either full (normal
horned), reduced (scurred) or no (polled, females only) horns. During the lambing
period, females who possessed horns were more likely to initiate and win aggressive
interactions, independent of age, weight and birthing status. The occurrence of
aggression was also context dependent, decreasing over the lambing period and
associated with local density. Our results demonstrate that a trait that confers
benefits to males during intrasexual competition for mates may also be used by
females in intrasexual competition over resources: males use weaponry to gain
mates, whereas females use weaponry to gain food.'
article_processing_charge: No
article_type: original
author:
- first_name: Matthew Richard
full_name: Robinson, Matthew Richard
id: E5D42276-F5DA-11E9-8E24-6303E6697425
last_name: Robinson
orcid: 0000-0001-8982-8813
- first_name: Loeske E.B
full_name: Kruuk, Loeske E.B
last_name: Kruuk
citation:
ama: 'Robinson MR, Kruuk LE. Function of weaponry in females: The use of horns in
intrasexual competition for resources in female Soay sheep. Biology Letters.
2007;3(6):651-654. doi:10.1098/rsbl.2007.0278'
apa: 'Robinson, M. R., & Kruuk, L. E. . (2007). Function of weaponry in females:
The use of horns in intrasexual competition for resources in female Soay sheep.
Biology Letters. The Royal Society. https://doi.org/10.1098/rsbl.2007.0278'
chicago: 'Robinson, Matthew Richard, and Loeske E.B Kruuk. “Function of Weaponry
in Females: The Use of Horns in Intrasexual Competition for Resources in Female
Soay Sheep.” Biology Letters. The Royal Society, 2007. https://doi.org/10.1098/rsbl.2007.0278.'
ieee: 'M. R. Robinson and L. E. . Kruuk, “Function of weaponry in females: The use
of horns in intrasexual competition for resources in female Soay sheep,” Biology
Letters, vol. 3, no. 6. The Royal Society, pp. 651–654, 2007.'
ista: 'Robinson MR, Kruuk LE. 2007. Function of weaponry in females: The use of
horns in intrasexual competition for resources in female Soay sheep. Biology Letters.
3(6), 651–654.'
mla: 'Robinson, Matthew Richard, and Loeske E. .. Kruuk. “Function of Weaponry in
Females: The Use of Horns in Intrasexual Competition for Resources in Female Soay
Sheep.” Biology Letters, vol. 3, no. 6, The Royal Society, 2007, pp. 651–54,
doi:10.1098/rsbl.2007.0278.'
short: M.R. Robinson, L.E.. Kruuk, Biology Letters 3 (2007) 651–654.
date_created: 2020-04-30T11:02:28Z
date_published: 2007-08-21T00:00:00Z
date_updated: 2021-01-12T08:15:18Z
day: '21'
doi: 10.1098/rsbl.2007.0278
extern: '1'
external_id:
pmid:
- '17711817'
intvolume: ' 3'
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1098/rsbl.2007.0278
month: '08'
oa: 1
oa_version: Published Version
page: 651-654
pmid: 1
publication: Biology Letters
publication_identifier:
issn:
- 1744-9561
- 1744-957X
publication_status: published
publisher: The Royal Society
quality_controlled: '1'
status: public
title: 'Function of weaponry in females: The use of horns in intrasexual competition
for resources in female Soay sheep'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 3
year: '2007'
...
---
_id: '7780'
abstract:
- lang: eng
text: 'We used single-channel electrical recordings and Langevin molecular dynamics
simulations to explore the electrophoretic translocation of various β-hairpin
peptides across the staphylococcal α-hemolysin (αHL) protein pore at single-molecule
resolution. The β-hairpin peptides, which varied in their folding properties,
corresponded to the C terminal residues of the B1 domain of protein G. The translocation
time was strongly dependent on the electric force and was correlated with the
folding features of the β-hairpin peptides. Highly unfolded peptides entered the
pore in an extended conformation, resulting in fast single-file translocation
events. In contrast, the translocation of the folded β-hairpin peptides occurred
more slowly. In this case, the β-hairpin peptides traversed the αHL pore in a
misfolded or fully folded conformation. This study demonstrates that the interaction
between a polypeptide and a β-barrel protein pore is dependent on the folding
features of the polypeptide. '
article_processing_charge: No
article_type: original
author:
- first_name: Carl Peter
full_name: Goodrich, Carl Peter
id: EB352CD2-F68A-11E9-89C5-A432E6697425
last_name: Goodrich
orcid: 0000-0002-1307-5074
- first_name: Serdal
full_name: Kirmizialtin, Serdal
last_name: Kirmizialtin
- first_name: Beatrice M.
full_name: Huyghues-Despointes, Beatrice M.
last_name: Huyghues-Despointes
- first_name: Aiping
full_name: Zhu, Aiping
last_name: Zhu
- first_name: J. Martin
full_name: Scholtz, J. Martin
last_name: Scholtz
- first_name: Dmitrii E.
full_name: Makarov, Dmitrii E.
last_name: Makarov
- first_name: Liviu
full_name: Movileanu, Liviu
last_name: Movileanu
citation:
ama: Goodrich CP, Kirmizialtin S, Huyghues-Despointes BM, et al. Single-molecule
electrophoresis of β-hairpin peptides by electrical recordings and Langevin dynamics
simulations. The Journal of Physical Chemistry B. 2007;111(13):3332-3335.
doi:10.1021/jp071364h
apa: Goodrich, C. P., Kirmizialtin, S., Huyghues-Despointes, B. M., Zhu, A., Scholtz,
J. M., Makarov, D. E., & Movileanu, L. (2007). Single-molecule electrophoresis
of β-hairpin peptides by electrical recordings and Langevin dynamics simulations.
The Journal of Physical Chemistry B. American Chemical Society. https://doi.org/10.1021/jp071364h
chicago: Goodrich, Carl Peter, Serdal Kirmizialtin, Beatrice M. Huyghues-Despointes,
Aiping Zhu, J. Martin Scholtz, Dmitrii E. Makarov, and Liviu Movileanu. “Single-Molecule
Electrophoresis of β-Hairpin Peptides by Electrical Recordings and Langevin Dynamics
Simulations.” The Journal of Physical Chemistry B. American Chemical Society,
2007. https://doi.org/10.1021/jp071364h.
ieee: C. P. Goodrich et al., “Single-molecule electrophoresis of β-hairpin
peptides by electrical recordings and Langevin dynamics simulations,” The Journal
of Physical Chemistry B, vol. 111, no. 13. American Chemical Society, pp.
3332–3335, 2007.
ista: Goodrich CP, Kirmizialtin S, Huyghues-Despointes BM, Zhu A, Scholtz JM, Makarov
DE, Movileanu L. 2007. Single-molecule electrophoresis of β-hairpin peptides by
electrical recordings and Langevin dynamics simulations. The Journal of Physical
Chemistry B. 111(13), 3332–3335.
mla: Goodrich, Carl Peter, et al. “Single-Molecule Electrophoresis of β-Hairpin
Peptides by Electrical Recordings and Langevin Dynamics Simulations.” The Journal
of Physical Chemistry B, vol. 111, no. 13, American Chemical Society, 2007,
pp. 3332–35, doi:10.1021/jp071364h.
short: C.P. Goodrich, S. Kirmizialtin, B.M. Huyghues-Despointes, A. Zhu, J.M. Scholtz,
D.E. Makarov, L. Movileanu, The Journal of Physical Chemistry B 111 (2007) 3332–3335.
date_created: 2020-04-30T12:19:15Z
date_published: 2007-03-13T00:00:00Z
date_updated: 2021-01-12T08:15:29Z
day: '13'
doi: 10.1021/jp071364h
extern: '1'
intvolume: ' 111'
issue: '13'
language:
- iso: eng
month: '03'
oa_version: None
page: 3332-3335
publication: The Journal of Physical Chemistry B
publication_identifier:
issn:
- 1520-6106
- 1520-5207
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
status: public
title: Single-molecule electrophoresis of β-hairpin peptides by electrical recordings
and Langevin dynamics simulations
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 111
year: '2007'
...
---
_id: '7781'
abstract:
- lang: eng
text: Males are predicted to compete for reproductive opportunities, with sexual
selection driving the evolution of large body size and weaponry through the advantage
they confer for access to females. Few studies have explored potential trade‐offs
of investment in secondary sexual traits between different components of fitness
or tested for sexually antagonistic selection pressures. These factors may provide
explanations for observed polymorphisms in both form and quality of secondary
sexual traits. We report here an analysis of selection on horn phenotype in a
feral population of Soay sheep (Ovis aries) on the island of Hirta, St. Kilda,
Scotland. Soay sheep display a phenotypic polymorphism for horn type with males
growing either normal or reduced (scurred) horns, and females growing either normal,
scurred, or no (polled) horns; further variation in size exists within horn morphs.
We show that horn phenotype and the size of the trait displayed is subject to
different selection pressures in males and females, generating sexually antagonistic
selection. Furthermore, there was evidence of a trade‐off between breeding success
and longevity in normal‐horned males, with both the normal horn type and larger
horn size being associated with greater annual breeding success but reduced longevity.
Therefore, selection through lifetime breeding success was not found to act upon
horn phenotype in males. In females, a negative association of annual breeding
success within the normal‐horned phenotype did not result in a significant difference
in lifetime fitness when compared to scurred individuals, as no significant difference
in longevity was found. However, increased horn size within this group was negatively
associated with breeding success and longevity. Females without horns (polled)
suffered reduced longevity and thus reduced lifetime breeding success relative
the other horn morphs. Our results therefore suggest that trade‐offs between different
components of fitness and antagonistic selection between the sexes may maintain
genetic variation for secondary sexual traits within a population.
article_processing_charge: No
article_type: original
author:
- first_name: Matthew Richard
full_name: Robinson, Matthew Richard
id: E5D42276-F5DA-11E9-8E24-6303E6697425
last_name: Robinson
orcid: 0000-0001-8982-8813
- first_name: Jill G.
full_name: Pilkington, Jill G.
last_name: Pilkington
- first_name: Tim H.
full_name: Clutton-Brock, Tim H.
last_name: Clutton-Brock
- first_name: Josephine M.
full_name: Pemberton, Josephine M.
last_name: Pemberton
- first_name: Loeske E.B.
full_name: Kruuk, Loeske E.B.
last_name: Kruuk
citation:
ama: 'Robinson MR, Pilkington JG, Clutton-Brock TH, Pemberton JM, Kruuk LEB. Live
fast, die young: Trade-offs between fitness components and sexually antagonistic
selection on weaponry in soay sheep. Evolution. 2007;60(10):2168-2181.
doi:10.1111/j.0014-3820.2006.tb01854.x'
apa: 'Robinson, M. R., Pilkington, J. G., Clutton-Brock, T. H., Pemberton, J. M.,
& Kruuk, L. E. B. (2007). Live fast, die young: Trade-offs between fitness
components and sexually antagonistic selection on weaponry in soay sheep. Evolution.
Wiley. https://doi.org/10.1111/j.0014-3820.2006.tb01854.x'
chicago: 'Robinson, Matthew Richard, Jill G. Pilkington, Tim H. Clutton-Brock, Josephine
M. Pemberton, and Loeske E.B. Kruuk. “Live Fast, Die Young: Trade-Offs between
Fitness Components and Sexually Antagonistic Selection on Weaponry in Soay Sheep.”
Evolution. Wiley, 2007. https://doi.org/10.1111/j.0014-3820.2006.tb01854.x.'
ieee: 'M. R. Robinson, J. G. Pilkington, T. H. Clutton-Brock, J. M. Pemberton, and
L. E. B. Kruuk, “Live fast, die young: Trade-offs between fitness components and
sexually antagonistic selection on weaponry in soay sheep,” Evolution,
vol. 60, no. 10. Wiley, pp. 2168–2181, 2007.'
ista: 'Robinson MR, Pilkington JG, Clutton-Brock TH, Pemberton JM, Kruuk LEB. 2007.
Live fast, die young: Trade-offs between fitness components and sexually antagonistic
selection on weaponry in soay sheep. Evolution. 60(10), 2168–2181.'
mla: 'Robinson, Matthew Richard, et al. “Live Fast, Die Young: Trade-Offs between
Fitness Components and Sexually Antagonistic Selection on Weaponry in Soay Sheep.”
Evolution, vol. 60, no. 10, Wiley, 2007, pp. 2168–81, doi:10.1111/j.0014-3820.2006.tb01854.x.'
short: M.R. Robinson, J.G. Pilkington, T.H. Clutton-Brock, J.M. Pemberton, L.E.B.
Kruuk, Evolution 60 (2007) 2168–2181.
date_created: 2020-04-30T13:01:47Z
date_published: 2007-05-08T00:00:00Z
date_updated: 2021-01-12T08:15:30Z
day: '08'
doi: 10.1111/j.0014-3820.2006.tb01854.x
extern: '1'
intvolume: ' 60'
issue: '10'
language:
- iso: eng
month: '05'
oa_version: None
page: 2168-2181
publication: Evolution
publication_identifier:
issn:
- 0014-3820
publication_status: published
publisher: Wiley
quality_controlled: '1'
status: public
title: 'Live fast, die young: Trade-offs between fitness components and sexually antagonistic
selection on weaponry in soay sheep'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 60
year: '2007'
...
---
_id: '8027'
abstract:
- lang: eng
text: Gating deficits and hallucinatory sensations are prominent symptoms of schizophrenia.
Comparing these abnormalities with the failure modes of network models is an interesting
way to explore how they arise. We present a network model that can both propagate
and gate signals. The model exhibits effects reminiscent of clinically observed
pathologies when the balance between excitation and inhibition that it requires
is not properly maintained.
article_processing_charge: No
article_type: original
author:
- first_name: Tim P
full_name: Vogels, Tim P
id: CB6FF8D2-008F-11EA-8E08-2637E6697425
last_name: Vogels
orcid: 0000-0003-3295-6181
- first_name: L.
full_name: Abbott, L.
last_name: Abbott
citation:
ama: 'Vogels TP, Abbott L. Gating deficits in model networks: A path to schizophrenia?
Pharmacopsychiatry. 2007;40(S 1):S73-S77. doi:10.1055/s-2007-992130'
apa: 'Vogels, T. P., & Abbott, L. (2007). Gating deficits in model networks:
A path to schizophrenia? Pharmacopsychiatry. Thieme. https://doi.org/10.1055/s-2007-992130'
chicago: 'Vogels, Tim P, and L. Abbott. “Gating Deficits in Model Networks: A Path
to Schizophrenia?” Pharmacopsychiatry. Thieme, 2007. https://doi.org/10.1055/s-2007-992130.'
ieee: 'T. P. Vogels and L. Abbott, “Gating deficits in model networks: A path to
schizophrenia?,” Pharmacopsychiatry, vol. 40, no. S 1. Thieme, pp. S73–S77,
2007.'
ista: 'Vogels TP, Abbott L. 2007. Gating deficits in model networks: A path to schizophrenia?
Pharmacopsychiatry. 40(S 1), S73–S77.'
mla: 'Vogels, Tim P., and L. Abbott. “Gating Deficits in Model Networks: A Path
to Schizophrenia?” Pharmacopsychiatry, vol. 40, no. S 1, Thieme, 2007,
pp. S73–77, doi:10.1055/s-2007-992130.'
short: T.P. Vogels, L. Abbott, Pharmacopsychiatry 40 (2007) S73–S77.
date_created: 2020-06-25T13:11:37Z
date_published: 2007-12-01T00:00:00Z
date_updated: 2021-01-12T08:16:36Z
day: '01'
doi: 10.1055/s-2007-992130
extern: '1'
external_id:
pmid:
- '18080946'
intvolume: ' 40'
issue: S 1
language:
- iso: eng
month: '12'
oa_version: None
page: S73-S77
pmid: 1
publication: Pharmacopsychiatry
publication_identifier:
issn:
- 0176-3679
- 1439-0795
publication_status: published
publisher: Thieme
quality_controlled: '1'
status: public
title: 'Gating deficits in model networks: A path to schizophrenia?'
type: journal_article
user_id: D865714E-FA4E-11E9-B85B-F5C5E5697425
volume: 40
year: '2007'
...
---
_id: '167'
abstract:
- lang: eng
text: This book contains research articles on Diophantine Geometry, written by participants
of a research program held at the Ennio De Giorgi Mathematical Research Center
in Pisa, Italy, during the period April – July 2005. The authors are eminent experts
in the field. Several subfields of the main topic are presented; the volume thus
is particularly useful to get a broad overview of recent research developments.
alternative_title:
- CRM Series
article_processing_charge: No
arxiv: 1
author:
- first_name: Timothy D
full_name: Browning, Timothy D
id: 35827D50-F248-11E8-B48F-1D18A9856A87
last_name: Browning
orcid: 0000-0002-8314-0177
- first_name: Roger
full_name: Heath Brown, Roger
last_name: Heath Brown
citation:
ama: 'Browning TD, Heath Brown R. Simultaneous equal sums of three powers. In: Zannier
U, ed. Diophantine Geometry. Vol 4. Edizioni della Normale; 2007:93-100.'
apa: Browning, T. D., & Heath Brown, R. (2007). Simultaneous equal sums of three
powers. In U. Zannier (Ed.), Diophantine Geometry (Vol. 4, pp. 93–100).
Edizioni della Normale.
chicago: Browning, Timothy D, and Roger Heath Brown. “Simultaneous Equal Sums of
Three Powers.” In Diophantine Geometry, edited by Umberto Zannier, 4:93–100.
Edizioni della Normale, 2007.
ieee: T. D. Browning and R. Heath Brown, “Simultaneous equal sums of three powers,”
in Diophantine Geometry, vol. 4, U. Zannier, Ed. Edizioni della Normale,
2007, pp. 93–100.
ista: 'Browning TD, Heath Brown R. 2007.Simultaneous equal sums of three powers.
In: Diophantine Geometry. CRM Series, vol. 4, 93–100.'
mla: Browning, Timothy D., and Roger Heath Brown. “Simultaneous Equal Sums of Three
Powers.” Diophantine Geometry, edited by Umberto Zannier, vol. 4, Edizioni
della Normale, 2007, pp. 93–100.
short: T.D. Browning, R. Heath Brown, in:, U. Zannier (Ed.), Diophantine Geometry,
Edizioni della Normale, 2007, pp. 93–100.
date_created: 2018-12-11T11:44:59Z
date_published: 2007-01-01T00:00:00Z
date_updated: 2021-01-12T06:52:24Z
day: '01'
editor:
- first_name: Umberto
full_name: Zannier, Umberto
last_name: Zannier
extern: '1'
external_id:
arxiv:
- '0509152'
intvolume: ' 4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/math/0509152
month: '01'
oa: 1
oa_version: Preprint
page: 93 - 100
publication: Diophantine Geometry
publication_status: published
publisher: Edizioni della Normale
publist_id: '7754'
quality_controlled: '1'
status: public
title: Simultaneous equal sums of three powers
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 4
year: '2007'
...
---
_id: '1750'
abstract:
- lang: eng
text: The authors investigate the composition profile of SiGe islands after capping
with Si to form quantum dots, using a two step etching procedure and atomic force
microscopy. Initially, the Si capping layers are removed by etching selectively
Si over Ge and then the composition of the disclosed islands is addressed by selectively
etching Ge over Si. For samples grown at 580 °C the authors show that even when
overgrowth leads to a flat Si surface and the islands undergo strong morphological
changes, a Ge-rich core region is still preserved in the dot. At high growth and
overgrowth temperatures (740 °C), the experiments show that the newly formed base
of the buried islands is more Si rich than their top. Furthermore, the authors
find that for the growth conditions used, no lateral motion takes place during
capping.
author:
- first_name: Georgios
full_name: Georgios Katsaros
id: 38DB5788-F248-11E8-B48F-1D18A9856A87
last_name: Katsaros
- first_name: Mathieu
full_name: Stoffel, Mathieu
last_name: Stoffel
- first_name: Armando
full_name: Rastelli, Armando
last_name: Rastelli
- first_name: Oliver
full_name: Schmidt, Oliver G
last_name: Schmidt
- first_name: Klaus
full_name: Kern, Klaus
last_name: Kern
- first_name: Jerry
full_name: Tersoff, Jerry
last_name: Tersoff
citation:
ama: Katsaros G, Stoffel M, Rastelli A, Schmidt O, Kern K, Tersoff J. Three-dimensional
isocompositional profiles of buried SiGeSi (001) islands. Applied Physics Letters.
2007;91(1). doi:10.1063/1.2752730
apa: Katsaros, G., Stoffel, M., Rastelli, A., Schmidt, O., Kern, K., & Tersoff,
J. (2007). Three-dimensional isocompositional profiles of buried SiGeSi (001)
islands. Applied Physics Letters. American Institute of Physics. https://doi.org/10.1063/1.2752730
chicago: Katsaros, Georgios, Mathieu Stoffel, Armando Rastelli, Oliver Schmidt,
Klaus Kern, and Jerry Tersoff. “Three-Dimensional Isocompositional Profiles of
Buried SiGeSi (001) Islands.” Applied Physics Letters. American Institute
of Physics, 2007. https://doi.org/10.1063/1.2752730.
ieee: G. Katsaros, M. Stoffel, A. Rastelli, O. Schmidt, K. Kern, and J. Tersoff,
“Three-dimensional isocompositional profiles of buried SiGeSi (001) islands,”
Applied Physics Letters, vol. 91, no. 1. American Institute of Physics,
2007.
ista: Katsaros G, Stoffel M, Rastelli A, Schmidt O, Kern K, Tersoff J. 2007. Three-dimensional
isocompositional profiles of buried SiGeSi (001) islands. Applied Physics Letters.
91(1).
mla: Katsaros, Georgios, et al. “Three-Dimensional Isocompositional Profiles of
Buried SiGeSi (001) Islands.” Applied Physics Letters, vol. 91, no. 1,
American Institute of Physics, 2007, doi:10.1063/1.2752730.
short: G. Katsaros, M. Stoffel, A. Rastelli, O. Schmidt, K. Kern, J. Tersoff, Applied
Physics Letters 91 (2007).
date_created: 2018-12-11T11:53:48Z
date_published: 2007-01-01T00:00:00Z
date_updated: 2021-01-12T06:52:58Z
day: '01'
doi: 10.1063/1.2752730
extern: 1
intvolume: ' 91'
issue: '1'
month: '01'
publication: Applied Physics Letters
publication_status: published
publisher: American Institute of Physics
publist_id: '5375'
quality_controlled: 0
status: public
title: Three-dimensional isocompositional profiles of buried SiGeSi (001) islands
type: journal_article
volume: 91
year: '2007'
...
---
_id: '1762'
abstract:
- lang: eng
text: In quantum information science, the phase of a wave function plays an important
role in encoding information. Although most experiments in this field rely on
dynamic effects to manipulate this information, an alternative approach is to
use geometric phase, which has been argued to have potential fault tolerance.
We demonstrated the controlled accumulation of a geometric phase, Berry's phase,
in a superconducting qubit; we manipulated the qubit geometrically by means of
microwave radiation and observed the accumulated phase in an interference experiment.
We found excellent agreement with Berry's predictions and also observed a geometry-dependent
contribution to dephasing.
acknowledgement: Supported by the EC via an Intra-European Marie Curie Fellowship
(P.J.L.), the Natural Sciences and Engineering Research Council of Canada, Canadian
Institute for Advanced Research, and Fonds Québécois de la Recherche sur la Nature
et les Technologies (A.B.), the National Security Agency under the Army Research
Office, NSF, and Yale University (D.I.S., L.F., and R.J.S.), Consiglio Nazionale
delle Ricerche–Istituto di Cibernetica, Pozzuoli, Italy (L.F.), the Ontario Research
Development Challenge Fund and Mathematics of Information Technology and Complex
Systems (J.M.G.), the Swiss National Science Foundation, and ETH Zürich
author:
- first_name: Peter
full_name: Leek, Peter J
last_name: Leek
- first_name: Johannes M
full_name: Johannes Fink
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
- first_name: Alexandre
full_name: Blais, Alexandre
last_name: Blais
- first_name: R
full_name: Bianchetti, R
last_name: Bianchetti
- first_name: M
full_name: Göppl, M
last_name: Göppl
- first_name: Jay
full_name: Gambetta, Jay M
last_name: Gambetta
- first_name: David
full_name: Schuster, David I
last_name: Schuster
- first_name: Luigi
full_name: Frunzio, Luigi
last_name: Frunzio
- first_name: Robert
full_name: Schoelkopf, Robert J
last_name: Schoelkopf
- first_name: Andreas
full_name: Wallraff, Andreas
last_name: Wallraff
citation:
ama: Leek P, Fink JM, Blais A, et al. Observation of Berry’s phase in a solid-state
qubit. Science. 2007;318(5858):1889-1892. doi:10.1126/science.1149858
apa: Leek, P., Fink, J. M., Blais, A., Bianchetti, R., Göppl, M., Gambetta, J.,
… Wallraff, A. (2007). Observation of Berry’s phase in a solid-state qubit. Science.
American Association for the Advancement of Science. https://doi.org/10.1126/science.1149858
chicago: Leek, Peter, Johannes M Fink, Alexandre Blais, R Bianchetti, M Göppl, Jay
Gambetta, David Schuster, Luigi Frunzio, Robert Schoelkopf, and Andreas Wallraff.
“Observation of Berry’s Phase in a Solid-State Qubit.” Science. American
Association for the Advancement of Science, 2007. https://doi.org/10.1126/science.1149858.
ieee: P. Leek et al., “Observation of Berry’s phase in a solid-state qubit,”
Science, vol. 318, no. 5858. American Association for the Advancement of
Science, pp. 1889–1892, 2007.
ista: Leek P, Fink JM, Blais A, Bianchetti R, Göppl M, Gambetta J, Schuster D, Frunzio
L, Schoelkopf R, Wallraff A. 2007. Observation of Berry’s phase in a solid-state
qubit. Science. 318(5858), 1889–1892.
mla: Leek, Peter, et al. “Observation of Berry’s Phase in a Solid-State Qubit.”
Science, vol. 318, no. 5858, American Association for the Advancement of
Science, 2007, pp. 1889–92, doi:10.1126/science.1149858.
short: P. Leek, J.M. Fink, A. Blais, R. Bianchetti, M. Göppl, J. Gambetta, D. Schuster,
L. Frunzio, R. Schoelkopf, A. Wallraff, Science 318 (2007) 1889–1892.
date_created: 2018-12-11T11:53:52Z
date_published: 2007-12-27T00:00:00Z
date_updated: 2021-01-12T06:53:02Z
day: '27'
doi: 10.1126/science.1149858
extern: 1
intvolume: ' 318'
issue: '5858'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/0711.0218
month: '12'
oa: 1
page: 1889 - 1892
publication: Science
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '5360'
quality_controlled: 0
status: public
title: Observation of Berry's phase in a solid-state qubit
type: journal_article
volume: 318
year: '2007'
...
---
_id: '1797'
abstract:
- lang: eng
text: Intrinsically photosensitive melanopsin-containing retinal ganglion cells
(ipRGCs) control important physiological processes, including the circadian rhythm,
the pupillary reflex, and the suppression of locomotor behavior (reviewed in [1]).
ipRGCs are also activated by classical photoreceptors, the rods and cones, through
local retinal circuits [2, 3]. ipRGCs can be transsynaptically labeled through
the pupillary-reflex circuit with the derivatives of the Bartha strain of the
alphaherpesvirus pseudorabies virus(PRV) [4, 5] that express GFP [6-12]. Bartha-strain
derivatives spread only in the retrograde direction [13]. There is evidence that
infected cells function normally for a while during GFP expression [7]. Here we
combine transsynaptic PRV labeling, two-photon laser microscopy, and electrophysiological
techniques to trace the local circuit of different ipRGC subtypes in the mouse
retina and record light-evoked activity from the transsynaptically labeled ganglion
cells. First, we show that ipRGCs are connected by monostratified amacrine cells
that provide strong inhibition from classical-photoreceptor-driven circuits. Second,
we show evidence that dopaminergic interplexiform cells are synaptically connected
to ipRGCs. The latter finding provides a circuitry link between light-dark adaptation
and ipRGC function.
acknowledgement: This study was supported by Office of Naval Research Multidisciplinary
University Research Initiative [ONR MURI] and Naval International Cooperative Opportunities
in Science and Technology Program [NICOP] grants, a Marie Curie Excellence Grant,
a Human Frontier Science Program [HFSP] Young Investigator grant, and Friedrich
Miescher Institute funds to B.R.
author:
- first_name: Tim
full_name: Viney, Tim J
last_name: Viney
- first_name: Kamill
full_name: Bálint, Kamill
last_name: Bálint
- first_name: Dániel
full_name: Hillier, Dániel
last_name: Hillier
- first_name: Sandra
full_name: Sandra Siegert
id: 36ACD32E-F248-11E8-B48F-1D18A9856A87
last_name: Siegert
orcid: 0000-0001-8635-0877
- first_name: Zsolt
full_name: Boldogköi, Zsolt S
last_name: Boldogköi
- first_name: Lynn
full_name: Enquist, Lynn W
last_name: Enquist
- first_name: Markus
full_name: Meister, Markus
last_name: Meister
- first_name: Constance
full_name: Cepko, Constance L
last_name: Cepko
- first_name: Botond
full_name: Roska, Botond M
last_name: Roska
citation:
ama: Viney T, Bálint K, Hillier D, et al. Local retinal circuits of melanopsin-containing
ganglion cells identified by transsynaptic viral tracing. Current Biology.
2007;17(11):981-988. doi:10.1016/j.cub.2007.04.058
apa: Viney, T., Bálint, K., Hillier, D., Siegert, S., Boldogköi, Z., Enquist, L.,
… Roska, B. (2007). Local retinal circuits of melanopsin-containing ganglion cells
identified by transsynaptic viral tracing. Current Biology. Cell Press.
https://doi.org/10.1016/j.cub.2007.04.058
chicago: Viney, Tim, Kamill Bálint, Dániel Hillier, Sandra Siegert, Zsolt Boldogköi,
Lynn Enquist, Markus Meister, Constance Cepko, and Botond Roska. “Local Retinal
Circuits of Melanopsin-Containing Ganglion Cells Identified by Transsynaptic Viral
Tracing.” Current Biology. Cell Press, 2007. https://doi.org/10.1016/j.cub.2007.04.058.
ieee: T. Viney et al., “Local retinal circuits of melanopsin-containing ganglion
cells identified by transsynaptic viral tracing,” Current Biology, vol.
17, no. 11. Cell Press, pp. 981–988, 2007.
ista: Viney T, Bálint K, Hillier D, Siegert S, Boldogköi Z, Enquist L, Meister M,
Cepko C, Roska B. 2007. Local retinal circuits of melanopsin-containing ganglion
cells identified by transsynaptic viral tracing. Current Biology. 17(11), 981–988.
mla: Viney, Tim, et al. “Local Retinal Circuits of Melanopsin-Containing Ganglion
Cells Identified by Transsynaptic Viral Tracing.” Current Biology, vol.
17, no. 11, Cell Press, 2007, pp. 981–88, doi:10.1016/j.cub.2007.04.058.
short: T. Viney, K. Bálint, D. Hillier, S. Siegert, Z. Boldogköi, L. Enquist, M.
Meister, C. Cepko, B. Roska, Current Biology 17 (2007) 981–988.
date_created: 2018-12-11T11:54:04Z
date_published: 2007-06-05T00:00:00Z
date_updated: 2021-01-12T06:53:15Z
day: '05'
doi: 10.1016/j.cub.2007.04.058
extern: 1
intvolume: ' 17'
issue: '11'
month: '06'
page: 981 - 988
publication: Current Biology
publication_status: published
publisher: Cell Press
publist_id: '5313'
quality_controlled: 0
status: public
title: Local retinal circuits of melanopsin-containing ganglion cells identified by
transsynaptic viral tracing
type: journal_article
volume: 17
year: '2007'
...
---
_id: '1964'
abstract:
- lang: eng
text: Complex I of respiratory chains plays a central role in cellular energy production.
Mutations in its subunits lead to many human neurodegenerative diseases. Recently,
a first atomic structure of the hydrophilic domain of complex I from Thermus thermophilus
was determined. This domain represents a catalytic core of the enzyme. It consists
of eight different subunits, contains all the redox centers, and comprises more
than half of the entire complex. In this review, novel mechanistic implications
of the structure are discussed, and the effects of many known mutations of complex
I subunits are interpreted in a structural context.
author:
- first_name: Leonid A
full_name: Leonid Sazanov
id: 338D39FE-F248-11E8-B48F-1D18A9856A87
last_name: Sazanov
orcid: 0000-0002-0977-7989
citation:
ama: 'Sazanov LA. Respiratory complex I: Mechanistic and structural insights provided
by the crystal structure of the hydrophilic domain. Biochemistry. 2007;46(9):2275-2288.
doi:10.1021/bi602508x'
apa: 'Sazanov, L. A. (2007). Respiratory complex I: Mechanistic and structural insights
provided by the crystal structure of the hydrophilic domain. Biochemistry.
ACS. https://doi.org/10.1021/bi602508x'
chicago: 'Sazanov, Leonid A. “Respiratory Complex I: Mechanistic and Structural
Insights Provided by the Crystal Structure of the Hydrophilic Domain.” Biochemistry.
ACS, 2007. https://doi.org/10.1021/bi602508x.'
ieee: 'L. A. Sazanov, “Respiratory complex I: Mechanistic and structural insights
provided by the crystal structure of the hydrophilic domain,” Biochemistry,
vol. 46, no. 9. ACS, pp. 2275–2288, 2007.'
ista: 'Sazanov LA. 2007. Respiratory complex I: Mechanistic and structural insights
provided by the crystal structure of the hydrophilic domain. Biochemistry. 46(9),
2275–2288.'
mla: 'Sazanov, Leonid A. “Respiratory Complex I: Mechanistic and Structural Insights
Provided by the Crystal Structure of the Hydrophilic Domain.” Biochemistry,
vol. 46, no. 9, ACS, 2007, pp. 2275–88, doi:10.1021/bi602508x.'
short: L.A. Sazanov, Biochemistry 46 (2007) 2275–2288.
date_created: 2018-12-11T11:54:57Z
date_published: 2007-03-06T00:00:00Z
date_updated: 2021-01-12T06:54:23Z
day: '06'
doi: 10.1021/bi602508x
extern: 1
intvolume: ' 46'
issue: '9'
month: '03'
page: 2275 - 2288
publication: Biochemistry
publication_status: published
publisher: ACS
publist_id: '5118'
quality_controlled: 0
status: public
title: 'Respiratory complex I: Mechanistic and structural insights provided by the
crystal structure of the hydrophilic domain'
type: journal_article
volume: 46
year: '2007'
...
---
_id: '1965'
abstract:
- lang: eng
text: Respiratory complex I (NADH:ubiquinone oxidoreductase) is an L-shaped multisubunit
protein assembly consisting of a hydrophobic membrane arm and a hydrophilic peripheral
arm. It catalyses the transfer of two electrons from NADH to quinone coupled to
the translocation of four protons across the membrane. Although we have solved
recently the crystal structure of the peripheral arm, the structure of the complete
enzyme and the coupling mechanism are not yet known. The membrane domain of Escherichia
coli complex I consists of seven different subunits with total molecular mass
of 258 kDa. It is significantly more stable than the whole enzyme, which allowed
us to obtain well-ordered two-dimensional crystals of the domain, belonging to
the space group p22121. Comparison of the projection map of negatively stained
crystals with previously published low-resolution structures indicated that the
characteristic curved shape of the membrane domain is remarkably well conserved
between bacterial and mitochondrial enzymes, helping us to interpret projection
maps in the context of the intact complex. Two pronounced stain-excluding densities
at the distal end of the membrane domain are likely to represent the two large
antiporter-like subunits NuoL and NuoM. Cryo-electron microscopy on frozen-hydrated
crystals allowed us to calculate a projection map at 8 Å resolution. About 60
transmembrane α-helices, both perpendicular to the membrane plane and tilted,
are present within one membrane domain, which is consistent with secondary structure
predictions. A possible binding site and access channel for quinone are found
at the interface with the peripheral arm. Tentative assignment of individual subunits
to the features of the map has been made. The location of subunits NuoL and NuoM
at substantial distance from the peripheral arm, which contains all the redox
centres of the complex, indicates that conformational changes are likely to play
a role in the mechanism of coupling between electron transfer and proton pumping.
author:
- first_name: Ekaterina
full_name: Baranova, Ekaterina A
last_name: Baranova
- first_name: Peter
full_name: Holt, Peter J
last_name: Holt
- first_name: Leonid A
full_name: Leonid Sazanov
id: 338D39FE-F248-11E8-B48F-1D18A9856A87
last_name: Sazanov
orcid: 0000-0002-0977-7989
citation:
ama: Baranova E, Holt P, Sazanov LA. Projection structure of the membrane domain
of Escherichia coli respiratory Complex I at 8 Å resolution. Journal of Molecular
Biology. 2007;366(1):140-154. doi:10.1016/j.jmb.2006.11.026
apa: Baranova, E., Holt, P., & Sazanov, L. A. (2007). Projection structure of
the membrane domain of Escherichia coli respiratory Complex I at 8 Å resolution.
Journal of Molecular Biology. Elsevier. https://doi.org/10.1016/j.jmb.2006.11.026
chicago: Baranova, Ekaterina, Peter Holt, and Leonid A Sazanov. “Projection Structure
of the Membrane Domain of Escherichia Coli Respiratory Complex I at 8 Å Resolution.”
Journal of Molecular Biology. Elsevier, 2007. https://doi.org/10.1016/j.jmb.2006.11.026.
ieee: E. Baranova, P. Holt, and L. A. Sazanov, “Projection structure of the membrane
domain of Escherichia coli respiratory Complex I at 8 Å resolution,” Journal
of Molecular Biology, vol. 366, no. 1. Elsevier, pp. 140–154, 2007.
ista: Baranova E, Holt P, Sazanov LA. 2007. Projection structure of the membrane
domain of Escherichia coli respiratory Complex I at 8 Å resolution. Journal of
Molecular Biology. 366(1), 140–154.
mla: Baranova, Ekaterina, et al. “Projection Structure of the Membrane Domain of
Escherichia Coli Respiratory Complex I at 8 Å Resolution.” Journal of Molecular
Biology, vol. 366, no. 1, Elsevier, 2007, pp. 140–54, doi:10.1016/j.jmb.2006.11.026.
short: E. Baranova, P. Holt, L.A. Sazanov, Journal of Molecular Biology 366 (2007)
140–154.
date_created: 2018-12-11T11:54:57Z
date_published: 2007-02-09T00:00:00Z
date_updated: 2021-01-12T06:54:23Z
day: '09'
doi: 10.1016/j.jmb.2006.11.026
extern: 1
intvolume: ' 366'
issue: '1'
month: '02'
page: 140 - 154
publication: Journal of Molecular Biology
publication_status: published
publisher: Elsevier
publist_id: '5119'
quality_controlled: 0
status: public
title: Projection structure of the membrane domain of Escherichia coli respiratory
Complex I at 8 Å resolution
type: journal_article
volume: 366
year: '2007'
...
---
_id: '1969'
abstract:
- lang: eng
text: Respiratory complex I catalyses the transfer of electrons from NADH to quinone
coupled to the translocation of protons across the membrane. The mechanism of
coupling and the structure of the complete enzyme are not known. The membrane
domain of the complex contains three similar antiporter-like subunits NuoL/M/N,
probably involved in proton pumping. We have previously shown that subunits NuoL/M
can be removed from the rest of the complex, suggesting their location at the
distal end of the membrane domain. Here, using electron microscopy and single
particle analysis, we show that subunits NuoL and M jointly occupy a distal half
of the membrane domain, separated by about 10 nm from the interface with the peripheral
arm. This indicates that coupling mechanism of complex I is likely to involve
long range conformational changes.
author:
- first_name: Ekaterina
full_name: Baranova, Ekaterina A
last_name: Baranova
- first_name: David
full_name: Morgan, David J
last_name: Morgan
- first_name: Leonid A
full_name: Leonid Sazanov
id: 338D39FE-F248-11E8-B48F-1D18A9856A87
last_name: Sazanov
orcid: 0000-0002-0977-7989
citation:
ama: Baranova E, Morgan D, Sazanov LA. Single particle analysis confirms distal
location of subunits NuoL and NuoM in Escherichia coli complex I. Journal of
Structural Biology. 2007;159(2 SPEC. ISS.):238-242. doi:10.1016/j.jsb.2007.01.009
apa: Baranova, E., Morgan, D., & Sazanov, L. A. (2007). Single particle analysis
confirms distal location of subunits NuoL and NuoM in Escherichia coli complex
I. Journal of Structural Biology. Academic Press. https://doi.org/10.1016/j.jsb.2007.01.009
chicago: Baranova, Ekaterina, David Morgan, and Leonid A Sazanov. “Single Particle
Analysis Confirms Distal Location of Subunits NuoL and NuoM in Escherichia Coli
Complex I.” Journal of Structural Biology. Academic Press, 2007. https://doi.org/10.1016/j.jsb.2007.01.009.
ieee: E. Baranova, D. Morgan, and L. A. Sazanov, “Single particle analysis confirms
distal location of subunits NuoL and NuoM in Escherichia coli complex I,” Journal
of Structural Biology, vol. 159, no. 2 SPEC. ISS. Academic Press, pp. 238–242,
2007.
ista: Baranova E, Morgan D, Sazanov LA. 2007. Single particle analysis confirms
distal location of subunits NuoL and NuoM in Escherichia coli complex I. Journal
of Structural Biology. 159(2 SPEC. ISS.), 238–242.
mla: Baranova, Ekaterina, et al. “Single Particle Analysis Confirms Distal Location
of Subunits NuoL and NuoM in Escherichia Coli Complex I.” Journal of Structural
Biology, vol. 159, no. 2 SPEC. ISS., Academic Press, 2007, pp. 238–42, doi:10.1016/j.jsb.2007.01.009.
short: E. Baranova, D. Morgan, L.A. Sazanov, Journal of Structural Biology 159 (2007)
238–242.
date_created: 2018-12-11T11:54:58Z
date_published: 2007-08-01T00:00:00Z
date_updated: 2021-01-12T06:54:24Z
day: '01'
doi: 10.1016/j.jsb.2007.01.009
extern: 1
intvolume: ' 159'
issue: 2 SPEC. ISS.
month: '08'
page: 238 - 242
publication: Journal of Structural Biology
publication_status: published
publisher: Academic Press
publist_id: '5117'
quality_controlled: 0
status: public
title: Single particle analysis confirms distal location of subunits NuoL and NuoM
in Escherichia coli complex I
type: journal_article
volume: 159
year: '2007'
...
---
_id: '13424'
abstract:
- lang: eng
text: 'Changing shapes: Metastable spherical aggregates of gold nanoparticles undergo
a one-to-one, thermally induced transformation into heterodimers comprising connected
plate and spherical domains. By controlling the reaction time, it is possible
to isolate a variety of structures differing in the relative sizes of the domains
and in the overall optical properties (see picture).'
article_processing_charge: No
article_type: original
author:
- first_name: Rafal
full_name: Klajn, Rafal
id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
last_name: Klajn
- first_name: Anatoliy O.
full_name: Pinchuk, Anatoliy O.
last_name: Pinchuk
- first_name: George C.
full_name: Schatz, George C.
last_name: Schatz
- first_name: Bartosz A.
full_name: Grzybowski, Bartosz A.
last_name: Grzybowski
citation:
ama: Klajn R, Pinchuk AO, Schatz GC, Grzybowski BA. Synthesis of heterodimeric sphere–prism
nanostructures via metastable gold supraspheres. Angewandte Chemie International
Edition. 2007;46(44):8363-8367. doi:10.1002/anie.200702570
apa: Klajn, R., Pinchuk, A. O., Schatz, G. C., & Grzybowski, B. A. (2007). Synthesis
of heterodimeric sphere–prism nanostructures via metastable gold supraspheres.
Angewandte Chemie International Edition. Wiley. https://doi.org/10.1002/anie.200702570
chicago: Klajn, Rafal, Anatoliy O. Pinchuk, George C. Schatz, and Bartosz A. Grzybowski.
“Synthesis of Heterodimeric Sphere–Prism Nanostructures via Metastable Gold Supraspheres.”
Angewandte Chemie International Edition. Wiley, 2007. https://doi.org/10.1002/anie.200702570.
ieee: R. Klajn, A. O. Pinchuk, G. C. Schatz, and B. A. Grzybowski, “Synthesis of
heterodimeric sphere–prism nanostructures via metastable gold supraspheres,” Angewandte
Chemie International Edition, vol. 46, no. 44. Wiley, pp. 8363–8367, 2007.
ista: Klajn R, Pinchuk AO, Schatz GC, Grzybowski BA. 2007. Synthesis of heterodimeric
sphere–prism nanostructures via metastable gold supraspheres. Angewandte Chemie
International Edition. 46(44), 8363–8367.
mla: Klajn, Rafal, et al. “Synthesis of Heterodimeric Sphere–Prism Nanostructures
via Metastable Gold Supraspheres.” Angewandte Chemie International Edition,
vol. 46, no. 44, Wiley, 2007, pp. 8363–67, doi:10.1002/anie.200702570.
short: R. Klajn, A.O. Pinchuk, G.C. Schatz, B.A. Grzybowski, Angewandte Chemie International
Edition 46 (2007) 8363–8367.
date_created: 2023-08-01T10:31:08Z
date_published: 2007-11-12T00:00:00Z
date_updated: 2023-08-08T11:17:57Z
day: '12'
doi: 10.1002/anie.200702570
extern: '1'
external_id:
pmid:
- '17902083'
intvolume: ' 46'
issue: '44'
keyword:
- General Chemistry
- Catalysis
language:
- iso: eng
month: '11'
oa_version: None
page: 8363-8367
pmid: 1
publication: Angewandte Chemie International Edition
publication_identifier:
eissn:
- 1521-3773
issn:
- 1433-7851
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Synthesis of heterodimeric sphere–prism nanostructures via metastable gold
supraspheres
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 46
year: '2007'
...