---
_id: '230'
abstract:
- lang: eng
text: The Manin conjecture is established for a split singular cubic surface in
ℙ 3, with singularity type D 5.
acknowledgement: "EP/E053262/1\tEngineering and Physical Sciences Research Council"
author:
- first_name: Timothy D
full_name: Timothy Browning
id: 35827D50-F248-11E8-B48F-1D18A9856A87
last_name: Browning
orcid: 0000-0002-8314-0177
- first_name: Ulrich
full_name: Derenthal, Ulrich
last_name: Derenthal
citation:
ama: Browning TD, Derenthal U. Manin’s conjecture for a cubic surface with D 5
singularity. International Mathematics Research Notices. 2009;2009(14):2620-2647.
doi:10.1093/imrn/rnp029
apa: Browning, T. D., & Derenthal, U. (2009). Manin’s conjecture for a cubic
surface with D 5 singularity. International Mathematics Research Notices.
Oxford University Press. https://doi.org/10.1093/imrn/rnp029
chicago: Browning, Timothy D, and Ulrich Derenthal. “Manin’s Conjecture for a Cubic
Surface with D 5 Singularity.” International Mathematics Research Notices.
Oxford University Press, 2009. https://doi.org/10.1093/imrn/rnp029.
ieee: T. D. Browning and U. Derenthal, “Manin’s conjecture for a cubic surface with
D 5 singularity,” International Mathematics Research Notices, vol. 2009,
no. 14. Oxford University Press, pp. 2620–2647, 2009.
ista: Browning TD, Derenthal U. 2009. Manin’s conjecture for a cubic surface with
D 5 singularity. International Mathematics Research Notices. 2009(14), 2620–2647.
mla: Browning, Timothy D., and Ulrich Derenthal. “Manin’s Conjecture for a Cubic
Surface with D 5 Singularity.” International Mathematics Research Notices,
vol. 2009, no. 14, Oxford University Press, 2009, pp. 2620–47, doi:10.1093/imrn/rnp029.
short: T.D. Browning, U. Derenthal, International Mathematics Research Notices 2009
(2009) 2620–2647.
date_created: 2018-12-11T11:45:20Z
date_published: 2009-03-09T00:00:00Z
date_updated: 2021-01-12T06:56:38Z
day: '09'
doi: 10.1093/imrn/rnp029
extern: 1
intvolume: ' 2009'
issue: '14'
month: '03'
page: 2620 - 2647
publication: International Mathematics Research Notices
publication_status: published
publisher: Oxford University Press
publist_id: '7674'
quality_controlled: 0
status: public
title: Manin's conjecture for a cubic surface with D 5 singularity
type: journal_article
volume: 2009
year: '2009'
...
---
_id: '2326'
abstract:
- lang: eng
text: Research into the stability of matter has been one of the most successful
chapters in mathematical physics, and is a prime example of how modern mathematics
can be applied to problems in physics. A unique account of the subject, this book
provides a complete, self-contained description of research on the stability of
matter problem. It introduces the necessary quantum mechanics to mathematicians,
and aspects of functional analysis to physicists. The topics covered include electrodynamics
of classical and quantized fields, Lieb-Thirring and other inequalities in spectral
theory, inequalities in electrostatics, stability of large Coulomb systems, gravitational
stability of stars, basics of equilibrium statistical mechanics, and the existence
of the thermodynamic limit. The book is an up-to-date account for researchers,
and its pedagogical style makes it suitable for advanced undergraduate and graduate
courses in mathematical physics.
article_processing_charge: No
author:
- first_name: Élliott
full_name: Lieb, Élliott
last_name: Lieb
- first_name: Robert
full_name: Seiringer, Robert
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
citation:
ama: Lieb É, Seiringer R. The Stability of Matter in Quantum Mechanics. Cambridge
University Press; 2009.
apa: Lieb, É., & Seiringer, R. (2009). The Stability of Matter in Quantum
Mechanics. Cambridge University Press.
chicago: Lieb, Élliott, and Robert Seiringer. The Stability of Matter in Quantum
Mechanics. Cambridge University Press, 2009.
ieee: É. Lieb and R. Seiringer, The Stability of Matter in Quantum Mechanics.
Cambridge University Press, 2009.
ista: Lieb É, Seiringer R. 2009. The Stability of Matter in Quantum Mechanics, Cambridge
University Press, 310p.
mla: Lieb, Élliott, and Robert Seiringer. The Stability of Matter in Quantum
Mechanics. Cambridge University Press, 2009.
short: É. Lieb, R. Seiringer, The Stability of Matter in Quantum Mechanics, Cambridge
University Press, 2009.
date_created: 2018-12-11T11:57:00Z
date_published: 2009-01-01T00:00:00Z
date_updated: 2021-12-21T15:45:31Z
day: '01'
extern: '1'
language:
- iso: eng
main_file_link:
- url: http://www.cambridge.org/9780521191180
month: '01'
oa_version: None
page: '310'
publication_identifier:
isbn:
- '978-0-521-19118-0 '
publication_status: published
publisher: Cambridge University Press
publist_id: '4601'
quality_controlled: '1'
status: public
title: The Stability of Matter in Quantum Mechanics
type: book
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2009'
...
---
_id: '2330'
alternative_title:
- Contemporary Mathematics
author:
- first_name: Christian
full_name: Hainzl, Christian
last_name: Hainzl
- first_name: Robert
full_name: Robert Seiringer
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
citation:
ama: 'Hainzl C, Seiringer R. A linear criterion for solutions of non-linear equations,
with application to the BCS gap equation. In: Vol 500. American Mathematical Society;
2009:101-104. doi:10.1090/conm/500/09823'
apa: Hainzl, C., & Seiringer, R. (2009). A linear criterion for solutions of
non-linear equations, with application to the BCS gap equation (Vol. 500, pp.
101–104). Presented at the Spectral and Scattering Theory for Quantum Magnetic
Systems, American Mathematical Society. https://doi.org/10.1090/conm/500/09823
chicago: Hainzl, Christian, and Robert Seiringer. “A Linear Criterion for Solutions
of Non-Linear Equations, with Application to the BCS Gap Equation,” 500:101–4.
American Mathematical Society, 2009. https://doi.org/10.1090/conm/500/09823.
ieee: C. Hainzl and R. Seiringer, “A linear criterion for solutions of non-linear
equations, with application to the BCS gap equation,” presented at the Spectral
and Scattering Theory for Quantum Magnetic Systems, 2009, vol. 500, pp. 101–104.
ista: Hainzl C, Seiringer R. 2009. A linear criterion for solutions of non-linear
equations, with application to the BCS gap equation. Spectral and Scattering Theory
for Quantum Magnetic Systems, Contemporary Mathematics, vol. 500, 101–104.
mla: Hainzl, Christian, and Robert Seiringer. A Linear Criterion for Solutions
of Non-Linear Equations, with Application to the BCS Gap Equation. Vol. 500,
American Mathematical Society, 2009, pp. 101–04, doi:10.1090/conm/500/09823.
short: C. Hainzl, R. Seiringer, in:, American Mathematical Society, 2009, pp. 101–104.
conference:
name: Spectral and Scattering Theory for Quantum Magnetic Systems
date_created: 2018-12-11T11:57:02Z
date_published: 2009-01-01T00:00:00Z
date_updated: 2021-01-12T06:56:50Z
day: '01'
doi: 10.1090/conm/500/09823
extern: 1
intvolume: ' 500'
month: '01'
page: 101 - 104
publication_status: published
publisher: American Mathematical Society
publist_id: '4596'
quality_controlled: 0
status: public
title: A linear criterion for solutions of non-linear equations, with application
to the BCS gap equation
type: conference
volume: 500
year: '2009'
...
---
_id: '2384'
abstract:
- lang: eng
text: We prove the Lee-Huang-Yang formula for the ground state energy of the 3D
Bose gas with repulsive interactions described by the exponential function, in
a simultaneous limit of weak coupling and high density. In particular, we show
that the Bogoliubov approximation is exact in an appropriate parameter regime,
as far as the ground state energy is concerned.
author:
- first_name: Alessandro
full_name: Giuliani, Alessandro
last_name: Giuliani
- first_name: Robert
full_name: Robert Seiringer
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
citation:
ama: Giuliani A, Seiringer R. The ground state energy of the weakly interacting
Bose gas at high density. Journal of Statistical Physics. 2009;135(5-6):915-934.
doi:10.1007/s10955-009-9718-0
apa: Giuliani, A., & Seiringer, R. (2009). The ground state energy of the weakly
interacting Bose gas at high density. Journal of Statistical Physics. Springer.
https://doi.org/10.1007/s10955-009-9718-0
chicago: Giuliani, Alessandro, and Robert Seiringer. “The Ground State Energy of
the Weakly Interacting Bose Gas at High Density.” Journal of Statistical Physics.
Springer, 2009. https://doi.org/10.1007/s10955-009-9718-0.
ieee: A. Giuliani and R. Seiringer, “The ground state energy of the weakly interacting
Bose gas at high density,” Journal of Statistical Physics, vol. 135, no.
5–6. Springer, pp. 915–934, 2009.
ista: Giuliani A, Seiringer R. 2009. The ground state energy of the weakly interacting
Bose gas at high density. Journal of Statistical Physics. 135(5–6), 915–934.
mla: Giuliani, Alessandro, and Robert Seiringer. “The Ground State Energy of the
Weakly Interacting Bose Gas at High Density.” Journal of Statistical Physics,
vol. 135, no. 5–6, Springer, 2009, pp. 915–34, doi:10.1007/s10955-009-9718-0.
short: A. Giuliani, R. Seiringer, Journal of Statistical Physics 135 (2009) 915–934.
date_created: 2018-12-11T11:57:21Z
date_published: 2009-06-01T00:00:00Z
date_updated: 2021-01-12T06:57:09Z
day: '01'
doi: 10.1007/s10955-009-9718-0
extern: 1
intvolume: ' 135'
issue: 5-6
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/0811.1166
month: '06'
oa: 1
page: 915 - 934
publication: Journal of Statistical Physics
publication_status: published
publisher: Springer
publist_id: '4542'
quality_controlled: 0
status: public
title: The ground state energy of the weakly interacting Bose gas at high density
type: journal_article
volume: 135
year: '2009'
...
---
_id: '2385'
abstract:
- lang: eng
text: We consider an ultracold rotating Bose gas in a harmonic trap close to the
critical angular velocity, so that the system can be considered to be confined
to the lowest Landau level. With this assumption we prove that the Gross-Pitaevskii
energy functional accurately describes the ground-state energy of the corresponding
N -body Hamiltonian with contact interaction provided the total angular momentum
L is much less than N2. While the Gross-Pitaevskii energy is always an obvious
variational upper bound to the ground-state energy, a more refined analysis is
needed to establish it as an exact lower bound. We also discuss the question of
Bose-Einstein condensation in the parameter range considered. Coherent states
together with inequalities in spaces of analytic functions are the main technical
tools.
author:
- first_name: Élliott
full_name: Lieb, Élliott H
last_name: Lieb
- first_name: Robert
full_name: Robert Seiringer
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
- first_name: Jakob
full_name: Yngvason, Jakob
last_name: Yngvason
citation:
ama: 'Lieb É, Seiringer R, Yngvason J. Yrast line of a rapidly rotating Bose gas:
Gross-Pitaevskii regime. Physical Review A - Atomic, Molecular, and Optical
Physics. 2009;79(6). doi:10.1103/PhysRevA.79.063626'
apa: 'Lieb, É., Seiringer, R., & Yngvason, J. (2009). Yrast line of a rapidly
rotating Bose gas: Gross-Pitaevskii regime. Physical Review A - Atomic, Molecular,
and Optical Physics. American Physical Society. https://doi.org/10.1103/PhysRevA.79.063626'
chicago: 'Lieb, Élliott, Robert Seiringer, and Jakob Yngvason. “Yrast Line of a
Rapidly Rotating Bose Gas: Gross-Pitaevskii Regime.” Physical Review A - Atomic,
Molecular, and Optical Physics. American Physical Society, 2009. https://doi.org/10.1103/PhysRevA.79.063626.'
ieee: 'É. Lieb, R. Seiringer, and J. Yngvason, “Yrast line of a rapidly rotating
Bose gas: Gross-Pitaevskii regime,” Physical Review A - Atomic, Molecular,
and Optical Physics, vol. 79, no. 6. American Physical Society, 2009.'
ista: 'Lieb É, Seiringer R, Yngvason J. 2009. Yrast line of a rapidly rotating Bose
gas: Gross-Pitaevskii regime. Physical Review A - Atomic, Molecular, and Optical
Physics. 79(6).'
mla: 'Lieb, Élliott, et al. “Yrast Line of a Rapidly Rotating Bose Gas: Gross-Pitaevskii
Regime.” Physical Review A - Atomic, Molecular, and Optical Physics, vol.
79, no. 6, American Physical Society, 2009, doi:10.1103/PhysRevA.79.063626.'
short: É. Lieb, R. Seiringer, J. Yngvason, Physical Review A - Atomic, Molecular,
and Optical Physics 79 (2009).
date_created: 2018-12-11T11:57:22Z
date_published: 2009-06-24T00:00:00Z
date_updated: 2021-01-12T06:57:09Z
day: '24'
doi: 10.1103/PhysRevA.79.063626
extern: 1
intvolume: ' 79'
issue: '6'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/0904.1750
month: '06'
oa: 1
publication: Physical Review A - Atomic, Molecular, and Optical Physics
publication_status: published
publisher: American Physical Society
publist_id: '4541'
quality_controlled: 0
status: public
title: 'Yrast line of a rapidly rotating Bose gas: Gross-Pitaevskii regime'
type: journal_article
volume: 79
year: '2009'
...
---
_id: '2386'
abstract:
- lang: eng
text: We prove exponential decay of the off-diagonal correlation function in the
two-dimensional homogeneous Bose gas when a2 ρ is small and the temperature T
satisfies T> 4πρ ln | ln (a2 ρ) |. Here, a is the scattering length of the
repulsive interaction potential and ρ is the density. To the leading order in
a2 ρ, this bound agrees with the expected critical temperature for superfluidity.
In the three-dimensional Bose gas, exponential decay is proved when T- Tc (0)
Tc (0) >5 a ρ1/3, where Tc (0) is the critical temperature of the ideal gas.
While this condition is not expected to be sharp, it gives a rigorous upper bound
on the critical temperature for Bose-Einstein condensation.
author:
- first_name: Robert
full_name: Robert Seiringer
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
- first_name: Daniel
full_name: Ueltschi, Daniel
last_name: Ueltschi
citation:
ama: Seiringer R, Ueltschi D. Rigorous upper bound on the critical temperature of
dilute Bose gases. Physical Review B - Condensed Matter and Materials Physics.
2009;80(1). doi:10.1103/PhysRevB.80.014502
apa: Seiringer, R., & Ueltschi, D. (2009). Rigorous upper bound on the critical
temperature of dilute Bose gases. Physical Review B - Condensed Matter and
Materials Physics. American Physical Society. https://doi.org/10.1103/PhysRevB.80.014502
chicago: Seiringer, Robert, and Daniel Ueltschi. “Rigorous Upper Bound on the Critical
Temperature of Dilute Bose Gases.” Physical Review B - Condensed Matter and
Materials Physics. American Physical Society, 2009. https://doi.org/10.1103/PhysRevB.80.014502.
ieee: R. Seiringer and D. Ueltschi, “Rigorous upper bound on the critical temperature
of dilute Bose gases,” Physical Review B - Condensed Matter and Materials Physics,
vol. 80, no. 1. American Physical Society, 2009.
ista: Seiringer R, Ueltschi D. 2009. Rigorous upper bound on the critical temperature
of dilute Bose gases. Physical Review B - Condensed Matter and Materials Physics.
80(1).
mla: Seiringer, Robert, and Daniel Ueltschi. “Rigorous Upper Bound on the Critical
Temperature of Dilute Bose Gases.” Physical Review B - Condensed Matter and
Materials Physics, vol. 80, no. 1, American Physical Society, 2009, doi:10.1103/PhysRevB.80.014502.
short: R. Seiringer, D. Ueltschi, Physical Review B - Condensed Matter and Materials
Physics 80 (2009).
date_created: 2018-12-11T11:57:22Z
date_published: 2009-06-02T00:00:00Z
date_updated: 2021-01-12T06:57:10Z
day: '02'
doi: 10.1103/PhysRevB.80.014502
extern: 1
intvolume: ' 80'
issue: '1'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/0904.0050
month: '06'
oa: 1
publication: Physical Review B - Condensed Matter and Materials Physics
publication_status: published
publisher: American Physical Society
publist_id: '4540'
quality_controlled: 0
status: public
title: Rigorous upper bound on the critical temperature of dilute Bose gases
type: journal_article
volume: 80
year: '2009'
...
---
_id: '2387'
abstract:
- lang: eng
text: We consider a system of trapped spinless bosons interacting with a repulsive
potential and subject to rotation. In the limit of rapid rotation and small scattering
length, we rigorously show that the ground state energy converges to that of a
simplified model Hamiltonian with contact interaction projected onto the Lowest
Landau Level. This effective Hamiltonian models the bosonic analogue of the Fractional
Quantum Hall Effect (FQHE). For a fixed number of particles, we also prove convergence
of states; in particular, in a certain regime we show convergence towards the
bosonic Laughlin wavefunction. This is the first rigorous justification of the
effective FQHE Hamiltonian for rapidly rotating Bose gases. We review previous
results on this effective Hamiltonian and outline open problems.
author:
- first_name: Mathieu
full_name: Lewin, Mathieu
last_name: Lewin
- first_name: Robert
full_name: Robert Seiringer
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
citation:
ama: Lewin M, Seiringer R. Strongly correlated phases in rapidly rotating Bose gases.
Journal of Statistical Physics. 2009;137(5):1040-1062. doi:10.1007/s10955-009-9833-y
apa: Lewin, M., & Seiringer, R. (2009). Strongly correlated phases in rapidly
rotating Bose gases. Journal of Statistical Physics. Springer. https://doi.org/10.1007/s10955-009-9833-y
chicago: Lewin, Mathieu, and Robert Seiringer. “Strongly Correlated Phases in Rapidly
Rotating Bose Gases.” Journal of Statistical Physics. Springer, 2009. https://doi.org/10.1007/s10955-009-9833-y.
ieee: M. Lewin and R. Seiringer, “Strongly correlated phases in rapidly rotating
Bose gases,” Journal of Statistical Physics, vol. 137, no. 5. Springer,
pp. 1040–1062, 2009.
ista: Lewin M, Seiringer R. 2009. Strongly correlated phases in rapidly rotating
Bose gases. Journal of Statistical Physics. 137(5), 1040–1062.
mla: Lewin, Mathieu, and Robert Seiringer. “Strongly Correlated Phases in Rapidly
Rotating Bose Gases.” Journal of Statistical Physics, vol. 137, no. 5,
Springer, 2009, pp. 1040–62, doi:10.1007/s10955-009-9833-y.
short: M. Lewin, R. Seiringer, Journal of Statistical Physics 137 (2009) 1040–1062.
date_created: 2018-12-11T11:57:22Z
date_published: 2009-01-01T00:00:00Z
date_updated: 2021-01-12T06:57:10Z
day: '01'
doi: 10.1007/s10955-009-9833-y
extern: 1
intvolume: ' 137'
issue: '5'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/0906.0741
month: '01'
oa: 1
page: 1040 - 1062
publication: Journal of Statistical Physics
publication_status: published
publisher: Springer
publist_id: '4538'
quality_controlled: 0
status: public
title: Strongly correlated phases in rapidly rotating Bose gases
type: journal_article
volume: 137
year: '2009'
...
---
_id: '2388'
abstract:
- lang: eng
text: This paper provides self-contained proof of a theorem relating probabilistic
coherence of forecasts to their non-domination by rival forecasts with respect
to any proper scoring rule. The theorem recapitulates insights achieved by other
investigators, and clarifies the connection of coherence and proper scoring rules
to Bregman divergence.
author:
- first_name: Joel
full_name: Predd, Joel B
last_name: Predd
- first_name: Robert
full_name: Robert Seiringer
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
- first_name: Élliott
full_name: Lieb, Élliott H
last_name: Lieb
- first_name: Daniel
full_name: Osherson, Daniel N
last_name: Osherson
- first_name: Harold
full_name: Poor, Harold V
last_name: Poor
- first_name: Sanjeev
full_name: Kulkarni, Sanjeev R
last_name: Kulkarni
citation:
ama: Predd J, Seiringer R, Lieb É, Osherson D, Poor H, Kulkarni S. Probabilistic
coherence and proper scoring rules. IEEE Transactions on Information Theory.
2009;55(10):4786-4792. doi:10.1109/TIT.2009.2027573
apa: Predd, J., Seiringer, R., Lieb, É., Osherson, D., Poor, H., & Kulkarni,
S. (2009). Probabilistic coherence and proper scoring rules. IEEE Transactions
on Information Theory. IEEE. https://doi.org/10.1109/TIT.2009.2027573
chicago: Predd, Joel, Robert Seiringer, Élliott Lieb, Daniel Osherson, Harold Poor,
and Sanjeev Kulkarni. “Probabilistic Coherence and Proper Scoring Rules.” IEEE
Transactions on Information Theory. IEEE, 2009. https://doi.org/10.1109/TIT.2009.2027573.
ieee: J. Predd, R. Seiringer, É. Lieb, D. Osherson, H. Poor, and S. Kulkarni, “Probabilistic
coherence and proper scoring rules,” IEEE Transactions on Information Theory,
vol. 55, no. 10. IEEE, pp. 4786–4792, 2009.
ista: Predd J, Seiringer R, Lieb É, Osherson D, Poor H, Kulkarni S. 2009. Probabilistic
coherence and proper scoring rules. IEEE Transactions on Information Theory. 55(10),
4786–4792.
mla: Predd, Joel, et al. “Probabilistic Coherence and Proper Scoring Rules.” IEEE
Transactions on Information Theory, vol. 55, no. 10, IEEE, 2009, pp. 4786–92,
doi:10.1109/TIT.2009.2027573.
short: J. Predd, R. Seiringer, É. Lieb, D. Osherson, H. Poor, S. Kulkarni, IEEE
Transactions on Information Theory 55 (2009) 4786–4792.
date_created: 2018-12-11T11:57:23Z
date_published: 2009-10-01T00:00:00Z
date_updated: 2021-01-12T06:57:11Z
day: '01'
doi: 10.1109/TIT.2009.2027573
extern: 1
intvolume: ' 55'
issue: '10'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/0710.3183
month: '10'
oa: 1
page: 4786 - 4792
publication: IEEE Transactions on Information Theory
publication_status: published
publisher: IEEE
publist_id: '4539'
quality_controlled: 0
status: public
title: Probabilistic coherence and proper scoring rules
type: journal_article
volume: 55
year: '2009'
...
---
_id: '2433'
abstract:
- lang: eng
text: 'Let EMBEDk→d be the following algorithmic problem: Given a finite simplicial
complex K of dimension at most k, does there exist a (piecewise linear) embedding
of K into ℝd? Known results easily imply polynomiality of EMBEDk→2 (k = 1, 2;
the case k = 1, d = 2 is graph planarity) and of EMBEDk→2k for all k ≥ 3 (even
if k is not considered fixed). We show that the celebrated result of Novikov on
the algorithmic unsolvability of recognizing the 5-sphere implies that EMBED d→d
and EMBED(d-1)→d are undecidable for each d ≥ 5. Our main result is NP-hardness
of EMBED2→4 and, more generally, of EMBEDk→d for all k, d with d ≥ 4 and d ≥ k
≥ (2d - 2)/3.'
author:
- first_name: Jiří
full_name: Matoušek, Jiří
last_name: Matoušek
- first_name: Martin
full_name: Martin Tancer
id: 38AC689C-F248-11E8-B48F-1D18A9856A87
last_name: Tancer
orcid: 0000-0002-1191-6714
- first_name: Uli
full_name: Uli Wagner
id: 36690CA2-F248-11E8-B48F-1D18A9856A87
last_name: Wagner
orcid: 0000-0002-1494-0568
citation:
ama: 'Matoušek J, Tancer M, Wagner U. Hardness of embedding simplicial complexes
in ℝd. In: SIAM; 2009:855-864.'
apa: 'Matoušek, J., Tancer, M., & Wagner, U. (2009). Hardness of embedding simplicial
complexes in ℝd (pp. 855–864). Presented at the SODA: Symposium on Discrete Algorithms,
SIAM.'
chicago: Matoušek, Jiří, Martin Tancer, and Uli Wagner. “Hardness of Embedding Simplicial
Complexes in ℝd,” 855–64. SIAM, 2009.
ieee: 'J. Matoušek, M. Tancer, and U. Wagner, “Hardness of embedding simplicial
complexes in ℝd,” presented at the SODA: Symposium on Discrete Algorithms, 2009,
pp. 855–864.'
ista: 'Matoušek J, Tancer M, Wagner U. 2009. Hardness of embedding simplicial complexes
in ℝd. SODA: Symposium on Discrete Algorithms, 855–864.'
mla: Matoušek, Jiří, et al. Hardness of Embedding Simplicial Complexes in ℝd.
SIAM, 2009, pp. 855–64.
short: J. Matoušek, M. Tancer, U. Wagner, in:, SIAM, 2009, pp. 855–864.
conference:
name: 'SODA: Symposium on Discrete Algorithms'
date_created: 2018-12-11T11:57:38Z
date_published: 2009-01-01T00:00:00Z
date_updated: 2021-01-12T06:57:27Z
day: '01'
extern: 1
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/0807.0336
month: '01'
oa: 1
page: 855 - 864
publication_status: published
publisher: SIAM
publist_id: '4476'
quality_controlled: 0
status: public
title: Hardness of embedding simplicial complexes in ℝd
type: conference
year: '2009'
...
---
_id: '2434'
abstract:
- lang: eng
text: For a planar point set we consider the graph whose vertices are the crossing-free
straight-line spanning trees of the point set, and two such spanning trees are
adjacent if their union is crossing-free. An upper bound on the diameter of this
graph implies an upper bound on the diameter of the flip graph of pseudo-triangulations
of the underlying point set. We prove a lower bound of Ω(logn/loglogn) for the
diameter of the transformation graph of spanning trees on a set of n points in
the plane. This nearly matches the known upper bound of O(logn). If we measure
the diameter in terms of the number of convex layers k of the point set, our lower
bound construction is tight, i.e., the diameter is in Ω(logk) which matches the
known upper bound of O(logk). So far only constant lower bounds were known.
author:
- first_name: Kevin
full_name: Buchin, Kevin
last_name: Buchin
- first_name: Andreas
full_name: Razen, Andreas
last_name: Razen
- first_name: Takeaki
full_name: Uno, Takeaki
last_name: Uno
- first_name: Uli
full_name: Uli Wagner
id: 36690CA2-F248-11E8-B48F-1D18A9856A87
last_name: Wagner
orcid: 0000-0002-1494-0568
citation:
ama: 'Buchin K, Razen A, Uno T, Wagner U. Transforming spanning trees: A lower bound.
Computational Geometry: Theory and Applications. 2009;42(8):724-730. doi:10.1016/j.comgeo.2008.03.005'
apa: 'Buchin, K., Razen, A., Uno, T., & Wagner, U. (2009). Transforming spanning
trees: A lower bound. Computational Geometry: Theory and Applications.
Elsevier. https://doi.org/10.1016/j.comgeo.2008.03.005'
chicago: 'Buchin, Kevin, Andreas Razen, Takeaki Uno, and Uli Wagner. “Transforming
Spanning Trees: A Lower Bound.” Computational Geometry: Theory and Applications.
Elsevier, 2009. https://doi.org/10.1016/j.comgeo.2008.03.005.'
ieee: 'K. Buchin, A. Razen, T. Uno, and U. Wagner, “Transforming spanning trees:
A lower bound,” Computational Geometry: Theory and Applications, vol. 42,
no. 8. Elsevier, pp. 724–730, 2009.'
ista: 'Buchin K, Razen A, Uno T, Wagner U. 2009. Transforming spanning trees: A
lower bound. Computational Geometry: Theory and Applications. 42(8), 724–730.'
mla: 'Buchin, Kevin, et al. “Transforming Spanning Trees: A Lower Bound.” Computational
Geometry: Theory and Applications, vol. 42, no. 8, Elsevier, 2009, pp. 724–30,
doi:10.1016/j.comgeo.2008.03.005.'
short: 'K. Buchin, A. Razen, T. Uno, U. Wagner, Computational Geometry: Theory and
Applications 42 (2009) 724–730.'
date_created: 2018-12-11T11:57:38Z
date_published: 2009-10-01T00:00:00Z
date_updated: 2021-01-12T06:57:28Z
day: '01'
doi: 10.1016/j.comgeo.2008.03.005
extern: 1
intvolume: ' 42'
issue: '8'
month: '10'
page: 724 - 730
publication: 'Computational Geometry: Theory and Applications'
publication_status: published
publisher: Elsevier
publist_id: '4475'
quality_controlled: 0
status: public
title: 'Transforming spanning trees: A lower bound'
type: journal_article
volume: 42
year: '2009'
...
---
_id: '2498'
abstract:
- lang: eng
text: Activation of G protein-gated inwardly-rectifying K+ (GIRK or Kir3) channels
by metabotropic gamma-aminobutyric acid (B) (GABAB) receptors is an essential
signalling pathway controlling neuronal excitability and synaptic transmission
in the brain. To investigate the relationship between GIRK channel subunits and
GABAB receptors in cerebellar Purkinje cells at post- and pre-synaptic sites,
we used biochemical, functional and immunohistochemical techniques. Co-immunoprecipitation
analysis demonstrated that GIRK subunits are co-assembled with GABAB receptors
in the cerebellum. Immunoelectron microscopy showed that the subunit composition
of GIRK channels in Purkinje cell spines is compartment-dependent. Thus, at extrasynaptic
sites GIRK channels are formed by GIRK1/GIRK2/GIRK3, post-synaptic densities contain
GIRK2/GIRK3 and dendritic shafts contain GIRK1/GIRK3. The post-synaptic association
of GIRK subunits with GABAB receptors in Purkinje cells is supported by the subcellular
regulation of the ion channel and the receptor in mutant mice. At pre-synaptic
sites, GIRK channels localized to parallel fibre terminals are formed by GIRK1/GIRK2/GIRK3
and co-localize with GABAB receptors. Consistent with this morphological evidence
we demonstrate their functional interaction at axon terminals in the cerebellum
by showing that GIRK channels play a role in the inhibition of glutamate release
by GABAB receptors. The association of GIRK channels and GABA B receptors with
excitatory synapses at both post- and pre-synaptic sites indicates their intimate
involvement in the modulation of glutamatergic neurotransmission in the cerebellum.
author:
- first_name: Laura
full_name: Fernández-Alacid, Laura
last_name: Fernández Alacid
- first_name: Carolina
full_name: Aguado, Carolina
last_name: Aguado
- first_name: Francisco
full_name: Ciruela, Francisco
last_name: Ciruela
- first_name: Ricardo
full_name: Martín, Ricardo J
last_name: Martín
- first_name: José
full_name: Colón, José
last_name: Colón
- first_name: María
full_name: Cabañero, María José
last_name: Cabañero
- first_name: Martin
full_name: Gassmann, Martin
last_name: Gassmann
- first_name: Masahiko
full_name: Watanabe, Masahiko
last_name: Watanabe
- first_name: Ryuichi
full_name: Ryuichi Shigemoto
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Kevin
full_name: Wickman, Kevin D
last_name: Wickman
- first_name: Bernhard
full_name: Bettler, Bernhard
last_name: Bettler
- first_name: José
full_name: Sánchez-Prieto, José
last_name: Sánchez Prieto
- first_name: Rafael
full_name: Luján, Rafael
last_name: Luján
citation:
ama: Fernández Alacid L, Aguado C, Ciruela F, et al. Subcellular compartment-specific
molecular diversity of pre- and post-synaptic GABAB-activated GIRK channels in
Purkinje cells. Journal of Neurochemistry. 2009;110(4):1363-1376. doi:10.1111/j.1471-4159.2009.06229.x
apa: Fernández Alacid, L., Aguado, C., Ciruela, F., Martín, R., Colón, J., Cabañero,
M., … Luján, R. (2009). Subcellular compartment-specific molecular diversity
of pre- and post-synaptic GABAB-activated GIRK channels in Purkinje cells. Journal
of Neurochemistry. Wiley-Blackwell. https://doi.org/10.1111/j.1471-4159.2009.06229.x
chicago: Fernández Alacid, Laura, Carolina Aguado, Francisco Ciruela, Ricardo Martín,
José Colón, María Cabañero, Martin Gassmann, et al. “ Subcellular Compartment-Specific
Molecular Diversity of Pre- and Post-Synaptic GABAB-Activated GIRK Channels in
Purkinje Cells.” Journal of Neurochemistry. Wiley-Blackwell, 2009. https://doi.org/10.1111/j.1471-4159.2009.06229.x.
ieee: L. Fernández Alacid et al., “ Subcellular compartment-specific molecular
diversity of pre- and post-synaptic GABAB-activated GIRK channels in Purkinje
cells,” Journal of Neurochemistry, vol. 110, no. 4. Wiley-Blackwell, pp.
1363–1376, 2009.
ista: Fernández Alacid L, Aguado C, Ciruela F, Martín R, Colón J, Cabañero M, Gassmann
M, Watanabe M, Shigemoto R, Wickman K, Bettler B, Sánchez Prieto J, Luján R. 2009. Subcellular
compartment-specific molecular diversity of pre- and post-synaptic GABAB-activated
GIRK channels in Purkinje cells. Journal of Neurochemistry. 110(4), 1363–1376.
mla: Fernández Alacid, Laura, et al. “ Subcellular Compartment-Specific Molecular
Diversity of Pre- and Post-Synaptic GABAB-Activated GIRK Channels in Purkinje
Cells.” Journal of Neurochemistry, vol. 110, no. 4, Wiley-Blackwell, 2009,
pp. 1363–76, doi:10.1111/j.1471-4159.2009.06229.x.
short: L. Fernández Alacid, C. Aguado, F. Ciruela, R. Martín, J. Colón, M. Cabañero,
M. Gassmann, M. Watanabe, R. Shigemoto, K. Wickman, B. Bettler, J. Sánchez Prieto,
R. Luján, Journal of Neurochemistry 110 (2009) 1363–1376.
date_created: 2018-12-11T11:58:01Z
date_published: 2009-08-01T00:00:00Z
date_updated: 2021-01-12T06:57:50Z
day: '01'
doi: 10.1111/j.1471-4159.2009.06229.x
extern: 1
intvolume: ' 110'
issue: '4'
month: '08'
page: 1363 - 1376
publication: Journal of Neurochemistry
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4403'
quality_controlled: 0
status: public
title: ' Subcellular compartment-specific molecular diversity of pre- and post-synaptic
GABAB-activated GIRK channels in Purkinje cells'
type: journal_article
volume: 110
year: '2009'
...
---
_id: '2499'
abstract:
- lang: eng
text: G protein-coupled receptors (GPCRs) have critical functions in intercellular
communication. Although a wide range of different receptors have been identified
in the same cells, the mechanism by which signals are integrated remains elusive.
The ability of GPCRs to form dimers or larger hetero-oligomers is thought to generate
such signal integration. We examined the molecular mechanisms responsible for
the GABAB receptor-mediated potentiation of the mGlu receptor signalling reported
in Purkinje neurons. We showed that this effect does not require a physical interaction
between both receptors. Instead, it is the result of a more general mechanism
in which the βγ subunits produced by the Gi-coupled GABAB receptor enhance the
mGlu-mediated Gq response. Most importantly, this mechanism could be generally
applied to other pairs of Gi- and Gq-coupled receptors and the signal integration
varied depending on the time delay between activation of each receptor. Such a
mechanism helps explain specific properties of cells expressing two different
Gi- and Gq-coupled receptors activated by a single transmitter, or properties
of GPCRs naturally coupled to both types of the G protein.
author:
- first_name: Marie
full_name: Rives, Marie L
last_name: Rives
- first_name: Claire
full_name: Vol, Claire
last_name: Vol
- first_name: Yugo
full_name: Fukazawa, Yugo
last_name: Fukazawa
- first_name: Norbert
full_name: Tinel, Norbert
last_name: Tinel
- first_name: Eric
full_name: Trinquet, Eric
last_name: Trinquet
- first_name: Mohammed
full_name: Ayoub, Mohammed A
last_name: Ayoub
- first_name: Ryuichi
full_name: Ryuichi Shigemoto
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Jean
full_name: Pin, Jean-Philippe
last_name: Pin
- first_name: Laurent
full_name: Prezèau, Laurent
last_name: Prezèau
citation:
ama: Rives M, Vol C, Fukazawa Y, et al. Crosstalk between GABAB and mGlu1a receptors
reveals new insight into GPCR signal integration. EMBO Journal. 2009;28(15):2195-2208.
doi:10.1038/emboj.2009.177
apa: Rives, M., Vol, C., Fukazawa, Y., Tinel, N., Trinquet, E., Ayoub, M., … Prezèau,
L. (2009). Crosstalk between GABAB and mGlu1a receptors reveals new insight into
GPCR signal integration. EMBO Journal. Wiley-Blackwell. https://doi.org/10.1038/emboj.2009.177
chicago: Rives, Marie, Claire Vol, Yugo Fukazawa, Norbert Tinel, Eric Trinquet,
Mohammed Ayoub, Ryuichi Shigemoto, Jean Pin, and Laurent Prezèau. “Crosstalk between
GABAB and MGlu1a Receptors Reveals New Insight into GPCR Signal Integration.”
EMBO Journal. Wiley-Blackwell, 2009. https://doi.org/10.1038/emboj.2009.177.
ieee: M. Rives et al., “Crosstalk between GABAB and mGlu1a receptors reveals
new insight into GPCR signal integration,” EMBO Journal, vol. 28, no. 15.
Wiley-Blackwell, pp. 2195–2208, 2009.
ista: Rives M, Vol C, Fukazawa Y, Tinel N, Trinquet E, Ayoub M, Shigemoto R, Pin
J, Prezèau L. 2009. Crosstalk between GABAB and mGlu1a receptors reveals new insight
into GPCR signal integration. EMBO Journal. 28(15), 2195–2208.
mla: Rives, Marie, et al. “Crosstalk between GABAB and MGlu1a Receptors Reveals
New Insight into GPCR Signal Integration.” EMBO Journal, vol. 28, no. 15,
Wiley-Blackwell, 2009, pp. 2195–208, doi:10.1038/emboj.2009.177.
short: M. Rives, C. Vol, Y. Fukazawa, N. Tinel, E. Trinquet, M. Ayoub, R. Shigemoto,
J. Pin, L. Prezèau, EMBO Journal 28 (2009) 2195–2208.
date_created: 2018-12-11T11:58:01Z
date_published: 2009-08-15T00:00:00Z
date_updated: 2021-01-12T06:57:51Z
day: '15'
doi: 10.1038/emboj.2009.177
extern: 1
intvolume: ' 28'
issue: '15'
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726695/
month: '08'
oa: 1
page: 2195 - 2208
publication: EMBO Journal
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4402'
quality_controlled: 0
status: public
title: Crosstalk between GABAB and mGlu1a receptors reveals new insight into GPCR
signal integration
type: journal_article
volume: 28
year: '2009'
...
---
_id: '2500'
abstract:
- lang: eng
text: 'To examine the intrasynaptic arrangement of postsynaptic receptors in relation
to the functional role of the synapse,we quantitatively analyzed the two-dimensional
distribution of AMPA and NMDA receptors (AMPARs and NMDARs, respectively) using
SDS-digested freeze-fracture replica labeling (SDS-FRL) and assessed the implication
of distribution differences on the postsynaptic responses by simulation. In the
dorsal lateral geniculate nucleus, corticogeniculate (CG) synapses were twice
as large as retinogeniculate (RG) synapses but expressed similar numbers of AMPARs.
Two-dimensional views of replicas revealed that AMPARs form microclusters in both
synapses to a similar extent, resulting in larger AMPAR-lacking areas in the CG
synapses. Despite the broad difference in the AMPAR distribution within a synapse,
our simulations based on the actual receptor distributions suggested that the
AMPAR quantal response at individual RG synapses is only slightly larger in amplitude,
less variable, and faster in kinetics than that at CG synapses having a similar
number of the receptors. NMDARs at the CG synapses were expressed twice as many
as those in the RG synapses. Electrophysiological recordings confirmed a larger
contribution of NMDAR relative to AMPAR-mediated responses in CG synapses. We
conclude that synapse size and the density and distribution of receptors have
minor influences on quantal responses and that the number of receptors acts as
a predominant postsynaptic determinant of the synaptic strength mediated by both
the AMPARs and NMDARs. '
author:
- first_name: Etsuko
full_name: Tarusawa, Etsuko
last_name: Tarusawa
- first_name: Ko
full_name: Matsui, Ko
last_name: Matsui
- first_name: Timotheus
full_name: Budisantoso, Timotheus
last_name: Budisantoso
- first_name: Elek
full_name: Molnár, Elek
last_name: Molnár
- first_name: Masahiko
full_name: Watanabe, Masahiko
last_name: Watanabe
- first_name: Minoru
full_name: Matsui, Minoru
last_name: Matsui
- first_name: Yugo
full_name: Fukazawa, Yugo
last_name: Fukazawa
- first_name: Ryuichi
full_name: Ryuichi Shigemoto
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
citation:
ama: Tarusawa E, Matsui K, Budisantoso T, et al. Input-specific intrasynaptic arrangements
of ionotropic glutamate receptors and their impact on postsynaptic responses.
Journal of Neuroscience. 2009;29(41):12896-12908. doi:10.1523/JNEUROSCI.6160-08.2009
apa: Tarusawa, E., Matsui, K., Budisantoso, T., Molnár, E., Watanabe, M., Matsui,
M., … Shigemoto, R. (2009). Input-specific intrasynaptic arrangements of ionotropic
glutamate receptors and their impact on postsynaptic responses. Journal of
Neuroscience. Society for Neuroscience. https://doi.org/10.1523/JNEUROSCI.6160-08.2009
chicago: Tarusawa, Etsuko, Ko Matsui, Timotheus Budisantoso, Elek Molnár, Masahiko
Watanabe, Minoru Matsui, Yugo Fukazawa, and Ryuichi Shigemoto. “Input-Specific
Intrasynaptic Arrangements of Ionotropic Glutamate Receptors and Their Impact
on Postsynaptic Responses.” Journal of Neuroscience. Society for Neuroscience,
2009. https://doi.org/10.1523/JNEUROSCI.6160-08.2009.
ieee: E. Tarusawa et al., “Input-specific intrasynaptic arrangements of ionotropic
glutamate receptors and their impact on postsynaptic responses,” Journal of
Neuroscience, vol. 29, no. 41. Society for Neuroscience, pp. 12896–12908,
2009.
ista: Tarusawa E, Matsui K, Budisantoso T, Molnár E, Watanabe M, Matsui M, Fukazawa
Y, Shigemoto R. 2009. Input-specific intrasynaptic arrangements of ionotropic
glutamate receptors and their impact on postsynaptic responses. Journal of Neuroscience.
29(41), 12896–12908.
mla: Tarusawa, Etsuko, et al. “Input-Specific Intrasynaptic Arrangements of Ionotropic
Glutamate Receptors and Their Impact on Postsynaptic Responses.” Journal of
Neuroscience, vol. 29, no. 41, Society for Neuroscience, 2009, pp. 12896–908,
doi:10.1523/JNEUROSCI.6160-08.2009.
short: E. Tarusawa, K. Matsui, T. Budisantoso, E. Molnár, M. Watanabe, M. Matsui,
Y. Fukazawa, R. Shigemoto, Journal of Neuroscience 29 (2009) 12896–12908.
date_created: 2018-12-11T11:58:02Z
date_published: 2009-10-14T00:00:00Z
date_updated: 2021-01-12T06:57:52Z
day: '14'
doi: 10.1523/JNEUROSCI.6160-08.2009
extern: 1
intvolume: ' 29'
issue: '41'
month: '10'
page: 12896 - 12908
publication: Journal of Neuroscience
publication_status: published
publisher: Society for Neuroscience
publist_id: '4401'
quality_controlled: 0
status: public
title: Input-specific intrasynaptic arrangements of ionotropic glutamate receptors
and their impact on postsynaptic responses
type: journal_article
volume: 29
year: '2009'
...
---
_id: '2501'
abstract:
- lang: eng
text: The brain-specific immediate early gene Arc/Arg3.1 is induced in response
to a variety of stimuli, including sensory and behavior-linked neural activity.
Here we report the generation of transgenic mice, termed TgArc/Arg3.1-d4EGFP,
expressing a 4-h half-life form of enhanced green fluorescent protein (d4EGFP)
under the control of the Arc/Arg3.1 promoter. We show that d4EGFP-mediated fluorescence
faithfully reports Arc/Arg3.1 induction in response to physiological, pathological
and pharmacological stimuli, and that this fluorescence permits electrical recording
from activated neurons in the live mouse. Moreover, the fluorescent Arc/Arg3.1
indicator revealed activity changes in circumscribed brain areas in distinct modes
of stress and in a mouse model of Alzheimer's disease. These findings identify
the TgArc/Arg3.1-d4EGFP mouse as a versatile tool to monitor Arc/Arg3.1 induction
in neural circuits, both in vitro and in vivo.
author:
- first_name: Valery
full_name: Grinevich, Valery V
last_name: Grinevich
- first_name: Alexander
full_name: Kolleker, Alexander
last_name: Kolleker
- first_name: Marina
full_name: Eliava, Marina I
last_name: Eliava
- first_name: Naoki
full_name: Takada, Naoki
last_name: Takada
- first_name: Hiroshi
full_name: Takuma, Hiroshi
last_name: Takuma
- first_name: Yugo
full_name: Fukazawa, Yugo
last_name: Fukazawa
- first_name: Ryuichi
full_name: Ryuichi Shigemoto
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Dietmar
full_name: Kuhl, Dietmar
last_name: Kuhl
- first_name: Jack
full_name: Waters, Jack
last_name: Waters
- first_name: Peter
full_name: Seeburg, Peter H
last_name: Seeburg
- first_name: Pavel
full_name: Osten, Pavel
last_name: Osten
citation:
ama: 'Grinevich V, Kolleker A, Eliava M, et al. Fluorescent Arc/Arg3.1 indicator
mice: A versatile tool to study brain activity changes in vitro and in vivo. Journal
of Neuroscience Methods. 2009;184(1):25-36. doi:10.1016/j.jneumeth.2009.07.015'
apa: 'Grinevich, V., Kolleker, A., Eliava, M., Takada, N., Takuma, H., Fukazawa,
Y., … Osten, P. (2009). Fluorescent Arc/Arg3.1 indicator mice: A versatile tool
to study brain activity changes in vitro and in vivo. Journal of Neuroscience
Methods. Elsevier. https://doi.org/10.1016/j.jneumeth.2009.07.015'
chicago: 'Grinevich, Valery, Alexander Kolleker, Marina Eliava, Naoki Takada, Hiroshi
Takuma, Yugo Fukazawa, Ryuichi Shigemoto, et al. “Fluorescent Arc/Arg3.1 Indicator
Mice: A Versatile Tool to Study Brain Activity Changes in Vitro and in Vivo.”
Journal of Neuroscience Methods. Elsevier, 2009. https://doi.org/10.1016/j.jneumeth.2009.07.015.'
ieee: 'V. Grinevich et al., “Fluorescent Arc/Arg3.1 indicator mice: A versatile
tool to study brain activity changes in vitro and in vivo,” Journal of Neuroscience
Methods, vol. 184, no. 1. Elsevier, pp. 25–36, 2009.'
ista: 'Grinevich V, Kolleker A, Eliava M, Takada N, Takuma H, Fukazawa Y, Shigemoto
R, Kuhl D, Waters J, Seeburg P, Osten P. 2009. Fluorescent Arc/Arg3.1 indicator
mice: A versatile tool to study brain activity changes in vitro and in vivo. Journal
of Neuroscience Methods. 184(1), 25–36.'
mla: 'Grinevich, Valery, et al. “Fluorescent Arc/Arg3.1 Indicator Mice: A Versatile
Tool to Study Brain Activity Changes in Vitro and in Vivo.” Journal of Neuroscience
Methods, vol. 184, no. 1, Elsevier, 2009, pp. 25–36, doi:10.1016/j.jneumeth.2009.07.015.'
short: V. Grinevich, A. Kolleker, M. Eliava, N. Takada, H. Takuma, Y. Fukazawa,
R. Shigemoto, D. Kuhl, J. Waters, P. Seeburg, P. Osten, Journal of Neuroscience
Methods 184 (2009) 25–36.
date_created: 2018-12-11T11:58:02Z
date_published: 2009-10-30T00:00:00Z
date_updated: 2021-01-12T06:57:52Z
day: '30'
doi: 10.1016/j.jneumeth.2009.07.015
extern: 1
intvolume: ' 184'
issue: '1'
month: '10'
page: 25 - 36
publication: Journal of Neuroscience Methods
publication_status: published
publisher: Elsevier
publist_id: '4400'
quality_controlled: 0
status: public
title: 'Fluorescent Arc/Arg3.1 indicator mice: A versatile tool to study brain activity
changes in vitro and in vivo'
type: journal_article
volume: 184
year: '2009'
...
---
_id: '2502'
abstract:
- lang: eng
text: In order to acquire phase-contrast images with adequate contrast, conventional
TEM requires large amount of defocus. Increasing the defocus improves the low-frequency
components but attenuates the high-frequency ones. On the other hand, Zernike
phase-contrast TEM (ZPC-TEM) can recover low-frequency components without losing
the high-frequency ones under in-focus conditions. ZPC-TEM however, has another
problem, especially in imaging of complex biological specimens such as cells and
tissues; strong halos appear around specimen structures, and these halos hinder
the interpretation of images. Due to this problem, the application of ZPC-TEM
has been restricted to imaging of smaller particles. In order to improve the halo
appearance, we fabricated a new quarter-wave thin film phase-plate with a smaller
central hole and tested it on vitreous biological specimens. ZPC-TEM with the
new plate could successfully visualize, in in-focus images, the intracellular
fine features of cultured cells and brain tissues. This result indicates that
reduction of the central hole diameter makes ZPC-TEM applicable on size scales
ranging from protein particles to tissue sections. The application of ZPC-TEM
to vitreous biological specimens will be a powerful method to advance the new
field of imaging science for ultrastructures in close-to-physiological state.
author:
- first_name: Yoshiyuki
full_name: Fukuda, Yoshiyuki
last_name: Fukuda
- first_name: Yugo
full_name: Fukazawa, Yugo
last_name: Fukazawa
- first_name: Radostin
full_name: Danev, Radostin S
last_name: Danev
- first_name: Ryuichi
full_name: Ryuichi Shigemoto
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Kuniaki
full_name: Nagayama, Kuniaki
last_name: Nagayama
citation:
ama: Fukuda Y, Fukazawa Y, Danev R, Shigemoto R, Nagayama K. Tuning of the Zernike
phase-plate for visualization of detailed ultrastructure in complex biological
specimens. Journal of Structural Biology. 2009;168(3):476-484. doi:10.1016/j.jsb.2009.08.011
apa: Fukuda, Y., Fukazawa, Y., Danev, R., Shigemoto, R., & Nagayama, K. (2009).
Tuning of the Zernike phase-plate for visualization of detailed ultrastructure
in complex biological specimens. Journal of Structural Biology. Academic
Press. https://doi.org/10.1016/j.jsb.2009.08.011
chicago: Fukuda, Yoshiyuki, Yugo Fukazawa, Radostin Danev, Ryuichi Shigemoto, and
Kuniaki Nagayama. “Tuning of the Zernike Phase-Plate for Visualization of Detailed
Ultrastructure in Complex Biological Specimens.” Journal of Structural Biology.
Academic Press, 2009. https://doi.org/10.1016/j.jsb.2009.08.011.
ieee: Y. Fukuda, Y. Fukazawa, R. Danev, R. Shigemoto, and K. Nagayama, “Tuning of
the Zernike phase-plate for visualization of detailed ultrastructure in complex
biological specimens,” Journal of Structural Biology, vol. 168, no. 3.
Academic Press, pp. 476–484, 2009.
ista: Fukuda Y, Fukazawa Y, Danev R, Shigemoto R, Nagayama K. 2009. Tuning of the
Zernike phase-plate for visualization of detailed ultrastructure in complex biological
specimens. Journal of Structural Biology. 168(3), 476–484.
mla: Fukuda, Yoshiyuki, et al. “Tuning of the Zernike Phase-Plate for Visualization
of Detailed Ultrastructure in Complex Biological Specimens.” Journal of Structural
Biology, vol. 168, no. 3, Academic Press, 2009, pp. 476–84, doi:10.1016/j.jsb.2009.08.011.
short: Y. Fukuda, Y. Fukazawa, R. Danev, R. Shigemoto, K. Nagayama, Journal of Structural
Biology 168 (2009) 476–484.
date_created: 2018-12-11T11:58:03Z
date_published: 2009-12-01T00:00:00Z
date_updated: 2021-01-12T06:57:52Z
day: '01'
doi: 10.1016/j.jsb.2009.08.011
extern: 1
intvolume: ' 168'
issue: '3'
month: '12'
page: 476 - 484
publication: Journal of Structural Biology
publication_status: published
publisher: Academic Press
publist_id: '4399'
quality_controlled: 0
status: public
title: Tuning of the Zernike phase-plate for visualization of detailed ultrastructure
in complex biological specimens
type: journal_article
volume: 168
year: '2009'
...
---
_id: '2680'
abstract:
- lang: eng
text: 'GABA B receptor subtypes are based on the subunit isoforms GABA B1a and GABA
B1b, which associate with GABA B2 subunits to form pharmacologically indistinguishable
GABA B(1a,2) and GABA B(1b,2) receptors. Studies with mice selectively expressing
GABA B1a or GABA B1b subunits revealed that GABA B(1a,2) receptors are more abundant
than GABA B(1b,2) receptors at glutamatergic terminals. Accordingly, it was found
that GABA B(1a,2) receptors are more efficient than GABA B(1b,2) receptors in
inhibiting glutamate release when maximally activated by exogenous application
of the agonist baclofen. Here, we used a combination of genetic, ultrastructural
and electrophysiological approaches to analyze to what extent GABA B(1a,2) and
GABA B(1b,2) receptors inhibit glutamate release in response to physiological
activation. We first show that at hippocampal mossy fiber (MF)-CA3 pyramidal neuron
synapses more GABA B1a than GABA B1b protein is present at presynaptic sites,
consistent with the findings at other glutamatergic synapses. In the presence
of baclofen at concentrations ≥1 μM, both GABA B(1a,2) and GABA B(1b,2) receptors
contribute to presynaptic inhibition of glutamate release. However, at lower concentrations
of baclofen, selectively GABA B(1a,2) receptors contribute to presynaptic inhibition.
Remarkably, exclusively GABA B(1a,2) receptors inhibit glutamate release in response
to synaptically released GABA. Specifically, we demonstrate that selectively GABA
B(1a,2) receptors mediate heterosynaptic depression of MF transmission, a physiological
phenomenon involving transsynaptic inhibition of glutamate release via presynaptic
GABA B receptors. Our data demonstrate that the difference in GABA B1a and GABA
B1b protein levels at MF terminals is sufficient to produce a strictly GABA B1a-specific
effect under physiological conditions. This consolidates that the differential
subcellular localization of the GABA B1a and GABA B1b proteins is of regulatory
relevance. '
author:
- first_name: Nicole
full_name: Guetg, Nicole
last_name: Guetg
- first_name: Riad
full_name: Seddik, Riad
last_name: Seddik
- first_name: Réjan
full_name: Vigot, Réjan
last_name: Vigot
- first_name: Rostislav
full_name: Tureček, Rostislav
last_name: Tureček
- first_name: Martin
full_name: Gassmann, Martin
last_name: Gassmann
- first_name: Kaspar
full_name: Vogt, Kaspar E
last_name: Vogt
- first_name: Hans
full_name: Bräuner-Osborne, Hans
last_name: Bräuner Osborne
- first_name: Ryuichi
full_name: Ryuichi Shigemoto
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Oliver
full_name: Kretz, Oliver
last_name: Kretz
- first_name: Michael
full_name: Frotscher, Michael
last_name: Frotscher
- first_name: Ákos
full_name: Kulik, Ákos
last_name: Kulik
- first_name: Bernhard
full_name: Bettler, Bernhard
last_name: Bettler
citation:
ama: Guetg N, Seddik R, Vigot R, et al. The GABA B1a isoform mediates heterosynaptic
depression at hippocampal mossy fiber synapses. Journal of Neuroscience.
2009;29(5):1414-1423. doi:10.1523/JNEUROSCI.3697-08.2009
apa: Guetg, N., Seddik, R., Vigot, R., Tureček, R., Gassmann, M., Vogt, K., … Bettler,
B. (2009). The GABA B1a isoform mediates heterosynaptic depression at hippocampal
mossy fiber synapses. Journal of Neuroscience. Society for Neuroscience.
https://doi.org/10.1523/JNEUROSCI.3697-08.2009
chicago: Guetg, Nicole, Riad Seddik, Réjan Vigot, Rostislav Tureček, Martin Gassmann,
Kaspar Vogt, Hans Bräuner Osborne, et al. “The GABA B1a Isoform Mediates Heterosynaptic
Depression at Hippocampal Mossy Fiber Synapses.” Journal of Neuroscience.
Society for Neuroscience, 2009. https://doi.org/10.1523/JNEUROSCI.3697-08.2009.
ieee: N. Guetg et al., “The GABA B1a isoform mediates heterosynaptic depression
at hippocampal mossy fiber synapses,” Journal of Neuroscience, vol. 29,
no. 5. Society for Neuroscience, pp. 1414–1423, 2009.
ista: Guetg N, Seddik R, Vigot R, Tureček R, Gassmann M, Vogt K, Bräuner Osborne
H, Shigemoto R, Kretz O, Frotscher M, Kulik Á, Bettler B. 2009. The GABA B1a isoform
mediates heterosynaptic depression at hippocampal mossy fiber synapses. Journal
of Neuroscience. 29(5), 1414–1423.
mla: Guetg, Nicole, et al. “The GABA B1a Isoform Mediates Heterosynaptic Depression
at Hippocampal Mossy Fiber Synapses.” Journal of Neuroscience, vol. 29,
no. 5, Society for Neuroscience, 2009, pp. 1414–23, doi:10.1523/JNEUROSCI.3697-08.2009.
short: N. Guetg, R. Seddik, R. Vigot, R. Tureček, M. Gassmann, K. Vogt, H. Bräuner
Osborne, R. Shigemoto, O. Kretz, M. Frotscher, Á. Kulik, B. Bettler, Journal of
Neuroscience 29 (2009) 1414–1423.
date_created: 2018-12-11T11:59:02Z
date_published: 2009-02-04T00:00:00Z
date_updated: 2021-01-12T06:59:01Z
day: '04'
doi: 10.1523/JNEUROSCI.3697-08.2009
extern: 1
intvolume: ' 29'
issue: '5'
month: '02'
page: 1414 - 1423
publication: Journal of Neuroscience
publication_status: published
publisher: Society for Neuroscience
publist_id: '4216'
quality_controlled: 0
status: public
title: The GABA B1a isoform mediates heterosynaptic depression at hippocampal mossy
fiber synapses
type: journal_article
volume: 29
year: '2009'
...
---
_id: '2682'
abstract:
- lang: eng
text: The living cell imaging using a two-photon microscope using gold nanoplates
and nanoparticle aggregates was demonstrated. The dimensions of the nanoplates
were determined through scanning electron microscopy (SEM) and atomic force microscopy.
The height of a 100 nm base-length nanotriangle was around 10 nm, while the height
of 300 nm base-length nanotriangle was around 12 nm. A spectrophotometer was also
used to determine the extinction spectra of gold nanoparticle colloids. Two-photon-induced
photoluminescence (TPIPL) under far-field excitation was tested for gold nanoplates
on a glass substrate using two-photon laser scanning microscopy (TPLSM). It was
observed that living-cell microscopic imaging can be carried out with TPIPL from
gold nanoplates and aggregated nanosphere. This method provided a platform for
developing tools for biological and biomedical studies.
author:
- first_name: Yuqiang
full_name: Jiang, Yuqiang
last_name: Jiang
- first_name: Noriko
full_name: Horimoto, Noriko N
last_name: Horimoto
- first_name: Kohei
full_name: Imura, Kohei
last_name: Imura
- first_name: Ko
full_name: Matsui, Ko
last_name: Matsui
- first_name: Ryuichi
full_name: Ryuichi Shigemoto
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
citation:
ama: Jiang Y, Horimoto N, Imura K, Matsui K, Shigemoto R. Bioimaging with two-photon-induced
luminescence from triangular nanoplates and nanoparticle aggregates of gold. Advanced
Materials. 2009;21(22):2309-2313. doi:10.1002/adma.200802312
apa: Jiang, Y., Horimoto, N., Imura, K., Matsui, K., & Shigemoto, R. (2009).
Bioimaging with two-photon-induced luminescence from triangular nanoplates and
nanoparticle aggregates of gold. Advanced Materials. Wiley-Blackwell. https://doi.org/10.1002/adma.200802312
chicago: Jiang, Yuqiang, Noriko Horimoto, Kohei Imura, Ko Matsui, and Ryuichi Shigemoto.
“Bioimaging with Two-Photon-Induced Luminescence from Triangular Nanoplates and
Nanoparticle Aggregates of Gold.” Advanced Materials. Wiley-Blackwell,
2009. https://doi.org/10.1002/adma.200802312.
ieee: Y. Jiang, N. Horimoto, K. Imura, K. Matsui, and R. Shigemoto, “Bioimaging
with two-photon-induced luminescence from triangular nanoplates and nanoparticle
aggregates of gold,” Advanced Materials, vol. 21, no. 22. Wiley-Blackwell,
pp. 2309–2313, 2009.
ista: Jiang Y, Horimoto N, Imura K, Matsui K, Shigemoto R. 2009. Bioimaging with
two-photon-induced luminescence from triangular nanoplates and nanoparticle aggregates
of gold. Advanced Materials. 21(22), 2309–2313.
mla: Jiang, Yuqiang, et al. “Bioimaging with Two-Photon-Induced Luminescence from
Triangular Nanoplates and Nanoparticle Aggregates of Gold.” Advanced Materials,
vol. 21, no. 22, Wiley-Blackwell, 2009, pp. 2309–13, doi:10.1002/adma.200802312.
short: Y. Jiang, N. Horimoto, K. Imura, K. Matsui, R. Shigemoto, Advanced Materials
21 (2009) 2309–2313.
date_created: 2018-12-11T11:59:02Z
date_published: 2009-06-12T00:00:00Z
date_updated: 2021-01-12T06:59:01Z
day: '12'
doi: 10.1002/adma.200802312
extern: 1
intvolume: ' 21'
issue: '22'
month: '06'
page: 2309 - 2313
publication: Advanced Materials
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4214'
quality_controlled: 0
status: public
title: Bioimaging with two-photon-induced luminescence from triangular nanoplates
and nanoparticle aggregates of gold
type: journal_article
volume: 21
year: '2009'
...
---
_id: '2683'
abstract:
- lang: eng
text: GABAb receptor (GABAbR)-mediated suppression of glutamate release is critical
for limiting glutamatergic transmission across the central nervous system (CNS).
Here we show that, upon tetanic stimulation of afferents to lateral amygdala,
presynaptic GABAbR-mediated inhibition only occurs in glutamatergic inputs to
principle neurons (PNs), not to interneurons (INs), despite the presence of GABAbR
in terminals to both types of neurons. The selectivity is caused by differential
local GABA accumulation; it requires GABA reuptake and parallels distinct spatial
distributions of presynaptic GABAbR in terminals to PNs and INs. Moreover, GABAbR-mediated
suppression of theta-burst-induced long-term potentiation (LTP) occurs only in
the inputs to PNs, not to INs. Thus, target-cell-specific control of glutamate
release by presynaptic GABAbR orchestrates the inhibitory dominance inside amygdala
and might contribute to prevention of nonadaptive defensive behaviors.
author:
- first_name: Bingxing
full_name: Pan, Bingxing
last_name: Pan
- first_name: Yu
full_name: Dong, Yu-Lin
last_name: Dong
- first_name: Wataru
full_name: Ito, Wataru
last_name: Ito
- first_name: Yuchio
full_name: Yanagawa, Yuchio
last_name: Yanagawa
- first_name: Ryuichi
full_name: Ryuichi Shigemoto
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Alexei
full_name: Morozov, Alexei A
last_name: Morozov
citation:
ama: Pan B, Dong Y, Ito W, Yanagawa Y, Shigemoto R, Morozov A. Selective gating
of glutamatergic inputs to excitatory neurons of amygdala by presynaptic GABAb
receptor. Neuron. 2009;61(6):917-929. doi:10.1016/j.neuron.2009.01.029
apa: Pan, B., Dong, Y., Ito, W., Yanagawa, Y., Shigemoto, R., & Morozov, A.
(2009). Selective gating of glutamatergic inputs to excitatory neurons of amygdala
by presynaptic GABAb receptor. Neuron. Elsevier. https://doi.org/10.1016/j.neuron.2009.01.029
chicago: Pan, Bingxing, Yu Dong, Wataru Ito, Yuchio Yanagawa, Ryuichi Shigemoto,
and Alexei Morozov. “Selective Gating of Glutamatergic Inputs to Excitatory Neurons
of Amygdala by Presynaptic GABAb Receptor.” Neuron. Elsevier, 2009. https://doi.org/10.1016/j.neuron.2009.01.029.
ieee: B. Pan, Y. Dong, W. Ito, Y. Yanagawa, R. Shigemoto, and A. Morozov, “Selective
gating of glutamatergic inputs to excitatory neurons of amygdala by presynaptic
GABAb receptor,” Neuron, vol. 61, no. 6. Elsevier, pp. 917–929, 2009.
ista: Pan B, Dong Y, Ito W, Yanagawa Y, Shigemoto R, Morozov A. 2009. Selective
gating of glutamatergic inputs to excitatory neurons of amygdala by presynaptic
GABAb receptor. Neuron. 61(6), 917–929.
mla: Pan, Bingxing, et al. “Selective Gating of Glutamatergic Inputs to Excitatory
Neurons of Amygdala by Presynaptic GABAb Receptor.” Neuron, vol. 61, no.
6, Elsevier, 2009, pp. 917–29, doi:10.1016/j.neuron.2009.01.029.
short: B. Pan, Y. Dong, W. Ito, Y. Yanagawa, R. Shigemoto, A. Morozov, Neuron 61
(2009) 917–929.
date_created: 2018-12-11T11:59:03Z
date_published: 2009-03-26T00:00:00Z
date_updated: 2021-01-12T06:59:02Z
day: '26'
doi: 10.1016/j.neuron.2009.01.029
extern: 1
intvolume: ' 61'
issue: '6'
month: '03'
page: 917 - 929
publication: Neuron
publication_status: published
publisher: Elsevier
publist_id: '4215'
quality_controlled: 0
status: public
title: Selective gating of glutamatergic inputs to excitatory neurons of amygdala
by presynaptic GABAb receptor
type: journal_article
volume: 61
year: '2009'
...
---
_id: '2684'
abstract:
- lang: eng
text: Calcium-activated potassium channels have been shown to be critically involved
in neuronal function, but an elucidation of their detailed roles awaits identification
of the microdomains where they are located. This study was undertaken to unravel
the precise subcellular distribution of the large-conductance calcium-activated
potassium channels (called BK, KCa1.1, or Slo1) in the somatodendritic compartment
of cerebellar Purkinje cells by means of postembedding immunogold cytochemistry
and SDS-digested freeze-fracture replica labeling (SDS-FRL). We found BK channels
to be unevenly distributed over the Purkinje cell plasma membrane. At distal dendritic
compartments, BK channels were scattered over the plasma membrane of dendritic
shafts and spines but absent from postsynaptic densities. At the soma and proximal
dendrites, BK channels formed two distinct pools. One pool was scattered over
the plasma membrane, whereas the other pool was clustered in plasma membrane domains
overlying subsurface cisterns. The labeling density ratio of clustered to scattered
channels was about 60:1, established in SDS-FRL. Subsurface cisterns, also called
hypolemmal cisterns, are subcompartments of the endoplasmic reticulum likely representing
calciosomes that unload and refill Ca2+ independently. Purkinje cell subsurface
cisterns are enriched in inositol 1,4,5-triphosphate receptors that mediate the
effects of several neurotransmitters, hormones, and growth factors by releasing
Ca2+ into the cytosol, generating local Ca2+ sparks. Such increases in cytosolic
[Ca2+] may be sufficient for BK channel activation. Clustered BK channels in the
plasma membrane may thus participate in building a functional unit (plasmerosome)
with the underlying calciosome that contributes significantly to local signaling
in Purkinje cells.
author:
- first_name: Walter
full_name: Walter Kaufmann
id: 3F99E422-F248-11E8-B48F-1D18A9856A87
last_name: Kaufmann
orcid: 0000-0001-9735-5315
- first_name: Francesco
full_name: Ferraguti, Francesco
last_name: Ferraguti
- first_name: Yugo
full_name: Fukazawa, Yugo
last_name: Fukazawa
- first_name: Yu
full_name: Kasugai, Yu
last_name: Kasugai
- first_name: Ryuichi
full_name: Ryuichi Shigemoto
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Petter
full_name: Laake, Petter
last_name: Laake
- first_name: Joseph
full_name: Sexton, Joseph A
last_name: Sexton
- first_name: Peter
full_name: Ruth, Peter
last_name: Ruth
- first_name: Georg
full_name: Wietzorrek, Georg
last_name: Wietzorrek
- first_name: Hans
full_name: Knaus, Hans G
last_name: Knaus
- first_name: Johan
full_name: Storm, Johan F
last_name: Storm
- first_name: Ole
full_name: Ottersen, Ole P
last_name: Ottersen
citation:
ama: Kaufmann W, Ferraguti F, Fukazawa Y, et al. Large-conductance calcium-activated
potassium channels in Purkinje cell plasma membranes are clustered at sites of
hypolemmal microdomains. Journal of Comparative Neurology. 2009;515(2):215-230.
doi:10.1002/cne.22066
apa: Kaufmann, W., Ferraguti, F., Fukazawa, Y., Kasugai, Y., Shigemoto, R., Laake,
P., … Ottersen, O. (2009). Large-conductance calcium-activated potassium channels
in Purkinje cell plasma membranes are clustered at sites of hypolemmal microdomains.
Journal of Comparative Neurology. Wiley-Blackwell. https://doi.org/10.1002/cne.22066
chicago: Kaufmann, Walter, Francesco Ferraguti, Yugo Fukazawa, Yu Kasugai, Ryuichi
Shigemoto, Petter Laake, Joseph Sexton, et al. “Large-Conductance Calcium-Activated
Potassium Channels in Purkinje Cell Plasma Membranes Are Clustered at Sites of
Hypolemmal Microdomains.” Journal of Comparative Neurology. Wiley-Blackwell,
2009. https://doi.org/10.1002/cne.22066.
ieee: W. Kaufmann et al., “Large-conductance calcium-activated potassium
channels in Purkinje cell plasma membranes are clustered at sites of hypolemmal
microdomains,” Journal of Comparative Neurology, vol. 515, no. 2. Wiley-Blackwell,
pp. 215–230, 2009.
ista: Kaufmann W, Ferraguti F, Fukazawa Y, Kasugai Y, Shigemoto R, Laake P, Sexton
J, Ruth P, Wietzorrek G, Knaus H, Storm J, Ottersen O. 2009. Large-conductance
calcium-activated potassium channels in Purkinje cell plasma membranes are clustered
at sites of hypolemmal microdomains. Journal of Comparative Neurology. 515(2),
215–230.
mla: Kaufmann, Walter, et al. “Large-Conductance Calcium-Activated Potassium Channels
in Purkinje Cell Plasma Membranes Are Clustered at Sites of Hypolemmal Microdomains.”
Journal of Comparative Neurology, vol. 515, no. 2, Wiley-Blackwell, 2009,
pp. 215–30, doi:10.1002/cne.22066.
short: W. Kaufmann, F. Ferraguti, Y. Fukazawa, Y. Kasugai, R. Shigemoto, P. Laake,
J. Sexton, P. Ruth, G. Wietzorrek, H. Knaus, J. Storm, O. Ottersen, Journal of
Comparative Neurology 515 (2009) 215–230.
date_created: 2018-12-11T11:59:03Z
date_published: 2009-07-10T00:00:00Z
date_updated: 2023-02-23T10:53:41Z
day: '10'
doi: 10.1002/cne.22066
extern: 1
intvolume: ' 515'
issue: '2'
month: '07'
page: 215 - 230
publication: Journal of Comparative Neurology
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4212'
quality_controlled: 0
status: public
title: Large-conductance calcium-activated potassium channels in Purkinje cell plasma
membranes are clustered at sites of hypolemmal microdomains
type: journal_article
volume: 515
year: '2009'
...
---
_id: '2685'
abstract:
- lang: eng
text: Conduction velocity (CV) of myelinated axons has been shown to be regulated
by oligodendrocytes even after myelination has been completed. However, how myelinating
oligodendrocytes regulate CV, and what the significance of this regulation is
for normal brain function remain unknown. To address these questions, we analyzed
a transgenic mouse line harboring extra copies of the myelin proteolipid protein
1 (plp1) gene (plp1tg/- mice) at 2 months of age. At this stage, the plp1tg/-
mice have an unaffected myelin structure with a normally appearing ion channel
distribution, but the CV in all axonal tracts tested in the CNS is greatly reduced.
We also found decreased axonal diameters and slightly abnormal paranodal structures,
both of which can be a cause for the reduced CV. Interestingly the plp1tg/- mice
showed altered anxiety-like behaviors, reduced prepulse inhibitions, spatial learning
deficits and working memory deficit, all of which are schizophrenia-related behaviors.
Our results implicate that abnormalities in the neuron-glia interactions at the
paranodal junctions can result in reduced CV in the CNS, which then induces behavioral
abnormalities related to schizophrenia.
author:
- first_name: Hisataka
full_name: Tanaka, Hisataka
last_name: Tanaka
- first_name: Jianmei
full_name: Ma, Jianmei
last_name: Ma
- first_name: Kenji
full_name: Tanaka, Kenji F
last_name: Tanaka
- first_name: Keizo
full_name: Takao, Keizo
last_name: Takao
- first_name: Munekazu
full_name: Komada, Munekazu
last_name: Komada
- first_name: Koichi
full_name: Tanda, Koichi
last_name: Tanda
- first_name: Ayaka
full_name: Suzuki, Ayaka
last_name: Suzuki
- first_name: Tomoko
full_name: Ishibashi, Tomoko
last_name: Ishibashi
- first_name: Hiroko
full_name: Baba, Hiroko
last_name: Baba
- first_name: Tadashi
full_name: Isa, Tadashi
last_name: Isa
- first_name: Ryuichi
full_name: Ryuichi Shigemoto
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Katsuhiko
full_name: Ono, Katsuhiko
last_name: Ono
- first_name: Tsuyoshi
full_name: Miyakawa, Tsuyoshi
last_name: Miyakawa
- first_name: Kazuhiro
full_name: Ikenaka, Kazuhiro
last_name: Ikenaka
citation:
ama: Tanaka H, Ma J, Tanaka K, et al. Mice with altered myelin proteolipid protein
gene expression display cognitive deficits accompanied by abnormal neuron-glia
interactions and decreased conduction velocities. Journal of Neuroscience.
2009;29(26):8363-8371. doi:10.1523/JNEUROSCI.3216-08.2009
apa: Tanaka, H., Ma, J., Tanaka, K., Takao, K., Komada, M., Tanda, K., … Ikenaka,
K. (2009). Mice with altered myelin proteolipid protein gene expression display
cognitive deficits accompanied by abnormal neuron-glia interactions and decreased
conduction velocities. Journal of Neuroscience. Society for Neuroscience.
https://doi.org/10.1523/JNEUROSCI.3216-08.2009
chicago: Tanaka, Hisataka, Jianmei Ma, Kenji Tanaka, Keizo Takao, Munekazu Komada,
Koichi Tanda, Ayaka Suzuki, et al. “Mice with Altered Myelin Proteolipid Protein
Gene Expression Display Cognitive Deficits Accompanied by Abnormal Neuron-Glia
Interactions and Decreased Conduction Velocities.” Journal of Neuroscience.
Society for Neuroscience, 2009. https://doi.org/10.1523/JNEUROSCI.3216-08.2009.
ieee: H. Tanaka et al., “Mice with altered myelin proteolipid protein gene
expression display cognitive deficits accompanied by abnormal neuron-glia interactions
and decreased conduction velocities,” Journal of Neuroscience, vol. 29,
no. 26. Society for Neuroscience, pp. 8363–8371, 2009.
ista: Tanaka H, Ma J, Tanaka K, Takao K, Komada M, Tanda K, Suzuki A, Ishibashi
T, Baba H, Isa T, Shigemoto R, Ono K, Miyakawa T, Ikenaka K. 2009. Mice with altered
myelin proteolipid protein gene expression display cognitive deficits accompanied
by abnormal neuron-glia interactions and decreased conduction velocities. Journal
of Neuroscience. 29(26), 8363–8371.
mla: Tanaka, Hisataka, et al. “Mice with Altered Myelin Proteolipid Protein Gene
Expression Display Cognitive Deficits Accompanied by Abnormal Neuron-Glia Interactions
and Decreased Conduction Velocities.” Journal of Neuroscience, vol. 29,
no. 26, Society for Neuroscience, 2009, pp. 8363–71, doi:10.1523/JNEUROSCI.3216-08.2009.
short: H. Tanaka, J. Ma, K. Tanaka, K. Takao, M. Komada, K. Tanda, A. Suzuki, T.
Ishibashi, H. Baba, T. Isa, R. Shigemoto, K. Ono, T. Miyakawa, K. Ikenaka, Journal
of Neuroscience 29 (2009) 8363–8371.
date_created: 2018-12-11T11:59:03Z
date_published: 2009-07-01T00:00:00Z
date_updated: 2021-01-12T06:59:02Z
day: '01'
doi: 10.1523/JNEUROSCI.3216-08.2009
extern: 1
intvolume: ' 29'
issue: '26'
month: '07'
page: 8363 - 8371
publication: Journal of Neuroscience
publication_status: published
publisher: Society for Neuroscience
publist_id: '4213'
quality_controlled: 0
status: public
title: Mice with altered myelin proteolipid protein gene expression display cognitive
deficits accompanied by abnormal neuron-glia interactions and decreased conduction
velocities
type: journal_article
volume: 29
year: '2009'
...