---
_id: '8477'
abstract:
- lang: eng
text: An optimized NMR experiment that combines the advantages of methyl-TROSY and
SOFAST-HMQC has been developed. It allows the recording of high quality methyl
1H−13C correlation spectra of protein assemblies of several hundreds of kDa in
a few seconds. The SOFAST-methyl-TROSY-based experiment offers completely new
opportunities for the study of structural and dynamic changes occurring in molecular
nanomachines while they perform their biological function in vitro.
article_processing_charge: No
article_type: original
author:
- first_name: Carlos
full_name: Amero, Carlos
last_name: Amero
- first_name: Paul
full_name: Schanda, Paul
id: 7B541462-FAF6-11E9-A490-E8DFE5697425
last_name: Schanda
orcid: 0000-0002-9350-7606
- first_name: M. Asunción
full_name: Durá, M. Asunción
last_name: Durá
- first_name: Isabel
full_name: Ayala, Isabel
last_name: Ayala
- first_name: Dominique
full_name: Marion, Dominique
last_name: Marion
- first_name: Bruno
full_name: Franzetti, Bruno
last_name: Franzetti
- first_name: Bernhard
full_name: Brutscher, Bernhard
last_name: Brutscher
- first_name: Jérôme
full_name: Boisbouvier, Jérôme
last_name: Boisbouvier
citation:
ama: Amero C, Schanda P, Durá MA, et al. Fast two-dimensional NMR spectroscopy
of high molecular weight protein assemblies. Journal of the American Chemical
Society. 2009;131(10):3448-3449. doi:10.1021/ja809880p
apa: Amero, C., Schanda, P., Durá, M. A., Ayala, I., Marion, D., Franzetti, B.,
… Boisbouvier, J. (2009). Fast two-dimensional NMR spectroscopy of high molecular
weight protein assemblies. Journal of the American Chemical Society. American
Chemical Society. https://doi.org/10.1021/ja809880p
chicago: Amero, Carlos, Paul Schanda, M. Asunción Durá, Isabel Ayala, Dominique
Marion, Bruno Franzetti, Bernhard Brutscher, and Jérôme Boisbouvier. “Fast Two-Dimensional
NMR Spectroscopy of High Molecular Weight Protein Assemblies.” Journal of the
American Chemical Society. American Chemical Society, 2009. https://doi.org/10.1021/ja809880p.
ieee: C. Amero et al., “Fast two-dimensional NMR spectroscopy of high molecular
weight protein assemblies,” Journal of the American Chemical Society, vol.
131, no. 10. American Chemical Society, pp. 3448–3449, 2009.
ista: Amero C, Schanda P, Durá MA, Ayala I, Marion D, Franzetti B, Brutscher B,
Boisbouvier J. 2009. Fast two-dimensional NMR spectroscopy of high molecular weight
protein assemblies. Journal of the American Chemical Society. 131(10), 3448–3449.
mla: Amero, Carlos, et al. “Fast Two-Dimensional NMR Spectroscopy of High Molecular
Weight Protein Assemblies.” Journal of the American Chemical Society, vol.
131, no. 10, American Chemical Society, 2009, pp. 3448–49, doi:10.1021/ja809880p.
short: C. Amero, P. Schanda, M.A. Durá, I. Ayala, D. Marion, B. Franzetti, B. Brutscher,
J. Boisbouvier, Journal of the American Chemical Society 131 (2009) 3448–3449.
date_created: 2020-09-18T10:12:01Z
date_published: 2009-02-25T00:00:00Z
date_updated: 2021-01-12T08:19:32Z
day: '25'
doi: 10.1021/ja809880p
extern: '1'
intvolume: ' 131'
issue: '10'
language:
- iso: eng
month: '02'
oa_version: None
page: 3448-3449
publication: Journal of the American Chemical Society
publication_identifier:
issn:
- 0002-7863
- 1520-5126
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
status: public
title: Fast two-dimensional NMR spectroscopy of high molecular weight protein assemblies
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 131
year: '2009'
...
---
_id: '8478'
abstract:
- lang: eng
text: Allosteric regulation is an effective mechanism of control in biological processes.
In allosteric proteins a signal originating at one site in the molecule is communicated
through the protein structure to trigger a specific response at a remote site.
Using NMR relaxation dispersion techniques we directly observe the dynamic process
through which the KIX domain of CREB binding protein communicates allosteric information
between binding sites. KIX mediates cooperativity between pairs of transcription
factors through binding to two distinct interaction surfaces in an allosteric
manner. We show that binding the activation domain of the mixed lineage leukemia
(MLL) transcription factor to KIX induces a redistribution of the relative populations
of KIX conformations toward a high-energy state in which the allosterically activated
second binding site is already preformed, consistent with the Monod−Wyman−Changeux
(WMC) model of allostery. The structural rearrangement process that links the
two conformers and by which allosteric information is communicated occurs with
a time constant of 3 ms at 27 °C. Our dynamic NMR data reveal that an evolutionarily
conserved network of hydrophobic amino acids constitutes the pathway through which
information is transmitted.
article_processing_charge: No
article_type: original
author:
- first_name: Sven
full_name: Brüschweiler, Sven
last_name: Brüschweiler
- first_name: Paul
full_name: Schanda, Paul
id: 7B541462-FAF6-11E9-A490-E8DFE5697425
last_name: Schanda
orcid: 0000-0002-9350-7606
- first_name: Karin
full_name: Kloiber, Karin
last_name: Kloiber
- first_name: Bernhard
full_name: Brutscher, Bernhard
last_name: Brutscher
- first_name: Georg
full_name: Kontaxis, Georg
last_name: Kontaxis
- first_name: Robert
full_name: Konrat, Robert
last_name: Konrat
- first_name: Martin
full_name: Tollinger, Martin
last_name: Tollinger
citation:
ama: Brüschweiler S, Schanda P, Kloiber K, et al. Direct observation of the dynamic
process underlying allosteric signal transmission. Journal of the American
Chemical Society. 2009;131(8):3063-3068. doi:10.1021/ja809947w
apa: Brüschweiler, S., Schanda, P., Kloiber, K., Brutscher, B., Kontaxis, G., Konrat,
R., & Tollinger, M. (2009). Direct observation of the dynamic process underlying
allosteric signal transmission. Journal of the American Chemical Society.
American Chemical Society. https://doi.org/10.1021/ja809947w
chicago: Brüschweiler, Sven, Paul Schanda, Karin Kloiber, Bernhard Brutscher, Georg
Kontaxis, Robert Konrat, and Martin Tollinger. “Direct Observation of the Dynamic
Process Underlying Allosteric Signal Transmission.” Journal of the American
Chemical Society. American Chemical Society, 2009. https://doi.org/10.1021/ja809947w.
ieee: S. Brüschweiler et al., “Direct observation of the dynamic process
underlying allosteric signal transmission,” Journal of the American Chemical
Society, vol. 131, no. 8. American Chemical Society, pp. 3063–3068, 2009.
ista: Brüschweiler S, Schanda P, Kloiber K, Brutscher B, Kontaxis G, Konrat R,
Tollinger M. 2009. Direct observation of the dynamic process underlying allosteric
signal transmission. Journal of the American Chemical Society. 131(8), 3063–3068.
mla: Brüschweiler, Sven, et al. “Direct Observation of the Dynamic Process Underlying
Allosteric Signal Transmission.” Journal of the American Chemical Society,
vol. 131, no. 8, American Chemical Society, 2009, pp. 3063–68, doi:10.1021/ja809947w.
short: S. Brüschweiler, P. Schanda, K. Kloiber, B. Brutscher, G. Kontaxis, R. Konrat,
M. Tollinger, Journal of the American Chemical Society 131 (2009) 3063–3068.
date_created: 2020-09-18T10:12:14Z
date_published: 2009-02-09T00:00:00Z
date_updated: 2021-01-12T08:19:33Z
day: '09'
doi: 10.1021/ja809947w
extern: '1'
intvolume: ' 131'
issue: '8'
language:
- iso: eng
month: '02'
oa_version: None
page: 3063-3068
publication: Journal of the American Chemical Society
publication_identifier:
issn:
- 0002-7863
- 1520-5126
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
status: public
title: Direct observation of the dynamic process underlying allosteric signal transmission
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 131
year: '2009'
...
---
_id: '8479'
abstract:
- lang: eng
text: Multidimensional NMR spectroscopy is a well-established technique for the
characterization of structure and fast-time-scale dynamics of highly populated
ground states of biological macromolecules. The investigation of short-lived excited
states that are important for molecular folding, misfolding and function, however,
remains a challenge for modern biomolecular NMR techniques. Off-equilibrium real-time
kinetic NMR methods allow direct observation of conformational or chemical changes
by following peak positions and intensities in a series of spectra recorded during
a kinetic event. Because standard multidimensional NMR methods required to yield
sufficient atom-resolution are intrinsically time-consuming, many interesting
phenomena are excluded from real-time NMR analysis. Recently, spatially encoded
ultrafast 2D NMR techniques have been proposed that allow one to acquire a 2D
NMR experiment within a single transient. In addition, when combined with the
SOFAST technique, such ultrafast experiments can be repeated at high rates. One
of the problems detected for such ultrafast protein NMR experiments is related
to the heteronuclear decoupling during detection with interferences between the
pulses and the oscillatory magnetic field gradients arising in this scheme. Here
we present a method for improved ultrafast data acquisition yielding higher signal
to noise and sharper lines in single-scan 2D NMR spectra. In combination with
a fast-mixing device, the recording of 1H–15N correlation spectra with repetition
rates of up to a few Hertz becomes feasible, enabling real-time studies of protein
kinetics occurring on time scales down to a few seconds.
article_processing_charge: No
article_type: original
author:
- first_name: Maayan
full_name: Gal, Maayan
last_name: Gal
- first_name: Thomas
full_name: Kern, Thomas
last_name: Kern
- first_name: Paul
full_name: Schanda, Paul
id: 7B541462-FAF6-11E9-A490-E8DFE5697425
last_name: Schanda
orcid: 0000-0002-9350-7606
- first_name: Lucio
full_name: Frydman, Lucio
last_name: Frydman
- first_name: Bernhard
full_name: Brutscher, Bernhard
last_name: Brutscher
citation:
ama: 'Gal M, Kern T, Schanda P, Frydman L, Brutscher B. An improved ultrafast 2D
NMR experiment: Towards atom-resolved real-time studies of protein kinetics at
multi-Hz rates. Journal of Biomolecular NMR. 2009;43:1-10. doi:10.1007/s10858-008-9284-9'
apa: 'Gal, M., Kern, T., Schanda, P., Frydman, L., & Brutscher, B. (2009). An
improved ultrafast 2D NMR experiment: Towards atom-resolved real-time studies
of protein kinetics at multi-Hz rates. Journal of Biomolecular NMR. Springer
Nature. https://doi.org/10.1007/s10858-008-9284-9'
chicago: 'Gal, Maayan, Thomas Kern, Paul Schanda, Lucio Frydman, and Bernhard Brutscher.
“An Improved Ultrafast 2D NMR Experiment: Towards Atom-Resolved Real-Time Studies
of Protein Kinetics at Multi-Hz Rates.” Journal of Biomolecular NMR. Springer
Nature, 2009. https://doi.org/10.1007/s10858-008-9284-9.'
ieee: 'M. Gal, T. Kern, P. Schanda, L. Frydman, and B. Brutscher, “An improved ultrafast
2D NMR experiment: Towards atom-resolved real-time studies of protein kinetics
at multi-Hz rates,” Journal of Biomolecular NMR, vol. 43. Springer Nature,
pp. 1–10, 2009.'
ista: 'Gal M, Kern T, Schanda P, Frydman L, Brutscher B. 2009. An improved ultrafast
2D NMR experiment: Towards atom-resolved real-time studies of protein kinetics
at multi-Hz rates. Journal of Biomolecular NMR. 43, 1–10.'
mla: 'Gal, Maayan, et al. “An Improved Ultrafast 2D NMR Experiment: Towards Atom-Resolved
Real-Time Studies of Protein Kinetics at Multi-Hz Rates.” Journal of Biomolecular
NMR, vol. 43, Springer Nature, 2009, pp. 1–10, doi:10.1007/s10858-008-9284-9.'
short: M. Gal, T. Kern, P. Schanda, L. Frydman, B. Brutscher, Journal of Biomolecular
NMR 43 (2009) 1–10.
date_created: 2020-09-18T10:12:20Z
date_published: 2009-01-01T00:00:00Z
date_updated: 2021-01-12T08:19:33Z
day: '01'
doi: 10.1007/s10858-008-9284-9
extern: '1'
intvolume: ' 43'
keyword:
- Spectroscopy
- Biochemistry
language:
- iso: eng
month: '01'
oa_version: None
page: 1-10
publication: Journal of Biomolecular NMR
publication_identifier:
issn:
- 0925-2738
- 1573-5001
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: 'An improved ultrafast 2D NMR experiment: Towards atom-resolved real-time studies
of protein kinetics at multi-Hz rates'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 43
year: '2009'
...
---
_id: '8508'
abstract:
- lang: eng
text: We study generic unfoldings of homoclinic tangencies of two-dimensional area-preserving
diffeomorphisms (conservative New house phenomena) and show that they give rise
to invariant hyperbolic sets of arbitrarily large Hausdorff dimension. As applications,
we discuss the size of the stochastic layer of a standard map and the Hausdorff
dimension of invariant hyperbolic sets for certain restricted three-body problems.
We avoid involved technical details and only concentrate on the ideas of the proof
of the presented results.
article_processing_charge: No
article_type: original
author:
- first_name: Anton
full_name: Gorodetski, Anton
last_name: Gorodetski
- first_name: Vadim
full_name: Kaloshin, Vadim
id: FE553552-CDE8-11E9-B324-C0EBE5697425
last_name: Kaloshin
orcid: 0000-0002-6051-2628
citation:
ama: Gorodetski A, Kaloshin V. Conservative homoclinic bifurcations and some applications.
Proceedings of the Steklov Institute of Mathematics. 2009;267(1):76-90.
doi:10.1134/s0081543809040063
apa: Gorodetski, A., & Kaloshin, V. (2009). Conservative homoclinic bifurcations
and some applications. Proceedings of the Steklov Institute of Mathematics.
Springer Nature. https://doi.org/10.1134/s0081543809040063
chicago: Gorodetski, Anton, and Vadim Kaloshin. “Conservative Homoclinic Bifurcations
and Some Applications.” Proceedings of the Steklov Institute of Mathematics.
Springer Nature, 2009. https://doi.org/10.1134/s0081543809040063.
ieee: A. Gorodetski and V. Kaloshin, “Conservative homoclinic bifurcations and some
applications,” Proceedings of the Steklov Institute of Mathematics, vol.
267, no. 1. Springer Nature, pp. 76–90, 2009.
ista: Gorodetski A, Kaloshin V. 2009. Conservative homoclinic bifurcations and some
applications. Proceedings of the Steklov Institute of Mathematics. 267(1), 76–90.
mla: Gorodetski, Anton, and Vadim Kaloshin. “Conservative Homoclinic Bifurcations
and Some Applications.” Proceedings of the Steklov Institute of Mathematics,
vol. 267, no. 1, Springer Nature, 2009, pp. 76–90, doi:10.1134/s0081543809040063.
short: A. Gorodetski, V. Kaloshin, Proceedings of the Steklov Institute of Mathematics
267 (2009) 76–90.
date_created: 2020-09-18T10:48:03Z
date_published: 2009-12-01T00:00:00Z
date_updated: 2021-01-12T08:19:46Z
day: '01'
doi: 10.1134/s0081543809040063
extern: '1'
intvolume: ' 267'
issue: '1'
keyword:
- Mathematics (miscellaneous)
language:
- iso: eng
month: '12'
oa_version: None
page: 76-90
publication: Proceedings of the Steklov Institute of Mathematics
publication_identifier:
issn:
- 0081-5438
- 1531-8605
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Conservative homoclinic bifurcations and some applications
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 267
year: '2009'
...
---
_id: '88'
abstract:
- lang: eng
text: 'We have developed a tunable source of Mie scale microdroplet aerosols that
can be used for the generation of energetic ions. To demonstrate this potential,
a terawatt Ti: Al2 O3 laser focused to 2×10 19 W/cm2 was used to irradiate heavy
water (D2 O) aerosols composed of micron-scale droplets. Energetic deuterium ions,
which were generated in the laser-droplet interaction, produced deuterium-deuterium
fusion with approximately 2×10^3 fusion neutrons measured per joule of incident
laser energy. '
acknowledgement: This work was supported by the National Science Foundation under
Grant Nos. PHY-0456898, PHY-0757989, and PHY-0456870 and the National Nuclear Security
Administration under Cooperative Agreement No. DE-FC52-03NA00156. Acknowledgment
is made to the Donors of the Petroleum Research Fund administered by the American
Chemical Society for partial support of this research.
article_number: '063503'
author:
- first_name: Andrew P
full_name: Higginbotham, Andrew P
id: 4AD6785A-F248-11E8-B48F-1D18A9856A87
last_name: Higginbotham
orcid: 0000-0003-2607-2363
- first_name: Octavi
full_name: Semonin, Octavi
last_name: Semonin
- first_name: S
full_name: Bruce, S
last_name: Bruce
- first_name: C
full_name: Chan, C
last_name: Chan
- first_name: M
full_name: Maindi, M
last_name: Maindi
- first_name: Tom
full_name: Donnelly, Tom
last_name: Donnelly
- first_name: M
full_name: Maurer, M
last_name: Maurer
- first_name: Woosuk
full_name: Bang, Woosuk
last_name: Bang
- first_name: I.V
full_name: Churina, I.V
last_name: Churina
- first_name: Jens
full_name: Osterholz, Jens
last_name: Osterholz
- first_name: I
full_name: Kim, I
last_name: Kim
- first_name: Aaron
full_name: Bernstein, Aaron
last_name: Bernstein
- first_name: Todd
full_name: Ditmire, Todd
last_name: Ditmire
citation:
ama: Higginbotham AP, Semonin O, Bruce S, et al. Generation of Mie size microdroplet
aerosols with applications in laser-driven fusion experiments. Review of Scientific
Instruments. 2009;80(6). doi:10.1063/1.3155302
apa: Higginbotham, A. P., Semonin, O., Bruce, S., Chan, C., Maindi, M., Donnelly,
T., … Ditmire, T. (2009). Generation of Mie size microdroplet aerosols with applications
in laser-driven fusion experiments. Review of Scientific Instruments. American
Institute of Physics. https://doi.org/10.1063/1.3155302
chicago: Higginbotham, Andrew P, Octavi Semonin, S Bruce, C Chan, M Maindi, Tom
Donnelly, M Maurer, et al. “Generation of Mie Size Microdroplet Aerosols with
Applications in Laser-Driven Fusion Experiments.” Review of Scientific Instruments.
American Institute of Physics, 2009. https://doi.org/10.1063/1.3155302.
ieee: A. P. Higginbotham et al., “Generation of Mie size microdroplet aerosols
with applications in laser-driven fusion experiments,” Review of Scientific
Instruments, vol. 80, no. 6. American Institute of Physics, 2009.
ista: Higginbotham AP, Semonin O, Bruce S, Chan C, Maindi M, Donnelly T, Maurer
M, Bang W, Churina I., Osterholz J, Kim I, Bernstein A, Ditmire T. 2009. Generation
of Mie size microdroplet aerosols with applications in laser-driven fusion experiments.
Review of Scientific Instruments. 80(6), 063503.
mla: Higginbotham, Andrew P., et al. “Generation of Mie Size Microdroplet Aerosols
with Applications in Laser-Driven Fusion Experiments.” Review of Scientific
Instruments, vol. 80, no. 6, 063503, American Institute of Physics, 2009,
doi:10.1063/1.3155302.
short: A.P. Higginbotham, O. Semonin, S. Bruce, C. Chan, M. Maindi, T. Donnelly,
M. Maurer, W. Bang, I.. Churina, J. Osterholz, I. Kim, A. Bernstein, T. Ditmire,
Review of Scientific Instruments 80 (2009).
date_created: 2018-12-11T11:44:34Z
date_published: 2009-06-25T00:00:00Z
date_updated: 2021-01-12T08:21:06Z
day: '25'
doi: 10.1063/1.3155302
extern: '1'
external_id:
pmid:
- ' 19566203'
intvolume: ' 80'
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.osti.gov/biblio/22053583
month: '06'
oa: 1
oa_version: Submitted Version
pmid: 1
publication: Review of Scientific Instruments
publication_status: published
publisher: American Institute of Physics
publist_id: '7966'
quality_controlled: '1'
status: public
title: Generation of Mie size microdroplet aerosols with applications in laser-driven
fusion experiments
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 80
year: '2009'
...
---
_id: '164'
abstract:
- lang: eng
text: Let g be a cubic polynomial with integer coefficients and n>9 variables,
and assume that the congruence g=0 modulo p^k is soluble for all prime powers
p^k. We show that the equation g=0 has infinitely many integer solutions when
the cubic part of g defines a projective hypersurface with singular locus of dimension
<n-10. The proof is based on the Hardy-Littlewood circle method.
article_processing_charge: No
arxiv: 1
author:
- first_name: Timothy D
full_name: Browning, Timothy D
id: 35827D50-F248-11E8-B48F-1D18A9856A87
last_name: Browning
orcid: 0000-0002-8314-0177
- first_name: Roger
full_name: Heath Brown, Roger
last_name: Heath Brown
citation:
ama: 'Browning TD, Heath Brown R. Integral points on cubic hypersurfaces. In: Analytic
Number Theory: Essays in Honour of Klaus Roth. Cambridge University Press;
2009:75-90.'
apa: 'Browning, T. D., & Heath Brown, R. (2009). Integral points on cubic hypersurfaces.
In Analytic Number Theory: Essays in honour of Klaus Roth (pp. 75–90).
Cambridge University Press.'
chicago: 'Browning, Timothy D, and Roger Heath Brown. “Integral Points on Cubic
Hypersurfaces.” In Analytic Number Theory: Essays in Honour of Klaus Roth,
75–90. Cambridge University Press, 2009.'
ieee: 'T. D. Browning and R. Heath Brown, “Integral points on cubic hypersurfaces,”
in Analytic Number Theory: Essays in honour of Klaus Roth, Cambridge University
Press, 2009, pp. 75–90.'
ista: 'Browning TD, Heath Brown R. 2009.Integral points on cubic hypersurfaces.
In: Analytic Number Theory: Essays in honour of Klaus Roth. , 75–90.'
mla: 'Browning, Timothy D., and Roger Heath Brown. “Integral Points on Cubic Hypersurfaces.”
Analytic Number Theory: Essays in Honour of Klaus Roth, Cambridge University
Press, 2009, pp. 75–90.'
short: 'T.D. Browning, R. Heath Brown, in:, Analytic Number Theory: Essays in Honour
of Klaus Roth, Cambridge University Press, 2009, pp. 75–90.'
date_created: 2018-12-11T11:44:58Z
date_published: 2009-01-31T00:00:00Z
date_updated: 2021-01-12T06:52:11Z
day: '31'
extern: '1'
external_id:
arxiv:
- '0611086'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/math/0611086
month: '01'
oa: 1
oa_version: Preprint
page: 75 - 90
publication: 'Analytic Number Theory: Essays in honour of Klaus Roth'
publication_status: published
publisher: Cambridge University Press
publist_id: '7757'
quality_controlled: '1'
status: public
title: Integral points on cubic hypersurfaces
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2009'
...
---
_id: '165'
abstract:
- lang: eng
text: We survey the state of affairs for the distribution of ℚ-rational points on
non-singular del Pezzo surfaces of low degree, highlighting the recent resolution
of Manin's conjecture for a non-singular del Pezzo surface of degree 4 by la Bretèche
and Browning.
acknowledgement: Proceedings of the 5th China-Japan Seminar
alternative_title:
- Series on number theory and its application
author:
- first_name: Timothy D
full_name: Timothy Browning
id: 35827D50-F248-11E8-B48F-1D18A9856A87
last_name: Browning
orcid: 0000-0002-8314-0177
citation:
ama: 'Browning TD. Resent progress on the quantitative arithmetic of del Pezzo surfaces.
In: Aoki T, Kanemitsu S, Liu J, eds. Vol 6. World Scientific Publishing; 2009:1-18.
doi:https://doi.org/10.1142/9789814289924_0001'
apa: 'Browning, T. D. (2009). Resent progress on the quantitative arithmetic of
del Pezzo surfaces. In T. Aoki, S. Kanemitsu, & J. Liu (Eds.) (Vol. 6, pp.
1–18). Presented at the Number Theory: Dreaming in dreams, World Scientific Publishing.
https://doi.org/10.1142/9789814289924_0001'
chicago: Browning, Timothy D. “Resent Progress on the Quantitative Arithmetic of
Del Pezzo Surfaces.” edited by Takashi Aoki, Shigeru Kanemitsu, and Jianya Liu,
6:1–18. World Scientific Publishing, 2009. https://doi.org/10.1142/9789814289924_0001.
ieee: 'T. D. Browning, “Resent progress on the quantitative arithmetic of del Pezzo
surfaces,” presented at the Number Theory: Dreaming in dreams, 2009, vol. 6, pp.
1–18.'
ista: 'Browning TD. 2009. Resent progress on the quantitative arithmetic of del
Pezzo surfaces. Number Theory: Dreaming in dreams, Series on number theory and
its application, vol. 6, 1–18.'
mla: Browning, Timothy D. Resent Progress on the Quantitative Arithmetic of Del
Pezzo Surfaces. Edited by Takashi Aoki et al., vol. 6, World Scientific Publishing,
2009, pp. 1–18, doi:https://doi.org/10.1142/9789814289924_0001.
short: T.D. Browning, in:, T. Aoki, S. Kanemitsu, J. Liu (Eds.), World Scientific
Publishing, 2009, pp. 1–18.
conference:
name: 'Number Theory: Dreaming in dreams'
date_created: 2018-12-11T11:44:58Z
date_published: 2009-08-24T00:00:00Z
date_updated: 2021-01-12T06:52:15Z
day: '24'
doi: https://doi.org/10.1142/9789814289924_0001
editor:
- first_name: Takashi
full_name: Aoki, Takashi
last_name: Aoki
- first_name: Shigeru
full_name: Kanemitsu, Shigeru
last_name: Kanemitsu
- first_name: Jianya
full_name: Liu, Jianya
last_name: Liu
extern: 1
intvolume: ' 6'
month: '08'
page: 1 - 18
publication_status: published
publisher: World Scientific Publishing
publist_id: '7756'
quality_controlled: 0
status: public
title: Resent progress on the quantitative arithmetic of del Pezzo surfaces
type: conference
volume: 6
year: '2009'
...
---
_id: '168'
abstract:
- lang: eng
text: The arithmetic of ternary diagonal equation is considered for degree d >1,
with the outcome that the set of coefficients for which the equation admits a
non-zero integer solution is shown to have density zero.
alternative_title:
- Contemporary Mathematics
author:
- first_name: Timothy D
full_name: Timothy Browning
id: 35827D50-F248-11E8-B48F-1D18A9856A87
last_name: Browning
orcid: 0000-0002-8314-0177
- first_name: Rainer
full_name: Dietmann, Rainer
last_name: Dietmann
citation:
ama: 'Browning TD, Dietmann R. Solubility of Fermat equations. In: Quadratic
Forms - Algebra, Arithmetic and Geometry. Vol 493. American Mathematical Society;
2009:99-106. doi:http://dx.doi.org/10.1090/conm/493'
apa: Browning, T. D., & Dietmann, R. (2009). Solubility of Fermat equations.
In Quadratic Forms - algebra, arithmetic and geometry (Vol. 493, pp. 99–106).
American Mathematical Society. http://dx.doi.org/10.1090/conm/493
chicago: Browning, Timothy D, and Rainer Dietmann. “Solubility of Fermat Equations.”
In Quadratic Forms - Algebra, Arithmetic and Geometry, 493:99–106. American
Mathematical Society, 2009. http://dx.doi.org/10.1090/conm/493.
ieee: T. D. Browning and R. Dietmann, “Solubility of Fermat equations,” in Quadratic
Forms - algebra, arithmetic and geometry, vol. 493, American Mathematical
Society, 2009, pp. 99–106.
ista: 'Browning TD, Dietmann R. 2009.Solubility of Fermat equations. In: Quadratic
Forms - algebra, arithmetic and geometry. Contemporary Mathematics, vol. 493,
99–106.'
mla: Browning, Timothy D., and Rainer Dietmann. “Solubility of Fermat Equations.”
Quadratic Forms - Algebra, Arithmetic and Geometry, vol. 493, American
Mathematical Society, 2009, pp. 99–106, doi:http://dx.doi.org/10.1090/conm/493.
short: T.D. Browning, R. Dietmann, in:, Quadratic Forms - Algebra, Arithmetic and
Geometry, American Mathematical Society, 2009, pp. 99–106.
date_created: 2018-12-11T11:44:59Z
date_published: 2009-01-01T00:00:00Z
date_updated: 2021-01-12T06:52:29Z
day: '01'
doi: http://dx.doi.org/10.1090/conm/493
extern: 1
intvolume: ' 493'
main_file_link:
- open_access: '0'
url: https://arxiv.org/abs/0805.3354
month: '01'
page: 99 - 106
publication: Quadratic Forms - algebra, arithmetic and geometry
publication_status: published
publisher: American Mathematical Society
publist_id: '7753'
quality_controlled: 0
status: public
title: Solubility of Fermat equations
type: book_chapter
volume: 493
year: '2009'
...
---
_id: '1718'
abstract:
- lang: eng
text: Morphogens act as graded positional cues to control cell fate specification
in many developing tissues. This concept, in which a signaling gradient regulates
differential gene expression in a concentration-dependent manner, has received
considerable experimental support. Nevertheless, several recent studies have challenged
the straightforward model of morphogen activity. In particular, the observation
that pattern formation is a dynamic process has raised questions about the influence
of time on morphogen activity. Here we propose that the spatiotemporal dynamics
of the cellular response to a morphogen gradient depend on a combination of temporal
alterations to the morphogen gradient itself, the dynamics of its signal transduction
and downstream interactions between target genes.
acknowledgement: EK is supported by an EMBO LTF, AK by a FEBS fellowship, and JB by
MRC (UK) and the Wellcome Trust
author:
- first_name: Eva
full_name: Kutějová, Eva
last_name: Kutějová
- first_name: James
full_name: Briscoe, James
last_name: Briscoe
- first_name: Anna
full_name: Anna Kicheva
id: 3959A2A0-F248-11E8-B48F-1D18A9856A87
last_name: Kicheva
orcid: 0000-0003-4509-4998
citation:
ama: Kutějová E, Briscoe J, Kicheva A. Temporal dynamics of patterning by morphogen
gradients. Current Opinion in Genetics & Development. 2009;19(4):315-322.
doi:10.1016/j.gde.2009.05.004
apa: Kutějová, E., Briscoe, J., & Kicheva, A. (2009). Temporal dynamics of patterning
by morphogen gradients. Current Opinion in Genetics & Development.
Elsevier. https://doi.org/10.1016/j.gde.2009.05.004
chicago: Kutějová, Eva, James Briscoe, and Anna Kicheva. “Temporal Dynamics of Patterning
by Morphogen Gradients.” Current Opinion in Genetics & Development.
Elsevier, 2009. https://doi.org/10.1016/j.gde.2009.05.004.
ieee: E. Kutějová, J. Briscoe, and A. Kicheva, “Temporal dynamics of patterning
by morphogen gradients,” Current Opinion in Genetics & Development,
vol. 19, no. 4. Elsevier, pp. 315–322, 2009.
ista: Kutějová E, Briscoe J, Kicheva A. 2009. Temporal dynamics of patterning by
morphogen gradients. Current Opinion in Genetics & Development. 19(4), 315–322.
mla: Kutějová, Eva, et al. “Temporal Dynamics of Patterning by Morphogen Gradients.”
Current Opinion in Genetics & Development, vol. 19, no. 4, Elsevier,
2009, pp. 315–22, doi:10.1016/j.gde.2009.05.004.
short: E. Kutějová, J. Briscoe, A. Kicheva, Current Opinion in Genetics & Development
19 (2009) 315–322.
date_created: 2018-12-11T11:53:38Z
date_published: 2009-08-01T00:00:00Z
date_updated: 2021-01-12T06:52:44Z
day: '01'
doi: 10.1016/j.gde.2009.05.004
extern: 1
intvolume: ' 19'
issue: '4'
month: '08'
page: 315 - 322
publication: Current Opinion in Genetics & Development
publication_status: published
publisher: Elsevier
publist_id: '5410'
quality_controlled: 0
status: public
title: Temporal dynamics of patterning by morphogen gradients
type: journal_article
volume: 19
year: '2009'
...
---
_id: '1720'
abstract:
- lang: eng
text: How morphogen gradients are formed in target tissues is a key question for
understanding the mechanisms of morphological patterning. Here, we review different
mechanisms of morphogen gradient formation from theoretical and experimental points
of view. First, a simple, comprehensive overview of the underlying biophysical
principles of several mechanisms of gradient formation is provided. We then discuss
the advantages and limitations of different experimental approaches to gradient
formation analysis.
author:
- first_name: Ortrud
full_name: Wartlick, Ortrud
last_name: Wartlick
- first_name: Anna
full_name: Anna Kicheva
id: 3959A2A0-F248-11E8-B48F-1D18A9856A87
last_name: Kicheva
orcid: 0000-0003-4509-4998
- first_name: Marcos
full_name: González-Gaitán, Marcos A
last_name: González Gaitán
citation:
ama: Wartlick O, Kicheva A, González Gaitán M. Morphogen gradient formation . Cold
Spring Harbor perspectives in biology. 2009;1(3). doi:10.1101/cshperspect.a001255
apa: Wartlick, O., Kicheva, A., & González Gaitán, M. (2009). Morphogen gradient
formation . Cold Spring Harbor Perspectives in Biology. Cold Spring Harbor
Laboratory Press. https://doi.org/10.1101/cshperspect.a001255
chicago: Wartlick, Ortrud, Anna Kicheva, and Marcos González Gaitán. “Morphogen
Gradient Formation .” Cold Spring Harbor Perspectives in Biology. Cold
Spring Harbor Laboratory Press, 2009. https://doi.org/10.1101/cshperspect.a001255.
ieee: O. Wartlick, A. Kicheva, and M. González Gaitán, “Morphogen gradient formation
,” Cold Spring Harbor perspectives in biology, vol. 1, no. 3. Cold Spring
Harbor Laboratory Press, 2009.
ista: Wartlick O, Kicheva A, González Gaitán M. 2009. Morphogen gradient formation
. Cold Spring Harbor perspectives in biology. 1(3).
mla: Wartlick, Ortrud, et al. “Morphogen Gradient Formation .” Cold Spring Harbor
Perspectives in Biology, vol. 1, no. 3, Cold Spring Harbor Laboratory Press,
2009, doi:10.1101/cshperspect.a001255.
short: O. Wartlick, A. Kicheva, M. González Gaitán, Cold Spring Harbor Perspectives
in Biology 1 (2009).
date_created: 2018-12-11T11:53:39Z
date_published: 2009-09-01T00:00:00Z
date_updated: 2021-01-12T06:52:45Z
day: '01'
doi: 10.1101/cshperspect.a001255
extern: 1
intvolume: ' 1'
issue: '3'
month: '09'
publication: Cold Spring Harbor perspectives in biology
publication_status: published
publisher: Cold Spring Harbor Laboratory Press
publist_id: '5409'
quality_controlled: 0
status: public
title: 'Morphogen gradient formation '
type: journal_article
volume: 1
year: '2009'
...
---
_id: '1766'
abstract:
- lang: eng
text: We demonstrate the time-resolved driving of two-photon blue sideband transitions
between superconducting qubits and a transmission line resonator. As an example
of using these sideband transitions for a two-qubit operation, we implement a
pulse sequence that first entangles one qubit with the resonator and subsequently
distributes the entanglement between two qubits. We show the generation of 75%
fidelity Bell states by this method. The full density matrix of the two-qubit
system is extracted using joint measurement and quantum state tomography and shows
close agreement with numerical simulation.
acknowledgement: This work was supported by ETH Zurich, the Swiss National Science
Foundation, and by the EC via the EuroSQIP project and the Marie-Curie program (P.
J. L.)
author:
- first_name: Peter
full_name: Leek, Peter J
last_name: Leek
- first_name: Stefan
full_name: Filipp, Stefan
last_name: Filipp
- first_name: Patrick
full_name: Maurer, Patrick
last_name: Maurer
- first_name: Matthias
full_name: Baur, Matthias P
last_name: Baur
- first_name: R
full_name: Bianchetti, R
last_name: Bianchetti
- first_name: Johannes M
full_name: Johannes Fink
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
- first_name: M
full_name: Göppl, M
last_name: Göppl
- first_name: L.
full_name: Steffen, L. Kraig
last_name: Steffen
- first_name: Andreas
full_name: Wallraff, Andreas
last_name: Wallraff
citation:
ama: Leek P, Filipp S, Maurer P, et al. Using sideband transitions for two-qubit
operations in superconducting circuits. Physical Review B - Condensed Matter
and Materials Physics. 2009;79(18). doi:10.1103/PhysRevB.79.180511
apa: Leek, P., Filipp, S., Maurer, P., Baur, M., Bianchetti, R., Fink, J. M., …
Wallraff, A. (2009). Using sideband transitions for two-qubit operations in superconducting
circuits. Physical Review B - Condensed Matter and Materials Physics. American
Physical Society. https://doi.org/10.1103/PhysRevB.79.180511
chicago: Leek, Peter, Stefan Filipp, Patrick Maurer, Matthias Baur, R Bianchetti,
Johannes M Fink, M Göppl, L. Steffen, and Andreas Wallraff. “Using Sideband Transitions
for Two-Qubit Operations in Superconducting Circuits.” Physical Review B -
Condensed Matter and Materials Physics. American Physical Society, 2009. https://doi.org/10.1103/PhysRevB.79.180511.
ieee: P. Leek et al., “Using sideband transitions for two-qubit operations
in superconducting circuits,” Physical Review B - Condensed Matter and Materials
Physics, vol. 79, no. 18. American Physical Society, 2009.
ista: Leek P, Filipp S, Maurer P, Baur M, Bianchetti R, Fink JM, Göppl M, Steffen
L, Wallraff A. 2009. Using sideband transitions for two-qubit operations in superconducting
circuits. Physical Review B - Condensed Matter and Materials Physics. 79(18).
mla: Leek, Peter, et al. “Using Sideband Transitions for Two-Qubit Operations in
Superconducting Circuits.” Physical Review B - Condensed Matter and Materials
Physics, vol. 79, no. 18, American Physical Society, 2009, doi:10.1103/PhysRevB.79.180511.
short: P. Leek, S. Filipp, P. Maurer, M. Baur, R. Bianchetti, J.M. Fink, M. Göppl,
L. Steffen, A. Wallraff, Physical Review B - Condensed Matter and Materials Physics
79 (2009).
date_created: 2018-12-11T11:53:54Z
date_published: 2009-05-01T00:00:00Z
date_updated: 2021-01-12T06:53:04Z
day: '01'
doi: 10.1103/PhysRevB.79.180511
extern: 1
intvolume: ' 79'
issue: '18'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/0812.2678
month: '05'
oa: 1
publication: Physical Review B - Condensed Matter and Materials Physics
publication_status: published
publisher: American Physical Society
publist_id: '5354'
quality_controlled: 0
status: public
title: Using sideband transitions for two-qubit operations in superconducting circuits
type: journal_article
volume: 79
year: '2009'
...
---
_id: '1767'
abstract:
- lang: eng
text: We present spectroscopic measurements of the Autler-Townes doublet and the
sidebands of the Mollow triplet in a driven superconducting qubit. The ground
to first excited state transition of the qubit is strongly pumped while the resulting
dressed qubit spectrum is probed with a weak tone. The corresponding transitions
are detected using dispersive readout of the qubit coupled off resonantly to a
microwave transmission line resonator. The observed frequencies of the Autler-Townes
and Mollow spectral lines are in good agreement with a dispersive Jaynes-Cummings
model taking into account higher excited qubit states and dispersive level shifts
due to off-resonant drives.
acknowledgement: This work was supported by the Swiss National Science Foundation
and by ETH Zürich. P. J. L. acknowledges support from the EC via an Intra-European
Marie-Curie Fellowship. A. B. was supported by NSERC, CIFAR, FQRNT, and Alfred P.
Sloan Foundation
author:
- first_name: Matthias
full_name: Baur, Matthias P
last_name: Baur
- first_name: Stefan
full_name: Filipp, Stefan
last_name: Filipp
- first_name: R
full_name: Bianchetti, R
last_name: Bianchetti
- first_name: Johannes M
full_name: Johannes Fink
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
- first_name: M
full_name: Göppl, M
last_name: Göppl
- first_name: L.
full_name: Steffen, L. Kraig
last_name: Steffen
- first_name: Peter
full_name: Leek, Peter J
last_name: Leek
- first_name: Alexandre
full_name: Blais, Alexandre
last_name: Blais
- first_name: Andreas
full_name: Wallraff, Andreas
last_name: Wallraff
citation:
ama: Baur M, Filipp S, Bianchetti R, et al. Measurement of autler-townes and mollow
transitions in a strongly driven superconducting qubit. Physical Review Letters.
2009;102(24). doi:10.1103/PhysRevLett.102.243602
apa: Baur, M., Filipp, S., Bianchetti, R., Fink, J. M., Göppl, M., Steffen, L.,
… Wallraff, A. (2009). Measurement of autler-townes and mollow transitions in
a strongly driven superconducting qubit. Physical Review Letters. American
Physical Society. https://doi.org/10.1103/PhysRevLett.102.243602
chicago: Baur, Matthias, Stefan Filipp, R Bianchetti, Johannes M Fink, M Göppl,
L. Steffen, Peter Leek, Alexandre Blais, and Andreas Wallraff. “Measurement of
Autler-Townes and Mollow Transitions in a Strongly Driven Superconducting Qubit.”
Physical Review Letters. American Physical Society, 2009. https://doi.org/10.1103/PhysRevLett.102.243602.
ieee: M. Baur et al., “Measurement of autler-townes and mollow transitions
in a strongly driven superconducting qubit,” Physical Review Letters, vol.
102, no. 24. American Physical Society, 2009.
ista: Baur M, Filipp S, Bianchetti R, Fink JM, Göppl M, Steffen L, Leek P, Blais
A, Wallraff A. 2009. Measurement of autler-townes and mollow transitions in a
strongly driven superconducting qubit. Physical Review Letters. 102(24).
mla: Baur, Matthias, et al. “Measurement of Autler-Townes and Mollow Transitions
in a Strongly Driven Superconducting Qubit.” Physical Review Letters, vol.
102, no. 24, American Physical Society, 2009, doi:10.1103/PhysRevLett.102.243602.
short: M. Baur, S. Filipp, R. Bianchetti, J.M. Fink, M. Göppl, L. Steffen, P. Leek,
A. Blais, A. Wallraff, Physical Review Letters 102 (2009).
date_created: 2018-12-11T11:53:54Z
date_published: 2009-06-19T00:00:00Z
date_updated: 2021-01-12T06:53:04Z
day: '19'
doi: 10.1103/PhysRevLett.102.243602
extern: 1
intvolume: ' 102'
issue: '24'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/0812.4384
month: '06'
oa: 1
publication: Physical Review Letters
publication_status: published
publisher: American Physical Society
publist_id: '5352'
quality_controlled: 0
status: public
title: Measurement of autler-townes and mollow transitions in a strongly driven superconducting
qubit
type: journal_article
volume: 102
year: '2009'
...
---
_id: '1768'
abstract:
- lang: eng
text: Quantum state tomography is an important tool in quantum information science
for complete characterization of multiqubit states and their correlations. Here
we report a method to perform a joint simultaneous readout of two superconducting
qubits dispersively coupled to the same mode of a microwave transmission line
resonator. The nonlinear dependence of the resonator transmission on the qubit
state dependent cavity frequency allows us to extract the full two-qubit correlations
without the need for single-shot readout of individual qubits. We employ standard
tomographic techniques to reconstruct the density matrix of two-qubit quantum
states.
acknowledgement: This work was supported by Swiss National Science Foundation (SNF)
and ETH Zurich. P. J. L. was supported by the EC with a MC-EIF, J. M. G. by CIFAR,
MRI, MITACS, and NSERC, and A. B. by NSERC and CIFAR
author:
- first_name: Stefan
full_name: Filipp, Stefan
last_name: Filipp
- first_name: Patrick
full_name: Maurer, Patrick
last_name: Maurer
- first_name: Peter
full_name: Leek, Peter J
last_name: Leek
- first_name: Matthias
full_name: Baur, Matthias P
last_name: Baur
- first_name: R
full_name: Bianchetti, R
last_name: Bianchetti
- first_name: Johannes M
full_name: Johannes Fink
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
- first_name: M
full_name: Göppl, M
last_name: Göppl
- first_name: L.
full_name: Steffen, L. Kraig
last_name: Steffen
- first_name: Jay
full_name: Gambetta, Jay M
last_name: Gambetta
- first_name: Alexandre
full_name: Blais, Alexandre
last_name: Blais
- first_name: Andreas
full_name: Wallraff, Andreas
last_name: Wallraff
citation:
ama: Filipp S, Maurer P, Leek P, et al. Two-qubit state tomography using a joint
dispersive readout. Physical Review Letters. 2009;102(20). doi:10.1103/PhysRevLett.102.200402
apa: Filipp, S., Maurer, P., Leek, P., Baur, M., Bianchetti, R., Fink, J. M., …
Wallraff, A. (2009). Two-qubit state tomography using a joint dispersive readout.
Physical Review Letters. American Physical Society. https://doi.org/10.1103/PhysRevLett.102.200402
chicago: Filipp, Stefan, Patrick Maurer, Peter Leek, Matthias Baur, R Bianchetti,
Johannes M Fink, M Göppl, et al. “Two-Qubit State Tomography Using a Joint Dispersive
Readout.” Physical Review Letters. American Physical Society, 2009. https://doi.org/10.1103/PhysRevLett.102.200402.
ieee: S. Filipp et al., “Two-qubit state tomography using a joint dispersive
readout,” Physical Review Letters, vol. 102, no. 20. American Physical
Society, 2009.
ista: Filipp S, Maurer P, Leek P, Baur M, Bianchetti R, Fink JM, Göppl M, Steffen
L, Gambetta J, Blais A, Wallraff A. 2009. Two-qubit state tomography using a joint
dispersive readout. Physical Review Letters. 102(20).
mla: Filipp, Stefan, et al. “Two-Qubit State Tomography Using a Joint Dispersive
Readout.” Physical Review Letters, vol. 102, no. 20, American Physical
Society, 2009, doi:10.1103/PhysRevLett.102.200402.
short: S. Filipp, P. Maurer, P. Leek, M. Baur, R. Bianchetti, J.M. Fink, M. Göppl,
L. Steffen, J. Gambetta, A. Blais, A. Wallraff, Physical Review Letters 102 (2009).
date_created: 2018-12-11T11:53:54Z
date_published: 2009-05-18T00:00:00Z
date_updated: 2021-01-12T06:53:04Z
day: '18'
doi: 10.1103/PhysRevLett.102.200402
extern: 1
intvolume: ' 102'
issue: '20'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/0812.2485
month: '05'
oa: 1
publication: Physical Review Letters
publication_status: published
publisher: American Physical Society
publist_id: '5353'
quality_controlled: 0
status: public
title: Two-qubit state tomography using a joint dispersive readout
type: journal_article
volume: 102
year: '2009'
...
---
_id: '1769'
abstract:
- lang: eng
text: We present an ideal realization of the Tavis-Cummings model in the absence
of atom number and coupling fluctuations by embedding a discrete number of fully
controllable superconducting qubits at fixed positions into a transmission line
resonator. Measuring the vacuum Rabi mode splitting with one, two, and three qubits
strongly coupled to the cavity field, we explore both bright and dark dressed
collective multiqubit states and observe the discrete N scaling of the collective
dipole coupling strength. Our experiments demonstrate a novel approach to explore
collective states, such as the W state, in a fully globally and locally controllable
quantum system. Our scalable approach is interesting for solid-state quantum information
processing and for fundamental multiatom quantum optics experiments with fixed
atom numbers.
acknowledgement: This work was supported by SNF Grant No. 200021-111899 and ETHZ.
P. J. L. was supported by the EU with a MC-EIF. A. B. was supported by NSERC, CIFAR,
and the Alfred P. Sloan Foundation
author:
- first_name: Johannes M
full_name: Johannes Fink
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
- first_name: R
full_name: Bianchetti, R
last_name: Bianchetti
- first_name: Matthias
full_name: Baur, Matthias P
last_name: Baur
- first_name: M
full_name: Göppl, M
last_name: Göppl
- first_name: L.
full_name: Steffen, L. Kraig
last_name: Steffen
- first_name: Stefan
full_name: Filipp, Stefan
last_name: Filipp
- first_name: Peter
full_name: Leek, Peter J
last_name: Leek
- first_name: Alexandre
full_name: Blais, Alexandre
last_name: Blais
- first_name: Andreas
full_name: Wallraff, Andreas
last_name: Wallraff
citation:
ama: Fink JM, Bianchetti R, Baur M, et al. Dressed collective qubit states and the
Tavis-Cummings model in circuit QED. Physical Review Letters. 2009;103(8).
doi:10.1103/PhysRevLett.103.083601
apa: Fink, J. M., Bianchetti, R., Baur, M., Göppl, M., Steffen, L., Filipp, S.,
… Wallraff, A. (2009). Dressed collective qubit states and the Tavis-Cummings
model in circuit QED. Physical Review Letters. American Physical Society.
https://doi.org/10.1103/PhysRevLett.103.083601
chicago: Fink, Johannes M, R Bianchetti, Matthias Baur, M Göppl, L. Steffen, Stefan
Filipp, Peter Leek, Alexandre Blais, and Andreas Wallraff. “Dressed Collective
Qubit States and the Tavis-Cummings Model in Circuit QED.” Physical Review
Letters. American Physical Society, 2009. https://doi.org/10.1103/PhysRevLett.103.083601.
ieee: J. M. Fink et al., “Dressed collective qubit states and the Tavis-Cummings
model in circuit QED,” Physical Review Letters, vol. 103, no. 8. American
Physical Society, 2009.
ista: Fink JM, Bianchetti R, Baur M, Göppl M, Steffen L, Filipp S, Leek P, Blais
A, Wallraff A. 2009. Dressed collective qubit states and the Tavis-Cummings model
in circuit QED. Physical Review Letters. 103(8).
mla: Fink, Johannes M., et al. “Dressed Collective Qubit States and the Tavis-Cummings
Model in Circuit QED.” Physical Review Letters, vol. 103, no. 8, American
Physical Society, 2009, doi:10.1103/PhysRevLett.103.083601.
short: J.M. Fink, R. Bianchetti, M. Baur, M. Göppl, L. Steffen, S. Filipp, P. Leek,
A. Blais, A. Wallraff, Physical Review Letters 103 (2009).
date_created: 2018-12-11T11:53:55Z
date_published: 2009-08-17T00:00:00Z
date_updated: 2021-01-12T06:53:05Z
day: '17'
doi: 10.1103/PhysRevLett.103.083601
extern: 1
intvolume: ' 103'
issue: '8'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/0812.2651
month: '08'
oa: 1
publication: Physical Review Letters
publication_status: published
publisher: American Physical Society
publist_id: '5350'
quality_controlled: 0
status: public
title: Dressed collective qubit states and the Tavis-Cummings model in circuit QED
type: journal_article
volume: 103
year: '2009'
...
---
_id: '1770'
abstract:
- lang: eng
text: The quantum state of a superconducting qubit nonresonantly coupled to a transmission
line resonator can be determined by measuring the quadrature amplitudes of an
electromagnetic field transmitted through the resonator. We present experiments
in which we analyze in detail the dynamics of the transmitted field as a function
of the measurement frequency for both weak continuous and pulsed measurements.
We find excellent agreement between our data and calculations based on a set of
Bloch-type differential equations for the cavity field derived from the dispersive
Jaynes-Cummings Hamiltonian including dissipation. We show that the measured system
response can be used to construct a measurement operator from which the qubit
population can be inferred accurately. Such a measurement operator can be used
in tomographic methods to reconstruct single and multiqubit states in ensemble-averaged
measurements.
acknowledgement: This work was supported by the SNF Project No. 111899 and ETH Zurich.
A.B. was supported by NSERC, CIFAR, and the Alfred P. Sloan Foundation
author:
- first_name: R
full_name: Bianchetti, R
last_name: Bianchetti
- first_name: Stefan
full_name: Filipp, Stefan
last_name: Filipp
- first_name: Matthias
full_name: Baur, Matthias P
last_name: Baur
- first_name: Johannes M
full_name: Johannes Fink
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
- first_name: M
full_name: Göppl, M
last_name: Göppl
- first_name: Peter
full_name: Leek, Peter J
last_name: Leek
- first_name: L.
full_name: Steffen, L. Kraig
last_name: Steffen
- first_name: Alexandre
full_name: Blais, Alexandre
last_name: Blais
- first_name: Andreas
full_name: Wallraff, Andreas
last_name: Wallraff
citation:
ama: Bianchetti R, Filipp S, Baur M, et al. Dynamics of dispersive single-qubit
readout in circuit quantum electrodynamics. Physical Review A - Atomic, Molecular,
and Optical Physics. 2009;80(4). doi:10.1103/PhysRevA.80.043840
apa: Bianchetti, R., Filipp, S., Baur, M., Fink, J. M., Göppl, M., Leek, P., … Wallraff,
A. (2009). Dynamics of dispersive single-qubit readout in circuit quantum electrodynamics.
Physical Review A - Atomic, Molecular, and Optical Physics. American Physical
Society. https://doi.org/10.1103/PhysRevA.80.043840
chicago: Bianchetti, R, Stefan Filipp, Matthias Baur, Johannes M Fink, M Göppl,
Peter Leek, L. Steffen, Alexandre Blais, and Andreas Wallraff. “Dynamics of Dispersive
Single-Qubit Readout in Circuit Quantum Electrodynamics.” Physical Review A
- Atomic, Molecular, and Optical Physics. American Physical Society, 2009.
https://doi.org/10.1103/PhysRevA.80.043840.
ieee: R. Bianchetti et al., “Dynamics of dispersive single-qubit readout
in circuit quantum electrodynamics,” Physical Review A - Atomic, Molecular,
and Optical Physics, vol. 80, no. 4. American Physical Society, 2009.
ista: Bianchetti R, Filipp S, Baur M, Fink JM, Göppl M, Leek P, Steffen L, Blais
A, Wallraff A. 2009. Dynamics of dispersive single-qubit readout in circuit quantum
electrodynamics. Physical Review A - Atomic, Molecular, and Optical Physics. 80(4).
mla: Bianchetti, R., et al. “Dynamics of Dispersive Single-Qubit Readout in Circuit
Quantum Electrodynamics.” Physical Review A - Atomic, Molecular, and Optical
Physics, vol. 80, no. 4, American Physical Society, 2009, doi:10.1103/PhysRevA.80.043840.
short: R. Bianchetti, S. Filipp, M. Baur, J.M. Fink, M. Göppl, P. Leek, L. Steffen,
A. Blais, A. Wallraff, Physical Review A - Atomic, Molecular, and Optical Physics
80 (2009).
date_created: 2018-12-11T11:53:55Z
date_published: 2009-10-30T00:00:00Z
date_updated: 2021-01-12T06:53:05Z
day: '30'
doi: 10.1103/PhysRevA.80.043840
extern: 1
intvolume: ' 80'
issue: '4'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/0907.2549
month: '10'
oa: 1
publication: Physical Review A - Atomic, Molecular, and Optical Physics
publication_status: published
publisher: American Physical Society
publist_id: '5349'
quality_controlled: 0
status: public
title: Dynamics of dispersive single-qubit readout in circuit quantum electrodynamics
type: journal_article
volume: 80
year: '2009'
...
---
_id: '1771'
abstract:
- lang: eng
text: The exceptionally strong coupling realizable between superconducting qubits
and photons stored in an on-chip microwave resonator allows for the detailed study
of matter-light interactions in the realm of circuit quantum electrodynamics (QED).
Here we investigate the resonant interaction between a single transmon-type multilevel
artificial atom and weak thermal and coherent fields. We explore up to three photon
dressed states of the coupled system in a linear response heterodyne transmission
measurement. The results are in good quantitative agreement with a generalized
Jaynes-Cummings model. Our data indicate that the role of thermal fields in resonant
cavity QED can be studied in detail using superconducting circuits.
acknowledgement: Nobel Foundation
author:
- first_name: Johannes M
full_name: Johannes Fink
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
- first_name: Matthias
full_name: Baur, Matthias P
last_name: Baur
- first_name: R
full_name: Bianchetti, R
last_name: Bianchetti
- first_name: Stefan
full_name: Filipp, Stefan
last_name: Filipp
- first_name: M
full_name: Göppl, M
last_name: Göppl
- first_name: Peter
full_name: Leek, Peter J
last_name: Leek
- first_name: L.
full_name: Steffen, L. Kraig
last_name: Steffen
- first_name: Alexandre
full_name: Blais, Alexandre
last_name: Blais
- first_name: Andreas
full_name: Wallraff, Andreas
last_name: Wallraff
citation:
ama: Fink JM, Baur M, Bianchetti R, et al. Thermal excitation of multi-photon dressed
states in circuit quantum electrodynamics. Physica Scripta T. 2009;T137.
doi:10.1088/0031-8949/2009/T137/014013
apa: Fink, J. M., Baur, M., Bianchetti, R., Filipp, S., Göppl, M., Leek, P., … Wallraff,
A. (2009). Thermal excitation of multi-photon dressed states in circuit quantum
electrodynamics. Physica Scripta T. IOP Publishing Ltd. https://doi.org/10.1088/0031-8949/2009/T137/014013
chicago: Fink, Johannes M, Matthias Baur, R Bianchetti, Stefan Filipp, M Göppl,
Peter Leek, L. Steffen, Alexandre Blais, and Andreas Wallraff. “Thermal Excitation
of Multi-Photon Dressed States in Circuit Quantum Electrodynamics.” Physica
Scripta T. IOP Publishing Ltd., 2009. https://doi.org/10.1088/0031-8949/2009/T137/014013.
ieee: J. M. Fink et al., “Thermal excitation of multi-photon dressed states
in circuit quantum electrodynamics,” Physica Scripta T, vol. T137. IOP
Publishing Ltd., 2009.
ista: Fink JM, Baur M, Bianchetti R, Filipp S, Göppl M, Leek P, Steffen L, Blais
A, Wallraff A. 2009. Thermal excitation of multi-photon dressed states in circuit
quantum electrodynamics. Physica Scripta T. T137.
mla: Fink, Johannes M., et al. “Thermal Excitation of Multi-Photon Dressed States
in Circuit Quantum Electrodynamics.” Physica Scripta T, vol. T137, IOP
Publishing Ltd., 2009, doi:10.1088/0031-8949/2009/T137/014013.
short: J.M. Fink, M. Baur, R. Bianchetti, S. Filipp, M. Göppl, P. Leek, L. Steffen,
A. Blais, A. Wallraff, Physica Scripta T T137 (2009).
date_created: 2018-12-11T11:53:55Z
date_published: 2009-01-01T00:00:00Z
date_updated: 2021-01-12T06:53:06Z
day: '01'
doi: 10.1088/0031-8949/2009/T137/014013
extern: 1
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/0911.3797
month: '01'
oa: 1
publication: Physica Scripta T
publication_status: published
publisher: IOP Publishing Ltd.
publist_id: '5348'
quality_controlled: 0
status: public
title: Thermal excitation of multi-photon dressed states in circuit quantum electrodynamics
type: journal_article
volume: T137
year: '2009'
...
---
_id: '1798'
abstract:
- lang: eng
text: The mammalian brain is assembled from thousands of neuronal cell types that
are organized in distinct circuits to perform behaviorally relevant computations.
Transgenic mouse lines with selectively marked cell types would facilitate our
ability to dissect functional components of complex circuits. We carried out a
screen for cell type-specific green fluorescent protein expression in the retina
using BAC transgenic mice from the GENSAT project. Among others, we identified
mouse lines in which the inhibitory cell types of the night vision and directional
selective circuit were selectively labeled. We quantified the stratification patterns
to predict potential synaptic connectivity between marked cells of different lines
and found that some of the lines enabled targeted recordings and imaging of cell
types from developing or mature retinal circuits. Our results suggest the potential
use of a stratification-based screening approach for characterizing neuronal circuitry
in other layered brain structures, such as the neocortex.
acknowledgement: This study was supported by Friedrich Miescher Institute funds, a
US Office of Naval Research Naval International Cooperative Opportunities in Science
and Technology Program grant, a Marie Curie Excellence grant, a National Center
for Competence in Research in Genetics grant and a European Union HEALTH-F2-223156
grant to B.R., and by National Institute of Neurological Disorders and Stroke contracts
N01NS02331 and HHSN271200723701C to N.H.
author:
- first_name: Sandra
full_name: Sandra Siegert
id: 36ACD32E-F248-11E8-B48F-1D18A9856A87
last_name: Siegert
orcid: 0000-0001-8635-0877
- first_name: Brigitte
full_name: Scherf, Brigitte G
last_name: Scherf
- first_name: Karina
full_name: Del Punta, Karina
last_name: Del Punta
- first_name: Nick
full_name: Didkovsky, Nick
last_name: Didkovsky
- first_name: Nathaniel
full_name: Heintz, Nathaniel M
last_name: Heintz
- first_name: Botond
full_name: Roska, Botond M
last_name: Roska
citation:
ama: Siegert S, Scherf B, Del Punta K, Didkovsky N, Heintz N, Roska B. Genetic address
book for retinal cell types. Nature Neuroscience. 2009;12(9):1197-1204.
doi:10.1038/nn.2370
apa: Siegert, S., Scherf, B., Del Punta, K., Didkovsky, N., Heintz, N., & Roska,
B. (2009). Genetic address book for retinal cell types. Nature Neuroscience.
Nature Publishing Group. https://doi.org/10.1038/nn.2370
chicago: Siegert, Sandra, Brigitte Scherf, Karina Del Punta, Nick Didkovsky, Nathaniel
Heintz, and Botond Roska. “Genetic Address Book for Retinal Cell Types.” Nature
Neuroscience. Nature Publishing Group, 2009. https://doi.org/10.1038/nn.2370.
ieee: S. Siegert, B. Scherf, K. Del Punta, N. Didkovsky, N. Heintz, and B. Roska,
“Genetic address book for retinal cell types,” Nature Neuroscience, vol.
12, no. 9. Nature Publishing Group, pp. 1197–1204, 2009.
ista: Siegert S, Scherf B, Del Punta K, Didkovsky N, Heintz N, Roska B. 2009. Genetic
address book for retinal cell types. Nature Neuroscience. 12(9), 1197–1204.
mla: Siegert, Sandra, et al. “Genetic Address Book for Retinal Cell Types.” Nature
Neuroscience, vol. 12, no. 9, Nature Publishing Group, 2009, pp. 1197–204,
doi:10.1038/nn.2370.
short: S. Siegert, B. Scherf, K. Del Punta, N. Didkovsky, N. Heintz, B. Roska, Nature
Neuroscience 12 (2009) 1197–1204.
date_created: 2018-12-11T11:54:04Z
date_published: 2009-09-01T00:00:00Z
date_updated: 2021-01-12T06:53:16Z
day: '01'
doi: 10.1038/nn.2370
extern: 1
intvolume: ' 12'
issue: '9'
month: '09'
page: 1197 - 1204
publication: Nature Neuroscience
publication_status: published
publisher: Nature Publishing Group
publist_id: '5312'
quality_controlled: 0
status: public
title: Genetic address book for retinal cell types
type: journal_article
volume: 12
year: '2009'
...
---
_id: '1799'
abstract:
- lang: eng
text: 'The detection of approaching objects, such as looming predators, is necessary
for survival. Which neurons and circuits mediate this function? We combined genetic
labeling of cell types, two-photon microscopy, electrophysiology and theoretical
modeling to address this question. We identify an approach-sensitive ganglion
cell type in the mouse retina, resolve elements of its afferent neural circuit,
and describe how these confer approach sensitivity on the ganglion cell. The circuit''s
essential building block is a rapid inhibitory pathway: it selectively suppresses
responses to non-approaching objects. This rapid inhibitory pathway, which includes
AII amacrine cells connected to bipolar cells through electrical synapses, was
previously described in the context of night-time vision. In the daytime conditions
of our experiments, the same pathway conveys signals in the reverse direction.
The dual use of a neural pathway in different physiological conditions illustrates
the efficiency with which several functions can be accommodated in a single circuit.'
acknowledgement: The study was supported by Friedrich Miescher Institute funds, a
US Office of Naval Research Naval International Cooperative Opportunities in Science
and Technology program grant, a Marie Curie Excellence Grant, a Human Frontier Science
Program Young Investigator grant, a National Centers of Competence in Research in
Genetics grant and a European Union HEALTH-F2-223156 grant to B.R., a Marie Curie
Postdoctoral Fellowship to T.A.M., the Centre National de la Recherche Scientifique
through the Unité Mixte de Recherche 8550 to R.A.d.S.
author:
- first_name: Thomas
full_name: Münch, Thomas A
last_name: Münch
- first_name: Ravá
full_name: Da Silveira, Ravá A
last_name: Da Silveira
- first_name: Sandra
full_name: Sandra Siegert
id: 36ACD32E-F248-11E8-B48F-1D18A9856A87
last_name: Siegert
orcid: 0000-0001-8635-0877
- first_name: Tim
full_name: Viney, Tim J
last_name: Viney
- first_name: Gautam
full_name: Awatramani, Gautam B
last_name: Awatramani
- first_name: Botond
full_name: Roska, Botond M
last_name: Roska
citation:
ama: Münch T, Da Silveira R, Siegert S, Viney T, Awatramani G, Roska B. Approach
sensitivity in the retina processed by a multifunctional neural circuit. Nature
Neuroscience. 2009;12(10):1308-1316. doi:10.1038/nn.2389
apa: Münch, T., Da Silveira, R., Siegert, S., Viney, T., Awatramani, G., & Roska,
B. (2009). Approach sensitivity in the retina processed by a multifunctional neural
circuit. Nature Neuroscience. Nature Publishing Group. https://doi.org/10.1038/nn.2389
chicago: Münch, Thomas, Ravá Da Silveira, Sandra Siegert, Tim Viney, Gautam Awatramani,
and Botond Roska. “Approach Sensitivity in the Retina Processed by a Multifunctional
Neural Circuit.” Nature Neuroscience. Nature Publishing Group, 2009. https://doi.org/10.1038/nn.2389.
ieee: T. Münch, R. Da Silveira, S. Siegert, T. Viney, G. Awatramani, and B. Roska,
“Approach sensitivity in the retina processed by a multifunctional neural circuit,”
Nature Neuroscience, vol. 12, no. 10. Nature Publishing Group, pp. 1308–1316,
2009.
ista: Münch T, Da Silveira R, Siegert S, Viney T, Awatramani G, Roska B. 2009. Approach
sensitivity in the retina processed by a multifunctional neural circuit. Nature
Neuroscience. 12(10), 1308–1316.
mla: Münch, Thomas, et al. “Approach Sensitivity in the Retina Processed by a Multifunctional
Neural Circuit.” Nature Neuroscience, vol. 12, no. 10, Nature Publishing
Group, 2009, pp. 1308–16, doi:10.1038/nn.2389.
short: T. Münch, R. Da Silveira, S. Siegert, T. Viney, G. Awatramani, B. Roska,
Nature Neuroscience 12 (2009) 1308–1316.
date_created: 2018-12-11T11:54:04Z
date_published: 2009-10-01T00:00:00Z
date_updated: 2021-01-12T06:53:16Z
day: '01'
doi: 10.1038/nn.2389
extern: 1
intvolume: ' 12'
issue: '10'
month: '10'
page: 1308 - 1316
publication: Nature Neuroscience
publication_status: published
publisher: Nature Publishing Group
publist_id: '5311'
quality_controlled: 0
status: public
title: Approach sensitivity in the retina processed by a multifunctional neural circuit
type: journal_article
volume: 12
year: '2009'
...
---
_id: '1825'
abstract:
- lang: eng
text: 'Many membrane channels and receptors exhibit adaptive, or desensitized, response
to a strong sustained input stimulus. A key mechanism that underlies this response
is the slow, activity-dependent removal of responding molecules to a pool which
is unavailable to respond immediately to the input. This mechanism is implemented
in different ways in various biological systems and has traditionally been studied
separately for each. Here we highlight the common aspects of this principle, shared
by many biological systems, and suggest a unifying theoretical framework. We study
theoretically a class of models which describes the general mechanism and allows
us to distinguish its universal from system-specific features. We show that under
general conditions, regardless of the details of kinetics, molecule availability
encodes an averaging over past activity and feeds back multiplicatively on the
system output. The kinetics of recovery from unavailability determines the effective
memory kernel inside the feedback branch, giving rise to a variety of system-specific
forms of adaptive response—precise or input-dependent, exponential or power-law—as
special cases of the same model. '
author:
- first_name: Tamar
full_name: Tamar Friedlander
id: 36A5845C-F248-11E8-B48F-1D18A9856A87
last_name: Friedlander
- first_name: Naama
full_name: Brenner, Naama
last_name: Brenner
citation:
ama: Friedlander T, Brenner N. Adaptive response by state-dependent inactivation.
PNAS. 2009;106(52):22558-22563. doi:10.1073/pnas.0902146106
apa: Friedlander, T., & Brenner, N. (2009). Adaptive response by state-dependent
inactivation. PNAS. National Academy of Sciences. https://doi.org/10.1073/pnas.0902146106
chicago: Friedlander, Tamar, and Naama Brenner. “Adaptive Response by State-Dependent
Inactivation.” PNAS. National Academy of Sciences, 2009. https://doi.org/10.1073/pnas.0902146106 .
ieee: T. Friedlander and N. Brenner, “Adaptive response by state-dependent inactivation,”
PNAS, vol. 106, no. 52. National Academy of Sciences, pp. 22558–22563,
2009.
ista: Friedlander T, Brenner N. 2009. Adaptive response by state-dependent inactivation.
PNAS. 106(52), 22558–22563.
mla: Friedlander, Tamar, and Naama Brenner. “Adaptive Response by State-Dependent
Inactivation.” PNAS, vol. 106, no. 52, National Academy of Sciences, 2009,
pp. 22558–63, doi:10.1073/pnas.0902146106
.
short: T. Friedlander, N. Brenner, PNAS 106 (2009) 22558–22563.
date_created: 2018-12-11T11:54:13Z
date_published: 2009-12-01T00:00:00Z
date_updated: 2021-01-12T06:53:26Z
day: '01'
doi: '10.1073/pnas.0902146106 '
extern: 1
intvolume: ' 106'
issue: '52'
main_file_link:
- open_access: '1'
url: http://www.pnas.org/content/106/52/22558.full.pdf
month: '12'
oa: 1
page: 22558 - 22563
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '5281'
quality_controlled: 0
status: public
title: Adaptive response by state-dependent inactivation
type: journal_article
volume: 106
year: '2009'
...
---
_id: '1971'
abstract:
- lang: eng
text: Complex I plays a central role in cellular energy production, coupling electron
transfer between NADH and quinone to proton translocation. The mechanism of this
highly efficient enzyme is currently unknown. Mitochondrial complex I is a major
source of reactive oxygen species, which may be one of the causes of aging. Dysfunction
of complex I is implicated in many human neurodegenerative diseases. We have determined
several x-ray structures of the oxidized and reduced hydrophilic domain of complex
I from Thermus thermophilus at up to 3.1 Å resolution. The structures reveal the
mode of interaction of complex I with NADH, explaining known kinetic data and
providing implications for the mechanism of reactive oxygen species production
at the flavin site of complex I. Bound metals were identified in the channel at
the interface with the frataxin-like subunit Nqo15, indicating possible iron-binding
sites. Conformational changes upon reduction of the complex involve adjustments
in the nucleotide-binding pocket, as well as small but significant shifts of several
α-helices at the interface with the membrane domain. These shifts are likely to
be driven by the reduction of nearby iron-sulfur clusters N2 and N6a/b. Cluster
N2 is the electron donor to quinone and is coordinated by unique motif involving
two consecutive (tandem) cysteines. An unprecedented "on/off switch"
(disconnection) of coordinating bonds between the tandem cysteines and this cluster
was observed upon reduction. Comparison of the structures suggests a novel mechanism
of coupling between electron transfer and proton translocation, combining conformational
changes and protonation/deprotonation of tandem cysteines.
acknowledgement: 'This work was supported by the Medical Research Council. '
author:
- first_name: John
full_name: Berrisford, John M
last_name: Berrisford
- first_name: Leonid A
full_name: Leonid Sazanov
id: 338D39FE-F248-11E8-B48F-1D18A9856A87
last_name: Sazanov
orcid: 0000-0002-0977-7989
citation:
ama: Berrisford J, Sazanov LA. Structural basis for the mechanism of respiratory
complex I. Journal of Biological Chemistry. 2009;284(43):29773-29783. doi:10.1074/jbc.M109.032144
apa: Berrisford, J., & Sazanov, L. A. (2009). Structural basis for the mechanism
of respiratory complex I. Journal of Biological Chemistry. American Society
for Biochemistry and Molecular Biology. https://doi.org/10.1074/jbc.M109.032144
chicago: Berrisford, John, and Leonid A Sazanov. “Structural Basis for the Mechanism
of Respiratory Complex I.” Journal of Biological Chemistry. American Society
for Biochemistry and Molecular Biology, 2009. https://doi.org/10.1074/jbc.M109.032144.
ieee: J. Berrisford and L. A. Sazanov, “Structural basis for the mechanism of respiratory
complex I,” Journal of Biological Chemistry, vol. 284, no. 43. American
Society for Biochemistry and Molecular Biology, pp. 29773–29783, 2009.
ista: Berrisford J, Sazanov LA. 2009. Structural basis for the mechanism of respiratory
complex I. Journal of Biological Chemistry. 284(43), 29773–29783.
mla: Berrisford, John, and Leonid A. Sazanov. “Structural Basis for the Mechanism
of Respiratory Complex I.” Journal of Biological Chemistry, vol. 284, no.
43, American Society for Biochemistry and Molecular Biology, 2009, pp. 29773–83,
doi:10.1074/jbc.M109.032144.
short: J. Berrisford, L.A. Sazanov, Journal of Biological Chemistry 284 (2009) 29773–29783.
date_created: 2018-12-11T11:54:59Z
date_published: 2009-10-23T00:00:00Z
date_updated: 2021-01-12T06:54:26Z
day: '23'
doi: 10.1074/jbc.M109.032144
extern: 1
intvolume: ' 284'
issue: '43'
month: '10'
page: 29773 - 29783
publication: Journal of Biological Chemistry
publication_status: published
publisher: American Society for Biochemistry and Molecular Biology
publist_id: '5114'
quality_controlled: 0
status: public
title: Structural basis for the mechanism of respiratory complex I
type: journal_article
volume: 284
year: '2009'
...