---
_id: '3203'
abstract:
- lang: eng
  text: In recent years the Markov Random Field (MRF) has become the de facto probabilistic
    model for low-level vision applications. However, in a maximum a posteriori (MAP)
    framework, MRFs inherently encourage delta function marginal statistics. By contrast,
    many low-level vision problems have heavy tailed marginal statistics, making the
    MRF model unsuitable. In this paper we introduce a more general Marginal Probability
    Field (MPF), of which the MRF is a special, linear case, and show that convex
    energy MPFs can be used to encourage arbitrary marginal statistics. We introduce
    a flexible, extensible framework for effectively optimizing the resulting NP-hard
    MAP problem, based around dual-decomposition and a modified mincost flow algorithm,
    and which achieves global optimality in some instances. We use a range of applications,
    including image denoising and texture synthesis, to demonstrate the benefits of
    this class of MPF over MRFs.
author:
- first_name: Oliver
  full_name: Woodford, Oliver J
  last_name: Woodford
- first_name: Carsten
  full_name: Rother, Carsten
  last_name: Rother
- first_name: Vladimir
  full_name: Vladimir Kolmogorov
  id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
  last_name: Kolmogorov
citation:
  ama: 'Woodford O, Rother C, Kolmogorov V. A global perspective on MAP inference
    for low level vision. In: IEEE; 2009:2319-2326. doi:<a href="https://doi.org/10.1109/ICCV.2009.5459434">10.1109/ICCV.2009.5459434</a>'
  apa: 'Woodford, O., Rother, C., &#38; Kolmogorov, V. (2009). A global perspective
    on MAP inference for low level vision (pp. 2319–2326). Presented at the ICCV:
    International Conference on Computer Vision, IEEE. <a href="https://doi.org/10.1109/ICCV.2009.5459434">https://doi.org/10.1109/ICCV.2009.5459434</a>'
  chicago: Woodford, Oliver, Carsten Rother, and Vladimir Kolmogorov. “A Global Perspective
    on MAP Inference for Low Level Vision,” 2319–26. IEEE, 2009. <a href="https://doi.org/10.1109/ICCV.2009.5459434">https://doi.org/10.1109/ICCV.2009.5459434</a>.
  ieee: 'O. Woodford, C. Rother, and V. Kolmogorov, “A global perspective on MAP inference
    for low level vision,” presented at the ICCV: International Conference on Computer
    Vision, 2009, pp. 2319–2326.'
  ista: 'Woodford O, Rother C, Kolmogorov V. 2009. A global perspective on MAP inference
    for low level vision. ICCV: International Conference on Computer Vision, 2319–2326.'
  mla: Woodford, Oliver, et al. <i>A Global Perspective on MAP Inference for Low Level
    Vision</i>. IEEE, 2009, pp. 2319–26, doi:<a href="https://doi.org/10.1109/ICCV.2009.5459434">10.1109/ICCV.2009.5459434</a>.
  short: O. Woodford, C. Rother, V. Kolmogorov, in:, IEEE, 2009, pp. 2319–2326.
conference:
  name: 'ICCV: International Conference on Computer Vision'
date_created: 2018-12-11T12:01:59Z
date_published: 2009-05-01T00:00:00Z
date_updated: 2021-01-12T07:41:46Z
day: '01'
doi: 10.1109/ICCV.2009.5459434
extern: 1
month: '05'
page: 2319 - 2326
publication_status: published
publisher: IEEE
publist_id: '3481'
quality_controlled: 0
status: public
title: A global perspective on MAP inference for low level vision
type: conference
year: '2009'
...
---
_id: '3230'
abstract:
- lang: eng
  text: 'We present a new approach to the design of IND-CCA2 secure hybrid encryption
    schemes in the standard model. Our approach provides an efficient generic transformation
    from 1-universal to 2-universal hash proof systems. The transformation involves
    a randomness extractor based on a 4-wise independent hash function as the key
    derivation function. Our methodology can be instantiated with efficient schemes
    based on standard intractability assumptions such as Decisional Diffie-Hellman,
    Quadratic Residuosity, and Paillier''s Decisional Composite Residuosity. Interestingly,
    our framework also allows to prove IND-CCA2 security of a hybrid version of 1991''s
    Damgård''s ElGamal public-key encryption scheme under the DDH assumption. '
alternative_title:
- LNCS
author:
- first_name: Eike
  full_name: Kiltz, Eike
  last_name: Kiltz
- first_name: Krzysztof Z
  full_name: Krzysztof Pietrzak
  id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
  last_name: Pietrzak
  orcid: 0000-0002-9139-1654
- first_name: Martijn
  full_name: Stam, Martijn
  last_name: Stam
- first_name: Moti
  full_name: Yung, Moti
  last_name: Yung
citation:
  ama: 'Kiltz E, Pietrzak KZ, Stam M, Yung M. A new randomness extraction paradigm
    for hybrid encryption. In: Vol 5479. Springer; 2009:590-609. doi:<a href="https://doi.org/10.1007/978-3-642-01001-9_34">10.1007/978-3-642-01001-9_34</a>'
  apa: 'Kiltz, E., Pietrzak, K. Z., Stam, M., &#38; Yung, M. (2009). A new randomness
    extraction paradigm for hybrid encryption (Vol. 5479, pp. 590–609). Presented
    at the EUROCRYPT: Theory and Applications of Cryptographic Techniques, Springer.
    <a href="https://doi.org/10.1007/978-3-642-01001-9_34">https://doi.org/10.1007/978-3-642-01001-9_34</a>'
  chicago: Kiltz, Eike, Krzysztof Z Pietrzak, Martijn Stam, and Moti Yung. “A New
    Randomness Extraction Paradigm for Hybrid Encryption,” 5479:590–609. Springer,
    2009. <a href="https://doi.org/10.1007/978-3-642-01001-9_34">https://doi.org/10.1007/978-3-642-01001-9_34</a>.
  ieee: 'E. Kiltz, K. Z. Pietrzak, M. Stam, and M. Yung, “A new randomness extraction
    paradigm for hybrid encryption,” presented at the EUROCRYPT: Theory and Applications
    of Cryptographic Techniques, 2009, vol. 5479, pp. 590–609.'
  ista: 'Kiltz E, Pietrzak KZ, Stam M, Yung M. 2009. A new randomness extraction paradigm
    for hybrid encryption. EUROCRYPT: Theory and Applications of Cryptographic Techniques,
    LNCS, vol. 5479, 590–609.'
  mla: Kiltz, Eike, et al. <i>A New Randomness Extraction Paradigm for Hybrid Encryption</i>.
    Vol. 5479, Springer, 2009, pp. 590–609, doi:<a href="https://doi.org/10.1007/978-3-642-01001-9_34">10.1007/978-3-642-01001-9_34</a>.
  short: E. Kiltz, K.Z. Pietrzak, M. Stam, M. Yung, in:, Springer, 2009, pp. 590–609.
conference:
  name: 'EUROCRYPT: Theory and Applications of Cryptographic Techniques'
date_created: 2018-12-11T12:02:09Z
date_published: 2009-05-28T00:00:00Z
date_updated: 2021-01-12T07:41:58Z
day: '28'
doi: 10.1007/978-3-642-01001-9_34
extern: 1
intvolume: '      5479'
month: '05'
page: 590 - 609
publication_status: published
publisher: Springer
publist_id: '3449'
quality_controlled: 0
status: public
title: A new randomness extraction paradigm for hybrid encryption
type: conference
volume: 5479
year: '2009'
...
---
_id: '3231'
abstract:
- lang: eng
  text: 'We investigate the security of &quot;padding-based&quot; encryption schemes
    in the standard model. This class contains all public-key encryption schemes where
    the encryption algorithm first applies some invertible public transformation to
    the message (the &quot;padding&quot;), followed by a trapdoor permutation. In
    particular, this class contains OAEP and its variants. Our main result is a black-box
    impossibility result showing that one cannot prove any such padding-based scheme
    chosen-ciphertext secure even assuming the existence of ideal trapdoor permutations.
    The latter is a strong ideal abstraction of trapdoor permutations which inherits
    all security properties of uniform random permutations. '
alternative_title:
- LNCS
author:
- first_name: Eike
  full_name: Kiltz, Eike
  last_name: Kiltz
- first_name: Krzysztof Z
  full_name: Krzysztof Pietrzak
  id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
  last_name: Pietrzak
  orcid: 0000-0002-9139-1654
citation:
  ama: 'Kiltz E, Pietrzak KZ. On the security of padding based encryption schemes
    Why We cannot prove OAEP secure in the standard model. In: Vol 5479. Springer;
    2009:389-406. doi:<a href="https://doi.org/10.1007/978-3-642-01001-9_23">10.1007/978-3-642-01001-9_23</a>'
  apa: 'Kiltz, E., &#38; Pietrzak, K. Z. (2009). On the security of padding based
    encryption schemes Why We cannot prove OAEP secure in the standard model (Vol.
    5479, pp. 389–406). Presented at the EUROCRYPT: Theory and Applications of Cryptographic
    Techniques, Springer. <a href="https://doi.org/10.1007/978-3-642-01001-9_23">https://doi.org/10.1007/978-3-642-01001-9_23</a>'
  chicago: Kiltz, Eike, and Krzysztof Z Pietrzak. “On the Security of Padding Based
    Encryption Schemes Why We Cannot Prove OAEP Secure in the Standard Model,” 5479:389–406.
    Springer, 2009. <a href="https://doi.org/10.1007/978-3-642-01001-9_23">https://doi.org/10.1007/978-3-642-01001-9_23</a>.
  ieee: 'E. Kiltz and K. Z. Pietrzak, “On the security of padding based encryption
    schemes Why We cannot prove OAEP secure in the standard model,” presented at the
    EUROCRYPT: Theory and Applications of Cryptographic Techniques, 2009, vol. 5479,
    pp. 389–406.'
  ista: 'Kiltz E, Pietrzak KZ. 2009. On the security of padding based encryption schemes
    Why We cannot prove OAEP secure in the standard model. EUROCRYPT: Theory and Applications
    of Cryptographic Techniques, LNCS, vol. 5479, 389–406.'
  mla: Kiltz, Eike, and Krzysztof Z. Pietrzak. <i>On the Security of Padding Based
    Encryption Schemes Why We Cannot Prove OAEP Secure in the Standard Model</i>.
    Vol. 5479, Springer, 2009, pp. 389–406, doi:<a href="https://doi.org/10.1007/978-3-642-01001-9_23">10.1007/978-3-642-01001-9_23</a>.
  short: E. Kiltz, K.Z. Pietrzak, in:, Springer, 2009, pp. 389–406.
conference:
  name: 'EUROCRYPT: Theory and Applications of Cryptographic Techniques'
date_created: 2018-12-11T12:02:09Z
date_published: 2009-05-28T00:00:00Z
date_updated: 2021-01-12T07:41:58Z
day: '28'
doi: 10.1007/978-3-642-01001-9_23
extern: 1
intvolume: '      5479'
month: '05'
page: 389 - 406
publication_status: published
publisher: Springer
publist_id: '3450'
quality_controlled: 0
status: public
title: On the security of padding based encryption schemes Why We cannot prove OAEP
  secure in the standard model
type: conference
volume: 5479
year: '2009'
...
---
_id: '3232'
abstract:
- lang: eng
  text: 'A weak pseudorandom function (wPRF) is a cryptographic primitive similar
    to - but weaker than - a pseudorandom function: for wPRFs one only requires that
    the output is pseudorandom when queried on random inputs.We show that unlike &quot;normal&quot;
    PRFs, wPRFs are seedincompressible, in the sense that the output of a wPRF is
    pseudorandom even if a bounded amount of information about the key is leaked.
    As an application of this result we construct a simple mode of operation which
    - when instantiated with any wPRF - gives a leakage-resilient stream-cipher. The
    implementation of such a cipher is secure against every side-channel attack, as
    long as the amount of information leaked per round is bounded, but overall can
    be arbitrary large. The construction is simpler than the previous one (Dziembowski-Pietrzak
    FOCS''08) as it only uses a single primitive (a wPRF) in a straight forward manner. '
alternative_title:
- LNCS
author:
- first_name: Krzysztof Z
  full_name: Krzysztof Pietrzak
  id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
  last_name: Pietrzak
  orcid: 0000-0002-9139-1654
citation:
  ama: 'Pietrzak KZ. A leakage resilient mode of operation. In: Vol 5479. Springer;
    2009:462-482. doi:<a href="https://doi.org/10.1007/978-3-642-01001-9_27">10.1007/978-3-642-01001-9_27</a>'
  apa: 'Pietrzak, K. Z. (2009). A leakage resilient mode of operation (Vol. 5479,
    pp. 462–482). Presented at the CRYPTO: International Cryptology Conference, Springer.
    <a href="https://doi.org/10.1007/978-3-642-01001-9_27">https://doi.org/10.1007/978-3-642-01001-9_27</a>'
  chicago: Pietrzak, Krzysztof Z. “A Leakage Resilient Mode of Operation,” 5479:462–82.
    Springer, 2009. <a href="https://doi.org/10.1007/978-3-642-01001-9_27">https://doi.org/10.1007/978-3-642-01001-9_27</a>.
  ieee: 'K. Z. Pietrzak, “A leakage resilient mode of operation,” presented at the
    CRYPTO: International Cryptology Conference, 2009, vol. 5479, pp. 462–482.'
  ista: 'Pietrzak KZ. 2009. A leakage resilient mode of operation. CRYPTO: International
    Cryptology Conference, LNCS, vol. 5479, 462–482.'
  mla: Pietrzak, Krzysztof Z. <i>A Leakage Resilient Mode of Operation</i>. Vol. 5479,
    Springer, 2009, pp. 462–82, doi:<a href="https://doi.org/10.1007/978-3-642-01001-9_27">10.1007/978-3-642-01001-9_27</a>.
  short: K.Z. Pietrzak, in:, Springer, 2009, pp. 462–482.
conference:
  name: 'CRYPTO: International Cryptology Conference'
date_created: 2018-12-11T12:02:09Z
date_published: 2009-05-28T00:00:00Z
date_updated: 2021-01-12T07:41:59Z
day: '28'
doi: 10.1007/978-3-642-01001-9_27
extern: 1
intvolume: '      5479'
month: '05'
page: 462 - 482
publication_status: published
publisher: Springer
publist_id: '3448'
quality_controlled: 0
status: public
title: A leakage resilient mode of operation
type: conference
volume: 5479
year: '2009'
...
---
_id: '3292'
abstract:
- lang: eng
  text: Galactofuranose (Galf) containing molecules have been described at the cell
    surface of several eukaryotes and shown to contribute to the virulence of the
    parasite Leishmania major and the fungus Aspergillus fumigatus. It is anticipated
    that a number of the surface glycoconjugates such as N-glycans or glycolipids
    are galactofuranosylated in the Golgi apparatus. This raises the question of how
    the substrate for galactofuranosylation reactions, UDP-Galf, which is synthesized
    in the cytosol, translocates into the organelles of the secretory pathway. Here
    we report the first identification of a Golgi-localized nucleotide sugar transporter,
    named GlfB, with specificity for a UDP-Galf. In vitro transport assays established
    binding of UDP-Galf to GlfB and excluded transport of several other nucleotide
    sugars. Furthermore, the implication of glfB in the galactofuranosylation of A.
    fumigatus glycoconjugates and galactomannan was demonstrated by a targeted gene
    deletion approach. Our data reveal a direct connection between galactomannan and
    the organelles of the secretory pathway that strongly suggests that the cell wall-bound
    polysaccharide originates from its glycosylphosphatidylinositol-anchored form.
author:
- first_name: Jakob
  full_name: Engel, Jakob
  last_name: Engel
- first_name: Philipp S
  full_name: Schmalhorst, Philipp S
  id: 309D50DA-F248-11E8-B48F-1D18A9856A87
  last_name: Schmalhorst
  orcid: 0000-0002-5795-0133
- first_name: Thilo
  full_name: Dörk Bousset, Thilo
  last_name: Dörk Bousset
- first_name: Vincent
  full_name: Ferrières, Vincent
  last_name: Ferrières
- first_name: Françoise
  full_name: Routier, Françoise
  last_name: Routier
citation:
  ama: Engel J, Schmalhorst PS, Dörk Bousset T, Ferrières V, Routier F. A single UDP
    galactofuranose transporter is required for galactofuranosylation in Aspergillus
    fumigatus. <i>Journal of Biological Chemistry</i>. 2009;284(49):33859-33868. doi:<a
    href="https://doi.org/10.1074/jbc.M109.070219 ">10.1074/jbc.M109.070219 </a>
  apa: Engel, J., Schmalhorst, P. S., Dörk Bousset, T., Ferrières, V., &#38; Routier,
    F. (2009). A single UDP galactofuranose transporter is required for galactofuranosylation
    in Aspergillus fumigatus. <i>Journal of Biological Chemistry</i>. American Society
    for Biochemistry and Molecular Biology. <a href="https://doi.org/10.1074/jbc.M109.070219
    ">https://doi.org/10.1074/jbc.M109.070219 </a>
  chicago: Engel, Jakob, Philipp S Schmalhorst, Thilo Dörk Bousset, Vincent Ferrières,
    and Françoise Routier. “A Single UDP Galactofuranose Transporter Is Required for
    Galactofuranosylation in Aspergillus Fumigatus.” <i>Journal of Biological Chemistry</i>.
    American Society for Biochemistry and Molecular Biology, 2009. <a href="https://doi.org/10.1074/jbc.M109.070219
    ">https://doi.org/10.1074/jbc.M109.070219 </a>.
  ieee: J. Engel, P. S. Schmalhorst, T. Dörk Bousset, V. Ferrières, and F. Routier,
    “A single UDP galactofuranose transporter is required for galactofuranosylation
    in Aspergillus fumigatus,” <i>Journal of Biological Chemistry</i>, vol. 284, no.
    49. American Society for Biochemistry and Molecular Biology, pp. 33859–33868,
    2009.
  ista: Engel J, Schmalhorst PS, Dörk Bousset T, Ferrières V, Routier F. 2009. A single
    UDP galactofuranose transporter is required for galactofuranosylation in Aspergillus
    fumigatus. Journal of Biological Chemistry. 284(49), 33859–33868.
  mla: Engel, Jakob, et al. “A Single UDP Galactofuranose Transporter Is Required
    for Galactofuranosylation in Aspergillus Fumigatus.” <i>Journal of Biological
    Chemistry</i>, vol. 284, no. 49, American Society for Biochemistry and Molecular
    Biology, 2009, pp. 33859–68, doi:<a href="https://doi.org/10.1074/jbc.M109.070219
    ">10.1074/jbc.M109.070219 </a>.
  short: J. Engel, P.S. Schmalhorst, T. Dörk Bousset, V. Ferrières, F. Routier, Journal
    of Biological Chemistry 284 (2009) 33859–33868.
date_created: 2018-12-11T12:02:30Z
date_published: 2009-12-04T00:00:00Z
date_updated: 2021-01-12T07:42:26Z
day: '04'
doi: '10.1074/jbc.M109.070219 '
extern: '1'
intvolume: '       284'
issue: '49'
language:
- iso: eng
month: '12'
oa_version: None
page: 33859 - 33868
publication: Journal of Biological Chemistry
publication_status: published
publisher: American Society for Biochemistry and Molecular Biology
publist_id: '3353'
quality_controlled: '1'
status: public
title: A single UDP galactofuranose transporter is required for galactofuranosylation
  in Aspergillus fumigatus
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 284
year: '2009'
...
---
_id: '3293'
abstract:
- lang: eng
  text: Chemotactic responses of Drosophila to certain esters and alcohols are experience
    dependent. When the flies are exposed after eclosion to these chemicals, the odorants
    become strongly attractive. We show that behavioral conditioning is accompanied
    by an increase in the electrophysiological responses of single neurons in sensilla
    basiconica. Sensitization involves odorants that act on a common olfactory receptor.
    The possible mechanism of imaginal conditioning and its ecological and evolutionary
    significance are discussed.
author:
- first_name: Subhra
  full_name: Chakraborty Tuhin, Subhra
  last_name: Chakraborty Tuhin
- first_name: Sarit
  full_name: Sarit Goswami
  id: 3A578F32-F248-11E8-B48F-1D18A9856A87
  last_name: Goswami
- first_name: Obaid
  full_name: Siddiqi, Obaid
  last_name: Siddiqi
citation:
  ama: Chakraborty Tuhin S, Goswami S, Siddiqi O. Sensory correlates of imaginal conditioning
    in Drosophila melanogaster. <i>Journal of Neurogenetics</i>. 2009;23(1-2):210-219.
    doi:<a href="https://doi.org/10.1080/01677060802491559 ">10.1080/01677060802491559
    </a>
  apa: Chakraborty Tuhin, S., Goswami, S., &#38; Siddiqi, O. (2009). Sensory correlates
    of imaginal conditioning in Drosophila melanogaster. <i>Journal of Neurogenetics</i>.
    Informa Healthcare. <a href="https://doi.org/10.1080/01677060802491559 ">https://doi.org/10.1080/01677060802491559
    </a>
  chicago: Chakraborty Tuhin, Subhra, Sarit Goswami, and Obaid Siddiqi. “Sensory Correlates
    of Imaginal Conditioning in Drosophila Melanogaster.” <i>Journal of Neurogenetics</i>.
    Informa Healthcare, 2009. <a href="https://doi.org/10.1080/01677060802491559 ">https://doi.org/10.1080/01677060802491559
    </a>.
  ieee: S. Chakraborty Tuhin, S. Goswami, and O. Siddiqi, “Sensory correlates of imaginal
    conditioning in Drosophila melanogaster,” <i>Journal of Neurogenetics</i>, vol.
    23, no. 1–2. Informa Healthcare, pp. 210–9, 2009.
  ista: Chakraborty Tuhin S, Goswami S, Siddiqi O. 2009. Sensory correlates of imaginal
    conditioning in Drosophila melanogaster. Journal of Neurogenetics. 23(1–2), 210–9.
  mla: Chakraborty Tuhin, Subhra, et al. “Sensory Correlates of Imaginal Conditioning
    in Drosophila Melanogaster.” <i>Journal of Neurogenetics</i>, vol. 23, no. 1–2,
    Informa Healthcare, 2009, pp. 210–19, doi:<a href="https://doi.org/10.1080/01677060802491559
    ">10.1080/01677060802491559 </a>.
  short: S. Chakraborty Tuhin, S. Goswami, O. Siddiqi, Journal of Neurogenetics 23
    (2009) 210–9.
date_created: 2018-12-11T12:02:30Z
date_published: 2009-01-01T00:00:00Z
date_updated: 2021-01-12T07:42:27Z
day: '01'
doi: '10.1080/01677060802491559 '
extern: 1
intvolume: '        23'
issue: 1-2
month: '01'
page: 210 - 9
publication: Journal of Neurogenetics
publication_status: published
publisher: Informa Healthcare
publist_id: '3348'
quality_controlled: 0
status: public
title: Sensory correlates of imaginal conditioning in Drosophila melanogaster
type: journal_article
volume: 23
year: '2009'
...
---
_id: '3304'
abstract:
- lang: eng
  text: Complex traits often involve interactions between different genetic loci.
    This can lead to sign epistasis, whereby mutations that are individually deleterious
    or neutral combine to confer a fitness benefit. In order to acquire the beneficial
    genotype, an asexual population must cross a fitness valley or plateau by first
    acquiring the deleterious or neutral intermediates. Here, we present a complete,
    intuitive theoretical description of the valley-crossing process across the full
    spectrum of possible parameter regimes. We calculate the rate at which a population
    crosses a fitness valley or plateau of arbitrary width, as a function of the mutation
    rates, the population size, and the fitnesses of the intermediates. We find that
    when intermediates are close to neutral, a large population can cross even wide
    fitness valleys remarkably quickly, so that valley-crossing dynamics may be common
    even when mutations that directly increase fitness are also possible. Thus the
    evolutionary dynamics of large populations can be sensitive to the structure of
    an extended region of the fitness landscape — the population may not take directly
    uphill paths in favor of paths across valleys and plateaus that lead eventually
    to fitter genotypes. In smaller populations, we find that below a threshold size,
    which depends on the width of the fitness valley and the strength of selection
    against intermediate genotypes, valley-crossing is much less likely and hence
    the evolutionary dynamics are less influenced by distant regions of the fitness
    landscape.
author:
- first_name: Daniel
  full_name: Daniel Weissman
  id: 2D0CE020-F248-11E8-B48F-1D18A9856A87
  last_name: Weissman
- first_name: Michael
  full_name: Desai, Michael M
  last_name: Desai
- first_name: Daniel
  full_name: Fisher, Daniel S
  last_name: Fisher
- first_name: Marcus
  full_name: Feldman, Marcus W
  last_name: Feldman
citation:
  ama: Weissman D, Desai M, Fisher D, Feldman M. The rate at which asexual populations
    cross fitness valleys. <i>Theoretical Population Biology</i>. 2009;75(4):286-300.
    doi:<a href="https://doi.org/10.1016/j.tpb.2009.02.006">10.1016/j.tpb.2009.02.006</a>
  apa: Weissman, D., Desai, M., Fisher, D., &#38; Feldman, M. (2009). The rate at
    which asexual populations cross fitness valleys. <i>Theoretical Population Biology</i>.
    Academic Press. <a href="https://doi.org/10.1016/j.tpb.2009.02.006">https://doi.org/10.1016/j.tpb.2009.02.006</a>
  chicago: Weissman, Daniel, Michael Desai, Daniel Fisher, and Marcus Feldman. “The
    Rate at Which Asexual Populations Cross Fitness Valleys.” <i>Theoretical Population
    Biology</i>. Academic Press, 2009. <a href="https://doi.org/10.1016/j.tpb.2009.02.006">https://doi.org/10.1016/j.tpb.2009.02.006</a>.
  ieee: D. Weissman, M. Desai, D. Fisher, and M. Feldman, “The rate at which asexual
    populations cross fitness valleys,” <i>Theoretical Population Biology</i>, vol.
    75, no. 4. Academic Press, pp. 286–300, 2009.
  ista: Weissman D, Desai M, Fisher D, Feldman M. 2009. The rate at which asexual
    populations cross fitness valleys. Theoretical Population Biology. 75(4), 286–300.
  mla: Weissman, Daniel, et al. “The Rate at Which Asexual Populations Cross Fitness
    Valleys.” <i>Theoretical Population Biology</i>, vol. 75, no. 4, Academic Press,
    2009, pp. 286–300, doi:<a href="https://doi.org/10.1016/j.tpb.2009.02.006">10.1016/j.tpb.2009.02.006</a>.
  short: D. Weissman, M. Desai, D. Fisher, M. Feldman, Theoretical Population Biology
    75 (2009) 286–300.
date_created: 2018-12-11T12:02:34Z
date_published: 2009-06-01T00:00:00Z
date_updated: 2021-01-12T07:42:31Z
day: '01'
doi: 10.1016/j.tpb.2009.02.006
extern: 1
intvolume: '        75'
issue: '4'
month: '06'
page: 286 - 300
publication: Theoretical Population Biology
publication_status: published
publisher: Academic Press
publist_id: '3336'
quality_controlled: 0
status: public
title: The rate at which asexual populations cross fitness valleys
type: journal_article
volume: 75
year: '2009'
...
---
_id: '3309'
abstract:
- lang: eng
  text: |2-


    Mastitis, a worldwide endemic disease of dairy cows, is an important cause of decreased efficiency in milk production. Early medical treatment can reduce the nonreversible losses in milk production caused by this infection. Various diagnostic tests for mastitis are available, including a test measuring the electrical conductivity of milk (MEC test), the industry standard of somatic cell counting (SCC test), a bacteriological test, and a recently developed test measuring mammary associated amyloid A (MAA test). None of these tests is considered a gold standard, however. The aim of the present study was to determine which of these tests provides the best results, and at what cost, to improve the efficiency of milk production. For this study, 25 cows were tested at all four quarters of the udder with each of the aforementioned mastitis diagnostic tests. Based on the data, the disease prevalence as well as the sensitivity and the specificity of the four tests were estimated with a Bayesian approach by extending the Hui and Walter model with two independent tests and two populations to a model with four partially dependent tests and one population. This model was further combined with a receiver operating characteristics analysis to estimate the overall test accuracy.
author:
- first_name: Caroline
  full_name: Caroline Uhler
  id: 49ADD78E-F248-11E8-B48F-1D18A9856A87
  last_name: Uhler
  orcid: 0000-0002-7008-0216
citation:
  ama: 'Uhler C. Mastitis in dairy production: Estimation of sensitivity, specificity
    and disease prevalence in the absence of a gold standard. <i>Journal of Agricultural
    Biological and Environmental Statistics</i>. 2009;14(1):79-98. doi:<a href="https://doi.org/10.1198/jabes.2009.0005">10.1198/jabes.2009.0005</a>'
  apa: 'Uhler, C. (2009). Mastitis in dairy production: Estimation of sensitivity,
    specificity and disease prevalence in the absence of a gold standard. <i>Journal
    of Agricultural Biological and Environmental Statistics</i>. Springer. <a href="https://doi.org/10.1198/jabes.2009.0005">https://doi.org/10.1198/jabes.2009.0005</a>'
  chicago: 'Uhler, Caroline. “Mastitis in Dairy Production: Estimation of Sensitivity,
    Specificity and Disease Prevalence in the Absence of a Gold Standard.” <i>Journal
    of Agricultural Biological and Environmental Statistics</i>. Springer, 2009. <a
    href="https://doi.org/10.1198/jabes.2009.0005">https://doi.org/10.1198/jabes.2009.0005</a>.'
  ieee: 'C. Uhler, “Mastitis in dairy production: Estimation of sensitivity, specificity
    and disease prevalence in the absence of a gold standard,” <i>Journal of Agricultural
    Biological and Environmental Statistics</i>, vol. 14, no. 1. Springer, pp. 79–98,
    2009.'
  ista: 'Uhler C. 2009. Mastitis in dairy production: Estimation of sensitivity, specificity
    and disease prevalence in the absence of a gold standard. Journal of Agricultural
    Biological and Environmental Statistics. 14(1), 79–98.'
  mla: 'Uhler, Caroline. “Mastitis in Dairy Production: Estimation of Sensitivity,
    Specificity and Disease Prevalence in the Absence of a Gold Standard.” <i>Journal
    of Agricultural Biological and Environmental Statistics</i>, vol. 14, no. 1, Springer,
    2009, pp. 79–98, doi:<a href="https://doi.org/10.1198/jabes.2009.0005">10.1198/jabes.2009.0005</a>.'
  short: C. Uhler, Journal of Agricultural Biological and Environmental Statistics
    14 (2009) 79–98.
date_created: 2018-12-11T12:02:35Z
date_published: 2009-03-01T00:00:00Z
date_updated: 2021-01-12T07:42:33Z
day: '01'
doi: 10.1198/jabes.2009.0005
extern: 1
intvolume: '        14'
issue: '1'
month: '03'
page: 79 - 98
publication: Journal of Agricultural Biological and Environmental Statistics
publication_status: published
publisher: Springer
publist_id: '3331'
quality_controlled: 0
status: public
title: 'Mastitis in dairy production: Estimation of sensitivity, specificity and disease
  prevalence in the absence of a gold standard'
type: journal_article
volume: 14
year: '2009'
...
---
_id: '110'
abstract:
- lang: eng
  text: In order to better understand magnetic reconnection and particle acceleration
    in solar flares, we compare the RHESSI hard X-ray (HXR) footpoint motions of three
    flares with a detailed study of the corresponding topology given by a Magnetic
    Charge Topology model. We analyze the relationship between the footpoint motions
    and topological spine lines and find that the examined footpoint sources move
    along spine lines. We present a three-dimensional topological model in which this
    movement can be understood. As reconnection proceeds, flux is transferred between
    the reconnecting domains, causing the separator to move. The movement of the separator\'s
    chromospheric ends, identified with the HXR footpoints, is along those spine lines
    on which the separator ends.
acknowledgement: This work was supported by RHESSI funds from the University of California
  at Berkeley through a contract, SA1868-26308PG, with Montana State University. Funding
  for our Research Experience for Undergraduates (REU) students was provided by NSF
  grant ATM-0243923.
author:
- first_name: Angela
  full_name: Des Jardins, Angela
  last_name: Des Jardins
- first_name: Richard
  full_name: Canfield, Richard
  last_name: Canfield
- first_name: Dana
  full_name: Longcope, Dana
  last_name: Longcope
- first_name: Crystal
  full_name: Fordyce, Crystal
  last_name: Fordyce
- first_name: Scott R
  full_name: Waitukaitis, Scott R
  id: 3A1FFC16-F248-11E8-B48F-1D18A9856A87
  last_name: Waitukaitis
  orcid: 0000-0002-2299-3176
citation:
  ama: 'Des Jardins A, Canfield R, Longcope D, Fordyce C, Waitukaitis SR. Reconnection
    in three dimensions: The role of spines in three eruptive flares. <i>The Astrophysical
    Journal</i>. 2009;693(2):1628-1636. doi:<a href="https://doi.org/10.1088/0004-637X/693/2/1628">10.1088/0004-637X/693/2/1628</a>'
  apa: 'Des Jardins, A., Canfield, R., Longcope, D., Fordyce, C., &#38; Waitukaitis,
    S. R. (2009). Reconnection in three dimensions: The role of spines in three eruptive
    flares. <i>The Astrophysical Journal</i>. IOP Publishing Ltd. <a href="https://doi.org/10.1088/0004-637X/693/2/1628">https://doi.org/10.1088/0004-637X/693/2/1628</a>'
  chicago: 'Des Jardins, Angela, Richard Canfield, Dana Longcope, Crystal Fordyce,
    and Scott R Waitukaitis. “Reconnection in Three Dimensions: The Role of Spines
    in Three Eruptive Flares.” <i>The Astrophysical Journal</i>. IOP Publishing Ltd.,
    2009. <a href="https://doi.org/10.1088/0004-637X/693/2/1628">https://doi.org/10.1088/0004-637X/693/2/1628</a>.'
  ieee: 'A. Des Jardins, R. Canfield, D. Longcope, C. Fordyce, and S. R. Waitukaitis,
    “Reconnection in three dimensions: The role of spines in three eruptive flares,”
    <i>The Astrophysical Journal</i>, vol. 693, no. 2. IOP Publishing Ltd., pp. 1628–1636,
    2009.'
  ista: 'Des Jardins A, Canfield R, Longcope D, Fordyce C, Waitukaitis SR. 2009. Reconnection
    in three dimensions: The role of spines in three eruptive flares. The Astrophysical
    Journal. 693(2), 1628–1636.'
  mla: 'Des Jardins, Angela, et al. “Reconnection in Three Dimensions: The Role of
    Spines in Three Eruptive Flares.” <i>The Astrophysical Journal</i>, vol. 693,
    no. 2, IOP Publishing Ltd., 2009, pp. 1628–36, doi:<a href="https://doi.org/10.1088/0004-637X/693/2/1628">10.1088/0004-637X/693/2/1628</a>.'
  short: A. Des Jardins, R. Canfield, D. Longcope, C. Fordyce, S.R. Waitukaitis, The
    Astrophysical Journal 693 (2009) 1628–1636.
date_created: 2018-12-11T11:44:41Z
date_published: 2009-03-10T00:00:00Z
date_updated: 2021-01-12T06:48:16Z
day: '10'
doi: 10.1088/0004-637X/693/2/1628
extern: '1'
intvolume: '       693'
issue: '2'
language:
- iso: eng
month: '03'
oa_version: None
page: 1628 - 1636
publication: The Astrophysical Journal
publication_status: published
publisher: IOP Publishing Ltd.
publist_id: '7944'
quality_controlled: '1'
status: public
title: 'Reconnection in three dimensions: The role of spines in three eruptive flares'
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 693
year: '2009'
...
---
_id: '111'
abstract:
- lang: eng
  text: Thin streams of liquid commonly break up into characteristic droplet patterns
    owing to the surface-tension-driven PlateauRayleigh instability 1-3. Very similar
    patterns are observed when initially uniform streams of dry granular material
    break up into clusters of grains4-6, even though flows of macroscopic particles
    are considered to lack surface tension7,8. Recent studies on freely falling granular
    streams tracked fluctuations in the stream profile9, but the clustering mechanism
    remained unresolved because the full evolution of the instability could not be
    observed. Here we demonstrate that the cluster formation is driven by minute,
    nanoNewton cohesive forces that arise from a combination of van der Waals interactions
    and capillary bridges between nanometre-scale surface asperities. Our experiments
    involve high-speed video imaging of the granular stream in the co-moving frame,
    control over the properties of the grain surfaces and the use of atomic force
    microscopy to measure grain-grain interactions. The cohesive forces that we measure
    correspond to an equivalent surface tension five orders of magnitude below that,
    of ordinary liquids. We find that, the shapes of these weakly cohesive, non-thermal
    clusters of macroscopic particles closely resemble droplets resulting from thermally
    induced rupture of liquid nanojets 10-12.
acknowledgement: This work was supported by NSF through its MRSEC programme and the
  Inter-American Materials Collaboration Chicago-Chile, and by the Keck Initiative
  for Ultrafast Imaging at the University of Chicago.
author:
- first_name: John
  full_name: Royer, John
  last_name: Royer
- first_name: Daniel
  full_name: Evans, Daniel
  last_name: Evans
- first_name: Loreto
  full_name: Oyarte, Loreto
  last_name: Oyarte
- first_name: Qiti
  full_name: Guo, Qiti
  last_name: Guo
- first_name: Eliot
  full_name: Kapit, Eliot
  last_name: Kapit
- first_name: Matthias
  full_name: Möbius, Matthias
  last_name: Möbius
- first_name: Scott R
  full_name: Waitukaitis, Scott R
  id: 3A1FFC16-F248-11E8-B48F-1D18A9856A87
  last_name: Waitukaitis
  orcid: 0000-0002-2299-3176
- first_name: Heinrich
  full_name: Jaeger, Heinrich
  last_name: Jaeger
citation:
  ama: Royer J, Evans D, Oyarte L, et al. High-speed tracking of rupture and clustering
    in freely falling granular streams. <i>Nature</i>. 2009;459(7250):1110-1113. doi:<a
    href="https://doi.org/10.1038/nature08115">10.1038/nature08115</a>
  apa: Royer, J., Evans, D., Oyarte, L., Guo, Q., Kapit, E., Möbius, M., … Jaeger,
    H. (2009). High-speed tracking of rupture and clustering in freely falling granular
    streams. <i>Nature</i>. Nature Publishing Group. <a href="https://doi.org/10.1038/nature08115">https://doi.org/10.1038/nature08115</a>
  chicago: Royer, John, Daniel Evans, Loreto Oyarte, Qiti Guo, Eliot Kapit, Matthias
    Möbius, Scott R Waitukaitis, and Heinrich Jaeger. “High-Speed Tracking of Rupture
    and Clustering in Freely Falling Granular Streams.” <i>Nature</i>. Nature Publishing
    Group, 2009. <a href="https://doi.org/10.1038/nature08115">https://doi.org/10.1038/nature08115</a>.
  ieee: J. Royer <i>et al.</i>, “High-speed tracking of rupture and clustering in
    freely falling granular streams,” <i>Nature</i>, vol. 459, no. 7250. Nature Publishing
    Group, pp. 1110–1113, 2009.
  ista: Royer J, Evans D, Oyarte L, Guo Q, Kapit E, Möbius M, Waitukaitis SR, Jaeger
    H. 2009. High-speed tracking of rupture and clustering in freely falling granular
    streams. Nature. 459(7250), 1110–1113.
  mla: Royer, John, et al. “High-Speed Tracking of Rupture and Clustering in Freely
    Falling Granular Streams.” <i>Nature</i>, vol. 459, no. 7250, Nature Publishing
    Group, 2009, pp. 1110–13, doi:<a href="https://doi.org/10.1038/nature08115">10.1038/nature08115</a>.
  short: J. Royer, D. Evans, L. Oyarte, Q. Guo, E. Kapit, M. Möbius, S.R. Waitukaitis,
    H. Jaeger, Nature 459 (2009) 1110–1113.
date_created: 2018-12-11T11:44:41Z
date_published: 2009-06-25T00:00:00Z
date_updated: 2021-01-12T06:48:21Z
day: '25'
doi: 10.1038/nature08115
extern: '1'
intvolume: '       459'
issue: '7250'
language:
- iso: eng
month: '06'
oa_version: None
page: 1110 - 1113
publication: Nature
publication_status: published
publisher: Nature Publishing Group
publist_id: '7943'
quality_controlled: '1'
status: public
title: High-speed tracking of rupture and clustering in freely falling granular streams
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 459
year: '2009'
...
---
_id: '11103'
abstract:
- lang: eng
  text: Over the last decade, the nuclear envelope (NE) has emerged as a key component
    in the organization and function of the nuclear genome. As many as 100 different
    proteins are thought to specifically localize to this double membrane that separates
    the cytoplasm and the nucleoplasm of eukaryotic cells. Selective portals through
    the NE are formed at sites where the inner and outer nuclear membranes are fused,
    and the coincident assembly of ∼30 proteins into nuclear pore complexes occurs.
    These nuclear pore complexes are essential for the control of nucleocytoplasmic
    exchange. Many of the NE and nuclear pore proteins are thought to play crucial
    roles in gene regulation and thus are increasingly linked to human diseases.
article_processing_charge: No
article_type: review
author:
- first_name: Martin W
  full_name: HETZER, Martin W
  id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
  last_name: HETZER
  orcid: 0000-0002-2111-992X
- first_name: Susan R.
  full_name: Wente, Susan R.
  last_name: Wente
citation:
  ama: 'Hetzer M, Wente SR. Border control at the nucleus: Biogenesis and organization
    of the nuclear membrane and pore complexes. <i>Developmental Cell</i>. 2009;17(5):606-616.
    doi:<a href="https://doi.org/10.1016/j.devcel.2009.10.007">10.1016/j.devcel.2009.10.007</a>'
  apa: 'Hetzer, M., &#38; Wente, S. R. (2009). Border control at the nucleus: Biogenesis
    and organization of the nuclear membrane and pore complexes. <i>Developmental
    Cell</i>. Elsevier. <a href="https://doi.org/10.1016/j.devcel.2009.10.007">https://doi.org/10.1016/j.devcel.2009.10.007</a>'
  chicago: 'Hetzer, Martin, and Susan R. Wente. “Border Control at the Nucleus: Biogenesis
    and Organization of the Nuclear Membrane and Pore Complexes.” <i>Developmental
    Cell</i>. Elsevier, 2009. <a href="https://doi.org/10.1016/j.devcel.2009.10.007">https://doi.org/10.1016/j.devcel.2009.10.007</a>.'
  ieee: 'M. Hetzer and S. R. Wente, “Border control at the nucleus: Biogenesis and
    organization of the nuclear membrane and pore complexes,” <i>Developmental Cell</i>,
    vol. 17, no. 5. Elsevier, pp. 606–616, 2009.'
  ista: 'Hetzer M, Wente SR. 2009. Border control at the nucleus: Biogenesis and organization
    of the nuclear membrane and pore complexes. Developmental Cell. 17(5), 606–616.'
  mla: 'Hetzer, Martin, and Susan R. Wente. “Border Control at the Nucleus: Biogenesis
    and Organization of the Nuclear Membrane and Pore Complexes.” <i>Developmental
    Cell</i>, vol. 17, no. 5, Elsevier, 2009, pp. 606–16, doi:<a href="https://doi.org/10.1016/j.devcel.2009.10.007">10.1016/j.devcel.2009.10.007</a>.'
  short: M. Hetzer, S.R. Wente, Developmental Cell 17 (2009) 606–616.
date_created: 2022-04-07T07:53:45Z
date_published: 2009-11-17T00:00:00Z
date_updated: 2022-07-18T08:55:01Z
day: '17'
doi: 10.1016/j.devcel.2009.10.007
extern: '1'
external_id:
  pmid:
  - '19922866'
intvolume: '        17'
issue: '5'
keyword:
- Developmental Biology
- Cell Biology
- General Biochemistry
- Genetics and Molecular Biology
- Molecular Biology
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.devcel.2009.10.007
month: '11'
oa: 1
oa_version: Published Version
page: 606-616
pmid: 1
publication: Developmental Cell
publication_identifier:
  issn:
  - 1534-5807
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Border control at the nucleus: Biogenesis and organization of the nuclear
  membrane and pore complexes'
type: journal_article
user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd
volume: 17
year: '2009'
...
---
_id: '11105'
abstract:
- lang: eng
  text: Nuclear-pore complexes (NPCs) are large protein channels that span the nuclear
    envelope (NE), which is a double membrane that encloses the nuclear genome of
    eukaryotes. Each of the typically 2,000–4,000 pores in the NE of vertebrate cells
    is composed of multiple copies of 30 different proteins known as nucleoporins.
    The evolutionarily conserved NPC proteins have the well-characterized function
    of mediating the transport of molecules between the nucleoplasm and the cytoplasm.
    Mutations in nucleoporins are often linked to specific developmental defects and
    disease, and the resulting phenotypes are usually interpreted as the consequences
    of perturbed nuclear transport activity. However, recent evidence suggests that
    NPCs have additional functions in chromatin organization and gene regulation,
    some of which might be independent of nuclear transport. Here, we review the transport-dependent
    and transport-independent roles of NPCs in the regulation of nuclear function
    and gene expression.
article_processing_charge: No
article_type: original
author:
- first_name: Maya
  full_name: Capelson, Maya
  last_name: Capelson
- first_name: Martin W
  full_name: HETZER, Martin W
  id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
  last_name: HETZER
  orcid: 0000-0002-2111-992X
citation:
  ama: Capelson M, Hetzer M. The role of nuclear pores in gene regulation, development
    and disease. <i>EMBO reports</i>. 2009;10(7):697-705. doi:<a href="https://doi.org/10.1038/embor.2009.147">10.1038/embor.2009.147</a>
  apa: Capelson, M., &#38; Hetzer, M. (2009). The role of nuclear pores in gene regulation,
    development and disease. <i>EMBO Reports</i>. EMBO. <a href="https://doi.org/10.1038/embor.2009.147">https://doi.org/10.1038/embor.2009.147</a>
  chicago: Capelson, Maya, and Martin Hetzer. “The Role of Nuclear Pores in Gene Regulation,
    Development and Disease.” <i>EMBO Reports</i>. EMBO, 2009. <a href="https://doi.org/10.1038/embor.2009.147">https://doi.org/10.1038/embor.2009.147</a>.
  ieee: M. Capelson and M. Hetzer, “The role of nuclear pores in gene regulation,
    development and disease,” <i>EMBO reports</i>, vol. 10, no. 7. EMBO, pp. 697–705,
    2009.
  ista: Capelson M, Hetzer M. 2009. The role of nuclear pores in gene regulation,
    development and disease. EMBO reports. 10(7), 697–705.
  mla: Capelson, Maya, and Martin Hetzer. “The Role of Nuclear Pores in Gene Regulation,
    Development and Disease.” <i>EMBO Reports</i>, vol. 10, no. 7, EMBO, 2009, pp.
    697–705, doi:<a href="https://doi.org/10.1038/embor.2009.147">10.1038/embor.2009.147</a>.
  short: M. Capelson, M. Hetzer, EMBO Reports 10 (2009) 697–705.
date_created: 2022-04-07T07:54:06Z
date_published: 2009-07-01T00:00:00Z
date_updated: 2022-07-18T08:42:44Z
day: '01'
doi: 10.1038/embor.2009.147
extern: '1'
external_id:
  pmid:
  - '19543230'
intvolume: '        10'
issue: '7'
keyword:
- Genetics
- Molecular Biology
- Biochemistry
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1038/embor.2009.147
month: '07'
oa: 1
oa_version: Published Version
page: 697-705
pmid: 1
publication: EMBO reports
publication_identifier:
  eissn:
  - 1469-3178
  issn:
  - 1469-221X
publication_status: published
publisher: EMBO
quality_controlled: '1'
related_material:
  link:
  - relation: erratum
    url: https://doi.org/10.1038/embor.2009.176
scopus_import: '1'
status: public
title: The role of nuclear pores in gene regulation, development and disease
type: journal_article
user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd
volume: 10
year: '2009'
...
---
_id: '11106'
abstract:
- lang: eng
  text: Formation of the nuclear envelope (NE) around segregated chromosomes occurs
    by the reshaping of the endoplasmic reticulum (ER), a reservoir for disassembled
    nuclear membrane components during mitosis. In this study, we show that inner
    nuclear membrane proteins such as lamin B receptor (LBR), MAN1, Lap2β, and the
    trans-membrane nucleoporins Ndc1 and POM121 drive the spreading of ER membranes
    into the emerging NE via their capacity to bind chromatin in a collaborative manner.
    Despite their redundant functions, decreasing the levels of any of these trans-membrane
    proteins by RNAi-mediated knockdown delayed NE formation, whereas increasing the
    levels of any of them had the opposite effect. Furthermore, acceleration of NE
    formation interferes with chromosome separation during mitosis, indicating that
    the time frame over which chromatin becomes membrane enclosed is physiologically
    relevant and regulated. These data suggest that functionally distinct classes
    of chromatin-interacting membrane proteins, which are present at nonsaturating
    levels, collaborate to rapidly reestablish the nuclear compartment at the end
    of mitosis.
article_processing_charge: No
article_type: original
author:
- first_name: Daniel J.
  full_name: Anderson, Daniel J.
  last_name: Anderson
- first_name: Jesse D.
  full_name: Vargas, Jesse D.
  last_name: Vargas
- first_name: Joshua P.
  full_name: Hsiao, Joshua P.
  last_name: Hsiao
- first_name: Martin W
  full_name: HETZER, Martin W
  id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
  last_name: HETZER
  orcid: 0000-0002-2111-992X
citation:
  ama: Anderson DJ, Vargas JD, Hsiao JP, Hetzer M. Recruitment of functionally distinct
    membrane proteins to chromatin mediates nuclear envelope formation in vivo. <i>Journal
    of Cell Biology</i>. 2009;186(2):183-191. doi:<a href="https://doi.org/10.1083/jcb.200901106">10.1083/jcb.200901106</a>
  apa: Anderson, D. J., Vargas, J. D., Hsiao, J. P., &#38; Hetzer, M. (2009). Recruitment
    of functionally distinct membrane proteins to chromatin mediates nuclear envelope
    formation in vivo. <i>Journal of Cell Biology</i>. Rockefeller University Press.
    <a href="https://doi.org/10.1083/jcb.200901106">https://doi.org/10.1083/jcb.200901106</a>
  chicago: Anderson, Daniel J., Jesse D. Vargas, Joshua P. Hsiao, and Martin Hetzer.
    “Recruitment of Functionally Distinct Membrane Proteins to Chromatin Mediates
    Nuclear Envelope Formation in Vivo.” <i>Journal of Cell Biology</i>. Rockefeller
    University Press, 2009. <a href="https://doi.org/10.1083/jcb.200901106">https://doi.org/10.1083/jcb.200901106</a>.
  ieee: D. J. Anderson, J. D. Vargas, J. P. Hsiao, and M. Hetzer, “Recruitment of
    functionally distinct membrane proteins to chromatin mediates nuclear envelope
    formation in vivo,” <i>Journal of Cell Biology</i>, vol. 186, no. 2. Rockefeller
    University Press, pp. 183–191, 2009.
  ista: Anderson DJ, Vargas JD, Hsiao JP, Hetzer M. 2009. Recruitment of functionally
    distinct membrane proteins to chromatin mediates nuclear envelope formation in
    vivo. Journal of Cell Biology. 186(2), 183–191.
  mla: Anderson, Daniel J., et al. “Recruitment of Functionally Distinct Membrane
    Proteins to Chromatin Mediates Nuclear Envelope Formation in Vivo.” <i>Journal
    of Cell Biology</i>, vol. 186, no. 2, Rockefeller University Press, 2009, pp.
    183–91, doi:<a href="https://doi.org/10.1083/jcb.200901106">10.1083/jcb.200901106</a>.
  short: D.J. Anderson, J.D. Vargas, J.P. Hsiao, M. Hetzer, Journal of Cell Biology
    186 (2009) 183–191.
date_created: 2022-04-07T07:54:18Z
date_published: 2009-07-20T00:00:00Z
date_updated: 2022-07-18T08:58:35Z
day: '20'
doi: 10.1083/jcb.200901106
extern: '1'
external_id:
  pmid:
  - '19620630'
intvolume: '       186'
issue: '2'
keyword:
- Cell Biology
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1083/jcb.200901106
month: '07'
oa: 1
oa_version: Published Version
page: 183-191
pmid: 1
publication: Journal of Cell Biology
publication_identifier:
  eissn:
  - 1540-8140
  issn:
  - 0021-9525
publication_status: published
publisher: Rockefeller University Press
quality_controlled: '1'
related_material:
  link:
  - relation: erratum
    url: https://doi.org/10.1083/jcb.20090110620090903c
scopus_import: '1'
status: public
title: Recruitment of functionally distinct membrane proteins to chromatin mediates
  nuclear envelope formation in vivo
type: journal_article
user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd
volume: 186
year: '2009'
...
---
_id: '11107'
abstract:
- lang: eng
  text: Nucleocytoplasmic transport occurs exclusively through nuclear pore complexes
    (NPCs) embedded in pores formed by inner and outer nuclear membrane fusion. The
    mechanism for de novo pore and NPC biogenesis remains unclear. Reticulons (RTNs)
    and Yop1/DP1 are conserved membrane protein families required to form and maintain
    the tubular endoplasmic reticulum (ER) and the postmitotic nuclear envelope. In
    this study, we report that members of the RTN and Yop1/DP1 families are required
    for nuclear pore formation. Analysis of Saccharomyces cerevisiae prp20-G282S and
    nup133Δ NPC assembly mutants revealed perturbations in Rtn1–green fluorescent
    protein (GFP) and Yop1-GFP ER distribution and colocalization to NPC clusters.
    Combined deletion of RTN1 and YOP1 resulted in NPC clustering, nuclear import
    defects, and synthetic lethality with the additional absence of Pom34, Pom152,
    and Nup84 subcomplex members. We tested for a direct role in NPC biogenesis using
    Xenopus laevis in vitro assays and found that anti-Rtn4a antibodies specifically
    inhibited de novo nuclear pore formation. We hypothesize that these ER membrane–bending
    proteins mediate early NPC assembly steps.
article_processing_charge: No
article_type: original
author:
- first_name: T. Renee
  full_name: Dawson, T. Renee
  last_name: Dawson
- first_name: Michelle D.
  full_name: Lazarus, Michelle D.
  last_name: Lazarus
- first_name: Martin W
  full_name: HETZER, Martin W
  id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
  last_name: HETZER
  orcid: 0000-0002-2111-992X
- first_name: Susan R.
  full_name: Wente, Susan R.
  last_name: Wente
citation:
  ama: Dawson TR, Lazarus MD, Hetzer M, Wente SR. ER membrane–bending proteins are
    necessary for de novo nuclear pore formation. <i>Journal of Cell Biology</i>.
    2009;184(5):659-675. doi:<a href="https://doi.org/10.1083/jcb.200806174">10.1083/jcb.200806174</a>
  apa: Dawson, T. R., Lazarus, M. D., Hetzer, M., &#38; Wente, S. R. (2009). ER membrane–bending
    proteins are necessary for de novo nuclear pore formation. <i>Journal of Cell
    Biology</i>. Rockefeller University Press. <a href="https://doi.org/10.1083/jcb.200806174">https://doi.org/10.1083/jcb.200806174</a>
  chicago: Dawson, T. Renee, Michelle D. Lazarus, Martin Hetzer, and Susan R. Wente.
    “ER Membrane–Bending Proteins Are Necessary for de Novo Nuclear Pore Formation.”
    <i>Journal of Cell Biology</i>. Rockefeller University Press, 2009. <a href="https://doi.org/10.1083/jcb.200806174">https://doi.org/10.1083/jcb.200806174</a>.
  ieee: T. R. Dawson, M. D. Lazarus, M. Hetzer, and S. R. Wente, “ER membrane–bending
    proteins are necessary for de novo nuclear pore formation,” <i>Journal of Cell
    Biology</i>, vol. 184, no. 5. Rockefeller University Press, pp. 659–675, 2009.
  ista: Dawson TR, Lazarus MD, Hetzer M, Wente SR. 2009. ER membrane–bending proteins
    are necessary for de novo nuclear pore formation. Journal of Cell Biology. 184(5),
    659–675.
  mla: Dawson, T. Renee, et al. “ER Membrane–Bending Proteins Are Necessary for de
    Novo Nuclear Pore Formation.” <i>Journal of Cell Biology</i>, vol. 184, no. 5,
    Rockefeller University Press, 2009, pp. 659–75, doi:<a href="https://doi.org/10.1083/jcb.200806174">10.1083/jcb.200806174</a>.
  short: T.R. Dawson, M.D. Lazarus, M. Hetzer, S.R. Wente, Journal of Cell Biology
    184 (2009) 659–675.
date_created: 2022-04-07T07:54:44Z
date_published: 2009-03-09T00:00:00Z
date_updated: 2022-07-18T08:55:05Z
day: '09'
doi: 10.1083/jcb.200806174
extern: '1'
external_id:
  pmid:
  - '19273614'
intvolume: '       184'
issue: '5'
keyword:
- Cell Biology
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1083/jcb.200806174
month: '03'
oa: 1
oa_version: Published Version
page: 659-675
pmid: 1
publication: Journal of Cell Biology
publication_identifier:
  eissn:
  - 1540-8140
  issn:
  - 0021-9525
publication_status: published
publisher: Rockefeller University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: ER membrane–bending proteins are necessary for de novo nuclear pore formation
type: journal_article
user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd
volume: 184
year: '2009'
...
---
_id: '11108'
abstract:
- lang: eng
  text: In dividing cells, nuclear pore complexes (NPCs) disassemble during mitosis
    and reassemble into the newly forming nuclei. However, the fate of nuclear pores
    in postmitotic cells is unknown. Here, we show that NPCs, unlike other nuclear
    structures, do not turn over in differentiated cells. While a subset of NPC components,
    like Nup153 and Nup50, are continuously exchanged, scaffold nucleoporins, like
    the Nup107/160 complex, are extremely long-lived and remain incorporated in the
    nuclear membrane during the entire cellular life span. Besides the lack of nucleoporin
    expression and NPC turnover, we discovered an age-related deterioration of NPCs,
    leading to an increase in nuclear permeability and the leaking of cytoplasmic
    proteins into the nucleus. Our finding that nuclear “leakiness” is dramatically
    accelerated during aging and that a subset of nucleoporins is oxidatively damaged
    in old cells suggests that the accumulation of damage at the NPC might be a crucial
    aging event.
article_processing_charge: No
article_type: original
author:
- first_name: Maximiliano A.
  full_name: D'Angelo, Maximiliano A.
  last_name: D'Angelo
- first_name: Marcela
  full_name: Raices, Marcela
  last_name: Raices
- first_name: Siler H.
  full_name: Panowski, Siler H.
  last_name: Panowski
- first_name: Martin W
  full_name: HETZER, Martin W
  id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
  last_name: HETZER
  orcid: 0000-0002-2111-992X
citation:
  ama: D’Angelo MA, Raices M, Panowski SH, Hetzer M. Age-dependent deterioration of
    nuclear pore complexes causes a loss of nuclear integrity in postmitotic cells.
    <i>Cell</i>. 2009;136(2):284-295. doi:<a href="https://doi.org/10.1016/j.cell.2008.11.037">10.1016/j.cell.2008.11.037</a>
  apa: D’Angelo, M. A., Raices, M., Panowski, S. H., &#38; Hetzer, M. (2009). Age-dependent
    deterioration of nuclear pore complexes causes a loss of nuclear integrity in
    postmitotic cells. <i>Cell</i>. Elsevier. <a href="https://doi.org/10.1016/j.cell.2008.11.037">https://doi.org/10.1016/j.cell.2008.11.037</a>
  chicago: D’Angelo, Maximiliano A., Marcela Raices, Siler H. Panowski, and Martin
    Hetzer. “Age-Dependent Deterioration of Nuclear Pore Complexes Causes a Loss of
    Nuclear Integrity in Postmitotic Cells.” <i>Cell</i>. Elsevier, 2009. <a href="https://doi.org/10.1016/j.cell.2008.11.037">https://doi.org/10.1016/j.cell.2008.11.037</a>.
  ieee: M. A. D’Angelo, M. Raices, S. H. Panowski, and M. Hetzer, “Age-dependent deterioration
    of nuclear pore complexes causes a loss of nuclear integrity in postmitotic cells,”
    <i>Cell</i>, vol. 136, no. 2. Elsevier, pp. 284–295, 2009.
  ista: D’Angelo MA, Raices M, Panowski SH, Hetzer M. 2009. Age-dependent deterioration
    of nuclear pore complexes causes a loss of nuclear integrity in postmitotic cells.
    Cell. 136(2), 284–295.
  mla: D’Angelo, Maximiliano A., et al. “Age-Dependent Deterioration of Nuclear Pore
    Complexes Causes a Loss of Nuclear Integrity in Postmitotic Cells.” <i>Cell</i>,
    vol. 136, no. 2, Elsevier, 2009, pp. 284–95, doi:<a href="https://doi.org/10.1016/j.cell.2008.11.037">10.1016/j.cell.2008.11.037</a>.
  short: M.A. D’Angelo, M. Raices, S.H. Panowski, M. Hetzer, Cell 136 (2009) 284–295.
date_created: 2022-04-07T07:54:52Z
date_published: 2009-01-23T00:00:00Z
date_updated: 2022-07-18T08:55:29Z
day: '23'
doi: 10.1016/j.cell.2008.11.037
extern: '1'
external_id:
  pmid:
  - '19167330'
intvolume: '       136'
issue: '2'
keyword:
- General Biochemistry
- Genetics and Molecular Biology
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.cell.2008.11.037
month: '01'
oa: 1
oa_version: Published Version
page: 284-295
pmid: 1
publication: Cell
publication_identifier:
  issn:
  - 0092-8674
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Age-dependent deterioration of nuclear pore complexes causes a loss of nuclear
  integrity in postmitotic cells
type: journal_article
user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd
volume: 136
year: '2009'
...
---
_id: '11752'
abstract:
- lang: eng
  text: We propose a model which suggests that structural martensitic transitions
    are related to significant changes in the electronic structure, and are effected
    by high-magnetic fields. The magnetic field dependence is considered unusual as
    many influential investigations of martensitic transitions have emphasized that
    the structural transitions are primarily lattice dynamical and are driven by the
    entropy due to the phonons. We provide a theoretical framework which can be used
    to describe the effect of high magnetic field on the transition and lattice dynamics
    in which the field dependence originates from the dielectric constant. The model
    is compared with some recent experimental results.
alternative_title:
- JPCS
article_number: '032062'
article_processing_charge: No
author:
- first_name: Xiaodong
  full_name: Yang, Xiaodong
  last_name: Yang
- first_name: Peter S
  full_name: Riseborough, Peter S
  last_name: Riseborough
- first_name: Kimberly A
  full_name: Modic, Kimberly A
  id: 13C26AC0-EB69-11E9-87C6-5F3BE6697425
  last_name: Modic
  orcid: 0000-0001-9760-3147
- first_name: R A
  full_name: Fisher, R A
  last_name: Fisher
- first_name: C P
  full_name: Oppeil, C P
  last_name: Oppeil
- first_name: T R
  full_name: Finlayson, T R
  last_name: Finlayson
- first_name: J C
  full_name: Cooley, J C
  last_name: Cooley
- first_name: J L
  full_name: Smith, J L
  last_name: Smith
- first_name: P A
  full_name: Goddard, P A
  last_name: Goddard
- first_name: A V
  full_name: Silhanek, A V
  last_name: Silhanek
- first_name: J C
  full_name: Lashley, J C
  last_name: Lashley
citation:
  ama: 'Yang X, Riseborough PS, Modic KA, et al. Influence of magnetic fields on structural
    martensitic transitions. In: <i>Journal of Physics: Conference Series</i>. Vol
    200. IOP Publishing; 2009. doi:<a href="https://doi.org/10.1088/1742-6596/200/3/032062">10.1088/1742-6596/200/3/032062</a>'
  apa: 'Yang, X., Riseborough, P. S., Modic, K. A., Fisher, R. A., Oppeil, C. P.,
    Finlayson, T. R., … Lashley, J. C. (2009). Influence of magnetic fields on structural
    martensitic transitions. In <i>Journal of Physics: Conference Series</i> (Vol.
    200). Karlsruhe, Germany: IOP Publishing. <a href="https://doi.org/10.1088/1742-6596/200/3/032062">https://doi.org/10.1088/1742-6596/200/3/032062</a>'
  chicago: 'Yang, Xiaodong, Peter S Riseborough, Kimberly A Modic, R A Fisher, C P
    Oppeil, T R Finlayson, J C Cooley, et al. “Influence of Magnetic Fields on Structural
    Martensitic Transitions.” In <i>Journal of Physics: Conference Series</i>, Vol.
    200. IOP Publishing, 2009. <a href="https://doi.org/10.1088/1742-6596/200/3/032062">https://doi.org/10.1088/1742-6596/200/3/032062</a>.'
  ieee: 'X. Yang <i>et al.</i>, “Influence of magnetic fields on structural martensitic
    transitions,” in <i>Journal of Physics: Conference Series</i>, Karlsruhe, Germany,
    2009, vol. 200, no. 3.'
  ista: 'Yang X, Riseborough PS, Modic KA, Fisher RA, Oppeil CP, Finlayson TR, Cooley
    JC, Smith JL, Goddard PA, Silhanek AV, Lashley JC. 2009. Influence of magnetic
    fields on structural martensitic transitions. Journal of Physics: Conference Series.
    ICM: International Conference on Magnetism, JPCS, vol. 200, 032062.'
  mla: 'Yang, Xiaodong, et al. “Influence of Magnetic Fields on Structural Martensitic
    Transitions.” <i>Journal of Physics: Conference Series</i>, vol. 200, no. 3, 032062,
    IOP Publishing, 2009, doi:<a href="https://doi.org/10.1088/1742-6596/200/3/032062">10.1088/1742-6596/200/3/032062</a>.'
  short: 'X. Yang, P.S. Riseborough, K.A. Modic, R.A. Fisher, C.P. Oppeil, T.R. Finlayson,
    J.C. Cooley, J.L. Smith, P.A. Goddard, A.V. Silhanek, J.C. Lashley, in:, Journal
    of Physics: Conference Series, IOP Publishing, 2009.'
conference:
  end_date: 2009-07-31
  location: Karlsruhe, Germany
  name: 'ICM: International Conference on Magnetism'
  start_date: 2009-07-26
date_created: 2022-08-08T08:43:04Z
date_published: 2009-07-01T00:00:00Z
date_updated: 2023-02-23T12:58:33Z
day: '01'
doi: 10.1088/1742-6596/200/3/032062
extern: '1'
intvolume: '       200'
issue: '3'
language:
- iso: eng
month: '07'
oa_version: None
publication: 'Journal of Physics: Conference Series'
publication_identifier:
  eissn:
  - 1742-6596
  issn:
  - 1742-6588
publication_status: published
publisher: IOP Publishing
quality_controlled: '1'
related_material:
  record:
  - id: '7080'
    relation: later_version
    status: public
scopus_import: '1'
status: public
title: Influence of magnetic fields on structural martensitic transitions
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 200
year: '2009'
...
---
_id: '8026'
abstract:
- lang: eng
  text: Recent theoretical work has provided a basic understanding of signal propagation
    in networks of spiking neurons, but mechanisms for gating and controlling these
    signals have not been investigated previously. Here we introduce an idea for the
    gating of multiple signals in cortical networks that combines principles of signal
    propagation with aspects of balanced networks. Specifically, we studied networks
    in which incoming excitatory signals are normally cancelled by locally evoked
    inhibition, leaving the targeted layer unresponsive. Transmission can be gated
    'on' by modulating excitatory and inhibitory gains to upset this detailed balance.
    We illustrate gating through detailed balance in large networks of integrate-and-fire
    neurons. We show successful gating of multiple signals and study failure modes
    that produce effects reminiscent of clinically observed pathologies. Provided
    that the individual signals are detectable, detailed balance has a large capacity
    for gating multiple signals.
article_processing_charge: No
article_type: original
author:
- first_name: Tim P
  full_name: Vogels, Tim P
  id: CB6FF8D2-008F-11EA-8E08-2637E6697425
  last_name: Vogels
  orcid: 0000-0003-3295-6181
- first_name: L F
  full_name: Abbott, L F
  last_name: Abbott
citation:
  ama: Vogels TP, Abbott LF. Gating multiple signals through detailed balance of excitation
    and inhibition in spiking networks. <i>Nature Neuroscience</i>. 2009;12(4):483-491.
    doi:<a href="https://doi.org/10.1038/nn.2276">10.1038/nn.2276</a>
  apa: Vogels, T. P., &#38; Abbott, L. F. (2009). Gating multiple signals through
    detailed balance of excitation and inhibition in spiking networks. <i>Nature Neuroscience</i>.
    Springer Nature. <a href="https://doi.org/10.1038/nn.2276">https://doi.org/10.1038/nn.2276</a>
  chicago: Vogels, Tim P, and L F Abbott. “Gating Multiple Signals through Detailed
    Balance of Excitation and Inhibition in Spiking Networks.” <i>Nature Neuroscience</i>.
    Springer Nature, 2009. <a href="https://doi.org/10.1038/nn.2276">https://doi.org/10.1038/nn.2276</a>.
  ieee: T. P. Vogels and L. F. Abbott, “Gating multiple signals through detailed balance
    of excitation and inhibition in spiking networks,” <i>Nature Neuroscience</i>,
    vol. 12, no. 4. Springer Nature, pp. 483–491, 2009.
  ista: Vogels TP, Abbott LF. 2009. Gating multiple signals through detailed balance
    of excitation and inhibition in spiking networks. Nature Neuroscience. 12(4),
    483–491.
  mla: Vogels, Tim P., and L. F. Abbott. “Gating Multiple Signals through Detailed
    Balance of Excitation and Inhibition in Spiking Networks.” <i>Nature Neuroscience</i>,
    vol. 12, no. 4, Springer Nature, 2009, pp. 483–91, doi:<a href="https://doi.org/10.1038/nn.2276">10.1038/nn.2276</a>.
  short: T.P. Vogels, L.F. Abbott, Nature Neuroscience 12 (2009) 483–491.
date_created: 2020-06-25T13:10:55Z
date_published: 2009-04-01T00:00:00Z
date_updated: 2021-01-12T08:16:36Z
day: '01'
doi: 10.1038/nn.2276
extern: '1'
external_id:
  pmid:
  - '19305402'
intvolume: '        12'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693069/
month: '04'
oa: 1
oa_version: Submitted Version
page: 483-491
pmid: 1
publication: Nature Neuroscience
publication_identifier:
  issn:
  - 1097-6256
  - 1546-1726
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Gating multiple signals through detailed balance of excitation and inhibition
  in spiking networks
type: journal_article
user_id: D865714E-FA4E-11E9-B85B-F5C5E5697425
volume: 12
year: '2009'
...
---
_id: '8474'
abstract:
- lang: eng
  text: Hydrogen bonds are ubiquitous interactions in proteins, and are important
    for their folding and functionality. Scalar coupling constants across hydrogen
    bonds in the protein backbone, some as small as 0.5 Hz, can be directly measured
    in the solid state by NMR spectroscopy (see figure). The nuclei on both sides
    of the hydrogen bond can be identified and the size of the coupling constant can
    be measured accurately.
article_processing_charge: No
article_type: original
author:
- first_name: Paul
  full_name: Schanda, Paul
  id: 7B541462-FAF6-11E9-A490-E8DFE5697425
  last_name: Schanda
  orcid: 0000-0002-9350-7606
- first_name: Matthias
  full_name: Huber, Matthias
  last_name: Huber
- first_name: RenÃ©
  full_name: Verel, RenÃ©
  last_name: Verel
- first_name: Matthias
  full_name: Ernst, Matthias
  last_name: Ernst
- first_name: "Beatâ\x80\NH."
  full_name: "Meier, Beatâ\x80\NH."
  last_name: Meier
citation:
  ama: Schanda P, Huber M, Verel R, Ernst M, Meier B. Direct detection of 3hJN’ hydrogen-bond
    scalar couplings in proteins by solid-state NMR spectroscopy. <i>Angewandte Chemie
    International Edition</i>. 2009;48(49):9322-9325. doi:<a href="https://doi.org/10.1002/anie.200904411">10.1002/anie.200904411</a>
  apa: Schanda, P., Huber, M., Verel, R., Ernst, M., &#38; Meier, B. (2009). Direct
    detection of 3hJN’ hydrogen-bond scalar couplings in proteins by solid-state NMR
    spectroscopy. <i>Angewandte Chemie International Edition</i>. Wiley. <a href="https://doi.org/10.1002/anie.200904411">https://doi.org/10.1002/anie.200904411</a>
  chicago: "Schanda, Paul, Matthias Huber, RenÃ© Verel, Matthias Ernst, and Beatâ\x80\NH.
    Meier. “Direct Detection of 3hJN’ Hydrogen-Bond Scalar Couplings in Proteins by
    Solid-State NMR Spectroscopy.” <i>Angewandte Chemie International Edition</i>.
    Wiley, 2009. <a href=\"https://doi.org/10.1002/anie.200904411\">https://doi.org/10.1002/anie.200904411</a>."
  ieee: P. Schanda, M. Huber, R. Verel, M. Ernst, and B. Meier, “Direct detection
    of 3hJN’ hydrogen-bond scalar couplings in proteins by solid-state NMR spectroscopy,”
    <i>Angewandte Chemie International Edition</i>, vol. 48, no. 49. Wiley, pp. 9322–9325,
    2009.
  ista: Schanda P, Huber M, Verel R, Ernst M, Meier B. 2009. Direct detection of 3hJN’
    hydrogen-bond scalar couplings in proteins by solid-state NMR spectroscopy. Angewandte
    Chemie International Edition. 48(49), 9322–9325.
  mla: Schanda, Paul, et al. “Direct Detection of 3hJN’ Hydrogen-Bond Scalar Couplings
    in Proteins by Solid-State NMR Spectroscopy.” <i>Angewandte Chemie International
    Edition</i>, vol. 48, no. 49, Wiley, 2009, pp. 9322–25, doi:<a href="https://doi.org/10.1002/anie.200904411">10.1002/anie.200904411</a>.
  short: P. Schanda, M. Huber, R. Verel, M. Ernst, B. Meier, Angewandte Chemie International
    Edition 48 (2009) 9322–9325.
date_created: 2020-09-18T10:11:33Z
date_published: 2009-11-17T00:00:00Z
date_updated: 2021-01-12T08:19:31Z
day: '17'
doi: 10.1002/anie.200904411
extern: '1'
intvolume: '        48'
issue: '49'
keyword:
- General Chemistry
- Catalysis
language:
- iso: eng
month: '11'
oa_version: None
page: 9322-9325
publication: Angewandte Chemie International Edition
publication_identifier:
  issn:
  - 1433-7851
  - 1521-3773
publication_status: published
publisher: Wiley
quality_controlled: '1'
status: public
title: Direct detection of 3hJN' hydrogen-bond scalar couplings in proteins by solid-state
  NMR spectroscopy
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 48
year: '2009'
...
---
_id: '8475'
article_processing_charge: No
article_type: original
author:
- first_name: Paul
  full_name: Schanda, Paul
  id: 7B541462-FAF6-11E9-A490-E8DFE5697425
  last_name: Schanda
  orcid: 0000-0002-9350-7606
citation:
  ama: 'Schanda P. Fast-pulsing longitudinal relaxation optimized techniques: Enriching
    the toolbox of fast biomolecular NMR spectroscopy. <i>Progress in Nuclear Magnetic
    Resonance Spectroscopy</i>. 2009;55(3):238-265. doi:<a href="https://doi.org/10.1016/j.pnmrs.2009.05.002">10.1016/j.pnmrs.2009.05.002</a>'
  apa: 'Schanda, P. (2009). Fast-pulsing longitudinal relaxation optimized techniques:
    Enriching the toolbox of fast biomolecular NMR spectroscopy. <i>Progress in Nuclear
    Magnetic Resonance Spectroscopy</i>. Elsevier. <a href="https://doi.org/10.1016/j.pnmrs.2009.05.002">https://doi.org/10.1016/j.pnmrs.2009.05.002</a>'
  chicago: 'Schanda, Paul. “Fast-Pulsing Longitudinal Relaxation Optimized Techniques:
    Enriching the Toolbox of Fast Biomolecular NMR Spectroscopy.” <i>Progress in Nuclear
    Magnetic Resonance Spectroscopy</i>. Elsevier, 2009. <a href="https://doi.org/10.1016/j.pnmrs.2009.05.002">https://doi.org/10.1016/j.pnmrs.2009.05.002</a>.'
  ieee: 'P. Schanda, “Fast-pulsing longitudinal relaxation optimized techniques: Enriching
    the toolbox of fast biomolecular NMR spectroscopy,” <i>Progress in Nuclear Magnetic
    Resonance Spectroscopy</i>, vol. 55, no. 3. Elsevier, pp. 238–265, 2009.'
  ista: 'Schanda P. 2009. Fast-pulsing longitudinal relaxation optimized techniques:
    Enriching the toolbox of fast biomolecular NMR spectroscopy. Progress in Nuclear
    Magnetic Resonance Spectroscopy. 55(3), 238–265.'
  mla: 'Schanda, Paul. “Fast-Pulsing Longitudinal Relaxation Optimized Techniques:
    Enriching the Toolbox of Fast Biomolecular NMR Spectroscopy.” <i>Progress in Nuclear
    Magnetic Resonance Spectroscopy</i>, vol. 55, no. 3, Elsevier, 2009, pp. 238–65,
    doi:<a href="https://doi.org/10.1016/j.pnmrs.2009.05.002">10.1016/j.pnmrs.2009.05.002</a>.'
  short: P. Schanda, Progress in Nuclear Magnetic Resonance Spectroscopy 55 (2009)
    238–265.
date_created: 2020-09-18T10:11:42Z
date_published: 2009-10-01T00:00:00Z
date_updated: 2021-01-12T08:19:32Z
day: '01'
doi: 10.1016/j.pnmrs.2009.05.002
extern: '1'
intvolume: '        55'
issue: '3'
language:
- iso: eng
month: '10'
oa_version: None
page: 238-265
publication: Progress in Nuclear Magnetic Resonance Spectroscopy
publication_identifier:
  issn:
  - 0079-6565
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: 'Fast-pulsing longitudinal relaxation optimized techniques: Enriching the toolbox
  of fast biomolecular NMR spectroscopy'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 55
year: '2009'
...
---
_id: '8476'
abstract:
- lang: eng
  text: Atomic-resolution information on the structure and dynamics of nucleic acids
    is essential for a better understanding of the mechanistic basis of many cellular
    processes. NMR spectroscopy is a powerful method for studying the structure and
    dynamics of nucleic acids; however, solution NMR studies are currently limited
    to relatively small nucleic acids at high concentrations. Thus, technological
    and methodological improvements that increase the experimental sensitivity and
    spectral resolution of NMR spectroscopy are required for studies of larger nucleic
    acids or protein−nucleic acid complexes. Here we introduce a series of imino-proton-detected
    NMR experiments that yield an over 2-fold increase in sensitivity compared to
    conventional pulse schemes. These methods can be applied to the detection of base
    pair interactions, RNA−ligand titration experiments, measurement of residual dipolar
    15N−1H couplings, and direct measurements of conformational transitions. These
    NMR experiments employ longitudinal spin relaxation enhancement techniques that
    have proven useful in protein NMR spectroscopy. The performance of these new experiments
    is demonstrated for a 10 kDa TAR-TAR*GA RNA kissing complex and a 26 kDa tRNA.
article_processing_charge: No
article_type: original
author:
- first_name: Jonathan
  full_name: Farjon, Jonathan
  last_name: Farjon
- first_name: Jérôme
  full_name: Boisbouvier, Jérôme
  last_name: Boisbouvier
- first_name: Paul
  full_name: Schanda, Paul
  id: 7B541462-FAF6-11E9-A490-E8DFE5697425
  last_name: Schanda
  orcid: 0000-0002-9350-7606
- first_name: Arthur
  full_name: Pardi, Arthur
  last_name: Pardi
- first_name: Jean-Pierre
  full_name: Simorre, Jean-Pierre
  last_name: Simorre
- first_name: Bernhard
  full_name: Brutscher, Bernhard
  last_name: Brutscher
citation:
  ama: Farjon J, Boisbouvier J, Schanda P, Pardi A, Simorre J-P, Brutscher B. Longitudinal-relaxation-enhanced
    NMR experiments for the study of nucleic acids in solution. <i>Journal of the
    American Chemical Society</i>. 2009;131(24):8571-8577. doi:<a href="https://doi.org/10.1021/ja901633y">10.1021/ja901633y</a>
  apa: Farjon, J., Boisbouvier, J., Schanda, P., Pardi, A., Simorre, J.-P., &#38;
    Brutscher, B. (2009). Longitudinal-relaxation-enhanced NMR experiments for the
    study of nucleic acids in solution. <i>Journal of the American Chemical Society</i>.
    American Chemical Society. <a href="https://doi.org/10.1021/ja901633y">https://doi.org/10.1021/ja901633y</a>
  chicago: Farjon, Jonathan, Jérôme Boisbouvier, Paul Schanda, Arthur Pardi, Jean-Pierre
    Simorre, and Bernhard Brutscher. “Longitudinal-Relaxation-Enhanced NMR Experiments
    for the Study of Nucleic Acids in Solution.” <i>Journal of the American Chemical
    Society</i>. American Chemical Society, 2009. <a href="https://doi.org/10.1021/ja901633y">https://doi.org/10.1021/ja901633y</a>.
  ieee: J. Farjon, J. Boisbouvier, P. Schanda, A. Pardi, J.-P. Simorre, and B. Brutscher,
    “Longitudinal-relaxation-enhanced NMR experiments for the study of nucleic acids
    in solution,” <i>Journal of the American Chemical Society</i>, vol. 131, no. 24.
    American Chemical Society, pp. 8571–8577, 2009.
  ista: Farjon J, Boisbouvier J, Schanda P, Pardi A, Simorre J-P, Brutscher B. 2009.
    Longitudinal-relaxation-enhanced NMR experiments for the study of nucleic acids
    in solution. Journal of the American Chemical Society. 131(24), 8571–8577.
  mla: Farjon, Jonathan, et al. “Longitudinal-Relaxation-Enhanced NMR Experiments
    for the Study of Nucleic Acids in Solution.” <i>Journal of the American Chemical
    Society</i>, vol. 131, no. 24, American Chemical Society, 2009, pp. 8571–77, doi:<a
    href="https://doi.org/10.1021/ja901633y">10.1021/ja901633y</a>.
  short: J. Farjon, J. Boisbouvier, P. Schanda, A. Pardi, J.-P. Simorre, B. Brutscher,
    Journal of the American Chemical Society 131 (2009) 8571–8577.
date_created: 2020-09-18T10:11:49Z
date_published: 2009-06-01T00:00:00Z
date_updated: 2021-01-12T08:19:32Z
day: '01'
doi: 10.1021/ja901633y
extern: '1'
intvolume: '       131'
issue: '24'
language:
- iso: eng
month: '06'
oa_version: None
page: 8571-8577
publication: Journal of the American Chemical Society
publication_identifier:
  issn:
  - 0002-7863
  - 1520-5126
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
status: public
title: Longitudinal-relaxation-enhanced NMR experiments for the study of nucleic acids
  in solution
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 131
year: '2009'
...
