---
_id: '752'
abstract:
- lang: eng
text: Set agreement is a fundamental problem in distributed computing in which processes
collectively choose a small subset of values from a larger set of proposals. The
impossibility of fault-tolerant set agreement in asynchronous networks is one
of the seminal results in distributed computing. The complexity of set agreement
in synchronous networks has also been a significant research challenge. Real systems,
however, are neither purely synchronous nor purely asynchronous. Rather, they
tend to alternate between periods of synchrony and periods of asynchrony. In this
paper, we analyze the complexity of set agreement in a "partially synchronous"
setting, presenting the first (asymptotically) tight bound on the complexity of
set agreement in such systems. We introduce a novel technique for simulating,
in fault-prone asynchronous shared memory, executions of an asynchronous and failure-prone
messagepassing system in which some fragments appear synchronous to some processes.
We use this technique to derive a lower bound on the round complexity of set agreement
in a partially synchronous system by a reduction from asynchronous wait-free set
agreement. We also present an asymptotically matching algorithm that relies on
a distributed asynchrony detection mechanism to decide as soon as possible during
periods of synchrony. By relating environments with differing degrees of synchrony,
our simulation technique is of independent interest. In particular, it allows
us to obtain a new lower bound on the complexity of early deciding k-set agreement
complementary to that of [12], and to re-derive the combinatorial topology lower
bound of [13] in an algorithmic way.
acknowledgement: Corentin Travers was supposrted in part by a Sam & Cecilia Neaman
Fellowship
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Dan-Adrian
full_name: Alistarh, Dan-Adrian
id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
last_name: Alistarh
orcid: 0000-0003-3650-940X
- first_name: Seth
full_name: Gilbert, Seth
last_name: Gilbert
- first_name: Rachid
full_name: Guerraoui, Rachid
last_name: Guerraoui
- first_name: Corentin
full_name: Travers, Corentin
last_name: Travers
citation:
ama: 'Alistarh D-A, Gilbert S, Guerraoui R, Travers C. Of choices, failures and
asynchrony: the many faces of set agreement. In: Vol 5878 LNCS. Springer; 2009:943-953.
doi:10.1007/978-3-642-10631-6_95'
apa: 'Alistarh, D.-A., Gilbert, S., Guerraoui, R., & Travers, C. (2009). Of
choices, failures and asynchrony: the many faces of set agreement (Vol. 5878 LNCS,
pp. 943–953). Presented at the ISAAC: International Symposium on Algorithms and
Computation, Springer. https://doi.org/10.1007/978-3-642-10631-6_95'
chicago: 'Alistarh, Dan-Adrian, Seth Gilbert, Rachid Guerraoui, and Corentin Travers.
“Of Choices, Failures and Asynchrony: The Many Faces of Set Agreement,” 5878 LNCS:943–53.
Springer, 2009. https://doi.org/10.1007/978-3-642-10631-6_95.'
ieee: 'D.-A. Alistarh, S. Gilbert, R. Guerraoui, and C. Travers, “Of choices, failures
and asynchrony: the many faces of set agreement,” presented at the ISAAC: International
Symposium on Algorithms and Computation, 2009, vol. 5878 LNCS, pp. 943–953.'
ista: 'Alistarh D-A, Gilbert S, Guerraoui R, Travers C. 2009. Of choices, failures
and asynchrony: the many faces of set agreement. ISAAC: International Symposium
on Algorithms and Computation, LNCS, vol. 5878 LNCS, 943–953.'
mla: 'Alistarh, Dan-Adrian, et al. Of Choices, Failures and Asynchrony: The Many
Faces of Set Agreement. Vol. 5878 LNCS, Springer, 2009, pp. 943–53, doi:10.1007/978-3-642-10631-6_95.'
short: D.-A. Alistarh, S. Gilbert, R. Guerraoui, C. Travers, in:, Springer, 2009,
pp. 943–953.
conference:
name: 'ISAAC: International Symposium on Algorithms and Computation'
date_created: 2018-12-11T11:48:19Z
date_published: 2009-01-01T00:00:00Z
date_updated: 2023-02-23T13:10:05Z
day: '01'
doi: 10.1007/978-3-642-10631-6_95
extern: '1'
language:
- iso: eng
month: '01'
oa_version: None
page: 943 - 953
publication_status: published
publisher: Springer
publist_id: '6903'
status: public
title: 'Of choices, failures and asynchrony: the many faces of set agreement'
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 5878 LNCS
year: '2009'
...
---
_id: '7751'
abstract:
- lang: eng
text: "This work demonstrates that environmental conditions experienced by individuals
can shape their development and affect the stability of genetic associations.
The implication of this observation is that the environmental response may influence
the evolution of traits in the wild. Here, we examined how the genetic architecture
of a suite of sexually dimorphic traits changed as a function of environmental
conditions in an unmanaged population of Soay sheep (Ovis aries) on the island
of Hirta, St. Kilda, northwest Scotland. We examined the stability of phenotypic,
genetic, and environmental (residual) covariance in males during the first year
of life between horn length, body weight, and parasite load in environments of
different quality. We then examined the same covariance structures across environments
within and between the adult sexes. We found significant genotype-by-environment
interactions for lamb male body weight and parasite load, leading to a change
in the genetic correlation among environments. Horn length was genetically correlated
with body weight in males but not females and the genetic correlation among traits
within and between the sexes was dependent upon the environmental conditions experienced
during adulthood. Genetic correlations were smaller in more favorable environmental
conditions, suggesting that in good environments, loci are expressed that have
sex-specific effects. The reduction in genetic correlation between the sexes may
allow independent evolutionary trajectories for each sex. This study demonstrates
that the genetic architecture of traits is not stable under temporally varying
environments and highlights the fact that evolutionary processes may depend largely
upon ecological conditions.\r\nENVIRONMENTAL heterogeneity has long been recognized
as an important factor influencing the evolution of fitness-related traits in
the wild (Roff 2002). The evolution of a trait depends upon the selection upon
it, underlying genetic variation, and to a large degree the genetic relationships
with other traits (Lynch and Walsh 1998). There is evidence that selection can
vary considerably from year to year (Price et al. 1984; Robinson et al. 2008)
and genetic variability in quantitative traits can change in response to environmental
conditions (Hoffmann and Merilä 1999; Charmantier and Garant 2005). However, we
know surprisingly little about the influence of environmental conditions on genetic
correlations between traits in wild populations. Laboratory evidence suggests
that the environment may influence genetic relationships between traits (Sgrò
and Hoffmann 2004), but estimates obtained in a controlled or in an arbitrary
range of conditions show a lack of concordance with those obtained in wild habitats
(Conner et al. 2003). As a result, laboratory and environment-specific estimates
of genetic correlations can make predictions for a trait's evolution, but these
are valid only for the environment in which they were measured. Therefore, at
present, it is difficult to generalize about the evolution of a trait that is
expressed in populations that experience variable environmental conditions (Steppan
et al. 2002).\r\nThe influence of changing environmental conditions on the G matrix
(the matrix of additive genetic variance and covariances corresponding to a set
of traits) has been the focus of theoretical quantitative genetic studies (e.g.,
Jones et al. 2003). There is evidence of genotype-by-environment interaction for
many traits expressed in wild populations (Charmantier and Garant 2005) and thus
we may also expect that associations between traits may depend upon the environmental
conditions encountered by an individual. Genetic correlations among traits may
arise from pleiotropy, where a given locus affects more than one trait (Cheverud
1988; Lynch and Walsh 1998), which may limit the potential for those traits to
evolve independently. There has recently been much interest in assessing genetic
correlations between the sexes (Rice and Chippindale 2001; Foerster et al. 2007;
Poissant et al. 2008), but all of these predictions have also been made in average
environmental conditions. For sexually dimorphic traits, expectations of between-sex
genetic correlations are unclear (Lande 1980; Badyaev 2002). We might expect that
the genetic determination of a trait and the patterns of genetic covariance between
traits may differ both within and between the sexes, producing the differences
in trait growth that are commonly observed (Lande 1980; Badyaev 2002; Roff 2002),
but so far evidence suggests that genetic expression in both sexes is influenced
by the same developmental pathway (Roff 2002; Jensen et al. 2003; Parker and Garant
2005). However, to our knowledge, no study has yet determined whether genetic
correlations, both within and between the sexes, vary across gradients of the
environmental conditions encountered by individuals in the wild (Garant et al.
2008).\r\nThis study aims to assess the stability of phenotypic, genetic, and
environmental (residual) associations between traits, within and between the sexes,
across a range of environmental conditions experienced by a wild population. We
focus on the traits of horn length, body weight, and parasite load in a feral
population of Soay sheep (Ovis aries) from the island of Hirta, St. Kilda, United
Kingdom. Weather conditions, population density, and consequently resource availability
fluctuate from year to year, providing substantial differences between individuals
in the environments they experience and thus their survival rates (Clutton-Brock
and Pemberton 2004). These varying conditions, combined with a large pedigree
and extensive repeated morphological measures, provide an excellent opportunity
to assess the potential effects of environmental heterogeneity on genetic architecture
of traits. Previous studies on this population have shown additive genetic variance
for many morphological traits (Milner et al. 2000; Coltman et al. 2001; Wilson
et al. 2005), genetic correlations between traits (Coltman et al. 2001), and genotype-by-environment
interactions for birth weight (Wilson et al. 2006). Here we apply a random regression
animal model approach to assess the extent to which quantitative genetic parameters
of a range of morphological traits measured during life vary as a function of
environmental conditions. We then extend this methodology to the multivariate
case, testing whether the phenotypic covariance structure, and the underlying
G matrix, depends on the environmental conditions experienced. Since the traits
considered here are known to be sexually dimorphic and there are differences in
trait growth and survival across ages, we look at sex-specific traits in lambs
and then across all ages."
article_processing_charge: No
article_type: original
author:
- first_name: Matthew Richard
full_name: Robinson, Matthew Richard
id: E5D42276-F5DA-11E9-8E24-6303E6697425
last_name: Robinson
orcid: 0000-0001-8982-8813
- first_name: Alastair J.
full_name: Wilson, Alastair J.
last_name: Wilson
- first_name: Jill G.
full_name: Pilkington, Jill G.
last_name: Pilkington
- first_name: Tim H.
full_name: Clutton-Brock, Tim H.
last_name: Clutton-Brock
- first_name: Josephine M.
full_name: Pemberton, Josephine M.
last_name: Pemberton
- first_name: Loeske E. B.
full_name: Kruuk, Loeske E. B.
last_name: Kruuk
citation:
ama: Robinson MR, Wilson AJ, Pilkington JG, Clutton-Brock TH, Pemberton JM, Kruuk
LEB. The impact of environmental heterogeneity on genetic architecture in a wild
population of soay sheep. Genetics. 2009;181(4):1639-1648. doi:10.1534/genetics.108.086801
apa: Robinson, M. R., Wilson, A. J., Pilkington, J. G., Clutton-Brock, T. H., Pemberton,
J. M., & Kruuk, L. E. B. (2009). The impact of environmental heterogeneity
on genetic architecture in a wild population of soay sheep. Genetics. Genetics
Society of America. https://doi.org/10.1534/genetics.108.086801
chicago: Robinson, Matthew Richard, Alastair J. Wilson, Jill G. Pilkington, Tim
H. Clutton-Brock, Josephine M. Pemberton, and Loeske E. B. Kruuk. “The Impact
of Environmental Heterogeneity on Genetic Architecture in a Wild Population of
Soay Sheep.” Genetics. Genetics Society of America, 2009. https://doi.org/10.1534/genetics.108.086801.
ieee: M. R. Robinson, A. J. Wilson, J. G. Pilkington, T. H. Clutton-Brock, J. M.
Pemberton, and L. E. B. Kruuk, “The impact of environmental heterogeneity on genetic
architecture in a wild population of soay sheep,” Genetics, vol. 181, no.
4. Genetics Society of America, pp. 1639–1648, 2009.
ista: Robinson MR, Wilson AJ, Pilkington JG, Clutton-Brock TH, Pemberton JM, Kruuk
LEB. 2009. The impact of environmental heterogeneity on genetic architecture in
a wild population of soay sheep. Genetics. 181(4), 1639–1648.
mla: Robinson, Matthew Richard, et al. “The Impact of Environmental Heterogeneity
on Genetic Architecture in a Wild Population of Soay Sheep.” Genetics,
vol. 181, no. 4, Genetics Society of America, 2009, pp. 1639–48, doi:10.1534/genetics.108.086801.
short: M.R. Robinson, A.J. Wilson, J.G. Pilkington, T.H. Clutton-Brock, J.M. Pemberton,
L.E.B. Kruuk, Genetics 181 (2009) 1639–1648.
date_created: 2020-04-30T11:01:57Z
date_published: 2009-04-01T00:00:00Z
date_updated: 2021-01-12T08:15:17Z
day: '01'
doi: 10.1534/genetics.108.086801
extern: '1'
intvolume: ' 181'
issue: '4'
language:
- iso: eng
month: '04'
oa_version: None
page: 1639-1648
publication: Genetics
publication_identifier:
issn:
- 0016-6731
- 1943-2631
publication_status: published
publisher: Genetics Society of America
quality_controlled: '1'
status: public
title: The impact of environmental heterogeneity on genetic architecture in a wild
population of soay sheep
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 181
year: '2009'
...
---
_id: '8026'
abstract:
- lang: eng
text: Recent theoretical work has provided a basic understanding of signal propagation
in networks of spiking neurons, but mechanisms for gating and controlling these
signals have not been investigated previously. Here we introduce an idea for the
gating of multiple signals in cortical networks that combines principles of signal
propagation with aspects of balanced networks. Specifically, we studied networks
in which incoming excitatory signals are normally cancelled by locally evoked
inhibition, leaving the targeted layer unresponsive. Transmission can be gated
'on' by modulating excitatory and inhibitory gains to upset this detailed balance.
We illustrate gating through detailed balance in large networks of integrate-and-fire
neurons. We show successful gating of multiple signals and study failure modes
that produce effects reminiscent of clinically observed pathologies. Provided
that the individual signals are detectable, detailed balance has a large capacity
for gating multiple signals.
article_processing_charge: No
article_type: original
author:
- first_name: Tim P
full_name: Vogels, Tim P
id: CB6FF8D2-008F-11EA-8E08-2637E6697425
last_name: Vogels
orcid: 0000-0003-3295-6181
- first_name: L F
full_name: Abbott, L F
last_name: Abbott
citation:
ama: Vogels TP, Abbott LF. Gating multiple signals through detailed balance of excitation
and inhibition in spiking networks. Nature Neuroscience. 2009;12(4):483-491.
doi:10.1038/nn.2276
apa: Vogels, T. P., & Abbott, L. F. (2009). Gating multiple signals through
detailed balance of excitation and inhibition in spiking networks. Nature Neuroscience.
Springer Nature. https://doi.org/10.1038/nn.2276
chicago: Vogels, Tim P, and L F Abbott. “Gating Multiple Signals through Detailed
Balance of Excitation and Inhibition in Spiking Networks.” Nature Neuroscience.
Springer Nature, 2009. https://doi.org/10.1038/nn.2276.
ieee: T. P. Vogels and L. F. Abbott, “Gating multiple signals through detailed balance
of excitation and inhibition in spiking networks,” Nature Neuroscience,
vol. 12, no. 4. Springer Nature, pp. 483–491, 2009.
ista: Vogels TP, Abbott LF. 2009. Gating multiple signals through detailed balance
of excitation and inhibition in spiking networks. Nature Neuroscience. 12(4),
483–491.
mla: Vogels, Tim P., and L. F. Abbott. “Gating Multiple Signals through Detailed
Balance of Excitation and Inhibition in Spiking Networks.” Nature Neuroscience,
vol. 12, no. 4, Springer Nature, 2009, pp. 483–91, doi:10.1038/nn.2276.
short: T.P. Vogels, L.F. Abbott, Nature Neuroscience 12 (2009) 483–491.
date_created: 2020-06-25T13:10:55Z
date_published: 2009-04-01T00:00:00Z
date_updated: 2021-01-12T08:16:36Z
day: '01'
doi: 10.1038/nn.2276
extern: '1'
external_id:
pmid:
- '19305402'
intvolume: ' 12'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693069/
month: '04'
oa: 1
oa_version: Submitted Version
page: 483-491
pmid: 1
publication: Nature Neuroscience
publication_identifier:
issn:
- 1097-6256
- 1546-1726
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Gating multiple signals through detailed balance of excitation and inhibition
in spiking networks
type: journal_article
user_id: D865714E-FA4E-11E9-B85B-F5C5E5697425
volume: 12
year: '2009'
...
---
_id: '164'
abstract:
- lang: eng
text: Let g be a cubic polynomial with integer coefficients and n>9 variables,
and assume that the congruence g=0 modulo p^k is soluble for all prime powers
p^k. We show that the equation g=0 has infinitely many integer solutions when
the cubic part of g defines a projective hypersurface with singular locus of dimension
<n-10. The proof is based on the Hardy-Littlewood circle method.
article_processing_charge: No
arxiv: 1
author:
- first_name: Timothy D
full_name: Browning, Timothy D
id: 35827D50-F248-11E8-B48F-1D18A9856A87
last_name: Browning
orcid: 0000-0002-8314-0177
- first_name: Roger
full_name: Heath Brown, Roger
last_name: Heath Brown
citation:
ama: 'Browning TD, Heath Brown R. Integral points on cubic hypersurfaces. In: Analytic
Number Theory: Essays in Honour of Klaus Roth. Cambridge University Press;
2009:75-90.'
apa: 'Browning, T. D., & Heath Brown, R. (2009). Integral points on cubic hypersurfaces.
In Analytic Number Theory: Essays in honour of Klaus Roth (pp. 75–90).
Cambridge University Press.'
chicago: 'Browning, Timothy D, and Roger Heath Brown. “Integral Points on Cubic
Hypersurfaces.” In Analytic Number Theory: Essays in Honour of Klaus Roth,
75–90. Cambridge University Press, 2009.'
ieee: 'T. D. Browning and R. Heath Brown, “Integral points on cubic hypersurfaces,”
in Analytic Number Theory: Essays in honour of Klaus Roth, Cambridge University
Press, 2009, pp. 75–90.'
ista: 'Browning TD, Heath Brown R. 2009.Integral points on cubic hypersurfaces.
In: Analytic Number Theory: Essays in honour of Klaus Roth. , 75–90.'
mla: 'Browning, Timothy D., and Roger Heath Brown. “Integral Points on Cubic Hypersurfaces.”
Analytic Number Theory: Essays in Honour of Klaus Roth, Cambridge University
Press, 2009, pp. 75–90.'
short: 'T.D. Browning, R. Heath Brown, in:, Analytic Number Theory: Essays in Honour
of Klaus Roth, Cambridge University Press, 2009, pp. 75–90.'
date_created: 2018-12-11T11:44:58Z
date_published: 2009-01-31T00:00:00Z
date_updated: 2021-01-12T06:52:11Z
day: '31'
extern: '1'
external_id:
arxiv:
- '0611086'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/math/0611086
month: '01'
oa: 1
oa_version: Preprint
page: 75 - 90
publication: 'Analytic Number Theory: Essays in honour of Klaus Roth'
publication_status: published
publisher: Cambridge University Press
publist_id: '7757'
quality_controlled: '1'
status: public
title: Integral points on cubic hypersurfaces
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2009'
...
---
_id: '165'
abstract:
- lang: eng
text: We survey the state of affairs for the distribution of ℚ-rational points on
non-singular del Pezzo surfaces of low degree, highlighting the recent resolution
of Manin's conjecture for a non-singular del Pezzo surface of degree 4 by la Bretèche
and Browning.
acknowledgement: Proceedings of the 5th China-Japan Seminar
alternative_title:
- Series on number theory and its application
author:
- first_name: Timothy D
full_name: Timothy Browning
id: 35827D50-F248-11E8-B48F-1D18A9856A87
last_name: Browning
orcid: 0000-0002-8314-0177
citation:
ama: 'Browning TD. Resent progress on the quantitative arithmetic of del Pezzo surfaces.
In: Aoki T, Kanemitsu S, Liu J, eds. Vol 6. World Scientific Publishing; 2009:1-18.
doi:https://doi.org/10.1142/9789814289924_0001'
apa: 'Browning, T. D. (2009). Resent progress on the quantitative arithmetic of
del Pezzo surfaces. In T. Aoki, S. Kanemitsu, & J. Liu (Eds.) (Vol. 6, pp.
1–18). Presented at the Number Theory: Dreaming in dreams, World Scientific Publishing.
https://doi.org/10.1142/9789814289924_0001'
chicago: Browning, Timothy D. “Resent Progress on the Quantitative Arithmetic of
Del Pezzo Surfaces.” edited by Takashi Aoki, Shigeru Kanemitsu, and Jianya Liu,
6:1–18. World Scientific Publishing, 2009. https://doi.org/10.1142/9789814289924_0001.
ieee: 'T. D. Browning, “Resent progress on the quantitative arithmetic of del Pezzo
surfaces,” presented at the Number Theory: Dreaming in dreams, 2009, vol. 6, pp.
1–18.'
ista: 'Browning TD. 2009. Resent progress on the quantitative arithmetic of del
Pezzo surfaces. Number Theory: Dreaming in dreams, Series on number theory and
its application, vol. 6, 1–18.'
mla: Browning, Timothy D. Resent Progress on the Quantitative Arithmetic of Del
Pezzo Surfaces. Edited by Takashi Aoki et al., vol. 6, World Scientific Publishing,
2009, pp. 1–18, doi:https://doi.org/10.1142/9789814289924_0001.
short: T.D. Browning, in:, T. Aoki, S. Kanemitsu, J. Liu (Eds.), World Scientific
Publishing, 2009, pp. 1–18.
conference:
name: 'Number Theory: Dreaming in dreams'
date_created: 2018-12-11T11:44:58Z
date_published: 2009-08-24T00:00:00Z
date_updated: 2021-01-12T06:52:15Z
day: '24'
doi: https://doi.org/10.1142/9789814289924_0001
editor:
- first_name: Takashi
full_name: Aoki, Takashi
last_name: Aoki
- first_name: Shigeru
full_name: Kanemitsu, Shigeru
last_name: Kanemitsu
- first_name: Jianya
full_name: Liu, Jianya
last_name: Liu
extern: 1
intvolume: ' 6'
month: '08'
page: 1 - 18
publication_status: published
publisher: World Scientific Publishing
publist_id: '7756'
quality_controlled: 0
status: public
title: Resent progress on the quantitative arithmetic of del Pezzo surfaces
type: conference
volume: 6
year: '2009'
...
---
_id: '168'
abstract:
- lang: eng
text: The arithmetic of ternary diagonal equation is considered for degree d >1,
with the outcome that the set of coefficients for which the equation admits a
non-zero integer solution is shown to have density zero.
alternative_title:
- Contemporary Mathematics
author:
- first_name: Timothy D
full_name: Timothy Browning
id: 35827D50-F248-11E8-B48F-1D18A9856A87
last_name: Browning
orcid: 0000-0002-8314-0177
- first_name: Rainer
full_name: Dietmann, Rainer
last_name: Dietmann
citation:
ama: 'Browning TD, Dietmann R. Solubility of Fermat equations. In: Quadratic
Forms - Algebra, Arithmetic and Geometry. Vol 493. American Mathematical Society;
2009:99-106. doi:http://dx.doi.org/10.1090/conm/493'
apa: Browning, T. D., & Dietmann, R. (2009). Solubility of Fermat equations.
In Quadratic Forms - algebra, arithmetic and geometry (Vol. 493, pp. 99–106).
American Mathematical Society. http://dx.doi.org/10.1090/conm/493
chicago: Browning, Timothy D, and Rainer Dietmann. “Solubility of Fermat Equations.”
In Quadratic Forms - Algebra, Arithmetic and Geometry, 493:99–106. American
Mathematical Society, 2009. http://dx.doi.org/10.1090/conm/493.
ieee: T. D. Browning and R. Dietmann, “Solubility of Fermat equations,” in Quadratic
Forms - algebra, arithmetic and geometry, vol. 493, American Mathematical
Society, 2009, pp. 99–106.
ista: 'Browning TD, Dietmann R. 2009.Solubility of Fermat equations. In: Quadratic
Forms - algebra, arithmetic and geometry. Contemporary Mathematics, vol. 493,
99–106.'
mla: Browning, Timothy D., and Rainer Dietmann. “Solubility of Fermat Equations.”
Quadratic Forms - Algebra, Arithmetic and Geometry, vol. 493, American
Mathematical Society, 2009, pp. 99–106, doi:http://dx.doi.org/10.1090/conm/493.
short: T.D. Browning, R. Dietmann, in:, Quadratic Forms - Algebra, Arithmetic and
Geometry, American Mathematical Society, 2009, pp. 99–106.
date_created: 2018-12-11T11:44:59Z
date_published: 2009-01-01T00:00:00Z
date_updated: 2021-01-12T06:52:29Z
day: '01'
doi: http://dx.doi.org/10.1090/conm/493
extern: 1
intvolume: ' 493'
main_file_link:
- open_access: '0'
url: https://arxiv.org/abs/0805.3354
month: '01'
page: 99 - 106
publication: Quadratic Forms - algebra, arithmetic and geometry
publication_status: published
publisher: American Mathematical Society
publist_id: '7753'
quality_controlled: 0
status: public
title: Solubility of Fermat equations
type: book_chapter
volume: 493
year: '2009'
...
---
_id: '1718'
abstract:
- lang: eng
text: Morphogens act as graded positional cues to control cell fate specification
in many developing tissues. This concept, in which a signaling gradient regulates
differential gene expression in a concentration-dependent manner, has received
considerable experimental support. Nevertheless, several recent studies have challenged
the straightforward model of morphogen activity. In particular, the observation
that pattern formation is a dynamic process has raised questions about the influence
of time on morphogen activity. Here we propose that the spatiotemporal dynamics
of the cellular response to a morphogen gradient depend on a combination of temporal
alterations to the morphogen gradient itself, the dynamics of its signal transduction
and downstream interactions between target genes.
acknowledgement: EK is supported by an EMBO LTF, AK by a FEBS fellowship, and JB by
MRC (UK) and the Wellcome Trust
author:
- first_name: Eva
full_name: Kutějová, Eva
last_name: Kutějová
- first_name: James
full_name: Briscoe, James
last_name: Briscoe
- first_name: Anna
full_name: Anna Kicheva
id: 3959A2A0-F248-11E8-B48F-1D18A9856A87
last_name: Kicheva
orcid: 0000-0003-4509-4998
citation:
ama: Kutějová E, Briscoe J, Kicheva A. Temporal dynamics of patterning by morphogen
gradients. Current Opinion in Genetics & Development. 2009;19(4):315-322.
doi:10.1016/j.gde.2009.05.004
apa: Kutějová, E., Briscoe, J., & Kicheva, A. (2009). Temporal dynamics of patterning
by morphogen gradients. Current Opinion in Genetics & Development.
Elsevier. https://doi.org/10.1016/j.gde.2009.05.004
chicago: Kutějová, Eva, James Briscoe, and Anna Kicheva. “Temporal Dynamics of Patterning
by Morphogen Gradients.” Current Opinion in Genetics & Development.
Elsevier, 2009. https://doi.org/10.1016/j.gde.2009.05.004.
ieee: E. Kutějová, J. Briscoe, and A. Kicheva, “Temporal dynamics of patterning
by morphogen gradients,” Current Opinion in Genetics & Development,
vol. 19, no. 4. Elsevier, pp. 315–322, 2009.
ista: Kutějová E, Briscoe J, Kicheva A. 2009. Temporal dynamics of patterning by
morphogen gradients. Current Opinion in Genetics & Development. 19(4), 315–322.
mla: Kutějová, Eva, et al. “Temporal Dynamics of Patterning by Morphogen Gradients.”
Current Opinion in Genetics & Development, vol. 19, no. 4, Elsevier,
2009, pp. 315–22, doi:10.1016/j.gde.2009.05.004.
short: E. Kutějová, J. Briscoe, A. Kicheva, Current Opinion in Genetics & Development
19 (2009) 315–322.
date_created: 2018-12-11T11:53:38Z
date_published: 2009-08-01T00:00:00Z
date_updated: 2021-01-12T06:52:44Z
day: '01'
doi: 10.1016/j.gde.2009.05.004
extern: 1
intvolume: ' 19'
issue: '4'
month: '08'
page: 315 - 322
publication: Current Opinion in Genetics & Development
publication_status: published
publisher: Elsevier
publist_id: '5410'
quality_controlled: 0
status: public
title: Temporal dynamics of patterning by morphogen gradients
type: journal_article
volume: 19
year: '2009'
...
---
_id: '1720'
abstract:
- lang: eng
text: How morphogen gradients are formed in target tissues is a key question for
understanding the mechanisms of morphological patterning. Here, we review different
mechanisms of morphogen gradient formation from theoretical and experimental points
of view. First, a simple, comprehensive overview of the underlying biophysical
principles of several mechanisms of gradient formation is provided. We then discuss
the advantages and limitations of different experimental approaches to gradient
formation analysis.
author:
- first_name: Ortrud
full_name: Wartlick, Ortrud
last_name: Wartlick
- first_name: Anna
full_name: Anna Kicheva
id: 3959A2A0-F248-11E8-B48F-1D18A9856A87
last_name: Kicheva
orcid: 0000-0003-4509-4998
- first_name: Marcos
full_name: González-Gaitán, Marcos A
last_name: González Gaitán
citation:
ama: Wartlick O, Kicheva A, González Gaitán M. Morphogen gradient formation . Cold
Spring Harbor perspectives in biology. 2009;1(3). doi:10.1101/cshperspect.a001255
apa: Wartlick, O., Kicheva, A., & González Gaitán, M. (2009). Morphogen gradient
formation . Cold Spring Harbor Perspectives in Biology. Cold Spring Harbor
Laboratory Press. https://doi.org/10.1101/cshperspect.a001255
chicago: Wartlick, Ortrud, Anna Kicheva, and Marcos González Gaitán. “Morphogen
Gradient Formation .” Cold Spring Harbor Perspectives in Biology. Cold
Spring Harbor Laboratory Press, 2009. https://doi.org/10.1101/cshperspect.a001255.
ieee: O. Wartlick, A. Kicheva, and M. González Gaitán, “Morphogen gradient formation
,” Cold Spring Harbor perspectives in biology, vol. 1, no. 3. Cold Spring
Harbor Laboratory Press, 2009.
ista: Wartlick O, Kicheva A, González Gaitán M. 2009. Morphogen gradient formation
. Cold Spring Harbor perspectives in biology. 1(3).
mla: Wartlick, Ortrud, et al. “Morphogen Gradient Formation .” Cold Spring Harbor
Perspectives in Biology, vol. 1, no. 3, Cold Spring Harbor Laboratory Press,
2009, doi:10.1101/cshperspect.a001255.
short: O. Wartlick, A. Kicheva, M. González Gaitán, Cold Spring Harbor Perspectives
in Biology 1 (2009).
date_created: 2018-12-11T11:53:39Z
date_published: 2009-09-01T00:00:00Z
date_updated: 2021-01-12T06:52:45Z
day: '01'
doi: 10.1101/cshperspect.a001255
extern: 1
intvolume: ' 1'
issue: '3'
month: '09'
publication: Cold Spring Harbor perspectives in biology
publication_status: published
publisher: Cold Spring Harbor Laboratory Press
publist_id: '5409'
quality_controlled: 0
status: public
title: 'Morphogen gradient formation '
type: journal_article
volume: 1
year: '2009'
...
---
_id: '1766'
abstract:
- lang: eng
text: We demonstrate the time-resolved driving of two-photon blue sideband transitions
between superconducting qubits and a transmission line resonator. As an example
of using these sideband transitions for a two-qubit operation, we implement a
pulse sequence that first entangles one qubit with the resonator and subsequently
distributes the entanglement between two qubits. We show the generation of 75%
fidelity Bell states by this method. The full density matrix of the two-qubit
system is extracted using joint measurement and quantum state tomography and shows
close agreement with numerical simulation.
acknowledgement: This work was supported by ETH Zurich, the Swiss National Science
Foundation, and by the EC via the EuroSQIP project and the Marie-Curie program (P.
J. L.)
author:
- first_name: Peter
full_name: Leek, Peter J
last_name: Leek
- first_name: Stefan
full_name: Filipp, Stefan
last_name: Filipp
- first_name: Patrick
full_name: Maurer, Patrick
last_name: Maurer
- first_name: Matthias
full_name: Baur, Matthias P
last_name: Baur
- first_name: R
full_name: Bianchetti, R
last_name: Bianchetti
- first_name: Johannes M
full_name: Johannes Fink
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
- first_name: M
full_name: Göppl, M
last_name: Göppl
- first_name: L.
full_name: Steffen, L. Kraig
last_name: Steffen
- first_name: Andreas
full_name: Wallraff, Andreas
last_name: Wallraff
citation:
ama: Leek P, Filipp S, Maurer P, et al. Using sideband transitions for two-qubit
operations in superconducting circuits. Physical Review B - Condensed Matter
and Materials Physics. 2009;79(18). doi:10.1103/PhysRevB.79.180511
apa: Leek, P., Filipp, S., Maurer, P., Baur, M., Bianchetti, R., Fink, J. M., …
Wallraff, A. (2009). Using sideband transitions for two-qubit operations in superconducting
circuits. Physical Review B - Condensed Matter and Materials Physics. American
Physical Society. https://doi.org/10.1103/PhysRevB.79.180511
chicago: Leek, Peter, Stefan Filipp, Patrick Maurer, Matthias Baur, R Bianchetti,
Johannes M Fink, M Göppl, L. Steffen, and Andreas Wallraff. “Using Sideband Transitions
for Two-Qubit Operations in Superconducting Circuits.” Physical Review B -
Condensed Matter and Materials Physics. American Physical Society, 2009. https://doi.org/10.1103/PhysRevB.79.180511.
ieee: P. Leek et al., “Using sideband transitions for two-qubit operations
in superconducting circuits,” Physical Review B - Condensed Matter and Materials
Physics, vol. 79, no. 18. American Physical Society, 2009.
ista: Leek P, Filipp S, Maurer P, Baur M, Bianchetti R, Fink JM, Göppl M, Steffen
L, Wallraff A. 2009. Using sideband transitions for two-qubit operations in superconducting
circuits. Physical Review B - Condensed Matter and Materials Physics. 79(18).
mla: Leek, Peter, et al. “Using Sideband Transitions for Two-Qubit Operations in
Superconducting Circuits.” Physical Review B - Condensed Matter and Materials
Physics, vol. 79, no. 18, American Physical Society, 2009, doi:10.1103/PhysRevB.79.180511.
short: P. Leek, S. Filipp, P. Maurer, M. Baur, R. Bianchetti, J.M. Fink, M. Göppl,
L. Steffen, A. Wallraff, Physical Review B - Condensed Matter and Materials Physics
79 (2009).
date_created: 2018-12-11T11:53:54Z
date_published: 2009-05-01T00:00:00Z
date_updated: 2021-01-12T06:53:04Z
day: '01'
doi: 10.1103/PhysRevB.79.180511
extern: 1
intvolume: ' 79'
issue: '18'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/0812.2678
month: '05'
oa: 1
publication: Physical Review B - Condensed Matter and Materials Physics
publication_status: published
publisher: American Physical Society
publist_id: '5354'
quality_controlled: 0
status: public
title: Using sideband transitions for two-qubit operations in superconducting circuits
type: journal_article
volume: 79
year: '2009'
...
---
_id: '1767'
abstract:
- lang: eng
text: We present spectroscopic measurements of the Autler-Townes doublet and the
sidebands of the Mollow triplet in a driven superconducting qubit. The ground
to first excited state transition of the qubit is strongly pumped while the resulting
dressed qubit spectrum is probed with a weak tone. The corresponding transitions
are detected using dispersive readout of the qubit coupled off resonantly to a
microwave transmission line resonator. The observed frequencies of the Autler-Townes
and Mollow spectral lines are in good agreement with a dispersive Jaynes-Cummings
model taking into account higher excited qubit states and dispersive level shifts
due to off-resonant drives.
acknowledgement: This work was supported by the Swiss National Science Foundation
and by ETH Zürich. P. J. L. acknowledges support from the EC via an Intra-European
Marie-Curie Fellowship. A. B. was supported by NSERC, CIFAR, FQRNT, and Alfred P.
Sloan Foundation
author:
- first_name: Matthias
full_name: Baur, Matthias P
last_name: Baur
- first_name: Stefan
full_name: Filipp, Stefan
last_name: Filipp
- first_name: R
full_name: Bianchetti, R
last_name: Bianchetti
- first_name: Johannes M
full_name: Johannes Fink
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
- first_name: M
full_name: Göppl, M
last_name: Göppl
- first_name: L.
full_name: Steffen, L. Kraig
last_name: Steffen
- first_name: Peter
full_name: Leek, Peter J
last_name: Leek
- first_name: Alexandre
full_name: Blais, Alexandre
last_name: Blais
- first_name: Andreas
full_name: Wallraff, Andreas
last_name: Wallraff
citation:
ama: Baur M, Filipp S, Bianchetti R, et al. Measurement of autler-townes and mollow
transitions in a strongly driven superconducting qubit. Physical Review Letters.
2009;102(24). doi:10.1103/PhysRevLett.102.243602
apa: Baur, M., Filipp, S., Bianchetti, R., Fink, J. M., Göppl, M., Steffen, L.,
… Wallraff, A. (2009). Measurement of autler-townes and mollow transitions in
a strongly driven superconducting qubit. Physical Review Letters. American
Physical Society. https://doi.org/10.1103/PhysRevLett.102.243602
chicago: Baur, Matthias, Stefan Filipp, R Bianchetti, Johannes M Fink, M Göppl,
L. Steffen, Peter Leek, Alexandre Blais, and Andreas Wallraff. “Measurement of
Autler-Townes and Mollow Transitions in a Strongly Driven Superconducting Qubit.”
Physical Review Letters. American Physical Society, 2009. https://doi.org/10.1103/PhysRevLett.102.243602.
ieee: M. Baur et al., “Measurement of autler-townes and mollow transitions
in a strongly driven superconducting qubit,” Physical Review Letters, vol.
102, no. 24. American Physical Society, 2009.
ista: Baur M, Filipp S, Bianchetti R, Fink JM, Göppl M, Steffen L, Leek P, Blais
A, Wallraff A. 2009. Measurement of autler-townes and mollow transitions in a
strongly driven superconducting qubit. Physical Review Letters. 102(24).
mla: Baur, Matthias, et al. “Measurement of Autler-Townes and Mollow Transitions
in a Strongly Driven Superconducting Qubit.” Physical Review Letters, vol.
102, no. 24, American Physical Society, 2009, doi:10.1103/PhysRevLett.102.243602.
short: M. Baur, S. Filipp, R. Bianchetti, J.M. Fink, M. Göppl, L. Steffen, P. Leek,
A. Blais, A. Wallraff, Physical Review Letters 102 (2009).
date_created: 2018-12-11T11:53:54Z
date_published: 2009-06-19T00:00:00Z
date_updated: 2021-01-12T06:53:04Z
day: '19'
doi: 10.1103/PhysRevLett.102.243602
extern: 1
intvolume: ' 102'
issue: '24'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/0812.4384
month: '06'
oa: 1
publication: Physical Review Letters
publication_status: published
publisher: American Physical Society
publist_id: '5352'
quality_controlled: 0
status: public
title: Measurement of autler-townes and mollow transitions in a strongly driven superconducting
qubit
type: journal_article
volume: 102
year: '2009'
...
---
_id: '1768'
abstract:
- lang: eng
text: Quantum state tomography is an important tool in quantum information science
for complete characterization of multiqubit states and their correlations. Here
we report a method to perform a joint simultaneous readout of two superconducting
qubits dispersively coupled to the same mode of a microwave transmission line
resonator. The nonlinear dependence of the resonator transmission on the qubit
state dependent cavity frequency allows us to extract the full two-qubit correlations
without the need for single-shot readout of individual qubits. We employ standard
tomographic techniques to reconstruct the density matrix of two-qubit quantum
states.
acknowledgement: This work was supported by Swiss National Science Foundation (SNF)
and ETH Zurich. P. J. L. was supported by the EC with a MC-EIF, J. M. G. by CIFAR,
MRI, MITACS, and NSERC, and A. B. by NSERC and CIFAR
author:
- first_name: Stefan
full_name: Filipp, Stefan
last_name: Filipp
- first_name: Patrick
full_name: Maurer, Patrick
last_name: Maurer
- first_name: Peter
full_name: Leek, Peter J
last_name: Leek
- first_name: Matthias
full_name: Baur, Matthias P
last_name: Baur
- first_name: R
full_name: Bianchetti, R
last_name: Bianchetti
- first_name: Johannes M
full_name: Johannes Fink
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
- first_name: M
full_name: Göppl, M
last_name: Göppl
- first_name: L.
full_name: Steffen, L. Kraig
last_name: Steffen
- first_name: Jay
full_name: Gambetta, Jay M
last_name: Gambetta
- first_name: Alexandre
full_name: Blais, Alexandre
last_name: Blais
- first_name: Andreas
full_name: Wallraff, Andreas
last_name: Wallraff
citation:
ama: Filipp S, Maurer P, Leek P, et al. Two-qubit state tomography using a joint
dispersive readout. Physical Review Letters. 2009;102(20). doi:10.1103/PhysRevLett.102.200402
apa: Filipp, S., Maurer, P., Leek, P., Baur, M., Bianchetti, R., Fink, J. M., …
Wallraff, A. (2009). Two-qubit state tomography using a joint dispersive readout.
Physical Review Letters. American Physical Society. https://doi.org/10.1103/PhysRevLett.102.200402
chicago: Filipp, Stefan, Patrick Maurer, Peter Leek, Matthias Baur, R Bianchetti,
Johannes M Fink, M Göppl, et al. “Two-Qubit State Tomography Using a Joint Dispersive
Readout.” Physical Review Letters. American Physical Society, 2009. https://doi.org/10.1103/PhysRevLett.102.200402.
ieee: S. Filipp et al., “Two-qubit state tomography using a joint dispersive
readout,” Physical Review Letters, vol. 102, no. 20. American Physical
Society, 2009.
ista: Filipp S, Maurer P, Leek P, Baur M, Bianchetti R, Fink JM, Göppl M, Steffen
L, Gambetta J, Blais A, Wallraff A. 2009. Two-qubit state tomography using a joint
dispersive readout. Physical Review Letters. 102(20).
mla: Filipp, Stefan, et al. “Two-Qubit State Tomography Using a Joint Dispersive
Readout.” Physical Review Letters, vol. 102, no. 20, American Physical
Society, 2009, doi:10.1103/PhysRevLett.102.200402.
short: S. Filipp, P. Maurer, P. Leek, M. Baur, R. Bianchetti, J.M. Fink, M. Göppl,
L. Steffen, J. Gambetta, A. Blais, A. Wallraff, Physical Review Letters 102 (2009).
date_created: 2018-12-11T11:53:54Z
date_published: 2009-05-18T00:00:00Z
date_updated: 2021-01-12T06:53:04Z
day: '18'
doi: 10.1103/PhysRevLett.102.200402
extern: 1
intvolume: ' 102'
issue: '20'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/0812.2485
month: '05'
oa: 1
publication: Physical Review Letters
publication_status: published
publisher: American Physical Society
publist_id: '5353'
quality_controlled: 0
status: public
title: Two-qubit state tomography using a joint dispersive readout
type: journal_article
volume: 102
year: '2009'
...
---
_id: '1769'
abstract:
- lang: eng
text: We present an ideal realization of the Tavis-Cummings model in the absence
of atom number and coupling fluctuations by embedding a discrete number of fully
controllable superconducting qubits at fixed positions into a transmission line
resonator. Measuring the vacuum Rabi mode splitting with one, two, and three qubits
strongly coupled to the cavity field, we explore both bright and dark dressed
collective multiqubit states and observe the discrete N scaling of the collective
dipole coupling strength. Our experiments demonstrate a novel approach to explore
collective states, such as the W state, in a fully globally and locally controllable
quantum system. Our scalable approach is interesting for solid-state quantum information
processing and for fundamental multiatom quantum optics experiments with fixed
atom numbers.
acknowledgement: This work was supported by SNF Grant No. 200021-111899 and ETHZ.
P. J. L. was supported by the EU with a MC-EIF. A. B. was supported by NSERC, CIFAR,
and the Alfred P. Sloan Foundation
author:
- first_name: Johannes M
full_name: Johannes Fink
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
- first_name: R
full_name: Bianchetti, R
last_name: Bianchetti
- first_name: Matthias
full_name: Baur, Matthias P
last_name: Baur
- first_name: M
full_name: Göppl, M
last_name: Göppl
- first_name: L.
full_name: Steffen, L. Kraig
last_name: Steffen
- first_name: Stefan
full_name: Filipp, Stefan
last_name: Filipp
- first_name: Peter
full_name: Leek, Peter J
last_name: Leek
- first_name: Alexandre
full_name: Blais, Alexandre
last_name: Blais
- first_name: Andreas
full_name: Wallraff, Andreas
last_name: Wallraff
citation:
ama: Fink JM, Bianchetti R, Baur M, et al. Dressed collective qubit states and the
Tavis-Cummings model in circuit QED. Physical Review Letters. 2009;103(8).
doi:10.1103/PhysRevLett.103.083601
apa: Fink, J. M., Bianchetti, R., Baur, M., Göppl, M., Steffen, L., Filipp, S.,
… Wallraff, A. (2009). Dressed collective qubit states and the Tavis-Cummings
model in circuit QED. Physical Review Letters. American Physical Society.
https://doi.org/10.1103/PhysRevLett.103.083601
chicago: Fink, Johannes M, R Bianchetti, Matthias Baur, M Göppl, L. Steffen, Stefan
Filipp, Peter Leek, Alexandre Blais, and Andreas Wallraff. “Dressed Collective
Qubit States and the Tavis-Cummings Model in Circuit QED.” Physical Review
Letters. American Physical Society, 2009. https://doi.org/10.1103/PhysRevLett.103.083601.
ieee: J. M. Fink et al., “Dressed collective qubit states and the Tavis-Cummings
model in circuit QED,” Physical Review Letters, vol. 103, no. 8. American
Physical Society, 2009.
ista: Fink JM, Bianchetti R, Baur M, Göppl M, Steffen L, Filipp S, Leek P, Blais
A, Wallraff A. 2009. Dressed collective qubit states and the Tavis-Cummings model
in circuit QED. Physical Review Letters. 103(8).
mla: Fink, Johannes M., et al. “Dressed Collective Qubit States and the Tavis-Cummings
Model in Circuit QED.” Physical Review Letters, vol. 103, no. 8, American
Physical Society, 2009, doi:10.1103/PhysRevLett.103.083601.
short: J.M. Fink, R. Bianchetti, M. Baur, M. Göppl, L. Steffen, S. Filipp, P. Leek,
A. Blais, A. Wallraff, Physical Review Letters 103 (2009).
date_created: 2018-12-11T11:53:55Z
date_published: 2009-08-17T00:00:00Z
date_updated: 2021-01-12T06:53:05Z
day: '17'
doi: 10.1103/PhysRevLett.103.083601
extern: 1
intvolume: ' 103'
issue: '8'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/0812.2651
month: '08'
oa: 1
publication: Physical Review Letters
publication_status: published
publisher: American Physical Society
publist_id: '5350'
quality_controlled: 0
status: public
title: Dressed collective qubit states and the Tavis-Cummings model in circuit QED
type: journal_article
volume: 103
year: '2009'
...
---
_id: '1770'
abstract:
- lang: eng
text: The quantum state of a superconducting qubit nonresonantly coupled to a transmission
line resonator can be determined by measuring the quadrature amplitudes of an
electromagnetic field transmitted through the resonator. We present experiments
in which we analyze in detail the dynamics of the transmitted field as a function
of the measurement frequency for both weak continuous and pulsed measurements.
We find excellent agreement between our data and calculations based on a set of
Bloch-type differential equations for the cavity field derived from the dispersive
Jaynes-Cummings Hamiltonian including dissipation. We show that the measured system
response can be used to construct a measurement operator from which the qubit
population can be inferred accurately. Such a measurement operator can be used
in tomographic methods to reconstruct single and multiqubit states in ensemble-averaged
measurements.
acknowledgement: This work was supported by the SNF Project No. 111899 and ETH Zurich.
A.B. was supported by NSERC, CIFAR, and the Alfred P. Sloan Foundation
author:
- first_name: R
full_name: Bianchetti, R
last_name: Bianchetti
- first_name: Stefan
full_name: Filipp, Stefan
last_name: Filipp
- first_name: Matthias
full_name: Baur, Matthias P
last_name: Baur
- first_name: Johannes M
full_name: Johannes Fink
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
- first_name: M
full_name: Göppl, M
last_name: Göppl
- first_name: Peter
full_name: Leek, Peter J
last_name: Leek
- first_name: L.
full_name: Steffen, L. Kraig
last_name: Steffen
- first_name: Alexandre
full_name: Blais, Alexandre
last_name: Blais
- first_name: Andreas
full_name: Wallraff, Andreas
last_name: Wallraff
citation:
ama: Bianchetti R, Filipp S, Baur M, et al. Dynamics of dispersive single-qubit
readout in circuit quantum electrodynamics. Physical Review A - Atomic, Molecular,
and Optical Physics. 2009;80(4). doi:10.1103/PhysRevA.80.043840
apa: Bianchetti, R., Filipp, S., Baur, M., Fink, J. M., Göppl, M., Leek, P., … Wallraff,
A. (2009). Dynamics of dispersive single-qubit readout in circuit quantum electrodynamics.
Physical Review A - Atomic, Molecular, and Optical Physics. American Physical
Society. https://doi.org/10.1103/PhysRevA.80.043840
chicago: Bianchetti, R, Stefan Filipp, Matthias Baur, Johannes M Fink, M Göppl,
Peter Leek, L. Steffen, Alexandre Blais, and Andreas Wallraff. “Dynamics of Dispersive
Single-Qubit Readout in Circuit Quantum Electrodynamics.” Physical Review A
- Atomic, Molecular, and Optical Physics. American Physical Society, 2009.
https://doi.org/10.1103/PhysRevA.80.043840.
ieee: R. Bianchetti et al., “Dynamics of dispersive single-qubit readout
in circuit quantum electrodynamics,” Physical Review A - Atomic, Molecular,
and Optical Physics, vol. 80, no. 4. American Physical Society, 2009.
ista: Bianchetti R, Filipp S, Baur M, Fink JM, Göppl M, Leek P, Steffen L, Blais
A, Wallraff A. 2009. Dynamics of dispersive single-qubit readout in circuit quantum
electrodynamics. Physical Review A - Atomic, Molecular, and Optical Physics. 80(4).
mla: Bianchetti, R., et al. “Dynamics of Dispersive Single-Qubit Readout in Circuit
Quantum Electrodynamics.” Physical Review A - Atomic, Molecular, and Optical
Physics, vol. 80, no. 4, American Physical Society, 2009, doi:10.1103/PhysRevA.80.043840.
short: R. Bianchetti, S. Filipp, M. Baur, J.M. Fink, M. Göppl, P. Leek, L. Steffen,
A. Blais, A. Wallraff, Physical Review A - Atomic, Molecular, and Optical Physics
80 (2009).
date_created: 2018-12-11T11:53:55Z
date_published: 2009-10-30T00:00:00Z
date_updated: 2021-01-12T06:53:05Z
day: '30'
doi: 10.1103/PhysRevA.80.043840
extern: 1
intvolume: ' 80'
issue: '4'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/0907.2549
month: '10'
oa: 1
publication: Physical Review A - Atomic, Molecular, and Optical Physics
publication_status: published
publisher: American Physical Society
publist_id: '5349'
quality_controlled: 0
status: public
title: Dynamics of dispersive single-qubit readout in circuit quantum electrodynamics
type: journal_article
volume: 80
year: '2009'
...
---
_id: '1771'
abstract:
- lang: eng
text: The exceptionally strong coupling realizable between superconducting qubits
and photons stored in an on-chip microwave resonator allows for the detailed study
of matter-light interactions in the realm of circuit quantum electrodynamics (QED).
Here we investigate the resonant interaction between a single transmon-type multilevel
artificial atom and weak thermal and coherent fields. We explore up to three photon
dressed states of the coupled system in a linear response heterodyne transmission
measurement. The results are in good quantitative agreement with a generalized
Jaynes-Cummings model. Our data indicate that the role of thermal fields in resonant
cavity QED can be studied in detail using superconducting circuits.
acknowledgement: Nobel Foundation
author:
- first_name: Johannes M
full_name: Johannes Fink
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
- first_name: Matthias
full_name: Baur, Matthias P
last_name: Baur
- first_name: R
full_name: Bianchetti, R
last_name: Bianchetti
- first_name: Stefan
full_name: Filipp, Stefan
last_name: Filipp
- first_name: M
full_name: Göppl, M
last_name: Göppl
- first_name: Peter
full_name: Leek, Peter J
last_name: Leek
- first_name: L.
full_name: Steffen, L. Kraig
last_name: Steffen
- first_name: Alexandre
full_name: Blais, Alexandre
last_name: Blais
- first_name: Andreas
full_name: Wallraff, Andreas
last_name: Wallraff
citation:
ama: Fink JM, Baur M, Bianchetti R, et al. Thermal excitation of multi-photon dressed
states in circuit quantum electrodynamics. Physica Scripta T. 2009;T137.
doi:10.1088/0031-8949/2009/T137/014013
apa: Fink, J. M., Baur, M., Bianchetti, R., Filipp, S., Göppl, M., Leek, P., … Wallraff,
A. (2009). Thermal excitation of multi-photon dressed states in circuit quantum
electrodynamics. Physica Scripta T. IOP Publishing Ltd. https://doi.org/10.1088/0031-8949/2009/T137/014013
chicago: Fink, Johannes M, Matthias Baur, R Bianchetti, Stefan Filipp, M Göppl,
Peter Leek, L. Steffen, Alexandre Blais, and Andreas Wallraff. “Thermal Excitation
of Multi-Photon Dressed States in Circuit Quantum Electrodynamics.” Physica
Scripta T. IOP Publishing Ltd., 2009. https://doi.org/10.1088/0031-8949/2009/T137/014013.
ieee: J. M. Fink et al., “Thermal excitation of multi-photon dressed states
in circuit quantum electrodynamics,” Physica Scripta T, vol. T137. IOP
Publishing Ltd., 2009.
ista: Fink JM, Baur M, Bianchetti R, Filipp S, Göppl M, Leek P, Steffen L, Blais
A, Wallraff A. 2009. Thermal excitation of multi-photon dressed states in circuit
quantum electrodynamics. Physica Scripta T. T137.
mla: Fink, Johannes M., et al. “Thermal Excitation of Multi-Photon Dressed States
in Circuit Quantum Electrodynamics.” Physica Scripta T, vol. T137, IOP
Publishing Ltd., 2009, doi:10.1088/0031-8949/2009/T137/014013.
short: J.M. Fink, M. Baur, R. Bianchetti, S. Filipp, M. Göppl, P. Leek, L. Steffen,
A. Blais, A. Wallraff, Physica Scripta T T137 (2009).
date_created: 2018-12-11T11:53:55Z
date_published: 2009-01-01T00:00:00Z
date_updated: 2021-01-12T06:53:06Z
day: '01'
doi: 10.1088/0031-8949/2009/T137/014013
extern: 1
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/0911.3797
month: '01'
oa: 1
publication: Physica Scripta T
publication_status: published
publisher: IOP Publishing Ltd.
publist_id: '5348'
quality_controlled: 0
status: public
title: Thermal excitation of multi-photon dressed states in circuit quantum electrodynamics
type: journal_article
volume: T137
year: '2009'
...
---
_id: '1798'
abstract:
- lang: eng
text: The mammalian brain is assembled from thousands of neuronal cell types that
are organized in distinct circuits to perform behaviorally relevant computations.
Transgenic mouse lines with selectively marked cell types would facilitate our
ability to dissect functional components of complex circuits. We carried out a
screen for cell type-specific green fluorescent protein expression in the retina
using BAC transgenic mice from the GENSAT project. Among others, we identified
mouse lines in which the inhibitory cell types of the night vision and directional
selective circuit were selectively labeled. We quantified the stratification patterns
to predict potential synaptic connectivity between marked cells of different lines
and found that some of the lines enabled targeted recordings and imaging of cell
types from developing or mature retinal circuits. Our results suggest the potential
use of a stratification-based screening approach for characterizing neuronal circuitry
in other layered brain structures, such as the neocortex.
acknowledgement: This study was supported by Friedrich Miescher Institute funds, a
US Office of Naval Research Naval International Cooperative Opportunities in Science
and Technology Program grant, a Marie Curie Excellence grant, a National Center
for Competence in Research in Genetics grant and a European Union HEALTH-F2-223156
grant to B.R., and by National Institute of Neurological Disorders and Stroke contracts
N01NS02331 and HHSN271200723701C to N.H.
author:
- first_name: Sandra
full_name: Sandra Siegert
id: 36ACD32E-F248-11E8-B48F-1D18A9856A87
last_name: Siegert
orcid: 0000-0001-8635-0877
- first_name: Brigitte
full_name: Scherf, Brigitte G
last_name: Scherf
- first_name: Karina
full_name: Del Punta, Karina
last_name: Del Punta
- first_name: Nick
full_name: Didkovsky, Nick
last_name: Didkovsky
- first_name: Nathaniel
full_name: Heintz, Nathaniel M
last_name: Heintz
- first_name: Botond
full_name: Roska, Botond M
last_name: Roska
citation:
ama: Siegert S, Scherf B, Del Punta K, Didkovsky N, Heintz N, Roska B. Genetic address
book for retinal cell types. Nature Neuroscience. 2009;12(9):1197-1204.
doi:10.1038/nn.2370
apa: Siegert, S., Scherf, B., Del Punta, K., Didkovsky, N., Heintz, N., & Roska,
B. (2009). Genetic address book for retinal cell types. Nature Neuroscience.
Nature Publishing Group. https://doi.org/10.1038/nn.2370
chicago: Siegert, Sandra, Brigitte Scherf, Karina Del Punta, Nick Didkovsky, Nathaniel
Heintz, and Botond Roska. “Genetic Address Book for Retinal Cell Types.” Nature
Neuroscience. Nature Publishing Group, 2009. https://doi.org/10.1038/nn.2370.
ieee: S. Siegert, B. Scherf, K. Del Punta, N. Didkovsky, N. Heintz, and B. Roska,
“Genetic address book for retinal cell types,” Nature Neuroscience, vol.
12, no. 9. Nature Publishing Group, pp. 1197–1204, 2009.
ista: Siegert S, Scherf B, Del Punta K, Didkovsky N, Heintz N, Roska B. 2009. Genetic
address book for retinal cell types. Nature Neuroscience. 12(9), 1197–1204.
mla: Siegert, Sandra, et al. “Genetic Address Book for Retinal Cell Types.” Nature
Neuroscience, vol. 12, no. 9, Nature Publishing Group, 2009, pp. 1197–204,
doi:10.1038/nn.2370.
short: S. Siegert, B. Scherf, K. Del Punta, N. Didkovsky, N. Heintz, B. Roska, Nature
Neuroscience 12 (2009) 1197–1204.
date_created: 2018-12-11T11:54:04Z
date_published: 2009-09-01T00:00:00Z
date_updated: 2021-01-12T06:53:16Z
day: '01'
doi: 10.1038/nn.2370
extern: 1
intvolume: ' 12'
issue: '9'
month: '09'
page: 1197 - 1204
publication: Nature Neuroscience
publication_status: published
publisher: Nature Publishing Group
publist_id: '5312'
quality_controlled: 0
status: public
title: Genetic address book for retinal cell types
type: journal_article
volume: 12
year: '2009'
...
---
_id: '1799'
abstract:
- lang: eng
text: 'The detection of approaching objects, such as looming predators, is necessary
for survival. Which neurons and circuits mediate this function? We combined genetic
labeling of cell types, two-photon microscopy, electrophysiology and theoretical
modeling to address this question. We identify an approach-sensitive ganglion
cell type in the mouse retina, resolve elements of its afferent neural circuit,
and describe how these confer approach sensitivity on the ganglion cell. The circuit''s
essential building block is a rapid inhibitory pathway: it selectively suppresses
responses to non-approaching objects. This rapid inhibitory pathway, which includes
AII amacrine cells connected to bipolar cells through electrical synapses, was
previously described in the context of night-time vision. In the daytime conditions
of our experiments, the same pathway conveys signals in the reverse direction.
The dual use of a neural pathway in different physiological conditions illustrates
the efficiency with which several functions can be accommodated in a single circuit.'
acknowledgement: The study was supported by Friedrich Miescher Institute funds, a
US Office of Naval Research Naval International Cooperative Opportunities in Science
and Technology program grant, a Marie Curie Excellence Grant, a Human Frontier Science
Program Young Investigator grant, a National Centers of Competence in Research in
Genetics grant and a European Union HEALTH-F2-223156 grant to B.R., a Marie Curie
Postdoctoral Fellowship to T.A.M., the Centre National de la Recherche Scientifique
through the Unité Mixte de Recherche 8550 to R.A.d.S.
author:
- first_name: Thomas
full_name: Münch, Thomas A
last_name: Münch
- first_name: Ravá
full_name: Da Silveira, Ravá A
last_name: Da Silveira
- first_name: Sandra
full_name: Sandra Siegert
id: 36ACD32E-F248-11E8-B48F-1D18A9856A87
last_name: Siegert
orcid: 0000-0001-8635-0877
- first_name: Tim
full_name: Viney, Tim J
last_name: Viney
- first_name: Gautam
full_name: Awatramani, Gautam B
last_name: Awatramani
- first_name: Botond
full_name: Roska, Botond M
last_name: Roska
citation:
ama: Münch T, Da Silveira R, Siegert S, Viney T, Awatramani G, Roska B. Approach
sensitivity in the retina processed by a multifunctional neural circuit. Nature
Neuroscience. 2009;12(10):1308-1316. doi:10.1038/nn.2389
apa: Münch, T., Da Silveira, R., Siegert, S., Viney, T., Awatramani, G., & Roska,
B. (2009). Approach sensitivity in the retina processed by a multifunctional neural
circuit. Nature Neuroscience. Nature Publishing Group. https://doi.org/10.1038/nn.2389
chicago: Münch, Thomas, Ravá Da Silveira, Sandra Siegert, Tim Viney, Gautam Awatramani,
and Botond Roska. “Approach Sensitivity in the Retina Processed by a Multifunctional
Neural Circuit.” Nature Neuroscience. Nature Publishing Group, 2009. https://doi.org/10.1038/nn.2389.
ieee: T. Münch, R. Da Silveira, S. Siegert, T. Viney, G. Awatramani, and B. Roska,
“Approach sensitivity in the retina processed by a multifunctional neural circuit,”
Nature Neuroscience, vol. 12, no. 10. Nature Publishing Group, pp. 1308–1316,
2009.
ista: Münch T, Da Silveira R, Siegert S, Viney T, Awatramani G, Roska B. 2009. Approach
sensitivity in the retina processed by a multifunctional neural circuit. Nature
Neuroscience. 12(10), 1308–1316.
mla: Münch, Thomas, et al. “Approach Sensitivity in the Retina Processed by a Multifunctional
Neural Circuit.” Nature Neuroscience, vol. 12, no. 10, Nature Publishing
Group, 2009, pp. 1308–16, doi:10.1038/nn.2389.
short: T. Münch, R. Da Silveira, S. Siegert, T. Viney, G. Awatramani, B. Roska,
Nature Neuroscience 12 (2009) 1308–1316.
date_created: 2018-12-11T11:54:04Z
date_published: 2009-10-01T00:00:00Z
date_updated: 2021-01-12T06:53:16Z
day: '01'
doi: 10.1038/nn.2389
extern: 1
intvolume: ' 12'
issue: '10'
month: '10'
page: 1308 - 1316
publication: Nature Neuroscience
publication_status: published
publisher: Nature Publishing Group
publist_id: '5311'
quality_controlled: 0
status: public
title: Approach sensitivity in the retina processed by a multifunctional neural circuit
type: journal_article
volume: 12
year: '2009'
...
---
_id: '1825'
abstract:
- lang: eng
text: 'Many membrane channels and receptors exhibit adaptive, or desensitized, response
to a strong sustained input stimulus. A key mechanism that underlies this response
is the slow, activity-dependent removal of responding molecules to a pool which
is unavailable to respond immediately to the input. This mechanism is implemented
in different ways in various biological systems and has traditionally been studied
separately for each. Here we highlight the common aspects of this principle, shared
by many biological systems, and suggest a unifying theoretical framework. We study
theoretically a class of models which describes the general mechanism and allows
us to distinguish its universal from system-specific features. We show that under
general conditions, regardless of the details of kinetics, molecule availability
encodes an averaging over past activity and feeds back multiplicatively on the
system output. The kinetics of recovery from unavailability determines the effective
memory kernel inside the feedback branch, giving rise to a variety of system-specific
forms of adaptive response—precise or input-dependent, exponential or power-law—as
special cases of the same model. '
author:
- first_name: Tamar
full_name: Tamar Friedlander
id: 36A5845C-F248-11E8-B48F-1D18A9856A87
last_name: Friedlander
- first_name: Naama
full_name: Brenner, Naama
last_name: Brenner
citation:
ama: Friedlander T, Brenner N. Adaptive response by state-dependent inactivation.
PNAS. 2009;106(52):22558-22563. doi:10.1073/pnas.0902146106
apa: Friedlander, T., & Brenner, N. (2009). Adaptive response by state-dependent
inactivation. PNAS. National Academy of Sciences. https://doi.org/10.1073/pnas.0902146106
chicago: Friedlander, Tamar, and Naama Brenner. “Adaptive Response by State-Dependent
Inactivation.” PNAS. National Academy of Sciences, 2009. https://doi.org/10.1073/pnas.0902146106 .
ieee: T. Friedlander and N. Brenner, “Adaptive response by state-dependent inactivation,”
PNAS, vol. 106, no. 52. National Academy of Sciences, pp. 22558–22563,
2009.
ista: Friedlander T, Brenner N. 2009. Adaptive response by state-dependent inactivation.
PNAS. 106(52), 22558–22563.
mla: Friedlander, Tamar, and Naama Brenner. “Adaptive Response by State-Dependent
Inactivation.” PNAS, vol. 106, no. 52, National Academy of Sciences, 2009,
pp. 22558–63, doi:10.1073/pnas.0902146106
.
short: T. Friedlander, N. Brenner, PNAS 106 (2009) 22558–22563.
date_created: 2018-12-11T11:54:13Z
date_published: 2009-12-01T00:00:00Z
date_updated: 2021-01-12T06:53:26Z
day: '01'
doi: '10.1073/pnas.0902146106 '
extern: 1
intvolume: ' 106'
issue: '52'
main_file_link:
- open_access: '1'
url: http://www.pnas.org/content/106/52/22558.full.pdf
month: '12'
oa: 1
page: 22558 - 22563
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '5281'
quality_controlled: 0
status: public
title: Adaptive response by state-dependent inactivation
type: journal_article
volume: 106
year: '2009'
...
---
_id: '1971'
abstract:
- lang: eng
text: Complex I plays a central role in cellular energy production, coupling electron
transfer between NADH and quinone to proton translocation. The mechanism of this
highly efficient enzyme is currently unknown. Mitochondrial complex I is a major
source of reactive oxygen species, which may be one of the causes of aging. Dysfunction
of complex I is implicated in many human neurodegenerative diseases. We have determined
several x-ray structures of the oxidized and reduced hydrophilic domain of complex
I from Thermus thermophilus at up to 3.1 Å resolution. The structures reveal the
mode of interaction of complex I with NADH, explaining known kinetic data and
providing implications for the mechanism of reactive oxygen species production
at the flavin site of complex I. Bound metals were identified in the channel at
the interface with the frataxin-like subunit Nqo15, indicating possible iron-binding
sites. Conformational changes upon reduction of the complex involve adjustments
in the nucleotide-binding pocket, as well as small but significant shifts of several
α-helices at the interface with the membrane domain. These shifts are likely to
be driven by the reduction of nearby iron-sulfur clusters N2 and N6a/b. Cluster
N2 is the electron donor to quinone and is coordinated by unique motif involving
two consecutive (tandem) cysteines. An unprecedented "on/off switch"
(disconnection) of coordinating bonds between the tandem cysteines and this cluster
was observed upon reduction. Comparison of the structures suggests a novel mechanism
of coupling between electron transfer and proton translocation, combining conformational
changes and protonation/deprotonation of tandem cysteines.
acknowledgement: 'This work was supported by the Medical Research Council. '
author:
- first_name: John
full_name: Berrisford, John M
last_name: Berrisford
- first_name: Leonid A
full_name: Leonid Sazanov
id: 338D39FE-F248-11E8-B48F-1D18A9856A87
last_name: Sazanov
orcid: 0000-0002-0977-7989
citation:
ama: Berrisford J, Sazanov LA. Structural basis for the mechanism of respiratory
complex I. Journal of Biological Chemistry. 2009;284(43):29773-29783. doi:10.1074/jbc.M109.032144
apa: Berrisford, J., & Sazanov, L. A. (2009). Structural basis for the mechanism
of respiratory complex I. Journal of Biological Chemistry. American Society
for Biochemistry and Molecular Biology. https://doi.org/10.1074/jbc.M109.032144
chicago: Berrisford, John, and Leonid A Sazanov. “Structural Basis for the Mechanism
of Respiratory Complex I.” Journal of Biological Chemistry. American Society
for Biochemistry and Molecular Biology, 2009. https://doi.org/10.1074/jbc.M109.032144.
ieee: J. Berrisford and L. A. Sazanov, “Structural basis for the mechanism of respiratory
complex I,” Journal of Biological Chemistry, vol. 284, no. 43. American
Society for Biochemistry and Molecular Biology, pp. 29773–29783, 2009.
ista: Berrisford J, Sazanov LA. 2009. Structural basis for the mechanism of respiratory
complex I. Journal of Biological Chemistry. 284(43), 29773–29783.
mla: Berrisford, John, and Leonid A. Sazanov. “Structural Basis for the Mechanism
of Respiratory Complex I.” Journal of Biological Chemistry, vol. 284, no.
43, American Society for Biochemistry and Molecular Biology, 2009, pp. 29773–83,
doi:10.1074/jbc.M109.032144.
short: J. Berrisford, L.A. Sazanov, Journal of Biological Chemistry 284 (2009) 29773–29783.
date_created: 2018-12-11T11:54:59Z
date_published: 2009-10-23T00:00:00Z
date_updated: 2021-01-12T06:54:26Z
day: '23'
doi: 10.1074/jbc.M109.032144
extern: 1
intvolume: ' 284'
issue: '43'
month: '10'
page: 29773 - 29783
publication: Journal of Biological Chemistry
publication_status: published
publisher: American Society for Biochemistry and Molecular Biology
publist_id: '5114'
quality_controlled: 0
status: public
title: Structural basis for the mechanism of respiratory complex I
type: journal_article
volume: 284
year: '2009'
...
---
_id: '1983'
abstract:
- lang: eng
text: 'During many cellular processes such as cell division, polarization and motility,
the plasma membrane does not only represent a passive physical barrier, but also
provides a highly dynamic platform for the interplay between lipids, membrane
binding proteins and cytoskeletal elements. Even though many regulators of these
interactions are known, their mutual interdependence appears to be highly complex
and difficult to study in a living cell. Over the past few years, in vitro studies
on membrane-cytoskeleton interactions using biomimetic membranes turned out to
be extremely helpful to get better mechanistic insight into the dynamics of these
processes. In this review, we discuss some of the recent developments using in
vitro assays to dissect the role of the players involved: lipids in the membrane,
proteins binding to membranes and proteins binding to membrane proteins. We also
summarize advantages and disadvantages of supported lipid bilayers as model membrane.'
author:
- first_name: Martin
full_name: Martin Loose
id: 462D4284-F248-11E8-B48F-1D18A9856A87
last_name: Loose
orcid: 0000-0001-7309-9724
- first_name: Petra
full_name: 'Schwille, Petra '
last_name: Schwille
citation:
ama: Loose M, Schwille P. Biomimetic membrane systems to study cellular organization.
Journal of Structural Biology. 2009;168(1):143-151. doi:10.1016/j.jsb.2009.03.016
apa: Loose, M., & Schwille, P. (2009). Biomimetic membrane systems to study
cellular organization. Journal of Structural Biology. Academic Press. https://doi.org/10.1016/j.jsb.2009.03.016
chicago: Loose, Martin, and Petra Schwille. “Biomimetic Membrane Systems to Study
Cellular Organization.” Journal of Structural Biology. Academic Press,
2009. https://doi.org/10.1016/j.jsb.2009.03.016.
ieee: M. Loose and P. Schwille, “Biomimetic membrane systems to study cellular organization,”
Journal of Structural Biology, vol. 168, no. 1. Academic Press, pp. 143–151,
2009.
ista: Loose M, Schwille P. 2009. Biomimetic membrane systems to study cellular organization.
Journal of Structural Biology. 168(1), 143–151.
mla: Loose, Martin, and Petra Schwille. “Biomimetic Membrane Systems to Study Cellular
Organization.” Journal of Structural Biology, vol. 168, no. 1, Academic
Press, 2009, pp. 143–51, doi:10.1016/j.jsb.2009.03.016.
short: M. Loose, P. Schwille, Journal of Structural Biology 168 (2009) 143–151.
date_created: 2018-12-11T11:55:03Z
date_published: 2009-10-01T00:00:00Z
date_updated: 2021-01-12T06:54:30Z
day: '01'
doi: 10.1016/j.jsb.2009.03.016
extern: 1
intvolume: ' 168'
issue: '1'
month: '10'
page: 143 - 151
publication: Journal of Structural Biology
publication_status: published
publisher: Academic Press
publist_id: '5099'
quality_controlled: 0
status: public
title: Biomimetic membrane systems to study cellular organization
type: journal_article
volume: 168
year: '2009'
...
---
_id: '1984'
abstract:
- lang: eng
text: In animal and plant cells, mitotic chromatin locally generates microtubules
that self-organize into a mitotic spindle, and its dimensions and bipolar symmetry
are essential for accurate chromosome segregation. By immobilizing microscopic
chromatin-coated beads on slide surfaces using a microprinting technique, we have
examined the effect of chromatin on the dimensions and symmetry of spindles in
Xenopus laevis cytoplasmic extracts. While circular spots with diameters around
14-18 μm trigger bipolar spindle formation, larger spots generate an incorrect
number of poles. We also examined lines of chromatin with various dimensions.
Their length determined the number of poles that formed, with a 6 × 18 μm rectangular
patch generating normal spindle morphology. Around longer lines, multiple poles
formed and the structures were disorganized. While lines thinner than 10 μm generated
symmetric structures, thicker lines induced the formation of asymmetric structures
where all microtubules are on the same side of the line. Our results show that
chromatin defines spindle shape and orientation. For a video summary of this article,
see the PaperFlick file available with the online Supplemental Data.
acknowledgement: This work was supported by EU contract LSHG-CT-2004-503568 ComBio,
the Spanish ministry of education (M.M.C.), and EU-STREP active BioMics (A.D.).
Research in the Nedelec lab is funded by the Center for Modeling and Simulation
in the Biosciences (http://www.bioms.de), the Volkswagenstiftung, and Human Frontier
Science Program grant RGY84.
author:
- first_name: Ana
full_name: Dinarina, Ana
last_name: Dinarina
- first_name: Céline
full_name: Pugieux, Céline
last_name: Pugieux
- first_name: Maria
full_name: Corral, Maria M
last_name: Corral
- first_name: Martin
full_name: Martin Loose
id: 462D4284-F248-11E8-B48F-1D18A9856A87
last_name: Loose
orcid: 0000-0001-7309-9724
- first_name: Joachim
full_name: Spatz, Joachim P
last_name: Spatz
- first_name: Éric
full_name: Karsenti, Éric
last_name: Karsenti
- first_name: François
full_name: Nédélec, François J
last_name: Nédélec
citation:
ama: Dinarina A, Pugieux C, Corral M, et al. Chromatin shapes the mitotic spindle.
Cell. 2009;138(3):502-513. doi:10.1016/j.cell.2009.05.027
apa: Dinarina, A., Pugieux, C., Corral, M., Loose, M., Spatz, J., Karsenti, É.,
& Nédélec, F. (2009). Chromatin shapes the mitotic spindle. Cell. Cell
Press. https://doi.org/10.1016/j.cell.2009.05.027
chicago: Dinarina, Ana, Céline Pugieux, Maria Corral, Martin Loose, Joachim Spatz,
Éric Karsenti, and François Nédélec. “Chromatin Shapes the Mitotic Spindle.” Cell.
Cell Press, 2009. https://doi.org/10.1016/j.cell.2009.05.027.
ieee: A. Dinarina et al., “Chromatin shapes the mitotic spindle,” Cell,
vol. 138, no. 3. Cell Press, pp. 502–513, 2009.
ista: Dinarina A, Pugieux C, Corral M, Loose M, Spatz J, Karsenti É, Nédélec F.
2009. Chromatin shapes the mitotic spindle. Cell. 138(3), 502–513.
mla: Dinarina, Ana, et al. “Chromatin Shapes the Mitotic Spindle.” Cell,
vol. 138, no. 3, Cell Press, 2009, pp. 502–13, doi:10.1016/j.cell.2009.05.027.
short: A. Dinarina, C. Pugieux, M. Corral, M. Loose, J. Spatz, É. Karsenti, F. Nédélec,
Cell 138 (2009) 502–513.
date_created: 2018-12-11T11:55:03Z
date_published: 2009-08-07T00:00:00Z
date_updated: 2021-01-12T06:54:30Z
day: '07'
doi: 10.1016/j.cell.2009.05.027
extern: 1
intvolume: ' 138'
issue: '3'
month: '08'
page: 502 - 513
publication: Cell
publication_status: published
publisher: Cell Press
publist_id: '5100'
quality_controlled: 0
status: public
title: Chromatin shapes the mitotic spindle
type: journal_article
volume: 138
year: '2009'
...