---
_id: '2932'
abstract:
- lang: eng
  text: |+
    We describe a new implementation of the Edmonds’s algorithm for computing a perfect matching of minimum cost, to which we refer as Blossom V. A key feature of our implementation is a combination of two ideas that were shown to be effective for this problem: the “variable dual updates” approach of Cook and Rohe (INFORMS J Comput 11(2):138–148, 1999) and the use of priority queues. We achieve this by maintaining an auxiliary graph whose nodes correspond to alternating trees in the Edmonds’s algorithm. While our use of priority queues does not improve the worst-case complexity, it appears to lead to an efficient technique. In the majority of our tests Blossom V outperformed previous implementations of Cook and Rohe (INFORMS J Comput 11(2):138–148, 1999) and Mehlhorn and Schäfer (J Algorithmics Exp (JEA) 7:4, 2002), sometimes by an order of magnitude. We also show that for large VLSI instances it is beneficial to update duals by solving a linear program, contrary to a conjecture by Cook and Rohe.

author:
- first_name: Vladimir
  full_name: Vladimir Kolmogorov
  id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
  last_name: Kolmogorov
citation:
  ama: 'Kolmogorov V. Blossom V: A new implementation of a minimum cost perfect matching
    algorithm. <i>Mathematical Programming Computation</i>. 2009;1(1):43-67. doi:<a
    href="https://doi.org/10.1007/s12532-009-0002-8">10.1007/s12532-009-0002-8</a>'
  apa: 'Kolmogorov, V. (2009). Blossom V: A new implementation of a minimum cost perfect
    matching algorithm. <i>Mathematical Programming Computation</i>. Springer. <a
    href="https://doi.org/10.1007/s12532-009-0002-8">https://doi.org/10.1007/s12532-009-0002-8</a>'
  chicago: 'Kolmogorov, Vladimir. “Blossom V: A New Implementation of a Minimum Cost
    Perfect Matching Algorithm.” <i>Mathematical Programming Computation</i>. Springer,
    2009. <a href="https://doi.org/10.1007/s12532-009-0002-8">https://doi.org/10.1007/s12532-009-0002-8</a>.'
  ieee: 'V. Kolmogorov, “Blossom V: A new implementation of a minimum cost perfect
    matching algorithm,” <i>Mathematical Programming Computation</i>, vol. 1, no.
    1. Springer, pp. 43–67, 2009.'
  ista: 'Kolmogorov V. 2009. Blossom V: A new implementation of a minimum cost perfect
    matching algorithm. Mathematical Programming Computation. 1(1), 43–67.'
  mla: 'Kolmogorov, Vladimir. “Blossom V: A New Implementation of a Minimum Cost Perfect
    Matching Algorithm.” <i>Mathematical Programming Computation</i>, vol. 1, no.
    1, Springer, 2009, pp. 43–67, doi:<a href="https://doi.org/10.1007/s12532-009-0002-8">10.1007/s12532-009-0002-8</a>.'
  short: V. Kolmogorov, Mathematical Programming Computation 1 (2009) 43–67.
date_created: 2018-12-11T12:00:25Z
date_published: 2009-07-01T00:00:00Z
date_updated: 2021-01-12T07:00:47Z
day: '01'
doi: 10.1007/s12532-009-0002-8
extern: 1
intvolume: '         1'
issue: '1'
month: '07'
page: 43 - 67
publication: Mathematical Programming Computation
publication_status: published
publisher: Springer
publist_id: '3804'
quality_controlled: 0
status: public
title: 'Blossom V: A new implementation of a minimum cost perfect matching algorithm'
type: journal_article
volume: 1
year: '2009'
...
...
---
_id: '3046'
abstract:
- lang: eng
  text: Plant-parasitic nematodes are destructive plant pathogens that cause significant
    yield losses. They induce highly specialized feeding sites (NFS) in infected plant
    roots from which they withdraw nutrients. In order to establish these NFS, it
    is thought that the nematodes manipulate the molecular and physiological pathways
    of their hosts. Evidence is accumulating that the plant signalling molecule auxin
    is involved in the initiation and development of the feeding sites of sedentary
    plant-parasitic nematodes. Intercellular transport of auxin is essential for various
    aspects of plant growth and development. Here, we analysed the spatial and temporal
    expression of PIN auxin transporters during the early events of NFS establishment
    using promoter-GUS/GFP fusion lines. Additionally, single and double pin mutants
    were used in infection studies to analyse the role of the different PIN proteins
    during cyst nematode infection. Based on our results, we postulate a model in
    which PIN1-mediated auxin transport is needed to deliver auxin to the initial
    syncytial cell, whereas PIN3 and PIN4 distribute the accumulated auxin laterally
    and are involved in the radial expansion of the NFS. Our data demonstrate that
    cyst nematodes are able to hijack the auxin distribution network in order to facilitate
    the infection process. © 2009 Grunewald et al
author:
- first_name: Wim
  full_name: Grunewald, Wim
  last_name: Grunewald
- first_name: Bernard
  full_name: Cannoot, Bernard
  last_name: Cannoot
- first_name: Jirí
  full_name: Jirí Friml
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Godelieve
  full_name: Gheysen, Godelieve
  last_name: Gheysen
citation:
  ama: Grunewald W, Cannoot B, Friml J, Gheysen G. Parasitic nematodes modulate PIN
    mediated auxin transport to facilitate infection. <i>PLoS Pathogens</i>. 2009;5(1).
    doi:<a href="https://doi.org/ 10.1371/journal.ppat.1000266"> 10.1371/journal.ppat.1000266</a>
  apa: Grunewald, W., Cannoot, B., Friml, J., &#38; Gheysen, G. (2009). Parasitic
    nematodes modulate PIN mediated auxin transport to facilitate infection. <i>PLoS
    Pathogens</i>. Public Library of Science. <a href="https://doi.org/ 10.1371/journal.ppat.1000266">https://doi.org/
    10.1371/journal.ppat.1000266</a>
  chicago: Grunewald, Wim, Bernard Cannoot, Jiří Friml, and Godelieve Gheysen. “Parasitic
    Nematodes Modulate PIN Mediated Auxin Transport to Facilitate Infection.” <i>PLoS
    Pathogens</i>. Public Library of Science, 2009. <a href="https://doi.org/ 10.1371/journal.ppat.1000266">https://doi.org/
    10.1371/journal.ppat.1000266</a>.
  ieee: W. Grunewald, B. Cannoot, J. Friml, and G. Gheysen, “Parasitic nematodes modulate
    PIN mediated auxin transport to facilitate infection,” <i>PLoS Pathogens</i>,
    vol. 5, no. 1. Public Library of Science, 2009.
  ista: Grunewald W, Cannoot B, Friml J, Gheysen G. 2009. Parasitic nematodes modulate
    PIN mediated auxin transport to facilitate infection. PLoS Pathogens. 5(1).
  mla: Grunewald, Wim, et al. “Parasitic Nematodes Modulate PIN Mediated Auxin Transport
    to Facilitate Infection.” <i>PLoS Pathogens</i>, vol. 5, no. 1, Public Library
    of Science, 2009, doi:<a href="https://doi.org/ 10.1371/journal.ppat.1000266">
    10.1371/journal.ppat.1000266</a>.
  short: W. Grunewald, B. Cannoot, J. Friml, G. Gheysen, PLoS Pathogens 5 (2009).
date_created: 2018-12-11T12:01:03Z
date_published: 2009-01-01T00:00:00Z
date_updated: 2021-01-12T07:40:40Z
day: '01'
doi: ' 10.1371/journal.ppat.1000266'
extern: 1
intvolume: '         5'
issue: '1'
month: '01'
publication: PLoS Pathogens
publication_status: published
publisher: Public Library of Science
publist_id: '3656'
quality_controlled: 0
status: public
title: Parasitic nematodes modulate PIN mediated auxin transport to facilitate infection
type: journal_article
volume: 5
year: '2009'
...
---
_id: '3047'
abstract:
- lang: eng
  text: "\n\nAuxin transport is mediated at the cellular level by three independent
    mechanisms that are characterised by the PIN-formed (PIN), P-glycoprotein (ABCB/PGP)
    and AUX/LAX transport proteins. The PIN and ABCB transport proteins, best represented
    by PIN1 and ABCB19 (PGP19), have been shown to coordinately regulate auxin efflux.
    When PIN1 and ABCB19 coincide on the plasma membrane, their interaction enhances
    the rate and specificity of auxin efflux and the dynamic cycling of PIN1 is reduced.
    However, ABCB19 function is not regulated by the dynamic cellular trafficking
    mechanisms that regulate PIN1 in apical tissues, as localisation of ABCB19 on
    the plasma membrane was not inhibited by short-term treatments with latrunculin
    B, oryzalin, brefeldin A (BFA) or wortmannin - all of which have been shown to
    alter PIN1 and/or PIN2 plasma membrane localisation. When taken up by endocytosis,
    the styryl dye FM4-64 labels diffuse rather than punctuate intracellular bodies
    in abcb19 (pgp19), and some aggregations of PIN1 induced by short-term BFA treatment
    did not disperse after BFA washout in abcb19. Although the subcellular localisations
    of ABCB19 and PIN1 in the reciprocal mutant backgrounds were like those in wild
    type, PIN1 plasma membrane localisation in abcb19 roots was more easily perturbed
    by the detergent Triton X-100, but not other non-ionic detergents. ABCB19 is stably
    associated with sterol/sphingolipid-enriched membrane fractions containing BIG/TIR3
    and partitions into Triton X-100 detergent-resistant membrane (DRM) fractions.
    In the wild type, PIN1 was also present in DRMs, but was less abundant in abcb19
    DRMs. These observations suggested a rationale for the observed lack of auxin
    transport activity when PIN1 is expressed in a non-plant heterologous system.
    PIN1 was therefore expressed in Schizosaccharomyces pombe, which has plant-like
    sterol-enriched microdomains, and catalysed auxin transport in these cells. These
    data suggest that ABCB19 stabilises PIN1 localisation at the plasma membrane in
    discrete cellular subdomains where PIN1 and ABCB19 expression overlaps. "
author:
- first_name: Boosaree
  full_name: Titapiwatanakun, Boosaree
  last_name: Titapiwatanakun
- first_name: Joshua
  full_name: Blakeslee, Joshua
  last_name: Blakeslee
- first_name: Anindita
  full_name: Bandyopadhyay, Anindita
  last_name: Bandyopadhyay
- first_name: Haibing
  full_name: Yang, Haibing
  last_name: Yang
- first_name: Jozef
  full_name: Mravec, Jozef
  last_name: Mravec
- first_name: Michael
  full_name: Sauer, Michael
  last_name: Sauer
- first_name: Yan
  full_name: Cheng, Yan
  last_name: Cheng
- first_name: Jiří
  full_name: Adamec, Jiří
  last_name: Adamec
- first_name: Akitomo
  full_name: Nagashima, Akitomo
  last_name: Nagashima
- first_name: Markus
  full_name: Geisler, Markus
  last_name: Geisler
- first_name: Tatsuya
  full_name: Sakai, Tatsuya
  last_name: Sakai
- first_name: Jirí
  full_name: Jirí Friml
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Wendy
  full_name: Peer, Wendy A
  last_name: Peer
- first_name: Angus
  full_name: Murphy, Angus S
  last_name: Murphy
citation:
  ama: Titapiwatanakun B, Blakeslee J, Bandyopadhyay A, et al. ABCB19 PGP19 stabilises
    PIN1 in membrane microdomains in Arabidopsis. <i>Plant Journal</i>. 2009;57(1):27-44.
    doi:<a href="https://doi.org/10.1111/j.1365-313X.2008.03668.x">10.1111/j.1365-313X.2008.03668.x</a>
  apa: Titapiwatanakun, B., Blakeslee, J., Bandyopadhyay, A., Yang, H., Mravec, J.,
    Sauer, M., … Murphy, A. (2009). ABCB19 PGP19 stabilises PIN1 in membrane microdomains
    in Arabidopsis. <i>Plant Journal</i>. Wiley-Blackwell. <a href="https://doi.org/10.1111/j.1365-313X.2008.03668.x">https://doi.org/10.1111/j.1365-313X.2008.03668.x</a>
  chicago: Titapiwatanakun, Boosaree, Joshua Blakeslee, Anindita Bandyopadhyay, Haibing
    Yang, Jozef Mravec, Michael Sauer, Yan Cheng, et al. “ABCB19 PGP19 Stabilises
    PIN1 in Membrane Microdomains in Arabidopsis.” <i>Plant Journal</i>. Wiley-Blackwell,
    2009. <a href="https://doi.org/10.1111/j.1365-313X.2008.03668.x">https://doi.org/10.1111/j.1365-313X.2008.03668.x</a>.
  ieee: B. Titapiwatanakun <i>et al.</i>, “ABCB19 PGP19 stabilises PIN1 in membrane
    microdomains in Arabidopsis,” <i>Plant Journal</i>, vol. 57, no. 1. Wiley-Blackwell,
    pp. 27–44, 2009.
  ista: Titapiwatanakun B, Blakeslee J, Bandyopadhyay A, Yang H, Mravec J, Sauer M,
    Cheng Y, Adamec J, Nagashima A, Geisler M, Sakai T, Friml J, Peer W, Murphy A.
    2009. ABCB19 PGP19 stabilises PIN1 in membrane microdomains in Arabidopsis. Plant
    Journal. 57(1), 27–44.
  mla: Titapiwatanakun, Boosaree, et al. “ABCB19 PGP19 Stabilises PIN1 in Membrane
    Microdomains in Arabidopsis.” <i>Plant Journal</i>, vol. 57, no. 1, Wiley-Blackwell,
    2009, pp. 27–44, doi:<a href="https://doi.org/10.1111/j.1365-313X.2008.03668.x">10.1111/j.1365-313X.2008.03668.x</a>.
  short: B. Titapiwatanakun, J. Blakeslee, A. Bandyopadhyay, H. Yang, J. Mravec, M.
    Sauer, Y. Cheng, J. Adamec, A. Nagashima, M. Geisler, T. Sakai, J. Friml, W. Peer,
    A. Murphy, Plant Journal 57 (2009) 27–44.
date_created: 2018-12-11T12:01:03Z
date_published: 2009-01-01T00:00:00Z
date_updated: 2021-01-12T07:40:40Z
day: '01'
doi: 10.1111/j.1365-313X.2008.03668.x
extern: 1
intvolume: '        57'
issue: '1'
month: '01'
page: 27 - 44
publication: Plant Journal
publication_status: published
publisher: Wiley-Blackwell
publist_id: '3655'
quality_controlled: 0
status: public
title: ABCB19 PGP19 stabilises PIN1 in membrane microdomains in Arabidopsis
type: journal_article
volume: 57
year: '2009'
...
---
_id: '3048'
abstract:
- lang: eng
  text: Endocytic vesicle trafficking is crucial for regulating activity and localization
    of plasma membrane components, but the process is still poorly genetically defined
    in plants. Membrane proteins of the PIN-FORMED (PIN) family exhibit polar localization
    in plant cells and facilitate cellular efflux of the plant hormone auxin, thereby
    regulating multiple developmental processes [1, 2]. PIN proteins undergo constitutive
    endocytosis and GNOM ARF GEF-dependent recycling [3-5], and their localization
    is under extensive regulation by developmental and environmental cues [6-9]. We
    designed a fluorescence imaging-based screen to identify Arabidopsis thaliana
    mutants defective in internalization of proteins including PINs from the plasma
    membrane. We identified three mutant loci, BFA-visualized endocytic trafficking
    defective1 (ben1) through ben3 that do not efficiently accumulate PIN1-GFP in
    intracellular compartments after inhibition of recycling and secretion by fungal
    toxin brefeldin A (BFA). Fine mapping revealed that BEN1 encodes an ARF GEF vesicle
    trafficking regulator from the functionally uncharacterized BIG class. ben1 mutant
    has been previously implicated in pathogen response [10] and shows cell polarity,
    BFA sensitivity, and growth defects. BEN1 is involved in endocytosis of plasma
    membrane proteins and localizes to early endocytic compartments distinct from
    GNOM-positive endosomes. Our results identify BEN1 as the ARF GEF mediating early
    endosomal traffic.
author:
- first_name: Hirokazu
  full_name: Tanaka, Hirokazu
  last_name: Tanaka
- first_name: Saeko
  full_name: Kitakura, Saeko
  last_name: Kitakura
- first_name: Riet
  full_name: De Rycke, Riet M
  last_name: De Rycke
- first_name: Ruth
  full_name: De Groodt, Ruth
  last_name: De Groodt
- first_name: Jirí
  full_name: Jirí Friml
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: Tanaka H, Kitakura S, De Rycke R, De Groodt R, Friml J. Fluorescence imaging
    based screen identifies ARF GEF component of early endosomal trafficking. <i>Current
    Biology</i>. 2009;19(5):391-397. doi:<a href="https://doi.org/10.1016/j.cub.2009.01.057">10.1016/j.cub.2009.01.057</a>
  apa: Tanaka, H., Kitakura, S., De Rycke, R., De Groodt, R., &#38; Friml, J. (2009).
    Fluorescence imaging based screen identifies ARF GEF component of early endosomal
    trafficking. <i>Current Biology</i>. Cell Press. <a href="https://doi.org/10.1016/j.cub.2009.01.057">https://doi.org/10.1016/j.cub.2009.01.057</a>
  chicago: Tanaka, Hirokazu, Saeko Kitakura, Riet De Rycke, Ruth De Groodt, and Jiří
    Friml. “Fluorescence Imaging Based Screen Identifies ARF GEF Component of Early
    Endosomal Trafficking.” <i>Current Biology</i>. Cell Press, 2009. <a href="https://doi.org/10.1016/j.cub.2009.01.057">https://doi.org/10.1016/j.cub.2009.01.057</a>.
  ieee: H. Tanaka, S. Kitakura, R. De Rycke, R. De Groodt, and J. Friml, “Fluorescence
    imaging based screen identifies ARF GEF component of early endosomal trafficking,”
    <i>Current Biology</i>, vol. 19, no. 5. Cell Press, pp. 391–397, 2009.
  ista: Tanaka H, Kitakura S, De Rycke R, De Groodt R, Friml J. 2009. Fluorescence
    imaging based screen identifies ARF GEF component of early endosomal trafficking.
    Current Biology. 19(5), 391–397.
  mla: Tanaka, Hirokazu, et al. “Fluorescence Imaging Based Screen Identifies ARF
    GEF Component of Early Endosomal Trafficking.” <i>Current Biology</i>, vol. 19,
    no. 5, Cell Press, 2009, pp. 391–97, doi:<a href="https://doi.org/10.1016/j.cub.2009.01.057">10.1016/j.cub.2009.01.057</a>.
  short: H. Tanaka, S. Kitakura, R. De Rycke, R. De Groodt, J. Friml, Current Biology
    19 (2009) 391–397.
date_created: 2018-12-11T12:01:03Z
date_published: 2009-03-10T00:00:00Z
date_updated: 2021-01-12T07:40:41Z
day: '10'
doi: 10.1016/j.cub.2009.01.057
extern: 1
intvolume: '        19'
issue: '5'
month: '03'
page: 391 - 397
publication: Current Biology
publication_status: published
publisher: Cell Press
publist_id: '3653'
quality_controlled: 0
status: public
title: Fluorescence imaging based screen identifies ARF GEF component of early endosomal
  trafficking
type: journal_article
volume: 19
year: '2009'
...
---
_id: '3049'
abstract:
- lang: eng
  text: Postembryonic de novo organogenesis represents an important competence evolved
    in plants that allows their physiological and developmental adaptation to changing
    environmental conditions. The phytohormones auxin and cytokinin (CK) are important
    regulators of the developmental fate of pluripotent plant cells. However, the
    molecular nature of their interaction(s) in control of plant organogenesis is
    largely unknown. Here, we show that CK modulates auxin-induced organogenesis (AIO)
    via regulation of the efflux-dependent intercellular auxin distribution. We used
    the hypocotyl explants-based in vitro system to study the mechanism underlying
    de novo organogenesis. We show that auxin, but not CK, is capable of triggering
    organogenesis in hypocotyl explants. The AIO is accompanied by endogenous CK production
    and tissue-specific activation of CK signaling. CK affects differential auxin
    distribution, and the CK-mediated modulation of organogenesis is simulated by
    inhibition of polar auxin transport. CK reduces auxin efflux from cultured tobacco
    cells and regulates expression of auxin efflux carriers from the PIN family in
    hypocotyl explants. Moreover, endogenous CK levels influence PIN transcription
    and are necessary to maintain intercellular auxin distribution in planta. Based
    on these findings, we propose a model in which auxin acts as a trigger of the
    organogenic processes, whose output is modulated by the endogenously produced
    CKs. We propose that an important mechanism of this CK action is its effect on
    auxin distribution via regulation of expression of auxin efflux carriers.
author:
- first_name: Markéta
  full_name: Pernisová, Markéta
  last_name: Pernisová
- first_name: Petr
  full_name: Klíma, Petr
  last_name: Klíma
- first_name: Jakub
  full_name: Horák, Jakub
  last_name: Horák
- first_name: Martina
  full_name: Válková, Martina
  last_name: Válková
- first_name: Jiří
  full_name: Malbeck, Jiří
  last_name: Malbeck
- first_name: Přemysl
  full_name: Souček, Přemysl
  last_name: Souček
- first_name: Pavel
  full_name: Reichman, Pavel
  last_name: Reichman
- first_name: Klára
  full_name: Hoyerová, Klára
  last_name: Hoyerová
- first_name: Jaroslava
  full_name: Dubová, Jaroslava
  last_name: Dubová
- first_name: Jirí
  full_name: Jirí Friml
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Eva
  full_name: Zažímalová, Eva
  last_name: Zažímalová
- first_name: Jan
  full_name: Hejátko, Jan
  last_name: Hejátko
citation:
  ama: Pernisová M, Klíma P, Horák J, et al. Cytokinins modulate auxin induced organogenesis
    in plants via regulation of the auxin efflux. <i>PNAS</i>. 2009;106(9):3609-3614.
    doi:<a href="https://doi.org/10.1073/pnas.0811539106">10.1073/pnas.0811539106</a>
  apa: Pernisová, M., Klíma, P., Horák, J., Válková, M., Malbeck, J., Souček, P.,
    … Hejátko, J. (2009). Cytokinins modulate auxin induced organogenesis in plants
    via regulation of the auxin efflux. <i>PNAS</i>. National Academy of Sciences.
    <a href="https://doi.org/10.1073/pnas.0811539106">https://doi.org/10.1073/pnas.0811539106</a>
  chicago: Pernisová, Markéta, Petr Klíma, Jakub Horák, Martina Válková, Jiří Malbeck,
    Přemysl Souček, Pavel Reichman, et al. “Cytokinins Modulate Auxin Induced Organogenesis
    in Plants via Regulation of the Auxin Efflux.” <i>PNAS</i>. National Academy of
    Sciences, 2009. <a href="https://doi.org/10.1073/pnas.0811539106">https://doi.org/10.1073/pnas.0811539106</a>.
  ieee: M. Pernisová <i>et al.</i>, “Cytokinins modulate auxin induced organogenesis
    in plants via regulation of the auxin efflux,” <i>PNAS</i>, vol. 106, no. 9. National
    Academy of Sciences, pp. 3609–3614, 2009.
  ista: Pernisová M, Klíma P, Horák J, Válková M, Malbeck J, Souček P, Reichman P,
    Hoyerová K, Dubová J, Friml J, Zažímalová E, Hejátko J. 2009. Cytokinins modulate
    auxin induced organogenesis in plants via regulation of the auxin efflux. PNAS.
    106(9), 3609–3614.
  mla: Pernisová, Markéta, et al. “Cytokinins Modulate Auxin Induced Organogenesis
    in Plants via Regulation of the Auxin Efflux.” <i>PNAS</i>, vol. 106, no. 9, National
    Academy of Sciences, 2009, pp. 3609–14, doi:<a href="https://doi.org/10.1073/pnas.0811539106">10.1073/pnas.0811539106</a>.
  short: M. Pernisová, P. Klíma, J. Horák, M. Válková, J. Malbeck, P. Souček, P. Reichman,
    K. Hoyerová, J. Dubová, J. Friml, E. Zažímalová, J. Hejátko, PNAS 106 (2009) 3609–3614.
date_created: 2018-12-11T12:01:04Z
date_published: 2009-03-03T00:00:00Z
date_updated: 2021-01-12T07:40:41Z
day: '03'
doi: 10.1073/pnas.0811539106
extern: 1
intvolume: '       106'
issue: '9'
month: '03'
page: 3609 - 3614
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '3654'
quality_controlled: 0
status: public
title: Cytokinins modulate auxin induced organogenesis in plants via regulation of
  the auxin efflux
type: journal_article
volume: 106
year: '2009'
...
---
_id: '3050'
abstract:
- lang: eng
  text: 'Plant development is governed by signaling molecules called phytohormones.
    Typically, in certain developmental processes more than 1 hormone is implicated
    and, thus, coordination of their overlapping activities is crucial for correct
    plant development. However, molecular mechanisms underlying the hormonal crosstalk
    are only poorly understood. Multiple hormones including cytokinin and auxin have
    been implicated in the regulation of root development. Here we dissect the roles
    of cytokinin in modulating growth of the primary root. We show that cytokinin
    effect on root elongation occurs through ethylene signaling whereas cytokinin
    effect on the root meristem size involves ethylene-independent modulation of transport-dependent
    asymmetric auxin distribution. Exogenous or endogenous modification of cytokinin
    levels and cytokinin signaling lead to specific changes in transcription of several
    auxin efflux carrier genes from the PIN family having a direct impact on auxin
    efflux from cultured cells and on auxin distribution in the root apex. We propose
    a novel model for cytokinin action in regulating root growth: Cytokinin influences
    cell-to-cell auxin transport by modification of expression of several auxin transport
    components and thus modulates auxin distribution important for regulation of activity
    and size of the root meristem.'
author:
- first_name: Kamil
  full_name: Růžička, Kamil
  last_name: Růžička
- first_name: Mária
  full_name: Šimášková, Mária
  last_name: Šimášková
- first_name: Jérôme
  full_name: Duclercq, Jérôme
  last_name: Duclercq
- first_name: Jan
  full_name: Petrášek, Jan
  last_name: Petrášek
- first_name: Eva
  full_name: Zažímalová, Eva
  last_name: Zažímalová
- first_name: Sibu
  full_name: Sibu Simon
  id: 4542EF9A-F248-11E8-B48F-1D18A9856A87
  last_name: Simon
  orcid: 0000-0002-1998-6741
- first_name: Jirí
  full_name: Jirí Friml
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Marc
  full_name: Van Montagu, Marc C
  last_name: Van Montagu
- first_name: Eva
  full_name: Eva Benková
  id: 38F4F166-F248-11E8-B48F-1D18A9856A87
  last_name: Benková
  orcid: 0000-0002-8510-9739
citation:
  ama: Růžička K, Šimášková M, Duclercq J, et al. Cytokinin regulates root meristem
    activity via modulation of the polar auxin transport. <i>PNAS</i>. 2009;106(11):4284-4289.
    doi:<a href="https://doi.org/10.1073/pnas.0900060106">10.1073/pnas.0900060106</a>
  apa: Růžička, K., Šimášková, M., Duclercq, J., Petrášek, J., Zažímalová, E., Simon,
    S., … Benková, E. (2009). Cytokinin regulates root meristem activity via modulation
    of the polar auxin transport. <i>PNAS</i>. National Academy of Sciences. <a href="https://doi.org/10.1073/pnas.0900060106">https://doi.org/10.1073/pnas.0900060106</a>
  chicago: Růžička, Kamil, Mária Šimášková, Jérôme Duclercq, Jan Petrášek, Eva Zažímalová,
    Sibu Simon, Jiří Friml, Marc Van Montagu, and Eva Benková. “Cytokinin Regulates
    Root Meristem Activity via Modulation of the Polar Auxin Transport.” <i>PNAS</i>.
    National Academy of Sciences, 2009. <a href="https://doi.org/10.1073/pnas.0900060106">https://doi.org/10.1073/pnas.0900060106</a>.
  ieee: K. Růžička <i>et al.</i>, “Cytokinin regulates root meristem activity via
    modulation of the polar auxin transport,” <i>PNAS</i>, vol. 106, no. 11. National
    Academy of Sciences, pp. 4284–4289, 2009.
  ista: Růžička K, Šimášková M, Duclercq J, Petrášek J, Zažímalová E, Simon S, Friml
    J, Van Montagu M, Benková E. 2009. Cytokinin regulates root meristem activity
    via modulation of the polar auxin transport. PNAS. 106(11), 4284–4289.
  mla: Růžička, Kamil, et al. “Cytokinin Regulates Root Meristem Activity via Modulation
    of the Polar Auxin Transport.” <i>PNAS</i>, vol. 106, no. 11, National Academy
    of Sciences, 2009, pp. 4284–89, doi:<a href="https://doi.org/10.1073/pnas.0900060106">10.1073/pnas.0900060106</a>.
  short: K. Růžička, M. Šimášková, J. Duclercq, J. Petrášek, E. Zažímalová, S. Simon,
    J. Friml, M. Van Montagu, E. Benková, PNAS 106 (2009) 4284–4289.
date_created: 2018-12-11T12:01:04Z
date_published: 2009-03-17T00:00:00Z
date_updated: 2021-01-12T07:40:42Z
day: '17'
doi: 10.1073/pnas.0900060106
extern: 1
intvolume: '       106'
issue: '11'
month: '03'
page: 4284 - 4289
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '3652'
quality_controlled: 0
status: public
title: Cytokinin regulates root meristem activity via modulation of the polar auxin
  transport
type: journal_article
volume: 106
year: '2009'
...
---
_id: '3051'
article_type: original
author:
- first_name: Dolf
  full_name: Weijers, Dolf
  last_name: Weijers
- first_name: Jirí
  full_name: Friml, Jirí
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: 'Weijers D, Friml J. SnapShot: Auxin signaling and transport. <i>Cell</i>.
    2009;136(6):1172-1172. doi:<a href="https://doi.org/10.1016/j.cell.2009.03.009">10.1016/j.cell.2009.03.009</a>'
  apa: 'Weijers, D., &#38; Friml, J. (2009). SnapShot: Auxin signaling and transport.
    <i>Cell</i>. Cell Press. <a href="https://doi.org/10.1016/j.cell.2009.03.009">https://doi.org/10.1016/j.cell.2009.03.009</a>'
  chicago: 'Weijers, Dolf, and Jiří Friml. “SnapShot: Auxin Signaling and Transport.”
    <i>Cell</i>. Cell Press, 2009. <a href="https://doi.org/10.1016/j.cell.2009.03.009">https://doi.org/10.1016/j.cell.2009.03.009</a>.'
  ieee: 'D. Weijers and J. Friml, “SnapShot: Auxin signaling and transport,” <i>Cell</i>,
    vol. 136, no. 6. Cell Press, pp. 1172–1172, 2009.'
  ista: 'Weijers D, Friml J. 2009. SnapShot: Auxin signaling and transport. Cell.
    136(6), 1172–1172.'
  mla: 'Weijers, Dolf, and Jiří Friml. “SnapShot: Auxin Signaling and Transport.”
    <i>Cell</i>, vol. 136, no. 6, Cell Press, 2009, pp. 1172–1172, doi:<a href="https://doi.org/10.1016/j.cell.2009.03.009">10.1016/j.cell.2009.03.009</a>.'
  short: D. Weijers, J. Friml, Cell 136 (2009) 1172–1172.
date_created: 2018-12-11T12:01:05Z
date_published: 2009-03-20T00:00:00Z
date_updated: 2021-01-12T07:40:42Z
day: '20'
doi: 10.1016/j.cell.2009.03.009
extern: '1'
external_id:
  pmid:
  - '    19303857'
intvolume: '       136'
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pubmed/19303857
month: '03'
oa: 1
oa_version: Published Version
page: 1172 - 1172
pmid: 1
publication: Cell
publication_status: published
publisher: Cell Press
publist_id: '3650'
quality_controlled: '1'
status: public
title: 'SnapShot: Auxin signaling and transport'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 136
year: '2009'
...
---
_id: '3052'
abstract:
- lang: eng
  text: The dynamic, differential distribution of the hormone auxin within plant tissues
    controls an impressive variety of developmental processes, which tailor plant
    growth and morphology to environmental conditions. Various environmental and endogenous
    signals can be integrated into changes in auxin distribution through their effects
    on local auxin biosynthesis and intercellular auxin transport. Individual cells
    interpret auxin largely by a nuclear signaling pathway that involves the F box
    protein TIR1 acting as an auxin receptor. Auxin-dependent TIR1 activity leads
    to ubiquitination-based degradation of transcriptional repressors and complex
    transcriptional reprogramming. Thus, auxin appears to be a versatile trigger of
    preprogrammed developmental changes in plant cells.
author:
- first_name: Steffen
  full_name: Vanneste, Steffen
  last_name: Vanneste
- first_name: Jirí
  full_name: Friml, Jirí
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: 'Vanneste S, Friml J. Auxin: A trigger for change in plant development. <i>Cell</i>.
    2009;136(6):1005-1016. doi:<a href="https://doi.org/10.1016/j.cell.2009.03.001">10.1016/j.cell.2009.03.001</a>'
  apa: 'Vanneste, S., &#38; Friml, J. (2009). Auxin: A trigger for change in plant
    development. <i>Cell</i>. Cell Press. <a href="https://doi.org/10.1016/j.cell.2009.03.001">https://doi.org/10.1016/j.cell.2009.03.001</a>'
  chicago: 'Vanneste, Steffen, and Jiří Friml. “Auxin: A Trigger for Change in Plant
    Development.” <i>Cell</i>. Cell Press, 2009. <a href="https://doi.org/10.1016/j.cell.2009.03.001">https://doi.org/10.1016/j.cell.2009.03.001</a>.'
  ieee: 'S. Vanneste and J. Friml, “Auxin: A trigger for change in plant development,”
    <i>Cell</i>, vol. 136, no. 6. Cell Press, pp. 1005–1016, 2009.'
  ista: 'Vanneste S, Friml J. 2009. Auxin: A trigger for change in plant development.
    Cell. 136(6), 1005–1016.'
  mla: 'Vanneste, Steffen, and Jiří Friml. “Auxin: A Trigger for Change in Plant Development.”
    <i>Cell</i>, vol. 136, no. 6, Cell Press, 2009, pp. 1005–16, doi:<a href="https://doi.org/10.1016/j.cell.2009.03.001">10.1016/j.cell.2009.03.001</a>.'
  short: S. Vanneste, J. Friml, Cell 136 (2009) 1005–1016.
date_created: 2018-12-11T12:01:05Z
date_published: 2009-03-20T00:00:00Z
date_updated: 2021-01-12T07:40:43Z
day: '20'
doi: 10.1016/j.cell.2009.03.001
extern: '1'
external_id:
  pmid:
  - '    19303845'
intvolume: '       136'
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pubmed/19303845
month: '03'
oa: 1
oa_version: Published Version
page: 1005 - 1016
pmid: 1
publication: Cell
publication_status: published
publisher: Cell Press
publist_id: '3651'
quality_controlled: '1'
status: public
title: 'Auxin: A trigger for change in plant development'
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 136
year: '2009'
...
---
_id: '3053'
author:
- first_name: Eva
  full_name: Benková, Eva
  id: 38F4F166-F248-11E8-B48F-1D18A9856A87
  last_name: Benková
  orcid: 0000-0002-8510-9739
- first_name: Maria
  full_name: Ivanchenko, Maria
  last_name: Ivanchenko
- first_name: Jirí
  full_name: Friml, Jirí
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Svetlana
  full_name: Shishkova, Svetlana
  last_name: Shishkova
- first_name: Joseph
  full_name: Dubrovsky, Joseph
  last_name: Dubrovsky
citation:
  ama: 'Benková E, Ivanchenko M, Friml J, Shishkova S, Dubrovsky J. A morphogenetic
    trigger: Is there an emerging concept in plant developmental biology? <i>Trends
    in Plant Science</i>. 2009;14(4):189-193. doi:<a href="https://doi.org/10.1016/j.tplants.2009.01.006">10.1016/j.tplants.2009.01.006</a>'
  apa: 'Benková, E., Ivanchenko, M., Friml, J., Shishkova, S., &#38; Dubrovsky, J.
    (2009). A morphogenetic trigger: Is there an emerging concept in plant developmental
    biology? <i>Trends in Plant Science</i>. Cell Press. <a href="https://doi.org/10.1016/j.tplants.2009.01.006">https://doi.org/10.1016/j.tplants.2009.01.006</a>'
  chicago: 'Benková, Eva, Maria Ivanchenko, Jiří Friml, Svetlana Shishkova, and Joseph
    Dubrovsky. “A Morphogenetic Trigger: Is There an Emerging Concept in Plant Developmental
    Biology?” <i>Trends in Plant Science</i>. Cell Press, 2009. <a href="https://doi.org/10.1016/j.tplants.2009.01.006">https://doi.org/10.1016/j.tplants.2009.01.006</a>.'
  ieee: 'E. Benková, M. Ivanchenko, J. Friml, S. Shishkova, and J. Dubrovsky, “A morphogenetic
    trigger: Is there an emerging concept in plant developmental biology?,” <i>Trends
    in Plant Science</i>, vol. 14, no. 4. Cell Press, pp. 189–193, 2009.'
  ista: 'Benková E, Ivanchenko M, Friml J, Shishkova S, Dubrovsky J. 2009. A morphogenetic
    trigger: Is there an emerging concept in plant developmental biology? Trends in
    Plant Science. 14(4), 189–193.'
  mla: 'Benková, Eva, et al. “A Morphogenetic Trigger: Is There an Emerging Concept
    in Plant Developmental Biology?” <i>Trends in Plant Science</i>, vol. 14, no.
    4, Cell Press, 2009, pp. 189–93, doi:<a href="https://doi.org/10.1016/j.tplants.2009.01.006">10.1016/j.tplants.2009.01.006</a>.'
  short: E. Benková, M. Ivanchenko, J. Friml, S. Shishkova, J. Dubrovsky, Trends in
    Plant Science 14 (2009) 189–193.
date_created: 2018-12-11T12:01:05Z
date_published: 2009-04-01T00:00:00Z
date_updated: 2021-01-12T07:40:43Z
day: '01'
doi: 10.1016/j.tplants.2009.01.006
extern: '1'
intvolume: '        14'
issue: '4'
language:
- iso: eng
month: '04'
oa_version: None
page: 189 - 193
publication: Trends in Plant Science
publication_status: published
publisher: Cell Press
publist_id: '3649'
status: public
title: 'A morphogenetic trigger: Is there an emerging concept in plant developmental
  biology?'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 14
year: '2009'
...
---
_id: '3054'
abstract:
- lang: eng
  text: As multicellular organisms, plants, like animals, use endogenous signaling
    molecules to coordinate their own physiology and development. To compensate for
    the absence of a cardiovascular system, plants have evolved specialized transport
    pathways to distribute signals and nutrients. The main transport streams include
    the xylem flow of the nutrients from the root to the shoot and the phloem flow
    of materials from the photosynthetic active tissues. These long-distance transport
    processes are complemented by several intercellular transport mechanisms (apoplastic,
    symplastic and transcellular transport). A prominent example of transcellular
    flow is transport of the phytohormone auxin within tissues. The process is mediated
    by influx and efflux carriers, whose polar localization in the plasma membrane
    determines the directionality of the flow. This polar auxin transport generates
    auxin maxima and gradients within tissues that are instrumental in the diverse
    regulation of various plant developmental processes, including embryogenesis,
    organogenesis, vascular tissue formation and tropisms.
author:
- first_name: Hélène
  full_name: Robert, Hélène
  last_name: Robert
- first_name: Jirí
  full_name: Friml, Jirí
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: Robert H, Friml J. Auxin and other signals on the move in plants. <i>Nature
    Chemical Biology</i>. 2009;5(5):325-332. doi:<a href="https://doi.org/10.1038/nchembio.170">10.1038/nchembio.170</a>
  apa: Robert, H., &#38; Friml, J. (2009). Auxin and other signals on the move in
    plants. <i>Nature Chemical Biology</i>. Nature Publishing Group. <a href="https://doi.org/10.1038/nchembio.170">https://doi.org/10.1038/nchembio.170</a>
  chicago: Robert, Hélène, and Jiří Friml. “Auxin and Other Signals on the Move in
    Plants.” <i>Nature Chemical Biology</i>. Nature Publishing Group, 2009. <a href="https://doi.org/10.1038/nchembio.170">https://doi.org/10.1038/nchembio.170</a>.
  ieee: H. Robert and J. Friml, “Auxin and other signals on the move in plants,” <i>Nature
    Chemical Biology</i>, vol. 5, no. 5. Nature Publishing Group, pp. 325–332, 2009.
  ista: Robert H, Friml J. 2009. Auxin and other signals on the move in plants. Nature
    Chemical Biology. 5(5), 325–332.
  mla: Robert, Hélène, and Jiří Friml. “Auxin and Other Signals on the Move in Plants.”
    <i>Nature Chemical Biology</i>, vol. 5, no. 5, Nature Publishing Group, 2009,
    pp. 325–32, doi:<a href="https://doi.org/10.1038/nchembio.170">10.1038/nchembio.170</a>.
  short: H. Robert, J. Friml, Nature Chemical Biology 5 (2009) 325–332.
date_created: 2018-12-11T12:01:06Z
date_published: 2009-05-01T00:00:00Z
date_updated: 2021-01-12T07:40:43Z
day: '01'
doi: 10.1038/nchembio.170
extern: '1'
external_id:
  pmid:
  - '    19377459'
intvolume: '         5'
issue: '5'
language:
- iso: eng
month: '05'
oa_version: None
page: 325 - 332
pmid: 1
publication: Nature Chemical Biology
publication_status: published
publisher: Nature Publishing Group
publist_id: '3648'
quality_controlled: '1'
status: public
title: Auxin and other signals on the move in plants
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2009'
...
---
_id: '3055'
abstract:
- lang: eng
  text: 'ACAP-type ARF GTPase activating proteins (ARF-GAPs) regulate multiple cellular
    processes, including endocytosis, secretion, phagocytosis, cell adhesion and cell
    migration. However, the regulation of ACAP functions by other cellular proteins
    is poorly understood. We have reported previously that a plant ACAP, VAN3, plays
    a pivotal role in plant venation continuity. Here, we report on newly identified
    VAN3 regulators: the CVP2 (cotyledon vascular pattern 2) 5 PTase, which is considered
    to degrade IP3 and also to produce PtdIns(4)P from PtdIns(4,5)P2; and a PH domain-containing
    protein, VAB (VAN3 binding protein). Combinational mutations of both CVP2 and
    its closest homologue CVL1 (CVP2 like 1) phenocopied the strong allele of van3
    mutants, showing severe vascular continuity. The phenotype of double mutants between
    van3, cvp2 and vab suggested that VAN3, CVP2 and VAB function in vascular pattern
    formation in the same pathway. Localization analysis revealed that both CVP2 and
    VAB colocalize with VAN3 in the trans- Golgi network (TGN), supporting their functions
    in the same pathway. The subcellular localization of VAN3 was dependent on its
    PH domain, and mislocalization of VAN3 was induced in cvp2 or vab mutants. These
    results suggest that CVP2 and VAB cooperatively regulate the subcellular localization
    of VAN3 through the interaction between its PH domain and phosphoinositides and/or
    inositol phosphates. In addition, PtdIns(4)P, to which VAN3 binds preferentially,
    enhanced the ARF-GAP activity of VAN3, whereas IP3 inhibited it. These results
    suggest the existence of PtdIns(4)P and/or IP3-dependent subcellular targeting
    and regulation of VAN3 ACAP activity that governs plant vascular tissue continuity.'
author:
- first_name: Satoshi
  full_name: Naramoto, Satoshi
  last_name: Naramoto
- first_name: Shinichiro
  full_name: Sawa, Shinichiro
  last_name: Sawa
- first_name: Koji
  full_name: Koizumi, Koji
  last_name: Koizumi
- first_name: Tomohiro
  full_name: Uemura, Tomohiro
  last_name: Uemura
- first_name: Takashi
  full_name: Ueda, Takashi
  last_name: Ueda
- first_name: Jirí
  full_name: Jirí Friml
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Akihiko
  full_name: Nakano, Akihiko
  last_name: Nakano
- first_name: Hiroo
  full_name: Fukuda, Hiroo
  last_name: Fukuda
citation:
  ama: Naramoto S, Sawa S, Koizumi K, et al. Phosphoinositide-dependent regulation
    of VAN3 ARF-GAP localization and activity essential for vascular tissue continuity
    in plants. <i>Development</i>. 2009;136(9):1529-1538. doi:<a href="https://doi.org/10.1242/dev.030098">10.1242/dev.030098</a>
  apa: Naramoto, S., Sawa, S., Koizumi, K., Uemura, T., Ueda, T., Friml, J., … Fukuda,
    H. (2009). Phosphoinositide-dependent regulation of VAN3 ARF-GAP localization
    and activity essential for vascular tissue continuity in plants. <i>Development</i>.
    Company of Biologists. <a href="https://doi.org/10.1242/dev.030098">https://doi.org/10.1242/dev.030098</a>
  chicago: Naramoto, Satoshi, Shinichiro Sawa, Koji Koizumi, Tomohiro Uemura, Takashi
    Ueda, Jiří Friml, Akihiko Nakano, and Hiroo Fukuda. “Phosphoinositide-Dependent
    Regulation of VAN3 ARF-GAP Localization and Activity Essential for Vascular Tissue
    Continuity in Plants.” <i>Development</i>. Company of Biologists, 2009. <a href="https://doi.org/10.1242/dev.030098">https://doi.org/10.1242/dev.030098</a>.
  ieee: S. Naramoto <i>et al.</i>, “Phosphoinositide-dependent regulation of VAN3
    ARF-GAP localization and activity essential for vascular tissue continuity in
    plants,” <i>Development</i>, vol. 136, no. 9. Company of Biologists, pp. 1529–1538,
    2009.
  ista: Naramoto S, Sawa S, Koizumi K, Uemura T, Ueda T, Friml J, Nakano A, Fukuda
    H. 2009. Phosphoinositide-dependent regulation of VAN3 ARF-GAP localization and
    activity essential for vascular tissue continuity in plants. Development. 136(9),
    1529–1538.
  mla: Naramoto, Satoshi, et al. “Phosphoinositide-Dependent Regulation of VAN3 ARF-GAP
    Localization and Activity Essential for Vascular Tissue Continuity in Plants.”
    <i>Development</i>, vol. 136, no. 9, Company of Biologists, 2009, pp. 1529–38,
    doi:<a href="https://doi.org/10.1242/dev.030098">10.1242/dev.030098</a>.
  short: S. Naramoto, S. Sawa, K. Koizumi, T. Uemura, T. Ueda, J. Friml, A. Nakano,
    H. Fukuda, Development 136 (2009) 1529–1538.
date_created: 2018-12-11T12:01:06Z
date_published: 2009-05-01T00:00:00Z
date_updated: 2021-01-12T07:40:44Z
day: '01'
doi: 10.1242/dev.030098
extern: 1
intvolume: '       136'
issue: '9'
month: '05'
page: 1529 - 1538
publication: Development
publication_status: published
publisher: Company of Biologists
publist_id: '3647'
quality_controlled: 0
status: public
title: Phosphoinositide-dependent regulation of VAN3 ARF-GAP localization and activity
  essential for vascular tissue continuity in plants
type: journal_article
volume: 136
year: '2009'
...
---
_id: '3056'
abstract:
- lang: eng
  text: Local hormone maxima are essential for the development of multicellular structures
    and organs. For example, steroid hormones accumulate in specific cell types of
    the animal fetus to induce sexual differentiation and concentration peaks of the
    plant hormone auxin direct organ initiation and mediate tissue patterning. Here
    we provide an example of a regulated local hormone minimum required during organogenesis.
    Our results demonstrate that formation of a local auxin minimum is necessary for
    specification of the valve margin separation layer where Arabidopsis fruit opening
    takes place. Consequently, ectopic production of auxin, specifically in valve
    margin cells, leads to a complete loss of proper cell fate determination. The
    valve margin identity factor INDEHISCENT (IND) is responsible for forming the
    auxin minimum by coordinating auxin efflux in separation-layer cells. We propose
    that the simplicity of formation and maintenance make local hormone minima particularly
    well suited to specify a small number of cells such as the stripes at the valve
    margins.
author:
- first_name: Karim
  full_name: Sorefan, Karim
  last_name: Sorefan
- first_name: Thomas
  full_name: Girin, Thomas
  last_name: Girin
- first_name: Sarah
  full_name: Liljegren, Sarah J
  last_name: Liljegren
- first_name: Karin
  full_name: Ljung, Karin
  last_name: Ljung
- first_name: Pedro
  full_name: Robles, Pedro
  last_name: Robles
- first_name: Carlos
  full_name: Galván-Ampudia, Carlos S
  last_name: Galván Ampudia
- first_name: Remko
  full_name: Offringa, Remko
  last_name: Offringa
- first_name: Jirí
  full_name: Jirí Friml
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Martin
  full_name: Yanofsky, Martin F
  last_name: Yanofsky
- first_name: Lars
  full_name: Østergaard, Lars
  last_name: Østergaard
citation:
  ama: Sorefan K, Girin T, Liljegren S, et al. A regulated auxin minimum is required
    for seed dispersal in Arabidopsis. <i>Nature</i>. 2009;459(7246):583-586. doi:<a
    href="https://doi.org/10.1038/nature07875">10.1038/nature07875</a>
  apa: Sorefan, K., Girin, T., Liljegren, S., Ljung, K., Robles, P., Galván Ampudia,
    C., … Østergaard, L. (2009). A regulated auxin minimum is required for seed dispersal
    in Arabidopsis. <i>Nature</i>. Nature Publishing Group. <a href="https://doi.org/10.1038/nature07875">https://doi.org/10.1038/nature07875</a>
  chicago: Sorefan, Karim, Thomas Girin, Sarah Liljegren, Karin Ljung, Pedro Robles,
    Carlos Galván Ampudia, Remko Offringa, Jiří Friml, Martin Yanofsky, and Lars Østergaard.
    “A Regulated Auxin Minimum Is Required for Seed Dispersal in Arabidopsis.” <i>Nature</i>.
    Nature Publishing Group, 2009. <a href="https://doi.org/10.1038/nature07875">https://doi.org/10.1038/nature07875</a>.
  ieee: K. Sorefan <i>et al.</i>, “A regulated auxin minimum is required for seed
    dispersal in Arabidopsis,” <i>Nature</i>, vol. 459, no. 7246. Nature Publishing
    Group, pp. 583–586, 2009.
  ista: Sorefan K, Girin T, Liljegren S, Ljung K, Robles P, Galván Ampudia C, Offringa
    R, Friml J, Yanofsky M, Østergaard L. 2009. A regulated auxin minimum is required
    for seed dispersal in Arabidopsis. Nature. 459(7246), 583–586.
  mla: Sorefan, Karim, et al. “A Regulated Auxin Minimum Is Required for Seed Dispersal
    in Arabidopsis.” <i>Nature</i>, vol. 459, no. 7246, Nature Publishing Group, 2009,
    pp. 583–86, doi:<a href="https://doi.org/10.1038/nature07875">10.1038/nature07875</a>.
  short: K. Sorefan, T. Girin, S. Liljegren, K. Ljung, P. Robles, C. Galván Ampudia,
    R. Offringa, J. Friml, M. Yanofsky, L. Østergaard, Nature 459 (2009) 583–586.
date_created: 2018-12-11T12:01:06Z
date_published: 2009-05-28T00:00:00Z
date_updated: 2021-01-12T07:40:44Z
day: '28'
doi: 10.1038/nature07875
extern: 1
intvolume: '       459'
issue: '7246'
month: '05'
page: 583 - 586
publication: Nature
publication_status: published
publisher: Nature Publishing Group
publist_id: '3646'
quality_controlled: 0
status: public
title: A regulated auxin minimum is required for seed dispersal in Arabidopsis
type: journal_article
volume: 459
year: '2009'
...
---
_id: '3057'
abstract:
- lang: eng
  text: The differential distribution of the plant signaling molecule auxin is required
    for many aspects of plant development. Local auxin maxima and gradients arise
    as a result of local auxin metabolism and, predominantly, from directional cell-to-cell
    transport. In this primer, we discuss how the coordinated activity of several
    auxin influx and efflux systems, which transport auxin across the plasma membrane,
    mediates directional auxin flow. This activity crucially contributes to the correct
    setting of developmental cues in embryogenesis, organogenesis, vascular tissue
    formation and directional growth in response to environmental stimuli.
author:
- first_name: Jan
  full_name: Petrášek, Jan
  last_name: Petrášek
- first_name: Jirí
  full_name: Friml, Jirí
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: Petrášek J, Friml J. Auxin transport routes in plant development. <i>Development</i>.
    2009;136(16):2675-2688. doi:<a href="https://doi.org/10.1242/dev.030353">10.1242/dev.030353</a>
  apa: Petrášek, J., &#38; Friml, J. (2009). Auxin transport routes in plant development.
    <i>Development</i>. Company of Biologists. <a href="https://doi.org/10.1242/dev.030353">https://doi.org/10.1242/dev.030353</a>
  chicago: Petrášek, Jan, and Jiří Friml. “Auxin Transport Routes in Plant Development.”
    <i>Development</i>. Company of Biologists, 2009. <a href="https://doi.org/10.1242/dev.030353">https://doi.org/10.1242/dev.030353</a>.
  ieee: J. Petrášek and J. Friml, “Auxin transport routes in plant development,” <i>Development</i>,
    vol. 136, no. 16. Company of Biologists, pp. 2675–2688, 2009.
  ista: Petrášek J, Friml J. 2009. Auxin transport routes in plant development. Development.
    136(16), 2675–2688.
  mla: Petrášek, Jan, and Jiří Friml. “Auxin Transport Routes in Plant Development.”
    <i>Development</i>, vol. 136, no. 16, Company of Biologists, 2009, pp. 2675–88,
    doi:<a href="https://doi.org/10.1242/dev.030353">10.1242/dev.030353</a>.
  short: J. Petrášek, J. Friml, Development 136 (2009) 2675–2688.
date_created: 2018-12-11T12:01:07Z
date_published: 2009-08-15T00:00:00Z
date_updated: 2021-01-12T07:40:45Z
day: '15'
doi: 10.1242/dev.030353
extern: '1'
external_id:
  pmid:
  - '    19633168'
intvolume: '       136'
issue: '16'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pubmed/19633168
month: '08'
oa: 1
oa_version: Published Version
page: 2675 - 2688
pmid: 1
publication: Development
publication_status: published
publisher: Company of Biologists
publist_id: '3644'
quality_controlled: '1'
status: public
title: Auxin transport routes in plant development
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 136
year: '2009'
...
---
_id: '3058'
abstract:
- lang: eng
  text: The plant signalling molecule auxin provides positional informa-tion in a
    variety of developmental processes by means of its differential distribution (gradients)
    within plant tissues. Thus, cellular auxin levels often determine the developmental
    output of auxin signalling. Conceptually, transmembrane transport and metabolic
    processes regulate the steady-state levels of auxin in any given cell2,3. In particular,
    PIN auxin-efflux-carrier-mediated, directional transport between cells is crucial
    for generating auxin gradients2,4,5. Here we show that Arabidopsis thaliana PIN5,
    an atypical member of the PIN gene family, encodes a functional auxin transporter
    that is required for auxin-mediated develop-ment. PIN5 does not have a direct
    role in cell-to-cell transport but regulates intracellular auxin homeostasis and
    metabolism. PIN5 localizes, unlike other characterized plasma membrane PIN proteins,
    to endoplasmic reticulum (ER), presumably medi-ating auxin flow from the cytosol
    to the lumen of the ER. The ER localization of other PIN5-like transporters (including
    the moss PIN) indicates that the diversification of PIN protein functions in mediating
    auxin homeostasis at the ER, and cell-to-cell auxin transport at the plasma membrane,
    represent an ancient event during the evolution of land plants.
author:
- first_name: Jozef
  full_name: Mravec, Jozef
  last_name: Mravec
- first_name: Petr
  full_name: Skůpa, Petr
  last_name: Skůpa
- first_name: Aurélien
  full_name: Bailly, Aurélien
  last_name: Bailly
- first_name: Klára
  full_name: Hoyerová, Klára
  last_name: Hoyerová
- first_name: Pavel
  full_name: Křeček, Pavel
  last_name: Křeček
- first_name: Agnieszka
  full_name: Bielach, Agnieszka
  last_name: Bielach
- first_name: Jan
  full_name: Petrášek, Jan
  last_name: Petrášek
- first_name: Jing
  full_name: Zhang, Jing
  last_name: Zhang
- first_name: Vassilena
  full_name: Gaykova, Vassilena
  last_name: Gaykova
- first_name: York
  full_name: Stierhof, York-Dieter
  last_name: Stierhof
- first_name: Petre
  full_name: Dobrev, Petre I
  last_name: Dobrev
- first_name: Kateřina
  full_name: Schwarzerová, Kateřina
  last_name: Schwarzerová
- first_name: Jakub
  full_name: Rolčík, Jakub
  last_name: Rolčík
- first_name: Daniela
  full_name: Seifertová, Daniela
  last_name: Seifertová
- first_name: Christian
  full_name: Luschnig, Christian
  last_name: Luschnig
- first_name: Eva
  full_name: Eva Benková
  id: 38F4F166-F248-11E8-B48F-1D18A9856A87
  last_name: Benková
  orcid: 0000-0002-8510-9739
- first_name: Eva
  full_name: Zažímalová, Eva
  last_name: Zažímalová
- first_name: Markus
  full_name: Geisler, Markus
  last_name: Geisler
- first_name: Jirí
  full_name: Jirí Friml
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: Mravec J, Skůpa P, Bailly A, et al. Subcellular homeostasis of phytohormone
    auxin is mediated by the ER localized PIN5 transporter. <i>Nature</i>. 2009;459(7250):1136-1140.
    doi:<a href="https://doi.org/10.1038/nature08066">10.1038/nature08066</a>
  apa: Mravec, J., Skůpa, P., Bailly, A., Hoyerová, K., Křeček, P., Bielach, A., …
    Friml, J. (2009). Subcellular homeostasis of phytohormone auxin is mediated by
    the ER localized PIN5 transporter. <i>Nature</i>. Nature Publishing Group. <a
    href="https://doi.org/10.1038/nature08066">https://doi.org/10.1038/nature08066</a>
  chicago: Mravec, Jozef, Petr Skůpa, Aurélien Bailly, Klára Hoyerová, Pavel Křeček,
    Agnieszka Bielach, Jan Petrášek, et al. “Subcellular Homeostasis of Phytohormone
    Auxin Is Mediated by the ER Localized PIN5 Transporter.” <i>Nature</i>. Nature
    Publishing Group, 2009. <a href="https://doi.org/10.1038/nature08066">https://doi.org/10.1038/nature08066</a>.
  ieee: J. Mravec <i>et al.</i>, “Subcellular homeostasis of phytohormone auxin is
    mediated by the ER localized PIN5 transporter,” <i>Nature</i>, vol. 459, no. 7250.
    Nature Publishing Group, pp. 1136–1140, 2009.
  ista: Mravec J, Skůpa P, Bailly A, Hoyerová K, Křeček P, Bielach A, Petrášek J,
    Zhang J, Gaykova V, Stierhof Y, Dobrev P, Schwarzerová K, Rolčík J, Seifertová
    D, Luschnig C, Benková E, Zažímalová E, Geisler M, Friml J. 2009. Subcellular
    homeostasis of phytohormone auxin is mediated by the ER localized PIN5 transporter.
    Nature. 459(7250), 1136–1140.
  mla: Mravec, Jozef, et al. “Subcellular Homeostasis of Phytohormone Auxin Is Mediated
    by the ER Localized PIN5 Transporter.” <i>Nature</i>, vol. 459, no. 7250, Nature
    Publishing Group, 2009, pp. 1136–40, doi:<a href="https://doi.org/10.1038/nature08066">10.1038/nature08066</a>.
  short: J. Mravec, P. Skůpa, A. Bailly, K. Hoyerová, P. Křeček, A. Bielach, J. Petrášek,
    J. Zhang, V. Gaykova, Y. Stierhof, P. Dobrev, K. Schwarzerová, J. Rolčík, D. Seifertová,
    C. Luschnig, E. Benková, E. Zažímalová, M. Geisler, J. Friml, Nature 459 (2009)
    1136–1140.
date_created: 2018-12-11T12:01:07Z
date_published: 2009-06-25T00:00:00Z
date_updated: 2021-01-12T07:40:45Z
day: '25'
doi: 10.1038/nature08066
extern: 1
intvolume: '       459'
issue: '7250'
month: '06'
page: 1136 - 1140
publication: Nature
publication_status: published
publisher: Nature Publishing Group
publist_id: '3645'
quality_controlled: 0
status: public
title: Subcellular homeostasis of phytohormone auxin is mediated by the ER localized
  PIN5 transporter
type: journal_article
volume: 459
year: '2009'
...
---
_id: '3059'
abstract:
- lang: eng
  text: The phytohormone auxin plays a major role in embryonic and postembryonic plant
    development. The temporal and spatial distribution of auxin largely depends on
    the subcellular polar localization of members of the PIN-FORMED (PIN) auxin efflux
    carrier family. The Ser/Thr protein kinase PINOID (PID) catalyzes PIN phosphorylation
    and crucially contributes to the regulation of apical-basal PIN polarity. The
    GTP exchange factor on ADP-ribosylation factors (ARF-GEF), GNOM preferentially
    mediates PIN recycling at the basal side of the cell. Interference with GNOM activity
    leads to dynamic PIN transcytosis between different sides of the cell. Our genetic,
    pharmacological, and cell biological approaches illustrate that PID and GNOM influence
    PIN polarity and plant development in an antagonistic manner and that the PID-dependent
    PIN phosphorylation results in GNOM-independent polar PIN targeting. The data
    suggest that PID and the protein phosphatase 2A not only regulate the static PIN
    polarity, but also act antagonistically on the rate of GNOM-dependent polar PIN
    transcytosis. We propose a model that includes PID-dependent PIN phosphorylation
    at the plasma membrane and the subsequent sorting of PIN proteins to a GNOM-independent
    pathway for polarity alterations during developmental processes, such as lateral
    root formation and leaf vasculature development.
author:
- first_name: Jürgen
  full_name: Kleine-Vehn, Jürgen
  last_name: Kleine Vehn
- first_name: Fang
  full_name: Huang, Fang
  last_name: Huang
- first_name: Satoshi
  full_name: Naramoto, Satoshi
  last_name: Naramoto
- first_name: Jing
  full_name: Zhang, Jing
  last_name: Zhang
- first_name: Marta
  full_name: Michniewicz, Marta
  last_name: Michniewicz
- first_name: Remko
  full_name: Offringa, Remko
  last_name: Offringa
- first_name: Jirí
  full_name: Jirí Friml
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: Kleine Vehn J, Huang F, Naramoto S, et al. PIN auxin efflux carrier polarity
    is regulated by PINOID kinase mediated recruitment into GNOM independent trafficking
    in arabidopsis. <i>Plant Cell</i>. 2009;21(12):3839-3849. doi:<a href="https://doi.org/10.1105/tpc.109.071639">10.1105/tpc.109.071639</a>
  apa: Kleine Vehn, J., Huang, F., Naramoto, S., Zhang, J., Michniewicz, M., Offringa,
    R., &#38; Friml, J. (2009). PIN auxin efflux carrier polarity is regulated by
    PINOID kinase mediated recruitment into GNOM independent trafficking in arabidopsis.
    <i>Plant Cell</i>. American Society of Plant Biologists. <a href="https://doi.org/10.1105/tpc.109.071639">https://doi.org/10.1105/tpc.109.071639</a>
  chicago: Kleine Vehn, Jürgen, Fang Huang, Satoshi Naramoto, Jing Zhang, Marta Michniewicz,
    Remko Offringa, and Jiří Friml. “PIN Auxin Efflux Carrier Polarity Is Regulated
    by PINOID Kinase Mediated Recruitment into GNOM Independent Trafficking in Arabidopsis.”
    <i>Plant Cell</i>. American Society of Plant Biologists, 2009. <a href="https://doi.org/10.1105/tpc.109.071639">https://doi.org/10.1105/tpc.109.071639</a>.
  ieee: J. Kleine Vehn <i>et al.</i>, “PIN auxin efflux carrier polarity is regulated
    by PINOID kinase mediated recruitment into GNOM independent trafficking in arabidopsis,”
    <i>Plant Cell</i>, vol. 21, no. 12. American Society of Plant Biologists, pp.
    3839–3849, 2009.
  ista: Kleine Vehn J, Huang F, Naramoto S, Zhang J, Michniewicz M, Offringa R, Friml
    J. 2009. PIN auxin efflux carrier polarity is regulated by PINOID kinase mediated
    recruitment into GNOM independent trafficking in arabidopsis. Plant Cell. 21(12),
    3839–3849.
  mla: Kleine Vehn, Jürgen, et al. “PIN Auxin Efflux Carrier Polarity Is Regulated
    by PINOID Kinase Mediated Recruitment into GNOM Independent Trafficking in Arabidopsis.”
    <i>Plant Cell</i>, vol. 21, no. 12, American Society of Plant Biologists, 2009,
    pp. 3839–49, doi:<a href="https://doi.org/10.1105/tpc.109.071639">10.1105/tpc.109.071639</a>.
  short: J. Kleine Vehn, F. Huang, S. Naramoto, J. Zhang, M. Michniewicz, R. Offringa,
    J. Friml, Plant Cell 21 (2009) 3839–3849.
date_created: 2018-12-11T12:01:07Z
date_published: 2009-12-01T00:00:00Z
date_updated: 2021-01-12T07:40:45Z
day: '01'
doi: 10.1105/tpc.109.071639
extern: 1
intvolume: '        21'
issue: '12'
month: '12'
page: 3839 - 3849
publication: Plant Cell
publication_status: published
publisher: American Society of Plant Biologists
publist_id: '3643'
quality_controlled: 0
status: public
title: PIN auxin efflux carrier polarity is regulated by PINOID kinase mediated recruitment
  into GNOM independent trafficking in arabidopsis
type: journal_article
volume: 21
year: '2009'
...
---
_id: '3060'
article_type: letter_note
author:
- first_name: Karin
  full_name: Schumacher, Karin
  last_name: Schumacher
- first_name: Jirí
  full_name: Friml, Jirí
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: Schumacher K, Friml J. Cell biology. <i>Current Opinion in Plant Biology</i>.
    2009;12(6):651-652. doi:<a href="https://doi.org/10.1016/j.pbi.2009.10.009">10.1016/j.pbi.2009.10.009</a>
  apa: Schumacher, K., &#38; Friml, J. (2009). Cell biology. <i>Current Opinion in
    Plant Biology</i>. Elsevier. <a href="https://doi.org/10.1016/j.pbi.2009.10.009">https://doi.org/10.1016/j.pbi.2009.10.009</a>
  chicago: Schumacher, Karin, and Jiří Friml. “Cell Biology.” <i>Current Opinion in
    Plant Biology</i>. Elsevier, 2009. <a href="https://doi.org/10.1016/j.pbi.2009.10.009">https://doi.org/10.1016/j.pbi.2009.10.009</a>.
  ieee: K. Schumacher and J. Friml, “Cell biology,” <i>Current Opinion in Plant Biology</i>,
    vol. 12, no. 6. Elsevier, pp. 651–652, 2009.
  ista: Schumacher K, Friml J. 2009. Cell biology. Current Opinion in Plant Biology.
    12(6), 651–652.
  mla: Schumacher, Karin, and Jiří Friml. “Cell Biology.” <i>Current Opinion in Plant
    Biology</i>, vol. 12, no. 6, Elsevier, 2009, pp. 651–52, doi:<a href="https://doi.org/10.1016/j.pbi.2009.10.009">10.1016/j.pbi.2009.10.009</a>.
  short: K. Schumacher, J. Friml, Current Opinion in Plant Biology 12 (2009) 651–652.
date_created: 2018-12-11T12:01:08Z
date_published: 2009-12-01T00:00:00Z
date_updated: 2021-01-12T07:40:46Z
day: '01'
doi: 10.1016/j.pbi.2009.10.009
extern: '1'
intvolume: '        12'
issue: '6'
language:
- iso: eng
month: '12'
oa_version: None
page: 651 - 652
publication: Current Opinion in Plant Biology
publication_status: published
publisher: Elsevier
publist_id: '3641'
quality_controlled: '1'
status: public
title: Cell biology
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 12
year: '2009'
...
---
_id: '3061'
abstract:
- lang: eng
  text: The PIN-FORMED (PIN) proteins are secondary transporters acting in the efflux
    of the plant signal molecule auxin from cells. They are asymmetrically localized
    within cells and their polarity determines the directionality of intercellular
    auxin flow. PIN genes are found exclusively in the genomes of multicellular plants
    and play an important role in regulating asymmetric auxin distribution in multiple
    developmental processes, including embryogenesis, organogenesis, tissue differentiation
    and tropic responses. All PIN proteins have a similar structure with amino- and
    carboxy-terminal hydrophobic, membrane-spanning domains separated by a central
    hydrophilic domain. The structure of the hydrophobic domains is well conserved.
    The hydrophilic domain is more divergent and it determines eight groups within
    the protein family. The activity of PIN proteins is regulated at multiple levels,
    including transcription, protein stability, subcellular localization and transport
    activity. Different endogenous and environmental signals can modulate PIN activity
    and thus modulate auxin-distribution-dependent development. A large group of PIN
    proteins, including the most ancient members known from mosses, localize to the
    endoplasmic reticulum and they regulate the subcellular compartmentalization of
    auxin and thus auxin metabolism. Further work is needed to establish the physiological
    importance of this unexpected mode of auxin homeostasis regulation. Furthermore,
    the evolution of PIN-based transport, PIN protein structure and more detailed
    biochemical characterization of the transport function are important topics for
    further studies.
author:
- first_name: Pavel
  full_name: Křeček, Pavel
  last_name: Křeček
- first_name: Petr
  full_name: Skůpa, Petr
  last_name: Skůpa
- first_name: Jiří
  full_name: Libus, Jiří
  last_name: Libus
- first_name: Satoshi
  full_name: Naramoto, Satoshi
  last_name: Naramoto
- first_name: Ricardo
  full_name: Tejos, Ricardo
  last_name: Tejos
- first_name: Jirí
  full_name: Friml, Jirí
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Eva
  full_name: Zažímalová, Eva
  last_name: Zažímalová
citation:
  ama: Křeček P, Skůpa P, Libus J, et al. The PIN-FORMED (PIN) protein family of auxin
    transporters. <i>Genome Biology</i>. 2009;10(12). doi:<a href="https://doi.org/10.1186/gb-2009-10-12-249">10.1186/gb-2009-10-12-249</a>
  apa: Křeček, P., Skůpa, P., Libus, J., Naramoto, S., Tejos, R., Friml, J., &#38;
    Zažímalová, E. (2009). The PIN-FORMED (PIN) protein family of auxin transporters.
    <i>Genome Biology</i>. BioMed Central. <a href="https://doi.org/10.1186/gb-2009-10-12-249">https://doi.org/10.1186/gb-2009-10-12-249</a>
  chicago: Křeček, Pavel, Petr Skůpa, Jiří Libus, Satoshi Naramoto, Ricardo Tejos,
    Jiří Friml, and Eva Zažímalová. “The PIN-FORMED (PIN) Protein Family of Auxin
    Transporters.” <i>Genome Biology</i>. BioMed Central, 2009. <a href="https://doi.org/10.1186/gb-2009-10-12-249">https://doi.org/10.1186/gb-2009-10-12-249</a>.
  ieee: P. Křeček <i>et al.</i>, “The PIN-FORMED (PIN) protein family of auxin transporters,”
    <i>Genome Biology</i>, vol. 10, no. 12. BioMed Central, 2009.
  ista: Křeček P, Skůpa P, Libus J, Naramoto S, Tejos R, Friml J, Zažímalová E. 2009.
    The PIN-FORMED (PIN) protein family of auxin transporters. Genome Biology. 10(12).
  mla: Křeček, Pavel, et al. “The PIN-FORMED (PIN) Protein Family of Auxin Transporters.”
    <i>Genome Biology</i>, vol. 10, no. 12, BioMed Central, 2009, doi:<a href="https://doi.org/10.1186/gb-2009-10-12-249">10.1186/gb-2009-10-12-249</a>.
  short: P. Křeček, P. Skůpa, J. Libus, S. Naramoto, R. Tejos, J. Friml, E. Zažímalová,
    Genome Biology 10 (2009).
date_created: 2018-12-11T12:01:08Z
date_published: 2009-12-29T00:00:00Z
date_updated: 2021-01-12T07:40:46Z
day: '29'
doi: 10.1186/gb-2009-10-12-249
extern: '1'
external_id:
  pmid:
  - '20053306'
intvolume: '        10'
issue: '12'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812941/
month: '12'
oa: 1
oa_version: Published Version
pmid: 1
publication: Genome Biology
publication_status: published
publisher: BioMed Central
publist_id: '3640'
quality_controlled: '1'
status: public
title: The PIN-FORMED (PIN) protein family of auxin transporters
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 10
year: '2009'
...
---
_id: '3197'
abstract:
- lang: eng
  text: |-
    The problem of obtaining the maximum a posteriori estimate of a general discrete Markov random field (i.e., a Markov random field defined using a discrete set of labels) is known to be NP-hard. However, due to its central importance in many applications, several approximation algorithms have been proposed in the literature. In this paper, we present an analysis of three such algorithms based on convex relaxations: (i) LP-S: the linear programming (LP) relaxation proposed by Schlesinger (1976) for a special case and independently in Chekuri et al. (2001), Koster et al. (1998), and Wainwright et al. (2005) for the general case; (ii) QP-RL: the quadratic programming (QP) relaxation of Ravikumar and Lafferty (2006); and (iii) SOCP-MS: the second order cone programming (SOCP) relaxation first proposed by Muramatsu and Suzuki (2003) for two label problems and later extended by Kumar et al. (2006) for a general label set.

    We show that the SOCP-MS and the QP-RL relaxations are equivalent. Furthermore, we prove that despite the flexibility in the form of the constraints/objective function offered by QP and SOCP, the LP-S relaxation strictly dominates (i.e., provides a better approximation than) QP-RL and SOCP-MS. We generalize these results by defining a large class of SOCP (and equivalent QP) relaxations which is dominated by the LP-S relaxation. Based on these results we propose some novel SOCP relaxations which define constraints using random variables that form cycles or cliques in the graphical model representation of the random field. Using some examples we show that the new SOCP relaxations strictly dominate the previous approaches.
author:
- first_name: M Pawan
  full_name: Kumar, M Pawan
  last_name: Kumar
- first_name: Vladimir
  full_name: Vladimir Kolmogorov
  id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
  last_name: Kolmogorov
- first_name: Philip
  full_name: Torr, Philip H
  last_name: Torr
citation:
  ama: Kumar MP, Kolmogorov V, Torr P. An analysis of convex relaxations for MAP estimation
    of discrete MRFs. <i>Journal of Machine Learning Research</i>. 2009;10:71-106.
  apa: Kumar, M. P., Kolmogorov, V., &#38; Torr, P. (2009). An analysis of convex
    relaxations for MAP estimation of discrete MRFs. <i>Journal of Machine Learning
    Research</i>. Microtome Publishing.
  chicago: Kumar, M Pawan, Vladimir Kolmogorov, and Philip Torr. “An Analysis of Convex
    Relaxations for MAP Estimation of Discrete MRFs.” <i>Journal of Machine Learning
    Research</i>. Microtome Publishing, 2009.
  ieee: M. P. Kumar, V. Kolmogorov, and P. Torr, “An analysis of convex relaxations
    for MAP estimation of discrete MRFs,” <i>Journal of Machine Learning Research</i>,
    vol. 10. Microtome Publishing, pp. 71–106, 2009.
  ista: Kumar MP, Kolmogorov V, Torr P. 2009. An analysis of convex relaxations for
    MAP estimation of discrete MRFs. Journal of Machine Learning Research. 10, 71–106.
  mla: Kumar, M. Pawan, et al. “An Analysis of Convex Relaxations for MAP Estimation
    of Discrete MRFs.” <i>Journal of Machine Learning Research</i>, vol. 10, Microtome
    Publishing, 2009, pp. 71–106.
  short: M.P. Kumar, V. Kolmogorov, P. Torr, Journal of Machine Learning Research
    10 (2009) 71–106.
date_created: 2018-12-11T12:01:57Z
date_published: 2009-01-01T00:00:00Z
date_updated: 2021-01-12T07:41:44Z
day: '01'
extern: 1
intvolume: '        10'
main_file_link:
- open_access: '1'
  url: https://hal.inria.fr/hal-00773608
month: '01'
oa: 1
page: 71 - 106
publication: Journal of Machine Learning Research
publication_status: published
publisher: Microtome Publishing
publist_id: '3484'
quality_controlled: 0
status: public
title: An analysis of convex relaxations for MAP estimation of discrete MRFs
type: journal_article
volume: 10
year: '2009'
...
---
_id: '3199'
abstract:
- lang: eng
  text: Many interactive image segmentation approaches use an objective function which
    includes appearance models as an unknown variable. Since the resulting optimization
    problem is NP-hard the segmentation and appearance are typically optimized separately,
    in an EM-style fashion. One contribution of this paper is to express the objective
    function purely in terms of the unknown segmentation, using higher-order cliques.
    This formulation reveals an interesting bias of the model towards balanced segmentations.
    Furthermore, it enables us to develop a new dual decomposition optimization procedure,
    which provides additionally a lower bound. Hence, we are able to improve on existing
    optimizers, and verify that for a considerable number of real world examples we
    even achieve global optimality. This is important since we are able, for the first
    time, to analyze the deficiencies of the model. Another contribution is to establish
    a property of a particular dual decomposition approach which involves convex functions
    depending on foreground area. As a consequence, we show that the optimal decomposition
    for our problem can be computed efficiently via a parametric maxflow algorithm.
author:
- first_name: Sara
  full_name: Vicente, Sara
  last_name: Vicente
- first_name: Vladimir
  full_name: Vladimir Kolmogorov
  id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
  last_name: Kolmogorov
- first_name: Carsten
  full_name: Rother, Carsten
  last_name: Rother
citation:
  ama: 'Vicente S, Kolmogorov V, Rother C. Joint optimization of segmentation and
    appearance models. In: IEEE; 2009:755-762. doi:<a href="https://doi.org/10.1109/ICCV.2009.5459287">10.1109/ICCV.2009.5459287</a>'
  apa: 'Vicente, S., Kolmogorov, V., &#38; Rother, C. (2009). Joint optimization of
    segmentation and appearance models (pp. 755–762). Presented at the ICCV: International
    Conference on Computer Vision, IEEE. <a href="https://doi.org/10.1109/ICCV.2009.5459287">https://doi.org/10.1109/ICCV.2009.5459287</a>'
  chicago: Vicente, Sara, Vladimir Kolmogorov, and Carsten Rother. “Joint Optimization
    of Segmentation and Appearance Models,” 755–62. IEEE, 2009. <a href="https://doi.org/10.1109/ICCV.2009.5459287">https://doi.org/10.1109/ICCV.2009.5459287</a>.
  ieee: 'S. Vicente, V. Kolmogorov, and C. Rother, “Joint optimization of segmentation
    and appearance models,” presented at the ICCV: International Conference on Computer
    Vision, 2009, pp. 755–762.'
  ista: 'Vicente S, Kolmogorov V, Rother C. 2009. Joint optimization of segmentation
    and appearance models. ICCV: International Conference on Computer Vision, 755–762.'
  mla: Vicente, Sara, et al. <i>Joint Optimization of Segmentation and Appearance
    Models</i>. IEEE, 2009, pp. 755–62, doi:<a href="https://doi.org/10.1109/ICCV.2009.5459287">10.1109/ICCV.2009.5459287</a>.
  short: S. Vicente, V. Kolmogorov, C. Rother, in:, IEEE, 2009, pp. 755–762.
conference:
  name: 'ICCV: International Conference on Computer Vision'
date_created: 2018-12-11T12:01:58Z
date_published: 2009-05-01T00:00:00Z
date_updated: 2021-01-12T07:41:44Z
day: '01'
doi: 10.1109/ICCV.2009.5459287
extern: 1
main_file_link:
- open_access: '0'
  url: http://www.robots.ox.ac.uk/~vgg/rg/papers/segmentationappearance.pdf
month: '05'
page: 755 - 762
publication_status: published
publisher: IEEE
publist_id: '3482'
quality_controlled: 0
status: public
title: Joint optimization of segmentation and appearance models
type: conference
year: '2009'
...
---
_id: '3200'
abstract:
- lang: eng
  text: Motivated by various applications to computer vision, we consider the convex
    cost tension problem, which is the dual of the convex cost flow problem. In this
    paper, we first propose a primal algorithm for computing an optimal solution of
    the problem. Our primal algorithm iteratively updates primal variables by solving
    associated minimum cut problems. We show that the time complexity of the primal
    algorithm is O (K {dot operator} T (n, m)), where K is the range of primal variables
    and T (n, m) is the time needed to compute a minimum cut in a graph with n nodes
    and m edges. We then develop an improved version of the primal algorithm, called
    the primal-dual algorithm, by making good use of dual variables in addition to
    primal variables. Although its time complexity is the same as that of the primal
    algorithm, we can expect a better performance in practice. We finally consider
    an application to a computer vision problem called the panoramic image stitching.
author:
- first_name: Vladimir
  full_name: Vladimir Kolmogorov
  id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
  last_name: Kolmogorov
- first_name: Akiyoshi
  full_name: Shioura, Akiyoshi
  last_name: Shioura
citation:
  ama: Kolmogorov V, Shioura A. New algorithms for convex cost tension problem with
    application to computer vision. <i>Discrete Optimization</i>. 2009;6(4):378-393.
    doi:<a href="https://doi.org/10.1016/j.disopt.2009.04.006">10.1016/j.disopt.2009.04.006</a>
  apa: Kolmogorov, V., &#38; Shioura, A. (2009). New algorithms for convex cost tension
    problem with application to computer vision. <i>Discrete Optimization</i>. Elsevier.
    <a href="https://doi.org/10.1016/j.disopt.2009.04.006">https://doi.org/10.1016/j.disopt.2009.04.006</a>
  chicago: Kolmogorov, Vladimir, and Akiyoshi Shioura. “New Algorithms for Convex
    Cost Tension Problem with Application to Computer Vision.” <i>Discrete Optimization</i>.
    Elsevier, 2009. <a href="https://doi.org/10.1016/j.disopt.2009.04.006">https://doi.org/10.1016/j.disopt.2009.04.006</a>.
  ieee: V. Kolmogorov and A. Shioura, “New algorithms for convex cost tension problem
    with application to computer vision,” <i>Discrete Optimization</i>, vol. 6, no.
    4. Elsevier, pp. 378–393, 2009.
  ista: Kolmogorov V, Shioura A. 2009. New algorithms for convex cost tension problem
    with application to computer vision. Discrete Optimization. 6(4), 378–393.
  mla: Kolmogorov, Vladimir, and Akiyoshi Shioura. “New Algorithms for Convex Cost
    Tension Problem with Application to Computer Vision.” <i>Discrete Optimization</i>,
    vol. 6, no. 4, Elsevier, 2009, pp. 378–93, doi:<a href="https://doi.org/10.1016/j.disopt.2009.04.006">10.1016/j.disopt.2009.04.006</a>.
  short: V. Kolmogorov, A. Shioura, Discrete Optimization 6 (2009) 378–393.
date_created: 2018-12-11T12:01:58Z
date_published: 2009-11-01T00:00:00Z
date_updated: 2021-01-12T07:41:45Z
day: '01'
doi: 10.1016/j.disopt.2009.04.006
extern: 1
intvolume: '         6'
issue: '4'
month: '11'
page: 378 - 393
publication: Discrete Optimization
publication_status: published
publisher: Elsevier
publist_id: '3483'
quality_controlled: 0
status: public
title: New algorithms for convex cost tension problem with application to computer
  vision
type: journal_article
volume: 6
year: '2009'
...
