---
_id: '3868'
abstract:
- lang: eng
text: Simulation and bisimulation metrics for stochastic systems provide a quantitative
generalization of the classical simulation and bisimulation relations. These metrics
capture the similarity of states with respect to quantitative specifications written
in the quantitative mu-calculus and related probabilistic logics. We first show
that the metrics provide a bound for the difference in long-run average and discounted
average behavior across states, indicating that the metrics can be used both in
system verification, and in performance evaluation. For turn-based games and MDPs,
we provide a polynomial-time algorithm for the computation of the one-step metric
distance between states. The algorithm is based on linear programming; it improves
on the previous known exponential-time algorithm based on a reduction to the theory
of reals. We then present PSPACE algorithms for both the decision problem and
the problem of approximating the metric distance between two states, matching
the best known algorithms for Markov chains. For the bisimulation kernel of the
metric our algorithm works in time O(n(4)) for both turn-based games and MDPs;
improving the previously best known O(n(9).log(n)) time algorithm for MDPs. For
a concurrent game G, we show that computing the exact distance be tween states
is at least as hard as computing the value of concurrent reachability games and
the square-root-sum problem in computational geometry. We show that checking whether
the metric distance is bounded by a rational r, can be done via a reduction to
the theory of real closed fields, involving a formula with three quantifier alternations,
yielding O(vertical bar G vertical bar(O(vertical bar G vertical bar 5))) time
complexity, improving the previously known reduction, which yielded O(vertical
bar G vertical bar(O(vertical bar G vertical bar 7))) time complexity. These algorithms
can be iterated to approximate the metrics using binary search
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Luca
full_name: De Alfaro, Luca
last_name: De Alfaro
- first_name: Ritankar
full_name: Majumdar, Ritankar
last_name: Majumdar
- first_name: Vishwanath
full_name: Raman, Vishwanath
last_name: Raman
citation:
ama: Chatterjee K, De Alfaro L, Majumdar R, Raman V. Algorithms for game metrics.
Logical Methods in Computer Science. 2010;6(3):1-27. doi:10.2168/LMCS-6(3:13)2010
apa: Chatterjee, K., De Alfaro, L., Majumdar, R., & Raman, V. (2010). Algorithms
for game metrics. Logical Methods in Computer Science. International Federation
of Computational Logic. https://doi.org/10.2168/LMCS-6(3:13)2010
chicago: Chatterjee, Krishnendu, Luca De Alfaro, Ritankar Majumdar, and Vishwanath
Raman. “Algorithms for Game Metrics.” Logical Methods in Computer Science.
International Federation of Computational Logic, 2010. https://doi.org/10.2168/LMCS-6(3:13)2010.
ieee: K. Chatterjee, L. De Alfaro, R. Majumdar, and V. Raman, “Algorithms for game
metrics,” Logical Methods in Computer Science, vol. 6, no. 3. International
Federation of Computational Logic, pp. 1–27, 2010.
ista: Chatterjee K, De Alfaro L, Majumdar R, Raman V. 2010. Algorithms for game
metrics. Logical Methods in Computer Science. 6(3), 1–27.
mla: Chatterjee, Krishnendu, et al. “Algorithms for Game Metrics.” Logical Methods
in Computer Science, vol. 6, no. 3, International Federation of Computational
Logic, 2010, pp. 1–27, doi:10.2168/LMCS-6(3:13)2010.
short: K. Chatterjee, L. De Alfaro, R. Majumdar, V. Raman, Logical Methods in Computer
Science 6 (2010) 1–27.
date_created: 2018-12-11T12:05:36Z
date_published: 2010-09-01T00:00:00Z
date_updated: 2023-02-23T11:30:18Z
day: '01'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.2168/LMCS-6(3:13)2010
file:
- access_level: open_access
checksum: a18988135fef3016c93808ecb15b55f5
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:08:11Z
date_updated: 2020-07-14T12:46:19Z
file_id: '4671'
file_name: IST-2015-370-v1+1_0809.4326.pdf
file_size: 346527
relation: main_file
file_date_updated: 2020-07-14T12:46:19Z
has_accepted_license: '1'
intvolume: ' 6'
issue: '3'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nd/4.0/
month: '09'
oa: 1
oa_version: Published Version
page: 1 - 27
publication: Logical Methods in Computer Science
publication_status: published
publisher: International Federation of Computational Logic
publist_id: '2312'
pubrep_id: '370'
quality_controlled: '1'
related_material:
record:
- id: '3504'
relation: earlier_version
status: public
scopus_import: 1
status: public
title: Algorithms for game metrics
tmp:
image: /image/cc_by_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nd/4.0/legalcode
name: Creative Commons Attribution-NoDerivatives 4.0 International (CC BY-ND 4.0)
short: CC BY-ND (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2010'
...
---
_id: '3899'
abstract:
- lang: eng
text: 'Combining concepts from topology and algorithms, this book delivers what
its title promises: an introduction to the field of computational topology. Starting
with motivating problems in both mathematics and computer science and building
up from classic topics in geometric and algebraic topology, the third part of
the text advances to persistent homology. This point of view is critically important
in turning a mostly theoretical field of mathematics into one that is relevant
to a multitude of disciplines in the sciences and engineering. The main approach
is the discovery of topology through algorithms. The book is ideal for teaching
a graduate or advanced undergraduate course in computational topology, as it develops
all the background of both the mathematical and algorithmic aspects of the subject
from first principles. Thus the text could serve equally well in a course taught
in a mathematics department or computer science department.'
article_processing_charge: No
author:
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: John
full_name: Harer, John
last_name: Harer
citation:
ama: 'Edelsbrunner H, Harer J. Computational Topology: An Introduction. Vol
69. American Mathematical Society; 2010. doi:10.1090/mbk/069'
apa: 'Edelsbrunner, H., & Harer, J. (2010). Computational Topology: An Introduction
(Vol. 69). American Mathematical Society. https://doi.org/10.1090/mbk/069'
chicago: 'Edelsbrunner, Herbert, and John Harer. Computational Topology: An Introduction.
Vol. 69. American Mathematical Society, 2010. https://doi.org/10.1090/mbk/069.'
ieee: 'H. Edelsbrunner and J. Harer, Computational Topology: An Introduction,
vol. 69. American Mathematical Society, 2010.'
ista: 'Edelsbrunner H, Harer J. 2010. Computational Topology: An Introduction, American
Mathematical Society, XII, 241p.'
mla: 'Edelsbrunner, Herbert, and John Harer. Computational Topology: An Introduction.
Vol. 69, American Mathematical Society, 2010, doi:10.1090/mbk/069.'
short: 'H. Edelsbrunner, J. Harer, Computational Topology: An Introduction, American
Mathematical Society, 2010.'
date_created: 2018-12-11T12:05:46Z
date_published: 2010-01-15T00:00:00Z
date_updated: 2021-12-21T12:26:50Z
day: '15'
doi: 10.1090/mbk/069
extern: '1'
intvolume: ' 69'
language:
- iso: eng
main_file_link:
- url: https://www.ams.org/books/mbk/069/
month: '01'
oa_version: None
page: XII, 241
publication_identifier:
eisbn:
- 978-1-4704-1208-1
isbn:
- 978-0-8218-4925-5
publication_status: published
publisher: American Mathematical Society
publist_id: '2258'
quality_controlled: '1'
related_material:
link:
- description: available via catalog IST BookList
relation: other
url: https://koha.app.ist.ac.at/cgi-bin/koha/opac-detail.pl?biblionumber=3289
status: public
title: 'Computational Topology: An Introduction'
type: book
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 69
year: '2010'
...
---
_id: '3901'
abstract:
- lang: eng
text: We are interested in 3-dimensional images given as arrays of voxels with intensity
values. Extending these values to acontinuous function, we study the robustness
of homology classes in its level and interlevel sets, that is, the amount of perturbationneeded
to destroy these classes. The structure of the homology classes and their robustness,
over all level and interlevel sets, can bevisualized by a triangular diagram of
dots obtained by computing the extended persistence of the function. We give a
fast hierarchicalalgorithm using the dual complexes of oct-tree approximations
of the function. In addition, we show that for balanced oct-trees, thedual complexes
are geometrically realized in $R^3$ and can thus be used to construct level and
interlevel sets. We apply these tools tostudy 3-dimensional images of plant root
systems.
author:
- first_name: Paul
full_name: Bendich, Paul
id: 43F6EC54-F248-11E8-B48F-1D18A9856A87
last_name: Bendich
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Michael
full_name: Kerber, Michael
id: 36E4574A-F248-11E8-B48F-1D18A9856A87
last_name: Kerber
orcid: 0000-0002-8030-9299
citation:
ama: Bendich P, Edelsbrunner H, Kerber M. Computing robustness and persistence for
images. IEEE Transactions of Visualization and Computer Graphics. 2010;16(6):1251-1260.
doi:10.1109/TVCG.2010.139
apa: Bendich, P., Edelsbrunner, H., & Kerber, M. (2010). Computing robustness
and persistence for images. IEEE Transactions of Visualization and Computer
Graphics. IEEE. https://doi.org/10.1109/TVCG.2010.139
chicago: Bendich, Paul, Herbert Edelsbrunner, and Michael Kerber. “Computing Robustness
and Persistence for Images.” IEEE Transactions of Visualization and Computer
Graphics. IEEE, 2010. https://doi.org/10.1109/TVCG.2010.139.
ieee: P. Bendich, H. Edelsbrunner, and M. Kerber, “Computing robustness and persistence
for images,” IEEE Transactions of Visualization and Computer Graphics,
vol. 16, no. 6. IEEE, pp. 1251–1260, 2010.
ista: Bendich P, Edelsbrunner H, Kerber M. 2010. Computing robustness and persistence
for images. IEEE Transactions of Visualization and Computer Graphics. 16(6), 1251–1260.
mla: Bendich, Paul, et al. “Computing Robustness and Persistence for Images.” IEEE
Transactions of Visualization and Computer Graphics, vol. 16, no. 6, IEEE,
2010, pp. 1251–60, doi:10.1109/TVCG.2010.139.
short: P. Bendich, H. Edelsbrunner, M. Kerber, IEEE Transactions of Visualization
and Computer Graphics 16 (2010) 1251–1260.
date_created: 2018-12-11T12:05:47Z
date_published: 2010-10-28T00:00:00Z
date_updated: 2021-01-12T07:53:04Z
day: '28'
ddc:
- '000'
department:
- _id: HeEd
doi: 10.1109/TVCG.2010.139
file:
- access_level: open_access
checksum: f6d813c04f4b46023cec6b9a17f15472
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:17:10Z
date_updated: 2020-07-14T12:46:21Z
file_id: '5262'
file_name: IST-2016-536-v1+1_2010-J-02-PersistenceforImages.pdf
file_size: 721994
relation: main_file
file_date_updated: 2020-07-14T12:46:21Z
has_accepted_license: '1'
intvolume: ' 16'
issue: '6'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Submitted Version
page: 1251 - 1260
publication: IEEE Transactions of Visualization and Computer Graphics
publication_status: published
publisher: IEEE
publist_id: '2253'
pubrep_id: '536'
quality_controlled: '1'
scopus_import: 1
status: public
title: Computing robustness and persistence for images
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 16
year: '2010'
...
---
_id: '3904'
abstract:
- lang: eng
text: Social organisms are constantly exposed to infectious agents via physical
contact with conspecifics. While previous work has shown that disease susceptibility
at the individual and group level is influenced by gen- etic diversity within
and between group members, it remains poorly understood how group-level resistance
to pathogens relates directly to individual physiology, defence behaviour and
social interactions. We investigated the effects of high versus low genetic diversity
on both the individual and collective disease defences in the ant Cardiocondyla
obscurior. We compared the antiseptic behaviours (grooming and hygienic behaviour)
of workers from genetically homogeneous and diverse colonies after exposure of
their brood to the entomopathogenic fungus Metarhizium anisopliae. While workers
from diverse colonies performed intensive allogrooming and quickly removed larvae
covered with live fungal spores from the nest, workers from homogeneous colonies
only removed sick larvae late after infection. This difference was not caused
by a reduced repertoire of antiseptic behaviours or a generally decreased brood
care activity in ants from homogeneous colonies. Our data instead suggest that
reduced genetic diversity compromises the ability of Cardiocondyla colonies to
quickly detect or react to the presence of pathogenic fungal spores before an
infection is established, thereby affecting the dynamics of social immunity in
the colony.
author:
- first_name: Line V
full_name: Ugelvig, Line V
id: 3DC97C8E-F248-11E8-B48F-1D18A9856A87
last_name: Ugelvig
orcid: 0000-0003-1832-8883
- first_name: Daniel
full_name: Kronauer, Daniel
last_name: Kronauer
- first_name: Alexandra
full_name: Schrempf, Alexandra
last_name: Schrempf
- first_name: Jürgen
full_name: Heinze, Jürgen
last_name: Heinze
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
citation:
ama: Ugelvig LV, Kronauer D, Schrempf A, Heinze J, Cremer S. Rapid anti-pathogen
response in ant societies relies on high genetic diversity. Proceedings of
the Royal Society of London Series B Biological Sciences. 2010;277(1695):2821-2828.
doi:10.1098/rspb.2010.0644
apa: Ugelvig, L. V., Kronauer, D., Schrempf, A., Heinze, J., & Cremer, S. (2010).
Rapid anti-pathogen response in ant societies relies on high genetic diversity.
Proceedings of the Royal Society of London Series B Biological Sciences.
Royal Society, The. https://doi.org/10.1098/rspb.2010.0644
chicago: Ugelvig, Line V, Daniel Kronauer, Alexandra Schrempf, Jürgen Heinze, and
Sylvia Cremer. “Rapid Anti-Pathogen Response in Ant Societies Relies on High Genetic
Diversity.” Proceedings of the Royal Society of London Series B Biological
Sciences. Royal Society, The, 2010. https://doi.org/10.1098/rspb.2010.0644.
ieee: L. V. Ugelvig, D. Kronauer, A. Schrempf, J. Heinze, and S. Cremer, “Rapid
anti-pathogen response in ant societies relies on high genetic diversity,” Proceedings
of the Royal Society of London Series B Biological Sciences, vol. 277, no.
1695. Royal Society, The, pp. 2821–2828, 2010.
ista: Ugelvig LV, Kronauer D, Schrempf A, Heinze J, Cremer S. 2010. Rapid anti-pathogen
response in ant societies relies on high genetic diversity. Proceedings of the
Royal Society of London Series B Biological Sciences. 277(1695), 2821–2828.
mla: Ugelvig, Line V., et al. “Rapid Anti-Pathogen Response in Ant Societies Relies
on High Genetic Diversity.” Proceedings of the Royal Society of London Series
B Biological Sciences, vol. 277, no. 1695, Royal Society, The, 2010, pp. 2821–28,
doi:10.1098/rspb.2010.0644.
short: L.V. Ugelvig, D. Kronauer, A. Schrempf, J. Heinze, S. Cremer, Proceedings
of the Royal Society of London Series B Biological Sciences 277 (2010) 2821–2828.
date_created: 2018-12-11T12:05:48Z
date_published: 2010-05-05T00:00:00Z
date_updated: 2021-01-12T07:53:05Z
day: '05'
doi: 10.1098/rspb.2010.0644
extern: '1'
intvolume: ' 277'
issue: '1695'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981995/
month: '05'
oa: 1
oa_version: None
page: 2821 - 2828
publication: Proceedings of the Royal Society of London Series B Biological Sciences
publication_status: published
publisher: Royal Society, The
publist_id: '2251'
status: public
title: Rapid anti-pathogen response in ant societies relies on high genetic diversity
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 277
year: '2010'
...
---
_id: '3956'
abstract:
- lang: eng
text: The shuttling of leukocytes between the bloodstream and interstitial tissues
involves different locomotion strategies that are governed by locally presented
soluble and cell-bound signals. Recent studies have furthered our understanding
of the rapidly advancing field of leukocyte migration, particularly regarding
cellular and subcellular events at the level of the venular wall. Furthermore,
emerging cellular models are now addressing the transition from an adherent mode
to a non-adherent state, incorporating mechanisms that support an efficient migratory
profile of leukocytes in the interstitial tissue beyond the venular wall.
author:
- first_name: Sussan
full_name: Nourshargh, Sussan
last_name: Nourshargh
- first_name: Peter
full_name: Hordijk, Peter L
last_name: Hordijk
- first_name: Michael K
full_name: Michael Sixt
id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
last_name: Sixt
orcid: 0000-0002-6620-9179
citation:
ama: 'Nourshargh S, Hordijk P, Sixt MK. Breaching multiple barriers: leukocyte motility
through venular walls and the interstitium. Nature Reviews Molecular Cell Biology.
2010;11(5):366-378. doi:10.1038/nrm2889'
apa: 'Nourshargh, S., Hordijk, P., & Sixt, M. K. (2010). Breaching multiple
barriers: leukocyte motility through venular walls and the interstitium. Nature
Reviews Molecular Cell Biology. Nature Publishing Group. https://doi.org/10.1038/nrm2889'
chicago: 'Nourshargh, Sussan, Peter Hordijk, and Michael K Sixt. “Breaching Multiple
Barriers: Leukocyte Motility through Venular Walls and the Interstitium.” Nature
Reviews Molecular Cell Biology. Nature Publishing Group, 2010. https://doi.org/10.1038/nrm2889.'
ieee: 'S. Nourshargh, P. Hordijk, and M. K. Sixt, “Breaching multiple barriers:
leukocyte motility through venular walls and the interstitium,” Nature Reviews
Molecular Cell Biology, vol. 11, no. 5. Nature Publishing Group, pp. 366–378,
2010.'
ista: 'Nourshargh S, Hordijk P, Sixt MK. 2010. Breaching multiple barriers: leukocyte
motility through venular walls and the interstitium. Nature Reviews Molecular
Cell Biology. 11(5), 366–378.'
mla: 'Nourshargh, Sussan, et al. “Breaching Multiple Barriers: Leukocyte Motility
through Venular Walls and the Interstitium.” Nature Reviews Molecular Cell
Biology, vol. 11, no. 5, Nature Publishing Group, 2010, pp. 366–78, doi:10.1038/nrm2889.'
short: S. Nourshargh, P. Hordijk, M.K. Sixt, Nature Reviews Molecular Cell Biology
11 (2010) 366–378.
date_created: 2018-12-11T12:06:06Z
date_published: 2010-05-01T00:00:00Z
date_updated: 2021-01-12T07:53:27Z
day: '01'
doi: 10.1038/nrm2889
extern: 1
intvolume: ' 11'
issue: '5'
month: '05'
page: 366 - 378
publication: Nature Reviews Molecular Cell Biology
publication_status: published
publisher: Nature Publishing Group
publist_id: '2170'
quality_controlled: 0
status: public
title: 'Breaching multiple barriers: leukocyte motility through venular walls and
the interstitium'
type: journal_article
volume: 11
year: '2010'
...
---
_id: '3957'
author:
- first_name: Julia
full_name: Riedl, Julia
last_name: Riedl
- first_name: Kevin
full_name: Flynn, Kevin C
last_name: Flynn
- first_name: Aurelia
full_name: Raducanu, Aurelia
last_name: Raducanu
- first_name: Florian R
full_name: Florian Gärtner
id: 397A88EE-F248-11E8-B48F-1D18A9856A87
last_name: Gärtner
orcid: 0000-0001-6120-3723
- first_name: Gisela
full_name: Beck, Gisela
last_name: Beck
- first_name: Michael
full_name: Bosl, Michael
last_name: Bosl
- first_name: Frank
full_name: Bradke, Frank
last_name: Bradke
- first_name: Steffen
full_name: Massberg, Steffen
last_name: Massberg
- first_name: Attila
full_name: Aszodi, Attila
last_name: Aszodi
- first_name: Michael K
full_name: Michael Sixt
id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
last_name: Sixt
orcid: 0000-0002-6620-9179
- first_name: Roland
full_name: Wedlich-Söldner, Roland
last_name: Wedlich Söldner
citation:
ama: Riedl J, Flynn K, Raducanu A, et al. Lifeact mice for studying F-actin dynamics.
Nature Methods. 2010;7(3):168-169. doi:10.1038/nmeth0310-168
apa: Riedl, J., Flynn, K., Raducanu, A., Gärtner, F. R., Beck, G., Bosl, M., … Wedlich
Söldner, R. (2010). Lifeact mice for studying F-actin dynamics. Nature Methods.
Nature Publishing Group. https://doi.org/10.1038/nmeth0310-168
chicago: Riedl, Julia, Kevin Flynn, Aurelia Raducanu, Florian R Gärtner, Gisela
Beck, Michael Bosl, Frank Bradke, et al. “Lifeact Mice for Studying F-Actin Dynamics.”
Nature Methods. Nature Publishing Group, 2010. https://doi.org/10.1038/nmeth0310-168.
ieee: J. Riedl et al., “Lifeact mice for studying F-actin dynamics,” Nature
Methods, vol. 7, no. 3. Nature Publishing Group, pp. 168–169, 2010.
ista: Riedl J, Flynn K, Raducanu A, Gärtner FR, Beck G, Bosl M, Bradke F, Massberg
S, Aszodi A, Sixt MK, Wedlich Söldner R. 2010. Lifeact mice for studying F-actin
dynamics. Nature Methods. 7(3), 168–169.
mla: Riedl, Julia, et al. “Lifeact Mice for Studying F-Actin Dynamics.” Nature
Methods, vol. 7, no. 3, Nature Publishing Group, 2010, pp. 168–69, doi:10.1038/nmeth0310-168.
short: J. Riedl, K. Flynn, A. Raducanu, F.R. Gärtner, G. Beck, M. Bosl, F. Bradke,
S. Massberg, A. Aszodi, M.K. Sixt, R. Wedlich Söldner, Nature Methods 7 (2010)
168–169.
date_created: 2018-12-11T12:06:06Z
date_published: 2010-03-01T00:00:00Z
date_updated: 2021-01-12T07:53:28Z
day: '01'
doi: 10.1038/nmeth0310-168
extern: 1
intvolume: ' 7'
issue: '3'
month: '03'
page: 168 - 169
publication: Nature Methods
publication_status: published
publisher: Nature Publishing Group
publist_id: '2171'
quality_controlled: 0
status: public
title: Lifeact mice for studying F-actin dynamics
type: journal_article
volume: 7
year: '2010'
...
---
_id: '3958'
abstract:
- lang: eng
text: Extracellular matrix (ECM) proteins can modify immune reactions, e.g. by sequestering
or displaying growth factors and by interacting with immune and glial cells. Here
we quantified by quantitative polymerase chain reaction (qPCR) expression of 50
ECM components and 34 ECM degrading enzymes in multiple sclerosis (MS) active
and inactive white matter lesions. COL1A1, COL3A1, COL5A1 and COL5A2 chains were
induced strongly in active lesions and even more in inactive lesions. These chains
interact to form collagen types I, III and V, which are fibrillar collagens. Biglycan
and decorin, which can decorate fibrillar collagens, were also induced strongly.
The fibrillar collagens, biglycan and decorin were largely found between the endothelium
and astrocytic glia limitans in the perivascular space where they formed a meshwork
which was closely associated with infiltrating immune cells. In active lesions
collagen V was also seen in the heavily infiltrated parenchyma. Fibrillar collagens
I and III inhibited in vitro human monocyte production of CCL2 (MCP-1), an inflammatory
chemokine involved in recruitment of immune cells. Together, ECM changes in lesions
with different activities were quantified and proteins forming a perivascular
fibrosis were identified. Induced fibrillar collagens may contribute to limiting
enlargement of MS lesions by inhibiting the production of CCL2 by monocytes.
author:
- first_name: Hema
full_name: Mohan, Hema
last_name: Mohan
- first_name: Markus
full_name: Krumbholz, Markus
last_name: Krumbholz
- first_name: Rakhi
full_name: Sharma, Rakhi
last_name: Sharma
- first_name: Sylvia
full_name: Eisele, Sylvia
last_name: Eisele
- first_name: Andreas
full_name: Junker, Andreas
last_name: Junker
- first_name: Michael K
full_name: Michael Sixt
id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
last_name: Sixt
orcid: 0000-0002-6620-9179
- first_name: Jia
full_name: Newcombe, Jia
last_name: Newcombe
- first_name: Hartmut
full_name: Wekerle, Hartmut
last_name: Wekerle
- first_name: Reinhard
full_name: Hohlfeld, Reinhard
last_name: Hohlfeld
- first_name: Hans
full_name: Lassmann, Hans
last_name: Lassmann
- first_name: Edgar
full_name: Meinl, Edgar
last_name: Meinl
citation:
ama: 'Mohan H, Krumbholz M, Sharma R, et al. Extracellular matrix in multiple sclerosis
lesions: fibrillar collagens, biglycan and decorin are upregulated and associated
with infiltrating immune cells. Brain Pathology. 2010;20(5):966-975. doi:10.1111/j.1750-3639.2010.00399.x'
apa: 'Mohan, H., Krumbholz, M., Sharma, R., Eisele, S., Junker, A., Sixt, M. K.,
… Meinl, E. (2010). Extracellular matrix in multiple sclerosis lesions: fibrillar
collagens, biglycan and decorin are upregulated and associated with infiltrating
immune cells. Brain Pathology. Wiley-Blackwell. https://doi.org/10.1111/j.1750-3639.2010.00399.x'
chicago: 'Mohan, Hema, Markus Krumbholz, Rakhi Sharma, Sylvia Eisele, Andreas Junker,
Michael K Sixt, Jia Newcombe, et al. “Extracellular Matrix in Multiple Sclerosis
Lesions: Fibrillar Collagens, Biglycan and Decorin Are Upregulated and Associated
with Infiltrating Immune Cells.” Brain Pathology. Wiley-Blackwell, 2010.
https://doi.org/10.1111/j.1750-3639.2010.00399.x.'
ieee: 'H. Mohan et al., “Extracellular matrix in multiple sclerosis lesions:
fibrillar collagens, biglycan and decorin are upregulated and associated with
infiltrating immune cells,” Brain Pathology, vol. 20, no. 5. Wiley-Blackwell,
pp. 966–975, 2010.'
ista: 'Mohan H, Krumbholz M, Sharma R, Eisele S, Junker A, Sixt MK, Newcombe J,
Wekerle H, Hohlfeld R, Lassmann H, Meinl E. 2010. Extracellular matrix in multiple
sclerosis lesions: fibrillar collagens, biglycan and decorin are upregulated and
associated with infiltrating immune cells. Brain Pathology. 20(5), 966–975.'
mla: 'Mohan, Hema, et al. “Extracellular Matrix in Multiple Sclerosis Lesions: Fibrillar
Collagens, Biglycan and Decorin Are Upregulated and Associated with Infiltrating
Immune Cells.” Brain Pathology, vol. 20, no. 5, Wiley-Blackwell, 2010,
pp. 966–75, doi:10.1111/j.1750-3639.2010.00399.x.'
short: H. Mohan, M. Krumbholz, R. Sharma, S. Eisele, A. Junker, M.K. Sixt, J. Newcombe,
H. Wekerle, R. Hohlfeld, H. Lassmann, E. Meinl, Brain Pathology 20 (2010) 966–975.
date_created: 2018-12-11T12:06:07Z
date_published: 2010-09-01T00:00:00Z
date_updated: 2021-01-12T07:53:28Z
day: '01'
doi: 10.1111/j.1750-3639.2010.00399.x
extern: 1
intvolume: ' 20'
issue: '5'
month: '09'
page: 966 - 975
publication: Brain Pathology
publication_status: published
publisher: Wiley-Blackwell
publist_id: '2169'
quality_controlled: 0
status: public
title: 'Extracellular matrix in multiple sclerosis lesions: fibrillar collagens, biglycan
and decorin are upregulated and associated with infiltrating immune cells'
type: journal_article
volume: 20
year: '2010'
...
---
_id: '3959'
abstract:
- lang: eng
text: Chemokines orchestrate immune cell trafficking by eliciting either directed
or random migration and by activating integrins in order to induce cell adhesion.
Analyzing dendritic cell (DC) migration, we showed that these distinct cellular
responses depended on the mode of chemokine presentation within tissues. The surface-immobilized
form of the chemokine CCL21, the heparan sulfate-anchoring ligand of the CC-chemokine
receptor 7 (CCR7), caused random movement of DCs that was confined to the chemokine-presenting
surface because it triggered integrin-mediated adhesion. Upon direct contact with
CCL21, DCs truncated the anchoring residues of CCL21, thereby releasing it from
the solid phase. Soluble CCL21 functionally resembles the second CCR7 ligand,
CCL19, which lacks anchoring residues and forms soluble gradients. Both soluble
CCR7 ligands triggered chemotactic movement, but not surface adhesion. Adhesive
random migration and directional steering cooperate to produce dynamic but spatially
restricted locomotion patterns closely resembling the cellular dynamics observed
in secondary lymphoid organs.
author:
- first_name: Kathrin
full_name: Schumann, Kathrin
id: F44D762E-4F9D-11E9-B64C-9EB26CEFFB5F
last_name: Schumann
- first_name: Tim
full_name: Lämmermann, Tim
last_name: Lämmermann
- first_name: Markus
full_name: Bruckner, Markus
last_name: Bruckner
- first_name: Daniel
full_name: Legler, Daniel
last_name: Legler
- first_name: Julien
full_name: Polleux, Julien
last_name: Polleux
- first_name: Joachim
full_name: Spatz, Joachim
last_name: Spatz
- first_name: Gerold
full_name: Schuler, Gerold
last_name: Schuler
- first_name: Reinhold
full_name: Förster, Reinhold
last_name: Förster
- first_name: Manfred
full_name: Lutz, Manfred
last_name: Lutz
- first_name: Lydia
full_name: Sorokin, Lydia
last_name: Sorokin
- first_name: Michael K
full_name: Sixt, Michael K
id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
last_name: Sixt
orcid: 0000-0002-6620-9179
citation:
ama: Schumann K, Lämmermann T, Bruckner M, et al. Immobilized chemokine fields and
soluble chemokine gradients cooperatively shape migration patterns of dendritic
cells. Immunity. 2010;32(5):703-713. doi:10.1016/j.immuni.2010.04.017
apa: Schumann, K., Lämmermann, T., Bruckner, M., Legler, D., Polleux, J., Spatz,
J., … Sixt, M. K. (2010). Immobilized chemokine fields and soluble chemokine gradients
cooperatively shape migration patterns of dendritic cells. Immunity. Cell
Press. https://doi.org/10.1016/j.immuni.2010.04.017
chicago: Schumann, Kathrin, Tim Lämmermann, Markus Bruckner, Daniel Legler, Julien
Polleux, Joachim Spatz, Gerold Schuler, et al. “Immobilized Chemokine Fields and
Soluble Chemokine Gradients Cooperatively Shape Migration Patterns of Dendritic
Cells.” Immunity. Cell Press, 2010. https://doi.org/10.1016/j.immuni.2010.04.017.
ieee: K. Schumann et al., “Immobilized chemokine fields and soluble chemokine
gradients cooperatively shape migration patterns of dendritic cells,” Immunity,
vol. 32, no. 5. Cell Press, pp. 703–713, 2010.
ista: Schumann K, Lämmermann T, Bruckner M, Legler D, Polleux J, Spatz J, Schuler
G, Förster R, Lutz M, Sorokin L, Sixt MK. 2010. Immobilized chemokine fields and
soluble chemokine gradients cooperatively shape migration patterns of dendritic
cells. Immunity. 32(5), 703–713.
mla: Schumann, Kathrin, et al. “Immobilized Chemokine Fields and Soluble Chemokine
Gradients Cooperatively Shape Migration Patterns of Dendritic Cells.” Immunity,
vol. 32, no. 5, Cell Press, 2010, pp. 703–13, doi:10.1016/j.immuni.2010.04.017.
short: K. Schumann, T. Lämmermann, M. Bruckner, D. Legler, J. Polleux, J. Spatz,
G. Schuler, R. Förster, M. Lutz, L. Sorokin, M.K. Sixt, Immunity 32 (2010) 703–713.
date_created: 2018-12-11T12:06:07Z
date_published: 2010-05-28T00:00:00Z
date_updated: 2021-01-12T07:53:29Z
day: '28'
doi: 10.1016/j.immuni.2010.04.017
extern: '1'
intvolume: ' 32'
issue: '5'
language:
- iso: eng
month: '05'
oa_version: None
page: 703 - 713
publication: Immunity
publication_status: published
publisher: Cell Press
publist_id: '2168'
status: public
title: Immobilized chemokine fields and soluble chemokine gradients cooperatively
shape migration patterns of dendritic cells
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 32
year: '2010'
...
---
_id: '3960'
abstract:
- lang: eng
text: When lymphocytes follow chemotactic cues, they can adopt different migratory
modes depending on the geometry and molecular composition of their extracellular
environment. In this issue of The EMBO Journal, Klemke et al (2010) describe a
novel Ras-dependent chemokine receptor signalling pathway that leads to activation
of cofilin, which in turn amplifies actin turnover. This signalling module is
exclusively required for lymphocyte migration in three-dimensional (3D) environments,
but not for locomotion on two-dimensional (2D) surfaces.
author:
- first_name: Michele
full_name: Michele Weber
id: 3A3FC708-F248-11E8-B48F-1D18A9856A87
last_name: Weber
- first_name: Michael K
full_name: Michael Sixt
id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
last_name: Sixt
orcid: 0000-0002-6620-9179
citation:
ama: Weber M, Sixt MK. MEK signalling tunes actin treadmilling for interstitial
lymphocyte migration. EMBO Journal. 2010;29(17):2861-2863. doi:10.1038/emboj.2010.183
apa: Weber, M., & Sixt, M. K. (2010). MEK signalling tunes actin treadmilling
for interstitial lymphocyte migration. EMBO Journal. Wiley-Blackwell. https://doi.org/10.1038/emboj.2010.183
chicago: Weber, Michele, and Michael K Sixt. “MEK Signalling Tunes Actin Treadmilling
for Interstitial Lymphocyte Migration.” EMBO Journal. Wiley-Blackwell,
2010. https://doi.org/10.1038/emboj.2010.183.
ieee: M. Weber and M. K. Sixt, “MEK signalling tunes actin treadmilling for interstitial
lymphocyte migration,” EMBO Journal, vol. 29, no. 17. Wiley-Blackwell,
pp. 2861–2863, 2010.
ista: Weber M, Sixt MK. 2010. MEK signalling tunes actin treadmilling for interstitial
lymphocyte migration. EMBO Journal. 29(17), 2861–2863.
mla: Weber, Michele, and Michael K. Sixt. “MEK Signalling Tunes Actin Treadmilling
for Interstitial Lymphocyte Migration.” EMBO Journal, vol. 29, no. 17,
Wiley-Blackwell, 2010, pp. 2861–63, doi:10.1038/emboj.2010.183.
short: M. Weber, M.K. Sixt, EMBO Journal 29 (2010) 2861–2863.
date_created: 2018-12-11T12:06:07Z
date_published: 2010-09-01T00:00:00Z
date_updated: 2021-01-12T07:53:29Z
day: '01'
doi: 10.1038/emboj.2010.183
extern: 1
intvolume: ' 29'
issue: '17'
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/issues/190105/
month: '09'
oa: 1
page: 2861 - 2863
publication: EMBO Journal
publication_status: published
publisher: Wiley-Blackwell
publist_id: '2167'
quality_controlled: 0
status: public
title: MEK signalling tunes actin treadmilling for interstitial lymphocyte migration
type: journal_article
volume: 29
year: '2010'
...
---
_id: '3961'
abstract:
- lang: eng
text: For innate and adaptive immune responses it is essential that inflammatory
cells use quick and flexible locomotion strategies. Accordingly, most leukocytes
can efficiently infiltrate and traverse almost every physiological or artificial
environment. Here, we review how leukocytes might achieve this task mechanistically,
and summarize recent findings on the principles of cytoskeletal force generation
and transduction at the leading edge of leukocytes. We propose a model in which
the cells switch between adhesion-receptor-mediated force transmission and locomotion
modes that are based on cellular deformations, but independent of adhesion receptors.
This plasticity in migration strategies allows leukocytes to adapt to the geometry
and molecular composition of their environment.
acknowledgement: We are grateful to Michele Weber for critical comments on the manuscript.
Work in the laboratory of M.S. is supported by the German Research Foundation, the
Peter Hans Hofschneider Foundation for Experimental Biomedicine and the Max Planck
Society. J.R. is supported by a PhD fellowship of the Böhringer Ingelheim Fond.
We thank Reinhard Fässler and Stefan Jentsch for their continuous support.
author:
- first_name: Jörg
full_name: Jörg Renkawitz
id: 3F0587C8-F248-11E8-B48F-1D18A9856A87
last_name: Renkawitz
orcid: 0000-0003-2856-3369
- first_name: Michael K
full_name: Michael Sixt
id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
last_name: Sixt
orcid: 0000-0002-6620-9179
citation:
ama: Renkawitz J, Sixt MK. Mechanisms of force generation and force transmission
during interstitial leukocyte migration. EMBO Reports. 2010;11(10):744-750.
doi:10.1038/embor.2010.147
apa: Renkawitz, J., & Sixt, M. K. (2010). Mechanisms of force generation and
force transmission during interstitial leukocyte migration. EMBO Reports.
Wiley-Blackwell. https://doi.org/10.1038/embor.2010.147
chicago: Renkawitz, Jörg, and Michael K Sixt. “Mechanisms of Force Generation and
Force Transmission during Interstitial Leukocyte Migration.” EMBO Reports.
Wiley-Blackwell, 2010. https://doi.org/10.1038/embor.2010.147.
ieee: J. Renkawitz and M. K. Sixt, “Mechanisms of force generation and force transmission
during interstitial leukocyte migration,” EMBO Reports, vol. 11, no. 10.
Wiley-Blackwell, pp. 744–750, 2010.
ista: Renkawitz J, Sixt MK. 2010. Mechanisms of force generation and force transmission
during interstitial leukocyte migration. EMBO Reports. 11(10), 744–750.
mla: Renkawitz, Jörg, and Michael K. Sixt. “Mechanisms of Force Generation and Force
Transmission during Interstitial Leukocyte Migration.” EMBO Reports, vol.
11, no. 10, Wiley-Blackwell, 2010, pp. 744–50, doi:10.1038/embor.2010.147.
short: J. Renkawitz, M.K. Sixt, EMBO Reports 11 (2010) 744–750.
date_created: 2018-12-11T12:06:08Z
date_published: 2010-09-24T00:00:00Z
date_updated: 2021-01-12T07:53:30Z
day: '24'
doi: 10.1038/embor.2010.147
extern: 1
intvolume: ' 11'
issue: '10'
month: '09'
page: 744 - 750
publication: EMBO Reports
publication_status: published
publisher: Wiley-Blackwell
publist_id: '2166'
quality_controlled: 0
status: public
title: Mechanisms of force generation and force transmission during interstitial leukocyte
migration
type: journal_article
volume: 11
year: '2010'
...
---
_id: '3962'
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Holger
full_name: Pflicke, Holger
id: CAA57A9A-5B61-11E9-B130-E0C1E1F2C83D
last_name: Pflicke
citation:
ama: Pflicke H. Dendritic cell migration across basement membranes in the skin.
2010.
apa: Pflicke, H. (2010). Dendritic cell migration across basement membranes
in the skin. Institute of Science and Technology Austria.
chicago: Pflicke, Holger. “ Dendritic Cell Migration across Basement Membranes
in the Skin.” Institute of Science and Technology Austria, 2010.
ieee: H. Pflicke, “ Dendritic cell migration across basement membranes in the skin,”
Institute of Science and Technology Austria, 2010.
ista: Pflicke H. 2010. Dendritic cell migration across basement membranes in the
skin. Institute of Science and Technology Austria.
mla: Pflicke, Holger. Dendritic Cell Migration across Basement Membranes in
the Skin. Institute of Science and Technology Austria, 2010.
short: H. Pflicke, Dendritic Cell Migration across Basement Membranes in the Skin,
Institute of Science and Technology Austria, 2010.
date_created: 2018-12-11T12:06:08Z
date_published: 2010-07-01T00:00:00Z
date_updated: 2023-09-07T11:28:47Z
day: '01'
degree_awarded: PhD
department:
- _id: CaHe
- _id: GradSch
language:
- iso: eng
month: '07'
oa_version: None
publication_identifier:
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
publist_id: '2165'
status: public
supervisor:
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
title: "\uFEFF\uFEFFDendritic cell migration across basement membranes in the skin"
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2010'
...
---
_id: '3963'
abstract:
- lang: eng
text: Almost all species of the orchid genus Ophrys are pollinated by sexual deception.
The orchids mimic the sex pheromone of receptive female insects, mainly hymenopterans,
in order to attract males seeking to copulate. Most Ophrys species have achromatic
flowers, but some exhibit a coloured perianth and a bright, conspicuous labellum
pattern. We recently showed that the pink perianth of Ophrys heldreichii flowers
increases detectability by its pollinator, males of the long-horned bee Eucera
berlandi. Here we tested the hypothesis that the bright, complex labellum pattern
mimics the female of the pollinator to increase attractiveness toward males. In
a dual-choice test we offered E. berlandi males an O. heldreichii flower and a
flower from O. dictynnae, which also exhibits a pinkish perianth but no conspicuous
labellum pattern. Both flowers were housed in UV-transmitting acrylic glass boxes
to exclude olfactory signals. Males significantly preferred O. heldreichii to
O. dictynnae flowers. In a second experiment, we replaced the perianth of both
flowers with identical artificial perianths made from pink card, so that only
the labellum differed between the two flower stimuli. Males then chose between
both stimuli at random, suggesting that the presence of a labellum pattern does
not affect their choice. Spectral measurements revealed higher colour contrast
with the background of the perianth of O. heldreichii compared to O. dictynnae,
but no difference in green receptor-specific contrast or brightness. Our results
show that male choice is guided by the chromatic contrast of the perianth during
the initial flower approach but is not affected by the presence of a labellum
pattern. Instead, we hypothesise that the labellum pattern is involved in aversive
learning during post-copulatory behaviour and used by the orchid as a strategy
to increase outcrossing.
article_processing_charge: No
author:
- first_name: M.
full_name: Streinzer, M.
last_name: Streinzer
- first_name: Thomas
full_name: Ellis, Thomas
id: 3153D6D4-F248-11E8-B48F-1D18A9856A87
last_name: Ellis
orcid: 0000-0002-8511-0254
- first_name: H.
full_name: Paulus, H.
last_name: Paulus
- first_name: J.
full_name: Spaethe, J.
last_name: Spaethe
citation:
ama: Streinzer M, Ellis T, Paulus H, Spaethe J. Visual discrimination between two
sexually deceptive Ophrys species by a bee pollinator. Arthropod-Plant Interactions.
2010;4(3):141-148. doi:10.1007/s11829-010-9093-4
apa: Streinzer, M., Ellis, T., Paulus, H., & Spaethe, J. (2010). Visual discrimination
between two sexually deceptive Ophrys species by a bee pollinator. Arthropod-Plant
Interactions. Springer. https://doi.org/10.1007/s11829-010-9093-4
chicago: Streinzer, M., Thomas Ellis, H. Paulus, and J. Spaethe. “Visual Discrimination
between Two Sexually Deceptive Ophrys Species by a Bee Pollinator.” Arthropod-Plant
Interactions. Springer, 2010. https://doi.org/10.1007/s11829-010-9093-4.
ieee: M. Streinzer, T. Ellis, H. Paulus, and J. Spaethe, “Visual discrimination
between two sexually deceptive Ophrys species by a bee pollinator,” Arthropod-Plant
Interactions, vol. 4, no. 3. Springer, pp. 141–148, 2010.
ista: Streinzer M, Ellis T, Paulus H, Spaethe J. 2010. Visual discrimination between
two sexually deceptive Ophrys species by a bee pollinator. Arthropod-Plant Interactions.
4(3), 141–148.
mla: Streinzer, M., et al. “Visual Discrimination between Two Sexually Deceptive
Ophrys Species by a Bee Pollinator.” Arthropod-Plant Interactions, vol.
4, no. 3, Springer, 2010, pp. 141–48, doi:10.1007/s11829-010-9093-4.
short: M. Streinzer, T. Ellis, H. Paulus, J. Spaethe, Arthropod-Plant Interactions
4 (2010) 141–148.
date_created: 2018-12-11T12:06:08Z
date_published: 2010-01-01T00:00:00Z
date_updated: 2021-01-12T07:53:30Z
day: '01'
doi: 10.1007/s11829-010-9093-4
extern: '1'
intvolume: ' 4'
issue: '3'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc/4.0/
month: '01'
oa_version: None
page: 141 - 148
publication: Arthropod-Plant Interactions
publication_status: published
publisher: Springer
publist_id: '2164'
status: public
title: Visual discrimination between two sexually deceptive Ophrys species by a bee
pollinator
tmp:
image: /images/cc_by_nc.png
legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
short: CC BY-NC (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 4
year: '2010'
...
---
_id: '3964'
abstract:
- lang: eng
text: We prove two stability results for Lipschitz functions on triangulable, compact
metric spaces and consider applications of both to problems in systems biology.
Given two functions, the first result is formulated in terms of the Wasserstein
distance between their persistence diagrams and the second in terms of their total
persistence.
acknowledgement: This research is partially supported by the Defense Advanced Research
Projects Agency (DARPA) under grants HR0011-05-1-0007 and HR0011-05-1-0057 and by
CNRS under grant PICS-3416.
author:
- first_name: David
full_name: Cohen-Steiner, David
last_name: Cohen Steiner
- first_name: Herbert
full_name: Herbert Edelsbrunner
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: John
full_name: Harer, John
last_name: Harer
- first_name: Yuriy
full_name: Mileyko, Yuriy
last_name: Mileyko
citation:
ama: Cohen Steiner D, Edelsbrunner H, Harer J, Mileyko Y. Lipschitz functions have
L_p-stable persistence. Foundations of Computational Mathematics. 2010;10(2):127-139.
doi:10.1007/s10208-010-9060-6
apa: Cohen Steiner, D., Edelsbrunner, H., Harer, J., & Mileyko, Y. (2010). Lipschitz
functions have L_p-stable persistence. Foundations of Computational Mathematics.
Springer. https://doi.org/10.1007/s10208-010-9060-6
chicago: Cohen Steiner, David, Herbert Edelsbrunner, John Harer, and Yuriy Mileyko.
“Lipschitz Functions Have L_p-Stable Persistence.” Foundations of Computational
Mathematics. Springer, 2010. https://doi.org/10.1007/s10208-010-9060-6.
ieee: D. Cohen Steiner, H. Edelsbrunner, J. Harer, and Y. Mileyko, “Lipschitz functions
have L_p-stable persistence,” Foundations of Computational Mathematics,
vol. 10, no. 2. Springer, pp. 127–139, 2010.
ista: Cohen Steiner D, Edelsbrunner H, Harer J, Mileyko Y. 2010. Lipschitz functions
have L_p-stable persistence. Foundations of Computational Mathematics. 10(2),
127–139.
mla: Cohen Steiner, David, et al. “Lipschitz Functions Have L_p-Stable Persistence.”
Foundations of Computational Mathematics, vol. 10, no. 2, Springer, 2010,
pp. 127–39, doi:10.1007/s10208-010-9060-6.
short: D. Cohen Steiner, H. Edelsbrunner, J. Harer, Y. Mileyko, Foundations of Computational
Mathematics 10 (2010) 127–139.
date_created: 2018-12-11T12:06:09Z
date_published: 2010-01-28T00:00:00Z
date_updated: 2021-01-12T07:53:31Z
day: '28'
doi: 10.1007/s10208-010-9060-6
extern: 1
intvolume: ' 10'
issue: '2'
month: '01'
page: 127 - 139
publication: Foundations of Computational Mathematics
publication_status: published
publisher: Springer
publist_id: '2163'
quality_controlled: 0
status: public
title: Lipschitz functions have L_p-stable persistence
type: journal_article
volume: 10
year: '2010'
...
---
_id: '4134'
abstract:
- lang: eng
text: 'All species are restricted in their distribution. Currently, ecological models
can only explain such limits if patches vary in quality, leading to asymmetrical
dispersal, or if genetic variation is too low at the margins for adaptation. However,
population genetic models suggest that the increase in genetic variance resulting
from dispersal should allow adaptation to almost any ecological gradient. Clearly
therefore, these models miss something that prevents evolution in natural populations.
We developed an individual-based simulation to explore stochastic effects in these
models. At high carrying capacities, our simulations largely agree with deterministic
predictions. However, when carrying capacity is low, the population fails to establish
for a wide range of parameter values where adaptation was expected from previous
models. Stochastic or transient effects appear critical around the boundaries
in parameter space between simulation behaviours. Dispersal, gradient steepness,
and population density emerge as key factors determining adaptation on an ecological
gradient. '
acknowledgement: We are very grateful to Nick Barton.
author:
- first_name: Jon
full_name: Bridle, Jon
last_name: Bridle
- first_name: Jitka
full_name: Polechova, Jitka
id: 3BBFB084-F248-11E8-B48F-1D18A9856A87
last_name: Polechova
orcid: 0000-0003-0951-3112
- first_name: Masakado
full_name: Kawata, Masakado
last_name: Kawata
- first_name: Roger
full_name: Butlin, Roger
last_name: Butlin
citation:
ama: Bridle J, Polechova J, Kawata M, Butlin R. Why is adaptation prevented at ecological
margins? New insights from individual-based simulations. Ecology Letters.
2010;13(4):485-494. doi:10.1111/j.1461-0248.2010.01442.x
apa: Bridle, J., Polechova, J., Kawata, M., & Butlin, R. (2010). Why is adaptation
prevented at ecological margins? New insights from individual-based simulations.
Ecology Letters. Wiley-Blackwell. https://doi.org/10.1111/j.1461-0248.2010.01442.x
chicago: Bridle, Jon, Jitka Polechova, Masakado Kawata, and Roger Butlin. “Why Is
Adaptation Prevented at Ecological Margins? New Insights from Individual-Based
Simulations.” Ecology Letters. Wiley-Blackwell, 2010. https://doi.org/10.1111/j.1461-0248.2010.01442.x.
ieee: J. Bridle, J. Polechova, M. Kawata, and R. Butlin, “Why is adaptation prevented
at ecological margins? New insights from individual-based simulations,” Ecology
Letters, vol. 13, no. 4. Wiley-Blackwell, pp. 485–494, 2010.
ista: Bridle J, Polechova J, Kawata M, Butlin R. 2010. Why is adaptation prevented
at ecological margins? New insights from individual-based simulations. Ecology
Letters. 13(4), 485–494.
mla: Bridle, Jon, et al. “Why Is Adaptation Prevented at Ecological Margins? New
Insights from Individual-Based Simulations.” Ecology Letters, vol. 13,
no. 4, Wiley-Blackwell, 2010, pp. 485–94, doi:10.1111/j.1461-0248.2010.01442.x.
short: J. Bridle, J. Polechova, M. Kawata, R. Butlin, Ecology Letters 13 (2010)
485–494.
date_created: 2018-12-11T12:07:08Z
date_published: 2010-03-15T00:00:00Z
date_updated: 2021-01-12T07:54:45Z
day: '15'
department:
- _id: NiBa
doi: 10.1111/j.1461-0248.2010.01442.x
ec_funded: 1
intvolume: ' 13'
issue: '4'
language:
- iso: eng
month: '03'
oa_version: None
page: 485 - 494
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: Ecology Letters
publication_status: published
publisher: Wiley-Blackwell
publist_id: '1987'
quality_controlled: '1'
scopus_import: 1
status: public
title: Why is adaptation prevented at ecological margins? New insights from individual-based
simulations
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 13
year: '2010'
...
---
_id: '4157'
abstract:
- lang: eng
text: Integrin- and cadherin-mediated adhesion is central for cell and tissue morphogenesis,
allowing cells and tissues to change shape without loosing integrity. Studies
predominantly in cell culture showed that mechanosensation through adhesion structures
is achieved by force-mediated modulation of their molecular composition. The specific
molecular composition of adhesion sites in turn determines their signalling activity
and dynamic reorganization. Here, we will review how adhesion sites respond to
mecanical stimuli, and how spatially and temporally regulated signalling from
different adhesion sites controls cell migration and tissue morphogenesis.
acknowledged_ssus:
- _id: Bio
author:
- first_name: Ekaterina
full_name: Papusheva, Ekaterina
id: 41DB591E-F248-11E8-B48F-1D18A9856A87
last_name: Papusheva
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: 'Papusheva E, Heisenberg C-PJ. Spatial organization of adhesion: force-dependent
regulation and function in tissue morphogenesis. EMBO Journal. 2010;29(16):2753-2768.
doi:10.1038/emboj.2010.182'
apa: 'Papusheva, E., & Heisenberg, C.-P. J. (2010). Spatial organization of
adhesion: force-dependent regulation and function in tissue morphogenesis. EMBO
Journal. Wiley-Blackwell. https://doi.org/10.1038/emboj.2010.182'
chicago: 'Papusheva, Ekaterina, and Carl-Philipp J Heisenberg. “Spatial Organization
of Adhesion: Force-Dependent Regulation and Function in Tissue Morphogenesis.”
EMBO Journal. Wiley-Blackwell, 2010. https://doi.org/10.1038/emboj.2010.182.'
ieee: 'E. Papusheva and C.-P. J. Heisenberg, “Spatial organization of adhesion:
force-dependent regulation and function in tissue morphogenesis,” EMBO Journal,
vol. 29, no. 16. Wiley-Blackwell, pp. 2753–2768, 2010.'
ista: 'Papusheva E, Heisenberg C-PJ. 2010. Spatial organization of adhesion: force-dependent
regulation and function in tissue morphogenesis. EMBO Journal. 29(16), 2753–2768.'
mla: 'Papusheva, Ekaterina, and Carl-Philipp J. Heisenberg. “Spatial Organization
of Adhesion: Force-Dependent Regulation and Function in Tissue Morphogenesis.”
EMBO Journal, vol. 29, no. 16, Wiley-Blackwell, 2010, pp. 2753–68, doi:10.1038/emboj.2010.182.'
short: E. Papusheva, C.-P.J. Heisenberg, EMBO Journal 29 (2010) 2753–2768.
date_created: 2018-12-11T12:07:17Z
date_published: 2010-08-18T00:00:00Z
date_updated: 2021-01-12T07:54:55Z
day: '18'
department:
- _id: Bio
- _id: CaHe
doi: 10.1038/emboj.2010.182
external_id:
pmid:
- '20717145'
intvolume: ' 29'
issue: '16'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924654/
month: '08'
oa: 1
oa_version: Submitted Version
page: 2753 - 2768
pmid: 1
publication: EMBO Journal
publication_status: published
publisher: Wiley-Blackwell
publist_id: '1962'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'Spatial organization of adhesion: force-dependent regulation and function
in tissue morphogenesis'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 29
year: '2010'
...
---
_id: '4163'
abstract:
- lang: eng
text: Organ formation requires the precise assembly of progenitor cells into a functional
multicellular structure. Mechanical forces probably participate in this process
but how they influence organ morphogenesis is still unclear. Here, we show that
Wnt11- and Prickle1a-mediated planar cell polarity (PCP) signalling coordinates
the formation of the zebrafish ciliated laterality organ (Kupffer's vesicle) by
regulating adhesion properties between organ progenitor cells (the dorsal forerunner
cells, DFCs). Combined inhibition of Wnt11 and Prickle1a reduces DFC cell-cell
adhesion and impairs their compaction and arrangement during vesicle lumen formation.
This leads to the formation of a mis-shapen vesicle with small fragmented lumina
and shortened cilia, resulting in severely impaired organ function and, as a consequence,
randomised laterality of both molecular and visceral asymmetries. Our results
reveal a novel role for PCP-dependent cell adhesion in coordinating the supracellular
organisation of progenitor cells during vertebrate laterality organ formation.
article_processing_charge: No
author:
- first_name: Pablo
full_name: Oteíza, Pablo
last_name: Oteíza
- first_name: Mathias
full_name: Koeppen, Mathias
last_name: Koeppen
- first_name: Michael
full_name: Krieg, Michael
last_name: Krieg
- first_name: Eduardo
full_name: Pulgar, Eduardo
last_name: Pulgar
- first_name: Cecilia
full_name: Farias, Cecilia
last_name: Farias
- first_name: Cristina
full_name: Melo, Cristina
last_name: Melo
- first_name: Steffen
full_name: Preibisch, Steffen
last_name: Preibisch
- first_name: Daniel
full_name: Mueller, Daniel
last_name: Mueller
- first_name: Masazumi
full_name: Tada, Masazumi
last_name: Tada
- first_name: Steffen
full_name: Hartel, Steffen
last_name: Hartel
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
- first_name: Miguel
full_name: Concha, Miguel
last_name: Concha
citation:
ama: Oteíza P, Koeppen M, Krieg M, et al. Planar cell polarity signalling regulates
cell adhesion properties in progenitors of the zebrafish laterality organ. Development.
2010;137(20):3459-3468. doi:10.1242/dev.049981
apa: Oteíza, P., Koeppen, M., Krieg, M., Pulgar, E., Farias, C., Melo, C., … Concha,
M. (2010). Planar cell polarity signalling regulates cell adhesion properties
in progenitors of the zebrafish laterality organ. Development. Company
of Biologists. https://doi.org/10.1242/dev.049981
chicago: Oteíza, Pablo, Mathias Koeppen, Michael Krieg, Eduardo Pulgar, Cecilia
Farias, Cristina Melo, Steffen Preibisch, et al. “Planar Cell Polarity Signalling
Regulates Cell Adhesion Properties in Progenitors of the Zebrafish Laterality
Organ.” Development. Company of Biologists, 2010. https://doi.org/10.1242/dev.049981.
ieee: P. Oteíza et al., “Planar cell polarity signalling regulates cell adhesion
properties in progenitors of the zebrafish laterality organ,” Development,
vol. 137, no. 20. Company of Biologists, pp. 3459–3468, 2010.
ista: Oteíza P, Koeppen M, Krieg M, Pulgar E, Farias C, Melo C, Preibisch S, Mueller
D, Tada M, Hartel S, Heisenberg C-PJ, Concha M. 2010. Planar cell polarity signalling
regulates cell adhesion properties in progenitors of the zebrafish laterality
organ. Development. 137(20), 3459–3468.
mla: Oteíza, Pablo, et al. “Planar Cell Polarity Signalling Regulates Cell Adhesion
Properties in Progenitors of the Zebrafish Laterality Organ.” Development,
vol. 137, no. 20, Company of Biologists, 2010, pp. 3459–68, doi:10.1242/dev.049981.
short: P. Oteíza, M. Koeppen, M. Krieg, E. Pulgar, C. Farias, C. Melo, S. Preibisch,
D. Mueller, M. Tada, S. Hartel, C.-P.J. Heisenberg, M. Concha, Development 137
(2010) 3459–3468.
date_created: 2018-12-11T12:07:20Z
date_published: 2010-10-15T00:00:00Z
date_updated: 2021-01-12T07:54:58Z
day: '15'
doi: 10.1242/dev.049981
extern: '1'
intvolume: ' 137'
issue: '20'
language:
- iso: eng
month: '10'
oa_version: None
page: 3459 - 3468
publication: Development
publication_status: published
publisher: Company of Biologists
publist_id: '1958'
status: public
title: Planar cell polarity signalling regulates cell adhesion properties in progenitors
of the zebrafish laterality organ
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 137
year: '2010'
...
---
_id: '4187'
abstract:
- lang: eng
text: Cell migration is central to embryonic development, homeostasis and disease(1),
processes in which cells move as part of a group or individually. Whereas the
mechanisms controlling single-cell migration in vitro are relatively well understood(2-4),
less is known about the mechanisms promoting the motility of individual cells
in vivo. In particular, it is not clear how cells that form blebs in their migration
use those protrusions to bring about movement in the context of the three-dimensional
cellular environment(5,6). Here we show that the motility of chemokine-guided
germ cells within the zebrafish embryo requires the function of the small Rho
GTPases Rac1 and RhoA, as well as E-cadherin-mediated cell-cell adhesion. Using
fluorescence resonance energy transfer we demonstrate that Rac1 and RhoA are activated
in the cell front. At this location, Rac1 is responsible for the formation of
actin-rich structures, and RhoA promotes retrograde actin flow. We propose that
these actin-rich structures undergoing retrograde flow are essential for the generation
of E-cadherin-mediated traction forces between the germ cells and the surrounding
tissue and are therefore crucial for cell motility in vivo.
author:
- first_name: Elena
full_name: Kardash, Elena
last_name: Kardash
- first_name: Michal
full_name: Reichman-Fried, Michal
last_name: Reichman Fried
- first_name: Jean
full_name: Maître, Jean-Léon
last_name: Maître
- first_name: Bijan
full_name: Boldajipour, Bijan
last_name: Boldajipour
- first_name: Ekaterina
full_name: Ekaterina Papusheva
id: 41DB591E-F248-11E8-B48F-1D18A9856A87
last_name: Papusheva
- first_name: Esther
full_name: Messerschmidt, Esther-Maria
last_name: Messerschmidt
- first_name: Carl
full_name: Heisenberg, Carl-Philipp
last_name: Heisenberg
- first_name: Erez
full_name: Raz, Erez
last_name: Raz
citation:
ama: Kardash E, Reichman Fried M, Maître J, et al. A role for Rho GTPases and cell-cell
adhesion in single-cell motility in vivo. Nature Cell Biology. 2010;12(1):47-53.
doi:10.1038/ncb2003
apa: Kardash, E., Reichman Fried, M., Maître, J., Boldajipour, B., Papusheva, E.,
Messerschmidt, E., … Raz, E. (2010). A role for Rho GTPases and cell-cell adhesion
in single-cell motility in vivo. Nature Cell Biology. Nature Publishing
Group. https://doi.org/10.1038/ncb2003
chicago: Kardash, Elena, Michal Reichman Fried, Jean Maître, Bijan Boldajipour,
Ekaterina Papusheva, Esther Messerschmidt, Carl Heisenberg, and Erez Raz. “A Role
for Rho GTPases and Cell-Cell Adhesion in Single-Cell Motility in Vivo.” Nature
Cell Biology. Nature Publishing Group, 2010. https://doi.org/10.1038/ncb2003.
ieee: E. Kardash et al., “A role for Rho GTPases and cell-cell adhesion in
single-cell motility in vivo,” Nature Cell Biology, vol. 12, no. 1. Nature
Publishing Group, pp. 47–53, 2010.
ista: Kardash E, Reichman Fried M, Maître J, Boldajipour B, Papusheva E, Messerschmidt
E, Heisenberg C, Raz E. 2010. A role for Rho GTPases and cell-cell adhesion in
single-cell motility in vivo. Nature Cell Biology. 12(1), 47–53.
mla: Kardash, Elena, et al. “A Role for Rho GTPases and Cell-Cell Adhesion in Single-Cell
Motility in Vivo.” Nature Cell Biology, vol. 12, no. 1, Nature Publishing
Group, 2010, pp. 47–53, doi:10.1038/ncb2003.
short: E. Kardash, M. Reichman Fried, J. Maître, B. Boldajipour, E. Papusheva, E.
Messerschmidt, C. Heisenberg, E. Raz, Nature Cell Biology 12 (2010) 47–53.
date_created: 2018-12-11T12:07:28Z
date_published: 2010-01-01T00:00:00Z
date_updated: 2021-01-12T07:55:09Z
day: '01'
doi: 10.1038/ncb2003
extern: 1
intvolume: ' 12'
issue: '1'
month: '01'
page: 47 - 53
publication: Nature Cell Biology
publication_status: published
publisher: Nature Publishing Group
publist_id: '1932'
quality_controlled: 0
status: public
title: A role for Rho GTPases and cell-cell adhesion in single-cell motility in vivo
type: journal_article
volume: 12
year: '2010'
...
---
_id: '4221'
abstract:
- lang: eng
text: Collective cell migration, the simultaneous movement of multiple cells that
are connected by cell-cell adhesion, is ubiquitous in development, tissue repair,
and tumor metastasis [1, 2]. It has been hypothesized that the directionality
of cell movement during collective migration emerges as a collective property
[3, 4]. Here we determine how movement directionality is established in collective
mesendoderm migration during zebrafish gastrulation. By interfering with two key
features of collective migration, (1) having neighboring cells and (2) adhering
to them, we show that individual mesendoderm cells are capable of normal directed
migration when moving as single cells but require cell-cell adhesion to participate
in coordinated and directed migration when moving as part of a group. We conclude
that movement directionality is not a de novo collective property of mesendoderm
cells but rather a property of single mesendoderm cells that requires cell-cell
adhesion during collective migration.
article_processing_charge: No
author:
- first_name: Yohanna
full_name: Arboleda Estudillo, Yohanna
last_name: Arboleda Estudillo
- first_name: Michael
full_name: Krieg, Michael
last_name: Krieg
- first_name: Jan
full_name: Stuehmer, Jan
last_name: Stuehmer
- first_name: Nicholas
full_name: Licata, Nicholas
last_name: Licata
- first_name: Daniel
full_name: Mueller, Daniel
last_name: Mueller
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Arboleda Estudillo Y, Krieg M, Stuehmer J, Licata N, Mueller D, Heisenberg
C-PJ. Movement directionality in collective migration of germ layer progenitors.
Current Biology. 2010;20(2):161-169. doi:10.1016/j.cub.2009.11.036
apa: Arboleda Estudillo, Y., Krieg, M., Stuehmer, J., Licata, N., Mueller, D., &
Heisenberg, C.-P. J. (2010). Movement directionality in collective migration of
germ layer progenitors. Current Biology. Cell Press. https://doi.org/10.1016/j.cub.2009.11.036
chicago: Arboleda Estudillo, Yohanna, Michael Krieg, Jan Stuehmer, Nicholas Licata,
Daniel Mueller, and Carl-Philipp J Heisenberg. “Movement Directionality in Collective
Migration of Germ Layer Progenitors.” Current Biology. Cell Press, 2010.
https://doi.org/10.1016/j.cub.2009.11.036.
ieee: Y. Arboleda Estudillo, M. Krieg, J. Stuehmer, N. Licata, D. Mueller, and C.-P.
J. Heisenberg, “Movement directionality in collective migration of germ layer
progenitors,” Current Biology, vol. 20, no. 2. Cell Press, pp. 161–169,
2010.
ista: Arboleda Estudillo Y, Krieg M, Stuehmer J, Licata N, Mueller D, Heisenberg
C-PJ. 2010. Movement directionality in collective migration of germ layer progenitors.
Current Biology. 20(2), 161–169.
mla: Arboleda Estudillo, Yohanna, et al. “Movement Directionality in Collective
Migration of Germ Layer Progenitors.” Current Biology, vol. 20, no. 2,
Cell Press, 2010, pp. 161–69, doi:10.1016/j.cub.2009.11.036.
short: Y. Arboleda Estudillo, M. Krieg, J. Stuehmer, N. Licata, D. Mueller, C.-P.J.
Heisenberg, Current Biology 20 (2010) 161–169.
date_created: 2018-12-11T12:07:40Z
date_published: 2010-01-26T00:00:00Z
date_updated: 2021-01-12T07:55:25Z
day: '26'
doi: 10.1016/j.cub.2009.11.036
extern: '1'
intvolume: ' 20'
issue: '2'
language:
- iso: eng
month: '01'
oa_version: None
page: 161 - 169
publication: Current Biology
publication_status: published
publisher: Cell Press
publist_id: '1897'
status: public
title: Movement directionality in collective migration of germ layer progenitors
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 20
year: '2010'
...
---
_id: '4243'
abstract:
- lang: eng
text: We investigate a new model for populations evolving in a spatial continuum.
This model can be thought of as a spatial version of the Lambda-Fleming-Viot process.
It explicitly incorporates both small scale reproduction events and large scale
extinction-recolonisation events. The lineages ancestral to a sample from a population
evolving according to this model can be described in terms of a spatial version
of the Lambda-coalescent. Using a technique of Evans (1997), we prove existence
and uniqueness in law for the model. We then investigate the asymptotic behaviour
of the genealogy of a finite number of individuals sampled uniformly at random
(or more generally `far enough apart') from a two-dimensional torus of sidelength
L as L tends to infinity. Under appropriate conditions (and on a suitable timescale)
we can obtain as limiting genealogical processes a Kingman coalescent, a more
general Lambda-coalescent or a system of coalescing Brownian motions (with a non-local
coalescence mechanism).
author:
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: Alison
full_name: Etheridge, Alison
last_name: Etheridge
- first_name: Amandine
full_name: Véber, Amandine
last_name: Véber
citation:
ama: Barton NH, Etheridge A, Véber A. A new model for evolution in a spatial continuum.
Electronic Journal of Probability. 2010;15(7):162-216. doi:10.1214/EJP.v15-741
apa: Barton, N. H., Etheridge, A., & Véber, A. (2010). A new model for evolution
in a spatial continuum. Electronic Journal of Probability. Institute of
Mathematical Statistics. https://doi.org/10.1214/EJP.v15-741
chicago: Barton, Nicholas H, Alison Etheridge, and Amandine Véber. “A New Model
for Evolution in a Spatial Continuum.” Electronic Journal of Probability.
Institute of Mathematical Statistics, 2010. https://doi.org/10.1214/EJP.v15-741.
ieee: N. H. Barton, A. Etheridge, and A. Véber, “A new model for evolution in a
spatial continuum,” Electronic Journal of Probability, vol. 15, no. 7.
Institute of Mathematical Statistics, pp. 162–216, 2010.
ista: Barton NH, Etheridge A, Véber A. 2010. A new model for evolution in a spatial
continuum. Electronic Journal of Probability. 15(7), 162–216.
mla: Barton, Nicholas H., et al. “A New Model for Evolution in a Spatial Continuum.”
Electronic Journal of Probability, vol. 15, no. 7, Institute of Mathematical
Statistics, 2010, pp. 162–216, doi:10.1214/EJP.v15-741.
short: N.H. Barton, A. Etheridge, A. Véber, Electronic Journal of Probability 15
(2010) 162–216.
date_created: 2018-12-11T12:07:48Z
date_published: 2010-02-03T00:00:00Z
date_updated: 2021-01-12T07:55:34Z
day: '03'
ddc:
- '576'
department:
- _id: NiBa
doi: 10.1214/EJP.v15-741
file:
- access_level: open_access
checksum: bab577546dd4e8f882e9a9dd645cd01e
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:15:21Z
date_updated: 2020-07-14T12:46:26Z
file_id: '5140'
file_name: IST-2015-369-v1+1_741-2535-1-PB.pdf
file_size: 450171
relation: main_file
file_date_updated: 2020-07-14T12:46:26Z
has_accepted_license: '1'
intvolume: ' 15'
issue: '7'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '02'
oa: 1
oa_version: Published Version
page: 162 - 216
publication: Electronic Journal of Probability
publication_status: published
publisher: Institute of Mathematical Statistics
publist_id: '1863'
pubrep_id: '369'
quality_controlled: '1'
scopus_import: 1
status: public
title: A new model for evolution in a spatial continuum
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 15
year: '2010'
...
---
_id: '4339'
abstract:
- lang: ger
text: Mit diesem Buch möchten wir einen Überblick der aktuellen Diskussion zum Thema
Bibliothek 2.0 geben und den Stand der tatsächlichen Umsetzung der Web 2.0-Ansätze
in deutschsprachigen Bibliotheken beleuchten. An dieser Stelle ist die Frage erlaubt,
warum es zu einer Zeit, in der es bereits die ersten "Web 3.0"- Konferenzen gibt,
eines Handbuches der Bibliothek 2.0 noch bedarf. Und warum es überhaupt ein deutschsprachiges
Handbuch zur Bibliothek 2.0 braucht, wo es doch bereits verschiedenste Publikationen
zu diesem Thema aus anderen Ländern, insbesondere des angloamerikanischen Raums
gibt. Ist dazu nicht bereits alles gesagt?
author:
- first_name: Julia
full_name: Bergmann, Julia
last_name: Bergmann
- first_name: Patrick
full_name: Danowski, Patrick
id: 2EBD1598-F248-11E8-B48F-1D18A9856A87
last_name: Danowski
orcid: 0000-0002-6026-4409
citation:
ama: 'Bergmann J, Danowski P. Ist Bibliothek 2.0 überhaupt noch relevant? – Eine
Einleitung in das Handbuch. In: Bergmann J, Danowski P, eds. Handbuch Bibliothek
2.0. Bibliotheks- und Informationspraxis 41. De Gruyter; 2010:5-20. doi:10.1515/9783110232103'
apa: Bergmann, J., & Danowski, P. (2010). Ist Bibliothek 2.0 überhaupt noch
relevant? – Eine Einleitung in das Handbuch. In J. Bergmann & P. Danowski
(Eds.), Handbuch Bibliothek 2.0 (pp. 5–20). De Gruyter. https://doi.org/10.1515/9783110232103
chicago: Bergmann, Julia, and Patrick Danowski. “Ist Bibliothek 2.0 Überhaupt Noch
Relevant? – Eine Einleitung in Das Handbuch.” In Handbuch Bibliothek 2.0,
edited by Julia Bergmann and Patrick Danowski, 5–20. Bibliotheks- Und Informationspraxis
41. De Gruyter, 2010. https://doi.org/10.1515/9783110232103.
ieee: J. Bergmann and P. Danowski, “Ist Bibliothek 2.0 überhaupt noch relevant?
– Eine Einleitung in das Handbuch,” in Handbuch Bibliothek 2.0, J. Bergmann
and P. Danowski, Eds. De Gruyter, 2010, pp. 5–20.
ista: 'Bergmann J, Danowski P. 2010.Ist Bibliothek 2.0 überhaupt noch relevant?
– Eine Einleitung in das Handbuch. In: Handbuch Bibliothek 2.0. , 5–20.'
mla: Bergmann, Julia, and Patrick Danowski. “Ist Bibliothek 2.0 Überhaupt Noch Relevant?
– Eine Einleitung in Das Handbuch.” Handbuch Bibliothek 2.0, edited by
Julia Bergmann and Patrick Danowski, De Gruyter, 2010, pp. 5–20, doi:10.1515/9783110232103.
short: J. Bergmann, P. Danowski, in:, J. Bergmann, P. Danowski (Eds.), Handbuch
Bibliothek 2.0, De Gruyter, 2010, pp. 5–20.
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