---
_id: '3773'
abstract:
- lang: eng
text: If distinct biological species are to coexist in sympatry, they must be reproductively
isolated and must exploit different limiting resources. A two-niche Levene model
is analysed, in which habitat preference and survival depend on underlying additive
traits. The population genetics of preference and viability are equivalent. However,
there is a linear trade-off between the chances of settling in either niche, whereas
viabilities may be constrained arbitrarily. With a convex trade-off, a sexual
population evolves a single generalist genotype, whereas with a concave trade-off,
disruptive selection favours maximal variance. A pure habitat preference evolves
to global linkage equilibrium if mating occurs in a single pool, but remarkably,
evolves to pairwise linkage equilibrium within niches if mating is within those
niches--independent of the genetics. With a concave trade-off, the population
shifts sharply between a unimodal distribution with high gene flow and a bimodal
distribution with strong isolation, as the underlying genetic variance increases.
However, these alternative states are only simultaneously stable for a narrow
parameter range. A sharp threshold is only seen if survival in the 'wrong' niche
is low; otherwise, strong isolation is impossible. Gene flow from divergent demes
makes speciation much easier in parapatry than in sympatry.
acknowledgement: "The author thanks the Werner-Gren Foundation and the Royal Swedish
Academy of Sciences for organizing the symposium on the ‘Origin of Species’. He
also thanks Reinhard Bürger, and two anonymous referees, for their helpful comments.\r\n"
author:
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: Barton NH. What role does natural selection play in speciation? Philosophical
Transactions of the Royal Society of London Series B, Biological Sciences.
2010;365(1547):1825-1840. doi:10.1098/rstb.2010.0001
apa: Barton, N. H. (2010). What role does natural selection play in speciation?
Philosophical Transactions of the Royal Society of London. Series B, Biological
Sciences. Royal Society. https://doi.org/10.1098/rstb.2010.0001
chicago: Barton, Nicholas H. “What Role Does Natural Selection Play in Speciation?”
Philosophical Transactions of the Royal Society of London. Series B, Biological
Sciences. Royal Society, 2010. https://doi.org/10.1098/rstb.2010.0001.
ieee: N. H. Barton, “What role does natural selection play in speciation?,” Philosophical
Transactions of the Royal Society of London. Series B, Biological Sciences,
vol. 365, no. 1547. Royal Society, pp. 1825–1840, 2010.
ista: Barton NH. 2010. What role does natural selection play in speciation? Philosophical
Transactions of the Royal Society of London. Series B, Biological Sciences. 365(1547),
1825–1840.
mla: Barton, Nicholas H. “What Role Does Natural Selection Play in Speciation?”
Philosophical Transactions of the Royal Society of London. Series B, Biological
Sciences, vol. 365, no. 1547, Royal Society, 2010, pp. 1825–40, doi:10.1098/rstb.2010.0001.
short: N.H. Barton, Philosophical Transactions of the Royal Society of London. Series
B, Biological Sciences 365 (2010) 1825–1840.
date_created: 2018-12-11T12:05:05Z
date_published: 2010-06-12T00:00:00Z
date_updated: 2021-01-12T07:52:06Z
day: '12'
department:
- _id: NiBa
doi: 10.1098/rstb.2010.0001
external_id:
pmid:
- '20439284'
intvolume: ' 365'
issue: '1547'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pubmed/20439284
month: '06'
oa: 1
oa_version: Submitted Version
page: 1825 - 1840
pmid: 1
publication: Philosophical Transactions of the Royal Society of London. Series B,
Biological Sciences
publication_status: published
publisher: Royal Society
publist_id: '2455'
quality_controlled: '1'
scopus_import: 1
status: public
title: What role does natural selection play in speciation?
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 365
year: '2010'
...
---
_id: '3774'
abstract:
- lang: eng
text: 1. Hybridisation with an invasive species has the potential to alter the phenotype
and hence the ecology of a native counterpart. 2. Here data from populations of
native red deer Cervus elaphus and invasive sika deer Cervus nippon in Scotland
is used to assess the extent to which hybridisation between them is causing phenotypic
change. This is done by regression of phenotypic traits against genetic hybrid
scores. 3. Hybridisation is causing increases in the body weight of sika-like
deer and decreases in the body weight of red-like females. Hybridisation is causing
increases in jaw length and increases in incisor arcade breadth in sika-like females.
Hybridisation is also causing decreases in incisor arcade breadth in red-like
females. 4. There is currently no evidence that hybridisation is causing changes
in the kidney fat weight or pregnancy rates of either population. 5. Increased
phenotypic similarity between the two species is likely to lead to further hybridisation.
The ecological consequences of this are difficult to predict.
acknowledgement: "This project was funded through a NERC studentship to HVS which
was CASE partnered by the Macaulay Institute.\r\nWe thank the Forestry Commission
Scotland rangers for all their help with providing the larder data for and samples
from red and sika deer, Stephen Senn and Jarrod Hadfield for statistical advice
and Steve Albon for helpful comments on the manuscript."
author:
- first_name: Helen
full_name: Senn, Helen
last_name: Senn
- first_name: Graeme
full_name: Swanson, Graeme
last_name: Swanson
- first_name: Simon
full_name: Goodman, Simon
last_name: Goodman
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: Josephine
full_name: Pemberton, Josephine
last_name: Pemberton
citation:
ama: Senn H, Swanson G, Goodman S, Barton NH, Pemberton J. Phenotypic correlates
of hybridisation between red and sika deer (genus Cervus). Journal of Animal
Ecology. 2010;79(2):414-425. doi:10.1111/j.1365-2656.2009.01633.x
apa: Senn, H., Swanson, G., Goodman, S., Barton, N. H., & Pemberton, J. (2010).
Phenotypic correlates of hybridisation between red and sika deer (genus Cervus).
Journal of Animal Ecology. Wiley-Blackwell. https://doi.org/10.1111/j.1365-2656.2009.01633.x
chicago: Senn, Helen, Graeme Swanson, Simon Goodman, Nicholas H Barton, and Josephine
Pemberton. “Phenotypic Correlates of Hybridisation between Red and Sika Deer (Genus
Cervus).” Journal of Animal Ecology. Wiley-Blackwell, 2010. https://doi.org/10.1111/j.1365-2656.2009.01633.x.
ieee: H. Senn, G. Swanson, S. Goodman, N. H. Barton, and J. Pemberton, “Phenotypic
correlates of hybridisation between red and sika deer (genus Cervus),” Journal
of Animal Ecology, vol. 79, no. 2. Wiley-Blackwell, pp. 414–425, 2010.
ista: Senn H, Swanson G, Goodman S, Barton NH, Pemberton J. 2010. Phenotypic correlates
of hybridisation between red and sika deer (genus Cervus). Journal of Animal Ecology.
79(2), 414–425.
mla: Senn, Helen, et al. “Phenotypic Correlates of Hybridisation between Red and
Sika Deer (Genus Cervus).” Journal of Animal Ecology, vol. 79, no. 2, Wiley-Blackwell,
2010, pp. 414–25, doi:10.1111/j.1365-2656.2009.01633.x.
short: H. Senn, G. Swanson, S. Goodman, N.H. Barton, J. Pemberton, Journal of Animal
Ecology 79 (2010) 414–425.
date_created: 2018-12-11T12:05:06Z
date_published: 2010-03-01T00:00:00Z
date_updated: 2021-01-12T07:52:06Z
day: '01'
department:
- _id: NiBa
doi: 10.1111/j.1365-2656.2009.01633.x
external_id:
pmid:
- '20002231'
intvolume: ' 79'
issue: '2'
language:
- iso: eng
month: '03'
oa_version: None
page: 414 - 425
pmid: 1
publication: Journal of Animal Ecology
publication_status: published
publisher: Wiley-Blackwell
publist_id: '2453'
quality_controlled: '1'
scopus_import: 1
status: public
title: Phenotypic correlates of hybridisation between red and sika deer (genus Cervus)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 79
year: '2010'
...
---
_id: '3776'
abstract:
- lang: eng
text: 'The prevalence of recombination in eukaryotes poses one of the most puzzling
questions in biology. The most compelling general explanation is that recombination
facilitates selection by breaking down the negative associations generated by
random drift (i.e. Hill-Robertson interference, HRI). I classify the effects of
HRI owing to: deleterious mutation, balancing selection and selective sweeps on:
neutral diversity, rates of adaptation and the mutation load. These effects are
mediated primarily by the density of deleterious mutations and of selective sweeps.
Sequence polymorphism and divergence suggest that these rates may be high enough
to cause significant interference even in genomic regions of high recombination.
However, neither seems able to generate enough variance in fitness to select strongly
for high rates of recombination. It is plausible that spatial and temporal fluctuations
in selection generate much more fitness variance, and hence selection for recombination,
than can be explained by uniformly deleterious mutations or species-wide selective
sweeps.'
acknowledgement: "Royal Society and Wolfson Foundation for their support\r\nWe would
like to thank Brian Charlesworth and Sally Otto for their helpful comments."
author:
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: Barton NH. Genetic linkage and natural selection. Philosophical Transactions
of the Royal Society of London Series B, Biological Sciences. 2010;365(1552):2559-2569.
doi:10.1098/rstb.2010.0106
apa: Barton, N. H. (2010). Genetic linkage and natural selection. Philosophical
Transactions of the Royal Society of London. Series B, Biological Sciences.
Royal Society. https://doi.org/10.1098/rstb.2010.0106
chicago: Barton, Nicholas H. “Genetic Linkage and Natural Selection.” Philosophical
Transactions of the Royal Society of London. Series B, Biological Sciences.
Royal Society, 2010. https://doi.org/10.1098/rstb.2010.0106.
ieee: N. H. Barton, “Genetic linkage and natural selection,” Philosophical Transactions
of the Royal Society of London. Series B, Biological Sciences, vol. 365, no.
1552. Royal Society, pp. 2559–2569, 2010.
ista: Barton NH. 2010. Genetic linkage and natural selection. Philosophical Transactions
of the Royal Society of London. Series B, Biological Sciences. 365(1552), 2559–2569.
mla: Barton, Nicholas H. “Genetic Linkage and Natural Selection.” Philosophical
Transactions of the Royal Society of London. Series B, Biological Sciences,
vol. 365, no. 1552, Royal Society, 2010, pp. 2559–69, doi:10.1098/rstb.2010.0106.
short: N.H. Barton, Philosophical Transactions of the Royal Society of London. Series
B, Biological Sciences 365 (2010) 2559–2569.
date_created: 2018-12-11T12:05:06Z
date_published: 2010-08-27T00:00:00Z
date_updated: 2021-01-12T07:52:07Z
day: '27'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1098/rstb.2010.0106
file:
- access_level: open_access
checksum: 4d8aade10db030124ab158b622e337e0
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:14:40Z
date_updated: 2020-07-14T12:46:15Z
file_id: '5093'
file_name: IST-2016-555-v1+1_RS2009_revised.pdf
file_size: 250255
relation: main_file
file_date_updated: 2020-07-14T12:46:15Z
has_accepted_license: '1'
intvolume: ' 365'
issue: '1552'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Submitted Version
page: 2559 - 2569
publication: Philosophical Transactions of the Royal Society of London. Series B,
Biological Sciences
publication_status: published
publisher: Royal Society
publist_id: '2450'
pubrep_id: '555'
quality_controlled: '1'
scopus_import: 1
status: public
title: Genetic linkage and natural selection
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 365
year: '2010'
...
---
_id: '3777'
abstract:
- lang: eng
text: 'Under the classical view, selection depends more or less directly on mutation:
standing genetic variance is maintained by a balance between selection and mutation,
and adaptation is fuelled by new favourable mutations. Recombination is favoured
if it breaks negative associations among selected alleles, which interfere with
adaptation. Such associations may be generated by negative epistasis, or by random
drift (leading to the Hill-Robertson effect). Both deterministic and stochastic
explanations depend primarily on the genomic mutation rate, U. This may be large
enough to explain high recombination rates in some organisms, but seems unlikely
to be so in general. Random drift is a more general source of negative linkage
disequilibria, and can cause selection for recombination even in large populations,
through the chance loss of new favourable mutations. The rate of species-wide
substitutions is much too low to drive this mechanism, but local fluctuations
in selection, combined with gene flow, may suffice. These arguments are illustrated
by comparing the interaction between good and bad mutations at unlinked loci under
the infinitesimal model.'
acknowledgement: I would like to thank W. G. Hill and L. Loewe for organizing this
special issue, and the Royal Society and Wolfson Foundation for their support. Also,
A. Kondrashov and L. Loewe gave very helpful comments that helped improve the manuscript.
author:
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: Barton NH. Mutation and the evolution of recombination. Philosophical Transactions
of the Royal Society of London Series B, Biological Sciences. 2010;365(1544):1281-1294.
doi:10.1098/rstb.2009.0320
apa: Barton, N. H. (2010). Mutation and the evolution of recombination. Philosophical
Transactions of the Royal Society of London. Series B, Biological Sciences.
Royal Society. https://doi.org/10.1098/rstb.2009.0320
chicago: Barton, Nicholas H. “Mutation and the Evolution of Recombination.” Philosophical
Transactions of the Royal Society of London. Series B, Biological Sciences.
Royal Society, 2010. https://doi.org/10.1098/rstb.2009.0320.
ieee: N. H. Barton, “Mutation and the evolution of recombination,” Philosophical
Transactions of the Royal Society of London. Series B, Biological Sciences,
vol. 365, no. 1544. Royal Society, pp. 1281–1294, 2010.
ista: Barton NH. 2010. Mutation and the evolution of recombination. Philosophical
Transactions of the Royal Society of London. Series B, Biological Sciences. 365(1544),
1281–1294.
mla: Barton, Nicholas H. “Mutation and the Evolution of Recombination.” Philosophical
Transactions of the Royal Society of London. Series B, Biological Sciences,
vol. 365, no. 1544, Royal Society, 2010, pp. 1281–94, doi:10.1098/rstb.2009.0320.
short: N.H. Barton, Philosophical Transactions of the Royal Society of London. Series
B, Biological Sciences 365 (2010) 1281–1294.
date_created: 2018-12-11T12:05:07Z
date_published: 2010-04-27T00:00:00Z
date_updated: 2021-01-12T07:52:07Z
day: '27'
department:
- _id: NiBa
doi: 10.1098/rstb.2009.0320
external_id:
pmid:
- '20308104'
intvolume: ' 365'
issue: '1544'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pubmed/20308104
month: '04'
oa: 1
oa_version: Submitted Version
page: 1281 - 1294
pmid: 1
publication: Philosophical Transactions of the Royal Society of London. Series B,
Biological Sciences
publication_status: published
publisher: Royal Society
publist_id: '2451'
quality_controlled: '1'
scopus_import: 1
status: public
title: Mutation and the evolution of recombination
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 365
year: '2010'
...
---
_id: '3779'
abstract:
- lang: eng
text: Crosses between closely related species give two contrasting results. One
result is that species hybrids may be inferior to their parents, for example,
being less fertile [1]. The other is that F1 hybrids may display superior performance
(heterosis), for example with increased vigour [2]. Although various hypotheses
have been proposed to account for these two aspects of hybridisation, their biological
basis is still poorly understood [3]. To gain further insights into this issue,
we analysed the role that variation in gene expression may play. We took a conserved
trait, flower asymmetry in Antirrhinum, and determined the extent to which the
underlying regulatory genes varied in expression among closely related species.
We show that expression of both genes analysed, CYC and RAD, varies significantly
between species because of cis-acting differences. By making a quantitative genotype-phenotype
map, using a range of mutant alleles, we demonstrate that the species lie on a
plateau in gene expression-morphology space, so that the variation has no detectable
phenotypic effect. However, phenotypic differences can be revealed by shifting
genotypes off the plateau through genetic crosses. Our results can be readily
explained if genomes are free to evolve within an effectively neutral zone in
gene expression space. The consequences of this drift will be negligible for individual
loci, but when multiple loci across the genome are considered, we show that the
variation may have significant effects on phenotype and fitness, causing a significant
drift load. By considering these consequences for various gene-expression-fitness
landscapes, we conclude that F1 hybrids might be expected to show increased performance
with regard to conserved traits, such as basic physiology, but reduced performance
with regard to others. Thus, our study provides a new way of explaining how various
aspects of hybrid performance may arise through natural variation in gene activity.
acknowledgement: "This was supported by a Marie Curie grant for early stage training
and the BBSRC-John Innes Centre PhD Rotation Program.\r\nWe would like to thank
X. Feng and A. Hudson for assistance with introgressions and genotyping; A. Green,
A. Bangham and J. Pateman for advice and assistance on shape model procedures; F.
Alderson and S.Mitchell from JIC horticultural services; P.J. Wittkopp for protocols
and advice on pyrosequencing; and R. Sablowski for discussions and comments.\r\n"
article_number: e1000429
author:
- first_name: Ulises
full_name: Rosas, Ulises
last_name: Rosas
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: Lucy
full_name: Copsey, Lucy
last_name: Copsey
- first_name: Pierre
full_name: Barbier De Reuille, Pierre
last_name: Barbier De Reuille
- first_name: Enrico
full_name: Coen, Enrico
last_name: Coen
citation:
ama: Rosas U, Barton NH, Copsey L, Barbier De Reuille P, Coen E. Cryptic variation
between species and the basis of hybrid performance. PLoS Biology. 2010;8(7).
doi:10.1371/journal.pbio.1000429
apa: Rosas, U., Barton, N. H., Copsey, L., Barbier De Reuille, P., & Coen, E.
(2010). Cryptic variation between species and the basis of hybrid performance.
PLoS Biology. Public Library of Science. https://doi.org/10.1371/journal.pbio.1000429
chicago: Rosas, Ulises, Nicholas H Barton, Lucy Copsey, Pierre Barbier De Reuille,
and Enrico Coen. “Cryptic Variation between Species and the Basis of Hybrid Performance.”
PLoS Biology. Public Library of Science, 2010. https://doi.org/10.1371/journal.pbio.1000429.
ieee: U. Rosas, N. H. Barton, L. Copsey, P. Barbier De Reuille, and E. Coen, “Cryptic
variation between species and the basis of hybrid performance,” PLoS Biology,
vol. 8, no. 7. Public Library of Science, 2010.
ista: Rosas U, Barton NH, Copsey L, Barbier De Reuille P, Coen E. 2010. Cryptic
variation between species and the basis of hybrid performance. PLoS Biology. 8(7),
e1000429.
mla: Rosas, Ulises, et al. “Cryptic Variation between Species and the Basis of Hybrid
Performance.” PLoS Biology, vol. 8, no. 7, e1000429, Public Library of
Science, 2010, doi:10.1371/journal.pbio.1000429.
short: U. Rosas, N.H. Barton, L. Copsey, P. Barbier De Reuille, E. Coen, PLoS Biology
8 (2010).
date_created: 2018-12-11T12:05:07Z
date_published: 2010-07-20T00:00:00Z
date_updated: 2023-02-23T14:07:34Z
day: '20'
ddc:
- '576'
department:
- _id: NiBa
doi: 10.1371/journal.pbio.1000429
file:
- access_level: open_access
checksum: ee1ce2fb283a6b4127544ae532d0b4a1
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:14:11Z
date_updated: 2020-07-14T12:46:15Z
file_id: '5060'
file_name: IST-2015-366-v1+1_journal.pbio.1000429.pdf
file_size: 1089530
relation: main_file
file_date_updated: 2020-07-14T12:46:15Z
has_accepted_license: '1'
intvolume: ' 8'
issue: '7'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
publication: PLoS Biology
publication_status: published
publisher: Public Library of Science
publist_id: '2448'
pubrep_id: '366'
quality_controlled: '1'
related_material:
record:
- id: '9764'
relation: research_data
status: public
scopus_import: 1
status: public
title: Cryptic variation between species and the basis of hybrid performance
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2010'
...
---
_id: '3782'
abstract:
- lang: eng
text: In cortex surface segmentation, the extracted surface is required to have
a particular topology, namely, a two-sphere. We present a new method for removing
topology noise of a curve or surface within the level set framework, and thus
produce a cortical surface with correct topology. We define a new energy term
which quantifies topology noise. We then show how to minimize this term by computing
its functional derivative with respect to the level set function. This method
differs from existing methods in that it is inherently continuous and not digital;
and in the way that our energy directly relates to the topology of the underlying
curve or surface, versus existing knot-based measures which are related in a more
indirect fashion. The proposed flow is validated empirically.
acknowledgement: "Partially supported by the Austri an Science Fund unde r grant P20134-N13.\r\nWe
thank Helena Molina-Abril for very helpful discussion. We thank anonymous reviewers
for helpful comments."
alternative_title:
- LNCS
author:
- first_name: Chao
full_name: Chen, Chao
id: 3E92416E-F248-11E8-B48F-1D18A9856A87
last_name: Chen
- first_name: Daniel
full_name: Freedman, Daniel
last_name: Freedman
citation:
ama: 'Chen C, Freedman D. Topology noise removal for curve and surface evolution.
In: Conference Proceedings MCV 2010. Vol 6533. Springer; 2010:31-42. doi:10.1007/978-3-642-18421-5_4'
apa: 'Chen, C., & Freedman, D. (2010). Topology noise removal for curve and
surface evolution. In Conference proceedings MCV 2010 (Vol. 6533, pp.
31–42). Beijing, China: Springer. https://doi.org/10.1007/978-3-642-18421-5_4'
chicago: Chen, Chao, and Daniel Freedman. “Topology Noise Removal for Curve and
Surface Evolution.” In Conference Proceedings MCV 2010, 6533:31–42. Springer,
2010. https://doi.org/10.1007/978-3-642-18421-5_4.
ieee: C. Chen and D. Freedman, “Topology noise removal for curve and surface evolution,”
in Conference proceedings MCV 2010, Beijing, China, 2010, vol. 6533, pp.
31–42.
ista: 'Chen C, Freedman D. 2010. Topology noise removal for curve and surface evolution. Conference
proceedings MCV 2010. MCV: Medical Computer Vision, LNCS, vol. 6533, 31–42.'
mla: Chen, Chao, and Daniel Freedman. “Topology Noise Removal for Curve and Surface
Evolution.” Conference Proceedings MCV 2010, vol. 6533, Springer, 2010,
pp. 31–42, doi:10.1007/978-3-642-18421-5_4.
short: C. Chen, D. Freedman, in:, Conference Proceedings MCV 2010, Springer, 2010,
pp. 31–42.
conference:
end_date: 2010-09-20
location: Beijing, China
name: 'MCV: Medical Computer Vision'
start_date: 2010-09-20
date_created: 2018-12-11T12:05:08Z
date_published: 2010-12-31T00:00:00Z
date_updated: 2021-01-12T07:52:10Z
day: '31'
department:
- _id: HeEd
doi: 10.1007/978-3-642-18421-5_4
intvolume: ' 6533'
language:
- iso: eng
month: '12'
oa_version: None
page: 31 - 42
publication: ' Conference proceedings MCV 2010'
publication_status: published
publisher: Springer
publist_id: '2445'
quality_controlled: '1'
scopus_import: 1
status: public
title: Topology noise removal for curve and surface evolution
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 6533
year: '2010'
...
---
_id: '3783'
abstract:
- lang: eng
text: MICROSATELIGHT is a Perl/Tk pipeline with a graphical user interface that
facilitates several tasks when scoring microsatellites. It implements new subroutines
in R and PERL and takes advantage of features provided by previously developed
freeware. MICROSATELIGHT takes raw genotype data and automates the peak identification
through PeakScanner. The PeakSelect subroutine assigns peaks to different microsatellite
markers according to their multiplex group, fluorochrome type, and size range.
After peak selection, binning of alleles can be carried out 1) automatically through
AlleloBin or 2) by manual bin definition through Binator. In both cases, several
features for quality checking and further binning improvement are provided. The
genotype table can then be converted into input files for several population genetics
programs through CREATE. Finally, Hardy–Weinberg equilibrium tests and confidence
intervals for null allele frequency can be obtained through GENEPOP. MICROSATELIGHT
is the only freely available public-domain software that facilitates full multiplex
microsatellite scoring, from electropherogram files to user-defined text files
to be used with population genetics software. MICROSATELIGHT has been created
for the Windows XP operating system and has been successfully tested under Windows
7. It is available at http://sourceforge.net/projects/microsatelight/.
acknowledgement: "Ministerio de Educación y Ciencia (CGL2006-13423, CTM2007-66635).
M.P. and FP are part of the research group 2009SGR-636 of the Generalitat de Catalunya.
F.P. acknowledges an EU-Synthesys grant (GB-TAF-4474).\r\n\r\nThanks to José Gabriel
Segarra-Moragues (Centro de Investigaciones sobre Desertificación) for sending us
pictures with several types of stuttering and Pedro Simões and Gemma Calàbria (Universitat
de Barcelona) for testing this software. Finally, thanks are due to 2 anonymous
referees for their valuable comments. These comments certainly helped to improve
the manuscript."
author:
- first_name: Ferran
full_name: Palero, Ferran
id: 3F0E2A22-F248-11E8-B48F-1D18A9856A87
last_name: Palero
orcid: 0000-0002-0343-8329
- first_name: Fernando
full_name: González Candelas, Fernando
last_name: González Candelas
- first_name: Marta
full_name: Pascual, Marta
last_name: Pascual
citation:
ama: Palero F, González Candelas F, Pascual M. Microsatelight – Pipeline to expedite
microsatellite analysis. Journal of Heredity. 2010;102(2):247-249. doi:10.1093/jhered/esq111
apa: Palero, F., González Candelas, F., & Pascual, M. (2010). Microsatelight
– Pipeline to expedite microsatellite analysis. Journal of Heredity. Oxford
University Press. https://doi.org/10.1093/jhered/esq111
chicago: Palero, Ferran, Fernando González Candelas, and Marta Pascual. “Microsatelight
– Pipeline to Expedite Microsatellite Analysis.” Journal of Heredity. Oxford
University Press, 2010. https://doi.org/10.1093/jhered/esq111.
ieee: F. Palero, F. González Candelas, and M. Pascual, “Microsatelight – Pipeline
to expedite microsatellite analysis,” Journal of Heredity, vol. 102, no.
2. Oxford University Press, pp. 247–249, 2010.
ista: Palero F, González Candelas F, Pascual M. 2010. Microsatelight – Pipeline
to expedite microsatellite analysis. Journal of Heredity. 102(2), 247–249.
mla: Palero, Ferran, et al. “Microsatelight – Pipeline to Expedite Microsatellite
Analysis.” Journal of Heredity, vol. 102, no. 2, Oxford University Press,
2010, pp. 247–49, doi:10.1093/jhered/esq111.
short: F. Palero, F. González Candelas, M. Pascual, Journal of Heredity 102 (2010)
247–249.
date_created: 2018-12-11T12:05:09Z
date_published: 2010-12-02T00:00:00Z
date_updated: 2021-01-12T07:52:10Z
day: '02'
department:
- _id: NiBa
doi: 10.1093/jhered/esq111
intvolume: ' 102'
issue: '2'
language:
- iso: eng
month: '12'
oa_version: None
page: 247 - 249
publication: Journal of Heredity
publication_status: published
publisher: Oxford University Press
publist_id: '2444'
quality_controlled: '1'
scopus_import: 1
status: public
title: Microsatelight – Pipeline to expedite microsatellite analysis
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 102
year: '2010'
...
---
_id: '3785'
abstract:
- lang: eng
text: Most fisheries involving spiny lobsters of the genus Palinurus have been over
exploited during the last decades, so there is a raising concern about management
decisions for these valuable resources. A total of 13 microsatellite DNA loci
recently developed in Palinurus elephas were assayed in order to assess genetic diversity levels in every known species of the genus. Microsatellite markers gave
amplifications and showed polymorphism in all species, with gene diversity values varying from 0.65060.077 SD (Palinurus
barbarae) to 0.79260.051 SD (Palinurus elephas). Most importantly, when depth
distribution was taken into account, shallower waters pecies consistently showed
larger historical effective population sizes than their deeper-water counterparts. This
could explain why deeper-water species are more sensitive to overfishing, and
would indicate that overexploitation may have a larger impact on their long-term
genetic diversity.
article_processing_charge: No
author:
- first_name: Ferran
full_name: Palero, Ferran
id: 3F0E2A22-F248-11E8-B48F-1D18A9856A87
last_name: Palero
orcid: 0000-0002-0343-8329
- first_name: Pere
full_name: Abello, Pere
last_name: Abello
- first_name: E.
full_name: Macpherson, E.
last_name: Macpherson
- first_name: C.
full_name: Matthee, C.
last_name: Matthee
- first_name: Marta
full_name: Pascual, Marta
last_name: Pascual
citation:
ama: 'Palero F, Abello P, Macpherson E, Matthee C, Pascual M. Genetic diversity
levels in fishery-exploited spiny lobsters of the Genus Palinurus (Decapoda: Achelata).
Journal of Crustacean Biology. 2010;30(4):658-663. doi:10.1651/09-3192.1'
apa: 'Palero, F., Abello, P., Macpherson, E., Matthee, C., & Pascual, M. (2010).
Genetic diversity levels in fishery-exploited spiny lobsters of the Genus Palinurus
(Decapoda: Achelata). Journal of Crustacean Biology. Oxford University
Press. https://doi.org/10.1651/09-3192.1'
chicago: 'Palero, Ferran, Pere Abello, E. Macpherson, C. Matthee, and Marta Pascual.
“Genetic Diversity Levels in Fishery-Exploited Spiny Lobsters of the Genus Palinurus
(Decapoda: Achelata).” Journal of Crustacean Biology. Oxford University
Press, 2010. https://doi.org/10.1651/09-3192.1.'
ieee: 'F. Palero, P. Abello, E. Macpherson, C. Matthee, and M. Pascual, “Genetic
diversity levels in fishery-exploited spiny lobsters of the Genus Palinurus (Decapoda:
Achelata),” Journal of Crustacean Biology, vol. 30, no. 4. Oxford University
Press, pp. 658–663, 2010.'
ista: 'Palero F, Abello P, Macpherson E, Matthee C, Pascual M. 2010. Genetic diversity
levels in fishery-exploited spiny lobsters of the Genus Palinurus (Decapoda: Achelata).
Journal of Crustacean Biology. 30(4), 658–663.'
mla: 'Palero, Ferran, et al. “Genetic Diversity Levels in Fishery-Exploited Spiny
Lobsters of the Genus Palinurus (Decapoda: Achelata).” Journal of Crustacean
Biology, vol. 30, no. 4, Oxford University Press, 2010, pp. 658–63, doi:10.1651/09-3192.1.'
short: F. Palero, P. Abello, E. Macpherson, C. Matthee, M. Pascual, Journal of Crustacean
Biology 30 (2010) 658–663.
date_created: 2018-12-11T12:05:09Z
date_published: 2010-10-01T00:00:00Z
date_updated: 2023-10-16T09:51:05Z
day: '01'
department:
- _id: NiBa
doi: 10.1651/09-3192.1
intvolume: ' 30'
issue: '4'
language:
- iso: eng
month: '10'
oa_version: None
page: 658 - 663
publication: Journal of Crustacean Biology
publication_identifier:
eissn:
- 1937-240X
issn:
- 0278-0372
publication_status: published
publisher: Oxford University Press
publist_id: '2442'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Genetic diversity levels in fishery-exploited spiny lobsters of the Genus
Palinurus (Decapoda: Achelata)'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 30
year: '2010'
...
---
_id: '3786'
abstract:
- lang: eng
text: Four rare palinurid phyllosoma larvae, one mid-stage and three final stage,
were found among the unclassified collections in the Crustacea Section, Natural
History Museum, London. Detailed morphological analysis of the larvae indicated
that they belong to several Palinustus species given the presence of incipient
blunt-horns, length of antennula, length ratio of segments of antennular peduncle,
distribution of pereiopod spines, and shape of uropods and telson. Moreover, the
size of the final-stage larvae agrees with that expected given the size of the
recently described puerulus stage of Palinustus mossambicus. This constitutes
the first description of a complete phyllosoma assigned to Palinustus species.
The phyllosoma described in the present study include the largest Palinuridae
larva ever found.
article_processing_charge: No
article_type: original
author:
- first_name: Ferran
full_name: Palero, Ferran
id: 3F0E2A22-F248-11E8-B48F-1D18A9856A87
last_name: Palero
orcid: 0000-0002-0343-8329
- first_name: Guillermo
full_name: Guerao, Guillermo
last_name: Guerao
- first_name: Paul
full_name: Clark, Paul
last_name: Clark
- first_name: Pere
full_name: Abello, Pere
last_name: Abello
citation:
ama: 'Palero F, Guerao G, Clark P, Abello P. Final-stage phyllosoma of Palinustus
A. Milne-Edwards, 1880 (Crustacea: Decapoda: Achelata: Palinuridae)-The first
complete description. Zootaxa. 2010;2403(1):42-58. doi:10.11646/zootaxa.2403.1.4'
apa: 'Palero, F., Guerao, G., Clark, P., & Abello, P. (2010). Final-stage phyllosoma
of Palinustus A. Milne-Edwards, 1880 (Crustacea: Decapoda: Achelata: Palinuridae)-The
first complete description. Zootaxa. Magnolia Press. https://doi.org/10.11646/zootaxa.2403.1.4'
chicago: 'Palero, Ferran, Guillermo Guerao, Paul Clark, and Pere Abello. “Final-Stage
Phyllosoma of Palinustus A. Milne-Edwards, 1880 (Crustacea: Decapoda: Achelata:
Palinuridae)-The First Complete Description.” Zootaxa. Magnolia Press,
2010. https://doi.org/10.11646/zootaxa.2403.1.4.'
ieee: 'F. Palero, G. Guerao, P. Clark, and P. Abello, “Final-stage phyllosoma of
Palinustus A. Milne-Edwards, 1880 (Crustacea: Decapoda: Achelata: Palinuridae)-The
first complete description,” Zootaxa, vol. 2403, no. 1. Magnolia Press,
pp. 42–58, 2010.'
ista: 'Palero F, Guerao G, Clark P, Abello P. 2010. Final-stage phyllosoma of Palinustus
A. Milne-Edwards, 1880 (Crustacea: Decapoda: Achelata: Palinuridae)-The first
complete description. Zootaxa. 2403(1), 42–58.'
mla: 'Palero, Ferran, et al. “Final-Stage Phyllosoma of Palinustus A. Milne-Edwards,
1880 (Crustacea: Decapoda: Achelata: Palinuridae)-The First Complete Description.”
Zootaxa, vol. 2403, no. 1, Magnolia Press, 2010, pp. 42–58, doi:10.11646/zootaxa.2403.1.4.'
short: F. Palero, G. Guerao, P. Clark, P. Abello, Zootaxa 2403 (2010) 42–58.
date_created: 2018-12-11T12:05:10Z
date_published: 2010-03-19T00:00:00Z
date_updated: 2022-03-21T08:22:58Z
day: '19'
department:
- _id: NiBa
doi: 10.11646/zootaxa.2403.1.4
intvolume: ' 2403'
issue: '1'
language:
- iso: eng
month: '03'
oa_version: None
page: 42 - 58
publication: Zootaxa
publication_status: published
publisher: Magnolia Press
publist_id: '2441'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Final-stage phyllosoma of Palinustus A. Milne-Edwards, 1880 (Crustacea: Decapoda:
Achelata: Palinuridae)-The first complete description'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2403
year: '2010'
...
---
_id: '3787'
abstract:
- lang: eng
text: DNA samples were extracted from ethanol and formalin-fixed decapod crustacean
tissue using a new method based on Tetramethylsilane (TMS)-Chelex. It is shown
that neither an indigestible matrix of cross-linked protein nor soluble PCR inhibitors
impede PCR success when dealing with formalin-fixed material. Instead, amplification
success from formalin-fixed tissue appears to depend on the presence of unmodified
DNA in the extracted sample. A staining method that facilitates the targeting
of samples with a high content of unmodified DNA is provided.
acknowledgement: "The authors would like to thank two anonymous reviewers for their
remarks, which helped to improve the manuscript. This project was supported by the
Marine Biodiversity and Ecosystem Functioning Network of Excellence MarBEF (Contract
no. GOCE-CT-2003-505446) of the 6th European Framework Programme(FP6), the Zoology
Research Fund, Department of Zoology, NHM, London, a Research Grant from the Royal
Society to S.T., and a pre-doctoral fellowship awarded by the Autonomous Government
of Catalonia to F.P.(2006FIC-00082). This research received support from the SYNTHESYS
Project http://www.synthesys. info/ which is financed by European Community Research
Infrastructure Action under the FP6 “Structuring the European Research Area” Programme.
Many thanks are due to J. Fortuño for suggesting TMS as an alternative to critical
point drying, P.Crabb for helping with the UV-light photography setting and our
colleagues/friends in the Whale Basement Molecular Laboratories, Department of Zoology
NHM \r\n\r\n"
author:
- first_name: Ferran
full_name: Palero, Ferran
id: 3F0E2A22-F248-11E8-B48F-1D18A9856A87
last_name: Palero
orcid: 0000-0002-0343-8329
- first_name: Sally
full_name: Hall, Sally
last_name: Hall
- first_name: Paul
full_name: Clark, Paul
last_name: Clark
- first_name: David
full_name: Johnston, David
last_name: Johnston
- first_name: Jackie
full_name: Mackenzie Dodds, Jackie
last_name: Mackenzie Dodds
- first_name: Sven
full_name: Thatje, Sven
last_name: Thatje
citation:
ama: 'Palero F, Hall S, Clark P, Johnston D, Mackenzie Dodds J, Thatje S. DNA extraction
from formalin-fixed tissue: new light from the deep sea. Scientia Marina.
2010;74(3):465-470. doi:10.3989/scimar.2010.74n3465'
apa: 'Palero, F., Hall, S., Clark, P., Johnston, D., Mackenzie Dodds, J., &
Thatje, S. (2010). DNA extraction from formalin-fixed tissue: new light from the
deep sea. Scientia Marina. Consejo Superior de Investigaciones Científicas.
https://doi.org/10.3989/scimar.2010.74n3465'
chicago: 'Palero, Ferran, Sally Hall, Paul Clark, David Johnston, Jackie Mackenzie
Dodds, and Sven Thatje. “DNA Extraction from Formalin-Fixed Tissue: New Light
from the Deep Sea.” Scientia Marina. Consejo Superior de Investigaciones
Científicas, 2010. https://doi.org/10.3989/scimar.2010.74n3465.'
ieee: 'F. Palero, S. Hall, P. Clark, D. Johnston, J. Mackenzie Dodds, and S. Thatje,
“DNA extraction from formalin-fixed tissue: new light from the deep sea,” Scientia
Marina, vol. 74, no. 3. Consejo Superior de Investigaciones Científicas, pp.
465–470, 2010.'
ista: 'Palero F, Hall S, Clark P, Johnston D, Mackenzie Dodds J, Thatje S. 2010.
DNA extraction from formalin-fixed tissue: new light from the deep sea. Scientia
Marina. 74(3), 465–470.'
mla: 'Palero, Ferran, et al. “DNA Extraction from Formalin-Fixed Tissue: New Light
from the Deep Sea.” Scientia Marina, vol. 74, no. 3, Consejo Superior de
Investigaciones Científicas, 2010, pp. 465–70, doi:10.3989/scimar.2010.74n3465.'
short: F. Palero, S. Hall, P. Clark, D. Johnston, J. Mackenzie Dodds, S. Thatje,
Scientia Marina 74 (2010) 465–470.
date_created: 2018-12-11T12:05:10Z
date_published: 2010-09-01T00:00:00Z
date_updated: 2021-01-12T07:52:11Z
day: '01'
department:
- _id: NiBa
doi: 10.3989/scimar.2010.74n3465
intvolume: ' 74'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://eprints.soton.ac.uk/68731/
month: '09'
oa: 1
oa_version: Submitted Version
page: 465 - 470
publication: Scientia Marina
publication_status: published
publisher: Consejo Superior de Investigaciones Científicas
publist_id: '2440'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'DNA extraction from formalin-fixed tissue: new light from the deep sea'
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 74
year: '2010'
...
---
_id: '3788'
abstract:
- lang: eng
text: Cell sorting is a widespread phenomenon pivotal to the early development of
multicellular organisms. In vitro cell sorting studies have been instrumental
in revealing the cellular properties driving this process. However, these studies
have as yet been limited to two-dimensional analysis of three-dimensional cell
sorting events. Here we describe a method to record the sorting of primary zebrafish
ectoderm and mesoderm germ layer progenitor cells in three dimensions over time,
and quantitatively analyze their sorting behavior using an order parameter related
to heterotypic interface length. We investigate the cell population size dependence
of sorted aggregates and find that the germ layer progenitor cells engulfed in
the final configuration display a relationship between total interfacial length
and system size according to a simple geometrical argument, subject to a finite-size
effect.
author:
- first_name: Abigail
full_name: Klopper, Abigail
last_name: Klopper
- first_name: Gabriel
full_name: Krens, Gabriel
id: 2B819732-F248-11E8-B48F-1D18A9856A87
last_name: Krens
orcid: 0000-0003-4761-5996
- first_name: Stephan
full_name: Grill, Stephan
last_name: Grill
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: 'Klopper A, Krens G, Grill S, Heisenberg C-PJ. Finite-size corrections to scaling
behavior in sorted cell aggregates. The European Physical Journal E: Soft Matter
and Biological Physics. 2010;33(2):99-103. doi:10.1140/epje/i2010-10642-y'
apa: 'Klopper, A., Krens, G., Grill, S., & Heisenberg, C.-P. J. (2010). Finite-size
corrections to scaling behavior in sorted cell aggregates. The European Physical
Journal E: Soft Matter and Biological Physics. Springer. https://doi.org/10.1140/epje/i2010-10642-y'
chicago: 'Klopper, Abigail, Gabriel Krens, Stephan Grill, and Carl-Philipp J Heisenberg.
“Finite-Size Corrections to Scaling Behavior in Sorted Cell Aggregates.” The
European Physical Journal E: Soft Matter and Biological Physics. Springer,
2010. https://doi.org/10.1140/epje/i2010-10642-y.'
ieee: 'A. Klopper, G. Krens, S. Grill, and C.-P. J. Heisenberg, “Finite-size corrections
to scaling behavior in sorted cell aggregates,” The European Physical Journal
E: Soft Matter and Biological Physics, vol. 33, no. 2. Springer, pp. 99–103,
2010.'
ista: 'Klopper A, Krens G, Grill S, Heisenberg C-PJ. 2010. Finite-size corrections
to scaling behavior in sorted cell aggregates. The European Physical Journal E:
Soft Matter and Biological Physics. 33(2), 99–103.'
mla: 'Klopper, Abigail, et al. “Finite-Size Corrections to Scaling Behavior in Sorted
Cell Aggregates.” The European Physical Journal E: Soft Matter and Biological
Physics, vol. 33, no. 2, Springer, 2010, pp. 99–103, doi:10.1140/epje/i2010-10642-y.'
short: 'A. Klopper, G. Krens, S. Grill, C.-P.J. Heisenberg, The European Physical
Journal E: Soft Matter and Biological Physics 33 (2010) 99–103.'
date_created: 2018-12-11T12:05:10Z
date_published: 2010-09-18T00:00:00Z
date_updated: 2021-01-12T07:52:12Z
day: '18'
department:
- _id: CaHe
doi: 10.1140/epje/i2010-10642-y
intvolume: ' 33'
issue: '2'
language:
- iso: eng
month: '09'
oa_version: None
page: 99 - 103
publication: 'The European Physical Journal E: Soft Matter and Biological Physics'
publication_status: published
publisher: Springer
publist_id: '2439'
scopus_import: 1
status: public
title: Finite-size corrections to scaling behavior in sorted cell aggregates
type: journal_article
user_id: 2EBD1598-F248-11E8-B48F-1D18A9856A87
volume: 33
year: '2010'
...
---
_id: '3789'
abstract:
- lang: eng
text: 'The development of multicellular organisms is dependent on the tight coordination
between tissue growth and morphogenesis. The stereotypical orientation of cell
divisions has been proposed to be a fundamental mechanism by which proliferating
and growing tissues take shape. However, the actual contribution of stereotypical
division orientation (SDO) to tissue morphogenesis is unclear. In zebrafish, cell
divisions with stereotypical orientation have been implicated in both body-axis
elongation and neural rod formation [1, 2], although there is little direct evidence
for a critical function of SDO in either of these processes. Here we show that
SDO is required for formation of the neural rod midline during neurulation but
dispensable for elongation of the body axis during gastrulation. Our data indicate
that SDO during both gastrulation and neurulation is dependent on the noncanonical
Wnt receptor Frizzled 7 (Fz7) and that interfering with cell division orientation
leads to severe defects in neural rod midline formation but not body-axis elongation.
These findings suggest a novel function for Fz7-controlled cell division orientation
in neural rod midline formation during neurulation. '
acknowledgement: "This work was supported by grants from the Fundacion Caja Madrid
to E.Q.H. and the Institute of Science and Technology Austria, the Max-Planck-Society,
and the Deutsche Forschungsgemeinschaft to C.P.H.\r\nWe are grateful to Jon Clarke,
Andy Oates, and Garrett Greenan for reading earlier versions of this manuscript.
We thank J. Peychl, H. Ibarra, and P. Pitrone for excellent assistance and advice
in multi-photon microscopy and D. White for assistance during the image-processing
steps. We also thank D. Panhans for technical assistance, the whole Heisenberg laboratory
for useful comments and discussions, and E. Lehmann, J. Hückmann, and G. Junghans
for excellent fish care. "
author:
- first_name: Elena
full_name: Quesada-Hernández, Elena
id: EA35229E-E909-11E9-8DF8-C90C5D5AF86E
last_name: Quesada-Hernández
- first_name: Luca
full_name: Caneparo, Luca
last_name: Caneparo
- first_name: Sylvia
full_name: Schneider, Sylvia
id: 1FAC36B0-E90A-11E9-9D2F-EF31CE0C9C2F
last_name: Schneider
- first_name: Sylke
full_name: Winkler, Sylke
last_name: Winkler
- first_name: Michael
full_name: Liebling, Michael
last_name: Liebling
- first_name: Scott
full_name: Fraser, Scott
last_name: Fraser
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Quesada-Hernández E, Caneparo L, Schneider S, et al. Stereotypical cell division
orientation controls neural rod midline formation in zebrafish. Current Biology.
2010;20(21):1966-1972. doi:10.1016/j.cub.2010.10.009
apa: Quesada-Hernández, E., Caneparo, L., Schneider, S., Winkler, S., Liebling,
M., Fraser, S., & Heisenberg, C.-P. J. (2010). Stereotypical cell division
orientation controls neural rod midline formation in zebrafish. Current Biology.
Cell Press. https://doi.org/10.1016/j.cub.2010.10.009
chicago: Quesada-Hernández, Elena, Luca Caneparo, Sylvia Schneider, Sylke Winkler,
Michael Liebling, Scott Fraser, and Carl-Philipp J Heisenberg. “Stereotypical
Cell Division Orientation Controls Neural Rod Midline Formation in Zebrafish.”
Current Biology. Cell Press, 2010. https://doi.org/10.1016/j.cub.2010.10.009.
ieee: E. Quesada-Hernández et al., “Stereotypical cell division orientation
controls neural rod midline formation in zebrafish,” Current Biology, vol.
20, no. 21. Cell Press, pp. 1966–1972, 2010.
ista: Quesada-Hernández E, Caneparo L, Schneider S, Winkler S, Liebling M, Fraser
S, Heisenberg C-PJ. 2010. Stereotypical cell division orientation controls neural
rod midline formation in zebrafish. Current Biology. 20(21), 1966–1972.
mla: Quesada-Hernández, Elena, et al. “Stereotypical Cell Division Orientation Controls
Neural Rod Midline Formation in Zebrafish.” Current Biology, vol. 20, no.
21, Cell Press, 2010, pp. 1966–72, doi:10.1016/j.cub.2010.10.009.
short: E. Quesada-Hernández, L. Caneparo, S. Schneider, S. Winkler, M. Liebling,
S. Fraser, C.-P.J. Heisenberg, Current Biology 20 (2010) 1966–1972.
date_created: 2018-12-11T12:05:11Z
date_published: 2010-11-09T00:00:00Z
date_updated: 2021-01-12T07:52:12Z
day: '09'
department:
- _id: CaHe
doi: 10.1016/j.cub.2010.10.009
intvolume: ' 20'
issue: '21'
language:
- iso: eng
month: '11'
oa_version: None
page: 1966 - 1972
publication: Current Biology
publication_status: published
publisher: Cell Press
publist_id: '2438'
quality_controlled: '1'
scopus_import: 1
status: public
title: Stereotypical cell division orientation controls neural rod midline formation
in zebrafish
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 20
year: '2010'
...
---
_id: '3790'
abstract:
- lang: eng
text: Cell shape and motility are primarily controlled by cellular mechanics. The
attachment of the plasma membrane to the underlying actomyosin cortex has been
proposed to be important for cellular processes involving membrane deformation.
However, little is known about the actual function of membrane-to-cortex attachment
(MCA) in cell protrusion formation and migration, in particular in the context
of the developing embryo. Here, we use a multidisciplinary approach to study MCA
in zebrafish mesoderm and endoderm (mesendoderm) germ layer progenitor cells,
which migrate using a combination of different protrusion types, namely, lamellipodia,
filopodia, and blebs, during zebrafish gastrulation. By interfering with the activity
of molecules linking the cortex to the membrane and measuring resulting changes
in MCA by atomic force microscopy, we show that reducing MCA in mesendoderm progenitors
increases the proportion of cellular blebs and reduces the directionality of cell
migration. We propose that MCA is a key parameter controlling the relative proportions
of different cell protrusion types in mesendoderm progenitors, and thus is key
in controlling directed migration during gastrulation.
acknowledgement: "We would like to thank A. G. Clark, S. Grill, A. Oates, E. Raz,
L. Rohde, and M. Zerial for reading earlier versions of the manuscript. We are grateful
to W. Zachariae, Y. Arboleda-Estudillo, S. Schneider, P. Stockinger, D. Panhans,
M. Biro, J. C. Olaya, and the BIOTEC/MPI-CBG zebrafish and imaging facilities for
help and advice at various stages of this project and to J. Helenius for help with
programming. This work was supported by grants from the Boehringer Ingelheim Fonds
to MK, the Polish Ministry of Science and Higher Education to E. P., and the Deutsche
Forschungsgemeinschaft (HE 3231/6-1 and PA 1590/1-1) to CPH and EP.\r\n"
article_number: e1000544
author:
- first_name: Alba
full_name: Diz Muñoz, Alba
last_name: Diz Muñoz
- first_name: Michael
full_name: Krieg, Michael
last_name: Krieg
- first_name: Martin
full_name: Bergert, Martin
last_name: Bergert
- first_name: Itziar
full_name: Ibarlucea Benitez, Itziar
last_name: Ibarlucea Benitez
- first_name: Daniel
full_name: Müller, Daniel
last_name: Müller
- first_name: Ewa
full_name: Paluch, Ewa
last_name: Paluch
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Diz Muñoz A, Krieg M, Bergert M, et al. Control of directed cell migration
in vivo by membrane-to-cortex attachment. PLoS Biology. 2010;8(11). doi:10.1371/journal.pbio.1000544
apa: Diz Muñoz, A., Krieg, M., Bergert, M., Ibarlucea Benitez, I., Müller, D., Paluch,
E., & Heisenberg, C.-P. J. (2010). Control of directed cell migration in vivo
by membrane-to-cortex attachment. PLoS Biology. Public Library of Science.
https://doi.org/10.1371/journal.pbio.1000544
chicago: Diz Muñoz, Alba, Michael Krieg, Martin Bergert, Itziar Ibarlucea Benitez,
Daniel Müller, Ewa Paluch, and Carl-Philipp J Heisenberg. “Control of Directed
Cell Migration in Vivo by Membrane-to-Cortex Attachment.” PLoS Biology.
Public Library of Science, 2010. https://doi.org/10.1371/journal.pbio.1000544.
ieee: A. Diz Muñoz et al., “Control of directed cell migration in vivo by
membrane-to-cortex attachment,” PLoS Biology, vol. 8, no. 11. Public Library
of Science, 2010.
ista: Diz Muñoz A, Krieg M, Bergert M, Ibarlucea Benitez I, Müller D, Paluch E,
Heisenberg C-PJ. 2010. Control of directed cell migration in vivo by membrane-to-cortex
attachment. PLoS Biology. 8(11), e1000544.
mla: Diz Muñoz, Alba, et al. “Control of Directed Cell Migration in Vivo by Membrane-to-Cortex
Attachment.” PLoS Biology, vol. 8, no. 11, e1000544, Public Library of
Science, 2010, doi:10.1371/journal.pbio.1000544.
short: A. Diz Muñoz, M. Krieg, M. Bergert, I. Ibarlucea Benitez, D. Müller, E. Paluch,
C.-P.J. Heisenberg, PLoS Biology 8 (2010).
date_created: 2018-12-11T12:05:11Z
date_published: 2010-11-30T00:00:00Z
date_updated: 2021-01-12T07:52:13Z
day: '30'
ddc:
- '576'
department:
- _id: CaHe
doi: 10.1371/journal.pbio.1000544
file:
- access_level: open_access
checksum: 52d18c90ca6b02234cea5e8b399b7f46
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:08:24Z
date_updated: 2020-07-14T12:46:16Z
file_id: '4685'
file_name: IST-2015-365-v1+1_journal.pbio.1000544.pdf
file_size: 799506
relation: main_file
file_date_updated: 2020-07-14T12:46:16Z
has_accepted_license: '1'
intvolume: ' 8'
issue: '11'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
publication: PLoS Biology
publication_status: published
publisher: Public Library of Science
publist_id: '2437'
pubrep_id: '365'
quality_controlled: '1'
scopus_import: 1
status: public
title: Control of directed cell migration in vivo by membrane-to-cortex attachment
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2010'
...
---
_id: '3792'
abstract:
- lang: eng
text: The yolk syncytial layer (YSL) plays crucial roles in early zebrafish development.
The YSL is a transient extra-embryonic syncytial tissue that forms during early
cleavage stages and persists until larval stages. During gastrulation, the YSL
undergoes highly dynamic movements, which are tightly coordinated with the movements
of the overlying germ layer progenitor cells, and has critical functions in cell
fate specification and morphogenesis of the early germ layers. Movement coordination
between the YSL and blastoderm cells is dependent on contact between these tissues,
and is probably required for the patterning and morphogenetic function of the
YSL. In this review, we will discuss recent advances in elucidating the molecular
and cellular mechanisms underlying the YSL morphogenesis and movement coordination
between the YSL and blastoderm during early development.
acknowledgement: "We are grateful to Valerie Virta and Jennifer Regan for reading
earlier versions of the review.\r\n"
article_processing_charge: No
author:
- first_name: Lara
full_name: Carvalho, Lara
last_name: Carvalho
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Carvalho L, Heisenberg C-PJ. The yolk syncytial layer in early, zebrafish development.
Trends in Cell Biology. 2010;20(10):586-592. doi:10.1016/j.tcb.2010.06.009
apa: Carvalho, L., & Heisenberg, C.-P. J. (2010). The yolk syncytial layer in
early, zebrafish development. Trends in Cell Biology. Cell Press. https://doi.org/10.1016/j.tcb.2010.06.009
chicago: Carvalho, Lara, and Carl-Philipp J Heisenberg. “The Yolk Syncytial Layer
in Early, Zebrafish Development.” Trends in Cell Biology. Cell Press, 2010.
https://doi.org/10.1016/j.tcb.2010.06.009.
ieee: L. Carvalho and C.-P. J. Heisenberg, “The yolk syncytial layer in early, zebrafish
development,” Trends in Cell Biology, vol. 20, no. 10. Cell Press, pp.
586–592, 2010.
ista: Carvalho L, Heisenberg C-PJ. 2010. The yolk syncytial layer in early, zebrafish
development. Trends in Cell Biology. 20(10), 586–592.
mla: Carvalho, Lara, and Carl-Philipp J. Heisenberg. “The Yolk Syncytial Layer in
Early, Zebrafish Development.” Trends in Cell Biology, vol. 20, no. 10,
Cell Press, 2010, pp. 586–92, doi:10.1016/j.tcb.2010.06.009.
short: L. Carvalho, C.-P.J. Heisenberg, Trends in Cell Biology 20 (2010) 586–592.
date_created: 2018-12-11T12:05:12Z
date_published: 2010-10-01T00:00:00Z
date_updated: 2022-08-25T15:00:19Z
day: '01'
doi: 10.1016/j.tcb.2010.06.009
intvolume: ' 20'
issue: '10'
language:
- iso: eng
month: '10'
oa_version: None
page: 586 - 592
publication: Trends in Cell Biology
publication_status: published
publisher: Cell Press
publist_id: '2435'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The yolk syncytial layer in early, zebrafish development
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 20
year: '2010'
...
---
_id: '3793'
abstract:
- lang: eng
text: "Recent progress in per-pixel object class labeling of natural images can
be attributed to the use of multiple types of image features and sound statistical
learning approaches. Within the latter, Conditional Random Fields (CRF) are prominently
used for their ability to represent interactions between random variables. Despite
their popularity in computer vision, parameter learning for CRFs has remained
difficult, popular approaches being cross-validation and piecewise training.\r\nIn
this work, we propose a simple yet expressive tree-structured CRF based on a recent
hierarchical image segmentation method. Our model combines and weights multiple
image features within a hierarchical representation and allows simple and efficient
globally-optimal learning of ≈ 105 parameters. The tractability of our model allows
us to pose and answer some of the open questions regarding parameter learning
applying to CRF-based approaches. The key findings for learning CRF models are,
from the obvious to the surprising, i) multiple image features always help, ii)
the limiting dimension with respect to current models is the amount of training
data, iii) piecewise training is competitive, iv) current methods for max-margin
training fail for models with many parameters.\r\n"
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Sebastian
full_name: Nowozin, Sebastian
last_name: Nowozin
- first_name: Peter
full_name: Gehler, Peter
last_name: Gehler
- first_name: Christoph
full_name: Lampert, Christoph
id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
last_name: Lampert
orcid: 0000-0001-8622-7887
citation:
ama: 'Nowozin S, Gehler P, Lampert C. On parameter learning in CRF-based approaches
to object class image segmentation. In: Vol 6316. Springer; 2010:98-111. doi:10.1007/978-3-642-15567-3_8'
apa: 'Nowozin, S., Gehler, P., & Lampert, C. (2010). On parameter learning in
CRF-based approaches to object class image segmentation (Vol. 6316, pp. 98–111).
Presented at the ECCV: European Conference on Computer Vision, Heraklion, Crete,
Greece: Springer. https://doi.org/10.1007/978-3-642-15567-3_8'
chicago: Nowozin, Sebastian, Peter Gehler, and Christoph Lampert. “On Parameter
Learning in CRF-Based Approaches to Object Class Image Segmentation,” 6316:98–111.
Springer, 2010. https://doi.org/10.1007/978-3-642-15567-3_8.
ieee: 'S. Nowozin, P. Gehler, and C. Lampert, “On parameter learning in CRF-based
approaches to object class image segmentation,” presented at the ECCV: European
Conference on Computer Vision, Heraklion, Crete, Greece, 2010, vol. 6316, pp.
98–111.'
ista: 'Nowozin S, Gehler P, Lampert C. 2010. On parameter learning in CRF-based
approaches to object class image segmentation. ECCV: European Conference on Computer
Vision, LNCS, vol. 6316, 98–111.'
mla: Nowozin, Sebastian, et al. On Parameter Learning in CRF-Based Approaches
to Object Class Image Segmentation. Vol. 6316, Springer, 2010, pp. 98–111,
doi:10.1007/978-3-642-15567-3_8.
short: S. Nowozin, P. Gehler, C. Lampert, in:, Springer, 2010, pp. 98–111.
conference:
end_date: 2010-09-11
location: Heraklion, Crete, Greece
name: 'ECCV: European Conference on Computer Vision'
start_date: 2010-09-05
date_created: 2018-12-11T12:05:12Z
date_published: 2010-11-04T00:00:00Z
date_updated: 2021-01-12T07:52:14Z
day: '04'
ddc:
- '000'
department:
- _id: ChLa
doi: 10.1007/978-3-642-15567-3_8
file:
- access_level: open_access
checksum: 3716e10e161f7c714fd17ec193a223c3
content_type: application/pdf
creator: dernst
date_created: 2020-05-19T16:27:34Z
date_updated: 2020-07-14T12:46:16Z
file_id: '7871'
file_name: 2010_ECCV_Nowozin.pdf
file_size: 4087332
relation: main_file
file_date_updated: 2020-07-14T12:46:16Z
has_accepted_license: '1'
intvolume: ' 6316'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Submitted Version
page: 98 - 111
publication_status: published
publisher: Springer
publist_id: '2431'
quality_controlled: '1'
scopus_import: 1
status: public
title: On parameter learning in CRF-based approaches to object class image segmentation
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 6316
year: '2010'
...
---
_id: '3794'
abstract:
- lang: eng
text: 'We study the problem of multimodal dimensionality reduction assuming that
data samples can be missing at training time, and not all data modalities may
be present at application time. Maximum covariance analysis, as a generalization
of PCA, has many desirable properties, but its application to practical problems
is limited by its need for perfectly paired data. We overcome this limitation
by a latent variable approach that allows working with weakly paired data and
is still able to efficiently process large datasets using standard numerical routines.
The resulting weakly paired maximum covariance analysis often finds better representations
than alternative methods, as we show in two exemplary tasks: texture discrimination
and transfer learning.'
alternative_title:
- LNCS
author:
- first_name: Christoph
full_name: Lampert, Christoph
id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
last_name: Lampert
orcid: 0000-0001-8622-7887
- first_name: Oliver
full_name: Krömer, Oliver
last_name: Krömer
citation:
ama: 'Lampert C, Krömer O. Weakly-paired maximum covariance analysis for multimodal
dimensionality reduction and transfer learning. In: Vol 6312. Springer; 2010:566-579.
doi:10.1007/978-3-642-15552-9_41'
apa: 'Lampert, C., & Krömer, O. (2010). Weakly-paired maximum covariance analysis
for multimodal dimensionality reduction and transfer learning (Vol. 6312, pp.
566–579). Presented at the ECCV: European Conference on Computer Vision, Heraklion,
Crete, Greece: Springer. https://doi.org/10.1007/978-3-642-15552-9_41'
chicago: Lampert, Christoph, and Oliver Krömer. “Weakly-Paired Maximum Covariance
Analysis for Multimodal Dimensionality Reduction and Transfer Learning,” 6312:566–79.
Springer, 2010. https://doi.org/10.1007/978-3-642-15552-9_41.
ieee: 'C. Lampert and O. Krömer, “Weakly-paired maximum covariance analysis for
multimodal dimensionality reduction and transfer learning,” presented at the ECCV:
European Conference on Computer Vision, Heraklion, Crete, Greece, 2010, vol. 6312,
pp. 566–579.'
ista: 'Lampert C, Krömer O. 2010. Weakly-paired maximum covariance analysis for
multimodal dimensionality reduction and transfer learning. ECCV: European Conference
on Computer Vision, LNCS, vol. 6312, 566–579.'
mla: Lampert, Christoph, and Oliver Krömer. Weakly-Paired Maximum Covariance
Analysis for Multimodal Dimensionality Reduction and Transfer Learning. Vol.
6312, Springer, 2010, pp. 566–79, doi:10.1007/978-3-642-15552-9_41.
short: C. Lampert, O. Krömer, in:, Springer, 2010, pp. 566–579.
conference:
end_date: 2010-09-11
location: Heraklion, Crete, Greece
name: 'ECCV: European Conference on Computer Vision'
start_date: 2010-09-05
date_created: 2018-12-11T12:05:12Z
date_published: 2010-11-10T00:00:00Z
date_updated: 2021-01-12T07:52:14Z
day: '10'
department:
- _id: ChLa
doi: 10.1007/978-3-642-15552-9_41
intvolume: ' 6312'
language:
- iso: eng
main_file_link:
- url: http://www.ics.forth.gr/eccv2010/intro.php
month: '11'
oa_version: None
page: 566 - 579
publication_status: published
publisher: Springer
publist_id: '2433'
quality_controlled: '1'
scopus_import: 1
status: public
title: Weakly-paired maximum covariance analysis for multimodal dimensionality reduction
and transfer learning
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 6312
year: '2010'
...
---
_id: '3795'
abstract:
- lang: eng
text: 'The (apparent) contour of a smooth mapping from a 2-manifold to the plane,
f: M → R2 , is the set of critical values, that is, the image of the points at
which the gradients of the two component functions are linearly dependent. Assuming
M is compact and orientable and measuring difference with the erosion distance,
we prove that the contour is stable.'
acknowledgement: This research is partially supported by the Defense Advanced Research
Projects Agency (DARPA) under grants HR0011-05-1-0007 and HR0011-05-1-0057.
alternative_title:
- Mathematics and Visualization
author:
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Dmitriy
full_name: Morozov, Dmitriy
last_name: Morozov
- first_name: Amit
full_name: Patel, Amit
id: 34A254A0-F248-11E8-B48F-1D18A9856A87
last_name: Patel
citation:
ama: 'Edelsbrunner H, Morozov D, Patel A. The stability of the apparent contour
of an orientable 2-manifold. In: Topological Data Analysis and Visualization:
Theory, Algorithms and Applications. Springer; 2010:27-42. doi:10.1007/978-3-642-15014-2_3'
apa: 'Edelsbrunner, H., Morozov, D., & Patel, A. (2010). The stability of the
apparent contour of an orientable 2-manifold. In Topological Data Analysis
and Visualization: Theory, Algorithms and Applications (pp. 27–42). Springer.
https://doi.org/10.1007/978-3-642-15014-2_3'
chicago: 'Edelsbrunner, Herbert, Dmitriy Morozov, and Amit Patel. “The Stability
of the Apparent Contour of an Orientable 2-Manifold.” In Topological Data Analysis
and Visualization: Theory, Algorithms and Applications, 27–42. Springer, 2010.
https://doi.org/10.1007/978-3-642-15014-2_3.'
ieee: 'H. Edelsbrunner, D. Morozov, and A. Patel, “The stability of the apparent
contour of an orientable 2-manifold,” in Topological Data Analysis and Visualization:
Theory, Algorithms and Applications, Springer, 2010, pp. 27–42.'
ista: 'Edelsbrunner H, Morozov D, Patel A. 2010.The stability of the apparent contour
of an orientable 2-manifold. In: Topological Data Analysis and Visualization:
Theory, Algorithms and Applications. Mathematics and Visualization, , 27–42.'
mla: 'Edelsbrunner, Herbert, et al. “The Stability of the Apparent Contour of an
Orientable 2-Manifold.” Topological Data Analysis and Visualization: Theory,
Algorithms and Applications, Springer, 2010, pp. 27–42, doi:10.1007/978-3-642-15014-2_3.'
short: 'H. Edelsbrunner, D. Morozov, A. Patel, in:, Topological Data Analysis and
Visualization: Theory, Algorithms and Applications, Springer, 2010, pp. 27–42.'
date_created: 2018-12-11T12:05:13Z
date_published: 2010-12-22T00:00:00Z
date_updated: 2021-01-12T07:52:15Z
day: '22'
ddc:
- '000'
department:
- _id: HeEd
doi: 10.1007/978-3-642-15014-2_3
file:
- access_level: open_access
checksum: f03a44c3d1c3e2d4fedb3b94404f3fd5
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:11:40Z
date_updated: 2020-07-14T12:46:16Z
file_id: '4896'
file_name: IST-2016-538-v1+1_2011-B-02-ApparentContour.pdf
file_size: 210710
relation: main_file
file_date_updated: 2020-07-14T12:46:16Z
has_accepted_license: '1'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Submitted Version
page: 27 - 42
publication: 'Topological Data Analysis and Visualization: Theory, Algorithms and
Applications'
publication_status: published
publisher: Springer
publist_id: '2428'
pubrep_id: '538'
quality_controlled: '1'
scopus_import: 1
status: public
title: The stability of the apparent contour of an orientable 2-manifold
type: book_chapter
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
year: '2010'
...
---
_id: '3829'
abstract:
- lang: eng
text: To determine the number of open Ca(2+) channels necessary for transmitter
release at the inhibitory basket cell-granule cell synapse in rat hippocampus,
we combined presynaptic Ca(2+) imaging, recording of postsynaptic currents and
modeling. We found that that the opening of three or fewer Ca(2+) channels triggered
transmitter release. Furthermore, a small number of Ca(2+) channels were able
to evoke release with high temporal precision, despite stochastic Ca(2+) channel
opening.
author:
- first_name: Iancu
full_name: Bucurenciu, Iancu
last_name: Bucurenciu
- first_name: Josef
full_name: Bischofberger, Josef
last_name: Bischofberger
- first_name: Peter M
full_name: Peter Jonas
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Bucurenciu I, Bischofberger J, Jonas PM. A small number of open Ca(2+) channels
trigger transmitter release at a central GABAergic synapse. Nature Neuroscience.
2010;13(1):19-21. doi:10.1038/nn.2461
apa: Bucurenciu, I., Bischofberger, J., & Jonas, P. M. (2010). A small number
of open Ca(2+) channels trigger transmitter release at a central GABAergic synapse.
Nature Neuroscience. Nature Publishing Group. https://doi.org/10.1038/nn.2461
chicago: Bucurenciu, Iancu, Josef Bischofberger, and Peter M Jonas. “A Small Number
of Open Ca(2+) Channels Trigger Transmitter Release at a Central GABAergic Synapse.”
Nature Neuroscience. Nature Publishing Group, 2010. https://doi.org/10.1038/nn.2461 .
ieee: I. Bucurenciu, J. Bischofberger, and P. M. Jonas, “A small number of open
Ca(2+) channels trigger transmitter release at a central GABAergic synapse,” Nature
Neuroscience, vol. 13, no. 1. Nature Publishing Group, pp. 19–21, 2010.
ista: Bucurenciu I, Bischofberger J, Jonas PM. 2010. A small number of open Ca(2+)
channels trigger transmitter release at a central GABAergic synapse. Nature Neuroscience.
13(1), 19–21.
mla: Bucurenciu, Iancu, et al. “A Small Number of Open Ca(2+) Channels Trigger Transmitter
Release at a Central GABAergic Synapse.” Nature Neuroscience, vol. 13,
no. 1, Nature Publishing Group, 2010, pp. 19–21, doi:10.1038/nn.2461 .
short: I. Bucurenciu, J. Bischofberger, P.M. Jonas, Nature Neuroscience 13 (2010)
19–21.
date_created: 2018-12-11T12:05:24Z
date_published: 2010-01-01T00:00:00Z
date_updated: 2021-01-12T07:52:29Z
day: '01'
doi: '10.1038/nn.2461 '
extern: 1
intvolume: ' 13'
issue: '1'
month: '01'
page: 19 - 21
publication: Nature Neuroscience
publication_status: published
publisher: Nature Publishing Group
publist_id: '2380'
quality_controlled: 0
status: public
title: A small number of open Ca(2+) channels trigger transmitter release at a central
GABAergic synapse
type: journal_article
volume: 13
year: '2010'
...
---
_id: '3830'
abstract:
- lang: eng
text: Fast-spiking, parvalbumin-expressing basket cells (BCs) are important for
feedforward and feedback inhibition. During network activity, BCs respond with
short latency and high temporal precision. It is thought that the specific properties
of input synapses are responsible for rapid recruitment. However, a potential
contribution of active dendritic conductances has not been addressed. We combined
confocal imaging and patch-clamp techniques to obtain simultaneous somatodendritic
recordings from BCs. Action potentials were initiated in the BC axon and backpropagated
into the dendrites with reduced amplitude and little activity dependence. These
properties were explained by a high K+ to Na+ conductance ratio in BC dendrites.
Computational analysis indicated that dendritic K+ channels convey unique integration
properties to BCs, leading to the rapid and temporally precise activation by excitatory
inputs.
author:
- first_name: Hua
full_name: Hua Hu
id: 4AC0145C-F248-11E8-B48F-1D18A9856A87
last_name: Hu
- first_name: Marco
full_name: Martina, Marco
last_name: Martina
- first_name: Peter M
full_name: Peter Jonas
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Hu H, Martina M, Jonas PM. Dendritic mechanisms underlying rapid synaptic activation
of fast-spiking hippocampal interneurons. Science. 2010;327(5961):52-58.
doi:10.1126/science.1177876
apa: Hu, H., Martina, M., & Jonas, P. M. (2010). Dendritic mechanisms underlying
rapid synaptic activation of fast-spiking hippocampal interneurons. Science.
American Association for the Advancement of Science. https://doi.org/10.1126/science.1177876
chicago: Hu, Hua, Marco Martina, and Peter M Jonas. “Dendritic Mechanisms Underlying
Rapid Synaptic Activation of Fast-Spiking Hippocampal Interneurons.” Science.
American Association for the Advancement of Science, 2010. https://doi.org/10.1126/science.1177876.
ieee: H. Hu, M. Martina, and P. M. Jonas, “Dendritic mechanisms underlying rapid
synaptic activation of fast-spiking hippocampal interneurons,” Science,
vol. 327, no. 5961. American Association for the Advancement of Science, pp. 52–8,
2010.
ista: Hu H, Martina M, Jonas PM. 2010. Dendritic mechanisms underlying rapid synaptic
activation of fast-spiking hippocampal interneurons. Science. 327(5961), 52–8.
mla: Hu, Hua, et al. “Dendritic Mechanisms Underlying Rapid Synaptic Activation
of Fast-Spiking Hippocampal Interneurons.” Science, vol. 327, no. 5961,
American Association for the Advancement of Science, 2010, pp. 52–58, doi:10.1126/science.1177876.
short: H. Hu, M. Martina, P.M. Jonas, Science 327 (2010) 52–8.
date_created: 2018-12-11T12:05:24Z
date_published: 2010-01-01T00:00:00Z
date_updated: 2021-01-12T07:52:30Z
day: '01'
doi: 10.1126/science.1177876
extern: 1
intvolume: ' 327'
issue: '5961'
month: '01'
page: 52 - 8
publication: Science
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '2381'
quality_controlled: 0
status: public
title: Dendritic mechanisms underlying rapid synaptic activation of fast-spiking hippocampal
interneurons
type: journal_article
volume: 327
year: '2010'
...
---
_id: '3831'
abstract:
- lang: eng
text: Fast-spiking, parvalbumin-expressing basket cells (BCs) play a key role in
feedforward and feedback inhibition in the hippocampus. However, the dendritic
mechanisms underlying rapid interneuron recruitment have remained unclear. To
quantitatively address this question, we developed detailed passive cable models
of BCs in the dentate gyrus based on dual somatic or somatodendritic recordings
and complete morphologic reconstructions. Both specific membrane capacitance and
axial resistivity were comparable to those of pyramidal neurons, but the average
somatodendritic specific membrane resistance (R(m)) was substantially lower in
BCs. Furthermore, R(m) was markedly nonuniform, being lowest in soma and proximal
dendrites, intermediate in distal dendrites, and highest in the axon. Thus, the
somatodendritic gradient of R(m) was the reverse of that in pyramidal neurons.
Further computational analysis revealed that these unique cable properties accelerate
the time course of synaptic potentials at the soma in response to fast inputs,
while boosting the efficacy of slow distal inputs. These properties will facilitate
both rapid phasic and efficient tonic activation of BCs in hippocampal microcircuits.
author:
- first_name: Anja
full_name: Norenberg, Anja
last_name: Norenberg
- first_name: Hua
full_name: Hua Hu
id: 4AC0145C-F248-11E8-B48F-1D18A9856A87
last_name: Hu
- first_name: Imre
full_name: Vida, Imre
last_name: Vida
- first_name: Marlene
full_name: Bartos, Marlene
last_name: Bartos
- first_name: Peter M
full_name: Peter Jonas
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Norenberg A, Hu H, Vida I, Bartos M, Jonas PM. Distinct nonuniform cable properties
optimize rapid and efficient activation of fast-spiking GABAergic interneurons.
PNAS. 2010;107(2):894-899. doi:10.1073/pnas.0910716107
apa: Norenberg, A., Hu, H., Vida, I., Bartos, M., & Jonas, P. M. (2010). Distinct
nonuniform cable properties optimize rapid and efficient activation of fast-spiking
GABAergic interneurons. PNAS. National Academy of Sciences. https://doi.org/10.1073/pnas.0910716107
chicago: Norenberg, Anja, Hua Hu, Imre Vida, Marlene Bartos, and Peter M Jonas.
“Distinct Nonuniform Cable Properties Optimize Rapid and Efficient Activation
of Fast-Spiking GABAergic Interneurons.” PNAS. National Academy of Sciences,
2010. https://doi.org/10.1073/pnas.0910716107.
ieee: A. Norenberg, H. Hu, I. Vida, M. Bartos, and P. M. Jonas, “Distinct nonuniform
cable properties optimize rapid and efficient activation of fast-spiking GABAergic
interneurons,” PNAS, vol. 107, no. 2. National Academy of Sciences, pp.
894–9, 2010.
ista: Norenberg A, Hu H, Vida I, Bartos M, Jonas PM. 2010. Distinct nonuniform cable
properties optimize rapid and efficient activation of fast-spiking GABAergic interneurons.
PNAS. 107(2), 894–9.
mla: Norenberg, Anja, et al. “Distinct Nonuniform Cable Properties Optimize Rapid
and Efficient Activation of Fast-Spiking GABAergic Interneurons.” PNAS,
vol. 107, no. 2, National Academy of Sciences, 2010, pp. 894–99, doi:10.1073/pnas.0910716107.
short: A. Norenberg, H. Hu, I. Vida, M. Bartos, P.M. Jonas, PNAS 107 (2010) 894–9.
date_created: 2018-12-11T12:05:24Z
date_published: 2010-01-01T00:00:00Z
date_updated: 2021-01-12T07:52:31Z
day: '01'
doi: 10.1073/pnas.0910716107
extern: 1
intvolume: ' 107'
issue: '2'
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2818894/#!po=4.16667
month: '01'
oa: 1
page: 894 - 9
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '2379'
quality_controlled: 0
status: public
title: Distinct nonuniform cable properties optimize rapid and efficient activation
of fast-spiking GABAergic interneurons
type: journal_article
volume: 107
year: '2010'
...