---
_id: '11863'
abstract:
- lang: eng
  text: "Suppose you buy a new laptop and, simply because you like it so much, you
    recommend it to friends, encouraging them to purchase it as well. What would be
    an adequate price for the vendor of the laptop to pay for your recommendation?\r\n\r\nPersonal
    recommendations like this are of considerable commercial interest, but unlike
    in sponsored search auctions there can be no truthful prices. Despite this \"lack
    of truthfulness\" the vendor of the product might still decide to pay you for
    recommendation e.g. because she wants to (i) provide you with an additional incentive
    to actually recommend her or to (ii) increase your satisfaction and/or brand loyalty.
    This leads us to investigate a pricing scheme based on the Shapley value [5] that
    satisfies certain \"axioms of fairness\". We find that it is vulnerable to manipulations
    and show how to overcome these difficulties using the anonymity-proof Shapley
    value of [4]."
article_processing_charge: No
author:
- first_name: Paul
  full_name: Dütting, Paul
  last_name: Dütting
- first_name: Monika H
  full_name: Henzinger, Monika H
  id: 540c9bbd-f2de-11ec-812d-d04a5be85630
  last_name: Henzinger
  orcid: 0000-0002-5008-6530
- first_name: Ingmar
  full_name: Weber, Ingmar
  last_name: Weber
citation:
  ama: 'Dütting P, Henzinger MH, Weber I. How much is your personal recommendation
    worth? In: <i>Proceedings of the 19th International Conference on World Wide Web
    </i>. Association for Computing Machinery; 2010:1085-1086. doi:<a href="https://doi.org/10.1145/1772690.1772816">10.1145/1772690.1772816</a>'
  apa: 'Dütting, P., Henzinger, M. H., &#38; Weber, I. (2010). How much is your personal
    recommendation worth? In <i>Proceedings of the 19th international conference on
    World wide web </i> (pp. 1085–1086). Raleigh, NC, United States: Association for
    Computing Machinery. <a href="https://doi.org/10.1145/1772690.1772816">https://doi.org/10.1145/1772690.1772816</a>'
  chicago: Dütting, Paul, Monika H Henzinger, and Ingmar Weber. “How Much Is Your
    Personal Recommendation Worth?” In <i>Proceedings of the 19th International Conference
    on World Wide Web </i>, 1085–86. Association for Computing Machinery, 2010. <a
    href="https://doi.org/10.1145/1772690.1772816">https://doi.org/10.1145/1772690.1772816</a>.
  ieee: P. Dütting, M. H. Henzinger, and I. Weber, “How much is your personal recommendation
    worth?,” in <i>Proceedings of the 19th international conference on World wide
    web </i>, Raleigh, NC, United States, 2010, pp. 1085–1086.
  ista: 'Dütting P, Henzinger MH, Weber I. 2010. How much is your personal recommendation
    worth? Proceedings of the 19th international conference on World wide web . WWW:
    International Conference on World Wide Web, 1085–1086.'
  mla: Dütting, Paul, et al. “How Much Is Your Personal Recommendation Worth?” <i>Proceedings
    of the 19th International Conference on World Wide Web </i>, Association for Computing
    Machinery, 2010, pp. 1085–86, doi:<a href="https://doi.org/10.1145/1772690.1772816">10.1145/1772690.1772816</a>.
  short: P. Dütting, M.H. Henzinger, I. Weber, in:, Proceedings of the 19th International
    Conference on World Wide Web , Association for Computing Machinery, 2010, pp.
    1085–1086.
conference:
  end_date: 2010-04-30
  location: Raleigh, NC, United States
  name: 'WWW: International Conference on World Wide Web'
  start_date: 2010-04-26
date_created: 2022-08-16T09:00:41Z
date_published: 2010-04-01T00:00:00Z
date_updated: 2023-02-17T10:14:10Z
day: '01'
doi: 10.1145/1772690.1772816
extern: '1'
language:
- iso: eng
month: '04'
oa_version: None
page: 1085-1086
publication: 'Proceedings of the 19th international conference on World wide web '
publication_identifier:
  isbn:
  - '9781605587998'
publication_status: published
publisher: Association for Computing Machinery
quality_controlled: '1'
scopus_import: '1'
status: public
title: How much is your personal recommendation worth?
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2010'
...
---
_id: '11885'
abstract:
- lang: eng
  text: Over the last years the h-index has gained popularity as a measure for comparing
    the impact of scientists. We investigate if ranking according to the h-index is
    stable with respect to (i) different choices of citation databases, (ii) normalizing
    citation counts by the number of authors or by removing self-citations, (iii)
    small amounts of noise created by randomly removing citations or publications
    and (iv) small changes in the definition of the index. In experiments for 5,283
    computer scientists and 1,354 physicists we show that although the ranking of
    the h-index is stable under most of these changes, it is unstable when different
    databases are used. Therefore, comparisons based on the h-index should only be
    trusted when the rankings of multiple citation databases agree.
article_processing_charge: No
article_type: original
author:
- first_name: Monika H
  full_name: Henzinger, Monika H
  id: 540c9bbd-f2de-11ec-812d-d04a5be85630
  last_name: Henzinger
  orcid: 0000-0002-5008-6530
- first_name: Jacob
  full_name: Suñol, Jacob
  last_name: Suñol
- first_name: Ingmar
  full_name: Weber, Ingmar
  last_name: Weber
citation:
  ama: Henzinger MH, Suñol J, Weber I. The stability of the h-index. <i>Scientometrics</i>.
    2010;84(2):465-479. doi:<a href="https://doi.org/10.1007/s11192-009-0098-7">10.1007/s11192-009-0098-7</a>
  apa: Henzinger, M. H., Suñol, J., &#38; Weber, I. (2010). The stability of the h-index.
    <i>Scientometrics</i>. Springer Nature. <a href="https://doi.org/10.1007/s11192-009-0098-7">https://doi.org/10.1007/s11192-009-0098-7</a>
  chicago: Henzinger, Monika H, Jacob Suñol, and Ingmar Weber. “The Stability of the
    H-Index.” <i>Scientometrics</i>. Springer Nature, 2010. <a href="https://doi.org/10.1007/s11192-009-0098-7">https://doi.org/10.1007/s11192-009-0098-7</a>.
  ieee: M. H. Henzinger, J. Suñol, and I. Weber, “The stability of the h-index,” <i>Scientometrics</i>,
    vol. 84, no. 2. Springer Nature, pp. 465–479, 2010.
  ista: Henzinger MH, Suñol J, Weber I. 2010. The stability of the h-index. Scientometrics.
    84(2), 465–479.
  mla: Henzinger, Monika H., et al. “The Stability of the H-Index.” <i>Scientometrics</i>,
    vol. 84, no. 2, Springer Nature, 2010, pp. 465–79, doi:<a href="https://doi.org/10.1007/s11192-009-0098-7">10.1007/s11192-009-0098-7</a>.
  short: M.H. Henzinger, J. Suñol, I. Weber, Scientometrics 84 (2010) 465–479.
date_created: 2022-08-17T07:51:23Z
date_published: 2010-08-01T00:00:00Z
date_updated: 2023-02-17T14:09:51Z
day: '01'
doi: 10.1007/s11192-009-0098-7
extern: '1'
intvolume: '        84'
issue: '2'
language:
- iso: eng
month: '08'
oa_version: None
page: 465-479
publication: Scientometrics
publication_identifier:
  eissn:
  - 1588-2861
  issn:
  - 0138-9130
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: The stability of the h-index
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 84
year: '2010'
...
---
_id: '11975'
abstract:
- lang: eng
  text: A new method was developed for the quantitative analysis of steryl glycosides
    in biodiesel (fatty acid methyl esters). This method is much more sensitive than
    existing methods and has minimum limits of quantification of 50 μg/kg, compared
    to previously published minimum limits of quantification of about 15 mg/kg. The
    analysis is based on gas chromatography–mass spectroscopy determination of simple
    pre-treated and silylated samples via single ion monitoring at 147, 204, 217 m/z,
    which are specific ions for the silylated sugar moiety. Quantification was carried
    out using cholesteryl β-d-glucopyranoside as internal standard. The modified synthesis
    and purification of the internal standard is also presented as well as the characterization
    by NMR and mass spectroscopy. The advantage of the method compared with other
    approaches is the simplified sample preparation avoiding extra pre-treatment steps
    coupled with complete derivatization of the sugar hydroxyl groups by using N,O-bis(trimethylsilyl)acetamide
    with 5% trimethylchlorosilane as derivatization reagent. On the given conditions
    high recovery rates ≥89% can be obtained. Evaluation of lab specific variance
    and intermediate precision underline the robustness of the method which will be
    further assessed by Round robin tests.
article_processing_charge: No
article_type: original
author:
- first_name: Bartholomäus
  full_name: Pieber, Bartholomäus
  id: 93e5e5b2-0da6-11ed-8a41-af589a024726
  last_name: Pieber
  orcid: 0000-0001-8689-388X
- first_name: Sigurd
  full_name: Schober, Sigurd
  last_name: Schober
- first_name: Christoph
  full_name: Goebl, Christoph
  last_name: Goebl
- first_name: Martin
  full_name: Mittelbach, Martin
  last_name: Mittelbach
citation:
  ama: Pieber B, Schober S, Goebl C, Mittelbach M. Novel sensitive determination of
    steryl glycosides in biodiesel by gas chromatography-mass spectroscopy. <i>Journal
    of Chromatography A</i>. 2010;1217(42):6555-6561. doi:<a href="https://doi.org/10.1016/j.chroma.2010.08.006">10.1016/j.chroma.2010.08.006</a>
  apa: Pieber, B., Schober, S., Goebl, C., &#38; Mittelbach, M. (2010). Novel sensitive
    determination of steryl glycosides in biodiesel by gas chromatography-mass spectroscopy.
    <i>Journal of Chromatography A</i>. Elsevier. <a href="https://doi.org/10.1016/j.chroma.2010.08.006">https://doi.org/10.1016/j.chroma.2010.08.006</a>
  chicago: Pieber, Bartholomäus, Sigurd Schober, Christoph Goebl, and Martin Mittelbach.
    “Novel Sensitive Determination of Steryl Glycosides in Biodiesel by Gas Chromatography-Mass
    Spectroscopy.” <i>Journal of Chromatography A</i>. Elsevier, 2010. <a href="https://doi.org/10.1016/j.chroma.2010.08.006">https://doi.org/10.1016/j.chroma.2010.08.006</a>.
  ieee: B. Pieber, S. Schober, C. Goebl, and M. Mittelbach, “Novel sensitive determination
    of steryl glycosides in biodiesel by gas chromatography-mass spectroscopy,” <i>Journal
    of Chromatography A</i>, vol. 1217, no. 42. Elsevier, pp. 6555–6561, 2010.
  ista: Pieber B, Schober S, Goebl C, Mittelbach M. 2010. Novel sensitive determination
    of steryl glycosides in biodiesel by gas chromatography-mass spectroscopy. Journal
    of Chromatography A. 1217(42), 6555–6561.
  mla: Pieber, Bartholomäus, et al. “Novel Sensitive Determination of Steryl Glycosides
    in Biodiesel by Gas Chromatography-Mass Spectroscopy.” <i>Journal of Chromatography
    A</i>, vol. 1217, no. 42, Elsevier, 2010, pp. 6555–61, doi:<a href="https://doi.org/10.1016/j.chroma.2010.08.006">10.1016/j.chroma.2010.08.006</a>.
  short: B. Pieber, S. Schober, C. Goebl, M. Mittelbach, Journal of Chromatography
    A 1217 (2010) 6555–6561.
date_created: 2022-08-25T10:43:43Z
date_published: 2010-10-15T00:00:00Z
date_updated: 2023-02-21T10:09:59Z
day: '15'
doi: 10.1016/j.chroma.2010.08.006
extern: '1'
external_id:
  pmid:
  - '20846658'
intvolume: '      1217'
issue: '42'
language:
- iso: eng
month: '10'
oa_version: None
page: 6555-6561
pmid: 1
publication: Journal of Chromatography A
publication_identifier:
  issn:
  - 0021-9673
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Novel sensitive determination of steryl glycosides in biodiesel by gas chromatography-mass
  spectroscopy
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 1217
year: '2010'
...
---
_id: '12199'
abstract:
- lang: eng
  text: The four microsporangia of the flowering plant anther develop from archesporial
    cells in the L2 of the primordium. Within each microsporangium, developing microsporocytes
    are surrounded by concentric monolayers of tapetal, middle layer and endothecial
    cells. How this intricate array of tissues, each containing relatively few cells,
    is established in an organ possessing no formal meristems is poorly understood.
    We describe here the pivotal role of the LRR receptor kinase EXCESS MICROSPOROCYTES
    1 (EMS1) in forming the monolayer of tapetal nurse cells in Arabidopsis. Unusually
    for plants, tapetal cells are specified very early in development, and are subsequently
    stimulated to proliferate by a receptor-like kinase (RLK) complex that includes
    EMS1. Mutations in members of this EMS1 signalling complex and its putative ligand
    result in male-sterile plants in which tapetal initials fail to proliferate. Surprisingly,
    these cells continue to develop, isolated at the locular periphery. Mutant and
    wild-type microsporangia expand at similar rates and the ‘tapetal’ space at the
    periphery of mutant locules becomes occupied by microsporocytes. However, induction
    of late expression of EMS1 in the few tapetal initials in ems1 plants results
    in their proliferation to generate a functional tapetum, and this proliferation
    suppresses microsporocyte number. Our experiments also show that integrity of
    the tapetal monolayer is crucial for the maintenance of the polarity of divisions
    within it. This unexpected autonomy of the tapetal ‘lineage’ is discussed in the
    context of tissue development in complex plant organs, where constancy in size,
    shape and cell number is crucial.
acknowledgement: 'We thank the following for providing mutant lines and reagents:
  Hong Ma, De Ye, Sacco De Vries, and Rod Scott for providing the pA9::Barnase lines
  and information on A9 expression patterns. Carla Galinha and Paolo Piazza gave valuable
  help with in situ hybridisation and qRT-PCR, respectively, and we acknowledge Qing
  Zhang, Helen Prescott and Matthew Dicks for providing excellent technical assistance.
  We are indebted to Miltos Tsiantis and Angela Hay for helpful discussion, and the
  research was funded by Oxford University through a Clarendon Scholarship to X.F.,
  with additional financial support from Magdalen College (Oxford).'
article_processing_charge: No
article_type: original
author:
- first_name: Xiaoqi
  full_name: Feng, Xiaoqi
  id: e0164712-22ee-11ed-b12a-d80fcdf35958
  last_name: Feng
  orcid: 0000-0002-4008-1234
- first_name: Hugh G.
  full_name: Dickinson, Hugh G.
  last_name: Dickinson
citation:
  ama: Feng X, Dickinson HG. Tapetal cell fate, lineage and proliferation in the Arabidopsis
    anther. <i>Development</i>. 2010;137(14):2409-2416. doi:<a href="https://doi.org/10.1242/dev.049320">10.1242/dev.049320</a>
  apa: Feng, X., &#38; Dickinson, H. G. (2010). Tapetal cell fate, lineage and proliferation
    in the Arabidopsis anther. <i>Development</i>. The Company of Biologists. <a href="https://doi.org/10.1242/dev.049320">https://doi.org/10.1242/dev.049320</a>
  chicago: Feng, Xiaoqi, and Hugh G. Dickinson. “Tapetal Cell Fate, Lineage and Proliferation
    in the Arabidopsis Anther.” <i>Development</i>. The Company of Biologists, 2010.
    <a href="https://doi.org/10.1242/dev.049320">https://doi.org/10.1242/dev.049320</a>.
  ieee: X. Feng and H. G. Dickinson, “Tapetal cell fate, lineage and proliferation
    in the Arabidopsis anther,” <i>Development</i>, vol. 137, no. 14. The Company
    of Biologists, pp. 2409–2416, 2010.
  ista: Feng X, Dickinson HG. 2010. Tapetal cell fate, lineage and proliferation in
    the Arabidopsis anther. Development. 137(14), 2409–2416.
  mla: Feng, Xiaoqi, and Hugh G. Dickinson. “Tapetal Cell Fate, Lineage and Proliferation
    in the Arabidopsis Anther.” <i>Development</i>, vol. 137, no. 14, The Company
    of Biologists, 2010, pp. 2409–16, doi:<a href="https://doi.org/10.1242/dev.049320">10.1242/dev.049320</a>.
  short: X. Feng, H.G. Dickinson, Development 137 (2010) 2409–2416.
date_created: 2023-01-16T09:21:54Z
date_published: 2010-07-15T00:00:00Z
date_updated: 2023-05-08T10:57:11Z
day: '15'
department:
- _id: XiFe
doi: 10.1242/dev.049320
extern: '1'
external_id:
  pmid:
  - '20570940'
intvolume: '       137'
issue: '14'
keyword:
- Developmental Biology
- Molecular Biology
- Anther Tapetum
- Arabidopsis
- Cell Fate Establishment
- EMS1
- Reproductive Cell Lineage
language:
- iso: eng
month: '07'
oa_version: None
page: 2409-2416
pmid: 1
publication: Development
publication_identifier:
  issn:
  - 1477-9129
  - 0950-1991
publication_status: published
publisher: The Company of Biologists
quality_controlled: '1'
scopus_import: '1'
status: public
title: Tapetal cell fate, lineage and proliferation in the Arabidopsis anther
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 137
year: '2010'
...
---
_id: '12200'
abstract:
- lang: eng
  text: Key steps in the evolution of the angiosperm anther include the patterning
    of the concentrically organized microsporangium and the incorporation of four
    such microsporangia into a leaf-like structure. Mutant studies in the model plant
    Arabidopsis thaliana are leading to an increasingly accurate picture of (i) the
    cell lineages culminating in the different cell types present in the microsporangium
    (the microsporocytes, the tapetum, and the middle and endothecial layers), and
    (ii) some of the genes responsible for specifying their fates. However, the processes
    that confer polarity on the developing anther and position the microsporangia
    within it remain unclear. Certainly, data from a range of experimental strategies
    suggest that hormones play a central role in establishing polarity and the patterning
    of the anther initial, and may be responsible for locating the microsporangia.
    But the fact that microsporangia were originally positioned externally suggests
    that their development is likely to be autonomous, perhaps with the reproductive
    cells generating signals controlling the growth and division of the investing
    anther epidermis. These possibilities are discussed in the context of the expression
    of genes which initiate and maintain male and female reproductive development,
    and in the perspective of our current views of anther evolution.
article_processing_charge: No
article_type: original
author:
- first_name: Xiaoqi
  full_name: Feng, Xiaoqi
  id: e0164712-22ee-11ed-b12a-d80fcdf35958
  last_name: Feng
  orcid: 0000-0002-4008-1234
- first_name: Hugh G.
  full_name: Dickinson, Hugh G.
  last_name: Dickinson
citation:
  ama: Feng X, Dickinson HG. Cell–cell interactions during patterning of the <i>Arabidopsis</i>
    anther. <i>Biochemical Society Transactions</i>. 2010;38(2):571-576. doi:<a href="https://doi.org/10.1042/bst0380571">10.1042/bst0380571</a>
  apa: Feng, X., &#38; Dickinson, H. G. (2010). Cell–cell interactions during patterning
    of the <i>Arabidopsis</i> anther. <i>Biochemical Society Transactions</i>. Portland
    Press Ltd. <a href="https://doi.org/10.1042/bst0380571">https://doi.org/10.1042/bst0380571</a>
  chicago: Feng, Xiaoqi, and Hugh G. Dickinson. “Cell–Cell Interactions during Patterning
    of the <i>Arabidopsis</i> Anther.” <i>Biochemical Society Transactions</i>. Portland
    Press Ltd., 2010. <a href="https://doi.org/10.1042/bst0380571">https://doi.org/10.1042/bst0380571</a>.
  ieee: X. Feng and H. G. Dickinson, “Cell–cell interactions during patterning of
    the <i>Arabidopsis</i> anther,” <i>Biochemical Society Transactions</i>, vol.
    38, no. 2. Portland Press Ltd., pp. 571–576, 2010.
  ista: Feng X, Dickinson HG. 2010. Cell–cell interactions during patterning of the
    <i>Arabidopsis</i> anther. Biochemical Society Transactions. 38(2), 571–576.
  mla: Feng, Xiaoqi, and Hugh G. Dickinson. “Cell–Cell Interactions during Patterning
    of the <i>Arabidopsis</i> Anther.” <i>Biochemical Society Transactions</i>, vol.
    38, no. 2, Portland Press Ltd., 2010, pp. 571–76, doi:<a href="https://doi.org/10.1042/bst0380571">10.1042/bst0380571</a>.
  short: X. Feng, H.G. Dickinson, Biochemical Society Transactions 38 (2010) 571–576.
date_created: 2023-01-16T09:22:18Z
date_published: 2010-03-22T00:00:00Z
date_updated: 2023-05-08T10:57:59Z
day: '22'
department:
- _id: XiFe
doi: 10.1042/bst0380571
extern: '1'
external_id:
  pmid:
  - '20298223'
intvolume: '        38'
issue: '2'
keyword:
- Biochemistry
- Anther Development
- Arabidopsis
- Cell Fate
- Microsporangium
- Polarity
- Receptor Kinase
language:
- iso: eng
month: '03'
oa_version: None
page: 571-576
pmid: 1
publication: Biochemical Society Transactions
publication_identifier:
  issn:
  - 0300-5127
  - 1470-8752
publication_status: published
publisher: Portland Press Ltd.
quality_controlled: '1'
scopus_import: '1'
status: public
title: Cell–cell interactions during patterning of the <i>Arabidopsis</i> anther
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 38
year: '2010'
...
---
_id: '12653'
abstract:
- lang: eng
  text: 'Daily streamflow from stations close to five Swiss glaciers is analyzed for
    trends with the Mann-Kendall test. We consider a common period of record (1974–2004)
    and longer periods based on data availability. The trend statistical significance
    is tested on annual and seasonal bases. We also examine changes in precipitation,
    temperature, and snow cover characteristics. Highly glacierized basins show statistically
    significant positive trends in annual streamflow caused by increasing streamflow
    in spring and summer. Trends are more numerous and stronger at lower and mid than
    at the upper quantiles. The basin characterized by lower glacier coverage, conversely,
    does not exhibit consistently statistically significant trends. Changes in precipitation
    are not sufficient to explain the observed streamflow trends. Air temperature
    sees an increase in mean, minimum, and maximum values at all sites. Variations
    in the seasonal snow accumulation and ablation process are evident. Solid precipitation
    is decreasing at all sites and trends may be due to a shift from snowfall into
    rainfall. Mean snow depth is also decreasing, and its duration is getting shorter
    because of a decrease in solid precipitation and enhanced melting. Trend magnitude
    attenuates with longer time series. Contrasting trends are detected for different
    subperiods in the last 70 years: statistically significant negative trends are
    observed in the periods 1944–1974 and 1954–1984 for Aletschgletscher, in contrast
    with the results for the common period. These trends are explained by different
    rates of ice volume changes, and the sign of trends is clearly related to phases
    of positive or negative glacier mass balance.'
article_number: W10522
article_processing_charge: No
article_type: original
author:
- first_name: Francesca
  full_name: Pellicciotti, Francesca
  id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
  last_name: Pellicciotti
- first_name: A.
  full_name: Bauder, A.
  last_name: Bauder
- first_name: M.
  full_name: Parola, M.
  last_name: Parola
citation:
  ama: Pellicciotti F, Bauder A, Parola M. Effect of glaciers on streamflow trends
    in the Swiss Alps. <i>Water Resources Research</i>. 2010;46(10). doi:<a href="https://doi.org/10.1029/2009wr009039">10.1029/2009wr009039</a>
  apa: Pellicciotti, F., Bauder, A., &#38; Parola, M. (2010). Effect of glaciers on
    streamflow trends in the Swiss Alps. <i>Water Resources Research</i>. American
    Geophysical Union. <a href="https://doi.org/10.1029/2009wr009039">https://doi.org/10.1029/2009wr009039</a>
  chicago: Pellicciotti, Francesca, A. Bauder, and M. Parola. “Effect of Glaciers
    on Streamflow Trends in the Swiss Alps.” <i>Water Resources Research</i>. American
    Geophysical Union, 2010. <a href="https://doi.org/10.1029/2009wr009039">https://doi.org/10.1029/2009wr009039</a>.
  ieee: F. Pellicciotti, A. Bauder, and M. Parola, “Effect of glaciers on streamflow
    trends in the Swiss Alps,” <i>Water Resources Research</i>, vol. 46, no. 10. American
    Geophysical Union, 2010.
  ista: Pellicciotti F, Bauder A, Parola M. 2010. Effect of glaciers on streamflow
    trends in the Swiss Alps. Water Resources Research. 46(10), W10522.
  mla: Pellicciotti, Francesca, et al. “Effect of Glaciers on Streamflow Trends in
    the Swiss Alps.” <i>Water Resources Research</i>, vol. 46, no. 10, W10522, American
    Geophysical Union, 2010, doi:<a href="https://doi.org/10.1029/2009wr009039">10.1029/2009wr009039</a>.
  short: F. Pellicciotti, A. Bauder, M. Parola, Water Resources Research 46 (2010).
date_created: 2023-02-20T08:18:27Z
date_published: 2010-10-01T00:00:00Z
date_updated: 2023-02-20T09:39:29Z
day: '01'
doi: 10.1029/2009wr009039
extern: '1'
intvolume: '        46'
issue: '10'
keyword:
- Water Science and Technology
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1029/2009WR009039
month: '10'
oa: 1
oa_version: Published Version
publication: Water Resources Research
publication_identifier:
  eissn:
  - 1944-7973
  issn:
  - 0043-1397
publication_status: published
publisher: American Geophysical Union
quality_controlled: '1'
scopus_import: '1'
status: public
title: Effect of glaciers on streamflow trends in the Swiss Alps
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 46
year: '2010'
...
---
_id: '1300'
abstract:
- lang: eng
  text: 'Motion vision is a major function of all visual systems, yet the underlying
    neural mechanisms and circuits are still elusive. In the lamina, the first optic
    neuropile of Drosophila melanogaster, photoreceptor signals split into five parallel
    pathways, L1-L5. Here we examine how these pathways contribute to visual motion
    detection by combining genetic block and reconstitution of neural activity in
    different lamina cell types with whole-cell recordings from downstream motion-sensitive
    neurons. We find reduced responses to moving gratings if L1 or L2 is blocked;
    however, reconstitution of photoreceptor input to only L1 or L2 results in wild-type
    responses. Thus, the first experiment indicates the necessity of both pathways,
    whereas the second indicates sufficiency of each single pathway. This contradiction
    can be explained by electrical coupling between L1 and L2, allowing for activation
    of both pathways even when only one of them receives photoreceptor input. A fundamental
    difference between the L1 pathway and the L2 pathway is uncovered when blocking
    L1 or L2 output while presenting moving edges of positive (ON) or negative (OFF)
    contrast polarity: blocking L1 eliminates the response to moving ON edges, whereas
    blocking L2 eliminates the response to moving OFF edges. Thus, similar to the
    segregation of photoreceptor signals in ON and OFF bipolar cell pathways in the
    vertebrate retina, photoreceptor signals segregate into ON-L1 and OFF-L2 channels
    in the lamina of Drosophila.'
author:
- first_name: Maximilian A
  full_name: Maximilian Jösch
  id: 2BD278E6-F248-11E8-B48F-1D18A9856A87
  last_name: Jösch
  orcid: 0000-0002-3937-1330
- first_name: Bettina
  full_name: Schnell, Bettina
  last_name: Schnell
- first_name: Shamprasad
  full_name: Raghu, Shamprasad V
  last_name: Raghu
- first_name: Dierk
  full_name: Reiff, Dierk F
  last_name: Reiff
- first_name: Alexander
  full_name: Borst, Alexander
  last_name: Borst
citation:
  ama: Jösch MA, Schnell B, Raghu S, Reiff D, Borst A. ON and off pathways in Drosophila
    motion vision. <i>Nature</i>. 2010;468(7321):300-304. doi:<a href="https://doi.org/10.1038/nature09545">10.1038/nature09545</a>
  apa: Jösch, M. A., Schnell, B., Raghu, S., Reiff, D., &#38; Borst, A. (2010). ON
    and off pathways in Drosophila motion vision. <i>Nature</i>. Nature Publishing
    Group. <a href="https://doi.org/10.1038/nature09545">https://doi.org/10.1038/nature09545</a>
  chicago: Jösch, Maximilian A, Bettina Schnell, Shamprasad Raghu, Dierk Reiff, and
    Alexander Borst. “ON and off Pathways in Drosophila Motion Vision.” <i>Nature</i>.
    Nature Publishing Group, 2010. <a href="https://doi.org/10.1038/nature09545">https://doi.org/10.1038/nature09545</a>.
  ieee: M. A. Jösch, B. Schnell, S. Raghu, D. Reiff, and A. Borst, “ON and off pathways
    in Drosophila motion vision,” <i>Nature</i>, vol. 468, no. 7321. Nature Publishing
    Group, pp. 300–304, 2010.
  ista: Jösch MA, Schnell B, Raghu S, Reiff D, Borst A. 2010. ON and off pathways
    in Drosophila motion vision. Nature. 468(7321), 300–304.
  mla: Jösch, Maximilian A., et al. “ON and off Pathways in Drosophila Motion Vision.”
    <i>Nature</i>, vol. 468, no. 7321, Nature Publishing Group, 2010, pp. 300–04,
    doi:<a href="https://doi.org/10.1038/nature09545">10.1038/nature09545</a>.
  short: M.A. Jösch, B. Schnell, S. Raghu, D. Reiff, A. Borst, Nature 468 (2010) 300–304.
date_created: 2018-12-11T11:51:14Z
date_published: 2010-11-11T00:00:00Z
date_updated: 2021-01-12T06:49:44Z
day: '11'
doi: 10.1038/nature09545
extern: 1
intvolume: '       468'
issue: '7321'
month: '11'
page: 300 - 304
publication: Nature
publication_status: published
publisher: Nature Publishing Group
publist_id: '5970'
quality_controlled: 0
status: public
title: ON and off pathways in Drosophila motion vision
type: journal_article
volume: 468
year: '2010'
...
---
_id: '1301'
abstract:
- lang: eng
  text: Motion vision is essential for navigating through the environment. Due to
    its genetic amenability, the fruit fly Drosophila has been serving for a lengthy
    period as a model organism for studying optomotor behavior as elicited by large-field
    horizontal motion. However, the neurons underlying the control of this behavior
    have not been studied in Drosophila so far. Here we report the first whole cell
    recordings from three cells of the horizontal system (HSN, HSE, and HSS) in the
    lobula plate of Drosophila. All three HS cells are tuned to large-field horizontal
    motion in a direction-selective way; they become excited by front-to-back motion
    and inhibited by back-to-front motion in the ipsilateral field of view. The response
    properties of HS cells such as contrast and velocity dependence are in accordance
    with the correlation-type model of motion detection. Neurobiotin injection suggests
    extensive coupling among ipsilateral HS cells and additional coupling to tangential
    cells that have their dendrites in the contralateral hemisphere of the brain.
    This connectivity scheme accounts for the complex layout of their receptive fields
    and explains their sensitivity both to ipsilateral and to contralateral motion.
    Thus the main response properties of Drosophila HS cells are strikingly similar
    to the responses of their counterparts in the blowfly Calliphora, although we
    found substantial differences with respect to their dendritic structure and connectivity.
    This long-awaited functional characterization of HS cells in Drosophila provides
    the basis for the future dissection of optomotor behavior and the underlying neural
    circuitry by combining genetics, physiology, and behavior.
acknowledgement: This work was supported by the Max-Planck-Society and by a Human
  Frontier Science Program grant to K. Ito, A. Borst, and B. Nelson.
article_processing_charge: No
article_type: original
author:
- first_name: Bettina
  full_name: Schnell, Bettina
  last_name: Schnell
- first_name: Maximilian A
  full_name: Jösch, Maximilian A
  id: 2BD278E6-F248-11E8-B48F-1D18A9856A87
  last_name: Jösch
  orcid: 0000-0002-3937-1330
- first_name: Friedrich
  full_name: Förstner, Friedrich
  last_name: Förstner
- first_name: Shamprasad
  full_name: Raghu, Shamprasad
  last_name: Raghu
- first_name: Hideo
  full_name: Otsuna, Hideo
  last_name: Otsuna
- first_name: Kei
  full_name: Ito, Kei
  last_name: Ito
- first_name: Alexander
  full_name: Borst, Alexander
  last_name: Borst
- first_name: Dierk
  full_name: Reiff, Dierk
  last_name: Reiff
citation:
  ama: Schnell B, Jösch MA, Förstner F, et al. Processing of horizontal optic flow
    in three visual interneurons of the Drosophila brain. <i>Journal of Neurophysiology</i>.
    2010;103(3):1646-1657. doi:<a href="https://doi.org/10.1152/jn.00950.2009">10.1152/jn.00950.2009</a>
  apa: Schnell, B., Jösch, M. A., Förstner, F., Raghu, S., Otsuna, H., Ito, K., …
    Reiff, D. (2010). Processing of horizontal optic flow in three visual interneurons
    of the Drosophila brain. <i>Journal of Neurophysiology</i>. American Physiological
    Society. <a href="https://doi.org/10.1152/jn.00950.2009">https://doi.org/10.1152/jn.00950.2009</a>
  chicago: Schnell, Bettina, Maximilian A Jösch, Friedrich Förstner, Shamprasad Raghu,
    Hideo Otsuna, Kei Ito, Alexander Borst, and Dierk Reiff. “Processing of Horizontal
    Optic Flow in Three Visual Interneurons of the Drosophila Brain.” <i>Journal of
    Neurophysiology</i>. American Physiological Society, 2010. <a href="https://doi.org/10.1152/jn.00950.2009">https://doi.org/10.1152/jn.00950.2009</a>.
  ieee: B. Schnell <i>et al.</i>, “Processing of horizontal optic flow in three visual
    interneurons of the Drosophila brain,” <i>Journal of Neurophysiology</i>, vol.
    103, no. 3. American Physiological Society, pp. 1646–1657, 2010.
  ista: Schnell B, Jösch MA, Förstner F, Raghu S, Otsuna H, Ito K, Borst A, Reiff
    D. 2010. Processing of horizontal optic flow in three visual interneurons of the
    Drosophila brain. Journal of Neurophysiology. 103(3), 1646–1657.
  mla: Schnell, Bettina, et al. “Processing of Horizontal Optic Flow in Three Visual
    Interneurons of the Drosophila Brain.” <i>Journal of Neurophysiology</i>, vol.
    103, no. 3, American Physiological Society, 2010, pp. 1646–57, doi:<a href="https://doi.org/10.1152/jn.00950.2009">10.1152/jn.00950.2009</a>.
  short: B. Schnell, M.A. Jösch, F. Förstner, S. Raghu, H. Otsuna, K. Ito, A. Borst,
    D. Reiff, Journal of Neurophysiology 103 (2010) 1646–1657.
date_created: 2018-12-11T11:51:14Z
date_published: 2010-03-01T00:00:00Z
date_updated: 2021-01-12T06:49:44Z
day: '01'
doi: 10.1152/jn.00950.2009
extern: '1'
external_id:
  pmid:
  - '20089816'
intvolume: '       103'
issue: '3'
language:
- iso: eng
month: '03'
oa_version: None
page: 1646 - 1657
pmid: 1
publication: Journal of Neurophysiology
publication_identifier:
  eissn:
  - 1522-1598
  issn:
  - ' 0022-3077'
publication_status: published
publisher: American Physiological Society
publist_id: '5971'
quality_controlled: '1'
status: public
title: Processing of horizontal optic flow in three visual interneurons of the Drosophila
  brain
type: journal_article
user_id: D865714E-FA4E-11E9-B85B-F5C5E5697425
volume: 103
year: '2010'
...
---
_id: '9764'
article_processing_charge: No
author:
- first_name: Ulises
  full_name: Rosas, Ulises
  last_name: Rosas
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Lucy
  full_name: Copsey, Lucy
  last_name: Copsey
- first_name: Pierre
  full_name: Barbier De Reuille, Pierre
  last_name: Barbier De Reuille
- first_name: Enrico
  full_name: Coen, Enrico
  last_name: Coen
citation:
  ama: Rosas U, Barton NH, Copsey L, Barbier De Reuille P, Coen E. Heterosis and the
    drift load. 2010. doi:<a href="https://doi.org/10.1371/journal.pbio.1000429.s003">10.1371/journal.pbio.1000429.s003</a>
  apa: Rosas, U., Barton, N. H., Copsey, L., Barbier De Reuille, P., &#38; Coen, E.
    (2010). Heterosis and the drift load. Public Library of Science. <a href="https://doi.org/10.1371/journal.pbio.1000429.s003">https://doi.org/10.1371/journal.pbio.1000429.s003</a>
  chicago: Rosas, Ulises, Nicholas H Barton, Lucy Copsey, Pierre Barbier De Reuille,
    and Enrico Coen. “Heterosis and the Drift Load.” Public Library of Science, 2010.
    <a href="https://doi.org/10.1371/journal.pbio.1000429.s003">https://doi.org/10.1371/journal.pbio.1000429.s003</a>.
  ieee: U. Rosas, N. H. Barton, L. Copsey, P. Barbier De Reuille, and E. Coen, “Heterosis
    and the drift load.” Public Library of Science, 2010.
  ista: Rosas U, Barton NH, Copsey L, Barbier De Reuille P, Coen E. 2010. Heterosis
    and the drift load, Public Library of Science, <a href="https://doi.org/10.1371/journal.pbio.1000429.s003">10.1371/journal.pbio.1000429.s003</a>.
  mla: Rosas, Ulises, et al. <i>Heterosis and the Drift Load</i>. Public Library of
    Science, 2010, doi:<a href="https://doi.org/10.1371/journal.pbio.1000429.s003">10.1371/journal.pbio.1000429.s003</a>.
  short: U. Rosas, N.H. Barton, L. Copsey, P. Barbier De Reuille, E. Coen, (2010).
date_created: 2021-08-02T09:45:39Z
date_published: 2010-07-20T00:00:00Z
date_updated: 2023-02-23T11:42:17Z
day: '20'
department:
- _id: NiBa
doi: 10.1371/journal.pbio.1000429.s003
month: '07'
oa_version: Published Version
publisher: Public Library of Science
related_material:
  record:
  - id: '3779'
    relation: used_in_publication
    status: public
status: public
title: Heterosis and the drift load
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2010'
...
---
_id: '3402'
abstract:
- lang: eng
  text: Model checking transactional memories (TMs) is difficult because of the unbounded
    number, length, and delay of concurrent transactions, as well as the unbounded
    size of the memory. We show that, under certain conditions satisfied by most TMs
    we know of, the model checking problem can be reduced to a finite-state problem,
    and we illustrate the use of the method by proving the correctness of several
    TMs, including two-phase locking, DSTM, and TL2. The safety properties we consider
    include strict serializability and opacity; the liveness properties include obstruction
    freedom, livelock freedom, and wait freedom. Our main contribution lies in the
    structure of the proofs, which are largely automated and not restricted to the
    TMs mentioned above. In a first step we show that every TM that enjoys certain
    structural properties either violates a requirement on some program with two threads
    and two shared variables, or satisfies the requirement on all programs. In the
    second step, we use a model checker to prove the requirement for the TM applied
    to a most general program with two threads and two variables. In the safety case,
    the model checker checks language inclusion between two finite-state transition
    systems, a nondeterministic transition system representing the given TM applied
    to a most general program, and a deterministic transition system representing
    a most liberal safe TM applied to the same program. The given TM transition system
    is nondeterministic because a TM can be used with different contention managers,
    which resolve conflicts differently. In the liveness case, the model checker analyzes
    fairness conditions on the given TM transition system.
acknowledgement: This research was supported by the Swiss National Science Foundation.
  This paper is an extended and revised version of our previous work on model checking
  transactional memories.
author:
- first_name: Rachid
  full_name: Guerraoui, Rachid
  last_name: Guerraoui
- first_name: Thomas A
  full_name: Thomas Henzinger
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
- first_name: Vasu
  full_name: Vasu Singh
  id: 4DAE2708-F248-11E8-B48F-1D18A9856A87
  last_name: Singh
citation:
  ama: Guerraoui R, Henzinger TA, Singh V. Model checking transactional memories.
    <i>Distributed Computing</i>. 2010;22(3):129-145. doi:<a href="https://doi.org/10.1007/s00446-009-0092-6">10.1007/s00446-009-0092-6</a>
  apa: Guerraoui, R., Henzinger, T. A., &#38; Singh, V. (2010). Model checking transactional
    memories. <i>Distributed Computing</i>. Springer. <a href="https://doi.org/10.1007/s00446-009-0092-6">https://doi.org/10.1007/s00446-009-0092-6</a>
  chicago: Guerraoui, Rachid, Thomas A Henzinger, and Vasu Singh. “Model Checking
    Transactional Memories.” <i>Distributed Computing</i>. Springer, 2010. <a href="https://doi.org/10.1007/s00446-009-0092-6">https://doi.org/10.1007/s00446-009-0092-6</a>.
  ieee: R. Guerraoui, T. A. Henzinger, and V. Singh, “Model checking transactional
    memories,” <i>Distributed Computing</i>, vol. 22, no. 3. Springer, pp. 129–145,
    2010.
  ista: Guerraoui R, Henzinger TA, Singh V. 2010. Model checking transactional memories.
    Distributed Computing. 22(3), 129–145.
  mla: Guerraoui, Rachid, et al. “Model Checking Transactional Memories.” <i>Distributed
    Computing</i>, vol. 22, no. 3, Springer, 2010, pp. 129–45, doi:<a href="https://doi.org/10.1007/s00446-009-0092-6">10.1007/s00446-009-0092-6</a>.
  short: R. Guerraoui, T.A. Henzinger, V. Singh, Distributed Computing 22 (2010) 129–145.
date_created: 2018-12-11T12:03:08Z
date_published: 2010-03-01T00:00:00Z
date_updated: 2021-01-12T07:43:14Z
day: '01'
doi: 10.1007/s00446-009-0092-6
extern: 1
intvolume: '        22'
issue: '3'
main_file_link:
- open_access: '0'
  url: http://infoscience.epfl.ch/record/117513/files/PLDI_paper.pdf
month: '03'
page: 129 - 145
publication: Distributed Computing
publication_status: published
publisher: Springer
publist_id: '3000'
pubrep_id: '74'
quality_controlled: 0
status: public
title: Model checking transactional memories
type: journal_article
volume: 22
year: '2010'
...
---
_id: '3403'
abstract:
- lang: eng
  text: Rate remapping is a conjunctive code that potentially enables hippocampal
    place cells to jointly represent spatial and nonspatial information. In this issue
    of Neuron, Rennó-Costa et al. introduce a theoretical model wherein the convergence
    of the medial and lateral entorhinal excitatory inputs, combined with local inhibition,
    explains hippocampal rate remapping. © 2010 Elsevier Inc.
author:
- first_name: Barty
  full_name: Pleydell-Bouverie, Barty
  last_name: Pleydell Bouverie
- first_name: Jozsef L
  full_name: Jozsef Csicsvari
  id: 3FA14672-F248-11E8-B48F-1D18A9856A87
  last_name: Csicsvari
  orcid: 0000-0002-5193-4036
citation:
  ama: 'Pleydell Bouverie B, Csicsvari JL. Rate remapping: When the code goes beyond
    space (preview). <i>Neuron</i>. 2010;68(6):1015-1016. doi:<a href="https://doi.org/10.1016/j.neuron.2010.12.011">10.1016/j.neuron.2010.12.011</a>'
  apa: 'Pleydell Bouverie, B., &#38; Csicsvari, J. L. (2010). Rate remapping: When
    the code goes beyond space (preview). <i>Neuron</i>. Elsevier. <a href="https://doi.org/10.1016/j.neuron.2010.12.011">https://doi.org/10.1016/j.neuron.2010.12.011</a>'
  chicago: 'Pleydell Bouverie, Barty, and Jozsef L Csicsvari. “Rate Remapping: When
    the Code Goes beyond Space (Preview).” <i>Neuron</i>. Elsevier, 2010. <a href="https://doi.org/10.1016/j.neuron.2010.12.011">https://doi.org/10.1016/j.neuron.2010.12.011</a>.'
  ieee: 'B. Pleydell Bouverie and J. L. Csicsvari, “Rate remapping: When the code
    goes beyond space (preview),” <i>Neuron</i>, vol. 68, no. 6. Elsevier, pp. 1015–1016,
    2010.'
  ista: 'Pleydell Bouverie B, Csicsvari JL. 2010. Rate remapping: When the code goes
    beyond space (preview). Neuron. 68(6), 1015–1016.'
  mla: 'Pleydell Bouverie, Barty, and Jozsef L. Csicsvari. “Rate Remapping: When the
    Code Goes beyond Space (Preview).” <i>Neuron</i>, vol. 68, no. 6, Elsevier, 2010,
    pp. 1015–16, doi:<a href="https://doi.org/10.1016/j.neuron.2010.12.011">10.1016/j.neuron.2010.12.011</a>.'
  short: B. Pleydell Bouverie, J.L. Csicsvari, Neuron 68 (2010) 1015–1016.
date_created: 2018-12-11T12:03:08Z
date_published: 2010-12-22T00:00:00Z
date_updated: 2019-05-10T12:19:51Z
day: '22'
doi: 10.1016/j.neuron.2010.12.011
extern: 1
intvolume: '        68'
issue: '6'
month: '12'
page: 1015 - 1016
publication: Neuron
publication_status: published
publisher: Elsevier
publist_id: '2999'
quality_controlled: 0
status: public
title: 'Rate remapping: When the code goes beyond space (preview)'
type: review
volume: 68
year: '2010'
...
---
_id: '3406'
abstract:
- lang: eng
  text: The impact of structural biology on the design of ligands (agonists, antagonists
    and modulators) for ionotropic glutamate receptors is reviewed.
author:
- first_name: Philipp
  full_name: Stawski, Philipp
  last_name: Stawski
- first_name: Harald L
  full_name: Harald Janovjak
  id: 33BA6C30-F248-11E8-B48F-1D18A9856A87
  last_name: Janovjak
  orcid: 0000-0002-8023-9315
- first_name: Dirk
  full_name: Trauner, Dirk
  last_name: Trauner
citation:
  ama: 'Stawski P, Janovjak HL, Trauner D. Pharmacology of ionotropic glutamate receptors:
    a structural perspective. <i>Bioorganic and Medicinal Chemistry</i>. 2010;18(22):7759-7772.
    doi:<a href="https://doi.org/10.1016/j.bmc.2010.09.012">10.1016/j.bmc.2010.09.012</a>'
  apa: 'Stawski, P., Janovjak, H. L., &#38; Trauner, D. (2010). Pharmacology of ionotropic
    glutamate receptors: a structural perspective. <i>Bioorganic and Medicinal Chemistry</i>.
    Elsevier. <a href="https://doi.org/10.1016/j.bmc.2010.09.012">https://doi.org/10.1016/j.bmc.2010.09.012</a>'
  chicago: 'Stawski, Philipp, Harald L Janovjak, and Dirk Trauner. “Pharmacology of
    Ionotropic Glutamate Receptors: A Structural Perspective.” <i>Bioorganic and Medicinal
    Chemistry</i>. Elsevier, 2010. <a href="https://doi.org/10.1016/j.bmc.2010.09.012">https://doi.org/10.1016/j.bmc.2010.09.012</a>.'
  ieee: 'P. Stawski, H. L. Janovjak, and D. Trauner, “Pharmacology of ionotropic glutamate
    receptors: a structural perspective,” <i>Bioorganic and Medicinal Chemistry</i>,
    vol. 18, no. 22. Elsevier, pp. 7759–7772, 2010.'
  ista: 'Stawski P, Janovjak HL, Trauner D. 2010. Pharmacology of ionotropic glutamate
    receptors: a structural perspective. Bioorganic and Medicinal Chemistry. 18(22),
    7759–7772.'
  mla: 'Stawski, Philipp, et al. “Pharmacology of Ionotropic Glutamate Receptors:
    A Structural Perspective.” <i>Bioorganic and Medicinal Chemistry</i>, vol. 18,
    no. 22, Elsevier, 2010, pp. 7759–72, doi:<a href="https://doi.org/10.1016/j.bmc.2010.09.012">10.1016/j.bmc.2010.09.012</a>.'
  short: P. Stawski, H.L. Janovjak, D. Trauner, Bioorganic and Medicinal Chemistry
    18 (2010) 7759–7772.
date_created: 2018-12-11T12:03:10Z
date_published: 2010-11-15T00:00:00Z
date_updated: 2019-04-26T07:22:27Z
day: '15'
doi: 10.1016/j.bmc.2010.09.012
extern: 1
intvolume: '        18'
issue: '22'
month: '11'
page: 7759 - 7772
publication: Bioorganic and Medicinal Chemistry
publication_status: published
publisher: Elsevier
publist_id: '2996'
quality_controlled: 0
status: public
title: 'Pharmacology of ionotropic glutamate receptors: a structural perspective'
type: review
volume: 18
year: '2010'
...
---
_id: '3407'
abstract:
- lang: eng
  text: Genetically targeted light-activated ion channels and pumps make it possible
    to determine the role of specific neurons in neuronal circuits, information processing
    and behavior. We developed a K+-selective ionotropic glutamate receptor that reversibly
    inhibits neuronal activity in response to light in dissociated neurons and brain
    slice and also reversibly suppresses behavior in zebrafish. The receptor is a
    chimera of the pore region of a K+-selective bacterial glutamate receptor and
    the ligand-binding domain of a light-gated mammalian kainate receptor. This hyperpolarizing
    light-gated channel, HyLighter, is turned on by a brief light pulse at one wavelength
    and turned off by a pulse at a second wavelength. The control is obtained at moderate
    intensity. After optical activation, the photocurrent and optical silencing of
    activity persists in the dark for extended periods. The low light requirement
    and bi-stability of HyLighter represent advantages for the dissection of neural
    circuitry.
author:
- first_name: Harald L
  full_name: Harald Janovjak
  id: 33BA6C30-F248-11E8-B48F-1D18A9856A87
  last_name: Janovjak
  orcid: 0000-0002-8023-9315
- first_name: Stephanie
  full_name: Szobota, Stephanie
  last_name: Szobota
- first_name: Claire
  full_name: Wyart, Claire
  last_name: Wyart
- first_name: Dirk
  full_name: Trauner, Dirk
  last_name: Trauner
- first_name: Ehud
  full_name: Isacoff, Ehud Y
  last_name: Isacoff
citation:
  ama: Janovjak HL, Szobota S, Wyart C, Trauner D, Isacoff E. A light-gated, potassium-selective
    glutamate receptor for the optical inhibition of neuronal firing. <i>Nature Neuroscience</i>.
    2010;13:1027-1032. doi:<a href="https://doi.org/10.1038/nn.2589">10.1038/nn.2589</a>
  apa: Janovjak, H. L., Szobota, S., Wyart, C., Trauner, D., &#38; Isacoff, E. (2010).
    A light-gated, potassium-selective glutamate receptor for the optical inhibition
    of neuronal firing. <i>Nature Neuroscience</i>. Nature Publishing Group. <a href="https://doi.org/10.1038/nn.2589">https://doi.org/10.1038/nn.2589</a>
  chicago: Janovjak, Harald L, Stephanie Szobota, Claire Wyart, Dirk Trauner, and
    Ehud Isacoff. “A Light-Gated, Potassium-Selective Glutamate Receptor for the Optical
    Inhibition of Neuronal Firing.” <i>Nature Neuroscience</i>. Nature Publishing
    Group, 2010. <a href="https://doi.org/10.1038/nn.2589">https://doi.org/10.1038/nn.2589</a>.
  ieee: H. L. Janovjak, S. Szobota, C. Wyart, D. Trauner, and E. Isacoff, “A light-gated,
    potassium-selective glutamate receptor for the optical inhibition of neuronal
    firing,” <i>Nature Neuroscience</i>, vol. 13. Nature Publishing Group, pp. 1027–1032,
    2010.
  ista: Janovjak HL, Szobota S, Wyart C, Trauner D, Isacoff E. 2010. A light-gated,
    potassium-selective glutamate receptor for the optical inhibition of neuronal
    firing. Nature Neuroscience. 13, 1027–1032.
  mla: Janovjak, Harald L., et al. “A Light-Gated, Potassium-Selective Glutamate Receptor
    for the Optical Inhibition of Neuronal Firing.” <i>Nature Neuroscience</i>, vol.
    13, Nature Publishing Group, 2010, pp. 1027–32, doi:<a href="https://doi.org/10.1038/nn.2589">10.1038/nn.2589</a>.
  short: H.L. Janovjak, S. Szobota, C. Wyart, D. Trauner, E. Isacoff, Nature Neuroscience
    13 (2010) 1027–1032.
date_created: 2018-12-11T12:03:10Z
date_published: 2010-06-27T00:00:00Z
date_updated: 2021-01-12T07:43:16Z
day: '27'
doi: 10.1038/nn.2589
extern: 1
intvolume: '        13'
month: '06'
page: 1027 - 1032
publication: Nature Neuroscience
publication_status: published
publisher: Nature Publishing Group
publist_id: '2995'
quality_controlled: 0
status: public
title: A light-gated, potassium-selective glutamate receptor for the optical inhibition
  of neuronal firing
type: journal_article
volume: 13
year: '2010'
...
---
_id: '3430'
abstract:
- lang: eng
  text: These are notes for a set of 7 two-hour lectures given at the 2010 Summer
    School on Quantitative Evolutionary and Comparative Genomics at OIST, Okinawa,
    Japan. The emphasis is on understanding how biological systems process information.
    We take a physicist's approach of looking for simple phenomenological descriptions
    that can address the questions of biological function without necessarily modeling
    all (mostly unknown) microscopic details; the example that is developed throughout
    the notes is transcriptional regulation in genetic regulatory networks. We present
    tools from information theory and statistical physics that can be used to analyze
    noisy nonlinear biological networks, and build generative and predictive models
    of regulatory processes.
author:
- first_name: Gasper
  full_name: Gasper Tkacik
  id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
  last_name: Tkacik
  orcid: 0000-0002-6699-1455
citation:
  ama: 'Tkačik G. Lecture notes for 2010 summer school on Quantitative Evolutionary
    and Comparative Genomics. In: Elsevier; 2010.'
  apa: Tkačik, G. (2010). Lecture notes for 2010 summer school on Quantitative Evolutionary
    and Comparative Genomics. Presented at the Summer School on Quantitative Evolutionary
    and Comparative Genomics, Elsevier.
  chicago: Tkačik, Gašper. “Lecture Notes for 2010 Summer School on Quantitative Evolutionary
    and Comparative Genomics.” Elsevier, 2010.
  ieee: G. Tkačik, “Lecture notes for 2010 summer school on Quantitative Evolutionary
    and Comparative Genomics,” presented at the Summer School on Quantitative Evolutionary
    and Comparative Genomics, 2010.
  ista: Tkačik G. 2010. Lecture notes for 2010 summer school on Quantitative Evolutionary
    and Comparative Genomics. Summer School on Quantitative Evolutionary and Comparative
    Genomics.
  mla: Tkačik, Gašper. <i>Lecture Notes for 2010 Summer School on Quantitative Evolutionary
    and Comparative Genomics</i>. Elsevier, 2010.
  short: G. Tkačik, in:, Elsevier, 2010.
conference:
  name: Summer School on Quantitative Evolutionary and Comparative Genomics
date_created: 2018-12-11T12:03:17Z
date_published: 2010-06-22T00:00:00Z
date_updated: 2021-01-12T07:43:25Z
day: '22'
extern: 1
main_file_link:
- open_access: '1'
  url: http://arxiv.org/pdf/1006.4291
month: '06'
oa: 1
publication_status: published
publisher: Elsevier
publist_id: '2970'
quality_controlled: 0
status: public
title: Lecture notes for 2010 summer school on Quantitative Evolutionary and Comparative
  Genomics
type: conference
year: '2010'
...
---
_id: '3441'
abstract:
- lang: eng
  text: The hippocampus is an important brain circuit for spatial memory and the spatially
    selective spiking of hippocampal neuronal assemblies is thought to provide a mnemonic
    representation of space. We found that remembering newly learnt goal locations
    required NMDA receptorĝ€&quot;dependent stabilization and enhanced reactivation
    of goal-related hippocampal assemblies. During spatial learning, place-related
    firing patterns in the CA1, but not CA3, region of the rat hippocampus were reorganized
    to represent new goal locations. Such reorganization did not occur when goals
    were marked by visual cues. The stabilization and successful retrieval of these
    newly acquired CA1 representations of behaviorally relevant places was NMDAR dependent
    and necessary for subsequent memory retention performance. Goal-related assembly
    patterns associated with sharp wave/ripple network oscillations, during both learning
    and subsequent rest periods, predicted memory performance. Together, these results
    suggest that the reorganization and reactivation of assembly firing patterns in
    the hippocampus represent the formation and expression of new spatial memory traces.
    © 2010 Nature America, Inc. All rights reserved.
acknowledgement: |
  Discussed in the News and Views section of the journal by Jeffery and Cacucci
author:
- first_name: David
  full_name: Dupret, David
  last_name: Dupret
- first_name: Joseph
  full_name: Joseph O'Neill
  id: 426376DC-F248-11E8-B48F-1D18A9856A87
  last_name: O'Neill
- first_name: Barty
  full_name: Pleydell-Bouverie, Barty
  last_name: Pleydell Bouverie
- first_name: Jozsef L
  full_name: Jozsef Csicsvari
  id: 3FA14672-F248-11E8-B48F-1D18A9856A87
  last_name: Csicsvari
  orcid: 0000-0002-5193-4036
citation:
  ama: Dupret D, O’Neill J, Pleydell Bouverie B, Csicsvari JL. The reorganization
    and reactivation of hippocampal maps predict spatial memory performance. <i>Nature
    Neuroscience</i>. 2010;13(8):995-1002. doi:<a href="https://doi.org/10.1038/nn.2599">10.1038/nn.2599</a>
  apa: Dupret, D., O’Neill, J., Pleydell Bouverie, B., &#38; Csicsvari, J. L. (2010).
    The reorganization and reactivation of hippocampal maps predict spatial memory
    performance. <i>Nature Neuroscience</i>. Nature Publishing Group. <a href="https://doi.org/10.1038/nn.2599">https://doi.org/10.1038/nn.2599</a>
  chicago: Dupret, David, Joseph O’Neill, Barty Pleydell Bouverie, and Jozsef L Csicsvari.
    “The Reorganization and Reactivation of Hippocampal Maps Predict Spatial Memory
    Performance.” <i>Nature Neuroscience</i>. Nature Publishing Group, 2010. <a href="https://doi.org/10.1038/nn.2599">https://doi.org/10.1038/nn.2599</a>.
  ieee: D. Dupret, J. O’Neill, B. Pleydell Bouverie, and J. L. Csicsvari, “The reorganization
    and reactivation of hippocampal maps predict spatial memory performance,” <i>Nature
    Neuroscience</i>, vol. 13, no. 8. Nature Publishing Group, pp. 995–1002, 2010.
  ista: Dupret D, O’Neill J, Pleydell Bouverie B, Csicsvari JL. 2010. The reorganization
    and reactivation of hippocampal maps predict spatial memory performance. Nature
    Neuroscience. 13(8), 995–1002.
  mla: Dupret, David, et al. “The Reorganization and Reactivation of Hippocampal Maps
    Predict Spatial Memory Performance.” <i>Nature Neuroscience</i>, vol. 13, no.
    8, Nature Publishing Group, 2010, pp. 995–1002, doi:<a href="https://doi.org/10.1038/nn.2599">10.1038/nn.2599</a>.
  short: D. Dupret, J. O’Neill, B. Pleydell Bouverie, J.L. Csicsvari, Nature Neuroscience
    13 (2010) 995–1002.
date_created: 2018-12-11T12:03:21Z
date_published: 2010-08-01T00:00:00Z
date_updated: 2021-01-12T07:43:29Z
day: '01'
doi: 10.1038/nn.2599
extern: 1
intvolume: '        13'
issue: '8'
month: '08'
page: 995 - 1002
publication: Nature Neuroscience
publication_status: published
publisher: Nature Publishing Group
publist_id: '2946'
quality_controlled: 0
status: public
title: The reorganization and reactivation of hippocampal maps predict spatial memory
  performance
type: journal_article
volume: 13
year: '2010'
...
---
_id: '3442'
abstract:
- lang: eng
  text: Episodic and spatial memories each involve the encoding of complex associations
    in hippocampal neuronal circuits. Such memory traces could be stabilised from
    short- to long-term forms by consolidation processes involving the 'reactivation'
    of the original network firing patterns during sleep and rest. Waking experience
    can be replayed in many different brain areas, but an important role for the hippocampus
    lies in the organisation of the 'reactivation' process. Emerging evidence suggests
    that sharp wave/ripple (SWR) events in the hippocampus could coordinate the reactivation
    of memory traces and direct their reinstatement in cortical circuits. Although
    the mechanisms remain uncertain, there is a growing consensus that such SWR-directed
    reactivation of brain-wide memory traces could underlie memory consolidation.
    © 2010 Elsevier Ltd.
author:
- first_name: Joseph
  full_name: Joseph O'Neill
  id: 426376DC-F248-11E8-B48F-1D18A9856A87
  last_name: O'Neill
- first_name: Barty
  full_name: Pleydell-Bouverie, Barty
  last_name: Pleydell Bouverie
- first_name: David
  full_name: Dupret, David
  last_name: Dupret
- first_name: Jozsef L
  full_name: Jozsef Csicsvari
  id: 3FA14672-F248-11E8-B48F-1D18A9856A87
  last_name: Csicsvari
  orcid: 0000-0002-5193-4036
citation:
  ama: 'O’Neill J, Pleydell Bouverie B, Dupret D, Csicsvari JL. Play it again: reactivation
    of waking experience and memory. <i>Trends in Neurosciences</i>. 2010;33(5):220-229.
    doi:<a href="https://doi.org/10.1016/j.tins.2010.01.006">10.1016/j.tins.2010.01.006</a>'
  apa: 'O’Neill, J., Pleydell Bouverie, B., Dupret, D., &#38; Csicsvari, J. L. (2010).
    Play it again: reactivation of waking experience and memory. <i>Trends in Neurosciences</i>.
    Elsevier. <a href="https://doi.org/10.1016/j.tins.2010.01.006">https://doi.org/10.1016/j.tins.2010.01.006</a>'
  chicago: 'O’Neill, Joseph, Barty Pleydell Bouverie, David Dupret, and Jozsef L Csicsvari.
    “Play It Again: Reactivation of Waking Experience and Memory.” <i>Trends in Neurosciences</i>.
    Elsevier, 2010. <a href="https://doi.org/10.1016/j.tins.2010.01.006">https://doi.org/10.1016/j.tins.2010.01.006</a>.'
  ieee: 'J. O’Neill, B. Pleydell Bouverie, D. Dupret, and J. L. Csicsvari, “Play it
    again: reactivation of waking experience and memory,” <i>Trends in Neurosciences</i>,
    vol. 33, no. 5. Elsevier, pp. 220–229, 2010.'
  ista: 'O’Neill J, Pleydell Bouverie B, Dupret D, Csicsvari JL. 2010. Play it again:
    reactivation of waking experience and memory. Trends in Neurosciences. 33(5),
    220–229.'
  mla: 'O’Neill, Joseph, et al. “Play It Again: Reactivation of Waking Experience
    and Memory.” <i>Trends in Neurosciences</i>, vol. 33, no. 5, Elsevier, 2010, pp.
    220–29, doi:<a href="https://doi.org/10.1016/j.tins.2010.01.006">10.1016/j.tins.2010.01.006</a>.'
  short: J. O’Neill, B. Pleydell Bouverie, D. Dupret, J.L. Csicsvari, Trends in Neurosciences
    33 (2010) 220–229.
date_created: 2018-12-11T12:03:21Z
date_published: 2010-05-01T00:00:00Z
date_updated: 2021-01-12T07:43:29Z
day: '01'
doi: 10.1016/j.tins.2010.01.006
extern: 1
intvolume: '        33'
issue: '5'
month: '05'
page: 220 - 229
publication: Trends in Neurosciences
publication_status: published
publisher: Elsevier
publist_id: '2945'
quality_controlled: 0
status: public
title: 'Play it again: reactivation of waking experience and memory'
type: journal_article
volume: 33
year: '2010'
...
---
_id: '3459'
author:
- first_name: Bernd
  full_name: Fakler, Bernd
  last_name: Fakler
- first_name: Peter M
  full_name: Peter Jonas
  id: 353C1B58-F248-11E8-B48F-1D18A9856A87
  last_name: Jonas
  orcid: 0000-0001-5001-4804
citation:
  ama: 'Fakler B, Jonas PM. Grundlagen zellulärer Erregbarkeit. In: Schmidt R, Heckmann
    M, Lang F, eds. <i>Physiologie Des Menschen</i>. Springer; 2010.'
  apa: Fakler, B., &#38; Jonas, P. M. (2010). Grundlagen zellulärer Erregbarkeit.
    In R. Schmidt, M. Heckmann, &#38; F. Lang (Eds.), <i>Physiologie Des Menschen</i>.
    Springer.
  chicago: Fakler, Bernd, and Peter M Jonas. “Grundlagen Zellulärer Erregbarkeit.”
    In <i>Physiologie Des Menschen</i>, edited by R. Schmidt, M. Heckmann, and Florian
    Lang. Springer, 2010.
  ieee: B. Fakler and P. M. Jonas, “Grundlagen zellulärer Erregbarkeit,” in <i>Physiologie
    Des Menschen</i>, R. Schmidt, M. Heckmann, and F. Lang, Eds. Springer, 2010.
  ista: 'Fakler B, Jonas PM. 2010.Grundlagen zellulärer Erregbarkeit. In: Physiologie
    Des Menschen. .'
  mla: Fakler, Bernd, and Peter M. Jonas. “Grundlagen Zellulärer Erregbarkeit.” <i>Physiologie
    Des Menschen</i>, edited by R. Schmidt et al., Springer, 2010.
  short: B. Fakler, P.M. Jonas, in:, R. Schmidt, M. Heckmann, F. Lang (Eds.), Physiologie
    Des Menschen, Springer, 2010.
date_created: 2018-12-11T12:03:26Z
date_published: 2010-01-01T00:00:00Z
date_updated: 2021-01-12T07:43:35Z
day: '01'
editor:
- first_name: R.
  full_name: Schmidt, R. F.
  last_name: Schmidt
- first_name: M.
  full_name: Heckmann, M.
  last_name: Heckmann
- first_name: Florian
  full_name: Lang, Florian
  last_name: Lang
extern: 1
month: '01'
publication: Physiologie Des Menschen
publication_status: published
publisher: Springer
publist_id: '2928'
quality_controlled: 0
status: public
title: Grundlagen zellulärer Erregbarkeit
type: book_chapter
year: '2010'
...
---
_id: '3498'
abstract:
- lang: eng
  text: "Purpose\r\nCalcifying tendinitis is a common condition of the shoulder. In
    many cases, arthroscopic reduction in the deposit is indicated. The localization
    of the deposit is sometimes challenging and time-consuming. Pre-operative ultrasound
    (US)-guided needle placement in the deposit and pre-operative US marking of the
    deposit at the skin with a ballpoint are described and recommended methods to
    alleviate the procedure without using ionizing radiation by fluoroscopy.\r\nMethods\r\nIntra-operative
    sonography of the shoulder is introduced as a new method to localize the calcific
    deposit with high accuracy. After standard arthroscopic buresectomy, the surgeon
    performs an ultrasound examination under sterile conditions to localize the deposits.
    A ventral longitudinal US section is recommended, and the upper arm is rotated
    until the deposit is visible. Subsequently, perpendicular to the skin at the position
    of the transducer, a needle is introduced under arthroscopic and ultrasound visualization
    to puncture the deposit.\r\nResults\r\nThe presence of snow-white crystals at
    the tip of the needle proves the exact localization. Consecutively, the curettage
    can be accomplished. Another intra-operative sonography evaluates possible calcific
    remnants and the tendon structure.\r\nConclusion\r\nThis new technique may alleviate
    arthroscopic calcific deposit curettage by visualizing the deposit without using
    ionizing radiation. Additionally, soft tissue damage due to decreased number of
    punctures to detect the deposit may be achieved. Both factors may contribute to
    reduced operation time."
author:
- first_name: M.
  full_name: Sabeti Aschraf, M.
  last_name: Sabeti Aschraf
- first_name: C.
  full_name: Gonano, C.
  last_name: Gonano
- first_name: E.
  full_name: Nemecek, E.
  last_name: Nemecek
- first_name: Lisa
  full_name: Cichocki, Lisa
  id: 3BC78B60-F248-11E8-B48F-1D18A9856A87
  last_name: Cichocki
- first_name: C.
  full_name: Schueller Weidekamm, C.
  last_name: Schueller Weidekamm
citation:
  ama: Sabeti Aschraf M, Gonano C, Nemecek E, Cichocki L, Schueller Weidekamm C. Intra-operative
    ultrasound facilitates the localization of the calcific deposit during arthroscopic
    treatment of calcifying tendinitis. <i>Knee Surgery, Sports Traumatology, Arthroscopy</i>.
    2010;18(12):1792-1794. doi:<a href="https://doi.org/10.1007/s00167-010-1227-9">10.1007/s00167-010-1227-9</a>
  apa: Sabeti Aschraf, M., Gonano, C., Nemecek, E., Cichocki, L., &#38; Schueller
    Weidekamm, C. (2010). Intra-operative ultrasound facilitates the localization
    of the calcific deposit during arthroscopic treatment of calcifying tendinitis.
    <i>Knee Surgery, Sports Traumatology, Arthroscopy</i>. Springer. <a href="https://doi.org/10.1007/s00167-010-1227-9">https://doi.org/10.1007/s00167-010-1227-9</a>
  chicago: Sabeti Aschraf, M., C. Gonano, E. Nemecek, Lisa Cichocki, and C. Schueller
    Weidekamm. “Intra-Operative Ultrasound Facilitates the Localization of the Calcific
    Deposit during Arthroscopic Treatment of Calcifying Tendinitis.” <i>Knee Surgery,
    Sports Traumatology, Arthroscopy</i>. Springer, 2010. <a href="https://doi.org/10.1007/s00167-010-1227-9">https://doi.org/10.1007/s00167-010-1227-9</a>.
  ieee: M. Sabeti Aschraf, C. Gonano, E. Nemecek, L. Cichocki, and C. Schueller Weidekamm,
    “Intra-operative ultrasound facilitates the localization of the calcific deposit
    during arthroscopic treatment of calcifying tendinitis,” <i>Knee Surgery, Sports
    Traumatology, Arthroscopy</i>, vol. 18, no. 12. Springer, pp. 1792–1794, 2010.
  ista: Sabeti Aschraf M, Gonano C, Nemecek E, Cichocki L, Schueller Weidekamm C.
    2010. Intra-operative ultrasound facilitates the localization of the calcific
    deposit during arthroscopic treatment of calcifying tendinitis. Knee Surgery,
    Sports Traumatology, Arthroscopy. 18(12), 1792–1794.
  mla: Sabeti Aschraf, M., et al. “Intra-Operative Ultrasound Facilitates the Localization
    of the Calcific Deposit during Arthroscopic Treatment of Calcifying Tendinitis.”
    <i>Knee Surgery, Sports Traumatology, Arthroscopy</i>, vol. 18, no. 12, Springer,
    2010, pp. 1792–94, doi:<a href="https://doi.org/10.1007/s00167-010-1227-9">10.1007/s00167-010-1227-9</a>.
  short: M. Sabeti Aschraf, C. Gonano, E. Nemecek, L. Cichocki, C. Schueller Weidekamm,
    Knee Surgery, Sports Traumatology, Arthroscopy 18 (2010) 1792–1794.
date_created: 2018-12-11T12:03:39Z
date_published: 2010-08-20T00:00:00Z
date_updated: 2021-01-12T07:43:51Z
day: '20'
doi: 10.1007/s00167-010-1227-9
intvolume: '        18'
issue: '12'
language:
- iso: eng
month: '08'
oa_version: None
page: 1792 - 1794
publication: Knee Surgery, Sports Traumatology, Arthroscopy
publication_status: published
publisher: Springer
publist_id: '2889'
quality_controlled: '1'
scopus_import: 1
status: public
title: Intra-operative ultrasound facilitates the localization of the calcific deposit
  during arthroscopic treatment of calcifying tendinitis
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 18
year: '2010'
...
---
_id: '3538'
abstract:
- lang: eng
  text: How seizures start is a major question in epilepsy research. Preictal EEG
    changes occur in both human patients and animal models, but their underlying mechanisms
    and relationship with seizure initiation remain unknown. Here we demonstrate the
    existence, in the hippocampal CA1 region, of a preictal state characterized by
    the progressive and global increase in neuronal activity associated with a widespread
    buildup of low-amplitude high-frequency activity (HFA) (&gt; 100 Hz) and reduction
    in system complexity. HFA is generated by the firing of neurons, mainly pyramidal
    cells, at much lower frequencies. Individual cycles of HFA are generated by the
    near-synchronous (within similar to 5 ms) firing of small numbers of pyramidal
    cells. The presence of HFA in the low-calcium model implicates nonsynaptic synchronization;
    the presence of very similar HFA in the high-potassium model shows that it does
    not depend on an absence of synaptic transmission. Immediately before seizure
    onset, CA1 is in a state of high sensitivity in which weak depolarizing or synchronizing
    perturbations can trigger seizures. Transition to seizure is characterized by
    a rapid expansion and fusion of the neuronal populations responsible for HFA,
    associated with a progressive slowing of HFA, leading to a single, massive, hypersynchronous
    cluster generating the high-amplitude low-frequency activity of the seizure.
author:
- first_name: Premysl
  full_name: Jiruska, Premysl
  last_name: Jiruska
- first_name: Jozsef L
  full_name: Csicsvari, Jozsef L
  id: 3FA14672-F248-11E8-B48F-1D18A9856A87
  last_name: Csicsvari
  orcid: 0000-0002-5193-4036
- first_name: Andrew
  full_name: Powell, Andrew
  last_name: Powell
- first_name: John
  full_name: Fox, John
  last_name: Fox
- first_name: Wei
  full_name: Chang, Wei
  last_name: Chang
- first_name: Martin
  full_name: Vreugdenhil, Martin
  last_name: Vreugdenhil
- first_name: Xiaoli
  full_name: Li, Xiaoli
  last_name: Li
- first_name: Milan
  full_name: Palus, Milan
  last_name: Palus
- first_name: Alejandro
  full_name: Bujan, Alejandro
  last_name: Bujan
- first_name: Richard
  full_name: Dearden, Richard
  last_name: Dearden
- first_name: John
  full_name: Jefferys, John
  last_name: Jefferys
citation:
  ama: Jiruska P, Csicsvari JL, Powell A, et al. High-frequency network activity,
    global increase in neuronal activity, and synchrony expansion precede epileptic
    seizures in vitro. <i>Journal of Neuroscience</i>. 2010;30(16):5690-5701. doi:<a
    href="https://doi.org/10.1523/JNEUROSCI.0535-10.2010">10.1523/JNEUROSCI.0535-10.2010</a>
  apa: Jiruska, P., Csicsvari, J. L., Powell, A., Fox, J., Chang, W., Vreugdenhil,
    M., … Jefferys, J. (2010). High-frequency network activity, global increase in
    neuronal activity, and synchrony expansion precede epileptic seizures in vitro.
    <i>Journal of Neuroscience</i>. Society for Neuroscience. <a href="https://doi.org/10.1523/JNEUROSCI.0535-10.2010">https://doi.org/10.1523/JNEUROSCI.0535-10.2010</a>
  chicago: Jiruska, Premysl, Jozsef L Csicsvari, Andrew Powell, John Fox, Wei Chang,
    Martin Vreugdenhil, Xiaoli Li, et al. “High-Frequency Network Activity, Global
    Increase in Neuronal Activity, and Synchrony Expansion Precede Epileptic Seizures
    in Vitro.” <i>Journal of Neuroscience</i>. Society for Neuroscience, 2010. <a
    href="https://doi.org/10.1523/JNEUROSCI.0535-10.2010">https://doi.org/10.1523/JNEUROSCI.0535-10.2010</a>.
  ieee: P. Jiruska <i>et al.</i>, “High-frequency network activity, global increase
    in neuronal activity, and synchrony expansion precede epileptic seizures in vitro,”
    <i>Journal of Neuroscience</i>, vol. 30, no. 16. Society for Neuroscience, pp.
    5690–5701, 2010.
  ista: Jiruska P, Csicsvari JL, Powell A, Fox J, Chang W, Vreugdenhil M, Li X, Palus
    M, Bujan A, Dearden R, Jefferys J. 2010. High-frequency network activity, global
    increase in neuronal activity, and synchrony expansion precede epileptic seizures
    in vitro. Journal of Neuroscience. 30(16), 5690–5701.
  mla: Jiruska, Premysl, et al. “High-Frequency Network Activity, Global Increase
    in Neuronal Activity, and Synchrony Expansion Precede Epileptic Seizures in Vitro.”
    <i>Journal of Neuroscience</i>, vol. 30, no. 16, Society for Neuroscience, 2010,
    pp. 5690–701, doi:<a href="https://doi.org/10.1523/JNEUROSCI.0535-10.2010">10.1523/JNEUROSCI.0535-10.2010</a>.
  short: P. Jiruska, J.L. Csicsvari, A. Powell, J. Fox, W. Chang, M. Vreugdenhil,
    X. Li, M. Palus, A. Bujan, R. Dearden, J. Jefferys, Journal of Neuroscience 30
    (2010) 5690–5701.
date_created: 2018-12-11T12:03:51Z
date_published: 2010-04-21T00:00:00Z
date_updated: 2021-01-12T07:44:10Z
day: '21'
doi: 10.1523/JNEUROSCI.0535-10.2010
extern: '1'
intvolume: '        30'
issue: '16'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://www.jneurosci.org/content/30/16/5690
month: '04'
oa: 1
oa_version: None
page: 5690 - 5701
publication: Journal of Neuroscience
publication_status: published
publisher: Society for Neuroscience
publist_id: '2848'
quality_controlled: '1'
status: public
title: High-frequency network activity, global increase in neuronal activity, and
  synchrony expansion precede epileptic seizures in vitro
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 30
year: '2010'
...
---
_id: '3592'
abstract:
- lang: eng
  text: The zebrafish is a favorite model organism to study tissue morphogenesis during
    development at a subcellular level. This largely results from the fact that zebrafish
    embryos are transparent and thus accessible to various imaging techniques, such
    as confocal and two-photon excitation (2PE) microscopy. In particular, 2PE microscopy
    has been shown to be useful for imaging deep cell layers within the embryo and
    following tissue morphogenesis over long periods. This chapter describes how to
    use 2PE microscopy to study morphogenetic movements during early zebrafish embryonic
    development, providing a general blueprint for its use in zebrafish.
article_processing_charge: No
author:
- first_name: Lara
  full_name: Carvalho, Lara
  last_name: Carvalho
- first_name: Carl-Philipp J
  full_name: Heisenberg, Carl-Philipp J
  id: 39427864-F248-11E8-B48F-1D18A9856A87
  last_name: Heisenberg
  orcid: 0000-0002-0912-4566
citation:
  ama: Carvalho L, Heisenberg C-PJ. Imaging zebrafish embryos by two-photon excitation
    time-lapse microscopy. <i>Methods in Molecular Biology</i>. 2010;546(Part 5):273-287.
    doi:<a href="https://doi.org/10.1007/978-1-60327-977-2_17">10.1007/978-1-60327-977-2_17</a>
  apa: Carvalho, L., &#38; Heisenberg, C.-P. J. (2010). Imaging zebrafish embryos
    by two-photon excitation time-lapse microscopy. <i>Methods in Molecular Biology</i>.
    Springer. <a href="https://doi.org/10.1007/978-1-60327-977-2_17">https://doi.org/10.1007/978-1-60327-977-2_17</a>
  chicago: Carvalho, Lara, and Carl-Philipp J Heisenberg. “Imaging Zebrafish Embryos
    by Two-Photon Excitation Time-Lapse Microscopy.” <i>Methods in Molecular Biology</i>.
    Springer, 2010. <a href="https://doi.org/10.1007/978-1-60327-977-2_17">https://doi.org/10.1007/978-1-60327-977-2_17</a>.
  ieee: L. Carvalho and C.-P. J. Heisenberg, “Imaging zebrafish embryos by two-photon
    excitation time-lapse microscopy,” <i>Methods in Molecular Biology</i>, vol. 546,
    no. Part 5. Springer, pp. 273–287, 2010.
  ista: Carvalho L, Heisenberg C-PJ. 2010. Imaging zebrafish embryos by two-photon
    excitation time-lapse microscopy. Methods in Molecular Biology. 546(Part 5), 273–287.
  mla: Carvalho, Lara, and Carl-Philipp J. Heisenberg. “Imaging Zebrafish Embryos
    by Two-Photon Excitation Time-Lapse Microscopy.” <i>Methods in Molecular Biology</i>,
    vol. 546, no. Part 5, Springer, 2010, pp. 273–87, doi:<a href="https://doi.org/10.1007/978-1-60327-977-2_17">10.1007/978-1-60327-977-2_17</a>.
  short: L. Carvalho, C.-P.J. Heisenberg, Methods in Molecular Biology 546 (2010)
    273–287.
date_created: 2018-12-11T12:04:08Z
date_published: 2010-01-01T00:00:00Z
date_updated: 2021-01-12T07:44:31Z
day: '01'
doi: 10.1007/978-1-60327-977-2_17
extern: '1'
intvolume: '       546'
issue: Part 5
language:
- iso: eng
month: '01'
oa_version: None
page: 273 - 287
publication: Methods in Molecular Biology
publication_status: published
publisher: Springer
publist_id: '2791'
status: public
title: Imaging zebrafish embryos by two-photon excitation time-lapse microscopy
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 546
year: '2010'
...
