---
_id: '8507'
abstract:
- lang: eng
text: "We study a Cr nearly integrable Hamiltonian system defined on \U0001D54B3
× ℝ3. Let and µΣ1 be the restriction of Lebesgue measure on \U0001D54B3 × ℝ3
to ∑. We prove there is a perturbation , and an orbit (q(t), p(t)): ℝ → \U0001D54B3
× ℝ3 of the Hamiltonian equation such that ."
article_processing_charge: No
author:
- first_name: Vadim
full_name: Kaloshin, Vadim
id: FE553552-CDE8-11E9-B324-C0EBE5697425
last_name: Kaloshin
orcid: 0000-0002-6051-2628
- first_name: KE
full_name: ZHANG, KE
last_name: ZHANG
- first_name: YONG
full_name: ZHENG, YONG
last_name: ZHENG
citation:
ama: 'Kaloshin V, ZHANG K, ZHENG Y. Almost dense orbit on energy surface. In: XVIth
International Congress on Mathematical Physics. World Scientific; 2010:314-322.
doi:10.1142/9789814304634_0017'
apa: 'Kaloshin, V., ZHANG, K., & ZHENG, Y. (2010). Almost dense orbit on energy
surface. In XVIth International Congress on Mathematical Physics (pp. 314–322).
Prague, Czech Republic: World Scientific. https://doi.org/10.1142/9789814304634_0017'
chicago: Kaloshin, Vadim, KE ZHANG, and YONG ZHENG. “Almost Dense Orbit on Energy
Surface.” In XVIth International Congress on Mathematical Physics, 314–22.
World Scientific, 2010. https://doi.org/10.1142/9789814304634_0017.
ieee: V. Kaloshin, K. ZHANG, and Y. ZHENG, “Almost dense orbit on energy surface,”
in XVIth International Congress on Mathematical Physics, Prague, Czech
Republic, 2010, pp. 314–322.
ista: Kaloshin V, ZHANG K, ZHENG Y. 2010. Almost dense orbit on energy surface.
XVIth International Congress on Mathematical Physics. International Congress on
Mathematical Physics, 314–322.
mla: Kaloshin, Vadim, et al. “Almost Dense Orbit on Energy Surface.” XVIth International
Congress on Mathematical Physics, World Scientific, 2010, pp. 314–22, doi:10.1142/9789814304634_0017.
short: V. Kaloshin, K. ZHANG, Y. ZHENG, in:, XVIth International Congress on Mathematical
Physics, World Scientific, 2010, pp. 314–322.
conference:
end_date: 2009-08-08
location: Prague, Czech Republic
name: International Congress on Mathematical Physics
start_date: 2009-08-03
date_created: 2020-09-18T10:47:56Z
date_published: 2010-03-01T00:00:00Z
date_updated: 2021-01-12T08:19:46Z
day: '01'
doi: 10.1142/9789814304634_0017
extern: '1'
language:
- iso: eng
month: '03'
oa_version: None
page: 314-322
publication: XVIth International Congress on Mathematical Physics
publication_identifier:
isbn:
- '9789814304627'
- '9789814304634'
publication_status: published
publisher: World Scientific
quality_controlled: '1'
status: public
title: Almost dense orbit on energy surface
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2010'
...
---
_id: '857'
abstract:
- lang: eng
text: 'The need to maintain the structural and functional integrity of an evolving
protein severely restricts the repertoire of acceptable amino-acid substitutions.
However, it is not known whether these restrictions impose a global limit on how
far homologous protein sequences can diverge from each other. Here we explore
the limits of protein evolution using sequence divergence data. We formulate a
computational approach to study the rate of divergence of distant protein sequences
and measure this rate for ancient proteins, those that were present in the last
universal common ancestor. We show that ancient proteins are still diverging from
each other, indicating an ongoing expansion of the protein sequence universe.
The slow rate of this divergence is imposed by the sparseness of functional protein
sequences in sequence space and the ruggedness of the protein fitness landscape:
98 per cent of sites cannot accept an amino-acid substitution at any given moment
but a vast majority of all sites may eventually be permitted to evolve when other,
compensatory, changes occur. Thus, 3.5 × 10 9 yr has not been enough to reach
the limit of divergent evolution of proteins, and for most proteins the limit
of sequence similarity imposed by common function may not exceed that of random
sequences.'
acknowledgement: |
We thank E. Koonin, Y. Wolf, A. Lobkovsky, D. Petrov, D. Ivankov, J. Sharpe, B. Lehner, Y. Jaeger, P. Vlasov, M. Ptitsyn and M. Roytberg for discussions and A. Kondrashov for extensive feedback on our manuscript. We thank D. Tawfik for inspiring us to start the investigation of the functional limits in sequence space.
author:
- first_name: Inna
full_name: Povolotskaya, Inna
last_name: Povolotskaya
- first_name: Fyodor
full_name: Fyodor Kondrashov
id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
last_name: Kondrashov
orcid: 0000-0001-8243-4694
citation:
ama: Povolotskaya I, Kondrashov F. Sequence space and the ongoing expansion of the
protein universe. Nature. 2010;465(7300):922-926. doi:10.1038/nature09105
apa: Povolotskaya, I., & Kondrashov, F. (2010). Sequence space and the ongoing
expansion of the protein universe. Nature. Nature Publishing Group. https://doi.org/10.1038/nature09105
chicago: Povolotskaya, Inna, and Fyodor Kondrashov. “Sequence Space and the Ongoing
Expansion of the Protein Universe.” Nature. Nature Publishing Group, 2010.
https://doi.org/10.1038/nature09105.
ieee: I. Povolotskaya and F. Kondrashov, “Sequence space and the ongoing expansion
of the protein universe,” Nature, vol. 465, no. 7300. Nature Publishing
Group, pp. 922–926, 2010.
ista: Povolotskaya I, Kondrashov F. 2010. Sequence space and the ongoing expansion
of the protein universe. Nature. 465(7300), 922–926.
mla: Povolotskaya, Inna, and Fyodor Kondrashov. “Sequence Space and the Ongoing
Expansion of the Protein Universe.” Nature, vol. 465, no. 7300, Nature
Publishing Group, 2010, pp. 922–26, doi:10.1038/nature09105.
short: I. Povolotskaya, F. Kondrashov, Nature 465 (2010) 922–926.
date_created: 2018-12-11T11:48:52Z
date_published: 2010-06-17T00:00:00Z
date_updated: 2021-01-12T08:20:05Z
day: '17'
doi: 10.1038/nature09105
extern: 1
intvolume: ' 465'
issue: '7300'
month: '06'
page: 922 - 926
publication: Nature
publication_status: published
publisher: Nature Publishing Group
publist_id: '6791'
quality_controlled: 0
status: public
title: Sequence space and the ongoing expansion of the protein universe
type: journal_article
volume: 465
year: '2010'
...
---
_id: '862'
abstract:
- lang: eng
text: A long-standing controversy in evolutionary biology is whether or not evolving
lineages can cross valleys on the fitness landscape that correspond to low-fitness
genotypes, which can eventually enable them to reach isolated fitness peaks1-9.
Here we study the fitness landscapes traversed by switches between different AU
and GC Watson-Crick nucleotide pairs at complementary sites of mitochondrial transfer
RNA stem regions in 83 mammalian species. We find that such Watson-Crick switches
occur 30-40 times more slowly than pairs of neutral substitutions, and that alleles
corresponding to GU and AC non-Watson-Crick intermediate states segregate within
human populations at low frequencies, similar to those of non-synonymous alleles.
Substitutions leading to a Watson-Crick switch are strongly correlated, especially
in mitochondrial tRNAs encoded on the GT-nucleotide-rich strand of the mitochondrial
genome. Using these data we estimate that a typical Watson-Crick switch involves
crossing a fitness valley of a depth of about 10-3 or even about 10-2, with AC
intermediates being slightly more deleterious than GU intermediates. This compensatory
evolution must proceed through rare intermediate variants that never reach fixation.
The ubiquitous nature of compensatory evolution in mammalian mitochondrial tRNAs
and other molecules implies that simultaneous fixation of two alleles that are
individually deleterious may be a common phenomenon at the molecular level.
acknowledgement: We thank H. Innan, M. Laessig, R. Guigo, I. Povolotskaya, D. Ivankov
and M. Breen for thoughtful discussions and critical reading of the manuscript.
author:
- first_name: Margarita
full_name: Meer, Margarita V
last_name: Meer
- first_name: Alexey
full_name: Kondrashov, Alexey S
last_name: Kondrashov
- first_name: Yael
full_name: Artzy-Randrup, Yael
last_name: Artzy Randrup
- first_name: Fyodor
full_name: Fyodor Kondrashov
id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
last_name: Kondrashov
orcid: 0000-0001-8243-4694
citation:
ama: Meer M, Kondrashov A, Artzy Randrup Y, Kondrashov F. Compensatory evolution
in mitochondrial tRNAs navigates valleys of low fitness. Nature. 2010;464(7286):279-282.
doi:10.1038/nature08691
apa: Meer, M., Kondrashov, A., Artzy Randrup, Y., & Kondrashov, F. (2010). Compensatory
evolution in mitochondrial tRNAs navigates valleys of low fitness. Nature.
Nature Publishing Group. https://doi.org/10.1038/nature08691
chicago: Meer, Margarita, Alexey Kondrashov, Yael Artzy Randrup, and Fyodor Kondrashov.
“Compensatory Evolution in Mitochondrial TRNAs Navigates Valleys of Low Fitness.”
Nature. Nature Publishing Group, 2010. https://doi.org/10.1038/nature08691.
ieee: M. Meer, A. Kondrashov, Y. Artzy Randrup, and F. Kondrashov, “Compensatory
evolution in mitochondrial tRNAs navigates valleys of low fitness,” Nature,
vol. 464, no. 7286. Nature Publishing Group, pp. 279–282, 2010.
ista: Meer M, Kondrashov A, Artzy Randrup Y, Kondrashov F. 2010. Compensatory evolution
in mitochondrial tRNAs navigates valleys of low fitness. Nature. 464(7286), 279–282.
mla: Meer, Margarita, et al. “Compensatory Evolution in Mitochondrial TRNAs Navigates
Valleys of Low Fitness.” Nature, vol. 464, no. 7286, Nature Publishing
Group, 2010, pp. 279–82, doi:10.1038/nature08691.
short: M. Meer, A. Kondrashov, Y. Artzy Randrup, F. Kondrashov, Nature 464 (2010)
279–282.
date_created: 2018-12-11T11:48:54Z
date_published: 2010-03-11T00:00:00Z
date_updated: 2021-01-12T08:20:20Z
day: '11'
doi: 10.1038/nature08691
extern: 1
intvolume: ' 464'
issue: '7286'
month: '03'
page: 279 - 282
publication: Nature
publication_status: published
publisher: Nature Publishing Group
publist_id: '6784'
quality_controlled: 0
status: public
title: Compensatory evolution in mitochondrial tRNAs navigates valleys of low fitness
type: journal_article
volume: 464
year: '2010'
...
---
_id: '872'
abstract:
- lang: eng
text: The rate of spontaneous mutation in natural populations is a fundamental parameter
for many evolutionary phenomena. Because the rate of mutation is generally low,
most of what is currently known about mutation has been obtained through indirect,
complex and imprecise methodological approaches. However, in the past few years
genome-wide sequencing of closely related individuals has made it possible to
estimate the rates of mutation directly at the level of the DNA, avoiding most
of the problems associated with using indirect methods. Here, we review the methods
used in the past with an emphasis on next generation sequencing, which may soon
make the accurate measurement of spontaneous mutation rates a matter of routine.
author:
- first_name: Fyodor
full_name: Fyodor Kondrashov
id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
last_name: Kondrashov
orcid: 0000-0001-8243-4694
- first_name: Alexey
full_name: Kondrashov, Alexey S
last_name: Kondrashov
citation:
ama: Kondrashov F, Kondrashov A. Measurements of spontaneous rates of mutations
in the recent past and the near future. Philosophical Transactions of the Royal
Society of London Series B, Biological Sciences. 2010;365(1544):1169-1176.
doi:10.1098/rstb.2009.0286
apa: Kondrashov, F., & Kondrashov, A. (2010). Measurements of spontaneous rates
of mutations in the recent past and the near future. Philosophical Transactions
of the Royal Society of London. Series B, Biological Sciences. Royal Society,
The. https://doi.org/10.1098/rstb.2009.0286
chicago: Kondrashov, Fyodor, and Alexey Kondrashov. “Measurements of Spontaneous
Rates of Mutations in the Recent Past and the near Future.” Philosophical Transactions
of the Royal Society of London. Series B, Biological Sciences. Royal Society,
The, 2010. https://doi.org/10.1098/rstb.2009.0286.
ieee: F. Kondrashov and A. Kondrashov, “Measurements of spontaneous rates of mutations
in the recent past and the near future,” Philosophical Transactions of the
Royal Society of London. Series B, Biological Sciences, vol. 365, no. 1544.
Royal Society, The, pp. 1169–1176, 2010.
ista: Kondrashov F, Kondrashov A. 2010. Measurements of spontaneous rates of mutations
in the recent past and the near future. Philosophical Transactions of the Royal
Society of London. Series B, Biological Sciences. 365(1544), 1169–1176.
mla: Kondrashov, Fyodor, and Alexey Kondrashov. “Measurements of Spontaneous Rates
of Mutations in the Recent Past and the near Future.” Philosophical Transactions
of the Royal Society of London. Series B, Biological Sciences, vol. 365, no.
1544, Royal Society, The, 2010, pp. 1169–76, doi:10.1098/rstb.2009.0286.
short: F. Kondrashov, A. Kondrashov, Philosophical Transactions of the Royal Society
of London. Series B, Biological Sciences 365 (2010) 1169–1176.
date_created: 2018-12-11T11:48:57Z
date_published: 2010-04-27T00:00:00Z
date_updated: 2021-01-12T08:20:43Z
day: '27'
doi: 10.1098/rstb.2009.0286
extern: 1
intvolume: ' 365'
issue: '1544'
month: '04'
page: 1169 - 1176
publication: Philosophical Transactions of the Royal Society of London. Series B,
Biological Sciences
publication_status: published
publisher: Royal Society, The
publist_id: '6772'
quality_controlled: 0
status: public
title: Measurements of spontaneous rates of mutations in the recent past and the near
future
type: journal_article
volume: 365
year: '2010'
...
---
_id: '884'
abstract:
- lang: eng
text: 'Background: Divergence of two independently evolving sequences that originated
from a common ancestor can be described by two parameters, the asymptotic level
of divergence E and the rate r at which this level of divergence is approached.
Constant negative selection impedes allele replacements and, therefore, is routinely
assumed to decelerate sequence divergence. However, its impact on E and on r has
not been formally investigated.Results: Strong selection that favors only one
allele can make E arbitrarily small and r arbitrarily large. In contrast, in the
case of 4 possible alleles and equal mutation rates, the lowest value of r, attained
when two alleles confer equal fitnesses and the other two are strongly deleterious,
is only two times lower than its value under selective neutrality.Conclusions:
Constant selection can strongly constrain the level of sequence divergence, but
cannot reduce substantially the rate at which this level is approached. In particular,
under any constant selection the divergence of sequences that accumulated one
substitution per neutral site since their origin from the common ancestor must
already constitute at least one half of the asymptotic divergence at sites under
such selection.Reviewers: This article was reviewed by Drs. Nicolas Galtier, Sergei
Maslov, and Nick Grishin.'
author:
- first_name: Alexey
full_name: Kondrashov, Alexey S
last_name: Kondrashov
- first_name: Inna
full_name: Povolotskaya, Inna
last_name: Povolotskaya
- first_name: Dmitry
full_name: Ivankov, Dmitry N
last_name: Ivankov
- first_name: Fyodor
full_name: Fyodor Kondrashov
id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
last_name: Kondrashov
orcid: 0000-0001-8243-4694
citation:
ama: Kondrashov A, Povolotskaya I, Ivankov D, Kondrashov F. Rate of sequence divergence
under constant selection. Biology Direct. 2010;5. doi:10.1186/1745-6150-5-5
apa: Kondrashov, A., Povolotskaya, I., Ivankov, D., & Kondrashov, F. (2010).
Rate of sequence divergence under constant selection. Biology Direct. BioMed
Central. https://doi.org/10.1186/1745-6150-5-5
chicago: Kondrashov, Alexey, Inna Povolotskaya, Dmitry Ivankov, and Fyodor Kondrashov.
“Rate of Sequence Divergence under Constant Selection.” Biology Direct.
BioMed Central, 2010. https://doi.org/10.1186/1745-6150-5-5.
ieee: A. Kondrashov, I. Povolotskaya, D. Ivankov, and F. Kondrashov, “Rate of sequence
divergence under constant selection,” Biology Direct, vol. 5. BioMed Central,
2010.
ista: Kondrashov A, Povolotskaya I, Ivankov D, Kondrashov F. 2010. Rate of sequence
divergence under constant selection. Biology Direct. 5.
mla: Kondrashov, Alexey, et al. “Rate of Sequence Divergence under Constant Selection.”
Biology Direct, vol. 5, BioMed Central, 2010, doi:10.1186/1745-6150-5-5.
short: A. Kondrashov, I. Povolotskaya, D. Ivankov, F. Kondrashov, Biology Direct
5 (2010).
date_created: 2018-12-11T11:49:00Z
date_published: 2010-01-21T00:00:00Z
date_updated: 2021-01-12T08:21:15Z
day: '21'
doi: 10.1186/1745-6150-5-5
extern: 1
intvolume: ' 5'
month: '01'
publication: Biology Direct
publication_status: published
publisher: BioMed Central
publist_id: '6762'
quality_controlled: 0
status: public
title: Rate of sequence divergence under constant selection
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
volume: 5
year: '2010'
...
---
_id: '89'
abstract:
- lang: eng
text: We demonstrate the operation of a device that can produce chitosan nanoparticles
in a tunable size range from 50-300 nm with small size dispersion. A piezoelectric
oscillator operated at megahertz frequencies is used to aerosolize a solution
containing dissolved chitosan. The solvent is then evaporated from the aerosolized
droplets in a heat pipe, leaving monodisperse nanoparticles to be collected. The
nanoparticle size is controlled both by the concentration of the dissolved polymer
and by the size of the aerosol droplets that are created. Our device can be used
with any polymer or polymer/therapeutic combination that can be prepared in a
homogeneous solution and vaporized.
acknowledgement: This work was supported by the National Science Foundation under
Grants PHY-0456898 and PHY-0757989, and acknowledgment is made to the Donors of
the Petroleum Research Fund administered by the American Chemical Society for partial
support of this research.
author:
- first_name: Ian
full_name: Wright, Ian
last_name: Wright
- first_name: Andrew P
full_name: Higginbotham, Andrew P
id: 4AD6785A-F248-11E8-B48F-1D18A9856A87
last_name: Higginbotham
orcid: 0000-0003-2607-2363
- first_name: Shenda
full_name: Baker, Shenda
last_name: Baker
- first_name: Tom
full_name: Donnelly, Tom
last_name: Donnelly
citation:
ama: Wright I, Higginbotham AP, Baker S, Donnelly T. Generation of nanoparticles
of controlled size using ultrasonic piezoelectric oscillators in solution. ACS
Applied Materials and Interfaces. 2010;2(8):2360-2364. doi:10.1021/am100375w
apa: Wright, I., Higginbotham, A. P., Baker, S., & Donnelly, T. (2010). Generation
of nanoparticles of controlled size using ultrasonic piezoelectric oscillators
in solution. ACS Applied Materials and Interfaces. American Chemical Society.
https://doi.org/10.1021/am100375w
chicago: Wright, Ian, Andrew P Higginbotham, Shenda Baker, and Tom Donnelly. “Generation
of Nanoparticles of Controlled Size Using Ultrasonic Piezoelectric Oscillators
in Solution.” ACS Applied Materials and Interfaces. American Chemical Society,
2010. https://doi.org/10.1021/am100375w.
ieee: I. Wright, A. P. Higginbotham, S. Baker, and T. Donnelly, “Generation of nanoparticles
of controlled size using ultrasonic piezoelectric oscillators in solution,” ACS
Applied Materials and Interfaces, vol. 2, no. 8. American Chemical Society,
pp. 2360–2364, 2010.
ista: Wright I, Higginbotham AP, Baker S, Donnelly T. 2010. Generation of nanoparticles
of controlled size using ultrasonic piezoelectric oscillators in solution. ACS
Applied Materials and Interfaces. 2(8), 2360–2364.
mla: Wright, Ian, et al. “Generation of Nanoparticles of Controlled Size Using Ultrasonic
Piezoelectric Oscillators in Solution.” ACS Applied Materials and Interfaces,
vol. 2, no. 8, American Chemical Society, 2010, pp. 2360–64, doi:10.1021/am100375w.
short: I. Wright, A.P. Higginbotham, S. Baker, T. Donnelly, ACS Applied Materials
and Interfaces 2 (2010) 2360–2364.
date_created: 2018-12-11T11:44:34Z
date_published: 2010-07-20T00:00:00Z
date_updated: 2021-01-12T08:21:17Z
day: '20'
doi: 10.1021/am100375w
extern: '1'
external_id:
pmid:
- ' 20735108'
intvolume: ' 2'
issue: '8'
language:
- iso: eng
month: '07'
oa_version: None
page: 2360 - 2364
pmid: 1
publication: ACS Applied Materials and Interfaces
publication_status: published
publisher: American Chemical Society
publist_id: '7965'
quality_controlled: '1'
status: public
title: Generation of nanoparticles of controlled size using ultrasonic piezoelectric
oscillators in solution
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 2
year: '2010'
...
---
_id: '891'
abstract:
- lang: eng
text: Gene duplications and their subsequent divergence play an important part in
the evolution of novel gene functions. Several models for the emergence, maintenance
and evolution of gene copies have been proposed. However, a clear consensus on
how gene duplications are fixed and maintained in genomes is lacking. Here, we
present a comprehensive classification of the models that are relevant to all
stages of the evolution of gene duplications. Each model predicts a unique combination
of evolutionary dynamics and functional properties. Setting out these predictions
is an important step towards identifying the main mechanisms that are involved
in the evolution of gene duplications.
acknowledgement: |
We thank M. Lynch for insightful comments on the manuscript.
author:
- first_name: Hideki
full_name: Innan, Hideki
last_name: Innan
- first_name: Fyodor
full_name: Fyodor Kondrashov
id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
last_name: Kondrashov
orcid: 0000-0001-8243-4694
citation:
ama: 'Innan H, Kondrashov F. The evolution of gene duplications: Classifying and
distinguishing between models. Nature Reviews Genetics. 2010;11(2):97-108.
doi:10.1038/nrg2689'
apa: 'Innan, H., & Kondrashov, F. (2010). The evolution of gene duplications:
Classifying and distinguishing between models. Nature Reviews Genetics.
Nature Publishing Group. https://doi.org/10.1038/nrg2689'
chicago: 'Innan, Hideki, and Fyodor Kondrashov. “The Evolution of Gene Duplications:
Classifying and Distinguishing between Models.” Nature Reviews Genetics.
Nature Publishing Group, 2010. https://doi.org/10.1038/nrg2689.'
ieee: 'H. Innan and F. Kondrashov, “The evolution of gene duplications: Classifying
and distinguishing between models,” Nature Reviews Genetics, vol. 11, no.
2. Nature Publishing Group, pp. 97–108, 2010.'
ista: 'Innan H, Kondrashov F. 2010. The evolution of gene duplications: Classifying
and distinguishing between models. Nature Reviews Genetics. 11(2), 97–108.'
mla: 'Innan, Hideki, and Fyodor Kondrashov. “The Evolution of Gene Duplications:
Classifying and Distinguishing between Models.” Nature Reviews Genetics,
vol. 11, no. 2, Nature Publishing Group, 2010, pp. 97–108, doi:10.1038/nrg2689.'
short: H. Innan, F. Kondrashov, Nature Reviews Genetics 11 (2010) 97–108.
date_created: 2018-12-11T11:49:03Z
date_published: 2010-02-01T00:00:00Z
date_updated: 2021-01-12T08:21:19Z
day: '01'
doi: 10.1038/nrg2689
extern: 1
intvolume: ' 11'
issue: '2'
month: '02'
page: 97 - 108
publication: Nature Reviews Genetics
publication_status: published
publisher: Nature Publishing Group
publist_id: '6755'
quality_controlled: 0
status: public
title: 'The evolution of gene duplications: Classifying and distinguishing between
models'
type: journal_article
volume: 11
year: '2010'
...
---
_id: '1721'
acknowledgement: AK is funded by a Marie Curie fellowship. JB is funded by the MRC
(UK). The funders had no role in study design, data collection and analysis, decision
to publish, or preparation of the manuscript
author:
- first_name: Anna
full_name: Anna Kicheva
id: 3959A2A0-F248-11E8-B48F-1D18A9856A87
last_name: Kicheva
orcid: 0000-0003-4509-4998
- first_name: James
full_name: Briscoe, James
last_name: Briscoe
citation:
ama: Kicheva A, Briscoe J. Limbs made to measure. PLoS Biology. 2010;8(7).
doi:10.1371/journal.pbio.1000421
apa: Kicheva, A., & Briscoe, J. (2010). Limbs made to measure. PLoS Biology.
Public Library of Science. https://doi.org/10.1371/journal.pbio.1000421
chicago: Kicheva, Anna, and James Briscoe. “Limbs Made to Measure.” PLoS Biology.
Public Library of Science, 2010. https://doi.org/10.1371/journal.pbio.1000421.
ieee: A. Kicheva and J. Briscoe, “Limbs made to measure,” PLoS Biology, vol.
8, no. 7. Public Library of Science, 2010.
ista: Kicheva A, Briscoe J. 2010. Limbs made to measure. PLoS Biology. 8(7).
mla: Kicheva, Anna, and James Briscoe. “Limbs Made to Measure.” PLoS Biology,
vol. 8, no. 7, Public Library of Science, 2010, doi:10.1371/journal.pbio.1000421.
short: A. Kicheva, J. Briscoe, PLoS Biology 8 (2010).
date_created: 2018-12-11T11:53:39Z
date_published: 2010-07-01T00:00:00Z
date_updated: 2021-01-12T06:52:45Z
day: '01'
doi: 10.1371/journal.pbio.1000421
extern: 1
intvolume: ' 8'
issue: '7'
month: '07'
publication: PLoS Biology
publication_status: published
publisher: Public Library of Science
publist_id: '5407'
quality_controlled: 0
status: public
title: Limbs made to measure
type: journal_article
volume: 8
year: '2010'
...
---
_id: '1722'
abstract:
- lang: eng
text: Morphogens are secreted signalling molecules that act in a graded manner to
control the pattern of cellular differentiation in developing tissues. An example
is Sonic hedgehog (Shh), which acts in several developing vertebrate tissues,
including the central nervous system, to provide positional information during
embryonic patterning. Here we address how Shh signalling assigns the positional
identities of distinct neuronal subtype progenitors throughout the ventral neural
tube. Assays of intracellular signal transduction and gene expression indicate
that the duration as well as level of signalling is critical for morphogen interpretation.
Progenitors of the ventral neuronal subtypes are established sequentially, with
progressively more ventral identities requiring correspondingly higher levels
and longer periods of Shh signalling. Moreover, cells remain sensitive to changes
in Shh signalling for an extended time, reverting to antecedent identities if
signalling levels fall below a threshold. Thus, the duration of signalling is
important not only for the assignment but also for the refinement and maintenance
of positional identity. Together the data suggest a dynamic model for ventral
neural tube patterning in which positional information corresponds to the time
integral of Shh signalling. This suggests an alternative to conventional models
of morphogen action that rely solely on the level of signalling.
acknowledgement: 'NS was supported by a Marie Curie Fellowship (PIIF-GA-2008-219939)
and the Mochida Memorial Foundation for Medical and Pharmaceutical Research. Support
for VR was provided by an EMBO LTF, for AK by a FEBS LTF. ED was supported by the
Wellcome Trust (#080630). Work in the lab of JB is supported by the Medical Research
Council (UK). AP is a CNRS (Centre National de la Recherche Scientifique) Investigator.
This work was supported by grants from the Ministère de la Recherche (ACI Grant
#0220575) and the Association pour la Recherche sur le Cancer (Grant #4679) to AP.
BGN was supported by grants from the Whitehall Foundation (2004-05-90-APL), the
March of Dimes Foundation (5-FY2006-281), the Muscular Dystrophy Association (92901),
and the NINDS (NS053976)'
author:
- first_name: Éric
full_name: Dessaud, Éric
last_name: Dessaud
- first_name: Vanessa
full_name: Ribes, Vanessa
last_name: Ribes
- first_name: Nikolaos
full_name: Balaskas, Nikolaos
last_name: Balaskas
- first_name: Linlin
full_name: Yang, Linlin
last_name: Yang
- first_name: Alessandra
full_name: Pierani, Alessandra
last_name: Pierani
- first_name: Anna
full_name: Anna Kicheva
id: 3959A2A0-F248-11E8-B48F-1D18A9856A87
last_name: Kicheva
orcid: 0000-0003-4509-4998
- first_name: Bennett
full_name: Novitch, Bennett
last_name: Novitch
- first_name: James
full_name: Briscoe, James
last_name: Briscoe
- first_name: Noriaki
full_name: Sasai, Noriaki
last_name: Sasai
citation:
ama: Dessaud É, Ribes V, Balaskas N, et al. Dynamic assignment and maintenance of
positional identity in the ventral neural tube by the morphogen sonic hedgehog.
PLoS Biology. 2010;8(6). doi:10.1371/journal.pbio.1000382
apa: Dessaud, É., Ribes, V., Balaskas, N., Yang, L., Pierani, A., Kicheva, A., …
Sasai, N. (2010). Dynamic assignment and maintenance of positional identity in
the ventral neural tube by the morphogen sonic hedgehog. PLoS Biology.
Public Library of Science. https://doi.org/10.1371/journal.pbio.1000382
chicago: Dessaud, Éric, Vanessa Ribes, Nikolaos Balaskas, Linlin Yang, Alessandra
Pierani, Anna Kicheva, Bennett Novitch, James Briscoe, and Noriaki Sasai. “Dynamic
Assignment and Maintenance of Positional Identity in the Ventral Neural Tube by
the Morphogen Sonic Hedgehog.” PLoS Biology. Public Library of Science,
2010. https://doi.org/10.1371/journal.pbio.1000382.
ieee: É. Dessaud et al., “Dynamic assignment and maintenance of positional
identity in the ventral neural tube by the morphogen sonic hedgehog,” PLoS
Biology, vol. 8, no. 6. Public Library of Science, 2010.
ista: Dessaud É, Ribes V, Balaskas N, Yang L, Pierani A, Kicheva A, Novitch B, Briscoe
J, Sasai N. 2010. Dynamic assignment and maintenance of positional identity in
the ventral neural tube by the morphogen sonic hedgehog. PLoS Biology. 8(6).
mla: Dessaud, Éric, et al. “Dynamic Assignment and Maintenance of Positional Identity
in the Ventral Neural Tube by the Morphogen Sonic Hedgehog.” PLoS Biology,
vol. 8, no. 6, Public Library of Science, 2010, doi:10.1371/journal.pbio.1000382.
short: É. Dessaud, V. Ribes, N. Balaskas, L. Yang, A. Pierani, A. Kicheva, B. Novitch,
J. Briscoe, N. Sasai, PLoS Biology 8 (2010).
date_created: 2018-12-11T11:53:39Z
date_published: 2010-06-01T00:00:00Z
date_updated: 2021-01-12T06:52:46Z
day: '01'
doi: 10.1371/journal.pbio.1000382
extern: 1
intvolume: ' 8'
issue: '6'
month: '06'
publication: PLoS Biology
publication_status: published
publisher: Public Library of Science
publist_id: '5408'
quality_controlled: 0
status: public
title: Dynamic assignment and maintenance of positional identity in the ventral neural
tube by the morphogen sonic hedgehog
type: journal_article
volume: 8
year: '2010'
...
---
_id: '1752'
abstract:
- lang: eng
text: The epitaxial growth of germanium on silicon leads to the self-assembly of
SiGe nanocrystals by a process that allows the size, composition and position
of the nanocrystals to be controlled. This level of control, combined with an
inherent compatibility with silicon technology, could prove useful in nanoelectronic
applications. Here, we report the confinement of holes in quantum-dot devices
made by directly contacting individual SiGe nanocrystals with aluminium electrodes,
and the production of hybrid superconductor- semiconductor devices, such as resonant
supercurrent transistors, when the quantum dot is strongly coupled to the electrodes.
Charge transport measurements on weakly coupled quantum dots reveal discrete energy
spectra, with the confined hole states displaying anisotropic gyromagnetic factors
and strong spin-orbit coupling with pronounced dependences on gate voltage and
magnetic field.
acknowledgement: We also acknowledge support from the Agence Nationale de la Recherche
(through the ACCESS and COHESION projects). G.K. acknowledges further support from
the Deutsche Forschungsgemeinschaft (grant no. KA 2922/1-1)
author:
- first_name: Georgios
full_name: Georgios Katsaros
id: 38DB5788-F248-11E8-B48F-1D18A9856A87
last_name: Katsaros
- first_name: Panayotis
full_name: Spathis, Panayotis N
last_name: Spathis
- first_name: Mathieu
full_name: Stoffel, Mathieu
last_name: Stoffel
- first_name: Frank
full_name: Fournel, Frank
last_name: Fournel
- first_name: Massimo
full_name: Mongillo, Massimo
last_name: Mongillo
- first_name: Vincent
full_name: Bouchiat, Vincent
last_name: Bouchiat
- first_name: François
full_name: Lefloch, François
last_name: Lefloch
- first_name: Armando
full_name: Rastelli, Armando
last_name: Rastelli
- first_name: Oliver
full_name: Schmidt, Oliver G
last_name: Schmidt
- first_name: Silvano
full_name: De Franceschi, Silvano
last_name: De Franceschi
citation:
ama: Katsaros G, Spathis P, Stoffel M, et al. Hybrid superconductor-semiconductor
devices made from self-assembled SiGe nanocrystals on silicon. Nature Nanotechnology.
2010;5(6):458-464. doi:10.1038/nnano.2010.84
apa: Katsaros, G., Spathis, P., Stoffel, M., Fournel, F., Mongillo, M., Bouchiat,
V., … De Franceschi, S. (2010). Hybrid superconductor-semiconductor devices made
from self-assembled SiGe nanocrystals on silicon. Nature Nanotechnology.
Nature Publishing Group. https://doi.org/10.1038/nnano.2010.84
chicago: Katsaros, Georgios, Panayotis Spathis, Mathieu Stoffel, Frank Fournel,
Massimo Mongillo, Vincent Bouchiat, François Lefloch, Armando Rastelli, Oliver
Schmidt, and Silvano De Franceschi. “Hybrid Superconductor-Semiconductor Devices
Made from Self-Assembled SiGe Nanocrystals on Silicon.” Nature Nanotechnology.
Nature Publishing Group, 2010. https://doi.org/10.1038/nnano.2010.84.
ieee: G. Katsaros et al., “Hybrid superconductor-semiconductor devices made
from self-assembled SiGe nanocrystals on silicon,” Nature Nanotechnology,
vol. 5, no. 6. Nature Publishing Group, pp. 458–464, 2010.
ista: Katsaros G, Spathis P, Stoffel M, Fournel F, Mongillo M, Bouchiat V, Lefloch
F, Rastelli A, Schmidt O, De Franceschi S. 2010. Hybrid superconductor-semiconductor
devices made from self-assembled SiGe nanocrystals on silicon. Nature Nanotechnology.
5(6), 458–464.
mla: Katsaros, Georgios, et al. “Hybrid Superconductor-Semiconductor Devices Made
from Self-Assembled SiGe Nanocrystals on Silicon.” Nature Nanotechnology,
vol. 5, no. 6, Nature Publishing Group, 2010, pp. 458–64, doi:10.1038/nnano.2010.84.
short: G. Katsaros, P. Spathis, M. Stoffel, F. Fournel, M. Mongillo, V. Bouchiat,
F. Lefloch, A. Rastelli, O. Schmidt, S. De Franceschi, Nature Nanotechnology 5
(2010) 458–464.
date_created: 2018-12-11T11:53:49Z
date_published: 2010-06-01T00:00:00Z
date_updated: 2021-01-12T06:52:59Z
day: '01'
doi: 10.1038/nnano.2010.84
extern: 1
intvolume: ' 5'
issue: '6'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1005.1816
month: '06'
oa: 1
page: 458 - 464
publication: Nature Nanotechnology
publication_status: published
publisher: Nature Publishing Group
publist_id: '5372'
quality_controlled: 0
status: public
title: Hybrid superconductor-semiconductor devices made from self-assembled SiGe nanocrystals
on silicon
type: journal_article
volume: 5
year: '2010'
...
---
_id: '1753'
abstract:
- lang: eng
text: We investigate electronic transport in n-i-n GaN nanowires with and without
AlN double barriers. The nanowires are grown by catalyst-free, plasma-assisted
molecular beam epitaxy enabling abrupt GaN/AlN interfaces as well as longitudinal
n-type doping modulation. At low temperature, transport in n-i-n GaN nanowires
is dominated by the Coulomb blockade effect. Carriers are confined in the undoped
middle region, forming single or multiple islands with a characteristic length
of ∼100 nm. The incorporation of two AlN tunnel barriers causes confinement to
occur within the GaN dot in between. In the case of a 6 nm thick dot and 2 nm
thick barriers, we observe characteristic signatures of Coulomb-blockaded transport
in single quantum dots with discrete energy states. For thinner dots and barriers,
Coulomb-blockade effects do not play a significant role while the onset of resonant
tunneling via the confined quantum levels is accompanied by a negative differential
resistance surviving up to ∼150 K.
acknowledgement: This research was partly funded by the Agence Nationale de la Recherche
through the COHESION project. G.K. acknowledges further support from the Deutsche
Forschungsgemeinschaft (Grant KA 2922/1-1)
author:
- first_name: Rudeeson
full_name: Songmuang, Rudeeson
last_name: Songmuang
- first_name: Georgios
full_name: Georgios Katsaros
id: 38DB5788-F248-11E8-B48F-1D18A9856A87
last_name: Katsaros
- first_name: Eva
full_name: Monroy, Eva
last_name: Monroy
- first_name: Panayotis
full_name: Spathis, Panayotis N
last_name: Spathis
- first_name: Catherine
full_name: Bougerol, Catherine
last_name: Bougerol
- first_name: Massimo
full_name: Mongillo, Massimo
last_name: Mongillo
- first_name: Silvano
full_name: De Franceschi, Silvano
last_name: De Franceschi
citation:
ama: Songmuang R, Katsaros G, Monroy E, et al. Quantum transport in GaN/AlN double-barrier
heterostructure nanowires. Nano Letters. 2010;10(9):3545-3550. doi:10.1021/nl1017578
apa: Songmuang, R., Katsaros, G., Monroy, E., Spathis, P., Bougerol, C., Mongillo,
M., & De Franceschi, S. (2010). Quantum transport in GaN/AlN double-barrier
heterostructure nanowires. Nano Letters. American Chemical Society. https://doi.org/10.1021/nl1017578
chicago: Songmuang, Rudeeson, Georgios Katsaros, Eva Monroy, Panayotis Spathis,
Catherine Bougerol, Massimo Mongillo, and Silvano De Franceschi. “Quantum Transport
in GaN/AlN Double-Barrier Heterostructure Nanowires.” Nano Letters. American
Chemical Society, 2010. https://doi.org/10.1021/nl1017578.
ieee: R. Songmuang et al., “Quantum transport in GaN/AlN double-barrier heterostructure
nanowires,” Nano Letters, vol. 10, no. 9. American Chemical Society, pp.
3545–3550, 2010.
ista: Songmuang R, Katsaros G, Monroy E, Spathis P, Bougerol C, Mongillo M, De Franceschi
S. 2010. Quantum transport in GaN/AlN double-barrier heterostructure nanowires.
Nano Letters. 10(9), 3545–3550.
mla: Songmuang, Rudeeson, et al. “Quantum Transport in GaN/AlN Double-Barrier Heterostructure
Nanowires.” Nano Letters, vol. 10, no. 9, American Chemical Society, 2010,
pp. 3545–50, doi:10.1021/nl1017578.
short: R. Songmuang, G. Katsaros, E. Monroy, P. Spathis, C. Bougerol, M. Mongillo,
S. De Franceschi, Nano Letters 10 (2010) 3545–3550.
date_created: 2018-12-11T11:53:49Z
date_published: 2010-09-08T00:00:00Z
date_updated: 2021-01-12T06:52:59Z
day: '08'
doi: 10.1021/nl1017578
extern: 1
intvolume: ' 10'
issue: '9'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1005.3637
month: '09'
oa: 1
page: 3545 - 3550
publication: Nano Letters
publication_status: published
publisher: American Chemical Society
publist_id: '5371'
quality_controlled: 0
status: public
title: Quantum transport in GaN/AlN double-barrier heterostructure nanowires
type: journal_article
volume: 10
year: '2010'
...
---
_id: '1772'
abstract:
- lang: eng
text: We present the realization of a cavity quantum electrodynamics setup in which
photons of strongly different lifetimes are engineered in different harmonic modes
of the same cavity. We achieve this in a superconducting transmission line resonator
with superconducting qubits coupled to the different modes. One cavity mode is
strongly coupled to a detection line for qubit state readout, while a second long
lifetime mode is used for photon storage and coherent quantum operations. We demonstrate
sideband-based measurement of photon coherence, generation of n photon Fock states
and the scaling of the sideband Rabi frequency with √n using a scheme that may
be extended to realize sideband-based two-qubit logic gates.
acknowledgement: This work was supported financially by the Swiss National Science
Foundation, by the EC via the EuroSQIP project and by ETH Zurich
author:
- first_name: Peter
full_name: Leek, Peter J
last_name: Leek
- first_name: Matthias
full_name: Baur, Matthias P
last_name: Baur
- first_name: Johannes M
full_name: Johannes Fink
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
- first_name: R
full_name: Bianchetti, R
last_name: Bianchetti
- first_name: L.
full_name: Steffen, L. Kraig
last_name: Steffen
- first_name: Stefan
full_name: Filipp, Stefan
last_name: Filipp
- first_name: Andreas
full_name: Wallraff, Andreas
last_name: Wallraff
citation:
ama: Leek P, Baur M, Fink JM, et al. Cavity quantum electrodynamics with separate
photon storage and qubit readout modes. Physical Review Letters. 2010;104(10).
doi:10.1103/PhysRevLett.104.100504
apa: Leek, P., Baur, M., Fink, J. M., Bianchetti, R., Steffen, L., Filipp, S., &
Wallraff, A. (2010). Cavity quantum electrodynamics with separate photon storage
and qubit readout modes. Physical Review Letters. American Physical Society.
https://doi.org/10.1103/PhysRevLett.104.100504
chicago: Leek, Peter, Matthias Baur, Johannes M Fink, R Bianchetti, L. Steffen,
Stefan Filipp, and Andreas Wallraff. “Cavity Quantum Electrodynamics with Separate
Photon Storage and Qubit Readout Modes.” Physical Review Letters. American
Physical Society, 2010. https://doi.org/10.1103/PhysRevLett.104.100504.
ieee: P. Leek et al., “Cavity quantum electrodynamics with separate photon
storage and qubit readout modes,” Physical Review Letters, vol. 104, no.
10. American Physical Society, 2010.
ista: Leek P, Baur M, Fink JM, Bianchetti R, Steffen L, Filipp S, Wallraff A. 2010.
Cavity quantum electrodynamics with separate photon storage and qubit readout
modes. Physical Review Letters. 104(10).
mla: Leek, Peter, et al. “Cavity Quantum Electrodynamics with Separate Photon Storage
and Qubit Readout Modes.” Physical Review Letters, vol. 104, no. 10, American
Physical Society, 2010, doi:10.1103/PhysRevLett.104.100504.
short: P. Leek, M. Baur, J.M. Fink, R. Bianchetti, L. Steffen, S. Filipp, A. Wallraff,
Physical Review Letters 104 (2010).
date_created: 2018-12-11T11:53:55Z
date_published: 2010-03-10T00:00:00Z
date_updated: 2021-01-12T06:53:06Z
day: '10'
doi: 10.1103/PhysRevLett.104.100504
extern: 1
intvolume: ' 104'
issue: '10'
month: '03'
publication: Physical Review Letters
publication_status: published
publisher: American Physical Society
publist_id: '5345'
quality_controlled: 0
status: public
title: Cavity quantum electrodynamics with separate photon storage and qubit readout
modes
type: journal_article
volume: 104
year: '2010'
...
---
_id: '1773'
abstract:
- lang: eng
text: The quantum properties of electromagnetic, mechanical or other harmonic oscillators
can be revealed by investigating their strong coherent coupling to a single quantum
two level system in an approach known as cavity quantum electrodynamics (QED).
At temperatures much lower than the characteristic energy level spacing the observation
of vacuum Rabi oscillations or mode splittings with one or a few quanta asserts
the quantum nature of the oscillator. Here, we study how the classical response
of a cavity QED system emerges from the quantum one when its thermal occupation-or
effective temperature-is raised gradually over 5 orders of magnitude. In this
way we explore in detail the continuous quantum-to-classical crossover and demonstrate
how to extract effective cavity field temperatures from both spectroscopic and
time-resolved vacuum Rabi measurements.
acknowledgement: This work was supported by SNF, EuroSQIP and ETHZ. L. S. B. acknowledges
support by LPS/NSA under ARO contract No. W911NF-05-1-0365 and the NSF under grant
No. DMR-0653377
author:
- first_name: Johannes M
full_name: Johannes Fink
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
- first_name: L.
full_name: Steffen, L. Kraig
last_name: Steffen
- first_name: Peter
full_name: Studer, Peter
last_name: Studer
- first_name: Lev
full_name: Bishop, Lev S
last_name: Bishop
- first_name: Matthias
full_name: Baur, Matthias P
last_name: Baur
- first_name: R
full_name: Bianchetti, R
last_name: Bianchetti
- first_name: Deniz
full_name: Bozyigit, Deniz
last_name: Bozyigit
- first_name: C
full_name: Lang, C
last_name: Lang
- first_name: Stefan
full_name: Filipp, Stefan
last_name: Filipp
- first_name: Peter
full_name: Leek, Peter J
last_name: Leek
- first_name: Andreas
full_name: Wallraff, Andreas
last_name: Wallraff
citation:
ama: Fink JM, Steffen L, Studer P, et al. Quantum-to-classical transition in cavity
quantum electrodynamics. Physical Review Letters. 2010;105(16). doi:10.1103/PhysRevLett.105.163601
apa: Fink, J. M., Steffen, L., Studer, P., Bishop, L., Baur, M., Bianchetti, R.,
… Wallraff, A. (2010). Quantum-to-classical transition in cavity quantum electrodynamics.
Physical Review Letters. American Physical Society. https://doi.org/10.1103/PhysRevLett.105.163601
chicago: Fink, Johannes M, L. Steffen, Peter Studer, Lev Bishop, Matthias Baur,
R Bianchetti, Deniz Bozyigit, et al. “Quantum-to-Classical Transition in Cavity
Quantum Electrodynamics.” Physical Review Letters. American Physical Society,
2010. https://doi.org/10.1103/PhysRevLett.105.163601.
ieee: J. M. Fink et al., “Quantum-to-classical transition in cavity quantum
electrodynamics,” Physical Review Letters, vol. 105, no. 16. American Physical
Society, 2010.
ista: Fink JM, Steffen L, Studer P, Bishop L, Baur M, Bianchetti R, Bozyigit D,
Lang C, Filipp S, Leek P, Wallraff A. 2010. Quantum-to-classical transition in
cavity quantum electrodynamics. Physical Review Letters. 105(16).
mla: Fink, Johannes M., et al. “Quantum-to-Classical Transition in Cavity Quantum
Electrodynamics.” Physical Review Letters, vol. 105, no. 16, American Physical
Society, 2010, doi:10.1103/PhysRevLett.105.163601.
short: J.M. Fink, L. Steffen, P. Studer, L. Bishop, M. Baur, R. Bianchetti, D. Bozyigit,
C. Lang, S. Filipp, P. Leek, A. Wallraff, Physical Review Letters 105 (2010).
date_created: 2018-12-11T11:53:56Z
date_published: 2010-10-14T00:00:00Z
date_updated: 2021-01-12T06:53:07Z
day: '14'
doi: 10.1103/PhysRevLett.105.163601
extern: 1
intvolume: ' 105'
issue: '16'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1003.1161
month: '10'
oa: 1
publication: Physical Review Letters
publication_status: published
publisher: American Physical Society
publist_id: '5343'
quality_controlled: 0
status: public
title: Quantum-to-classical transition in cavity quantum electrodynamics
type: journal_article
volume: 105
year: '2010'
...
---
_id: '1774'
abstract:
- lang: eng
text: A number of superconducting qubits, such as the transmon or the phase qubit,
have an energy level structure with small anharmonicity. This allows for convenient
access of higher excited states with similar frequencies. However, special care
has to be taken to avoid unwanted higher-level populations when using short control
pulses. Here we demonstrate the preparation of arbitrary three level superposition
states using optimal control techniques in a transmon. Performing dispersive readout,
we extract the populations of all three levels of the qutrit and study the coherence
of its excited states. Finally we demonstrate full quantum state tomography of
the prepared qutrit states and evaluate the fidelities of a set of states, finding
on average 95%.
acknowledgement: This work was supported by SNF, ETHZ, the Austrian Science Foundation
(FWF), and the EU projects SOLID and GEOMDISS. A. B. is supported by NSERC, the
Alfred P. Sloan Foundation, and CIFAR
author:
- first_name: R
full_name: Bianchetti, R
last_name: Bianchetti
- first_name: Stefan
full_name: Filipp, Stefan
last_name: Filipp
- first_name: Matthias
full_name: Baur, Matthias P
last_name: Baur
- first_name: Johannes M
full_name: Johannes Fink
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
- first_name: C
full_name: Lang, C
last_name: Lang
- first_name: L.
full_name: Steffen, L. Kraig
last_name: Steffen
- first_name: Maxime
full_name: Boissonneault, Maxime
last_name: Boissonneault
- first_name: Alexandre
full_name: Blais, Alexandre
last_name: Blais
- first_name: Andreas
full_name: Wallraff, Andreas
last_name: Wallraff
citation:
ama: Bianchetti R, Filipp S, Baur M, et al. Control and tomography of a three level
superconducting artificial atom. Physical Review Letters. 2010;105(22).
doi:10.1103/PhysRevLett.105.223601
apa: Bianchetti, R., Filipp, S., Baur, M., Fink, J. M., Lang, C., Steffen, L., …
Wallraff, A. (2010). Control and tomography of a three level superconducting artificial
atom. Physical Review Letters. American Physical Society. https://doi.org/10.1103/PhysRevLett.105.223601
chicago: Bianchetti, R, Stefan Filipp, Matthias Baur, Johannes M Fink, C Lang, L.
Steffen, Maxime Boissonneault, Alexandre Blais, and Andreas Wallraff. “Control
and Tomography of a Three Level Superconducting Artificial Atom.” Physical
Review Letters. American Physical Society, 2010. https://doi.org/10.1103/PhysRevLett.105.223601.
ieee: R. Bianchetti et al., “Control and tomography of a three level superconducting
artificial atom,” Physical Review Letters, vol. 105, no. 22. American Physical
Society, 2010.
ista: Bianchetti R, Filipp S, Baur M, Fink JM, Lang C, Steffen L, Boissonneault
M, Blais A, Wallraff A. 2010. Control and tomography of a three level superconducting
artificial atom. Physical Review Letters. 105(22).
mla: Bianchetti, R., et al. “Control and Tomography of a Three Level Superconducting
Artificial Atom.” Physical Review Letters, vol. 105, no. 22, American Physical
Society, 2010, doi:10.1103/PhysRevLett.105.223601.
short: R. Bianchetti, S. Filipp, M. Baur, J.M. Fink, C. Lang, L. Steffen, M. Boissonneault,
A. Blais, A. Wallraff, Physical Review Letters 105 (2010).
date_created: 2018-12-11T11:53:56Z
date_published: 2010-11-24T00:00:00Z
date_updated: 2021-01-12T06:53:07Z
day: '24'
doi: 10.1103/PhysRevLett.105.223601
extern: 1
intvolume: ' 105'
issue: '22'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1004.5504
month: '11'
oa: 1
publication: Physical Review Letters
publication_status: published
publisher: American Physical Society
publist_id: '5341'
quality_controlled: 0
status: public
title: Control and tomography of a three level superconducting artificial atom
type: journal_article
volume: 105
year: '2010'
...
---
_id: '1800'
abstract:
- lang: eng
text: Retinitis pigmentosa refers to a diverse group of hereditary diseases that
lead to incurable blindness, affecting two million people worldwide. As a common
pathology, rod photoreceptors die early, whereas light-insensitive, morphologically
altered cone photoreceptors persist longer. It is unknown if these cones are accessible
for therapeutic intervention. Here, we show that expression of archaebacterial
halorhodopsin in light-insensitive cones can substitute for the native phototransduction
cascade and restore light sensitivity in mouse models of retinitis pigmentosa.
Resensitized photoreceptors activate all retinal cone pathways, drive sophisticated
retinal circuit functions (including directional selectivity), activate cortical
circuits, and mediate visually guided behaviors. Using human ex vivo retinas,
we show that halorhodopsin can reactivate light-insensitive human photoreceptors.
Finally, we identified blind patients with persisting, light-insensitive cones
for potential halorhodopsin-based therapy.
acknowledgement: This study was supported by Friedrich Miescher Institute funds; a
U.S. Office of Naval Research Naval International Cooperative Opportunities in Science
and Technology Program grant; a Marie Curie Excellence grant and a European Union
(EU) HEALTH-F2-223156 grant to B.R.; a grant from the EU (RETICIRC) to B.R. and
S.P.; grants from the Agence nationale de la recherche (MEDINAS, RETINE) to S.P.;
a Center Grant from Foundation Fighting Blindness (U.S.) to S.M.-S. and J.A.S.;
grants from the Swiss National Science Foundation and the EU to D.T.; a grant from
the EU (TREATRUSH) to J.A.S., S.P., and B.R.; a Marie Curie Postdoctoral Fellowship
to D.B.; and a National Centers of Competence in Research Frontiers in Genetics
fellowship to V.B. and A.C.G. The Ocular Genetics Unit at Trinity College Dublin
is supported by Science Foundation Ireland
author:
- first_name: Volker
full_name: Busskamp, Volker
last_name: Busskamp
- first_name: Jens
full_name: Duebel, Jens
last_name: Duebel
- first_name: Dávid
full_name: Bálya, Dávid
last_name: Bálya
- first_name: Mathias
full_name: Fradot, Mathias
last_name: Fradot
- first_name: Tim
full_name: Viney, Tim J
last_name: Viney
- first_name: Sandra
full_name: Sandra Siegert
id: 36ACD32E-F248-11E8-B48F-1D18A9856A87
last_name: Siegert
orcid: 0000-0001-8635-0877
- first_name: Anna
full_name: Groner, Anna C
last_name: Groner
- first_name: Erik
full_name: Cabuy, Erik
last_name: Cabuy
- first_name: Valérie
full_name: Forster, Valérie
last_name: Forster
- first_name: Mathias
full_name: Seeliger, Mathias W
last_name: Seeliger
- first_name: Martin
full_name: Biel, Martin
last_name: Biel
- first_name: Peter
full_name: Humphries, Peter
last_name: Humphries
- first_name: Michel
full_name: Pâques, Michel
last_name: Pâques
- first_name: Saddek
full_name: Mohand-Saïd, Saddek
last_name: Mohand Saïd
- first_name: Didier
full_name: Trono, Didier
last_name: Trono
- first_name: Karl
full_name: Deisseroth, Karl A
last_name: Deisseroth
- first_name: José
full_name: Sähel, José A
last_name: Sähel
- first_name: Serge
full_name: Picaud, Serge A
last_name: Picaud
- first_name: Botond
full_name: Roska, Botond M
last_name: Roska
citation:
ama: Busskamp V, Duebel J, Bálya D, et al. Genetic reactivation of cone photoreceptors
restores visual responses in retinitis pigmentosa. Science. 2010;329(5990):413-417.
doi:10.1126/science.1190897
apa: Busskamp, V., Duebel, J., Bálya, D., Fradot, M., Viney, T., Siegert, S., …
Roska, B. (2010). Genetic reactivation of cone photoreceptors restores visual
responses in retinitis pigmentosa. Science. American Association for the
Advancement of Science. https://doi.org/10.1126/science.1190897
chicago: Busskamp, Volker, Jens Duebel, Dávid Bálya, Mathias Fradot, Tim Viney,
Sandra Siegert, Anna Groner, et al. “Genetic Reactivation of Cone Photoreceptors
Restores Visual Responses in Retinitis Pigmentosa.” Science. American Association
for the Advancement of Science, 2010. https://doi.org/10.1126/science.1190897.
ieee: V. Busskamp et al., “Genetic reactivation of cone photoreceptors restores
visual responses in retinitis pigmentosa,” Science, vol. 329, no. 5990.
American Association for the Advancement of Science, pp. 413–417, 2010.
ista: Busskamp V, Duebel J, Bálya D, Fradot M, Viney T, Siegert S, Groner A, Cabuy
E, Forster V, Seeliger M, Biel M, Humphries P, Pâques M, Mohand Saïd S, Trono
D, Deisseroth K, Sähel J, Picaud S, Roska B. 2010. Genetic reactivation of cone
photoreceptors restores visual responses in retinitis pigmentosa. Science. 329(5990),
413–417.
mla: Busskamp, Volker, et al. “Genetic Reactivation of Cone Photoreceptors Restores
Visual Responses in Retinitis Pigmentosa.” Science, vol. 329, no. 5990,
American Association for the Advancement of Science, 2010, pp. 413–17, doi:10.1126/science.1190897.
short: V. Busskamp, J. Duebel, D. Bálya, M. Fradot, T. Viney, S. Siegert, A. Groner,
E. Cabuy, V. Forster, M. Seeliger, M. Biel, P. Humphries, M. Pâques, S. Mohand
Saïd, D. Trono, K. Deisseroth, J. Sähel, S. Picaud, B. Roska, Science 329 (2010)
413–417.
date_created: 2018-12-11T11:54:05Z
date_published: 2010-07-23T00:00:00Z
date_updated: 2021-01-12T06:53:17Z
day: '23'
doi: 10.1126/science.1190897
extern: 1
intvolume: ' 329'
issue: '5990'
month: '07'
page: 413 - 417
publication: Science
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '5310'
quality_controlled: 0
status: public
title: Genetic reactivation of cone photoreceptors restores visual responses in retinitis
pigmentosa
type: journal_article
volume: 329
year: '2010'
...
---
_id: '1970'
abstract:
- lang: eng
text: 'Complex I is the first enzyme of the respiratory chain and has a central
role in cellular energy production, coupling electron transfer between NADH and
quinone to proton translocation by an unknown mechanism. Dysfunction of complex
I has been implicated in many human neurodegenerative diseases. We have determined
the structure of its hydrophilic domain previously. Here, we report the α-helical
structure of the membrane domain of complex I from Escherichia coli at 3.9 Å resolution.
The antiporter-like subunits NuoL/M/N each contain 14 conserved transmembrane
(TM) helices. Two of them are discontinuous, as in some transporters. Unexpectedly,
subunit NuoL also contains a 110-Å long amphipathic α-helix, spanning almost the
entire length of the domain. Furthermore, we have determined the structure of
the entire complex I from Thermus thermophilus at 4.5 Å resolution. The L-shaped
assembly consists of the α-helical model for the membrane domain, with 63 TM helices,
and the known structure of the hydrophilic domain. The architecture of the complex
provides strong clues about the coupling mechanism: the conformational changes
at the interface of the two main domains may drive the long amphipathic α-helix
of NuoL in a piston-like motion, tilting nearby discontinuous TM helices, resulting
in proton translocation.'
acknowledgement: This work was funded by the Medical Research Council.
author:
- first_name: Rouslan
full_name: Efremov, Rouslan G
last_name: Efremov
- first_name: Rozbeh
full_name: 'Baradaran, Rozbeh '
last_name: Baradaran
- first_name: Leonid A
full_name: Leonid Sazanov
id: 338D39FE-F248-11E8-B48F-1D18A9856A87
last_name: Sazanov
orcid: 0000-0002-0977-7989
citation:
ama: Efremov R, Baradaran R, Sazanov LA. The architecture of respiratory complex
I. Nature. 2010;465(7297):441-445. doi:10.1038/nature09066
apa: Efremov, R., Baradaran, R., & Sazanov, L. A. (2010). The architecture of
respiratory complex I. Nature. Nature Publishing Group. https://doi.org/10.1038/nature09066
chicago: Efremov, Rouslan, Rozbeh Baradaran, and Leonid A Sazanov. “The Architecture
of Respiratory Complex I.” Nature. Nature Publishing Group, 2010. https://doi.org/10.1038/nature09066.
ieee: R. Efremov, R. Baradaran, and L. A. Sazanov, “The architecture of respiratory
complex I,” Nature, vol. 465, no. 7297. Nature Publishing Group, pp. 441–445,
2010.
ista: Efremov R, Baradaran R, Sazanov LA. 2010. The architecture of respiratory
complex I. Nature. 465(7297), 441–445.
mla: Efremov, Rouslan, et al. “The Architecture of Respiratory Complex I.” Nature,
vol. 465, no. 7297, Nature Publishing Group, 2010, pp. 441–45, doi:10.1038/nature09066.
short: R. Efremov, R. Baradaran, L.A. Sazanov, Nature 465 (2010) 441–445.
date_created: 2018-12-11T11:54:58Z
date_published: 2010-05-27T00:00:00Z
date_updated: 2021-01-12T06:54:25Z
day: '27'
doi: 10.1038/nature09066
extern: 1
intvolume: ' 465'
issue: '7297'
month: '05'
page: 441 - 445
publication: Nature
publication_status: published
publisher: Nature Publishing Group
publist_id: '5113'
quality_controlled: 0
status: public
title: The architecture of respiratory complex I
type: journal_article
volume: 465
year: '2010'
...
---
_id: '2071'
abstract:
- lang: eng
text: The X or Z chromosome has several characteristics that distinguish it from
the autosomes, namely hemizygosity in the heterogametic sex, and a potentially
different effective population size, both of which may influence the rate and
nature of evolution. In particular, there may be an accelerated rate of adaptive
change for X-linked compared to autosomal coding sequences, often referred to
as the Faster-X effect. Empirical studies have indicated that the strength of
Faster-X evolution varies among different species, and theoretical treatments
have shown that demography and mating system can substantially affect the degree
of Faster-X evolution. Here we integrate genomic data on Faster-X evolution from
a variety of animals with the demographic factors, mating system, and sex chromosome
regulatory characteristics that may influence it. Our results suggest that differences
in effective population size and mechanisms of dosage compensation may influence
the perceived extent of Faster-X evolution, and help to explain several clade-specific
patterns that we observe.
acknowledgement: We gratefully acknowledge funding from the Royal Society (to JEM)
author:
- first_name: Judith
full_name: Mank, Judith E
last_name: Mank
- first_name: Beatriz
full_name: Beatriz Vicoso
id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
last_name: Vicoso
orcid: 0000-0002-4579-8306
- first_name: Sofia
full_name: Berlin, Sofia
last_name: Berlin
- first_name: Brian
full_name: Charlesworth, Brian
last_name: Charlesworth
citation:
ama: 'Mank J, Vicoso B, Berlin S, Charlesworth B. Effective population size and
the Faster-X effect: Empirical results and their interpretation. Evolution.
2010;64(3):663-674. doi:10.1111/j.1558-5646.2009.00853.x'
apa: 'Mank, J., Vicoso, B., Berlin, S., & Charlesworth, B. (2010). Effective
population size and the Faster-X effect: Empirical results and their interpretation.
Evolution. Wiley-Blackwell. https://doi.org/10.1111/j.1558-5646.2009.00853.x'
chicago: 'Mank, Judith, Beatriz Vicoso, Sofia Berlin, and Brian Charlesworth. “Effective
Population Size and the Faster-X Effect: Empirical Results and Their Interpretation.”
Evolution. Wiley-Blackwell, 2010. https://doi.org/10.1111/j.1558-5646.2009.00853.x.'
ieee: 'J. Mank, B. Vicoso, S. Berlin, and B. Charlesworth, “Effective population
size and the Faster-X effect: Empirical results and their interpretation,” Evolution,
vol. 64, no. 3. Wiley-Blackwell, pp. 663–674, 2010.'
ista: 'Mank J, Vicoso B, Berlin S, Charlesworth B. 2010. Effective population size
and the Faster-X effect: Empirical results and their interpretation. Evolution.
64(3), 663–674.'
mla: 'Mank, Judith, et al. “Effective Population Size and the Faster-X Effect: Empirical
Results and Their Interpretation.” Evolution, vol. 64, no. 3, Wiley-Blackwell,
2010, pp. 663–74, doi:10.1111/j.1558-5646.2009.00853.x.'
short: J. Mank, B. Vicoso, S. Berlin, B. Charlesworth, Evolution 64 (2010) 663–674.
date_created: 2018-12-11T11:55:32Z
date_published: 2010-03-01T00:00:00Z
date_updated: 2021-01-12T06:55:07Z
day: '01'
doi: 10.1111/j.1558-5646.2009.00853.x
extern: 1
intvolume: ' 64'
issue: '3'
month: '03'
page: 663 - 674
publication: Evolution
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4967'
quality_controlled: 0
status: public
title: 'Effective population size and the Faster-X effect: Empirical results and their
interpretation'
type: journal_article
volume: 64
year: '2010'
...
---
_id: '2075'
abstract:
- lang: eng
text: "This thesis investigates the combination of data-driven and physically based
techniques for acquiring, modeling, and animating deformable materials, with a
special focus on human faces. Furthermore, based on these techniques, we introduce
a data-driven process for designing and fabricating materials with desired deformation
behavior. \nRealistic simulation behavior, surface details, and appearance are
still demanding tasks. Neither pure data-driven, pure procedural, nor pure physical
methods are best suited for accurate synthesis of facial motion and details (both
for appearance and geometry), due to the difficulties in model design, parameter
estimation, and desired controllability for animators. Capturing of a small but
representative amount of real data, and then synthesizing diverse on-demand examples
with physically-based models and real data as input benefits from both sides:
Highly realistic model behavior due to real-world data and controllability due
to physically-based models.\nTo model the face and its behavior, hybrid physically-based
and data-driven approaches are elaborated. We investigate surface-based representations
as well as a solid representation based on FEM. To achieve realistic behavior,
we propose to build light-weighted data capture devices to acquire real-world
data to estimate model parameters and to employ concepts from data-driven modeling
techniques and machine learning. The resulting models support simple acquisition
systems, offer techniques to process and extract model parameters from real-world
data, provide a compact representation of the facial geometry and its motion,
and allow intuitive editing. We demonstrate applications such as capture of facial
geometry and motion and real-time animation and transfer of facial details, and
show that our soft tissue model can react to external forces and produce realistic
deformations beyond facial expressions.\nBased on this model, we furthermore introduce
a data-driven process for designing and fabricating materials with desired deformation
behavior. The process starts with measuring deformation properties of base materials.
Each material is represented as a non-linear stress-strain relationship in a finite-element
model. For material design and fabrication, we introduce an optimization process
that finds the best combination of base materials that meets a user’s criteria
specified by example deformations. Our algorithm employs a number of strategies
to prune poor solutions from the combinatorial search space. We finally demonstrate
the complete process by designing and fabricating objects with complex heterogeneous
materials using modern multi-material 3D printers.\n"
author:
- first_name: Bernd
full_name: Bernd Bickel
id: 49876194-F248-11E8-B48F-1D18A9856A87
last_name: Bickel
orcid: 0000-0001-6511-9385
citation:
ama: Bickel B. Measurement-based modeling and fabrication of deformable materials
for human faces. Unknown. 2010;499(7458). doi:dx.doi.org/10.3929/ethz-a-006354908
apa: Bickel, B. (2010). Measurement-based modeling and fabrication of deformable
materials for human faces. Unknown. Unknown. https://doi.org/dx.doi.org/10.3929/ethz-a-006354908
chicago: Bickel, Bernd. “Measurement-Based Modeling and Fabrication of Deformable
Materials for Human Faces.” Unknown. Unknown, 2010. https://doi.org/dx.doi.org/10.3929/ethz-a-006354908.
ieee: B. Bickel, “Measurement-based modeling and fabrication of deformable materials
for human faces,” Unknown, 2010.
ista: Bickel B. 2010. Measurement-based modeling and fabrication of deformable materials
for human faces. Unknown.
mla: Bickel, Bernd. “Measurement-Based Modeling and Fabrication of Deformable Materials
for Human Faces.” Unknown, vol. 499, no. 7458, Unknown, 2010, doi:dx.doi.org/10.3929/ethz-a-006354908.
short: B. Bickel, Measurement-Based Modeling and Fabrication of Deformable Materials
for Human Faces, Unknown, 2010.
date_created: 2018-12-11T11:55:34Z
date_published: 2010-01-01T00:00:00Z
date_updated: 2021-01-12T06:55:09Z
day: '01'
doi: dx.doi.org/10.3929/ethz-a-006354908
extern: 1
intvolume: ' 499'
issue: '7458'
month: '01'
publication: Unknown
publication_status: published
publisher: Unknown
publist_id: '4963'
quality_controlled: 0
status: public
title: Measurement-based modeling and fabrication of deformable materials for human
faces
type: dissertation
volume: 499
year: '2010'
...
---
_id: '2095'
abstract:
- lang: eng
text: This paper describes a passive stereo system for capturing the 3D geometry
of a face in a single-shot under standard light sources. The system is low-cost
and easy to deploy. Results are submillimeter accurate and commensurate with those
from state-ofthe-art systems based on active lighting, and the models meet the
quality requirements of a demanding domain like the movie industry. Recovered
models are shown for captures from both high-end cameras in a studio setting and
from a consumer binocular-stereo camera, demonstrating scalability across a spectrum
of camera deployments, and showing the potential for 3D face modeling to move
beyond the professional arena and into the emerging consumer market in stereoscopic
photography. Our primary technical contribution is a modification of standard
stereo refinement methods to capture pore-scale geometry, using a qualitative
approach that produces visually realistic results. The second technical contribution
is a calibration method suited to face capture systems. The systemic contribution
includes multiple demonstrations of system robustness and quality. These include
capture in a studio setup, capture off a consumer binocular-stereo camera, scanning
of faces of varying gender and ethnicity and age, capture of highly-transient
facial expression, and scanning a physical mask to provide ground-truth validation.
author:
- first_name: Thabo
full_name: Beeler, Thabo
last_name: Beeler
- first_name: Bernd
full_name: Bernd Bickel
id: 49876194-F248-11E8-B48F-1D18A9856A87
last_name: Bickel
orcid: 0000-0001-6511-9385
- first_name: Paul
full_name: Beardsley, Paul A
last_name: Beardsley
- first_name: Bob
full_name: Sumner, Bob
last_name: Sumner
- first_name: Markus
full_name: Groß, Markus S
last_name: Groß
citation:
ama: Beeler T, Bickel B, Beardsley P, Sumner B, Groß M. High-quality single-shot
capture of facial geometry. ACM Transactions on Graphics. 2010;29(4). doi:10.1145/1778765.1778777
apa: Beeler, T., Bickel, B., Beardsley, P., Sumner, B., & Groß, M. (2010). High-quality
single-shot capture of facial geometry. ACM Transactions on Graphics. ACM.
https://doi.org/10.1145/1778765.1778777
chicago: Beeler, Thabo, Bernd Bickel, Paul Beardsley, Bob Sumner, and Markus Groß.
“High-Quality Single-Shot Capture of Facial Geometry.” ACM Transactions on
Graphics. ACM, 2010. https://doi.org/10.1145/1778765.1778777.
ieee: T. Beeler, B. Bickel, P. Beardsley, B. Sumner, and M. Groß, “High-quality
single-shot capture of facial geometry,” ACM Transactions on Graphics,
vol. 29, no. 4. ACM, 2010.
ista: Beeler T, Bickel B, Beardsley P, Sumner B, Groß M. 2010. High-quality single-shot
capture of facial geometry. ACM Transactions on Graphics. 29(4).
mla: Beeler, Thabo, et al. “High-Quality Single-Shot Capture of Facial Geometry.”
ACM Transactions on Graphics, vol. 29, no. 4, ACM, 2010, doi:10.1145/1778765.1778777.
short: T. Beeler, B. Bickel, P. Beardsley, B. Sumner, M. Groß, ACM Transactions
on Graphics 29 (2010).
date_created: 2018-12-11T11:55:41Z
date_published: 2010-01-01T00:00:00Z
date_updated: 2021-01-12T06:55:16Z
day: '01'
doi: 10.1145/1778765.1778777
extern: 1
intvolume: ' 29'
issue: '4'
main_file_link:
- open_access: '1'
url: http://e-collection.library.ethz.ch/view/eth:5079
month: '01'
oa: 1
publication: ACM Transactions on Graphics
publication_status: published
publisher: ACM
publist_id: '4938'
quality_controlled: 0
status: public
title: High-quality single-shot capture of facial geometry
type: journal_article
volume: 29
year: '2010'
...
---
_id: '2096'
abstract:
- lang: eng
text: Point-based graphics has gained much attention as an alternative to polygon-based
approaches because of its simplicity and flexibility. However, current point-based
techniques do not provide a sufficient rendering quality for translucent materials
such as human skin. In this paper, we propose a point-based framework with subsurface
scattering of light, which is important to create the soft and semi-translucent
appearance of human skin. To accurately simulate subsurface scattering in multilayered
materials, we present splat-based diffusion to apply a linear combination of several
Gaussian basis functions to each splat in object space. Compared to existing point-based
approaches, our method offers a significantly improved visual quality in rendering
human faces and provides a similar visual quality to polygon-based rendering using
the texture space diffusion technique. We demonstrate the effectiveness of our
approach in rendering scanned faces realistically.
author:
- first_name: Hyeonjoong
full_name: Kim, Hyeonjoong
last_name: Kim
- first_name: Bernd
full_name: Bernd Bickel
id: 49876194-F248-11E8-B48F-1D18A9856A87
last_name: Bickel
orcid: 0000-0001-6511-9385
- first_name: Markus
full_name: Groß, Markus S
last_name: Groß
- first_name: Soomi
full_name: Choi, Soomi
last_name: Choi
citation:
ama: 'Kim H, Bickel B, Groß M, Choi S. Subsurface scattering using splat-based diffusion
in point-based rendering. Science in China, Series F: Information Sciences.
2010;53(5):911-919. doi:10.1007/s11432-010-0068-y'
apa: 'Kim, H., Bickel, B., Groß, M., & Choi, S. (2010). Subsurface scattering
using splat-based diffusion in point-based rendering. Science in China, Series
F: Information Sciences. Springer. https://doi.org/10.1007/s11432-010-0068-y'
chicago: 'Kim, Hyeonjoong, Bernd Bickel, Markus Groß, and Soomi Choi. “Subsurface
Scattering Using Splat-Based Diffusion in Point-Based Rendering.” Science in
China, Series F: Information Sciences. Springer, 2010. https://doi.org/10.1007/s11432-010-0068-y.'
ieee: 'H. Kim, B. Bickel, M. Groß, and S. Choi, “Subsurface scattering using splat-based
diffusion in point-based rendering,” Science in China, Series F: Information
Sciences, vol. 53, no. 5. Springer, pp. 911–919, 2010.'
ista: 'Kim H, Bickel B, Groß M, Choi S. 2010. Subsurface scattering using splat-based
diffusion in point-based rendering. Science in China, Series F: Information Sciences.
53(5), 911–919.'
mla: 'Kim, Hyeonjoong, et al. “Subsurface Scattering Using Splat-Based Diffusion
in Point-Based Rendering.” Science in China, Series F: Information Sciences,
vol. 53, no. 5, Springer, 2010, pp. 911–19, doi:10.1007/s11432-010-0068-y.'
short: 'H. Kim, B. Bickel, M. Groß, S. Choi, Science in China, Series F: Information
Sciences 53 (2010) 911–919.'
date_created: 2018-12-11T11:55:41Z
date_published: 2010-04-14T00:00:00Z
date_updated: 2021-01-12T06:55:16Z
day: '14'
doi: 10.1007/s11432-010-0068-y
extern: 1
intvolume: ' 53'
issue: '5'
month: '04'
page: 911 - 919
publication: 'Science in China, Series F: Information Sciences'
publication_status: published
publisher: Springer
publist_id: '4939'
quality_controlled: 0
status: public
title: Subsurface scattering using splat-based diffusion in point-based rendering
type: journal_article
volume: 53
year: '2010'
...