---
_id: '8470'
abstract:
- lang: eng
text: 'Adding a new dimension: 4D or 3D proton‐detected spectra of perdeuterated
protein samples with 1H labelled amides and methyl groups permit collecting unambiguous
distance restraints with high sensitivity and determining protein structure by
solid‐state NMR (see picture).'
article_processing_charge: No
article_type: original
author:
- first_name: Matthias
full_name: Huber, Matthias
last_name: Huber
- first_name: Sebastian
full_name: Hiller, Sebastian
last_name: Hiller
- first_name: Paul
full_name: Schanda, Paul
id: 7B541462-FAF6-11E9-A490-E8DFE5697425
last_name: Schanda
orcid: 0000-0002-9350-7606
- first_name: Matthias
full_name: Ernst, Matthias
last_name: Ernst
- first_name: Anja
full_name: Böckmann, Anja
last_name: Böckmann
- first_name: René
full_name: Verel, René
last_name: Verel
- first_name: Beat H.
full_name: Meier, Beat H.
last_name: Meier
citation:
ama: Huber M, Hiller S, Schanda P, et al. A proton-detected 4D solid-state NMR experiment
for protein structure determination. ChemPhysChem. 2011;12(5):915-918.
doi:10.1002/cphc.201100062
apa: Huber, M., Hiller, S., Schanda, P., Ernst, M., Böckmann, A., Verel, R., &
Meier, B. H. (2011). A proton-detected 4D solid-state NMR experiment for protein
structure determination. ChemPhysChem. Wiley. https://doi.org/10.1002/cphc.201100062
chicago: Huber, Matthias, Sebastian Hiller, Paul Schanda, Matthias Ernst, Anja Böckmann,
René Verel, and Beat H. Meier. “A Proton-Detected 4D Solid-State NMR Experiment
for Protein Structure Determination.” ChemPhysChem. Wiley, 2011. https://doi.org/10.1002/cphc.201100062.
ieee: M. Huber et al., “A proton-detected 4D solid-state NMR experiment for
protein structure determination,” ChemPhysChem, vol. 12, no. 5. Wiley,
pp. 915–918, 2011.
ista: Huber M, Hiller S, Schanda P, Ernst M, Böckmann A, Verel R, Meier BH. 2011.
A proton-detected 4D solid-state NMR experiment for protein structure determination.
ChemPhysChem. 12(5), 915–918.
mla: Huber, Matthias, et al. “A Proton-Detected 4D Solid-State NMR Experiment for
Protein Structure Determination.” ChemPhysChem, vol. 12, no. 5, Wiley,
2011, pp. 915–18, doi:10.1002/cphc.201100062.
short: M. Huber, S. Hiller, P. Schanda, M. Ernst, A. Böckmann, R. Verel, B.H. Meier,
ChemPhysChem 12 (2011) 915–918.
date_created: 2020-09-18T10:10:56Z
date_published: 2011-02-15T00:00:00Z
date_updated: 2021-01-12T08:19:30Z
day: '15'
doi: 10.1002/cphc.201100062
extern: '1'
intvolume: ' 12'
issue: '5'
keyword:
- Physical and Theoretical Chemistry
- Atomic and Molecular Physics
- and Optics
language:
- iso: eng
month: '02'
oa_version: None
page: 915-918
publication: ChemPhysChem
publication_identifier:
issn:
- 1439-4235
publication_status: published
publisher: Wiley
quality_controlled: '1'
status: public
title: A proton-detected 4D solid-state NMR experiment for protein structure determination
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 12
year: '2011'
...
---
_id: '8471'
abstract:
- lang: eng
text: Despite the importance of protein fibrils in the context of conformational
diseases, information on their structure is still sparse. Hydrogen/deuterium exchange
measurements of backbone amide protons allow the identification hydrogen-bonding
patterns and reveal pertinent information on the amyloid β-sheet architecture.
However, they provide only little information on the identity of residues exposed
to solvent or buried inside the fibril core. NMR spectroscopy is a potent method
for identifying solvent-accessible residues in proteins via observation of polarization
transfer between chemically exchanging side-chain protons and water protons. We
show here that the combined use of highly deuterated samples and fast magic-angle
spinning greatly attenuates unwanted spin diffusion and allows identification
of polarization exchange with the solvent in a site-specific manner. We apply
this measurement protocol to HET-s(218–289) prion fibrils under different conditions
(including physiological pH, where protofibrils assemble together into thicker
fibrils) and demonstrate that each protofibril of HET-s(218–289), is surrounded
by water, thus excluding the existence of extended dry interfibril contacts. We
also show that exchangeable side-chain protons inside the hydrophobic core of
HET-s(218–289) do not exchange over time intervals of weeks to months. The experiments
proposed in this study can provide insight into the detailed structural features
of amyloid fibrils in general.
article_processing_charge: No
article_type: original
author:
- first_name: Hélène
full_name: Van Melckebeke, Hélène
last_name: Van Melckebeke
- first_name: Paul
full_name: Schanda, Paul
id: 7B541462-FAF6-11E9-A490-E8DFE5697425
last_name: Schanda
orcid: 0000-0002-9350-7606
- first_name: Julia
full_name: Gath, Julia
last_name: Gath
- first_name: Christian
full_name: Wasmer, Christian
last_name: Wasmer
- first_name: René
full_name: Verel, René
last_name: Verel
- first_name: Adam
full_name: Lange, Adam
last_name: Lange
- first_name: Beat H.
full_name: Meier, Beat H.
last_name: Meier
- first_name: Anja
full_name: Böckmann, Anja
last_name: Böckmann
citation:
ama: Van Melckebeke H, Schanda P, Gath J, et al. Probing water accessibility in
HET-s(218–289) amyloid fibrils by solid-state NMR. Journal of Molecular Biology.
2011;405(3):765-772. doi:10.1016/j.jmb.2010.11.004
apa: Van Melckebeke, H., Schanda, P., Gath, J., Wasmer, C., Verel, R., Lange, A.,
… Böckmann, A. (2011). Probing water accessibility in HET-s(218–289) amyloid fibrils
by solid-state NMR. Journal of Molecular Biology. Elsevier. https://doi.org/10.1016/j.jmb.2010.11.004
chicago: Van Melckebeke, Hélène, Paul Schanda, Julia Gath, Christian Wasmer, René
Verel, Adam Lange, Beat H. Meier, and Anja Böckmann. “Probing Water Accessibility
in HET-s(218–289) Amyloid Fibrils by Solid-State NMR.” Journal of Molecular
Biology. Elsevier, 2011. https://doi.org/10.1016/j.jmb.2010.11.004.
ieee: H. Van Melckebeke et al., “Probing water accessibility in HET-s(218–289)
amyloid fibrils by solid-state NMR,” Journal of Molecular Biology, vol.
405, no. 3. Elsevier, pp. 765–772, 2011.
ista: Van Melckebeke H, Schanda P, Gath J, Wasmer C, Verel R, Lange A, Meier BH,
Böckmann A. 2011. Probing water accessibility in HET-s(218–289) amyloid fibrils
by solid-state NMR. Journal of Molecular Biology. 405(3), 765–772.
mla: Van Melckebeke, Hélène, et al. “Probing Water Accessibility in HET-s(218–289)
Amyloid Fibrils by Solid-State NMR.” Journal of Molecular Biology, vol.
405, no. 3, Elsevier, 2011, pp. 765–72, doi:10.1016/j.jmb.2010.11.004.
short: H. Van Melckebeke, P. Schanda, J. Gath, C. Wasmer, R. Verel, A. Lange, B.H.
Meier, A. Böckmann, Journal of Molecular Biology 405 (2011) 765–772.
date_created: 2020-09-18T10:11:03Z
date_published: 2011-01-21T00:00:00Z
date_updated: 2021-01-12T08:19:30Z
day: '21'
doi: 10.1016/j.jmb.2010.11.004
extern: '1'
intvolume: ' 405'
issue: '3'
language:
- iso: eng
month: '01'
oa_version: None
page: 765-772
publication: Journal of Molecular Biology
publication_identifier:
issn:
- 0022-2836
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: Probing water accessibility in HET-s(218–289) amyloid fibrils by solid-state
NMR
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 405
year: '2011'
...
---
_id: '8505'
abstract:
- lang: eng
text: The classical principle of least action says that orbits of mechanical systems
extremize action; an important subclass are those orbits that minimize action.
In this paper we utilize this principle along with Aubry-Mather theory to construct
(Birkhoff) regions of instability for a certain three-body problem, given by a
Hamiltonian system of 2 degrees of freedom. We believe that these methods can
be applied to construct instability regions for a variety of Hamiltonian systems
with 2 degrees of freedom. The Hamiltonian model we consider describes dynamics
of a Sun-Jupiter-comet system, and under some simplifying assumptions, we show
the existence of instabilities for the orbit of the comet. In particular, we show
that a comet which starts close to an orbit in the shape of an ellipse of eccentricity
e=0.66 can increase in eccentricity up to e=0.96. In the sequels to this paper,
we extend the result to beyond e=1 and show the existence of ejection orbits.
Such orbits are initially well within the range of our solar system. This might
give an indication of why most objects rotating around the Sun in our solar system
have relatively low eccentricity.
article_processing_charge: No
article_type: original
author:
- first_name: Joseph
full_name: Galante, Joseph
last_name: Galante
- first_name: Vadim
full_name: Kaloshin, Vadim
id: FE553552-CDE8-11E9-B324-C0EBE5697425
last_name: Kaloshin
orcid: 0000-0002-6051-2628
citation:
ama: Galante J, Kaloshin V. Destruction of invariant curves in the restricted circular
planar three-body problem by using comparison of action. Duke Mathematical
Journal. 2011;159(2):275-327. doi:10.1215/00127094-1415878
apa: Galante, J., & Kaloshin, V. (2011). Destruction of invariant curves in
the restricted circular planar three-body problem by using comparison of action.
Duke Mathematical Journal. Duke University Press. https://doi.org/10.1215/00127094-1415878
chicago: Galante, Joseph, and Vadim Kaloshin. “Destruction of Invariant Curves in
the Restricted Circular Planar Three-Body Problem by Using Comparison of Action.”
Duke Mathematical Journal. Duke University Press, 2011. https://doi.org/10.1215/00127094-1415878.
ieee: J. Galante and V. Kaloshin, “Destruction of invariant curves in the restricted
circular planar three-body problem by using comparison of action,” Duke Mathematical
Journal, vol. 159, no. 2. Duke University Press, pp. 275–327, 2011.
ista: Galante J, Kaloshin V. 2011. Destruction of invariant curves in the restricted
circular planar three-body problem by using comparison of action. Duke Mathematical
Journal. 159(2), 275–327.
mla: Galante, Joseph, and Vadim Kaloshin. “Destruction of Invariant Curves in the
Restricted Circular Planar Three-Body Problem by Using Comparison of Action.”
Duke Mathematical Journal, vol. 159, no. 2, Duke University Press, 2011,
pp. 275–327, doi:10.1215/00127094-1415878.
short: J. Galante, V. Kaloshin, Duke Mathematical Journal 159 (2011) 275–327.
date_created: 2020-09-18T10:47:41Z
date_published: 2011-08-04T00:00:00Z
date_updated: 2021-01-12T08:19:45Z
day: '04'
doi: 10.1215/00127094-1415878
extern: '1'
intvolume: ' 159'
issue: '2'
keyword:
- General Mathematics
language:
- iso: eng
month: '08'
oa_version: None
page: 275-327
publication: Duke Mathematical Journal
publication_identifier:
issn:
- 0012-7094
publication_status: published
publisher: Duke University Press
quality_controlled: '1'
status: public
title: Destruction of invariant curves in the restricted circular planar three-body
problem by using comparison of action
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 159
year: '2011'
...
---
_id: '881'
author:
- first_name: Fyodor
full_name: Fyodor Kondrashov
id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
last_name: Kondrashov
orcid: 0000-0001-8243-4694
citation:
ama: 'Kondrashov F. Gene Dosage and Duplication. In: Evolution after Gene Duplication.
Wiley-Blackwell; 2011:57-76. doi:10.1002/9780470619902.ch4'
apa: Kondrashov, F. (2011). Gene Dosage and Duplication. In Evolution after Gene
Duplication (pp. 57–76). Wiley-Blackwell. https://doi.org/10.1002/9780470619902.ch4
chicago: Kondrashov, Fyodor. “Gene Dosage and Duplication.” In Evolution after
Gene Duplication, 57–76. Wiley-Blackwell, 2011. https://doi.org/10.1002/9780470619902.ch4.
ieee: F. Kondrashov, “Gene Dosage and Duplication,” in Evolution after Gene Duplication,
Wiley-Blackwell, 2011, pp. 57–76.
ista: 'Kondrashov F. 2011.Gene Dosage and Duplication. In: Evolution after Gene
Duplication. , 57–76.'
mla: Kondrashov, Fyodor. “Gene Dosage and Duplication.” Evolution after Gene
Duplication, Wiley-Blackwell, 2011, pp. 57–76, doi:10.1002/9780470619902.ch4.
short: F. Kondrashov, in:, Evolution after Gene Duplication, Wiley-Blackwell, 2011,
pp. 57–76.
date_created: 2018-12-11T11:49:00Z
date_published: 2011-03-14T00:00:00Z
date_updated: 2021-01-12T08:21:08Z
day: '14'
doi: 10.1002/9780470619902.ch4
extern: 1
month: '03'
page: 57 - 76
publication: Evolution after Gene Duplication
publication_status: published
publisher: Wiley-Blackwell
publist_id: '6766'
quality_controlled: 0
status: public
title: Gene Dosage and Duplication
type: book_chapter
year: '2011'
...
---
_id: '890'
abstract:
- lang: eng
text: Recent discovery of the Large-billed Reed Warbler (Acrocephalus orinus) in
museums and in the wild significantly expanded our knowledge of its morphological
traits and genetic variability, and revealed new data on geographical distribution
of the breeding grounds, migration routes and wintering locations of this species.
It is now certain that A. orinus is breeding in Central Asia; however, the precise
area of distribution remains unclear. The difficulty in the further study of this
species lies in the small number of known specimens, with only 13 currently available
in museums, and in the relative uncertainty of the breeding area and habitat of
this species. Following morphological and genetic analyses from Svensson, et al,
we describe 14 new A. orinus specimens from collections of Zoological Museums
of the former USSR from the territory of Central Asian states. All of these specimens
were erroneously labeled as Blyth's Reed Warbler (A. dumetorum), which is thought
to be a breeding species in these areas. The 14 new A. orinus specimens were collected
during breeding season while most of the 85 A. dumetorum specimens from the same
area were collected during the migration period. Our data indicate that the Central
Asian territory previously attributed as breeding grounds of A. dumetorum is likely
to constitute the breeding territory of A. orinus. This rare case of a re-description
of the breeding territory of a lost species emphasizes the importance of maintenance
of museum collections around the world. If the present data on the breeding grounds
of A. orinus are confirmed with field observations and collections, the literature
on the biology of A. dumetorum from the southern part of its range may have to
be reconsidered.
acknowledgement: |
The work was supported by the Plan Nacional grant number BFU2009-09271 from the Spanish Ministry of Science and Innovation.
We extend our thanks to A.M. Peklo and I.V. Fadeev for granting us access to ornithological collections, to V.S. Shishkin, M.V. Kalyakin, R.D. Kashkarov, O.V. Belyalov and V.M. Loskot for valuable insights and to L. Svensson for extensive feedback on the manuscript. We thank E.I. Rogaev for access to ancient DNA facility.
author:
- first_name: Evgeniy
full_name: Koblik, Evgeniy A
last_name: Koblik
- first_name: Yaroslav
full_name: Red'Kin, Yaroslav A
last_name: Red'Kin
- first_name: Margarita
full_name: Meer, Margarita S
last_name: Meer
- first_name: Romain
full_name: Derelle, Romain
last_name: Derelle
- first_name: Sofia
full_name: Golenkina, Sofia A
last_name: Golenkina
- first_name: Fyodor
full_name: Fyodor Kondrashov
id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
last_name: Kondrashov
orcid: 0000-0001-8243-4694
- first_name: Vladimir
full_name: Arkhipov, Vladimir Y
last_name: Arkhipov
citation:
ama: 'Koblik E, Red’Kin Y, Meer M, et al. Acrocephalus orinus: A case of Mistaken
identity. PLoS One. 2011;6(4). doi:10.1371/journal.pone.0017716'
apa: 'Koblik, E., Red’Kin, Y., Meer, M., Derelle, R., Golenkina, S., Kondrashov,
F., & Arkhipov, V. (2011). Acrocephalus orinus: A case of Mistaken identity.
PLoS One. Public Library of Science. https://doi.org/10.1371/journal.pone.0017716'
chicago: 'Koblik, Evgeniy, Yaroslav Red’Kin, Margarita Meer, Romain Derelle, Sofia
Golenkina, Fyodor Kondrashov, and Vladimir Arkhipov. “Acrocephalus Orinus: A Case
of Mistaken Identity.” PLoS One. Public Library of Science, 2011. https://doi.org/10.1371/journal.pone.0017716.'
ieee: 'E. Koblik et al., “Acrocephalus orinus: A case of Mistaken identity,”
PLoS One, vol. 6, no. 4. Public Library of Science, 2011.'
ista: 'Koblik E, Red’Kin Y, Meer M, Derelle R, Golenkina S, Kondrashov F, Arkhipov
V. 2011. Acrocephalus orinus: A case of Mistaken identity. PLoS One. 6(4).'
mla: 'Koblik, Evgeniy, et al. “Acrocephalus Orinus: A Case of Mistaken Identity.”
PLoS One, vol. 6, no. 4, Public Library of Science, 2011, doi:10.1371/journal.pone.0017716.'
short: E. Koblik, Y. Red’Kin, M. Meer, R. Derelle, S. Golenkina, F. Kondrashov,
V. Arkhipov, PLoS One 6 (2011).
date_created: 2018-12-11T11:49:02Z
date_published: 2011-01-01T00:00:00Z
date_updated: 2021-01-12T08:21:18Z
day: '01'
doi: 10.1371/journal.pone.0017716
extern: 1
intvolume: ' 6'
issue: '4'
month: '01'
publication: PLoS One
publication_status: published
publisher: Public Library of Science
publist_id: '6760'
quality_controlled: 0
status: public
title: 'Acrocephalus orinus: A case of Mistaken identity'
type: journal_article
volume: 6
year: '2011'
...
---
_id: '90'
abstract:
- lang: eng
text: A popular method for generating micron-sized aerosols is to submerge ultrasonic
(ω ∼ MHz) piezoelectric oscillators in a water bath. The submerged oscillator
atomizes the fluid, creating droplets with radii proportional to the wavelength
of the standing wave at the fluid surface. Classical theory for the Faraday instability
predicts a parametric instability driving a capillary wave at the subharmonic
(ω / 2) frequency. For many applications it is desirable to reduce the size of
the droplets; however, using higher frequency oscillators becomes impractical
beyond a few MHz. Observations are presented that demonstrate that smaller droplets
may also be created by increasing the driving amplitude of the oscillator, and
that this effect becomes more pronounced for large driving frequencies. It is
shown that these observations are consistent with a transition from droplets associated
with subharmonic (ω/2) capillary waves to harmonic (ω) capillary waves induced
by larger driving frequencies and amplitudes, as predicted by a stability analysis
of the capillary waves.
author:
- first_name: Andrew P
full_name: Higginbotham, Andrew P
id: 4AD6785A-F248-11E8-B48F-1D18A9856A87
last_name: Higginbotham
orcid: 0000-0003-2607-2363
- first_name: A
full_name: Guillen, A
last_name: Guillen
- first_name: Nick
full_name: Jones, Nick
last_name: Jones
- first_name: Tom
full_name: Donnelly, Tom
last_name: Donnelly
- first_name: Andrew
full_name: Bernoff, Andrew
last_name: Bernoff
citation:
ama: Higginbotham AP, Guillen A, Jones N, Donnelly T, Bernoff A. Evidence of the
harmonic Faraday instability in ultrasonic atomization experiments with a deep,
inviscid fluid. Journal of the Acoustical Society of America. 2011;130(5):2694-2699.
doi:10.1121/1.3643816
apa: Higginbotham, A. P., Guillen, A., Jones, N., Donnelly, T., & Bernoff, A.
(2011). Evidence of the harmonic Faraday instability in ultrasonic atomization
experiments with a deep, inviscid fluid. Journal of the Acoustical Society
of America. Acoustical Society of America. https://doi.org/10.1121/1.3643816
chicago: Higginbotham, Andrew P, A Guillen, Nick Jones, Tom Donnelly, and Andrew
Bernoff. “Evidence of the Harmonic Faraday Instability in Ultrasonic Atomization
Experiments with a Deep, Inviscid Fluid.” Journal of the Acoustical Society
of America. Acoustical Society of America, 2011. https://doi.org/10.1121/1.3643816.
ieee: A. P. Higginbotham, A. Guillen, N. Jones, T. Donnelly, and A. Bernoff, “Evidence
of the harmonic Faraday instability in ultrasonic atomization experiments with
a deep, inviscid fluid,” Journal of the Acoustical Society of America,
vol. 130, no. 5. Acoustical Society of America, pp. 2694–2699, 2011.
ista: Higginbotham AP, Guillen A, Jones N, Donnelly T, Bernoff A. 2011. Evidence
of the harmonic Faraday instability in ultrasonic atomization experiments with
a deep, inviscid fluid. Journal of the Acoustical Society of America. 130(5),
2694–2699.
mla: Higginbotham, Andrew P., et al. “Evidence of the Harmonic Faraday Instability
in Ultrasonic Atomization Experiments with a Deep, Inviscid Fluid.” Journal
of the Acoustical Society of America, vol. 130, no. 5, Acoustical Society
of America, 2011, pp. 2694–99, doi:10.1121/1.3643816.
short: A.P. Higginbotham, A. Guillen, N. Jones, T. Donnelly, A. Bernoff, Journal
of the Acoustical Society of America 130 (2011) 2694–2699.
date_created: 2018-12-11T11:44:34Z
date_published: 2011-11-16T00:00:00Z
date_updated: 2021-01-12T08:21:44Z
day: '16'
doi: 10.1121/1.3643816
extern: '1'
external_id:
pmid:
- ' 22087897'
intvolume: ' 130'
issue: '5'
language:
- iso: eng
month: '11'
oa_version: None
page: 2694 - 2699
pmid: 1
publication: Journal of the Acoustical Society of America
publication_status: published
publisher: Acoustical Society of America
publist_id: '7964'
quality_controlled: '1'
status: public
title: Evidence of the harmonic Faraday instability in ultrasonic atomization experiments
with a deep, inviscid fluid
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 130
year: '2011'
...
---
_id: '1723'
abstract:
- lang: eng
text: The emergence of differences in the arrangement of cells is the first step
towards the establishment of many organs. Understanding this process is limited
by the lack of systematic characterization of epithelial organisation. Here we
apply network theory at the scale of individual cells to uncover patterns in cell-to-cell
contacts that govern epithelial organisation. We provide an objective characterisation
of epithelia using network representation, where cells are nodes and cell contacts
are links. The features of individual cells, together with attributes of the cellular
network, produce a defining signature that distinguishes epithelia from different
organs, species, developmental stages and genetic conditions. The approach permits
characterization, quantification and classification of normal and perturbed epithelia,
and establishes a framework for understanding molecular mechanisms that underpin
the architecture of complex tissues.
acknowledgement: We acknowledge the MRC for funding, M.M.B. acknowledges Darwin College,
EMBO YIP and Schlumberger Ltd for support. L.M.E. is funded by the Marie Curie and
the EMBO fellowships. L.d.F.C. is grateful to FAPESP (05/00587-5) and CNPq (301303/06-1)
for financial support. Part of this work was performed during a Visiting Scholarship
to L.d.F.C. from St Catharine's College, University of Cambridge. J.B. is supported
by the MRC (UK) and A.K. by a FEBS fellowship
author:
- first_name: Luis
full_name: Escudero, Luis M
last_name: Escudero
- first_name: Luciano
full_name: Costa, Luciano
last_name: Costa
- first_name: Anna
full_name: Anna Kicheva
id: 3959A2A0-F248-11E8-B48F-1D18A9856A87
last_name: Kicheva
orcid: 0000-0003-4509-4998
- first_name: James
full_name: Briscoe, James
last_name: Briscoe
- first_name: Matthew
full_name: Freeman, Matthew
last_name: Freeman
- first_name: Madan
full_name: Babu, Madan M
last_name: Babu
citation:
ama: Escudero L, Costa L, Kicheva A, Briscoe J, Freeman M, Babu M. Epithelial organisation
revealed by a network of cellular contacts. Nature Communications. 2011;2(1).
doi:10.1038/ncomms1536
apa: Escudero, L., Costa, L., Kicheva, A., Briscoe, J., Freeman, M., & Babu,
M. (2011). Epithelial organisation revealed by a network of cellular contacts.
Nature Communications. Nature Publishing Group. https://doi.org/10.1038/ncomms1536
chicago: Escudero, Luis, Luciano Costa, Anna Kicheva, James Briscoe, Matthew Freeman,
and Madan Babu. “Epithelial Organisation Revealed by a Network of Cellular Contacts.”
Nature Communications. Nature Publishing Group, 2011. https://doi.org/10.1038/ncomms1536.
ieee: L. Escudero, L. Costa, A. Kicheva, J. Briscoe, M. Freeman, and M. Babu, “Epithelial
organisation revealed by a network of cellular contacts,” Nature Communications,
vol. 2, no. 1. Nature Publishing Group, 2011.
ista: Escudero L, Costa L, Kicheva A, Briscoe J, Freeman M, Babu M. 2011. Epithelial
organisation revealed by a network of cellular contacts. Nature Communications.
2(1).
mla: Escudero, Luis, et al. “Epithelial Organisation Revealed by a Network of Cellular
Contacts.” Nature Communications, vol. 2, no. 1, Nature Publishing Group,
2011, doi:10.1038/ncomms1536.
short: L. Escudero, L. Costa, A. Kicheva, J. Briscoe, M. Freeman, M. Babu, Nature
Communications 2 (2011).
date_created: 2018-12-11T11:53:40Z
date_published: 2011-01-01T00:00:00Z
date_updated: 2021-01-12T06:52:46Z
day: '01'
doi: 10.1038/ncomms1536
extern: 1
intvolume: ' 2'
issue: '1'
month: '01'
publication: Nature Communications
publication_status: published
publisher: Nature Publishing Group
publist_id: '5405'
quality_controlled: 0
status: public
title: Epithelial organisation revealed by a network of cellular contacts
type: journal_article
volume: 2
year: '2011'
...
---
_id: '1724'
abstract:
- lang: eng
text: Morphogens, such as Decapentaplegic (Dpp) in the fly imaginal discs, form
graded concentration profiles that control patterning and growth of developing
organs. In the imaginal discs, proliferative growth is homogeneous in space, posing
the conundrum of how morphogen concentration gradients could control position-independent
growth. To understand the mechanism of proliferation control by the Dpp gradient,
we quantified Dpp concentration and signaling levels during wing disc growth.
Both Dpp concentration and signaling gradients scale with tissue size during development.
On average, cells divide when Dpp signaling levels have increased by 50%. Our
observations are consistent with a growth control mechanism based on temporal
changes of cellular morphogen signaling levels. For a scaling gradient, this mechanism
generates position-independent growth rates.
acknowledgement: P.M., T.B., and F.J. were supported by the Max-Planck-Gesellschaft.
O.W., A.K., C.S., and M.G.-G. were supported by Geneva University and by European
Research Council advanced investigator grant (SARA), SystemsX (LipidX), Swiss National
Science Foundation (SNF), National Centre of Competence in Research (NCCR) chemical
biology and Frontiers in Genetics and R'equip grants
author:
- first_name: Ortrud
full_name: Wartlick, Ortrud
last_name: Wartlick
- first_name: Peer
full_name: Mumcu, Peer
last_name: Mumcu
- first_name: Anna
full_name: Anna Kicheva
id: 3959A2A0-F248-11E8-B48F-1D18A9856A87
last_name: Kicheva
orcid: 0000-0003-4509-4998
- first_name: Thomas
full_name: Bittig, Thomas
last_name: Bittig
- first_name: Carole
full_name: Seum, Carole
last_name: Seum
- first_name: Frank
full_name: Jülicher, Frank
last_name: Jülicher
- first_name: Marcos
full_name: González-Gaitán, Marcos A
last_name: González Gaitán
citation:
ama: Wartlick O, Mumcu P, Kicheva A, et al. Dynamics of Dpp signaling and proliferation
control. Science. 2011;331(6021):1154-1159. doi:10.1126/science.1200037
apa: Wartlick, O., Mumcu, P., Kicheva, A., Bittig, T., Seum, C., Jülicher, F., &
González Gaitán, M. (2011). Dynamics of Dpp signaling and proliferation control.
Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.1200037
chicago: Wartlick, Ortrud, Peer Mumcu, Anna Kicheva, Thomas Bittig, Carole Seum,
Frank Jülicher, and Marcos González Gaitán. “Dynamics of Dpp Signaling and Proliferation
Control.” Science. American Association for the Advancement of Science,
2011. https://doi.org/10.1126/science.1200037.
ieee: O. Wartlick et al., “Dynamics of Dpp signaling and proliferation control,”
Science, vol. 331, no. 6021. American Association for the Advancement of
Science, pp. 1154–1159, 2011.
ista: Wartlick O, Mumcu P, Kicheva A, Bittig T, Seum C, Jülicher F, González Gaitán
M. 2011. Dynamics of Dpp signaling and proliferation control. Science. 331(6021),
1154–1159.
mla: Wartlick, Ortrud, et al. “Dynamics of Dpp Signaling and Proliferation Control.”
Science, vol. 331, no. 6021, American Association for the Advancement of
Science, 2011, pp. 1154–59, doi:10.1126/science.1200037.
short: O. Wartlick, P. Mumcu, A. Kicheva, T. Bittig, C. Seum, F. Jülicher, M. González
Gaitán, Science 331 (2011) 1154–1159.
date_created: 2018-12-11T11:53:40Z
date_published: 2011-03-04T00:00:00Z
date_updated: 2021-01-12T06:52:46Z
day: '04'
doi: 10.1126/science.1200037
extern: 1
intvolume: ' 331'
issue: '6021'
month: '03'
page: 1154 - 1159
publication: Science
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '5406'
quality_controlled: 0
status: public
title: Dynamics of Dpp signaling and proliferation control
type: journal_article
volume: 331
year: '2011'
...
---
_id: '1754'
abstract:
- lang: eng
text: 'We report on a technique enabling electrical control of the contact silicidation
process in silicon nanowire devices. Undoped silicon nanowires were contacted
by pairs of nickel electrodes and each contact was selectively silicided by means
of the Joule effect. By a realtime monitoring of the nanowire electrical resistance
during the contact silicidation process we were able to fabricate nickel-silicide/silicon/nickel-
silicide devices with controlled silicon channel length down to 8 nm. '
acknowledgement: This work was supported by the Agence Nationale de la Recherche (ANR)
through the ACCESS and COHESION projects and by the European Commission through
the Chemtronics program MEST-CT-2005-020513
arxiv: 1
author:
- first_name: Massimo
full_name: Mongillo, Massimo
last_name: Mongillo
- first_name: Panayotis
full_name: Spathis, Panayotis
last_name: Spathis
- first_name: Georgios
full_name: Katsaros, Georgios
id: 38DB5788-F248-11E8-B48F-1D18A9856A87
last_name: Katsaros
- first_name: Pascal
full_name: Gentile, Pascal
last_name: Gentile
- first_name: Marc
full_name: Sanquer, Marc
last_name: Sanquer
- first_name: Silvano
full_name: De Franceschi, Silvano
last_name: De Franceschi
citation:
ama: Mongillo M, Spathis P, Katsaros G, Gentile P, Sanquer M, De Franceschi S. Joule-assisted
silicidation for short-channel silicon nanowire devices. ACS Nano. 2011;5(9):7117-7123.
doi:10.1021/nn202524j
apa: Mongillo, M., Spathis, P., Katsaros, G., Gentile, P., Sanquer, M., & De
Franceschi, S. (2011). Joule-assisted silicidation for short-channel silicon nanowire
devices. ACS Nano. American Chemical Society. https://doi.org/10.1021/nn202524j
chicago: Mongillo, Massimo, Panayotis Spathis, Georgios Katsaros, Pascal Gentile,
Marc Sanquer, and Silvano De Franceschi. “Joule-Assisted Silicidation for Short-Channel
Silicon Nanowire Devices.” ACS Nano. American Chemical Society, 2011. https://doi.org/10.1021/nn202524j.
ieee: M. Mongillo, P. Spathis, G. Katsaros, P. Gentile, M. Sanquer, and S. De Franceschi,
“Joule-assisted silicidation for short-channel silicon nanowire devices,” ACS
Nano, vol. 5, no. 9. American Chemical Society, pp. 7117–7123, 2011.
ista: Mongillo M, Spathis P, Katsaros G, Gentile P, Sanquer M, De Franceschi S.
2011. Joule-assisted silicidation for short-channel silicon nanowire devices.
ACS Nano. 5(9), 7117–7123.
mla: Mongillo, Massimo, et al. “Joule-Assisted Silicidation for Short-Channel Silicon
Nanowire Devices.” ACS Nano, vol. 5, no. 9, American Chemical Society,
2011, pp. 7117–23, doi:10.1021/nn202524j.
short: M. Mongillo, P. Spathis, G. Katsaros, P. Gentile, M. Sanquer, S. De Franceschi,
ACS Nano 5 (2011) 7117–7123.
date_created: 2018-12-11T11:53:50Z
date_published: 2011-09-27T00:00:00Z
date_updated: 2021-01-12T06:52:59Z
day: '27'
doi: 10.1021/nn202524j
extern: '1'
external_id:
arxiv:
- '1110.5668'
intvolume: ' 5'
issue: '9'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1110.5668
month: '09'
oa: 1
oa_version: Preprint
page: 7117 - 7123
publication: ACS Nano
publication_status: published
publisher: American Chemical Society
publist_id: '5370'
quality_controlled: '1'
status: public
title: Joule-assisted silicidation for short-channel silicon nanowire devices
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2011'
...
---
_id: '1755'
abstract:
- lang: eng
text: Spin-selective tunneling of holes in SiGe nanocrystals contacted by normal-metal
leads is reported. The spin selectivity arises from an interplay of the orbital
effect of the magnetic field with the strong spin-orbit interaction present in
the valence band of the semiconductor. We demonstrate both experimentally and
theoretically that spin-selective tunneling in semiconductor nanostructures can
be achieved without the use of ferromagnetic contacts. The reported effect, which
relies on mixing the light and heavy holes, should be observable in a broad class
of quantum-dot systems formed in semiconductors with a degenerate valence band.
acknowledgement: The work was supported by the Agence Nationale de la Recherche (through
the ACCESS and COHESION projects), U.S. DOE Contract No. DE-FG02-08ER46482 (Yale),
and the Nanosciences Foundation at Grenoble, France. G. K. acknowledges support
from the Deutsche Forschungsgemeinschaft
author:
- first_name: Georgios
full_name: Georgios Katsaros
id: 38DB5788-F248-11E8-B48F-1D18A9856A87
last_name: Katsaros
- first_name: Vitaly
full_name: Golovach, Vitaly N
last_name: Golovach
- first_name: Panayotis
full_name: Spathis, Panayotis N
last_name: Spathis
- first_name: Natalia
full_name: Ares, Natalia
last_name: Ares
- first_name: Mathieu
full_name: Stoffel, Mathieu
last_name: Stoffel
- first_name: Frank
full_name: Fournel, Frank
last_name: Fournel
- first_name: Oliver
full_name: Schmidt, Oliver G
last_name: Schmidt
- first_name: Leonid
full_name: Glazman, Leonid I
last_name: Glazman
- first_name: Silvano
full_name: De Franceschi, Silvano
last_name: De Franceschi
citation:
ama: Katsaros G, Golovach V, Spathis P, et al. Observation of spin-selective tunneling
in sige nanocrystals. Physical Review Letters. 2011;107(24). doi:10.1103/PhysRevLett.107.246601
apa: Katsaros, G., Golovach, V., Spathis, P., Ares, N., Stoffel, M., Fournel, F.,
… De Franceschi, S. (2011). Observation of spin-selective tunneling in sige nanocrystals.
Physical Review Letters. American Physical Society. https://doi.org/10.1103/PhysRevLett.107.246601
chicago: Katsaros, Georgios, Vitaly Golovach, Panayotis Spathis, Natalia Ares, Mathieu
Stoffel, Frank Fournel, Oliver Schmidt, Leonid Glazman, and Silvano De Franceschi.
“Observation of Spin-Selective Tunneling in Sige Nanocrystals.” Physical Review
Letters. American Physical Society, 2011. https://doi.org/10.1103/PhysRevLett.107.246601.
ieee: G. Katsaros et al., “Observation of spin-selective tunneling in sige
nanocrystals,” Physical Review Letters, vol. 107, no. 24. American Physical
Society, 2011.
ista: Katsaros G, Golovach V, Spathis P, Ares N, Stoffel M, Fournel F, Schmidt O,
Glazman L, De Franceschi S. 2011. Observation of spin-selective tunneling in sige
nanocrystals. Physical Review Letters. 107(24).
mla: Katsaros, Georgios, et al. “Observation of Spin-Selective Tunneling in Sige
Nanocrystals.” Physical Review Letters, vol. 107, no. 24, American Physical
Society, 2011, doi:10.1103/PhysRevLett.107.246601.
short: G. Katsaros, V. Golovach, P. Spathis, N. Ares, M. Stoffel, F. Fournel, O.
Schmidt, L. Glazman, S. De Franceschi, Physical Review Letters 107 (2011).
date_created: 2018-12-11T11:53:50Z
date_published: 2011-12-07T00:00:00Z
date_updated: 2021-01-12T06:53:00Z
day: '07'
doi: 10.1103/PhysRevLett.107.246601
extern: 1
intvolume: ' 107'
issue: '24'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1107.3919
month: '12'
oa: 1
publication: Physical Review Letters
publication_status: published
publisher: American Physical Society
publist_id: '5369'
quality_controlled: 0
status: public
title: Observation of spin-selective tunneling in sige nanocrystals
type: journal_article
volume: 107
year: '2011'
...
---
_id: '1775'
abstract:
- lang: eng
text: At optical frequencies the radiation produced by a source, such as a laser,
a black body or a single-photon emitter, is frequently characterized by analysing
the temporal correlations of emitted photons using single-photon counters. At
microwave frequencies, however, there are no efficient single-photon counters
yet. Instead, well-developed linear amplifiers allow for efficient measurement
of the amplitude of an electromagnetic field. Here, we demonstrate first- and
second-order correlation function measurements of a pulsed microwave-frequency
single-photon source integrated on the same chip with a 50/50 beam splitter followed
by linear amplifiers and quadrature amplitude detectors. We clearly observe single-photon
coherence in first-order and photon antibunching in second-order correlation function
measurements of the propagating fields.
acknowledgement: This work was supported by the European Research Council (ERC) through
a Starting Grant and by ETHZ. M.P.d.S. was supported by a NSERC postdoctoral fellowship.
A.B. was supported by NSERC, CIFAR and the Alfred P. Sloan Foundation
author:
- first_name: Deniz
full_name: Bozyigit, Deniz
last_name: Bozyigit
- first_name: C
full_name: Lang, C
last_name: Lang
- first_name: L.
full_name: Steffen, L. Kraig
last_name: Steffen
- first_name: Johannes M
full_name: Johannes Fink
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
- first_name: Christopher
full_name: Eichler, Christopher
last_name: Eichler
- first_name: Matthias
full_name: Baur, Matthias P
last_name: Baur
- first_name: R
full_name: Bianchetti, R
last_name: Bianchetti
- first_name: Peter
full_name: Leek, Peter J
last_name: Leek
- first_name: Stefan
full_name: Filipp, Stefan
last_name: Filipp
- first_name: Marcus
full_name: Da Silva, Marcus P
last_name: Da Silva
- first_name: Alexandre
full_name: Blais, Alexandre
last_name: Blais
- first_name: Andreas
full_name: Wallraff, Andreas
last_name: Wallraff
citation:
ama: Bozyigit D, Lang C, Steffen L, et al. Antibunching of microwave-frequency photons
observed in correlation measurements using linear detectors. Nature Physics.
2011;7(2):154-158. doi:10.1038/nphys1845
apa: Bozyigit, D., Lang, C., Steffen, L., Fink, J. M., Eichler, C., Baur, M., …
Wallraff, A. (2011). Antibunching of microwave-frequency photons observed in correlation
measurements using linear detectors. Nature Physics. Nature Publishing
Group. https://doi.org/10.1038/nphys1845
chicago: Bozyigit, Deniz, C Lang, L. Steffen, Johannes M Fink, Christopher Eichler,
Matthias Baur, R Bianchetti, et al. “Antibunching of Microwave-Frequency Photons
Observed in Correlation Measurements Using Linear Detectors.” Nature Physics.
Nature Publishing Group, 2011. https://doi.org/10.1038/nphys1845.
ieee: D. Bozyigit et al., “Antibunching of microwave-frequency photons observed
in correlation measurements using linear detectors,” Nature Physics, vol.
7, no. 2. Nature Publishing Group, pp. 154–158, 2011.
ista: Bozyigit D, Lang C, Steffen L, Fink JM, Eichler C, Baur M, Bianchetti R, Leek
P, Filipp S, Da Silva M, Blais A, Wallraff A. 2011. Antibunching of microwave-frequency
photons observed in correlation measurements using linear detectors. Nature Physics.
7(2), 154–158.
mla: Bozyigit, Deniz, et al. “Antibunching of Microwave-Frequency Photons Observed
in Correlation Measurements Using Linear Detectors.” Nature Physics, vol.
7, no. 2, Nature Publishing Group, 2011, pp. 154–58, doi:10.1038/nphys1845.
short: D. Bozyigit, C. Lang, L. Steffen, J.M. Fink, C. Eichler, M. Baur, R. Bianchetti,
P. Leek, S. Filipp, M. Da Silva, A. Blais, A. Wallraff, Nature Physics 7 (2011)
154–158.
date_created: 2018-12-11T11:53:57Z
date_published: 2011-02-01T00:00:00Z
date_updated: 2021-01-12T06:53:07Z
day: '01'
doi: 10.1038/nphys1845
extern: 1
intvolume: ' 7'
issue: '2'
month: '02'
page: 154 - 158
publication: Nature Physics
publication_status: published
publisher: Nature Publishing Group
publist_id: '5340'
quality_controlled: 0
status: public
title: Antibunching of microwave-frequency photons observed in correlation measurements
using linear detectors
type: journal_article
volume: 7
year: '2011'
...
---
_id: '1776'
abstract:
- lang: eng
text: Superconducting circuits have been successfully established as systems to
prepare and investigate microwave light fields at the quantum level. In contrast
to optical experiments where light is detected using photon counters, microwaves
are usually measured with well developed linear amplifiers. This makes measurements
of correlation functions - one of the important tools in optics - harder to achieve
because they traditionally rely on photon counters and beam splitters. Here, we
demonstrate a system where we can prepare on demand single microwave photons in
a cavity and detect them at the two outputs of the cavity using linear amplifiers.
Together with efficient data processing, this allows us to measure different observables
of the cavity photons, including the first-order correlation function. Using these
techniques we demonstrate cooling of a thermal background field in the cavity.
acknowledgement: Australian National University,Aust. Res. Counc. Cent. Excellence
Quantum-Atom Opt.,Griffith University,Ian Potter Foundation,International Union
of Pure and Applied Physics
alternative_title:
- 'Journal of Physics: Conference Series'
author:
- first_name: Deniz
full_name: Bozyigit, Deniz
last_name: Bozyigit
- first_name: C
full_name: Lang, C
last_name: Lang
- first_name: L.
full_name: Steffen, L. Kraig
last_name: Steffen
- first_name: Johannes M
full_name: Johannes Fink
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
- first_name: Christopher
full_name: Eichler, Christopher
last_name: Eichler
- first_name: Matthias
full_name: Baur, Matthias P
last_name: Baur
- first_name: R
full_name: Bianchetti, R
last_name: Bianchetti
- first_name: Peter
full_name: Leek, Peter J
last_name: Leek
- first_name: Stefan
full_name: Filipp, Stefan
last_name: Filipp
- first_name: Andreas
full_name: Wallraff, Andreas
last_name: Wallraff
- first_name: Marcus
full_name: Da Silva, Marcus P
last_name: Da Silva
- first_name: Alexandre
full_name: Blais, Alexandre
last_name: Blais
citation:
ama: 'Bozyigit D, Lang C, Steffen L, et al. Correlation measurements of individual
microwave photons emitted from a symmetric cavity. In: Vol 264. IOP Publishing
Ltd.; 2011. doi:10.1088/1742-6596/264/1/012024'
apa: Bozyigit, D., Lang, C., Steffen, L., Fink, J. M., Eichler, C., Baur, M., …
Blais, A. (2011). Correlation measurements of individual microwave photons emitted
from a symmetric cavity (Vol. 264). Presented at the International Conference
on Atomic Physics, IOP Publishing Ltd. https://doi.org/10.1088/1742-6596/264/1/012024
chicago: Bozyigit, Deniz, C Lang, L. Steffen, Johannes M Fink, Christopher Eichler,
Matthias Baur, R Bianchetti, et al. “Correlation Measurements of Individual Microwave
Photons Emitted from a Symmetric Cavity,” Vol. 264. IOP Publishing Ltd., 2011.
https://doi.org/10.1088/1742-6596/264/1/012024.
ieee: D. Bozyigit et al., “Correlation measurements of individual microwave
photons emitted from a symmetric cavity,” presented at the International Conference
on Atomic Physics, 2011, vol. 264, no. 1.
ista: 'Bozyigit D, Lang C, Steffen L, Fink JM, Eichler C, Baur M, Bianchetti R,
Leek P, Filipp S, Wallraff A, Da Silva M, Blais A. 2011. Correlation measurements
of individual microwave photons emitted from a symmetric cavity. International
Conference on Atomic Physics, Journal of Physics: Conference Series, vol. 264.'
mla: Bozyigit, Deniz, et al. Correlation Measurements of Individual Microwave
Photons Emitted from a Symmetric Cavity. Vol. 264, no. 1, IOP Publishing Ltd.,
2011, doi:10.1088/1742-6596/264/1/012024.
short: D. Bozyigit, C. Lang, L. Steffen, J.M. Fink, C. Eichler, M. Baur, R. Bianchetti,
P. Leek, S. Filipp, A. Wallraff, M. Da Silva, A. Blais, in:, IOP Publishing Ltd.,
2011.
conference:
name: International Conference on Atomic Physics
date_created: 2018-12-11T11:53:57Z
date_published: 2011-01-01T00:00:00Z
date_updated: 2019-04-26T07:22:05Z
day: '01'
doi: 10.1088/1742-6596/264/1/012024
extern: 1
intvolume: ' 264'
issue: '1'
month: '01'
publication_status: published
publisher: IOP Publishing Ltd.
publist_id: '5339'
quality_controlled: 0
status: public
title: Correlation measurements of individual microwave photons emitted from a symmetric
cavity
type: conference
volume: 264
year: '2011'
...
---
_id: '1777'
abstract:
- lang: eng
text: A wide range of experiments studying microwave photons localized in superconducting
cavities have made important contributions to our understanding of the quantum
properties of radiation. Propagating microwave photons, however, have so far been
studied much less intensely. Here we present measurements in which we reconstruct
the quantum state of itinerant single photon Fock states and their superposition
with the vacuum by analyzing moments of the measured amplitude distribution up
to fourth order. Using linear amplifiers and quadrature amplitude detectors, we
have developed efficient methods to separate the detected single photon signal
from the noise added by the amplifier. From our measurement data we have also
reconstructed the corresponding Wigner function.
acknowledgement: This work was supported by the European Research Council (ERC) through
a Starting Grant and by ETHZ
article_processing_charge: No
author:
- first_name: Christopher
full_name: Eichler, Christopher
last_name: Eichler
- first_name: Deniz
full_name: Bozyigit, Deniz
last_name: Bozyigit
- first_name: C
full_name: Lang, C
last_name: Lang
- first_name: L.
full_name: Steffen, L.
last_name: Steffen
- first_name: Johannes M
full_name: Fink, Johannes M
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
- first_name: Andreas
full_name: Wallraff, Andreas
last_name: Wallraff
citation:
ama: Eichler C, Bozyigit D, Lang C, Steffen L, Fink JM, Wallraff A. Experimental
state tomography of itinerant single microwave photons. Physical Review Letters.
2011;106(22). doi:10.1103/PhysRevLett.106.220503
apa: Eichler, C., Bozyigit, D., Lang, C., Steffen, L., Fink, J. M., & Wallraff,
A. (2011). Experimental state tomography of itinerant single microwave photons.
Physical Review Letters. American Physical Society. https://doi.org/10.1103/PhysRevLett.106.220503
chicago: Eichler, Christopher, Deniz Bozyigit, C Lang, L. Steffen, Johannes M Fink,
and Andreas Wallraff. “Experimental State Tomography of Itinerant Single Microwave
Photons.” Physical Review Letters. American Physical Society, 2011. https://doi.org/10.1103/PhysRevLett.106.220503.
ieee: C. Eichler, D. Bozyigit, C. Lang, L. Steffen, J. M. Fink, and A. Wallraff,
“Experimental state tomography of itinerant single microwave photons,” Physical
Review Letters, vol. 106, no. 22. American Physical Society, 2011.
ista: Eichler C, Bozyigit D, Lang C, Steffen L, Fink JM, Wallraff A. 2011. Experimental
state tomography of itinerant single microwave photons. Physical Review Letters.
106(22).
mla: Eichler, Christopher, et al. “Experimental State Tomography of Itinerant Single
Microwave Photons.” Physical Review Letters, vol. 106, no. 22, American
Physical Society, 2011, doi:10.1103/PhysRevLett.106.220503.
short: C. Eichler, D. Bozyigit, C. Lang, L. Steffen, J.M. Fink, A. Wallraff, Physical
Review Letters 106 (2011).
date_created: 2018-12-11T11:53:57Z
date_published: 2011-06-01T00:00:00Z
date_updated: 2021-11-16T07:57:13Z
day: '01'
doi: 10.1103/PhysRevLett.106.220503
extern: '1'
intvolume: ' 106'
issue: '22'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1011.6668
month: '06'
oa: 1
oa_version: None
publication: Physical Review Letters
publication_status: published
publisher: American Physical Society
publist_id: '5338'
related_material:
link:
- relation: erratum
url: https://doi.org/10.1103/PhysRevLett.106.249901
status: public
title: Experimental state tomography of itinerant single microwave photons
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 106
year: '2011'
...
---
_id: '1778'
abstract:
- lang: eng
text: Creating a train of single photons and monitoring its propagation and interaction
is challenging in most physical systems, as photons generally interact very weakly
with other systems. However, when confining microwave frequency photons in a transmission
line resonator, effective photon-photon interactions can be mediated by qubits
embedded in the resonator. Here, we observe the phenomenon of photon blockade
through second-order correlation function measurements. The experiments clearly
demonstrate antibunching in a continuously pumped source of single microwave photons
measured by using microwave beam splitters, linear amplifiers, and quadrature
amplitude detectors. We also investigate resonance fluorescence and Rayleigh scattering
in Mollow-triplet-like spectra.
acknowledgement: This work was supported by the European Research Council (ERC) through
a Starting Grant and by ETHZ. M. P. d. S. was supported by NSERC. A. B. was supported
by NSERC, CIFAR, and the Alfred P. Sloan Foundation
author:
- first_name: C
full_name: Lang, C
last_name: Lang
- first_name: Deniz
full_name: Bozyigit, Deniz
last_name: Bozyigit
- first_name: Christopher
full_name: Eichler, Christopher
last_name: Eichler
- first_name: L.
full_name: Steffen, L. Kraig
last_name: Steffen
- first_name: Johannes M
full_name: Johannes Fink
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
- first_name: Abdufarrukh
full_name: Abdumalikov, Abdufarrukh A
last_name: Abdumalikov
- first_name: Matthias
full_name: Baur, Matthias P
last_name: Baur
- first_name: Stefan
full_name: Filipp, Stefan
last_name: Filipp
- first_name: Marcus
full_name: Da Silva, Marcus P
last_name: Da Silva
- first_name: Alexandre
full_name: Blais, Alexandre
last_name: Blais
- first_name: Andreas
full_name: Wallraff, Andreas
last_name: Wallraff
citation:
ama: Lang C, Bozyigit D, Eichler C, et al. Observation of resonant photon blockade
at microwave frequencies using correlation function measurements. Physical
Review Letters. 2011;106(24). doi:10.1103/PhysRevLett.106.243601
apa: Lang, C., Bozyigit, D., Eichler, C., Steffen, L., Fink, J. M., Abdumalikov,
A., … Wallraff, A. (2011). Observation of resonant photon blockade at microwave
frequencies using correlation function measurements. Physical Review Letters.
American Physical Society. https://doi.org/10.1103/PhysRevLett.106.243601
chicago: Lang, C, Deniz Bozyigit, Christopher Eichler, L. Steffen, Johannes M Fink,
Abdufarrukh Abdumalikov, Matthias Baur, et al. “Observation of Resonant Photon
Blockade at Microwave Frequencies Using Correlation Function Measurements.” Physical
Review Letters. American Physical Society, 2011. https://doi.org/10.1103/PhysRevLett.106.243601.
ieee: C. Lang et al., “Observation of resonant photon blockade at microwave
frequencies using correlation function measurements,” Physical Review Letters,
vol. 106, no. 24. American Physical Society, 2011.
ista: Lang C, Bozyigit D, Eichler C, Steffen L, Fink JM, Abdumalikov A, Baur M,
Filipp S, Da Silva M, Blais A, Wallraff A. 2011. Observation of resonant photon
blockade at microwave frequencies using correlation function measurements. Physical
Review Letters. 106(24).
mla: Lang, C., et al. “Observation of Resonant Photon Blockade at Microwave Frequencies
Using Correlation Function Measurements.” Physical Review Letters, vol.
106, no. 24, American Physical Society, 2011, doi:10.1103/PhysRevLett.106.243601.
short: C. Lang, D. Bozyigit, C. Eichler, L. Steffen, J.M. Fink, A. Abdumalikov,
M. Baur, S. Filipp, M. Da Silva, A. Blais, A. Wallraff, Physical Review Letters
106 (2011).
date_created: 2018-12-11T11:53:57Z
date_published: 2011-06-15T00:00:00Z
date_updated: 2021-01-12T06:53:08Z
day: '15'
doi: 10.1103/PhysRevLett.106.243601
extern: 1
intvolume: ' 106'
issue: '24'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1102.0461
month: '06'
oa: 1
publication: Physical Review Letters
publication_status: published
publisher: American Physical Society
publist_id: '5336'
quality_controlled: 0
status: public
title: Observation of resonant photon blockade at microwave frequencies using correlation
function measurements
type: journal_article
volume: 106
year: '2011'
...
---
_id: '1780'
abstract:
- lang: eng
text: Continuous variable entanglement between two modes of a radiation field is
usually studied at optical frequencies. Here we demonstrate experiments that show
the entanglement between microwave photons of different energy in a broadband
squeezed beam. We use a Josephson parametric amplifier to generate the two-mode
correlated state and detect all four quadrature components simultaneously in a
two-channel heterodyne setup using amplitude detectors. Analyzing two-dimensional
phase space histograms for all possible pairs of quadratures allows us to determine
the full covariance matrix, which is in good agreement with the one expected for
a two-mode squeezed state.
acknowledgement: This work was supported by the European Research Council (ERC) through
a Starting grant and by ETHZ. S. F. acknowledges the Austrian Science Foundation
(FWF) for support
author:
- first_name: Christopher
full_name: Eichler, Christopher
last_name: Eichler
- first_name: Deniz
full_name: Bozyigit, Deniz
last_name: Bozyigit
- first_name: C
full_name: Lang, C
last_name: Lang
- first_name: Matthias
full_name: Baur, Matthias P
last_name: Baur
- first_name: L.
full_name: Steffen, L. Kraig
last_name: Steffen
- first_name: Johannes M
full_name: Johannes Fink
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
- first_name: Stefan
full_name: Filipp, Stefan
last_name: Filipp
- first_name: Andreas
full_name: Wallraff, Andreas
last_name: Wallraff
citation:
ama: Eichler C, Bozyigit D, Lang C, et al. Observation of two-mode squeezing in
the microwave frequency domain. Physical Review Letters. 2011;107(11).
doi:10.1103/PhysRevLett.107.113601
apa: Eichler, C., Bozyigit, D., Lang, C., Baur, M., Steffen, L., Fink, J. M., …
Wallraff, A. (2011). Observation of two-mode squeezing in the microwave frequency
domain. Physical Review Letters. American Physical Society. https://doi.org/10.1103/PhysRevLett.107.113601
chicago: Eichler, Christopher, Deniz Bozyigit, C Lang, Matthias Baur, L. Steffen,
Johannes M Fink, Stefan Filipp, and Andreas Wallraff. “Observation of Two-Mode
Squeezing in the Microwave Frequency Domain.” Physical Review Letters.
American Physical Society, 2011. https://doi.org/10.1103/PhysRevLett.107.113601.
ieee: C. Eichler et al., “Observation of two-mode squeezing in the microwave
frequency domain,” Physical Review Letters, vol. 107, no. 11. American
Physical Society, 2011.
ista: Eichler C, Bozyigit D, Lang C, Baur M, Steffen L, Fink JM, Filipp S, Wallraff
A. 2011. Observation of two-mode squeezing in the microwave frequency domain.
Physical Review Letters. 107(11).
mla: Eichler, Christopher, et al. “Observation of Two-Mode Squeezing in the Microwave
Frequency Domain.” Physical Review Letters, vol. 107, no. 11, American
Physical Society, 2011, doi:10.1103/PhysRevLett.107.113601.
short: C. Eichler, D. Bozyigit, C. Lang, M. Baur, L. Steffen, J.M. Fink, S. Filipp,
A. Wallraff, Physical Review Letters 107 (2011).
date_created: 2018-12-11T11:53:58Z
date_published: 2011-09-06T00:00:00Z
date_updated: 2021-01-12T06:53:09Z
day: '06'
doi: 10.1103/PhysRevLett.107.113601
extern: 1
intvolume: ' 107'
issue: '11'
month: '09'
publication: Physical Review Letters
publication_status: published
publisher: American Physical Society
publist_id: '5334'
quality_controlled: 0
status: public
title: Observation of two-mode squeezing in the microwave frequency domain
type: journal_article
volume: 107
year: '2011'
...
---
_id: '1781'
abstract:
- lang: eng
text: Microwave cavities with high quality factors enable coherent coupling of distant
quantum systems. Virtual photons lead to a transverse interaction between qubits
when they are nonresonant with the cavity but resonant with each other. We experimentally
investigate the inverse scaling of the interqubit coupling with the detuning from
a cavity mode and its proportionality to the qubit-cavity interaction strength.
We demonstrate that the enhanced coupling at higher frequencies is mediated by
multiple higher-harmonic cavity modes. Moreover, we observe dark states of the
coupled qubit-qubit system and analyze their relation to the symmetry of the applied
driving field at different frequencies.
acknowledgement: This work was supported by the Swiss National Science Foundation
(SNF), the Austrian Science Foundation (FWF), and ETH Zurich
author:
- first_name: Stefan
full_name: Filipp, Stefan
last_name: Filipp
- first_name: M
full_name: Göppl, M
last_name: Göppl
- first_name: Johannes M
full_name: Johannes Fink
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
- first_name: Matthias
full_name: Baur, Matthias P
last_name: Baur
- first_name: R
full_name: Bianchetti, R
last_name: Bianchetti
- first_name: L.
full_name: Steffen, L. Kraig
last_name: Steffen
- first_name: Andreas
full_name: Wallraff, Andreas
last_name: Wallraff
citation:
ama: Filipp S, Göppl M, Fink JM, et al. Multimode mediated qubit-qubit coupling
and dark-state symmetries in circuit quantum electrodynamics. Physical Review
A - Atomic, Molecular, and Optical Physics. 2011;83(6). doi:10.1103/PhysRevA.83.063827
apa: Filipp, S., Göppl, M., Fink, J. M., Baur, M., Bianchetti, R., Steffen, L.,
& Wallraff, A. (2011). Multimode mediated qubit-qubit coupling and dark-state
symmetries in circuit quantum electrodynamics. Physical Review A - Atomic,
Molecular, and Optical Physics. American Physical Society. https://doi.org/10.1103/PhysRevA.83.063827
chicago: Filipp, Stefan, M Göppl, Johannes M Fink, Matthias Baur, R Bianchetti,
L. Steffen, and Andreas Wallraff. “Multimode Mediated Qubit-Qubit Coupling and
Dark-State Symmetries in Circuit Quantum Electrodynamics.” Physical Review
A - Atomic, Molecular, and Optical Physics. American Physical Society, 2011.
https://doi.org/10.1103/PhysRevA.83.063827.
ieee: S. Filipp et al., “Multimode mediated qubit-qubit coupling and dark-state
symmetries in circuit quantum electrodynamics,” Physical Review A - Atomic,
Molecular, and Optical Physics, vol. 83, no. 6. American Physical Society,
2011.
ista: Filipp S, Göppl M, Fink JM, Baur M, Bianchetti R, Steffen L, Wallraff A. 2011.
Multimode mediated qubit-qubit coupling and dark-state symmetries in circuit quantum
electrodynamics. Physical Review A - Atomic, Molecular, and Optical Physics. 83(6).
mla: Filipp, Stefan, et al. “Multimode Mediated Qubit-Qubit Coupling and Dark-State
Symmetries in Circuit Quantum Electrodynamics.” Physical Review A - Atomic,
Molecular, and Optical Physics, vol. 83, no. 6, American Physical Society,
2011, doi:10.1103/PhysRevA.83.063827.
short: S. Filipp, M. Göppl, J.M. Fink, M. Baur, R. Bianchetti, L. Steffen, A. Wallraff,
Physical Review A - Atomic, Molecular, and Optical Physics 83 (2011).
date_created: 2018-12-11T11:53:58Z
date_published: 2011-06-22T00:00:00Z
date_updated: 2021-01-12T06:53:09Z
day: '22'
doi: 10.1103/PhysRevA.83.063827
extern: 1
intvolume: ' 83'
issue: '6'
month: '06'
publication: Physical Review A - Atomic, Molecular, and Optical Physics
publication_status: published
publisher: American Physical Society
publist_id: '5335'
quality_controlled: 0
status: public
title: Multimode mediated qubit-qubit coupling and dark-state symmetries in circuit
quantum electrodynamics
type: journal_article
volume: 83
year: '2011'
...
---
_id: '1815'
abstract:
- lang: eng
text: Many membrane channels and receptors exhibit adaptive, or desensitized, response
to a strong sustained input stimulus, often supported by protein activity-dependent
inactivation. Adaptive response is thought to be related to various cellular functions
such as homeostasis and enlargement of dynamic range by background compensation.
Here we study the quantitative relation between adaptive response and background
compensation within a modeling framework. We show that any particular type of
adaptive response is neither sufficient nor necessary for adaptive enlargement
of dynamic range. In particular a precise adaptive response, where system activity
is maintained at a constant level at steady state, does not ensure a large dynamic
range neither in input signal nor in system output. A general mechanism for input
dynamic range enlargement can come about from the activity-dependent modulation
of protein responsiveness by multiple biochemical modification, regardless of
the type of adaptive response it induces. Therefore hierarchical biochemical processes
such as methylation and phosphorylation are natural candidates to induce this
property in signaling systems.
author:
- first_name: Tamar
full_name: Tamar Friedlander
id: 36A5845C-F248-11E8-B48F-1D18A9856A87
last_name: Friedlander
- first_name: Naama
full_name: Brenner, Naama
last_name: Brenner
citation:
ama: Friedlander T, Brenner N. Adaptive response and enlargement of dynamic range.
Mathematical Biosciences and Engineering. 2011;8(2):515-526. doi:10.3934/mbe.2011.8.515
apa: Friedlander, T., & Brenner, N. (2011). Adaptive response and enlargement
of dynamic range. Mathematical Biosciences and Engineering. Arizona State
University. https://doi.org/10.3934/mbe.2011.8.515
chicago: Friedlander, Tamar, and Naama Brenner. “Adaptive Response and Enlargement
of Dynamic Range.” Mathematical Biosciences and Engineering. Arizona State
University, 2011. https://doi.org/10.3934/mbe.2011.8.515.
ieee: T. Friedlander and N. Brenner, “Adaptive response and enlargement of dynamic
range,” Mathematical Biosciences and Engineering, vol. 8, no. 2. Arizona
State University, pp. 515–526, 2011.
ista: Friedlander T, Brenner N. 2011. Adaptive response and enlargement of dynamic
range. Mathematical Biosciences and Engineering. 8(2), 515–526.
mla: Friedlander, Tamar, and Naama Brenner. “Adaptive Response and Enlargement of
Dynamic Range.” Mathematical Biosciences and Engineering, vol. 8, no. 2,
Arizona State University, 2011, pp. 515–26, doi:10.3934/mbe.2011.8.515.
short: T. Friedlander, N. Brenner, Mathematical Biosciences and Engineering 8 (2011)
515–526.
date_created: 2018-12-11T11:54:10Z
date_published: 2011-04-02T00:00:00Z
date_updated: 2021-01-12T06:53:23Z
day: '02'
doi: 10.3934/mbe.2011.8.515
extern: 1
intvolume: ' 8'
issue: '2'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1003.2791
month: '04'
oa: 1
page: 515 - 526
publication: Mathematical Biosciences and Engineering
publication_status: published
publisher: Arizona State University
publist_id: '5291'
quality_controlled: 0
status: public
title: Adaptive response and enlargement of dynamic range
type: journal_article
volume: 8
year: '2011'
...
---
_id: '1863'
abstract:
- lang: eng
text: The Levene model is the simplest mathematical model to describe the evolution
of gene frequencies in spatially subdivided populations. It provides insight into
how locally varying selection promotes a population’s genetic diversity. Despite
its simplicity, interesting problems have remained unsolved even in the diallelic
case. In this paper we answer an open problem by establishing that for two alleles
at one locus and J demes, up to 2J−1 polymorphic equilibria may coexist. We first
present a proof for the case of stable monomorphisms and then show that the result
also holds for protected alleles. These findings allow us to prove that any odd
number (up to 2J−1) of equilibria is possible, before we extend the proof to even
numbers. We conclude with some numerical results and show that for J>2, the
proportion of parameter space affording this maximum is extremely small.
acknowledgement: FWF 21305
author:
- first_name: Sebastian
full_name: Sebastian Novak
id: 461468AE-F248-11E8-B48F-1D18A9856A87
last_name: Novak
citation:
ama: Novak S. The number of equilibria in the diallelic Levene model with multiple
demes. Theoretical Population Biology. 2011;79(3):97-101. doi:10.1016/j.tpb.2010.12.002
apa: Novak, S. (2011). The number of equilibria in the diallelic Levene model with
multiple demes. Theoretical Population Biology. Academic Press. https://doi.org/10.1016/j.tpb.2010.12.002
chicago: Novak, Sebastian. “The Number of Equilibria in the Diallelic Levene Model
with Multiple Demes.” Theoretical Population Biology. Academic Press, 2011.
https://doi.org/10.1016/j.tpb.2010.12.002.
ieee: S. Novak, “The number of equilibria in the diallelic Levene model with multiple
demes,” Theoretical Population Biology, vol. 79, no. 3. Academic Press,
pp. 97–101, 2011.
ista: Novak S. 2011. The number of equilibria in the diallelic Levene model with
multiple demes. Theoretical Population Biology. 79(3), 97–101.
mla: Novak, Sebastian. “The Number of Equilibria in the Diallelic Levene Model with
Multiple Demes.” Theoretical Population Biology, vol. 79, no. 3, Academic
Press, 2011, pp. 97–101, doi:10.1016/j.tpb.2010.12.002.
short: S. Novak, Theoretical Population Biology 79 (2011) 97–101.
date_created: 2018-12-11T11:54:25Z
date_published: 2011-05-01T00:00:00Z
date_updated: 2021-01-12T06:53:42Z
day: '01'
doi: 10.1016/j.tpb.2010.12.002
extern: 1
intvolume: ' 79'
issue: '3'
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '05'
page: 97 - 101
publication: Theoretical Population Biology
publication_status: published
publisher: Academic Press
publist_id: '5236'
quality_controlled: 0
status: public
title: The number of equilibria in the diallelic Levene model with multiple demes
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
volume: 79
year: '2011'
...
---
_id: '1973'
abstract:
- lang: eng
text: Complex I is the first and largest enzyme of the respiratory chain, coupling
electron transfer between NADH and ubiquinone to the translocation of four protons
across the membrane. It has a central role in cellular energy production and has
been implicated in many human neurodegenerative diseases. The L-shaped enzyme
consists of hydrophilic and membrane domains. Previously, we determined the structure
of the hydrophilic domain. Here we report the crystal structure of the Esherichia
coli complex I membrane domain at 3.0 Ã. resolution. It includes six subunits,
NuoL, NuoM, NuoN, NuoA, NuoJ and NuoK, with 55 transmembrane helices. The fold
of the homologous antiporter-like subunits L, M and N is novel, with two inverted
structural repeats of five transmembrane helices arranged, unusually, face-to-back.
Each repeat includes a discontinuous transmembrane helix and forms half of a channel
across the membrane. A network of conserved polar residues connects the two half-channels,
completing the proton translocation pathway. Unexpectedly, lysines rather than
carboxylate residues act as the main elements of the proton pump in these subunits.
The fourth probable proton-translocation channel is at the interface of subunits
N, K, J and A. The structure indicates that proton translocation in complex I,
uniquely, involves coordinated conformational changes in six symmetrical structural
elements.
acknowledgement: This work was funded by the Medical Research Council.
author:
- first_name: Rouslan
full_name: Efremov, Rouslan G
last_name: Efremov
- first_name: Leonid A
full_name: Leonid Sazanov
id: 338D39FE-F248-11E8-B48F-1D18A9856A87
last_name: Sazanov
orcid: 0000-0002-0977-7989
citation:
ama: Efremov R, Sazanov LA. Structure of the membrane domain of respiratory complex
i. Nature. 2011;476(7361):414-421. doi:10.1038/nature10330
apa: Efremov, R., & Sazanov, L. A. (2011). Structure of the membrane domain
of respiratory complex i. Nature. Nature Publishing Group. https://doi.org/10.1038/nature10330
chicago: Efremov, Rouslan, and Leonid A Sazanov. “Structure of the Membrane Domain
of Respiratory Complex I.” Nature. Nature Publishing Group, 2011. https://doi.org/10.1038/nature10330.
ieee: R. Efremov and L. A. Sazanov, “Structure of the membrane domain of respiratory
complex i,” Nature, vol. 476, no. 7361. Nature Publishing Group, pp. 414–421,
2011.
ista: Efremov R, Sazanov LA. 2011. Structure of the membrane domain of respiratory
complex i. Nature. 476(7361), 414–421.
mla: Efremov, Rouslan, and Leonid A. Sazanov. “Structure of the Membrane Domain
of Respiratory Complex I.” Nature, vol. 476, no. 7361, Nature Publishing
Group, 2011, pp. 414–21, doi:10.1038/nature10330.
short: R. Efremov, L.A. Sazanov, Nature 476 (2011) 414–421.
date_created: 2018-12-11T11:54:59Z
date_published: 2011-08-25T00:00:00Z
date_updated: 2021-01-12T06:54:26Z
day: '25'
doi: 10.1038/nature10330
extern: 1
intvolume: ' 476'
issue: '7361'
month: '08'
page: 414 - 421
publication: Nature
publication_status: published
publisher: Nature Publishing Group
publist_id: '5110'
quality_controlled: 0
status: public
title: Structure of the membrane domain of respiratory complex i
type: journal_article
volume: 476
year: '2011'
...
---
_id: '1974'
abstract:
- lang: eng
text: Complex I is the first enzyme of the respiratory chain and plays a central
role in cellular energy production. It has been implicated in many human neurodegenerative
diseases, as well as in ageing. One of the biggest membrane protein complexes,
it is an L-shaped assembly consisting of hydrophilic and membrane domains. Previously,
we have determined structures of the hydrophilic domain in several redox states.
Last year was marked by fascinating breakthroughs in the understanding of the
complete structure. We described the architecture of the membrane domain and of
the entire bacterial complex I. X-ray analysis of the larger mitochondrial enzyme
has also been published. The core subunits of the bacterial and mitochondrial
enzymes have remarkably similar structures. The proposed mechanism of coupling
between electron transfer and proton translocation involves long-range conformational
changes, coordinated in part by a long α-helix, akin to the coupling rod of a
steam engine.
acknowledgement: The work in authors’ laboratory was funded by the Medical Research
Council.
author:
- first_name: Rouslan
full_name: Efremov, Rouslan G
last_name: Efremov
- first_name: Leonid A
full_name: Leonid Sazanov
id: 338D39FE-F248-11E8-B48F-1D18A9856A87
last_name: Sazanov
orcid: 0000-0002-0977-7989
citation:
ama: 'Efremov R, Sazanov LA. Respiratory complex I: “steam engine” of the cell?
Current Opinion in Structural Biology. 2011;21(4):532-540. doi:10.1016/j.sbi.2011.07.002'
apa: 'Efremov, R., & Sazanov, L. A. (2011). Respiratory complex I: “steam engine”
of the cell? Current Opinion in Structural Biology. Elsevier. https://doi.org/10.1016/j.sbi.2011.07.002'
chicago: 'Efremov, Rouslan, and Leonid A Sazanov. “Respiratory Complex I: ‘steam
Engine’ of the Cell?” Current Opinion in Structural Biology. Elsevier,
2011. https://doi.org/10.1016/j.sbi.2011.07.002.'
ieee: 'R. Efremov and L. A. Sazanov, “Respiratory complex I: ‘steam engine’ of the
cell?,” Current Opinion in Structural Biology, vol. 21, no. 4. Elsevier,
pp. 532–540, 2011.'
ista: 'Efremov R, Sazanov LA. 2011. Respiratory complex I: ‘steam engine’ of the
cell? Current Opinion in Structural Biology. 21(4), 532–540.'
mla: 'Efremov, Rouslan, and Leonid A. Sazanov. “Respiratory Complex I: ‘steam Engine’
of the Cell?” Current Opinion in Structural Biology, vol. 21, no. 4, Elsevier,
2011, pp. 532–40, doi:10.1016/j.sbi.2011.07.002.'
short: R. Efremov, L.A. Sazanov, Current Opinion in Structural Biology 21 (2011)
532–540.
date_created: 2018-12-11T11:54:59Z
date_published: 2011-08-01T00:00:00Z
date_updated: 2021-01-12T06:54:27Z
day: '01'
doi: 10.1016/j.sbi.2011.07.002
extern: 1
intvolume: ' 21'
issue: '4'
month: '08'
page: 532 - 540
publication: Current Opinion in Structural Biology
publication_status: published
publisher: Elsevier
publist_id: '5111'
quality_controlled: 0
status: public
title: 'Respiratory complex I: ''steam engine'' of the cell?'
type: journal_article
volume: 21
year: '2011'
...