---
_id: '15025'
abstract:
- lang: eng
  text: We consider quadratic forms of deterministic matrices A evaluated at the random
    eigenvectors of a large N×N GOE or GUE matrix, or equivalently evaluated at the
    columns of a Haar-orthogonal or Haar-unitary random matrix. We prove that, as
    long as the deterministic matrix has rank much smaller than √N, the distributions
    of the extrema of these quadratic forms are asymptotically the same as if the
    eigenvectors were independent Gaussians. This reduces the problem to Gaussian
    computations, which we carry out in several cases to illustrate our result, finding
    Gumbel or Weibull limiting distributions depending on the signature of A. Our
    result also naturally applies to the eigenvectors of any invariant ensemble.
acknowledgement: The first author was supported by the ERC Advanced Grant “RMTBeyond”
  No. 101020331. The second author was supported by Fulbright Austria and the Austrian
  Marshall Plan Foundation.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: László
  full_name: Erdös, László
  id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
  last_name: Erdös
  orcid: 0000-0001-5366-9603
- first_name: Benjamin
  full_name: McKenna, Benjamin
  id: b0cc634c-d549-11ee-96c8-87338c7ad808
  last_name: McKenna
  orcid: 0000-0003-2625-495X
citation:
  ama: Erdös L, McKenna B. Extremal statistics of quadratic forms of GOE/GUE eigenvectors.
    <i>Annals of Applied Probability</i>. 2024;34(1B):1623-1662. doi:<a href="https://doi.org/10.1214/23-AAP2000">10.1214/23-AAP2000</a>
  apa: Erdös, L., &#38; McKenna, B. (2024). Extremal statistics of quadratic forms
    of GOE/GUE eigenvectors. <i>Annals of Applied Probability</i>. Institute of Mathematical
    Statistics. <a href="https://doi.org/10.1214/23-AAP2000">https://doi.org/10.1214/23-AAP2000</a>
  chicago: Erdös, László, and Benjamin McKenna. “Extremal Statistics of Quadratic
    Forms of GOE/GUE Eigenvectors.” <i>Annals of Applied Probability</i>. Institute
    of Mathematical Statistics, 2024. <a href="https://doi.org/10.1214/23-AAP2000">https://doi.org/10.1214/23-AAP2000</a>.
  ieee: L. Erdös and B. McKenna, “Extremal statistics of quadratic forms of GOE/GUE
    eigenvectors,” <i>Annals of Applied Probability</i>, vol. 34, no. 1B. Institute
    of Mathematical Statistics, pp. 1623–1662, 2024.
  ista: Erdös L, McKenna B. 2024. Extremal statistics of quadratic forms of GOE/GUE
    eigenvectors. Annals of Applied Probability. 34(1B), 1623–1662.
  mla: Erdös, László, and Benjamin McKenna. “Extremal Statistics of Quadratic Forms
    of GOE/GUE Eigenvectors.” <i>Annals of Applied Probability</i>, vol. 34, no. 1B,
    Institute of Mathematical Statistics, 2024, pp. 1623–62, doi:<a href="https://doi.org/10.1214/23-AAP2000">10.1214/23-AAP2000</a>.
  short: L. Erdös, B. McKenna, Annals of Applied Probability 34 (2024) 1623–1662.
date_created: 2024-02-25T23:00:56Z
date_published: 2024-02-01T00:00:00Z
date_updated: 2024-02-27T08:29:05Z
day: '01'
department:
- _id: LaEr
doi: 10.1214/23-AAP2000
ec_funded: 1
external_id:
  arxiv:
  - '2208.12206'
intvolume: '        34'
issue: 1B
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2208.12206
month: '02'
oa: 1
oa_version: Preprint
page: 1623-1662
project:
- _id: 62796744-2b32-11ec-9570-940b20777f1d
  call_identifier: H2020
  grant_number: '101020331'
  name: Random matrices beyond Wigner-Dyson-Mehta
publication: Annals of Applied Probability
publication_identifier:
  issn:
  - 1050-5164
publication_status: published
publisher: Institute of Mathematical Statistics
quality_controlled: '1'
scopus_import: '1'
status: public
title: Extremal statistics of quadratic forms of GOE/GUE eigenvectors
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 34
year: '2024'
...
---
_id: '15033'
abstract:
- lang: eng
  text: The GNOM (GN) Guanine nucleotide Exchange Factor for ARF small GTPases (ARF-GEF)
    is among the best studied trafficking regulators in plants, playing crucial and
    unique developmental roles in patterning and polarity. The current models place
    GN at the Golgi apparatus (GA), where it mediates secretion/recycling, and at
    the plasma membrane (PM) presumably contributing to clathrin-mediated endocytosis
    (CME). The mechanistic basis of the developmental function of GN, distinct from
    the other ARF-GEFs including its closest homologue GNOM-LIKE1 (GNL1), remains
    elusive. Insights from this study largely extend the current notions of GN function.
    We show that GN, but not GNL1, localizes to the cell periphery at long-lived structures
    distinct from clathrin-coated pits, while CME and secretion proceed normally in
    <jats:italic>gn</jats:italic> knockouts. The functional GN mutant variant GN<jats:sup>fewerroots</jats:sup>,
    absent from the GA, suggests that the cell periphery is the major site of GN action
    responsible for its developmental function. Following inhibition by Brefeldin
    A, GN, but not GNL1, relocates to the PM likely on exocytic vesicles, suggesting
    selective molecular associations en route to the cell periphery. A study of GN-GNL1
    chimeric ARF-GEFs indicates that all GN domains contribute to the specific GN
    function in a partially redundant manner. Together, this study offers significant
    steps toward the elucidation of the mechanism underlying unique cellular and development
    functions of GNOM.
acknowledgement: "The authors would like to gratefully acknowledge Dr Xixi Zhang for
  cloning the GNL1/pDONR221 construct and for useful discussions.H2020 European Research\r\nCouncil
  Advanced Grant ETAP742985 to Jiří Friml, Austrian Science Fund I 3630-B25 to Jiří
  Friml"
article_processing_charge: Yes
article_type: original
author:
- first_name: Maciek
  full_name: Adamowski, Maciek
  id: 45F536D2-F248-11E8-B48F-1D18A9856A87
  last_name: Adamowski
  orcid: 0000-0001-6463-5257
- first_name: Ivana
  full_name: Matijevic, Ivana
  id: 83c17ce3-15b2-11ec-abd3-f486545870bd
  last_name: Matijevic
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: Adamowski M, Matijevic I, Friml J. Developmental patterning function of GNOM
    ARF-GEF mediated from the cell periphery. <i>eLife</i>. 2024;13. doi:<a href="https://doi.org/10.7554/elife.68993">10.7554/elife.68993</a>
  apa: Adamowski, M., Matijevic, I., &#38; Friml, J. (2024). Developmental patterning
    function of GNOM ARF-GEF mediated from the cell periphery. <i>ELife</i>. eLife
    Sciences Publications. <a href="https://doi.org/10.7554/elife.68993">https://doi.org/10.7554/elife.68993</a>
  chicago: Adamowski, Maciek, Ivana Matijevic, and Jiří Friml. “Developmental Patterning
    Function of GNOM ARF-GEF Mediated from the Cell Periphery.” <i>ELife</i>. eLife
    Sciences Publications, 2024. <a href="https://doi.org/10.7554/elife.68993">https://doi.org/10.7554/elife.68993</a>.
  ieee: M. Adamowski, I. Matijevic, and J. Friml, “Developmental patterning function
    of GNOM ARF-GEF mediated from the cell periphery,” <i>eLife</i>, vol. 13. eLife
    Sciences Publications, 2024.
  ista: Adamowski M, Matijevic I, Friml J. 2024. Developmental patterning function
    of GNOM ARF-GEF mediated from the cell periphery. eLife. 13.
  mla: Adamowski, Maciek, et al. “Developmental Patterning Function of GNOM ARF-GEF
    Mediated from the Cell Periphery.” <i>ELife</i>, vol. 13, eLife Sciences Publications,
    2024, doi:<a href="https://doi.org/10.7554/elife.68993">10.7554/elife.68993</a>.
  short: M. Adamowski, I. Matijevic, J. Friml, ELife 13 (2024).
date_created: 2024-02-27T07:10:11Z
date_published: 2024-02-21T00:00:00Z
date_updated: 2024-02-28T12:29:43Z
day: '21'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.7554/elife.68993
ec_funded: 1
has_accepted_license: '1'
intvolume: '        13'
keyword:
- General Immunology and Microbiology
- General Biochemistry
- Genetics and Molecular Biology
- General Medicine
- General Neuroscience
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.7554/eLife.68993
month: '02'
oa: 1
oa_version: Published Version
project:
- _id: 261099A6-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '742985'
  name: Tracing Evolution of Auxin Transport and Polarity in Plants
- _id: 26538374-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: I03630
  name: Molecular mechanisms of endocytic cargo recognition in plants
publication: eLife
publication_identifier:
  issn:
  - 2050-084X
publication_status: epub_ahead
publisher: eLife Sciences Publications
quality_controlled: '1'
status: public
title: Developmental patterning function of GNOM ARF-GEF mediated from the cell periphery
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 13
year: '2024'
...
---
_id: '15045'
abstract:
- lang: eng
  text: Coupling of orbital motion to a spin degree of freedom gives rise to various
    transport phenomena in quantum systems that are beyond the standard paradigms
    of classical physics. Here, we discuss features of spin-orbit dynamics that can
    be visualized using a classical model with two coupled angular degrees of freedom.
    Specifically, we demonstrate classical ‘spin’ filtering through our model and
    show that the interplay between angular degrees of freedom and dissipation can
    lead to asymmetric ‘spin’ transport.
acknowledgement: "We thank Mikhail Lemeshko and members of his group for many inspiring
  discussions; Alberto Cappellaro for comments on the manuscript.\r\nOpen access funding
  provided by Institute of Science and Technology (IST Austria)."
article_number: '12'
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Atul
  full_name: Varshney, Atul
  id: 2A2006B2-F248-11E8-B48F-1D18A9856A87
  last_name: Varshney
  orcid: 0000-0002-3072-5999
- first_name: Areg
  full_name: Ghazaryan, Areg
  id: 4AF46FD6-F248-11E8-B48F-1D18A9856A87
  last_name: Ghazaryan
  orcid: 0000-0001-9666-3543
- first_name: Artem
  full_name: Volosniev, Artem
  id: 37D278BC-F248-11E8-B48F-1D18A9856A87
  last_name: Volosniev
  orcid: 0000-0003-0393-5525
citation:
  ama: Varshney A, Ghazaryan A, Volosniev A. Classical ‘spin’ filtering with two degrees
    of freedom and dissipation. <i>Few-Body Systems</i>. 2024;65. doi:<a href="https://doi.org/10.1007/s00601-024-01880-x">10.1007/s00601-024-01880-x</a>
  apa: Varshney, A., Ghazaryan, A., &#38; Volosniev, A. (2024). Classical ‘spin’ filtering
    with two degrees of freedom and dissipation. <i>Few-Body Systems</i>. Springer
    Nature. <a href="https://doi.org/10.1007/s00601-024-01880-x">https://doi.org/10.1007/s00601-024-01880-x</a>
  chicago: Varshney, Atul, Areg Ghazaryan, and Artem Volosniev. “Classical ‘Spin’
    Filtering with Two Degrees of Freedom and Dissipation.” <i>Few-Body Systems</i>.
    Springer Nature, 2024. <a href="https://doi.org/10.1007/s00601-024-01880-x">https://doi.org/10.1007/s00601-024-01880-x</a>.
  ieee: A. Varshney, A. Ghazaryan, and A. Volosniev, “Classical ‘spin’ filtering with
    two degrees of freedom and dissipation,” <i>Few-Body Systems</i>, vol. 65. Springer
    Nature, 2024.
  ista: Varshney A, Ghazaryan A, Volosniev A. 2024. Classical ‘spin’ filtering with
    two degrees of freedom and dissipation. Few-Body Systems. 65, 12.
  mla: Varshney, Atul, et al. “Classical ‘Spin’ Filtering with Two Degrees of Freedom
    and Dissipation.” <i>Few-Body Systems</i>, vol. 65, 12, Springer Nature, 2024,
    doi:<a href="https://doi.org/10.1007/s00601-024-01880-x">10.1007/s00601-024-01880-x</a>.
  short: A. Varshney, A. Ghazaryan, A. Volosniev, Few-Body Systems 65 (2024).
date_created: 2024-03-01T11:39:33Z
date_published: 2024-02-17T00:00:00Z
date_updated: 2024-03-04T07:08:16Z
day: '17'
ddc:
- '530'
department:
- _id: MiLe
doi: 10.1007/s00601-024-01880-x
external_id:
  arxiv:
  - '2401.08454'
file:
- access_level: open_access
  checksum: c4e08cc7bc756da69b1b36fda7bb92fb
  content_type: application/pdf
  creator: dernst
  date_created: 2024-03-04T07:07:10Z
  date_updated: 2024-03-04T07:07:10Z
  file_id: '15049'
  file_name: 2024_FewBodySys_Varshney.pdf
  file_size: 436712
  relation: main_file
  success: 1
file_date_updated: 2024-03-04T07:07:10Z
has_accepted_license: '1'
intvolume: '        65'
keyword:
- Atomic and Molecular Physics
- and Optics
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
publication: Few-Body Systems
publication_identifier:
  issn:
  - 1432-5411
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Classical ‘spin’ filtering with two degrees of freedom and dissipation
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 65
year: '2024'
...
---
_id: '15047'
abstract:
- lang: eng
  text: Tropical precipitation extremes and their changes with surface warming are
    investigated using global storm resolving simulations and high-resolution observations.
    The simulations demonstrate that the mesoscale organization of convection, a process
    that cannot be physically represented by conventional global climate models, is
    important for the variations of tropical daily accumulated precipitation extremes.
    In both the simulations and observations, daily precipitation extremes increase
    in a more organized state, in association with larger, but less frequent, storms.
    Repeating the simulations for a warmer climate results in a robust increase in
    monthly-mean daily precipitation extremes. Higher precipitation percentiles have
    a greater sensitivity to convective organization, which is predicted to increase
    with warming. Without changes in organization, the strongest daily precipitation
    extremes over the tropical oceans increase at a rate close to Clausius-Clapeyron
    (CC) scaling. Thus, in a future warmer state with increased organization, the
    strongest daily precipitation extremes over oceans increase at a faster rate than
    CC scaling.
acknowledgement: This work is supported by the Max-Planck-Gesellschaft (MPG). We greatly
  appreciate computational resources from Deutsches Klimarechenzentrum (DKRZ) and
  the Jülich Supercomputing Centre (JSC). ICONA/O simulations are funded through the
  NextGEMS project by the EU’s Horizon 2020 programme (grant agreement no. 101003470).
  ICONA simulations are funded through the MONSOON-2.0 project (grant agreement no.
  01LP1927A) which is supported from German Federal Ministry of Education and Research
  (BMBF). J.B. acknowledges funding from the European Union’s Horizon 2020 research
  and innovation programme under the Marie Skłodowska-Curie grant (grant agreement
  no. 101034413). B.S. acknowledges funding from the EU’s Horizon 2020 programme (grant
  agreement no. 101003470). C.M. gratefully acknowledges funding from the European
  Research Council (ERC) under the European Union’s Horizon 2020 research and innovation
  program (Project CLUSTER, grant agreement no. 805041).
article_number: eadj6801
article_processing_charge: Yes
article_type: original
author:
- first_name: Jiawei
  full_name: Bao, Jiawei
  id: bb9a7399-fefd-11ed-be3c-ae648fd1d160
  last_name: Bao
- first_name: Bjorn
  full_name: Stevens, Bjorn
  last_name: Stevens
- first_name: Lukas
  full_name: Kluft, Lukas
  last_name: Kluft
- first_name: Caroline J
  full_name: Muller, Caroline J
  id: f978ccb0-3f7f-11eb-b193-b0e2bd13182b
  last_name: Muller
  orcid: 0000-0001-5836-5350
citation:
  ama: Bao J, Stevens B, Kluft L, Muller CJ. Intensification of daily tropical precipitation
    extremes from more organized convection. <i>Science Advances</i>. 2024;10(8).
    doi:<a href="https://doi.org/10.1126/sciadv.adj6801">10.1126/sciadv.adj6801</a>
  apa: Bao, J., Stevens, B., Kluft, L., &#38; Muller, C. J. (2024). Intensification
    of daily tropical precipitation extremes from more organized convection. <i>Science
    Advances</i>. American Association for the Advancement of Science. <a href="https://doi.org/10.1126/sciadv.adj6801">https://doi.org/10.1126/sciadv.adj6801</a>
  chicago: Bao, Jiawei, Bjorn Stevens, Lukas Kluft, and Caroline J Muller. “Intensification
    of Daily Tropical Precipitation Extremes from More Organized Convection.” <i>Science
    Advances</i>. American Association for the Advancement of Science, 2024. <a href="https://doi.org/10.1126/sciadv.adj6801">https://doi.org/10.1126/sciadv.adj6801</a>.
  ieee: J. Bao, B. Stevens, L. Kluft, and C. J. Muller, “Intensification of daily
    tropical precipitation extremes from more organized convection,” <i>Science Advances</i>,
    vol. 10, no. 8. American Association for the Advancement of Science, 2024.
  ista: Bao J, Stevens B, Kluft L, Muller CJ. 2024. Intensification of daily tropical
    precipitation extremes from more organized convection. Science Advances. 10(8),
    eadj6801.
  mla: Bao, Jiawei, et al. “Intensification of Daily Tropical Precipitation Extremes
    from More Organized Convection.” <i>Science Advances</i>, vol. 10, no. 8, eadj6801,
    American Association for the Advancement of Science, 2024, doi:<a href="https://doi.org/10.1126/sciadv.adj6801">10.1126/sciadv.adj6801</a>.
  short: J. Bao, B. Stevens, L. Kluft, C.J. Muller, Science Advances 10 (2024).
date_created: 2024-03-03T23:00:50Z
date_published: 2024-02-23T00:00:00Z
date_updated: 2024-03-05T09:26:47Z
day: '23'
ddc:
- '550'
department:
- _id: CaMu
doi: 10.1126/sciadv.adj6801
ec_funded: 1
external_id:
  pmid:
  - '38394192'
file:
- access_level: open_access
  checksum: d4ec4f05a6d14745057e14d1b8bf45ae
  content_type: application/pdf
  creator: dernst
  date_created: 2024-03-04T07:34:00Z
  date_updated: 2024-03-04T07:34:00Z
  file_id: '15051'
  file_name: 2024_ScienceAdv_Bao.pdf
  file_size: 800926
  relation: main_file
  success: 1
file_date_updated: 2024-03-04T07:34:00Z
has_accepted_license: '1'
intvolume: '        10'
issue: '8'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
  call_identifier: H2020
  grant_number: '101034413'
  name: 'IST-BRIDGE: International postdoctoral program'
- _id: 629205d8-2b32-11ec-9570-e1356ff73576
  call_identifier: H2020
  grant_number: '805041'
  name: organization of CLoUdS, and implications of Tropical  cyclones and for the
    Energetics of the tropics, in current and waRming climate
publication: Science Advances
publication_identifier:
  eissn:
  - 2375-2548
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
related_material:
  link:
  - description: News on ISTA Website
    relation: press_release
    url: https://ista.ac.at/en/news/cloud-clustering-causes-more-extreme-rain/
scopus_import: '1'
status: public
title: Intensification of daily tropical precipitation extremes from more organized
  convection
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 10
year: '2024'
...
---
_id: '15048'
abstract:
- lang: eng
  text: Embryogenesis results from the coordinated activities of different signaling
    pathways controlling cell fate specification and morphogenesis. In vertebrate
    gastrulation, both Nodal and BMP signaling play key roles in germ layer specification
    and morphogenesis, yet their interplay to coordinate embryo patterning with morphogenesis
    is still insufficiently understood. Here, we took a reductionist approach using
    zebrafish embryonic explants to study the coordination of Nodal and BMP signaling
    for embryo patterning and morphogenesis. We show that Nodal signaling triggers
    explant elongation by inducing mesendodermal progenitors but also suppressing
    BMP signaling activity at the site of mesendoderm induction. Consistent with this,
    ectopic BMP signaling in the mesendoderm blocks cell alignment and oriented mesendoderm
    intercalations, key processes during explant elongation. Translating these ex
    vivo observations to the intact embryo showed that, similar to explants, Nodal
    signaling suppresses the effect of BMP signaling on cell intercalations in the
    dorsal domain, thus allowing robust embryonic axis elongation. These findings
    suggest a dual function of Nodal signaling in embryonic axis elongation by both
    inducing mesendoderm and suppressing BMP effects in the dorsal portion of the
    mesendoderm.
acknowledged_ssus:
- _id: Bio
- _id: LifeSc
acknowledgement: "We thank Patrick Müller for sharing the chordintt250 mutant zebrafish
  line as well as the plasmid for chrd-GFP, Katherine Rogers for sharing the bmp2b
  plasmid and Andrea Pauli for sharing the draculin plasmid. Diana Pinheiro generated
  the MZlefty1,2;Tg(sebox::EGFP) line. We are grateful to Patrick Müller, Diana Pinheiro
  and Katherine Rogers and members of the Heisenberg lab for discussions, technical
  advice and feedback on the manuscript. We also thank Anna Kicheva and Edouard Hannezo
  for discussions. We thank the Imaging and Optics Facility as well as the Life Science
  facility at IST Austria for support with microscopy and fish maintenance.\r\nThis
  work was supported by a European Research Council Advanced Grant\r\n(MECSPEC 742573
  to C.-P.H.). A.S. is a recipient of a DOC Fellowship of the Austrian\r\nAcademy
  of Sciences at IST Austria. Open Access funding provided by Institute of\r\nScience
  and Technology Austria. "
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Alexandra
  full_name: Schauer, Alexandra
  id: 30A536BA-F248-11E8-B48F-1D18A9856A87
  last_name: Schauer
  orcid: 0000-0001-7659-9142
- first_name: Kornelija
  full_name: Pranjic-Ferscha, Kornelija
  id: 4362B3C2-F248-11E8-B48F-1D18A9856A87
  last_name: Pranjic-Ferscha
- first_name: Robert
  full_name: Hauschild, Robert
  id: 4E01D6B4-F248-11E8-B48F-1D18A9856A87
  last_name: Hauschild
  orcid: 0000-0001-9843-3522
- first_name: Carl-Philipp J
  full_name: Heisenberg, Carl-Philipp J
  id: 39427864-F248-11E8-B48F-1D18A9856A87
  last_name: Heisenberg
  orcid: 0000-0002-0912-4566
citation:
  ama: Schauer A, Pranjic-Ferscha K, Hauschild R, Heisenberg C-PJ. Robust axis elongation
    by Nodal-dependent restriction of BMP signaling. <i>Development</i>. 2024;151(4):1-18.
    doi:<a href="https://doi.org/10.1242/dev.202316">10.1242/dev.202316</a>
  apa: Schauer, A., Pranjic-Ferscha, K., Hauschild, R., &#38; Heisenberg, C.-P. J.
    (2024). Robust axis elongation by Nodal-dependent restriction of BMP signaling.
    <i>Development</i>. The Company of Biologists. <a href="https://doi.org/10.1242/dev.202316">https://doi.org/10.1242/dev.202316</a>
  chicago: Schauer, Alexandra, Kornelija Pranjic-Ferscha, Robert Hauschild, and Carl-Philipp
    J Heisenberg. “Robust Axis Elongation by Nodal-Dependent Restriction of BMP Signaling.”
    <i>Development</i>. The Company of Biologists, 2024. <a href="https://doi.org/10.1242/dev.202316">https://doi.org/10.1242/dev.202316</a>.
  ieee: A. Schauer, K. Pranjic-Ferscha, R. Hauschild, and C.-P. J. Heisenberg, “Robust
    axis elongation by Nodal-dependent restriction of BMP signaling,” <i>Development</i>,
    vol. 151, no. 4. The Company of Biologists, pp. 1–18, 2024.
  ista: Schauer A, Pranjic-Ferscha K, Hauschild R, Heisenberg C-PJ. 2024. Robust axis
    elongation by Nodal-dependent restriction of BMP signaling. Development. 151(4),
    1–18.
  mla: Schauer, Alexandra, et al. “Robust Axis Elongation by Nodal-Dependent Restriction
    of BMP Signaling.” <i>Development</i>, vol. 151, no. 4, The Company of Biologists,
    2024, pp. 1–18, doi:<a href="https://doi.org/10.1242/dev.202316">10.1242/dev.202316</a>.
  short: A. Schauer, K. Pranjic-Ferscha, R. Hauschild, C.-P.J. Heisenberg, Development
    151 (2024) 1–18.
date_created: 2024-03-03T23:00:50Z
date_published: 2024-02-01T00:00:00Z
date_updated: 2024-03-04T07:28:25Z
day: '01'
ddc:
- '570'
department:
- _id: CaHe
- _id: Bio
doi: 10.1242/dev.202316
ec_funded: 1
file:
- access_level: open_access
  checksum: 6961ea10012bf0d266681f9628bb8f13
  content_type: application/pdf
  creator: dernst
  date_created: 2024-03-04T07:24:43Z
  date_updated: 2024-03-04T07:24:43Z
  file_id: '15050'
  file_name: 2024_Development_Schauer.pdf
  file_size: 14839986
  relation: main_file
  success: 1
file_date_updated: 2024-03-04T07:24:43Z
has_accepted_license: '1'
intvolume: '       151'
issue: '4'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
page: 1-18
project:
- _id: 260F1432-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '742573'
  name: Interaction and feedback between cell mechanics and fate specification in
    vertebrate gastrulation
- _id: 26B1E39C-B435-11E9-9278-68D0E5697425
  grant_number: '25239'
  name: 'Mesendoderm specification in zebrafish: The role of extraembryonic tissues'
publication: Development
publication_identifier:
  eissn:
  - 1477-9129
  issn:
  - 0950-1991
publication_status: published
publisher: The Company of Biologists
quality_controlled: '1'
related_material:
  record:
  - id: '14926'
    relation: research_data
    status: public
scopus_import: '1'
status: public
title: Robust axis elongation by Nodal-dependent restriction of BMP signaling
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 151
year: '2024'
...
---
_id: '15052'
abstract:
- lang: eng
  text: "Substrate induces mechanical strain on perovskite devices, which can result
    in alterations to its lattice dynamics and thermal transport. Herein, we have
    performed a theoretical investigation on the anharmonic lattice dynamics and thermal
    property of perovskite Rb2SnBr6 and Cs2SnBr6 under strains using perturbation
    theory up to the fourth-order terms and the unified thermal transport theory.
    We demonstrate a pronounced hardening of low-frequency optical phonons as temperature
    increases, indicating strong lattice anharmonicity and the necessity of adopting
    temperature-dependent interatomic force constants in the lattice thermal conductivity
    (\r\nκL) calculations. It is found that the low-lying optical phonon modes of
    Rb2SnBr6 are extremely soft and their phonon energies are almost strain independent,
    which ultimately lead to a lower \r\nκL and a weaker strain dependence than Cs2SnBr6.
    We further reveal that the strain dependence of these phonon modes in the A2XB6-type
    perovskites weakens as their ibrational frequency decreases. This study deepens
    the understanding of lattice thermal transport in perovskites A2XB6 and provides
    a perspective on the selection of materials that meet the expected thermal behaviors
    in practical applications."
acknowledgement: "This work is supported by the Research Grants Council of Hong Kong
  (C7002-22Y and 17318122). The authors are grateful for the research computing facilities
  offered by\r\nITS, HKU. Z.Z. acknowledges the European Union’s Horizon 2020 research
  and innovation programme under the Marie Skłodowska-Curie Grant Agreement No. 101034413."
article_number: '054305'
article_processing_charge: No
article_type: original
author:
- first_name: Ruihuan
  full_name: Cheng, Ruihuan
  last_name: Cheng
- first_name: Zezhu
  full_name: Zeng, Zezhu
  id: 54a2c730-803f-11ed-ab7e-95b29d2680e7
  last_name: Zeng
- first_name: Chen
  full_name: Wang, Chen
  last_name: Wang
- first_name: Niuchang
  full_name: Ouyang, Niuchang
  last_name: Ouyang
- first_name: Yue
  full_name: Chen, Yue
  last_name: Chen
citation:
  ama: Cheng R, Zeng Z, Wang C, Ouyang N, Chen Y. Impact of strain-insensitive low-frequency
    phonon modes on lattice thermal transport in AxXB6-type perovskites. <i>Physical
    Review B</i>. 2024;109(5). doi:<a href="https://doi.org/10.1103/physrevb.109.054305">10.1103/physrevb.109.054305</a>
  apa: Cheng, R., Zeng, Z., Wang, C., Ouyang, N., &#38; Chen, Y. (2024). Impact of
    strain-insensitive low-frequency phonon modes on lattice thermal transport in
    AxXB6-type perovskites. <i>Physical Review B</i>. American Physical Society. <a
    href="https://doi.org/10.1103/physrevb.109.054305">https://doi.org/10.1103/physrevb.109.054305</a>
  chicago: Cheng, Ruihuan, Zezhu Zeng, Chen Wang, Niuchang Ouyang, and Yue Chen. “Impact
    of Strain-Insensitive Low-Frequency Phonon Modes on Lattice Thermal Transport
    in AxXB6-Type Perovskites.” <i>Physical Review B</i>. American Physical Society,
    2024. <a href="https://doi.org/10.1103/physrevb.109.054305">https://doi.org/10.1103/physrevb.109.054305</a>.
  ieee: R. Cheng, Z. Zeng, C. Wang, N. Ouyang, and Y. Chen, “Impact of strain-insensitive
    low-frequency phonon modes on lattice thermal transport in AxXB6-type perovskites,”
    <i>Physical Review B</i>, vol. 109, no. 5. American Physical Society, 2024.
  ista: Cheng R, Zeng Z, Wang C, Ouyang N, Chen Y. 2024. Impact of strain-insensitive
    low-frequency phonon modes on lattice thermal transport in AxXB6-type perovskites.
    Physical Review B. 109(5), 054305.
  mla: Cheng, Ruihuan, et al. “Impact of Strain-Insensitive Low-Frequency Phonon Modes
    on Lattice Thermal Transport in AxXB6-Type Perovskites.” <i>Physical Review B</i>,
    vol. 109, no. 5, 054305, American Physical Society, 2024, doi:<a href="https://doi.org/10.1103/physrevb.109.054305">10.1103/physrevb.109.054305</a>.
  short: R. Cheng, Z. Zeng, C. Wang, N. Ouyang, Y. Chen, Physical Review B 109 (2024).
date_created: 2024-03-04T07:41:23Z
date_published: 2024-02-14T00:00:00Z
date_updated: 2024-03-04T07:48:55Z
day: '14'
department:
- _id: BiCh
doi: 10.1103/physrevb.109.054305
ec_funded: 1
intvolume: '       109'
issue: '5'
language:
- iso: eng
month: '02'
oa_version: None
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
  call_identifier: H2020
  grant_number: '101034413'
  name: 'IST-BRIDGE: International postdoctoral program'
publication: Physical Review B
publication_identifier:
  eissn:
  - 2469-9969
  issn:
  - 2469-9950
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Impact of strain-insensitive low-frequency phonon modes on lattice thermal
  transport in AxXB6-type perovskites
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 109
year: '2024'
...
---
_id: '15053'
abstract:
- lang: eng
  text: Atom-based quantum simulators have had many successes in tackling challenging
    quantum many-body problems, owing to the precise and dynamical control that they
    provide over the systems' parameters. They are, however, often optimized to address
    a specific type of problem. Here, we present the design and implementation of
    a 6Li-based quantum gas platform that provides wide-ranging capabilities and is
    able to address a variety of quantum many-body problems. Our two-chamber architecture
    relies on a robust combination of gray molasses and optical transport from a laser-cooling
    chamber to a glass cell with excellent optical access. There, we first create
    unitary Fermi superfluids in a three-dimensional axially symmetric harmonic trap
    and characterize them using in situ thermometry, reaching temperatures below 20
    nK. This allows us to enter the deep superfluid regime with samples of extreme
    diluteness, where the interparticle spacing is sufficiently large for direct single-atom
    imaging. Second, we generate optical lattice potentials with triangular and honeycomb
    geometry in which we study diffraction of molecular Bose-Einstein condensates,
    and show how going beyond the Kapitza-Dirac regime allows us to unambiguously
    distinguish between the two geometries. With the ability to probe quantum many-body
    physics in both discrete and continuous space, and its suitability for bulk and
    single-atom imaging, our setup represents an important step towards achieving
    a wide-scope quantum simulator.
acknowledgement: We thank Clara Bachorz, Darby Bates, Markus Bohlen, Valentin Crépel,
  Yann Kiefer, Joanna Lis, Mihail Rabinovic, and Julian Struck for experimental assistance
  in the early stages of this project, and Sebastian Will for a critical reading of
  the manuscript. This work has been supported by Agence Nationale de la Recherche
  (Grant No. ANR-21-CE30-0021), the European Research Council (Grant No. ERC-2016-ADG-743159),
  CNRS (Tremplin@INP 2020), and Région Ile-de-France in the framework of DIM SIRTEQ
  (Super2D and SISCo) and DIM QuanTiP.
article_number: '013158'
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Shuwei
  full_name: Jin, Shuwei
  last_name: Jin
- first_name: Kunlun
  full_name: Dai, Kunlun
  last_name: Dai
- first_name: Joris
  full_name: Verstraten, Joris
  last_name: Verstraten
- first_name: Maxime
  full_name: Dixmerias, Maxime
  last_name: Dixmerias
- first_name: Ragheed
  full_name: Al Hyder, Ragheed
  id: d1c405be-ae15-11ed-8510-ccf53278162e
  last_name: Al Hyder
- first_name: Christophe
  full_name: Salomon, Christophe
  last_name: Salomon
- first_name: Bruno
  full_name: Peaudecerf, Bruno
  last_name: Peaudecerf
- first_name: Tim
  full_name: de Jongh, Tim
  last_name: de Jongh
- first_name: Tarik
  full_name: Yefsah, Tarik
  last_name: Yefsah
citation:
  ama: Jin S, Dai K, Verstraten J, et al. Multipurpose platform for analog quantum
    simulation. <i>Physical Review Research</i>. 2024;6(1). doi:<a href="https://doi.org/10.1103/physrevresearch.6.013158">10.1103/physrevresearch.6.013158</a>
  apa: Jin, S., Dai, K., Verstraten, J., Dixmerias, M., Al Hyder, R., Salomon, C.,
    … Yefsah, T. (2024). Multipurpose platform for analog quantum simulation. <i>Physical
    Review Research</i>. American Physical Society. <a href="https://doi.org/10.1103/physrevresearch.6.013158">https://doi.org/10.1103/physrevresearch.6.013158</a>
  chicago: Jin, Shuwei, Kunlun Dai, Joris Verstraten, Maxime Dixmerias, Ragheed Al
    Hyder, Christophe Salomon, Bruno Peaudecerf, Tim de Jongh, and Tarik Yefsah. “Multipurpose
    Platform for Analog Quantum Simulation.” <i>Physical Review Research</i>. American
    Physical Society, 2024. <a href="https://doi.org/10.1103/physrevresearch.6.013158">https://doi.org/10.1103/physrevresearch.6.013158</a>.
  ieee: S. Jin <i>et al.</i>, “Multipurpose platform for analog quantum simulation,”
    <i>Physical Review Research</i>, vol. 6, no. 1. American Physical Society, 2024.
  ista: Jin S, Dai K, Verstraten J, Dixmerias M, Al Hyder R, Salomon C, Peaudecerf
    B, de Jongh T, Yefsah T. 2024. Multipurpose platform for analog quantum simulation.
    Physical Review Research. 6(1), 013158.
  mla: Jin, Shuwei, et al. “Multipurpose Platform for Analog Quantum Simulation.”
    <i>Physical Review Research</i>, vol. 6, no. 1, 013158, American Physical Society,
    2024, doi:<a href="https://doi.org/10.1103/physrevresearch.6.013158">10.1103/physrevresearch.6.013158</a>.
  short: S. Jin, K. Dai, J. Verstraten, M. Dixmerias, R. Al Hyder, C. Salomon, B.
    Peaudecerf, T. de Jongh, T. Yefsah, Physical Review Research 6 (2024).
date_created: 2024-03-04T07:42:52Z
date_published: 2024-02-13T00:00:00Z
date_updated: 2024-03-04T07:55:29Z
day: '13'
ddc:
- '530'
department:
- _id: MiLe
doi: 10.1103/physrevresearch.6.013158
external_id:
  arxiv:
  - '2304.08433'
file:
- access_level: open_access
  checksum: ba2ae3e3a011f8897d3803c9366a67e2
  content_type: application/pdf
  creator: dernst
  date_created: 2024-03-04T07:53:08Z
  date_updated: 2024-03-04T07:53:08Z
  file_id: '15054'
  file_name: 2024_PhysicalReviewResearch_Jin.pdf
  file_size: 4025988
  relation: main_file
  success: 1
file_date_updated: 2024-03-04T07:53:08Z
has_accepted_license: '1'
intvolume: '         6'
issue: '1'
keyword:
- General Physics and Astronomy
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
publication: Physical Review Research
publication_identifier:
  issn:
  - 2643-1564
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Multipurpose platform for analog quantum simulation
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2024'
...
---
_id: '15177'
article_processing_charge: No
author:
- first_name: Doris
  full_name: Ernst, Doris
  id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
  last_name: Ernst
  orcid: 0000-0002-2354-0195
date_created: 2024-06-11T10:04:54Z
date_published: 2024-01-01T00:00:00Z
date_updated: 2024-06-11T10:05:06Z
department:
- _id: E-Lib
oa_version: None
publisher: ISTA
status: public
title: RD Ref
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2024'
...
---
_id: '15262'
article_processing_charge: No
author:
- first_name: Doris
  full_name: Ernst, Doris
  id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
  last_name: Ernst
  orcid: 0000-0002-2354-0195
date_created: 2024-11-18T14:11:31Z
date_published: 2024-11-18T00:00:00Z
date_updated: 2024-11-19T09:19:59Z
day: '18'
department:
- _id: E-Lib
ec_funded: 1
language:
- iso: eng
month: '11'
oa_version: None
project:
- _id: 42f76822-911d-11ef-982b-ce758d810b28
  grant_number: AB123
  name: A Test Grant
- _id: 26336814-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '758053'
  name: A Fiber Optic Transceiver for Superconducting Qubits
- _id: 4b739304-2d65-11ef-919e-fdbedb4a0279
  grant_number: '345'
  name: Aagain a test
publication: Today
status: public
title: Doris Test 18.11.
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2024'
...
---
_id: '14213'
abstract:
- lang: eng
  text: We introduce a method to segment the visual field into independently moving
    regions, trained with no ground truth or supervision. It consists of an adversarial
    conditional encoder-decoder architecture based on Slot Attention, modified to
    use the image as context to decode optical flow without attempting to reconstruct
    the image itself. In the resulting multi-modal representation, one modality (flow)
    feeds the encoder to produce separate latent codes (slots), whereas the other
    modality (image) conditions the decoder to generate the first (flow) from the
    slots. This design frees the representation from having to encode complex nuisance
    variability in the image due to, for instance, illumination and reflectance properties
    of the scene. Since customary autoencoding based on minimizing the reconstruction
    error does not preclude the entire flow from being encoded into a single slot,
    we modify the loss to an adversarial criterion based on Contextual Information
    Separation. The resulting min-max optimization fosters the separation of objects
    and their assignment to different attention slots, leading to Divided Attention,
    or DivA. DivA outperforms recent unsupervised multi-object motion segmentation
    methods while tripling run-time speed up to 104FPS and reducing the performance
    gap from supervised methods to 12% or less. DivA can handle different numbers
    of objects and different image sizes at training and test time, is invariant to
    permutation of object labels, and does not require explicit regularization.
article_processing_charge: No
arxiv: 1
author:
- first_name: Dong
  full_name: Lao, Dong
  last_name: Lao
- first_name: Zhengyang
  full_name: Hu, Zhengyang
  last_name: Hu
- first_name: Francesco
  full_name: Locatello, Francesco
  id: 26cfd52f-2483-11ee-8040-88983bcc06d4
  last_name: Locatello
  orcid: 0000-0002-4850-0683
- first_name: Yanchao
  full_name: Yang, Yanchao
  last_name: Yang
- first_name: Stefano
  full_name: Soatto, Stefano
  last_name: Soatto
conference:
  end_date: 2024-01-03
  location: Hong Kong, China
  name: 'CPAL: Conference on Parsimony and Learning'
  start_date: 2024-01-03
date_created: 2023-08-22T14:19:59Z
date_published: 2024-01-03T00:00:00Z
date_updated: 2025-02-13T08:10:28Z
day: '03'
ddc:
- '000'
department:
- _id: FrLo
external_id:
  arxiv:
  - '2304.01430'
file:
- access_level: open_access
  checksum: 8fad894c34f1b3d5a14fb8ffb12f7277
  content_type: application/pdf
  creator: dernst
  date_created: 2024-02-12T08:40:36Z
  date_updated: 2024-02-12T08:40:36Z
  file_id: '14978'
  file_name: 2024_CPAL_Lao.pdf
  file_size: 8038511
  relation: main_file
  success: 1
file_date_updated: 2024-02-12T08:40:36Z
has_accepted_license: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
publication: 1st Conference on Parsimony and Learning
publication_identifier:
  issnl:
  - 1234-4321
publication_status: published
quality_controlled: '1'
status: public
title: 'Divided attention: Unsupervised multi-object discovery with contextually separated
  slots'
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2024'
...
---
_id: '14251'
abstract:
- lang: eng
  text: The phytohormone auxin and its directional transport through tissues play
    a fundamental role in development of higher plants. This polar auxin transport
    predominantly relies on PIN-FORMED (PIN) auxin exporters. Hence, PIN polarization
    is crucial for development, but its evolution during the rise of morphological
    complexity in land plants remains unclear. Here, we performed a cross-species
    investigation by observing the trafficking and localization of endogenous and
    exogenous PINs in two bryophytes, Physcomitrium patens and Marchantia polymorpha,
    and in the flowering plant Arabidopsis thaliana. We confirmed that the GFP fusion
    did not compromise the auxin export function of all examined PINs by using radioactive
    auxin export assay and by observing the phenotypic changes in transgenic bryophytes.
    Endogenous PINs polarize to filamentous apices, while exogenous Arabidopsis PINs
    distribute symmetrically on the membrane in both bryophytes. In Arabidopsis root
    epidermis, bryophytic PINs show no defined polarity. Pharmacological interference
    revealed a strong cytoskeleton dependence of bryophytic but not Arabidopsis PIN
    polarization. The divergence of PIN polarization and trafficking is also observed
    within the bryophyte clade and between tissues of individual species. These results
    collectively reveal a divergence of PIN trafficking and polarity mechanisms throughout
    land plant evolution and a co-evolution of PIN sequence-based and cell-based polarity
    mechanisms.
acknowledgement: This work was supported by the ERC grant (PR1023ERC02) to H. T. and
  J. F., and by the ministry of science and technology (grant number 110-2636-B-005-001)
  to K. J. L.
article_number: '100669'
article_processing_charge: Yes
article_type: original
author:
- first_name: Han
  full_name: Tang, Han
  id: 19BDF720-25A0-11EA-AC6E-928F3DDC885E
  last_name: Tang
  orcid: 0000-0001-6152-6637
- first_name: KJ
  full_name: Lu, KJ
  last_name: Lu
- first_name: Y
  full_name: Zhang, Y
  last_name: Zhang
- first_name: YL
  full_name: Cheng, YL
  last_name: Cheng
- first_name: SL
  full_name: Tu, SL
  last_name: Tu
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: Tang H, Lu K, Zhang Y, Cheng Y, Tu S, Friml J. Divergence of trafficking and
    polarization mechanisms for PIN auxin transporters during land plant evolution.
    <i>Plant Communications</i>. 2024;5(1). doi:<a href="https://doi.org/10.1016/j.xplc.2023.100669">10.1016/j.xplc.2023.100669</a>
  apa: Tang, H., Lu, K., Zhang, Y., Cheng, Y., Tu, S., &#38; Friml, J. (2024). Divergence
    of trafficking and polarization mechanisms for PIN auxin transporters during land
    plant evolution. <i>Plant Communications</i>. Elsevier. <a href="https://doi.org/10.1016/j.xplc.2023.100669">https://doi.org/10.1016/j.xplc.2023.100669</a>
  chicago: Tang, Han, KJ Lu, Y Zhang, YL Cheng, SL Tu, and Jiří Friml. “Divergence
    of Trafficking and Polarization Mechanisms for PIN Auxin Transporters during Land
    Plant Evolution.” <i>Plant Communications</i>. Elsevier, 2024. <a href="https://doi.org/10.1016/j.xplc.2023.100669">https://doi.org/10.1016/j.xplc.2023.100669</a>.
  ieee: H. Tang, K. Lu, Y. Zhang, Y. Cheng, S. Tu, and J. Friml, “Divergence of trafficking
    and polarization mechanisms for PIN auxin transporters during land plant evolution,”
    <i>Plant Communications</i>, vol. 5, no. 1. Elsevier, 2024.
  ista: Tang H, Lu K, Zhang Y, Cheng Y, Tu S, Friml J. 2024. Divergence of trafficking
    and polarization mechanisms for PIN auxin transporters during land plant evolution.
    Plant Communications. 5(1), 100669.
  mla: Tang, Han, et al. “Divergence of Trafficking and Polarization Mechanisms for
    PIN Auxin Transporters during Land Plant Evolution.” <i>Plant Communications</i>,
    vol. 5, no. 1, 100669, Elsevier, 2024, doi:<a href="https://doi.org/10.1016/j.xplc.2023.100669">10.1016/j.xplc.2023.100669</a>.
  short: H. Tang, K. Lu, Y. Zhang, Y. Cheng, S. Tu, J. Friml, Plant Communications
    5 (2024).
date_created: 2023-09-01T11:32:02Z
date_published: 2024-01-08T00:00:00Z
date_updated: 2025-07-02T12:51:02Z
day: '08'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1016/j.xplc.2023.100669
ec_funded: 1
external_id:
  pmid:
  - '37528584'
file:
- access_level: open_access
  checksum: edbc44c6d4a394d2bf70f92fdbb08f0a
  content_type: application/pdf
  creator: dernst
  date_created: 2024-01-30T12:59:57Z
  date_updated: 2024-01-30T12:59:57Z
  file_id: '14911'
  file_name: 2023_PlantCommunications_Tang.pdf
  file_size: 2825565
  relation: main_file
  success: 1
file_date_updated: 2024-01-30T12:59:57Z
has_accepted_license: '1'
intvolume: '         5'
issue: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 261099A6-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '742985'
  name: Tracing Evolution of Auxin Transport and Polarity in Plants
publication: Plant Communications
publication_identifier:
  issn:
  - 2590-3462
  issnl:
  - 1234-4567
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Divergence of trafficking and polarization mechanisms for PIN auxin transporters
  during land plant evolution
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2024'
...
---
_id: '14479'
abstract:
- lang: eng
  text: 'In animals, parasitic infections impose significant fitness costs.1,2,3,4,5,6
    Infected animals can alter their feeding behavior to resist infection,7,8,9,10,11,12
    but parasites can manipulate animal foraging behavior to their own benefits.13,14,15,16
    How nutrition influences host-parasite interactions is not well understood, as
    studies have mainly focused on the host and less on the parasite.9,12,17,18,19,20,21,22,23
    We used the nutritional geometry framework24 to investigate the role of amino
    acids (AA) and carbohydrates (C) in a host-parasite system: the Argentine ant,
    Linepithema humile, and the entomopathogenic fungus, Metarhizium brunneum. First,
    using 18 diets varying in AA:C composition, we established that the fungus performed
    best on the high-amino-acid diet 1:4. Second, we found that the fungus reached
    this optimal diet when given various diet pairings, revealing its ability to cope
    with nutritional challenges. Third, we showed that the optimal fungal diet reduced
    the lifespan of healthy ants when compared with a high-carbohydrate diet but had
    no effect on infected ants. Fourth, we revealed that infected ant colonies, given
    a choice between the optimal fungal diet and a high-carbohydrate diet, chose the
    optimal fungal diet, whereas healthy colonies avoided it. Lastly, by disentangling
    fungal infection from host immune response, we demonstrated that infected ants
    foraged on the optimal fungal diet in response to immune activation and not as
    a result of parasite manipulation. Therefore, we revealed that infected ant colonies
    chose a diet that is costly for survival in the long term but beneficial in the
    short term—a form of collective self-medication.'
acknowledgement: We are sincerely grateful to the referees for their valuable comments
  and suggestions, which helped us to improve the paper. We are thankful to Jorgen
  Eilenberg and Nicolai V. Meyling for the fungal strain, to Simon Tragust, Abel Bernadou,
  and Brian Lazarro for insightful discussions, to Iago Sanmartín-Villar, Léa Briard,
  Céline Maitrel, and Nolwenn Rissen for their help with the experiments. Furthermore,
  we thank Anna V. Grasse for help with the immune gene expression analyses. We thank
  Sergio Ibarra for creating the graphical abstract. E.C. was supported by a Fyssen
  Foundation grant and the Alexander von Humboldt Foundation. A.D. was supported by
  the CNRS.
article_processing_charge: No
article_type: original
author:
- first_name: Eniko
  full_name: Csata, Eniko
  last_name: Csata
- first_name: Alfonso
  full_name: Perez-Escudero, Alfonso
  last_name: Perez-Escudero
- first_name: Emmanuel
  full_name: Laury, Emmanuel
  last_name: Laury
- first_name: Hanna
  full_name: Leitner, Hanna
  id: 8fc5c6f6-5903-11ec-abad-c83f046253e7
  last_name: Leitner
- first_name: Gerard
  full_name: Latil, Gerard
  last_name: Latil
- first_name: Juerge
  full_name: Heinze, Juerge
  last_name: Heinze
- first_name: Stephen
  full_name: Simpson, Stephen
  last_name: Simpson
- first_name: Sylvia
  full_name: Cremer, Sylvia
  id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
  last_name: Cremer
  orcid: 0000-0002-2193-3868
- first_name: Audrey
  full_name: Dussutour, Audrey
  last_name: Dussutour
citation:
  ama: Csata E, Perez-Escudero A, Laury E, et al. Fungal infection alters collective
    nutritional intake of ant colonies. <i>Current Biology</i>. 2024;34(4):902-909.e6.
    doi:<a href="https://doi.org/10.1016/j.cub.2024.01.017">10.1016/j.cub.2024.01.017</a>
  apa: Csata, E., Perez-Escudero, A., Laury, E., Leitner, H., Latil, G., Heinze, J.,
    … Dussutour, A. (2024). Fungal infection alters collective nutritional intake
    of ant colonies. <i>Current Biology</i>. Elsevier. <a href="https://doi.org/10.1016/j.cub.2024.01.017">https://doi.org/10.1016/j.cub.2024.01.017</a>
  chicago: Csata, Eniko, Alfonso Perez-Escudero, Emmanuel Laury, Hanna Leitner, Gerard
    Latil, Juerge Heinze, Stephen Simpson, Sylvia Cremer, and Audrey Dussutour. “Fungal
    Infection Alters Collective Nutritional Intake of Ant Colonies.” <i>Current Biology</i>.
    Elsevier, 2024. <a href="https://doi.org/10.1016/j.cub.2024.01.017">https://doi.org/10.1016/j.cub.2024.01.017</a>.
  ieee: E. Csata <i>et al.</i>, “Fungal infection alters collective nutritional intake
    of ant colonies,” <i>Current Biology</i>, vol. 34, no. 4. Elsevier, p. 902–909.e6,
    2024.
  ista: Csata E, Perez-Escudero A, Laury E, Leitner H, Latil G, Heinze J, Simpson
    S, Cremer S, Dussutour A. 2024. Fungal infection alters collective nutritional
    intake of ant colonies. Current Biology. 34(4), 902–909.e6.
  mla: Csata, Eniko, et al. “Fungal Infection Alters Collective Nutritional Intake
    of Ant Colonies.” <i>Current Biology</i>, vol. 34, no. 4, Elsevier, 2024, p. 902–909.e6,
    doi:<a href="https://doi.org/10.1016/j.cub.2024.01.017">10.1016/j.cub.2024.01.017</a>.
  short: E. Csata, A. Perez-Escudero, E. Laury, H. Leitner, G. Latil, J. Heinze, S.
    Simpson, S. Cremer, A. Dussutour, Current Biology 34 (2024) 902–909.e6.
dataavailabilitystatement: no DAS
date_created: 2023-10-31T13:30:20Z
date_published: 2024-02-26T00:00:00Z
date_updated: 2026-03-18T11:15:21Z
day: '26'
department:
- _id: SyCr
doi: 10.1016/j.cub.2024.01.017
external_id:
  pmid:
  - '38307022'
intvolume: '        34'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1101/2023.10.26.564092
month: '02'
oa: 1
oa_version: Preprint
page: 902-909.e6
pmid: 1
publication: Current Biology
publication_identifier:
  eissn:
  - 1879-0445
  issn:
  - 0960-9822
  issnl:
  - 1234-5678
publication_status: published
publisher: Elsevier
quality_controlled: '1'
researchdata_availability: unclear
scopus_import: '1'
status: public
supplementarymaterial: yes
title: Fungal infection alters collective nutritional intake of ant colonies
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 34
year: '2024'
...
---
_id: '14705'
abstract:
- lang: eng
  text: Since the commercialization of brine shrimp (genus Artemia) in the 1950s,
    this lineage, and in particular the model species Artemia franciscana, has been
    the subject of extensive research. However, our understanding of the genetic mechanisms
    underlying various aspects of their reproductive biology, including sex determination,
    are still lacking. This is partly due to the scarcity of genomic resources for
    Artemia species and crustaceans in general. Here, we present a chromosome-level
    genome assembly of Artemia franciscana (Kellogg 1906), from the Great Salt Lake,
    USA. The genome is 1GB, and the majority of the genome (81%) is scaffolded into
    21 linkage groups using a previously published high-density linkage map. We performed
    coverage and FST analyses using male and female genomic and transcriptomic reads
    to quantify the extent of differentiation between the Z and W chromosomes. Additionally,
    we quantified the expression levels in male and female heads and gonads and found
    further evidence for dosage compensation in this species.
article_processing_charge: No
author:
- first_name: Marwan N
  full_name: Elkrewi, Marwan N
  id: 0B46FACA-A8E1-11E9-9BD3-79D1E5697425
  last_name: Elkrewi
  orcid: 0000-0002-5328-7231
citation:
  ama: Elkrewi MN. Data from “Chromosome-level assembly of Artemia franciscana sheds
    light on sex-chromosome differentiation.” 2024. doi:<a href="https://doi.org/10.15479/AT:ISTA:14705">10.15479/AT:ISTA:14705</a>
  apa: Elkrewi, M. N. (2024). Data from “Chromosome-level assembly of Artemia franciscana
    sheds light on sex-chromosome differentiation.” Institute of Science and Technology
    Austria. <a href="https://doi.org/10.15479/AT:ISTA:14705">https://doi.org/10.15479/AT:ISTA:14705</a>
  chicago: Elkrewi, Marwan N. “Data from ‘Chromosome-Level Assembly of Artemia Franciscana
    Sheds Light on Sex-Chromosome Differentiation.’” Institute of Science and Technology
    Austria, 2024. <a href="https://doi.org/10.15479/AT:ISTA:14705">https://doi.org/10.15479/AT:ISTA:14705</a>.
  ieee: M. N. Elkrewi, “Data from ‘Chromosome-level assembly of Artemia franciscana
    sheds light on sex-chromosome differentiation.’” Institute of Science and Technology
    Austria, 2024.
  ista: Elkrewi MN. 2024. Data from ‘Chromosome-level assembly of Artemia franciscana
    sheds light on sex-chromosome differentiation’, Institute of Science and Technology
    Austria, <a href="https://doi.org/10.15479/AT:ISTA:14705">10.15479/AT:ISTA:14705</a>.
  mla: Elkrewi, Marwan N. <i>Data from “Chromosome-Level Assembly of Artemia Franciscana
    Sheds Light on Sex-Chromosome Differentiation.”</i> Institute of Science and Technology
    Austria, 2024, doi:<a href="https://doi.org/10.15479/AT:ISTA:14705">10.15479/AT:ISTA:14705</a>.
  short: M.N. Elkrewi, (2024).
contributor:
- contributor_type: researcher
  first_name: Vincent K
  id: 57854184-AAE0-11E9-8D04-98D6E5697425
  last_name: Bett
- contributor_type: project_member
  first_name: Ariana
  id: 2A0848E2-F248-11E8-B48F-1D18A9856A87
  last_name: Macon
- contributor_type: supervisor
  first_name: Beatriz
  id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
  last_name: Vicoso
  orcid: 0000-0002-4579-8306
- contributor_type: researcher
  first_name: Marwan N
  id: 0B46FACA-A8E1-11E9-9BD3-79D1E5697425
  last_name: Elkrewi
  orcid: 0000-0002-5328-7231
date_created: 2023-12-22T13:40:48Z
date_published: 2024-01-02T00:00:00Z
date_updated: 2026-05-18T12:46:40Z
day: '02'
ddc:
- '576'
department:
- _id: GradSch
- _id: BeVi
doi: 10.15479/AT:ISTA:14705
has_accepted_license: '1'
keyword:
- sex chromosome evolution
- genome assembly
- dosage compensation
month: '01'
oa_version: Published Version
project:
- _id: 34ae1506-11ca-11ed-8bc3-c14f4c474396
  grant_number: F8810
  name: The highjacking of meiosis for asexual reproduction
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '15009'
    relation: used_in_publication
    status: public
retracted: '1'
status: public
title: Data from "Chromosome-level assembly of Artemia franciscana sheds light on
  sex-chromosome differentiation"
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: research_data
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2024'
...
---
_id: '14711'
abstract:
- lang: eng
  text: "In nature, different species find their niche in a range of environments,
    each with its unique characteristics. While some thrive in uniform (homogeneous)
    landscapes where environmental conditions stay relatively consistent across space,
    others traverse the complexities of spatially heterogeneous terrains. Comprehending
    how species are distributed and how they interact within these landscapes holds
    the key to gaining insights into their evolutionary dynamics while also informing
    conservation and management strategies.\r\n\r\nFor species inhabiting heterogeneous
    landscapes, when the rate of dispersal is low compared to spatial fluctuations
    in selection pressure, localized adaptations may emerge. Such adaptation in response
    to varying selection strengths plays an important role in the persistence of populations
    in our rapidly changing world. Hence, species in nature are continuously in a
    struggle to adapt to local environmental conditions, to ensure their continued
    survival. Natural populations can often adapt in time scales short enough for
    evolutionary changes to influence ecological dynamics and vice versa, thereby
    creating a feedback between evolution and demography. The analysis of this feedback
    and the relative contributions of gene flow, demography, drift, and natural selection
    to genetic variation and differentiation has remained a recurring theme in evolutionary
    biology. Nevertheless, the effective role of these forces in maintaining variation
    and shaping patterns of diversity is not fully understood. Even in homogeneous
    environments devoid of local adaptations, such understanding remains elusive.
    Understanding this feedback is crucial, for example in determining the conditions
    under which extinction risk can be mitigated in peripheral populations subject
    to deleterious mutation accumulation at the edges of species’ ranges\r\nas well
    as in highly fragmented populations.\r\n\r\nIn this thesis we explore both uniform
    and spatially heterogeneous metapopulations, investigating and providing theoretical
    insights into the dynamics of local adaptation in the latter and examining the
    dynamics of load and extinction as well as the impact of joint ecological and
    evolutionary (eco-evolutionary) dynamics in the former. The thesis is divided
    into 5 chapters.\r\n\r\nChapter 1 provides a general introduction into the subject
    matter, clarifying concepts and ideas used throughout the thesis. In chapter 2,
    we explore how fast a species distributed across a heterogeneous landscape adapts
    to changing conditions marked by alterations in carrying capacity, selection pressure,
    and migration rate.\r\n\r\nIn chapter 3, we investigate how migration selection
    and drift influences adaptation and the maintenance of variation in a metapopulation
    with three habitats, an extension of previous models of adaptation in two habitats.
    We further develop analytical approximations for the critical threshold required
    for polymorphism to persist.\r\n\r\nThe focus of chapter 4 of the thesis is on
    understanding the interplay between ecology and evolution as coupled processes.
    We investigate how eco-evolutionary feedback between migration, selection, drift,
    and demography influences eco-evolutionary outcomes in marginal populations subject
    to deleterious mutation accumulation. Using simulations as well as theoretical
    approximations of the coupled dynamics of population size and allele frequency,
    we analyze how gene flow from a large mainland source influences genetic load
    and population size on an island (i.e., in a marginal population) under genetically
    realistic assumptions. Analyses of this sort are important because small isolated
    populations, are repeatedly affected by complex interactions between ecological
    and evolutionary processes, which can lead to their death. Understanding these
    interactions can therefore provide an insight into the conditions under which
    extinction risk can be mitigated in peripheral populations thus, contributing
    to conservation and restoration efforts.\r\n\r\nChapter 5 extends the analysis
    in chapter 4 to consider the dynamics of load (due to deleterious mutation accumulation)
    and extinction risk in a metapopulation. We explore the role of gene flow, selection,
    and dominance on load and extinction risk and further pinpoint critical thresholds
    required for metapopulation persistence.\r\n\r\nOverall this research contributes
    to our understanding of ecological and evolutionary mechanisms that shape species’
    persistence in fragmented landscapes, a crucial foundation for successful conservation
    efforts and biodiversity management."
acknowledged_ssus:
- _id: SSU
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Oluwafunmilola O
  full_name: Olusanya, Oluwafunmilola O
  id: 41AD96DC-F248-11E8-B48F-1D18A9856A87
  last_name: Olusanya
  orcid: 0000-0003-1971-8314
date_created: 2023-12-26T22:49:53Z
date_published: 2024-01-19T00:00:00Z
date_updated: 2025-05-26T09:05:10Z
day: '19'
ddc:
- '576'
degree_awarded: MS
department:
- _id: NiBa
- _id: GradSch
doi: 10.15479/at:ista:14711
ec_funded: 1
file:
- access_level: closed
  checksum: de179b1c6758f182ff0c70d8b38c1501
  content_type: application/zip
  creator: oolusany
  date_created: 2024-01-03T18:30:13Z
  date_updated: 2024-01-03T18:30:13Z
  file_id: '14730'
  file_name: FinalSubmission_Thesis_OLUSANYA.zip
  file_size: 16986244
  relation: source_file
- access_level: open_access
  checksum: 0e331585e3cd4823320aab4e69e64ccf
  content_type: application/pdf
  creator: oolusany
  date_created: 2024-01-03T18:31:34Z
  date_updated: 2024-01-03T18:31:34Z
  file_id: '14731'
  file_name: FinalSubmission2_Thesis_OLUSANYA.pdf
  file_size: 6460403
  relation: main_file
  success: 1
file_date_updated: 2024-01-03T18:31:34Z
has_accepted_license: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: '183'
project:
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
- _id: c08d3278-5a5b-11eb-8a69-fdb09b55f4b8
  grant_number: P32896
  name: Causes and consequences of population fragmentation
- _id: 34c872fe-11ca-11ed-8bc3-8534b82131e6
  grant_number: '26380'
  name: Polygenic Adaptation in a Metapopulation
publication_identifier:
  issn:
  - 2663 - 337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '10658'
    relation: part_of_dissertation
    status: public
  - id: '10787'
    relation: part_of_dissertation
    status: public
  - id: '14732'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Jitka
  full_name: Polechova, Jitka
  last_name: Polechova
- first_name: Himani
  full_name: Sachdeva, Himani
  last_name: Sachdeva
title: Local adaptation, genetic load and extinction in metapopulations
tmp:
  image: /images/cc_by_nc_sa.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC
    BY-NC-SA 4.0)
  short: CC BY-NC-SA (4.0)
type: dissertation
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2024'
...
---
_id: '14769'
abstract:
- lang: eng
  text: 'For a set of points in Rd, the Euclidean k-means problems consists of finding
    k centers such that the sum of distances squared from each data point to its closest
    center is minimized. Coresets are one the main tools developed recently to solve
    this problem in a big data context. They allow to compress the initial dataset
    while preserving its structure: running any algorithm on the coreset provides
    a guarantee almost equivalent to running it on the full data. In this work, we
    study coresets in a fully-dynamic setting: points are added and deleted with the
    goal to efficiently maintain a coreset with which a k-means solution can be computed.
    Based on an algorithm from Henzinger and Kale [ESA''20], we present an efficient
    and practical implementation of a fully dynamic coreset algorithm, that improves
    the running time by up to a factor of 20 compared to our non-optimized implementation
    of the algorithm by Henzinger and Kale, without sacrificing more than 7% on the
    quality of the k-means solution.'
acknowledgement: This   project   has   received   funding   from   the   Euro-pean  Research  Council  (ERC)  under  the  EuropeanUnion’s  Horizon  2020  research  and  innovation  programme  (Grant  agreement  No.   101019564  “The  De-sign  of  Modern  Fully  Dynamic  Data  Structures  (Mo-DynStruct)”  and  the  Austrian  Science  Fund  (FWF)project
  Z 422-N, project “Static and Dynamic Hierar-chical  Graph  Decompositions”,  I  5982-N,  and  project“Fast  Algorithms  for  a  Reactive  Network  Layer  (Re-actNet)”,
  P 33775-N, with additional funding from thenetidee SCIENCE Stiftung, 2020–2024.D.  Sauplic  has  received  funding  from  the  Euro-pean  Union’s  Horizon  2020  research  and  innovation
  programme under the Marie Sklodowska-Curie    grant    agreementNo 101034413.
article_processing_charge: No
arxiv: 1
author:
- first_name: Monika H
  full_name: Henzinger, Monika H
  id: 540c9bbd-f2de-11ec-812d-d04a5be85630
  last_name: Henzinger
  orcid: 0000-0002-5008-6530
- first_name: David
  full_name: Saulpic, David
  id: f8e48cf0-b0ff-11ed-b0e9-b4c35598f964
  last_name: Saulpic
- first_name: Leonhard
  full_name: Sidl, Leonhard
  id: 8b563fd0-b441-11ee-9101-a3891c61efa6
  last_name: Sidl
citation:
  ama: 'Henzinger MH, Saulpic D, Sidl L. Experimental evaluation of fully dynamic
    k-means via coresets. In: <i>2024 Proceedings of the Symposium on Algorithm Engineering
    and Experiments</i>. Society for Industrial &#38; Applied Mathematics; 2024:220-233.
    doi:<a href="https://doi.org/10.1137/1.9781611977929.17">10.1137/1.9781611977929.17</a>'
  apa: 'Henzinger, M. H., Saulpic, D., &#38; Sidl, L. (2024). Experimental evaluation
    of fully dynamic k-means via coresets. In <i>2024 Proceedings of the Symposium
    on Algorithm Engineering and Experiments</i> (pp. 220–233). Alexandria, VA, United
    States: Society for Industrial &#38; Applied Mathematics. <a href="https://doi.org/10.1137/1.9781611977929.17">https://doi.org/10.1137/1.9781611977929.17</a>'
  chicago: Henzinger, Monika H, David Saulpic, and Leonhard Sidl. “Experimental Evaluation
    of Fully Dynamic K-Means via Coresets.” In <i>2024 Proceedings of the Symposium
    on Algorithm Engineering and Experiments</i>, 220–33. Society for Industrial &#38;
    Applied Mathematics, 2024. <a href="https://doi.org/10.1137/1.9781611977929.17">https://doi.org/10.1137/1.9781611977929.17</a>.
  ieee: M. H. Henzinger, D. Saulpic, and L. Sidl, “Experimental evaluation of fully
    dynamic k-means via coresets,” in <i>2024 Proceedings of the Symposium on Algorithm
    Engineering and Experiments</i>, Alexandria, VA, United States, 2024, pp. 220–233.
  ista: 'Henzinger MH, Saulpic D, Sidl L. 2024. Experimental evaluation of fully dynamic
    k-means via coresets. 2024 Proceedings of the Symposium on Algorithm Engineering
    and Experiments. ALENEX: Workshop on Algorithm Engineering and Experiments, 220–233.'
  mla: Henzinger, Monika H., et al. “Experimental Evaluation of Fully Dynamic K-Means
    via Coresets.” <i>2024 Proceedings of the Symposium on Algorithm Engineering and
    Experiments</i>, Society for Industrial &#38; Applied Mathematics, 2024, pp. 220–33,
    doi:<a href="https://doi.org/10.1137/1.9781611977929.17">10.1137/1.9781611977929.17</a>.
  short: M.H. Henzinger, D. Saulpic, L. Sidl, in:, 2024 Proceedings of the Symposium
    on Algorithm Engineering and Experiments, Society for Industrial &#38; Applied
    Mathematics, 2024, pp. 220–233.
conference:
  end_date: 2024-01-08
  location: Alexandria, VA, United States
  name: 'ALENEX: Workshop on Algorithm Engineering and Experiments'
  start_date: 2024-01-07
date_created: 2024-01-09T16:22:47Z
date_published: 2024-01-04T00:00:00Z
date_updated: 2025-07-15T12:51:52Z
day: '04'
department:
- _id: MoHe
doi: 10.1137/1.9781611977929.17
ec_funded: 1
external_id:
  arxiv:
  - '2310.18034'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2310.18034
month: '01'
oa: 1
oa_version: Preprint
page: 220-233
project:
- _id: bd9ca328-d553-11ed-ba76-dc4f890cfe62
  call_identifier: H2020
  grant_number: '101019564'
  name: The design and evaluation of modern fully dynamic data structures
- _id: 34def286-11ca-11ed-8bc3-da5948e1613c
  grant_number: Z00422
  name: Wittgenstein Award - Monika Henzinger
- _id: bda196b2-d553-11ed-ba76-8e8ee6c21103
  grant_number: I05982
  name: Static and Dynamic Hierarchical Graph Decompositions
- _id: bd9e3a2e-d553-11ed-ba76-8aa684ce17fe
  grant_number: 'P33775 '
  name: Fast Algorithms for a Reactive Network Layer
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
  call_identifier: H2020
  grant_number: '101034413'
  name: 'IST-BRIDGE: International postdoctoral program'
publication: 2024 Proceedings of the Symposium on Algorithm Engineering and Experiments
publication_identifier:
  eisbn:
  - '9781611977929'
publication_status: published
publisher: Society for Industrial & Applied Mathematics
quality_controlled: '1'
scopus_import: '1'
status: public
title: Experimental evaluation of fully dynamic k-means via coresets
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2024'
...
---
_id: '12158'
abstract:
- lang: eng
  text: 'Post-translational histone modifications modulate chromatin activity to affect
    gene expression. How chromatin states underlie lineage choice in single cells
    is relatively unexplored. We develop sort-assisted single-cell chromatin immunocleavage
    (sortChIC) and map active (H3K4me1 and H3K4me3) and repressive (H3K27me3 and H3K9me3)
    histone modifications in the mouse bone marrow. During differentiation, hematopoietic
    stem and progenitor cells (HSPCs) acquire active chromatin states mediated by
    cell-type-specifying transcription factors, which are unique for each lineage.
    By contrast, most alterations in repressive marks during differentiation occur
    independent of the final cell type. Chromatin trajectory analysis shows that lineage
    choice at the chromatin level occurs at the progenitor stage. Joint profiling
    of H3K4me1 and H3K9me3 demonstrates that cell types within the myeloid lineage
    have distinct active chromatin but share similar myeloid-specific heterochromatin
    states. This implies a hierarchical regulation of chromatin during hematopoiesis:
    heterochromatin dynamics distinguish differentiation trajectories and lineages,
    while euchromatin dynamics reflect cell types within lineages.'
acknowledgement: We thank A. Giladi for sharing mRNA abundance tables of cell types
  together with J. van den Berg for critical reading of the manuscript. We thank M.
  Bartosovic for sharing method comparison data. pK19pA-MN was a gift from Ulrich
  Laemmli (Addgene plasmid 86973, http://n2t.net/addgene:86973; RRID:Addgene_86973).
  Figure 8 is adopted from Hematopoiesis (human) diagram by A. Rad and M. Häggström
  under CC-BY-SA 3.0 license. This work was supported by European Research Council
  Advanced under grant ERC-AdG 742225-IntScOmics and Nederlandse Organisatie voor
  Wetenschappelijk Onderzoek (NWO) TOP award NWO-CW 714.016.001. The SNF (P2BSP3-174991),
  HFSP (LT000209/2018-L) and Marie Skłodowska-Curie Actions (798573) supported P.Z.
  The SNF (P2ELP3_184488) and HFSP (LT000097/2019-L) supported J.Y. and the EMBO LTF
  (ALTF 1197–2019) supported V.B. This work is part of the Oncode Institute, which
  is partly financed by the Dutch Cancer Society. The funders had no role in study
  design, data collection and analysis, decision to publish or preparation of the
  manuscript.
article_processing_charge: No
article_type: review
author:
- first_name: Peter
  full_name: Zeller, Peter
  last_name: Zeller
- first_name: Jake
  full_name: Yeung, Jake
  id: 123012b2-db30-11eb-b4d8-a35840c0551b
  last_name: Yeung
  orcid: 0000-0003-1732-1559
- first_name: Helena
  full_name: Viñas Gaza, Helena
  last_name: Viñas Gaza
- first_name: Buys Anton
  full_name: de Barbanson, Buys Anton
  last_name: de Barbanson
- first_name: Vivek
  full_name: Bhardwaj, Vivek
  last_name: Bhardwaj
- first_name: Maria
  full_name: Florescu, Maria
  last_name: Florescu
- first_name: Reinier
  full_name: van der Linden, Reinier
  last_name: van der Linden
- first_name: Alexander
  full_name: van Oudenaarden, Alexander
  last_name: van Oudenaarden
citation:
  ama: Zeller P, Yeung J, Viñas Gaza H, et al. Single-cell sortChIC identifies hierarchical
    chromatin dynamics during hematopoiesis. <i>Nature Genetics</i>. 2023;55:333-345.
    doi:<a href="https://doi.org/10.1038/s41588-022-01260-3">10.1038/s41588-022-01260-3</a>
  apa: Zeller, P., Yeung, J., Viñas Gaza, H., de Barbanson, B. A., Bhardwaj, V., Florescu,
    M., … van Oudenaarden, A. (2023). Single-cell sortChIC identifies hierarchical
    chromatin dynamics during hematopoiesis. <i>Nature Genetics</i>. Springer Nature.
    <a href="https://doi.org/10.1038/s41588-022-01260-3">https://doi.org/10.1038/s41588-022-01260-3</a>
  chicago: Zeller, Peter, Jake Yeung, Helena Viñas Gaza, Buys Anton de Barbanson,
    Vivek Bhardwaj, Maria Florescu, Reinier van der Linden, and Alexander van Oudenaarden.
    “Single-Cell SortChIC Identifies Hierarchical Chromatin Dynamics during Hematopoiesis.”
    <i>Nature Genetics</i>. Springer Nature, 2023. <a href="https://doi.org/10.1038/s41588-022-01260-3">https://doi.org/10.1038/s41588-022-01260-3</a>.
  ieee: P. Zeller <i>et al.</i>, “Single-cell sortChIC identifies hierarchical chromatin
    dynamics during hematopoiesis,” <i>Nature Genetics</i>, vol. 55. Springer Nature,
    pp. 333–345, 2023.
  ista: Zeller P, Yeung J, Viñas Gaza H, de Barbanson BA, Bhardwaj V, Florescu M,
    van der Linden R, van Oudenaarden A. 2023. Single-cell sortChIC identifies hierarchical
    chromatin dynamics during hematopoiesis. Nature Genetics. 55, 333–345.
  mla: Zeller, Peter, et al. “Single-Cell SortChIC Identifies Hierarchical Chromatin
    Dynamics during Hematopoiesis.” <i>Nature Genetics</i>, vol. 55, Springer Nature,
    2023, pp. 333–45, doi:<a href="https://doi.org/10.1038/s41588-022-01260-3">10.1038/s41588-022-01260-3</a>.
  short: P. Zeller, J. Yeung, H. Viñas Gaza, B.A. de Barbanson, V. Bhardwaj, M. Florescu,
    R. van der Linden, A. van Oudenaarden, Nature Genetics 55 (2023) 333–345.
date_created: 2023-01-12T12:09:09Z
date_published: 2023-02-01T00:00:00Z
date_updated: 2023-02-27T07:48:24Z
day: '01'
ddc:
- '570'
- '000'
department:
- _id: ScienComp
doi: 10.1038/s41588-022-01260-3
file:
- access_level: open_access
  checksum: 6fdb8e34fbeea63edd0f2c6c2cc5823e
  content_type: application/pdf
  creator: dernst
  date_created: 2023-02-27T07:46:45Z
  date_updated: 2023-02-27T07:46:45Z
  file_id: '12688'
  file_name: 2023_NatureGenetics_Zeller.pdf
  file_size: 21484855
  relation: main_file
  success: 1
file_date_updated: 2023-02-27T07:46:45Z
has_accepted_license: '1'
intvolume: '        55'
keyword:
- Genetics
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
page: 333-345
publication: Nature Genetics
publication_identifier:
  eissn:
  - 1546-1718
  issn:
  - 1061-4036
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Single-cell sortChIC identifies hierarchical chromatin dynamics during hematopoiesis
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 55
year: '2023'
...
---
_id: '12159'
abstract:
- lang: eng
  text: The term “haplotype block” is commonly used in the developing field of haplotype-based
    inference methods. We argue that the term should be defined based on the structure
    of the Ancestral Recombination Graph (ARG), which contains complete information
    on the ancestry of a sample. We use simulated examples to demonstrate key features
    of the relationship between haplotype blocks and ancestral structure, emphasizing
    the stochasticity of the processes that generate them. Even the simplest cases
    of neutrality or of a “hard” selective sweep produce a rich structure, often missed
    by commonly used statistics. We highlight a number of novel methods for inferring
    haplotype structure, based on the full ARG, or on a sequence of trees, and illustrate
    how they can be used to define haplotype blocks using an empirical data set. While
    the advent of new, computationally efficient methods makes it possible to apply
    these concepts broadly, they (and additional new methods) could benefit from adding
    features to explore haplotype blocks, as we define them. Understanding and applying
    the concept of the haplotype block will be essential to fully exploit long and
    linked-read sequencing technologies.
acknowledgement: 'We thank the Barton group for useful discussion and feedback during
  the writing of this article. Comments from Roger Butlin, Molly Schumer''s Group,
  the tskit development team, editors and three reviewers greatly improved the manuscript.
  Funding was provided by SCAS (Natural Sciences Programme, Knut and Alice Wallenberg
  Foundation), an FWF Wittgenstein grant (PT1001Z211), an FWF standalone grant (grant
  P 32166), and an ERC Advanced Grant. YFC was supported by the Max Planck Society
  and an ERC Proof of Concept Grant #101069216 (HAPLOTAGGING).'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Daria
  full_name: Shipilina, Daria
  id: 428A94B0-F248-11E8-B48F-1D18A9856A87
  last_name: Shipilina
  orcid: 0000-0002-1145-9226
- first_name: Arka
  full_name: Pal, Arka
  id: 6AAB2240-CA9A-11E9-9C1A-D9D1E5697425
  last_name: Pal
  orcid: 0000-0002-4530-8469
- first_name: Sean
  full_name: Stankowski, Sean
  id: 43161670-5719-11EA-8025-FABC3DDC885E
  last_name: Stankowski
- first_name: Yingguang Frank
  full_name: Chan, Yingguang Frank
  last_name: Chan
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
citation:
  ama: Shipilina D, Pal A, Stankowski S, Chan YF, Barton NH. On the origin and structure
    of haplotype blocks. <i>Molecular Ecology</i>. 2023;32(6):1441-1457. doi:<a href="https://doi.org/10.1111/mec.16793">10.1111/mec.16793</a>
  apa: Shipilina, D., Pal, A., Stankowski, S., Chan, Y. F., &#38; Barton, N. H. (2023).
    On the origin and structure of haplotype blocks. <i>Molecular Ecology</i>. Wiley.
    <a href="https://doi.org/10.1111/mec.16793">https://doi.org/10.1111/mec.16793</a>
  chicago: Shipilina, Daria, Arka Pal, Sean Stankowski, Yingguang Frank Chan, and
    Nicholas H Barton. “On the Origin and Structure of Haplotype Blocks.” <i>Molecular
    Ecology</i>. Wiley, 2023. <a href="https://doi.org/10.1111/mec.16793">https://doi.org/10.1111/mec.16793</a>.
  ieee: D. Shipilina, A. Pal, S. Stankowski, Y. F. Chan, and N. H. Barton, “On the
    origin and structure of haplotype blocks,” <i>Molecular Ecology</i>, vol. 32,
    no. 6. Wiley, pp. 1441–1457, 2023.
  ista: Shipilina D, Pal A, Stankowski S, Chan YF, Barton NH. 2023. On the origin
    and structure of haplotype blocks. Molecular Ecology. 32(6), 1441–1457.
  mla: Shipilina, Daria, et al. “On the Origin and Structure of Haplotype Blocks.”
    <i>Molecular Ecology</i>, vol. 32, no. 6, Wiley, 2023, pp. 1441–57, doi:<a href="https://doi.org/10.1111/mec.16793">10.1111/mec.16793</a>.
  short: D. Shipilina, A. Pal, S. Stankowski, Y.F. Chan, N.H. Barton, Molecular Ecology
    32 (2023) 1441–1457.
date_created: 2023-01-12T12:09:17Z
date_published: 2023-03-01T00:00:00Z
date_updated: 2023-08-16T08:18:47Z
day: '01'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1111/mec.16793
external_id:
  isi:
  - '000900762000001'
  pmid:
  - '36433653'
file:
- access_level: open_access
  checksum: b10e0f8fa3dc4d72aaf77a557200978a
  content_type: application/pdf
  creator: dernst
  date_created: 2023-08-16T08:15:41Z
  date_updated: 2023-08-16T08:15:41Z
  file_id: '14062'
  file_name: 2023_MolecularEcology_Shipilina.pdf
  file_size: 7144607
  relation: main_file
  success: 1
file_date_updated: 2023-08-16T08:15:41Z
has_accepted_license: '1'
intvolume: '        32'
isi: 1
issue: '6'
keyword:
- Genetics
- Ecology
- Evolution
- Behavior and Systematics
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 1441-1457
pmid: 1
project:
- _id: 05959E1C-7A3F-11EA-A408-12923DDC885E
  grant_number: P32166
  name: The maintenance of alternative adaptive peaks in snapdragons
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: Z211
  name: The Wittgenstein Prize
- _id: bd6958e0-d553-11ed-ba76-86eba6a76c00
  grant_number: '101055327'
  name: Understanding the evolution of continuous genomes
publication: Molecular Ecology
publication_identifier:
  eissn:
  - 1365-294X
  issn:
  - 0962-1083
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: On the origin and structure of haplotype blocks
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 32
year: '2023'
...
---
_id: '12162'
abstract:
- lang: eng
  text: Homeostatic balance in the intestinal epithelium relies on a fast cellular
    turnover, which is coordinated by an intricate interplay between biochemical signalling,
    mechanical forces and organ geometry. We review recent modelling approaches that
    have been developed to understand different facets of this remarkable homeostatic
    equilibrium. Existing models offer different, albeit complementary, perspectives
    on the problem. First, biomechanical models aim to explain the local and global
    mechanical stresses driving cell renewal as well as tissue shape maintenance.
    Second, compartmental models provide insights into the conditions necessary to
    keep a constant flow of cells with well-defined ratios of cell types, and how
    perturbations can lead to an unbalance of relative compartment sizes. A third
    family of models address, at the cellular level, the nature and regulation of
    stem fate choices that are necessary to fuel cellular turnover. We also review
    how these different approaches are starting to be integrated together across scales,
    to provide quantitative predictions and new conceptual frameworks to think about
    the dynamics of cell renewal in complex tissues.
acknowledgement: "This work received funding from the ERC under the European Union’s
  Horizon 2020 research and innovation programme (grant agreement No. 851288 to E.H.).\r\nB.
  C-M wants to acknowledge the support of the field of excellence Complexity of Life,
  in Basic Research and Innovation of the University of Graz."
article_processing_charge: Yes (via OA deal)
article_type: review
author:
- first_name: Bernat
  full_name: Corominas-Murtra, Bernat
  id: 43BE2298-F248-11E8-B48F-1D18A9856A87
  last_name: Corominas-Murtra
  orcid: 0000-0001-9806-5643
- first_name: Edouard B
  full_name: Hannezo, Edouard B
  id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
  last_name: Hannezo
  orcid: 0000-0001-6005-1561
citation:
  ama: Corominas-Murtra B, Hannezo EB. Modelling the dynamics of mammalian gut homeostasis.
    <i>Seminars in Cell &#38; Developmental Biology</i>. 2023;150-151:58-65. doi:<a
    href="https://doi.org/10.1016/j.semcdb.2022.11.005">10.1016/j.semcdb.2022.11.005</a>
  apa: Corominas-Murtra, B., &#38; Hannezo, E. B. (2023). Modelling the dynamics of
    mammalian gut homeostasis. <i>Seminars in Cell &#38; Developmental Biology</i>.
    Elsevier. <a href="https://doi.org/10.1016/j.semcdb.2022.11.005">https://doi.org/10.1016/j.semcdb.2022.11.005</a>
  chicago: Corominas-Murtra, Bernat, and Edouard B Hannezo. “Modelling the Dynamics
    of Mammalian Gut Homeostasis.” <i>Seminars in Cell &#38; Developmental Biology</i>.
    Elsevier, 2023. <a href="https://doi.org/10.1016/j.semcdb.2022.11.005">https://doi.org/10.1016/j.semcdb.2022.11.005</a>.
  ieee: B. Corominas-Murtra and E. B. Hannezo, “Modelling the dynamics of mammalian
    gut homeostasis,” <i>Seminars in Cell &#38; Developmental Biology</i>, vol. 150–151.
    Elsevier, pp. 58–65, 2023.
  ista: Corominas-Murtra B, Hannezo EB. 2023. Modelling the dynamics of mammalian
    gut homeostasis. Seminars in Cell &#38; Developmental Biology. 150–151, 58–65.
  mla: Corominas-Murtra, Bernat, and Edouard B. Hannezo. “Modelling the Dynamics of
    Mammalian Gut Homeostasis.” <i>Seminars in Cell &#38; Developmental Biology</i>,
    vol. 150–151, Elsevier, 2023, pp. 58–65, doi:<a href="https://doi.org/10.1016/j.semcdb.2022.11.005">10.1016/j.semcdb.2022.11.005</a>.
  short: B. Corominas-Murtra, E.B. Hannezo, Seminars in Cell &#38; Developmental Biology
    150–151 (2023) 58–65.
date_created: 2023-01-12T12:09:47Z
date_published: 2023-12-02T00:00:00Z
date_updated: 2024-01-16T13:22:32Z
day: '02'
ddc:
- '570'
department:
- _id: EdHa
doi: 10.1016/j.semcdb.2022.11.005
ec_funded: 1
external_id:
  isi:
  - '001053522200001'
  pmid:
  - '36470715'
file:
- access_level: open_access
  checksum: c619887cf130f4649bf3035417186004
  content_type: application/pdf
  creator: dernst
  date_created: 2024-01-08T10:16:04Z
  date_updated: 2024-01-08T10:16:04Z
  file_id: '14741'
  file_name: 2023_SeminarsCellDevBiology_CorominasMurtra.pdf
  file_size: 1343750
  relation: main_file
  success: 1
file_date_updated: 2024-01-08T10:16:04Z
has_accepted_license: '1'
isi: 1
keyword:
- Cell Biology
- Developmental Biology
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 58-65
pmid: 1
project:
- _id: 05943252-7A3F-11EA-A408-12923DDC885E
  call_identifier: H2020
  grant_number: '851288'
  name: Design Principles of Branching Morphogenesis
publication: Seminars in Cell & Developmental Biology
publication_identifier:
  issn:
  - 1084-9521
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Modelling the dynamics of mammalian gut homeostasis
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 150-151
year: '2023'
...
---
_id: '12163'
abstract:
- lang: eng
  text: Small GTPases play essential roles in the organization of eukaryotic cells.
    In recent years, it has become clear that their intracellular functions result
    from intricate biochemical networks of the GTPase and their regulators that dynamically
    bind to a membrane surface. Due to the inherent complexities of their interactions,
    however, revealing the underlying mechanisms of action is often difficult to achieve
    from in vivo studies. This review summarizes in vitro reconstitution approaches
    developed to obtain a better mechanistic understanding of how small GTPase activities
    are regulated in space and time.
acknowledgement: The authors acknowledge support from IST Austria and helpful comments
  from the anonymous reviewers that helped to improve this manuscript. We apologize
  to the authors of primary literature and outstanding research not cited here due
  to space restraints.
article_processing_charge: Yes (via OA deal)
article_type: review
author:
- first_name: Martin
  full_name: Loose, Martin
  id: 462D4284-F248-11E8-B48F-1D18A9856A87
  last_name: Loose
  orcid: 0000-0001-7309-9724
- first_name: Albert
  full_name: Auer, Albert
  id: 3018E8C2-F248-11E8-B48F-1D18A9856A87
  last_name: Auer
  orcid: 0000-0002-3580-2906
- first_name: Gabriel
  full_name: Brognara, Gabriel
  id: D96FFDA0-A884-11E9-9968-DC26E6697425
  last_name: Brognara
- first_name: Hanifatul R
  full_name: Budiman, Hanifatul R
  id: 55380f95-15b2-11ec-abd3-aff8e230696b
  last_name: Budiman
- first_name: Lukasz M
  full_name: Kowalski, Lukasz M
  id: e3a512e2-4bbe-11eb-a68a-e3857a7844c2
  last_name: Kowalski
- first_name: Ivana
  full_name: Matijevic, Ivana
  id: 83c17ce3-15b2-11ec-abd3-f486545870bd
  last_name: Matijevic
citation:
  ama: Loose M, Auer A, Brognara G, Budiman HR, Kowalski LM, Matijevic I. In vitro
    reconstitution of small GTPase regulation. <i>FEBS Letters</i>. 2023;597(6):762-777.
    doi:<a href="https://doi.org/10.1002/1873-3468.14540">10.1002/1873-3468.14540</a>
  apa: Loose, M., Auer, A., Brognara, G., Budiman, H. R., Kowalski, L. M., &#38; Matijevic,
    I. (2023). In vitro reconstitution of small GTPase regulation. <i>FEBS Letters</i>.
    Wiley. <a href="https://doi.org/10.1002/1873-3468.14540">https://doi.org/10.1002/1873-3468.14540</a>
  chicago: Loose, Martin, Albert Auer, Gabriel Brognara, Hanifatul R Budiman, Lukasz
    M Kowalski, and Ivana Matijevic. “In Vitro Reconstitution of Small GTPase Regulation.”
    <i>FEBS Letters</i>. Wiley, 2023. <a href="https://doi.org/10.1002/1873-3468.14540">https://doi.org/10.1002/1873-3468.14540</a>.
  ieee: M. Loose, A. Auer, G. Brognara, H. R. Budiman, L. M. Kowalski, and I. Matijevic,
    “In vitro reconstitution of small GTPase regulation,” <i>FEBS Letters</i>, vol.
    597, no. 6. Wiley, pp. 762–777, 2023.
  ista: Loose M, Auer A, Brognara G, Budiman HR, Kowalski LM, Matijevic I. 2023. In
    vitro reconstitution of small GTPase regulation. FEBS Letters. 597(6), 762–777.
  mla: Loose, Martin, et al. “In Vitro Reconstitution of Small GTPase Regulation.”
    <i>FEBS Letters</i>, vol. 597, no. 6, Wiley, 2023, pp. 762–77, doi:<a href="https://doi.org/10.1002/1873-3468.14540">10.1002/1873-3468.14540</a>.
  short: M. Loose, A. Auer, G. Brognara, H.R. Budiman, L.M. Kowalski, I. Matijevic,
    FEBS Letters 597 (2023) 762–777.
date_created: 2023-01-12T12:09:58Z
date_published: 2023-03-01T00:00:00Z
date_updated: 2023-08-16T08:32:29Z
day: '01'
ddc:
- '570'
department:
- _id: MaLo
doi: 10.1002/1873-3468.14540
external_id:
  isi:
  - '000891573000001'
  pmid:
  - '36448231'
file:
- access_level: open_access
  checksum: 7492244d3f9c5faa1347ef03f6e5bc84
  content_type: application/pdf
  creator: dernst
  date_created: 2023-08-16T08:31:04Z
  date_updated: 2023-08-16T08:31:04Z
  file_id: '14063'
  file_name: 2023_FEBSLetters_Loose.pdf
  file_size: 3148143
  relation: main_file
  success: 1
file_date_updated: 2023-08-16T08:31:04Z
has_accepted_license: '1'
intvolume: '       597'
isi: 1
issue: '6'
keyword:
- Cell Biology
- Genetics
- Molecular Biology
- Biochemistry
- Structural Biology
- Biophysics
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '03'
oa: 1
oa_version: Published Version
page: 762-777
pmid: 1
publication: FEBS Letters
publication_identifier:
  eissn:
  - 1873-3468
  issn:
  - 0014-5793
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: In vitro reconstitution of small GTPase regulation
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 597
year: '2023'
...
---
_id: '12164'
abstract:
- lang: eng
  text: 'A shared-memory counter is a widely-used and well-studied concurrent object.
    It supports two operations: An Inc operation that increases its value by 1 and
    a Read operation that returns its current value. In Jayanti et al (SIAM J Comput,
    30(2), 2000), Jayanti, Tan and Toueg proved a linear lower bound on the worst-case
    step complexity of obstruction-free implementations, from read-write registers,
    of a large class of shared objects that includes counters. The lower bound leaves
    open the question of finding counter implementations with sub-linear amortized
    step complexity. In this work, we address this gap. We show that n-process, wait-free
    and linearizable counters can be implemented from read-write registers with O(log2n)
    amortized step complexity. This is the first counter algorithm from read-write
    registers that provides sub-linear amortized step complexity in executions of
    arbitrary length. Since a logarithmic lower bound on the amortized step complexity
    of obstruction-free counter implementations exists, our upper bound is within
    a logarithmic factor of the optimal. The worst-case step complexity of the construction
    remains linear, which is optimal. This is obtained thanks to a new max register
    construction with O(logn) amortized step complexity in executions of arbitrary
    length in which the value stored in the register does not grow too quickly. We
    then leverage an existing counter algorithm by Aspnes, Attiya and Censor-Hillel
    [1] in which we “plug” our max register implementation to show that it remains
    linearizable while achieving O(log2n) amortized step complexity.'
acknowledgement: A preliminary version of this work appeared in DISC’19. Mirza Ahad
  Baig, Alessia Milani and Corentin Travers are supported by ANR projects Descartes
  and FREDDA. Mirza Ahad Baig is supported by UMI Relax. Danny Hendler is supported
  by the Israel Science Foundation (Grants 380/18 and 1425/22).
article_processing_charge: No
article_type: original
author:
- first_name: Mirza Ahad
  full_name: Baig, Mirza Ahad
  id: 3EDE6DE4-AA5A-11E9-986D-341CE6697425
  last_name: Baig
- first_name: Danny
  full_name: Hendler, Danny
  last_name: Hendler
- first_name: Alessia
  full_name: Milani, Alessia
  last_name: Milani
- first_name: Corentin
  full_name: Travers, Corentin
  last_name: Travers
citation:
  ama: Baig MA, Hendler D, Milani A, Travers C. Long-lived counters with polylogarithmic
    amortized step complexity. <i>Distributed Computing</i>. 2023;36:29-43. doi:<a
    href="https://doi.org/10.1007/s00446-022-00439-5">10.1007/s00446-022-00439-5</a>
  apa: Baig, M. A., Hendler, D., Milani, A., &#38; Travers, C. (2023). Long-lived
    counters with polylogarithmic amortized step complexity. <i>Distributed Computing</i>.
    Springer Nature. <a href="https://doi.org/10.1007/s00446-022-00439-5">https://doi.org/10.1007/s00446-022-00439-5</a>
  chicago: Baig, Mirza Ahad, Danny Hendler, Alessia Milani, and Corentin Travers.
    “Long-Lived Counters with Polylogarithmic Amortized Step Complexity.” <i>Distributed
    Computing</i>. Springer Nature, 2023. <a href="https://doi.org/10.1007/s00446-022-00439-5">https://doi.org/10.1007/s00446-022-00439-5</a>.
  ieee: M. A. Baig, D. Hendler, A. Milani, and C. Travers, “Long-lived counters with
    polylogarithmic amortized step complexity,” <i>Distributed Computing</i>, vol.
    36. Springer Nature, pp. 29–43, 2023.
  ista: Baig MA, Hendler D, Milani A, Travers C. 2023. Long-lived counters with polylogarithmic
    amortized step complexity. Distributed Computing. 36, 29–43.
  mla: Baig, Mirza Ahad, et al. “Long-Lived Counters with Polylogarithmic Amortized
    Step Complexity.” <i>Distributed Computing</i>, vol. 36, Springer Nature, 2023,
    pp. 29–43, doi:<a href="https://doi.org/10.1007/s00446-022-00439-5">10.1007/s00446-022-00439-5</a>.
  short: M.A. Baig, D. Hendler, A. Milani, C. Travers, Distributed Computing 36 (2023)
    29–43.
date_created: 2023-01-12T12:10:08Z
date_published: 2023-03-01T00:00:00Z
date_updated: 2023-08-16T08:39:36Z
day: '01'
department:
- _id: KrPi
doi: 10.1007/s00446-022-00439-5
external_id:
  isi:
  - '000890138700001'
intvolume: '        36'
isi: 1
keyword:
- Computational Theory and Mathematics
- Computer Networks and Communications
- Hardware and Architecture
- Theoretical Computer Science
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://drops.dagstuhl.de/opus/volltexte/2019/11310/
month: '03'
oa: 1
oa_version: Preprint
page: 29-43
publication: Distributed Computing
publication_identifier:
  eissn:
  - 1432-0452
  issn:
  - 0178-2770
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Long-lived counters with polylogarithmic amortized step complexity
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 36
year: '2023'
...
