---
_id: '1782'
abstract:
- lang: eng
text: Steering a quantum harmonic oscillator state along cyclic trajectories leads
to a path-dependent geometric phase. Here we describe its experimental observation
in an electronic harmonic oscillator. We use a superconducting qubit as a nonlinear
probe of the phase, which is otherwise unobservable due to the linearity of the
oscillator. We show that the geometric phase is, for a variety of cyclic paths,
proportional to the area enclosed in the quadrature plane. At the transition to
the nonadiabatic regime, we study corrections to the phase and dephasing of the
qubit caused by qubit-resonator entanglement. In particular, we identify parameters
for which this dephasing mechanism is negligible even in the nonadiabatic regime.
The demonstrated controllability makes our system a versatile tool to study geometric
phases in open quantum systems and to investigate their potential for quantum
information processing.
acknowledgement: This work is supported by the EU project GEOMDISS, the Austrian Science
Foundation (S. F.), and the Swiss National Science Foundation (SNSF)
author:
- first_name: M
full_name: Pechal, M
last_name: Pechal
- first_name: Stefan
full_name: Berger, Stefan T
last_name: Berger
- first_name: Abdufarrukh
full_name: Abdumalikov, Abdufarrukh A
last_name: Abdumalikov
- first_name: Johannes M
full_name: Johannes Fink
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
- first_name: Jonas
full_name: Mlynek, Jonas A
last_name: Mlynek
- first_name: L.
full_name: Steffen, L. Kraig
last_name: Steffen
- first_name: Andreas
full_name: Wallraff, Andreas
last_name: Wallraff
- first_name: Stefan
full_name: Filipp, Stefan
last_name: Filipp
citation:
ama: Pechal M, Berger S, Abdumalikov A, et al. Geometric phase and nonadiabatic
effects in an electronic harmonic oscillator. Physical Review Letters.
2012;108(17). doi:10.1103/PhysRevLett.108.170401
apa: Pechal, M., Berger, S., Abdumalikov, A., Fink, J. M., Mlynek, J., Steffen,
L., … Filipp, S. (2012). Geometric phase and nonadiabatic effects in an electronic
harmonic oscillator. Physical Review Letters. American Physical Society.
https://doi.org/10.1103/PhysRevLett.108.170401
chicago: Pechal, M, Stefan Berger, Abdufarrukh Abdumalikov, Johannes M Fink, Jonas
Mlynek, L. Steffen, Andreas Wallraff, and Stefan Filipp. “Geometric Phase and
Nonadiabatic Effects in an Electronic Harmonic Oscillator.” Physical Review
Letters. American Physical Society, 2012. https://doi.org/10.1103/PhysRevLett.108.170401.
ieee: M. Pechal et al., “Geometric phase and nonadiabatic effects in an electronic
harmonic oscillator,” Physical Review Letters, vol. 108, no. 17. American
Physical Society, 2012.
ista: Pechal M, Berger S, Abdumalikov A, Fink JM, Mlynek J, Steffen L, Wallraff
A, Filipp S. 2012. Geometric phase and nonadiabatic effects in an electronic harmonic
oscillator. Physical Review Letters. 108(17).
mla: Pechal, M., et al. “Geometric Phase and Nonadiabatic Effects in an Electronic
Harmonic Oscillator.” Physical Review Letters, vol. 108, no. 17, American
Physical Society, 2012, doi:10.1103/PhysRevLett.108.170401.
short: M. Pechal, S. Berger, A. Abdumalikov, J.M. Fink, J. Mlynek, L. Steffen, A.
Wallraff, S. Filipp, Physical Review Letters 108 (2012).
date_created: 2018-12-11T11:53:59Z
date_published: 2012-04-23T00:00:00Z
date_updated: 2021-01-12T06:53:10Z
day: '23'
doi: 10.1103/PhysRevLett.108.170401
extern: 1
intvolume: ' 108'
issue: '17'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1109.1157
month: '04'
oa: 1
publication: Physical Review Letters
publication_status: published
publisher: American Physical Society
publist_id: '5333'
quality_controlled: 0
status: public
title: Geometric phase and nonadiabatic effects in an electronic harmonic oscillator
type: journal_article
volume: 108
year: '2012'
...
---
_id: '1783'
abstract:
- lang: eng
text: Nonlinearity and entanglement are two important properties by which physical
systems can be identified as nonclassical. We study the dynamics of the resonant
interaction of up to N=3 two-level systems and a single mode of the electromagnetic
field sharing a single excitation dynamically. We observe coherent vacuum Rabi
oscillations and their nonlinear √N speedup by tracking the populations of all
qubits and the resonator in time. We use quantum state tomography to show explicitly
that the dynamics generates maximally entangled states of the W class in a time
limited only by the collective interaction rate. We use an entanglement witness
and the 3-tangle to characterize the state whose fidelity F=78% is limited in
our experiments by crosstalk arising during the simultaneous qubit manipulations
which is absent in a sequential approach with F=91%.
acknowledgement: This work was supported by the Swiss National Science Foundation
(SNF) and the EU IP SOLID
author:
- first_name: Jonas
full_name: Mlynek, Jonas A
last_name: Mlynek
- first_name: Abdufarrukh
full_name: Abdumalikov, Abdufarrukh A
last_name: Abdumalikov
- first_name: Johannes M
full_name: Johannes Fink
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
- first_name: L.
full_name: Steffen, L. Kraig
last_name: Steffen
- first_name: Matthias
full_name: Baur, Matthias P
last_name: Baur
- first_name: C
full_name: Lang, C
last_name: Lang
- first_name: Arjan
full_name: Van Loo, Arjan F
last_name: Van Loo
- first_name: Andreas
full_name: Wallraff, Andreas
last_name: Wallraff
citation:
ama: Mlynek J, Abdumalikov A, Fink JM, et al. Demonstrating W-type entanglement
of Dicke states in resonant cavity quantum electrodynamics. Physical Review
A - Atomic, Molecular, and Optical Physics. 2012;86(5). doi:10.1103/PhysRevA.86.053838
apa: Mlynek, J., Abdumalikov, A., Fink, J. M., Steffen, L., Baur, M., Lang, C.,
… Wallraff, A. (2012). Demonstrating W-type entanglement of Dicke states in resonant
cavity quantum electrodynamics. Physical Review A - Atomic, Molecular, and
Optical Physics. American Physical Society. https://doi.org/10.1103/PhysRevA.86.053838
chicago: Mlynek, Jonas, Abdufarrukh Abdumalikov, Johannes M Fink, L. Steffen, Matthias
Baur, C Lang, Arjan Van Loo, and Andreas Wallraff. “Demonstrating W-Type Entanglement
of Dicke States in Resonant Cavity Quantum Electrodynamics.” Physical Review
A - Atomic, Molecular, and Optical Physics. American Physical Society, 2012.
https://doi.org/10.1103/PhysRevA.86.053838.
ieee: J. Mlynek et al., “Demonstrating W-type entanglement of Dicke states
in resonant cavity quantum electrodynamics,” Physical Review A - Atomic, Molecular,
and Optical Physics, vol. 86, no. 5. American Physical Society, 2012.
ista: Mlynek J, Abdumalikov A, Fink JM, Steffen L, Baur M, Lang C, Van Loo A, Wallraff
A. 2012. Demonstrating W-type entanglement of Dicke states in resonant cavity
quantum electrodynamics. Physical Review A - Atomic, Molecular, and Optical Physics.
86(5).
mla: Mlynek, Jonas, et al. “Demonstrating W-Type Entanglement of Dicke States in
Resonant Cavity Quantum Electrodynamics.” Physical Review A - Atomic, Molecular,
and Optical Physics, vol. 86, no. 5, American Physical Society, 2012, doi:10.1103/PhysRevA.86.053838.
short: J. Mlynek, A. Abdumalikov, J.M. Fink, L. Steffen, M. Baur, C. Lang, A. Van
Loo, A. Wallraff, Physical Review A - Atomic, Molecular, and Optical Physics 86
(2012).
date_created: 2018-12-11T11:53:59Z
date_published: 2012-11-30T00:00:00Z
date_updated: 2021-01-12T06:53:10Z
day: '30'
doi: 10.1103/PhysRevA.86.053838
extern: 1
intvolume: ' 86'
issue: '5'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1202.5191
month: '11'
oa: 1
publication: Physical Review A - Atomic, Molecular, and Optical Physics
publication_status: published
publisher: American Physical Society
publist_id: '5332'
quality_controlled: 0
status: public
title: Demonstrating W-type entanglement of Dicke states in resonant cavity quantum
electrodynamics
type: journal_article
volume: 86
year: '2012'
...
---
_id: '1784'
abstract:
- lang: eng
text: A localized qubit entangled with a propagating quantum field is well suited
to study nonlocal aspects of quantum mechanics and may also provide a channel
to communicate between spatially separated nodes in a quantum network. Here, we
report the on-demand generation and characterization of Bell-type entangled states
between a superconducting qubit and propagating microwave fields composed of zero-,
one-, and two-photon Fock states. Using low noise linear amplification and efficient
data acquisition we extract all relevant correlations between the qubit and the
photon states and demonstrate entanglement with high fidelity.
acknowledgement: This work was supported by the European Research Council (ERC) through
a Starting Grant and by ETHZ
author:
- first_name: Christopher
full_name: Eichler, Christopher
last_name: Eichler
- first_name: C
full_name: Lang, C
last_name: Lang
- first_name: Johannes M
full_name: Johannes Fink
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
- first_name: J
full_name: Govenius, J
last_name: Govenius
- first_name: Stefan
full_name: Filipp, Stefan
last_name: Filipp
- first_name: Andreas
full_name: Wallraff, Andreas
last_name: Wallraff
citation:
ama: Eichler C, Lang C, Fink JM, Govenius J, Filipp S, Wallraff A. Observation of
entanglement between itinerant microwave photons and a superconducting qubit.
Physical Review Letters. 2012;109(24). doi:10.1103/PhysRevLett.109.240501
apa: Eichler, C., Lang, C., Fink, J. M., Govenius, J., Filipp, S., & Wallraff,
A. (2012). Observation of entanglement between itinerant microwave photons and
a superconducting qubit. Physical Review Letters. American Physical Society.
https://doi.org/10.1103/PhysRevLett.109.240501
chicago: Eichler, Christopher, C Lang, Johannes M Fink, J Govenius, Stefan Filipp,
and Andreas Wallraff. “Observation of Entanglement between Itinerant Microwave
Photons and a Superconducting Qubit.” Physical Review Letters. American
Physical Society, 2012. https://doi.org/10.1103/PhysRevLett.109.240501.
ieee: C. Eichler, C. Lang, J. M. Fink, J. Govenius, S. Filipp, and A. Wallraff,
“Observation of entanglement between itinerant microwave photons and a superconducting
qubit,” Physical Review Letters, vol. 109, no. 24. American Physical Society,
2012.
ista: Eichler C, Lang C, Fink JM, Govenius J, Filipp S, Wallraff A. 2012. Observation
of entanglement between itinerant microwave photons and a superconducting qubit.
Physical Review Letters. 109(24).
mla: Eichler, Christopher, et al. “Observation of Entanglement between Itinerant
Microwave Photons and a Superconducting Qubit.” Physical Review Letters,
vol. 109, no. 24, American Physical Society, 2012, doi:10.1103/PhysRevLett.109.240501.
short: C. Eichler, C. Lang, J.M. Fink, J. Govenius, S. Filipp, A. Wallraff, Physical
Review Letters 109 (2012).
date_created: 2018-12-11T11:53:59Z
date_published: 2012-12-10T00:00:00Z
date_updated: 2021-01-12T06:53:10Z
day: '10'
doi: 10.1103/PhysRevLett.109.240501
extern: 1
intvolume: ' 109'
issue: '24'
main_file_link:
- open_access: '0'
url: http://arxiv.org/abs/1209.0441
month: '12'
publication: Physical Review Letters
publication_status: published
publisher: American Physical Society
publist_id: '5330'
quality_controlled: 0
status: public
title: Observation of entanglement between itinerant microwave photons and a superconducting
qubit
type: journal_article
volume: 109
year: '2012'
...
---
_id: '1801'
abstract:
- lang: eng
text: Brain circuits are assembled from a large variety of morphologically and functionally
diverse cell types. It is not known how the intermingled cell types of an individual
adult brain region differ in their expressed genomes. Here we describe an atlas
of cell type transcriptomes in one brain region, the mouse retina. We found that
each adult cell type expressed a specific set of genes, including a unique set
of transcription factors, forming a 'barcode' for cell identity. Cell type transcriptomes
carried enough information to categorize cells into morphological classes and
types. Several genes that were specifically expressed in particular retinal circuit
elements, such as inhibitory neuron types, are associated with eye diseases. The
resource described here allows gene expression to be compared across adult retinal
cell types, experimenting with specific transcription factors to differentiate
stem or somatic cells to retinal cell types, and predicting cellular targets of
newly discovered disease-associated genes.
acknowledgement: The study was supported by Friedrich Miescher Institute funds, Alcon
award, a National Center of Competence in Research Genetics grant, a European Research
Council grant, a Swiss-Hungarian grant, and RETICIRC, TREATRUSH, SEEBETTER and OPTONEURO
grants from the European Union to B.R.
author:
- first_name: Sandra
full_name: Sandra Siegert
id: 36ACD32E-F248-11E8-B48F-1D18A9856A87
last_name: Siegert
orcid: 0000-0001-8635-0877
- first_name: Erik
full_name: Cabuy, Erik
last_name: Cabuy
- first_name: Brigitte
full_name: Scherf, Brigitte G
last_name: Scherf
- first_name: Hubertus
full_name: Kohler, Hubertus
last_name: Kohler
- first_name: Satchidananda
full_name: Panda, Satchidananda
last_name: Panda
- first_name: Yunzheng
full_name: Le, Yunzheng
last_name: Le
- first_name: Hans
full_name: Fehling, Hans J
last_name: Fehling
- first_name: Dimos
full_name: Gaidatzis, Dimos
last_name: Gaidatzis
- first_name: Michael
full_name: Stadler, Michael B
last_name: Stadler
- first_name: Botond
full_name: Roska, Botond M
last_name: Roska
citation:
ama: Siegert S, Cabuy E, Scherf B, et al. Transcriptional code and disease map for
adult retinal cell types. Nature Neuroscience. 2012;15(3):487-495. doi:10.1038/nn.3032
apa: Siegert, S., Cabuy, E., Scherf, B., Kohler, H., Panda, S., Le, Y., … Roska,
B. (2012). Transcriptional code and disease map for adult retinal cell types.
Nature Neuroscience. Nature Publishing Group. https://doi.org/10.1038/nn.3032
chicago: Siegert, Sandra, Erik Cabuy, Brigitte Scherf, Hubertus Kohler, Satchidananda
Panda, Yunzheng Le, Hans Fehling, Dimos Gaidatzis, Michael Stadler, and Botond
Roska. “Transcriptional Code and Disease Map for Adult Retinal Cell Types.” Nature
Neuroscience. Nature Publishing Group, 2012. https://doi.org/10.1038/nn.3032.
ieee: S. Siegert et al., “Transcriptional code and disease map for adult
retinal cell types,” Nature Neuroscience, vol. 15, no. 3. Nature Publishing
Group, pp. 487–495, 2012.
ista: Siegert S, Cabuy E, Scherf B, Kohler H, Panda S, Le Y, Fehling H, Gaidatzis
D, Stadler M, Roska B. 2012. Transcriptional code and disease map for adult retinal
cell types. Nature Neuroscience. 15(3), 487–495.
mla: Siegert, Sandra, et al. “Transcriptional Code and Disease Map for Adult Retinal
Cell Types.” Nature Neuroscience, vol. 15, no. 3, Nature Publishing Group,
2012, pp. 487–95, doi:10.1038/nn.3032.
short: S. Siegert, E. Cabuy, B. Scherf, H. Kohler, S. Panda, Y. Le, H. Fehling,
D. Gaidatzis, M. Stadler, B. Roska, Nature Neuroscience 15 (2012) 487–495.
date_created: 2018-12-11T11:54:05Z
date_published: 2012-03-01T00:00:00Z
date_updated: 2021-01-12T06:53:17Z
day: '01'
doi: 10.1038/nn.3032
extern: 1
intvolume: ' 15'
issue: '3'
month: '03'
page: 487 - 495
publication: Nature Neuroscience
publication_status: published
publisher: Nature Publishing Group
publist_id: '5309'
quality_controlled: 0
status: public
title: Transcriptional code and disease map for adult retinal cell types
type: journal_article
volume: 15
year: '2012'
...
---
_id: '1972'
abstract:
- lang: eng
text: Outer membrane protein F, a major component of the Escherichia coli outer
membrane, was crystallized for the first time in lipidic mesophase of monoolein
in novel space groups, P1 and H32. Due to ease of its purification and crystallization
OmpF can be used as a benchmark protein for establishing membrane protein crystallization
in meso, as a "membrane lyzozyme" The packing of porin trimers in the
crystals of space group H32 is similar to natural outer membranes, providing the
first high-resolution insight into the close to native packing of OmpF. Surprisingly,
interaction between trimers is mediated exclusively by lipids, without direct
protein-protein contacts. Multiple ordered lipids are observed and many of them
occupy identical positions independently of the space group, identifying preferential
interaction sites of lipid acyl chains. Presence of ordered aliphatic chains close
to a positively charged area on the porin surface suggests a position for a lipopolysaccharide
binding site on the surface of the major E. coli porins.
acknowledgement: This work was funded by the Medical Research Council.
author:
- first_name: Rouslan
full_name: Efremov, Rouslan G
last_name: Efremov
- first_name: Leonid A
full_name: Leonid Sazanov
id: 338D39FE-F248-11E8-B48F-1D18A9856A87
last_name: Sazanov
orcid: 0000-0002-0977-7989
citation:
ama: Efremov R, Sazanov LA. Structure of Escherichia coli OmpF porin from lipidic
mesophase. Journal of Structural Biology. 2012;178(3):311-318. doi:10.1016/j.jsb.2012.03.005
apa: Efremov, R., & Sazanov, L. A. (2012). Structure of Escherichia coli OmpF
porin from lipidic mesophase. Journal of Structural Biology. Academic Press.
https://doi.org/10.1016/j.jsb.2012.03.005
chicago: Efremov, Rouslan, and Leonid A Sazanov. “Structure of Escherichia Coli
OmpF Porin from Lipidic Mesophase.” Journal of Structural Biology. Academic
Press, 2012. https://doi.org/10.1016/j.jsb.2012.03.005.
ieee: R. Efremov and L. A. Sazanov, “Structure of Escherichia coli OmpF porin from
lipidic mesophase,” Journal of Structural Biology, vol. 178, no. 3. Academic
Press, pp. 311–318, 2012.
ista: Efremov R, Sazanov LA. 2012. Structure of Escherichia coli OmpF porin from
lipidic mesophase. Journal of Structural Biology. 178(3), 311–318.
mla: Efremov, Rouslan, and Leonid A. Sazanov. “Structure of Escherichia Coli OmpF
Porin from Lipidic Mesophase.” Journal of Structural Biology, vol. 178,
no. 3, Academic Press, 2012, pp. 311–18, doi:10.1016/j.jsb.2012.03.005.
short: R. Efremov, L.A. Sazanov, Journal of Structural Biology 178 (2012) 311–318.
date_created: 2018-12-11T11:54:59Z
date_published: 2012-06-01T00:00:00Z
date_updated: 2021-01-12T06:54:26Z
day: '01'
doi: 10.1016/j.jsb.2012.03.005
extern: 1
intvolume: ' 178'
issue: '3'
month: '06'
page: 311 - 318
publication: Journal of Structural Biology
publication_status: published
publisher: Academic Press
publist_id: '5109'
quality_controlled: 0
status: public
title: Structure of Escherichia coli OmpF porin from lipidic mesophase
type: journal_article
volume: 178
year: '2012'
...
---
_id: '1976'
abstract:
- lang: eng
text: 'Complex I is a key enzyme of the respiratory chain in many organisms. This
multi-protein complex with an intricate evolutionary history originated from the
unification of prebuilt modules of hydrogenases and transporters. Using recently
determined crystallographic structures of complex I we reanalyzed evolutionarily
related complexes that couple oxidoreduction to trans-membrane ion translocation.
Our analysis points to the previously unnoticed structural homology of the electron
input module of formate dehydrogenlyases and subunit NuoG of complex I. We also
show that all related to complex I hydrogenases likely operate via a conformation
driven mechanism with structural changes generated in the conserved coupling site
located at the interface of subunits NuoB/D/H. The coupling apparently originated
once in evolutionary history, together with subunit NuoH joining hydrogenase and
transport modules. Analysis of quinone oxidoreduction properties and the structure
of complex I allows us to suggest a fully reversible coupling mechanism. Our model
predicts that: 1) proton access to the ketone groups of the bound quinone is rigorously
controlled by the protein, 2) the negative electric charge of the anionic ubiquinol
head group is a major driving force for conformational changes.'
acknowledgement: The work in authors' laboratory was funded by the Medical Research
Council.
author:
- first_name: Rouslan
full_name: Efremov, Rouslan G
last_name: Efremov
- first_name: Leonid A
full_name: Leonid Sazanov
id: 338D39FE-F248-11E8-B48F-1D18A9856A87
last_name: Sazanov
orcid: 0000-0002-0977-7989
citation:
ama: Efremov R, Sazanov LA. The coupling mechanism of respiratory complex i - A
structural and evolutionary perspective. Biochimica et Biophysica Acta - Bioenergetics.
2012;1817(10):1785-1795. doi:10.1016/j.bbabio.2012.02.015
apa: Efremov, R., & Sazanov, L. A. (2012). The coupling mechanism of respiratory
complex i - A structural and evolutionary perspective. Biochimica et Biophysica
Acta - Bioenergetics. Elsevier. https://doi.org/10.1016/j.bbabio.2012.02.015
chicago: Efremov, Rouslan, and Leonid A Sazanov. “The Coupling Mechanism of Respiratory
Complex i - A Structural and Evolutionary Perspective.” Biochimica et Biophysica
Acta - Bioenergetics. Elsevier, 2012. https://doi.org/10.1016/j.bbabio.2012.02.015.
ieee: R. Efremov and L. A. Sazanov, “The coupling mechanism of respiratory complex
i - A structural and evolutionary perspective,” Biochimica et Biophysica Acta
- Bioenergetics, vol. 1817, no. 10. Elsevier, pp. 1785–1795, 2012.
ista: Efremov R, Sazanov LA. 2012. The coupling mechanism of respiratory complex
i - A structural and evolutionary perspective. Biochimica et Biophysica Acta -
Bioenergetics. 1817(10), 1785–1795.
mla: Efremov, Rouslan, and Leonid A. Sazanov. “The Coupling Mechanism of Respiratory
Complex i - A Structural and Evolutionary Perspective.” Biochimica et Biophysica
Acta - Bioenergetics, vol. 1817, no. 10, Elsevier, 2012, pp. 1785–95, doi:10.1016/j.bbabio.2012.02.015.
short: R. Efremov, L.A. Sazanov, Biochimica et Biophysica Acta - Bioenergetics 1817
(2012) 1785–1795.
date_created: 2018-12-11T11:55:00Z
date_published: 2012-10-01T00:00:00Z
date_updated: 2019-04-26T07:22:06Z
day: '01'
doi: 10.1016/j.bbabio.2012.02.015
extern: 1
intvolume: ' 1817'
issue: '10'
month: '10'
page: 1785 - 1795
publication: Biochimica et Biophysica Acta - Bioenergetics
publication_status: published
publisher: Elsevier
publist_id: '5108'
quality_controlled: 0
status: public
title: The coupling mechanism of respiratory complex i - A structural and evolutionary
perspective
type: review
volume: 1817
year: '2012'
...
---
_id: '1987'
abstract:
- lang: eng
text: |
In the living cell, proteins are able to organize space much larger than their dimensions. In return, changes of intracellular space can influence biochemical reactions, allowing cells to sense their size and shape. Despite the possibility to reconstitute protein self-organization with only a few purified components, we still lack knowledge of how geometrical boundaries affect spatiotemporal protein patterns. Following a minimal systems approach, we used purified proteins and photolithographically patterned membranes to study the influence of spatial confinement on the self-organization of the Min system, a spatial regulator of bacterial cytokinesis, in vitro. We found that the emerging protein pattern responds even to the lateral, two-dimensional geometry of the membrane such that, as in the three-dimensional cell, Min protein waves travel along the longest axis of the membrane patch. This shows that for spatial sensing the Min system does not need to be enclosed in a three-dimensional compartment. Using a computational model we quantitatively analyzed our experimental findings and identified persistent binding of MinE to the membrane as requirement for the Min system to sense geometry. Our results give insight into the interplay between geometrical confinement and biochemical patterns emerging from a nonlinear reaction-diffusion system.
acknowledgement: 'This work was supported by the Max-Planck-Society (P.S. and M.L.)
and by the German Research Foundation as part of the Research Training Group “Nano-
and Biotechnologies for Electronic Device Packaging” (GRK 1401) (J.S.) and by the
Leibniz-Award (P.S.). '
author:
- first_name: Jakob
full_name: Schweizer, Jakob
last_name: Schweizer
- first_name: Martin
full_name: Martin Loose
id: 462D4284-F248-11E8-B48F-1D18A9856A87
last_name: Loose
orcid: 0000-0001-7309-9724
- first_name: Mike
full_name: 'Bonny, Mike '
last_name: Bonny
- first_name: Karsten
full_name: Kruse, Karsten
last_name: Kruse
- first_name: Ingolf
full_name: Mönch, Ingolf
last_name: Mönch
- first_name: Petra
full_name: 'Schwille, Petra '
last_name: Schwille
citation:
ama: Schweizer J, Loose M, Bonny M, Kruse K, Mönch I, Schwille P. Geometry sensing
by self-organized protein patterns. PNAS. 2012;109(38):15283-15288. doi:10.1073/pnas.1206953109
apa: Schweizer, J., Loose, M., Bonny, M., Kruse, K., Mönch, I., & Schwille,
P. (2012). Geometry sensing by self-organized protein patterns. PNAS. National
Academy of Sciences. https://doi.org/10.1073/pnas.1206953109
chicago: Schweizer, Jakob, Martin Loose, Mike Bonny, Karsten Kruse, Ingolf Mönch,
and Petra Schwille. “Geometry Sensing by Self-Organized Protein Patterns.” PNAS.
National Academy of Sciences, 2012. https://doi.org/10.1073/pnas.1206953109.
ieee: J. Schweizer, M. Loose, M. Bonny, K. Kruse, I. Mönch, and P. Schwille, “Geometry
sensing by self-organized protein patterns,” PNAS, vol. 109, no. 38. National
Academy of Sciences, pp. 15283–15288, 2012.
ista: Schweizer J, Loose M, Bonny M, Kruse K, Mönch I, Schwille P. 2012. Geometry
sensing by self-organized protein patterns. PNAS. 109(38), 15283–15288.
mla: Schweizer, Jakob, et al. “Geometry Sensing by Self-Organized Protein Patterns.”
PNAS, vol. 109, no. 38, National Academy of Sciences, 2012, pp. 15283–88,
doi:10.1073/pnas.1206953109.
short: J. Schweizer, M. Loose, M. Bonny, K. Kruse, I. Mönch, P. Schwille, PNAS 109
(2012) 15283–15288.
date_created: 2018-12-11T11:55:04Z
date_published: 2012-09-18T00:00:00Z
date_updated: 2021-01-12T06:54:31Z
day: '18'
doi: 10.1073/pnas.1206953109
extern: 1
intvolume: ' 109'
issue: '38'
month: '09'
page: 15283 - 15288
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '5096'
quality_controlled: 0
status: public
title: Geometry sensing by self-organized protein patterns
type: journal_article
volume: 109
year: '2012'
...
---
_id: '2048'
abstract:
- lang: eng
text: Leakage resilient cryptography attempts to incorporate side-channel leakage
into the black-box security model and designs cryptographic schemes that are provably
secure within it. Informally, a scheme is leakage-resilient if it remains secure
even if an adversary learns a bounded amount of arbitrary information about the
schemes internal state. Unfortunately, most leakage resilient schemes are unnecessarily
complicated in order to achieve strong provable security guarantees. As advocated
by Yu et al. [CCS’10], this mostly is an artefact of the security proof and in
practice much simpler construction may already suffice to protect against realistic
side-channel attacks. In this paper, we show that indeed for simpler constructions
leakage-resilience can be obtained when we aim for relaxed security notions where
the leakage-functions and/or the inputs to the primitive are chosen non-adaptively.
For example, we show that a three round Feistel network instantiated with a leakage
resilient PRF yields a leakage resilient PRP if the inputs are chosen non-adaptively
(This complements the result of Dodis and Pietrzak [CRYPTO’10] who show that if
a adaptive queries are allowed, a superlogarithmic number of rounds is necessary.)
We also show that a minor variation of the classical GGM construction gives a
leakage resilient PRF if both, the leakage-function and the inputs, are chosen
non-adaptively.
acknowledgement: "Sebastian Faust acknowledges support from the Danish National Research
Foundation and The National Science Foundation of China (under the grant 61061130540)
for the Sino-Danish Center for the Theory of Interactive Computation, within part
of this work was performed; and from the CFEM research center, supported by the
Danish Strategic Research Council. \r\nSupported by the European Research Council/ERC
Starting Grant 259668-PSPC.\r\n"
alternative_title:
- LNCS
author:
- first_name: Sebastian
full_name: Faust, Sebastian
last_name: Faust
- first_name: Krzysztof Z
full_name: Pietrzak, Krzysztof Z
id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
last_name: Pietrzak
orcid: 0000-0002-9139-1654
- first_name: Joachim
full_name: Schipper, Joachim
id: 7BE863D4-E9CF-11E9-9EDB-90527418172C
last_name: Schipper
citation:
ama: 'Faust S, Pietrzak KZ, Schipper J. Practical leakage-resilient symmetric cryptography.
In: Conference Proceedings CHES 2012. Vol 7428. Springer; 2012:213-232.
doi:10.1007/978-3-642-33027-8_13'
apa: 'Faust, S., Pietrzak, K. Z., & Schipper, J. (2012). Practical leakage-resilient
symmetric cryptography. In Conference proceedings CHES 2012 (Vol. 7428,
pp. 213–232). Leuven, Belgium: Springer. https://doi.org/10.1007/978-3-642-33027-8_13'
chicago: Faust, Sebastian, Krzysztof Z Pietrzak, and Joachim Schipper. “Practical
Leakage-Resilient Symmetric Cryptography.” In Conference Proceedings CHES
2012, 7428:213–32. Springer, 2012. https://doi.org/10.1007/978-3-642-33027-8_13.
ieee: S. Faust, K. Z. Pietrzak, and J. Schipper, “Practical leakage-resilient symmetric
cryptography,” in Conference proceedings CHES 2012, Leuven, Belgium, 2012,
vol. 7428, pp. 213–232.
ista: 'Faust S, Pietrzak KZ, Schipper J. 2012. Practical leakage-resilient symmetric
cryptography. Conference proceedings CHES 2012. CHES: Cryptographic Hardware
and Embedded Systems, LNCS, vol. 7428, 213–232.'
mla: Faust, Sebastian, et al. “Practical Leakage-Resilient Symmetric Cryptography.”
Conference Proceedings CHES 2012, vol. 7428, Springer, 2012, pp. 213–32,
doi:10.1007/978-3-642-33027-8_13.
short: S. Faust, K.Z. Pietrzak, J. Schipper, in:, Conference Proceedings CHES 2012,
Springer, 2012, pp. 213–232.
conference:
end_date: 2012-09-12
location: Leuven, Belgium
name: 'CHES: Cryptographic Hardware and Embedded Systems'
start_date: 2012-09-09
date_created: 2018-12-11T11:55:25Z
date_published: 2012-09-01T00:00:00Z
date_updated: 2021-01-12T06:54:58Z
day: '01'
department:
- _id: KrPi
doi: 10.1007/978-3-642-33027-8_13
ec_funded: 1
intvolume: ' 7428'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.iacr.org/archive/ches2012/74280211/74280211.pdf
month: '09'
oa: 1
oa_version: Preprint
page: 213 - 232
project:
- _id: 258C570E-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '259668'
name: Provable Security for Physical Cryptography
publication: ' Conference proceedings CHES 2012'
publication_status: published
publisher: Springer
publist_id: '5003'
quality_controlled: '1'
scopus_import: 1
status: public
title: Practical leakage-resilient symmetric cryptography
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 7428
year: '2012'
...
---
_id: '2049'
abstract:
- lang: eng
text: "We propose a new authentication protocol that is provably secure based on
a ring variant of the learning parity with noise (LPN) problem. The protocol follows
the design principle of the LPN-based protocol from Eurocrypt’11 (Kiltz et al.),
and like it, is a two round protocol secure against active attacks. Moreover,
our protocol has small communication complexity and a very small footprint which
makes it applicable in scenarios that involve low-cost, resource-constrained devices.\r\n\r\nPerformance-wise,
our protocol is more efficient than previous LPN-based schemes, such as the many
variants of the Hopper-Blum (HB) protocol and the aforementioned protocol from
Eurocrypt’11. Our implementation results show that it is even comparable to the
standard challenge-and-response protocols based on the AES block-cipher. Our basic
protocol is roughly 20 times slower than AES, but with the advantage of having
10 times smaller code size. Furthermore, if a few hundred bytes of non-volatile
memory are available to allow the storage of some off-line pre-computations, then
the online phase of our protocols is only twice as slow as AES.\r\n"
acknowledgement: "Supported by the European Research Council / ERC Starting Grant
(259668- PSPC)\r\nWe would like to thank the anonymous referees of this confer-
ence and those of the ECRYPT Workshop on Lightweight Cryptography for very useful
comments, and in particular for the suggestion that the scheme is somewhat vulnerable
to a man-in-the-middle attack whenever an adversary observes two reader challenges
that are the same. We hope that the attack we described in Appendix A corresponds
to what the reviewer had in mind. We also thank Tanja Lange for pointing us to the
pa- per of [Kir11] and for discussions of some of her recent work. "
alternative_title:
- LNCS
author:
- first_name: Stefan
full_name: Heyse, Stefan
last_name: Heyse
- first_name: Eike
full_name: Kiltz, Eike
last_name: Kiltz
- first_name: Vadim
full_name: Lyubashevsky, Vadim
last_name: Lyubashevsky
- first_name: Christof
full_name: Paar, Christof
last_name: Paar
- first_name: Krzysztof Z
full_name: Pietrzak, Krzysztof Z
id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
last_name: Pietrzak
orcid: 0000-0002-9139-1654
citation:
ama: 'Heyse S, Kiltz E, Lyubashevsky V, Paar C, Pietrzak KZ. Lapin: An efficient
authentication protocol based on ring-LPN. In: Conference Proceedings FSE
2012. Vol 7549. Springer; 2012:346-365. doi:10.1007/978-3-642-34047-5_20'
apa: 'Heyse, S., Kiltz, E., Lyubashevsky, V., Paar, C., & Pietrzak, K. Z. (2012).
Lapin: An efficient authentication protocol based on ring-LPN. In Conference
proceedings FSE 2012 (Vol. 7549, pp. 346–365). Washington, DC, USA: Springer.
https://doi.org/10.1007/978-3-642-34047-5_20'
chicago: 'Heyse, Stefan, Eike Kiltz, Vadim Lyubashevsky, Christof Paar, and Krzysztof
Z Pietrzak. “Lapin: An Efficient Authentication Protocol Based on Ring-LPN.” In
Conference Proceedings FSE 2012, 7549:346–65. Springer, 2012. https://doi.org/10.1007/978-3-642-34047-5_20.'
ieee: 'S. Heyse, E. Kiltz, V. Lyubashevsky, C. Paar, and K. Z. Pietrzak, “Lapin:
An efficient authentication protocol based on ring-LPN,” in Conference proceedings
FSE 2012, Washington, DC, USA, 2012, vol. 7549, pp. 346–365.'
ista: 'Heyse S, Kiltz E, Lyubashevsky V, Paar C, Pietrzak KZ. 2012. Lapin: An efficient
authentication protocol based on ring-LPN. Conference proceedings FSE 2012. FSE:
Fast Software Encryption, LNCS, vol. 7549, 346–365.'
mla: 'Heyse, Stefan, et al. “Lapin: An Efficient Authentication Protocol Based on
Ring-LPN.” Conference Proceedings FSE 2012, vol. 7549, Springer, 2012,
pp. 346–65, doi:10.1007/978-3-642-34047-5_20.'
short: S. Heyse, E. Kiltz, V. Lyubashevsky, C. Paar, K.Z. Pietrzak, in:, Conference
Proceedings FSE 2012, Springer, 2012, pp. 346–365.
conference:
end_date: 2012-03-21
location: Washington, DC, USA
name: 'FSE: Fast Software Encryption'
start_date: 2012-03-19
date_created: 2018-12-11T11:55:25Z
date_published: 2012-03-01T00:00:00Z
date_updated: 2021-01-12T06:54:58Z
day: '01'
department:
- _id: KrPi
doi: 10.1007/978-3-642-34047-5_20
ec_funded: 1
intvolume: ' 7549'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.iacr.org/archive/fse2012/75490350/75490350.pdf
month: '03'
oa: 1
oa_version: Preprint
page: 346 - 365
project:
- _id: 258C570E-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '259668'
name: Provable Security for Physical Cryptography
publication: ' Conference proceedings FSE 2012'
publication_status: published
publisher: Springer
publist_id: '5002'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'Lapin: An efficient authentication protocol based on ring-LPN'
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 7549
year: '2012'
...
---
_id: '13407'
abstract:
- lang: eng
text: We show that diamagnetic particles can be remotely manipulated by a magnet
by the reversible adsorption of dual-responsive, light-switchable/superparamagnetic
nanoparticles down to their surface. Adsorption occurs upon exposure to UV light,
and can be reversed thermally or by ambient light. The dynamic self-assembly of
thin films of the dual-responsive nanoparticles induces attractive interactions
between diamagnetic particles. We demonstrate that catalytic amounts of the dual-responsive
nanoparticles are sufficient to magnetically guide and deliver the diamagnetic
particles to desired locations, where they can then be released by disassembling
the dynamic layers of superparamagnetic nanoparticles with visible light.
article_processing_charge: No
article_type: original
author:
- first_name: Olga
full_name: Chovnik, Olga
last_name: Chovnik
- first_name: Renata
full_name: Balgley, Renata
last_name: Balgley
- first_name: Joel R.
full_name: Goldman, Joel R.
last_name: Goldman
- first_name: Rafal
full_name: Klajn, Rafal
id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
last_name: Klajn
citation:
ama: Chovnik O, Balgley R, Goldman JR, Klajn R. Dynamically self-assembling carriers
enable guiding of diamagnetic particles by weak magnets. Journal of the American
Chemical Society. 2012;134(48):19564-19567. doi:10.1021/ja309633v
apa: Chovnik, O., Balgley, R., Goldman, J. R., & Klajn, R. (2012). Dynamically
self-assembling carriers enable guiding of diamagnetic particles by weak magnets.
Journal of the American Chemical Society. American Chemical Society. https://doi.org/10.1021/ja309633v
chicago: Chovnik, Olga, Renata Balgley, Joel R. Goldman, and Rafal Klajn. “Dynamically
Self-Assembling Carriers Enable Guiding of Diamagnetic Particles by Weak Magnets.”
Journal of the American Chemical Society. American Chemical Society, 2012.
https://doi.org/10.1021/ja309633v.
ieee: O. Chovnik, R. Balgley, J. R. Goldman, and R. Klajn, “Dynamically self-assembling
carriers enable guiding of diamagnetic particles by weak magnets,” Journal
of the American Chemical Society, vol. 134, no. 48. American Chemical Society,
pp. 19564–19567, 2012.
ista: Chovnik O, Balgley R, Goldman JR, Klajn R. 2012. Dynamically self-assembling
carriers enable guiding of diamagnetic particles by weak magnets. Journal of the
American Chemical Society. 134(48), 19564–19567.
mla: Chovnik, Olga, et al. “Dynamically Self-Assembling Carriers Enable Guiding
of Diamagnetic Particles by Weak Magnets.” Journal of the American Chemical
Society, vol. 134, no. 48, American Chemical Society, 2012, pp. 19564–67,
doi:10.1021/ja309633v.
short: O. Chovnik, R. Balgley, J.R. Goldman, R. Klajn, Journal of the American Chemical
Society 134 (2012) 19564–19567.
date_created: 2023-08-01T09:47:42Z
date_published: 2012-11-26T00:00:00Z
date_updated: 2023-08-08T07:51:10Z
day: '26'
doi: 10.1021/ja309633v
extern: '1'
external_id:
pmid:
- '23181449'
intvolume: ' 134'
issue: '48'
keyword:
- Colloid and Surface Chemistry
- Biochemistry
- General Chemistry
- Catalysis
language:
- iso: eng
month: '11'
oa_version: Published Version
page: 19564-19567
pmid: 1
publication: Journal of the American Chemical Society
publication_identifier:
eissn:
- 1520-5126
issn:
- 0002-7863
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Dynamically self-assembling carriers enable guiding of diamagnetic particles
by weak magnets
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 134
year: '2012'
...
---
_id: '13408'
abstract:
- lang: eng
text: Well-defined metallic nanobowls can be prepared by extending the concept of
a protecting group to colloidal synthesis. Magnetic nanoparticles are employed
as “protecting groups” during the galvanic replacement of silver with gold. The
replacement reaction is accompanied by spontantous dissociation of the protecting
groups, leaving behind metallic nanobowls.
article_processing_charge: No
article_type: original
author:
- first_name: Yonatan
full_name: Ridelman, Yonatan
last_name: Ridelman
- first_name: Gurvinder
full_name: Singh, Gurvinder
last_name: Singh
- first_name: Ronit
full_name: Popovitz-Biro, Ronit
last_name: Popovitz-Biro
- first_name: Sharon G.
full_name: Wolf, Sharon G.
last_name: Wolf
- first_name: Sanjib
full_name: Das, Sanjib
last_name: Das
- first_name: Rafal
full_name: Klajn, Rafal
id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
last_name: Klajn
citation:
ama: Ridelman Y, Singh G, Popovitz-Biro R, Wolf SG, Das S, Klajn R. Metallic nanobowls
by galvanic replacement reaction on heterodimeric nanoparticles. Small.
2012;8(5):654-660. doi:10.1002/smll.201101882
apa: Ridelman, Y., Singh, G., Popovitz-Biro, R., Wolf, S. G., Das, S., & Klajn,
R. (2012). Metallic nanobowls by galvanic replacement reaction on heterodimeric
nanoparticles. Small. Wiley. https://doi.org/10.1002/smll.201101882
chicago: Ridelman, Yonatan, Gurvinder Singh, Ronit Popovitz-Biro, Sharon G. Wolf,
Sanjib Das, and Rafal Klajn. “Metallic Nanobowls by Galvanic Replacement Reaction
on Heterodimeric Nanoparticles.” Small. Wiley, 2012. https://doi.org/10.1002/smll.201101882.
ieee: Y. Ridelman, G. Singh, R. Popovitz-Biro, S. G. Wolf, S. Das, and R. Klajn,
“Metallic nanobowls by galvanic replacement reaction on heterodimeric nanoparticles,”
Small, vol. 8, no. 5. Wiley, pp. 654–660, 2012.
ista: Ridelman Y, Singh G, Popovitz-Biro R, Wolf SG, Das S, Klajn R. 2012. Metallic
nanobowls by galvanic replacement reaction on heterodimeric nanoparticles. Small.
8(5), 654–660.
mla: Ridelman, Yonatan, et al. “Metallic Nanobowls by Galvanic Replacement Reaction
on Heterodimeric Nanoparticles.” Small, vol. 8, no. 5, Wiley, 2012, pp.
654–60, doi:10.1002/smll.201101882.
short: Y. Ridelman, G. Singh, R. Popovitz-Biro, S.G. Wolf, S. Das, R. Klajn, Small
8 (2012) 654–660.
date_created: 2023-08-01T09:47:55Z
date_published: 2012-03-12T00:00:00Z
date_updated: 2023-08-08T07:55:10Z
day: '12'
doi: 10.1002/smll.201101882
extern: '1'
external_id:
pmid:
- '22392681'
intvolume: ' 8'
issue: '5'
keyword:
- Biomaterials
- Biotechnology
- General Materials Science
- General Chemistry
language:
- iso: eng
month: '03'
oa_version: None
page: 654-660
pmid: 1
publication: Small
publication_identifier:
eissn:
- 1613-6829
issn:
- 1613-6810
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Metallic nanobowls by galvanic replacement reaction on heterodimeric nanoparticles
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2012'
...
---
_id: '1384'
abstract:
- lang: eng
text: 'Software model checking, as an undecidable problem, has three possible outcomes:
(1) the program satisfies the specification, (2) the program does not satisfy
the specification, and (3) the model checker fails. The third outcome usually
manifests itself in a space-out, time-out, or one component of the verification
tool giving up; in all of these failing cases, significant computation is performed
by the verification tool before the failure, but no result is reported. We propose
to reformulate the model-checking problem as follows, in order to have the verification
tool report a summary of the performed work even in case of failure: given a program
and a specification, the model checker returns a condition Ψ - usually a state
predicate - such that the program satisfies the specification under the condition
Ψ - that is, as long as the program does not leave the states in which Ψ is satisfied.
In our experiments, we investigated as one major application of conditional model
checking the sequential combination of model checkers with information passing.
We give the condition that one model checker produces, as input to a second conditional
model checker, such that the verification problem for the second is restricted
to the part of the state space that is not covered by the condition, i.e., the
second model checker works on the problems that the first model checker could
not solve. Our experiments demonstrate that repeated application of conditional
model checkers, passing information from one model checker to the next, can significantly
improve the verification results and performance, i.e., we can now verify programs
that we could not verify before.'
acknowledgement: This research was supported by the Canadian NSERC grant RGPIN 341819-07, the ERC Advanced Grant
QUAREM, and the Austrian Science Fund NFN RiSE.
article_number: '57'
author:
- first_name: Dirk
full_name: Beyer, Dirk
last_name: Beyer
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Mehmet
full_name: Keremoglu, Mehmet
last_name: Keremoglu
- first_name: Philipp
full_name: Wendler, Philipp
last_name: Wendler
citation:
ama: 'Beyer D, Henzinger TA, Keremoglu M, Wendler P. Conditional model checking:
A technique to pass information between verifiers. In: Proceedings of the ACM
SIGSOFT 20th International Symposium on the Foundations of Software Engineering.
ACM; 2012. doi:10.1145/2393596.2393664'
apa: 'Beyer, D., Henzinger, T. A., Keremoglu, M., & Wendler, P. (2012). Conditional
model checking: A technique to pass information between verifiers. In Proceedings
of the ACM SIGSOFT 20th International Symposium on the Foundations of Software
Engineering. Cary, NC, USA: ACM. https://doi.org/10.1145/2393596.2393664'
chicago: 'Beyer, Dirk, Thomas A Henzinger, Mehmet Keremoglu, and Philipp Wendler.
“Conditional Model Checking: A Technique to Pass Information between Verifiers.”
In Proceedings of the ACM SIGSOFT 20th International Symposium on the Foundations
of Software Engineering. ACM, 2012. https://doi.org/10.1145/2393596.2393664.'
ieee: 'D. Beyer, T. A. Henzinger, M. Keremoglu, and P. Wendler, “Conditional model
checking: A technique to pass information between verifiers,” in Proceedings
of the ACM SIGSOFT 20th International Symposium on the Foundations of Software
Engineering, Cary, NC, USA, 2012.'
ista: 'Beyer D, Henzinger TA, Keremoglu M, Wendler P. 2012. Conditional model checking:
A technique to pass information between verifiers. Proceedings of the ACM SIGSOFT
20th International Symposium on the Foundations of Software Engineering. FSE:
Foundations of Software Engineering, 57.'
mla: 'Beyer, Dirk, et al. “Conditional Model Checking: A Technique to Pass Information
between Verifiers.” Proceedings of the ACM SIGSOFT 20th International Symposium
on the Foundations of Software Engineering, 57, ACM, 2012, doi:10.1145/2393596.2393664.'
short: D. Beyer, T.A. Henzinger, M. Keremoglu, P. Wendler, in:, Proceedings of the
ACM SIGSOFT 20th International Symposium on the Foundations of Software Engineering,
ACM, 2012.
conference:
end_date: 2012-11-16
location: Cary, NC, USA
name: 'FSE: Foundations of Software Engineering'
start_date: 2012-11-11
date_created: 2018-12-11T11:51:42Z
date_published: 2012-11-01T00:00:00Z
date_updated: 2021-01-12T06:50:18Z
day: '01'
department:
- _id: ToHe
doi: 10.1145/2393596.2393664
ec_funded: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1109.6926
month: '11'
oa: 1
oa_version: Preprint
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
publication: Proceedings of the ACM SIGSOFT 20th International Symposium on the Foundations
of Software Engineering
publication_status: published
publisher: ACM
publist_id: '5826'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'Conditional model checking: A technique to pass information between verifiers'
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
year: '2012'
...
---
_id: '1471'
abstract:
- lang: eng
text: 'Given a possibly reducible and non-reduced spectral cover π: X → C over a
smooth projective complex curve C we determine the group of connected components
of the Prym variety Prym(X/C). As an immediate application we show that the finite
group of n-torsion points of the Jacobian of C acts trivially on the cohomology
of the twisted SL n-Higgs moduli space up to the degree which is predicted by
topological mirror symmetry. In particular this yields a new proof of a result
of Harder-Narasimhan, showing that this finite group acts trivially on the cohomology
of the twisted SL n stable bundle moduli space.'
author:
- first_name: Tamas
full_name: Tamas Hausel
id: 4A0666D8-F248-11E8-B48F-1D18A9856A87
last_name: Hausel
- first_name: Christian
full_name: Pauly, Christian
last_name: Pauly
citation:
ama: Hausel T, Pauly C. Prym varieties of spectral covers. Geometry and Topology.
2012;16(3):1609-1638. doi:10.2140/gt.2012.16.1609
apa: Hausel, T., & Pauly, C. (2012). Prym varieties of spectral covers. Geometry
and Topology. University of Warwick. https://doi.org/10.2140/gt.2012.16.1609
chicago: Hausel, Tamás, and Christian Pauly. “Prym Varieties of Spectral Covers.”
Geometry and Topology. University of Warwick, 2012. https://doi.org/10.2140/gt.2012.16.1609.
ieee: T. Hausel and C. Pauly, “Prym varieties of spectral covers,” Geometry and
Topology, vol. 16, no. 3. University of Warwick, pp. 1609–1638, 2012.
ista: Hausel T, Pauly C. 2012. Prym varieties of spectral covers. Geometry and Topology.
16(3), 1609–1638.
mla: Hausel, Tamás, and Christian Pauly. “Prym Varieties of Spectral Covers.” Geometry
and Topology, vol. 16, no. 3, University of Warwick, 2012, pp. 1609–38, doi:10.2140/gt.2012.16.1609.
short: T. Hausel, C. Pauly, Geometry and Topology 16 (2012) 1609–1638.
date_created: 2018-12-11T11:52:13Z
date_published: 2012-08-01T00:00:00Z
date_updated: 2021-01-12T06:50:58Z
day: '01'
doi: 10.2140/gt.2012.16.1609
extern: 1
intvolume: ' 16'
issue: '3'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1012.4748
month: '08'
oa: 1
page: 1609 - 1638
publication: Geometry and Topology
publication_status: published
publisher: University of Warwick
publist_id: '5726'
quality_controlled: 0
status: public
title: Prym varieties of spectral covers
type: journal_article
volume: 16
year: '2012'
...
---
_id: '1472'
abstract:
- lang: eng
text: For G = GL 2, PGL 2, SL 2 we prove that the perverse filtration associated
with the Hitchin map on the rational cohomology of the moduli space of twisted
G-Higgs bundles on a compact Riemann surface C agrees with the weight filtration
on the rational cohomology of the twisted G character variety of C when the cohomologies
are identified via non-Abelian Hodge theory. The proof is accomplished by means
of a study of the topology of the Hitchin map over the locus of integral spectral
curves.
acknowledgement: Mark Andrea A. de Cataldo was partially supported by N.S.A. and N.S.F.
Tamás Hausel was supported by a Royal Society University Research Fellowship. Luca
Migliorini was partially supported by PRIN 2007 project "Spazi di moduli e teoria
di Lie"
author:
- first_name: Mark
full_name: De Cataldo, Mark A
last_name: De Cataldo
- first_name: Tamas
full_name: Tamas Hausel
id: 4A0666D8-F248-11E8-B48F-1D18A9856A87
last_name: Hausel
- first_name: Luca
full_name: Migliorini, Luca
last_name: Migliorini
citation:
ama: 'De Cataldo M, Hausel T, Migliorini L. Topology of hitchin systems and Hodge
theory of character varieties: The case A 1. Annals of Mathematics. 2012;175(3):1329-1407.
doi:10.4007/annals.2012.175.3.7'
apa: 'De Cataldo, M., Hausel, T., & Migliorini, L. (2012). Topology of hitchin
systems and Hodge theory of character varieties: The case A 1. Annals of Mathematics.
Princeton University Press. https://doi.org/10.4007/annals.2012.175.3.7'
chicago: 'De Cataldo, Mark, Tamás Hausel, and Luca Migliorini. “Topology of Hitchin
Systems and Hodge Theory of Character Varieties: The Case A 1.” Annals of Mathematics.
Princeton University Press, 2012. https://doi.org/10.4007/annals.2012.175.3.7.'
ieee: 'M. De Cataldo, T. Hausel, and L. Migliorini, “Topology of hitchin systems
and Hodge theory of character varieties: The case A 1,” Annals of Mathematics,
vol. 175, no. 3. Princeton University Press, pp. 1329–1407, 2012.'
ista: 'De Cataldo M, Hausel T, Migliorini L. 2012. Topology of hitchin systems and
Hodge theory of character varieties: The case A 1. Annals of Mathematics. 175(3),
1329–1407.'
mla: 'De Cataldo, Mark, et al. “Topology of Hitchin Systems and Hodge Theory of
Character Varieties: The Case A 1.” Annals of Mathematics, vol. 175, no.
3, Princeton University Press, 2012, pp. 1329–407, doi:10.4007/annals.2012.175.3.7.'
short: M. De Cataldo, T. Hausel, L. Migliorini, Annals of Mathematics 175 (2012)
1329–1407.
date_created: 2018-12-11T11:52:13Z
date_published: 2012-05-01T00:00:00Z
date_updated: 2021-01-12T06:50:59Z
day: '01'
doi: 10.4007/annals.2012.175.3.7
extern: 1
intvolume: ' 175'
issue: '3'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1004.1420
month: '05'
oa: 1
page: 1329 - 1407
publication: Annals of Mathematics
publication_status: published
publisher: Princeton University Press
publist_id: '5727'
quality_controlled: 0
status: public
title: 'Topology of hitchin systems and Hodge theory of character varieties: The case
A 1'
type: journal_article
volume: 175
year: '2012'
...
---
_id: '5396'
abstract:
- lang: eng
text: We consider the problem of inference in agraphical model with binary variables.
While in theory it is arguably preferable to compute marginal probabilities, in
practice researchers often use MAP inference due to the availability of efficient
discrete optimization algorithms. We bridge the gap between the two approaches
by introducing the Discrete Marginals technique in which approximate marginals
are obtained by minimizing an objective function with unary and pair-wise terms
over a discretized domain. This allows the use of techniques originally devel-oped
for MAP-MRF inference and learning. We explore two ways to set up the objective
function - by discretizing the Bethe free energy and by learning it from training
data. Experimental results show that for certain types of graphs a learned function
can out-perform the Bethe approximation. We also establish a link between the
Bethe free energy and submodular functions.
alternative_title:
- IST Austria Technical Report
author:
- first_name: Filip
full_name: Korc, Filip
id: 476A2FD6-F248-11E8-B48F-1D18A9856A87
last_name: Korc
- first_name: Vladimir
full_name: Kolmogorov, Vladimir
id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
last_name: Kolmogorov
- first_name: Christoph
full_name: Lampert, Christoph
id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
last_name: Lampert
orcid: 0000-0001-8622-7887
citation:
ama: Korc F, Kolmogorov V, Lampert C. Approximating Marginals Using Discrete
Energy Minimization. IST Austria; 2012. doi:10.15479/AT:IST-2012-0003
apa: Korc, F., Kolmogorov, V., & Lampert, C. (2012). Approximating marginals
using discrete energy minimization. IST Austria. https://doi.org/10.15479/AT:IST-2012-0003
chicago: Korc, Filip, Vladimir Kolmogorov, and Christoph Lampert. Approximating
Marginals Using Discrete Energy Minimization. IST Austria, 2012. https://doi.org/10.15479/AT:IST-2012-0003.
ieee: F. Korc, V. Kolmogorov, and C. Lampert, Approximating marginals using discrete
energy minimization. IST Austria, 2012.
ista: Korc F, Kolmogorov V, Lampert C. 2012. Approximating marginals using discrete
energy minimization, IST Austria, 13p.
mla: Korc, Filip, et al. Approximating Marginals Using Discrete Energy Minimization.
IST Austria, 2012, doi:10.15479/AT:IST-2012-0003.
short: F. Korc, V. Kolmogorov, C. Lampert, Approximating Marginals Using Discrete
Energy Minimization, IST Austria, 2012.
date_created: 2018-12-12T11:39:06Z
date_published: 2012-07-23T00:00:00Z
date_updated: 2023-02-23T11:13:22Z
day: '23'
ddc:
- '000'
department:
- _id: VlKo
- _id: ChLa
doi: 10.15479/AT:IST-2012-0003
file:
- access_level: open_access
checksum: 7e0ba85ad123b13223aaf6cdde2d288c
content_type: application/pdf
creator: system
date_created: 2018-12-12T11:53:29Z
date_updated: 2020-07-14T12:46:44Z
file_id: '5490'
file_name: IST-2012-0003_IST-2012-0003.pdf
file_size: 618744
relation: main_file
file_date_updated: 2020-07-14T12:46:44Z
has_accepted_license: '1'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: '13'
publication_identifier:
issn:
- 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '36'
related_material:
record:
- id: '3124'
relation: earlier_version
status: public
status: public
title: Approximating marginals using discrete energy minimization
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2012'
...
---
_id: '5398'
abstract:
- lang: eng
text: This document is created as a part of the project “Repository for Research
Data on IST Austria”. It summarises the actual state of research data at IST Austria,
based on survey results. It supports the choice of appropriate software, which
would best fit the requirements of their users, the researchers.
author:
- first_name: Jana
full_name: Porsche, Jana
id: 3252EDC2-F248-11E8-B48F-1D18A9856A87
last_name: Porsche
citation:
ama: Porsche J. Actual State of Research Data @ ISTAustria. IST Austria;
2012.
apa: Porsche, J. (2012). Actual state of research data @ ISTAustria. IST
Austria.
chicago: Porsche, Jana. Actual State of Research Data @ ISTAustria. IST Austria,
2012.
ieee: J. Porsche, Actual state of research data @ ISTAustria. IST Austria,
2012.
ista: Porsche J. 2012. Actual state of research data @ ISTAustria, IST Austria,p.
mla: Porsche, Jana. Actual State of Research Data @ ISTAustria. IST Austria,
2012.
short: J. Porsche, Actual State of Research Data @ ISTAustria, IST Austria, 2012.
date_created: 2018-12-12T11:39:06Z
date_published: 2012-11-12T00:00:00Z
date_updated: 2020-07-14T23:04:49Z
day: '12'
ddc:
- '020'
department:
- _id: E-Lib
file:
- access_level: open_access
checksum: e0a7c041eea1ca4b70ab6f9ec5177f4e
content_type: application/pdf
creator: system
date_created: 2018-12-12T11:53:11Z
date_updated: 2020-07-14T12:46:44Z
file_id: '5472'
file_name: IST-2012-103-v1+1_Actual_state_of_research_data_@_IST_Austria.pdf
file_size: 238544
relation: main_file
file_date_updated: 2020-07-14T12:46:44Z
has_accepted_license: '1'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
publication_status: published
publisher: IST Austria
pubrep_id: '103'
status: public
title: Actual state of research data @ ISTAustria
type: report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2012'
...
---
_id: '5745'
article_processing_charge: No
author:
- first_name: Ashutosh
full_name: Gupta, Ashutosh
last_name: Gupta
citation:
ama: 'Gupta A. Improved Single Pass Algorithms for Resolution Proof Reduction. In:
Automated Technology for Verification and Analysis. Vol 7561. LNCS. Berlin,
Heidelberg: Springer Berlin Heidelberg; 2012:107-121. doi:10.1007/978-3-642-33386-6_10'
apa: 'Gupta, A. (2012). Improved Single Pass Algorithms for Resolution Proof Reduction.
In Automated Technology for Verification and Analysis (Vol. 7561, pp. 107–121).
Berlin, Heidelberg: Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-642-33386-6_10'
chicago: 'Gupta, Ashutosh. “Improved Single Pass Algorithms for Resolution Proof
Reduction.” In Automated Technology for Verification and Analysis, 7561:107–21.
LNCS. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. https://doi.org/10.1007/978-3-642-33386-6_10.'
ieee: 'A. Gupta, “Improved Single Pass Algorithms for Resolution Proof Reduction,”
in Automated Technology for Verification and Analysis, vol. 7561, Berlin,
Heidelberg: Springer Berlin Heidelberg, 2012, pp. 107–121.'
ista: 'Gupta A. 2012.Improved Single Pass Algorithms for Resolution Proof Reduction.
In: Automated Technology for Verification and Analysis. vol. 7561, 107–121.'
mla: Gupta, Ashutosh. “Improved Single Pass Algorithms for Resolution Proof Reduction.”
Automated Technology for Verification and Analysis, vol. 7561, Springer
Berlin Heidelberg, 2012, pp. 107–21, doi:10.1007/978-3-642-33386-6_10.
short: A. Gupta, in:, Automated Technology for Verification and Analysis, Springer
Berlin Heidelberg, Berlin, Heidelberg, 2012, pp. 107–121.
conference:
end_date: 2012-10-06
location: Thiruvananthapuram, Kerala, India
name: ATVA 2012
start_date: 2012-10-03
date_created: 2018-12-18T13:01:46Z
date_published: 2012-01-01T00:00:00Z
date_updated: 2023-09-05T14:15:29Z
ddc:
- '005'
department:
- _id: ToHe
doi: 10.1007/978-3-642-33386-6_10
ec_funded: 1
file:
- access_level: open_access
checksum: 68415837a315de3cc4d120f6019d752c
content_type: application/pdf
creator: dernst
date_created: 2018-12-18T13:07:35Z
date_updated: 2020-07-14T12:47:10Z
file_id: '5746'
file_name: 2012_ATVA_Gupta.pdf
file_size: 465502
relation: main_file
file_date_updated: 2020-07-14T12:47:10Z
has_accepted_license: '1'
intvolume: ' 7561'
language:
- iso: eng
oa: 1
oa_version: None
page: 107-121
place: Berlin, Heidelberg
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
publication: Automated Technology for Verification and Analysis
publication_identifier:
eissn:
- 1611-3349
isbn:
- '9783642333859'
- '9783642333866'
issn:
- 0302-9743
publication_status: published
publisher: Springer Berlin Heidelberg
pubrep_id: '180'
quality_controlled: '1'
series_title: LNCS
status: public
title: Improved Single Pass Algorithms for Resolution Proof Reduction
type: book_chapter
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 7561
year: '2012'
...
---
_id: '5839'
abstract:
- lang: eng
text: "Canny's edge detection algorithm is a classical and robust method for edge
detection in gray-scale images. The two \r\nsignificant features of this method
are introduction of NMS (Non-Maximum Suppression) and double thresholding of \r\nthe
\ gradient image. Due to poor illumination, the region boundaries in
\ an image may become vague, creating \r\nuncertainties in the gradient
\ image. In this paper, we have proposed an algorithm based on the
\ concept of type-2 fuzzy sets to handle uncertainties that automatically
\ selects the threshold values needed to segment the gradient image using
classical Canny’s edge detection algorithm. The results show that our algorithm
works significantly well on different benchmark images as well as medical images
(hand radiography images). "
author:
- first_name: Ranita
full_name: Biswas, Ranita
id: 3C2B033E-F248-11E8-B48F-1D18A9856A87
last_name: Biswas
orcid: 0000-0002-5372-7890
- first_name: Jaya
full_name: Sil, Jaya
last_name: Sil
citation:
ama: Biswas R, Sil J. An Improved Canny Edge Detection Algorithm Based on Type-2
Fuzzy Sets. Procedia Technology. 2012;4:820-824. doi:10.1016/j.protcy.2012.05.134
apa: Biswas, R., & Sil, J. (2012). An Improved Canny Edge Detection Algorithm
Based on Type-2 Fuzzy Sets. Procedia Technology. Elsevier. https://doi.org/10.1016/j.protcy.2012.05.134
chicago: Biswas, Ranita, and Jaya Sil. “An Improved Canny Edge Detection Algorithm
Based on Type-2 Fuzzy Sets.” Procedia Technology. Elsevier, 2012. https://doi.org/10.1016/j.protcy.2012.05.134.
ieee: R. Biswas and J. Sil, “An Improved Canny Edge Detection Algorithm Based on
Type-2 Fuzzy Sets,” Procedia Technology, vol. 4. Elsevier, pp. 820–824,
2012.
ista: Biswas R, Sil J. 2012. An Improved Canny Edge Detection Algorithm Based on
Type-2 Fuzzy Sets. Procedia Technology. 4, 820–824.
mla: Biswas, Ranita, and Jaya Sil. “An Improved Canny Edge Detection Algorithm Based
on Type-2 Fuzzy Sets.” Procedia Technology, vol. 4, Elsevier, 2012, pp.
820–24, doi:10.1016/j.protcy.2012.05.134.
short: R. Biswas, J. Sil, Procedia Technology 4 (2012) 820–824.
date_created: 2019-01-17T11:54:21Z
date_published: 2012-05-01T00:00:00Z
date_updated: 2021-01-12T08:03:43Z
day: '01'
ddc:
- '000'
doi: 10.1016/j.protcy.2012.05.134
extern: '1'
file:
- access_level: open_access
checksum: ba0185986b151d8c11201f48cd505ceb
content_type: application/pdf
creator: dernst
date_created: 2019-01-21T07:28:06Z
date_updated: 2020-07-14T12:47:12Z
file_id: '5863'
file_name: 2012_Procedia_Biswas.pdf
file_size: 305426
relation: main_file
file_date_updated: 2020-07-14T12:47:12Z
has_accepted_license: '1'
intvolume: ' 4'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: 820-824
publication: Procedia Technology
publication_identifier:
issn:
- 2212-0173
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: An Improved Canny Edge Detection Algorithm Based on Type-2 Fuzzy Sets
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 4
year: '2012'
...
---
_id: '596'
abstract:
- lang: eng
text: The human Mediator complex controls RNA polymerase II (pol II) function in
ways that remain incompletely understood. Activator-Mediator binding alters Mediator
structure, and these activator-induced structural shifts appear to play key roles
in regulating transcription. A recent cryo-electron microscopy (EM) analysis revealed
that pol II adopted a stable orientation within a Mediator-pol II-TFIIF assembly
in which Mediator was bound to the activation domain of viral protein 16 (VP16).
Whereas TFIIF was shown to be important for orienting pol II within this assembly,
the potential role of the activator was not assessed. To determine how activator
binding might affect pol II orientation, we isolated human Mediator-pol II-TFIIF
complexes in which Mediator was not bound to an activator. Cryo-EM analysis of
this assembly, coupled with pol II crystal structure docking, revealed that pol
II binds Mediator at the same general location; however, in contrast to VP16-bound
Mediator, pol II does not appear to stably orient in the absence of an activator.
Variability in pol II orientation might be important mechanistically, perhaps
to enable sense and antisense transcription at human promoters. Because Mediator
interacts extensively with pol II, these results suggest that Mediator structural
shifts induced by activator binding help stably orient pol II prior to transcription
initiation.
article_processing_charge: No
author:
- first_name: Carrie A
full_name: Bernecky, Carrie A
id: 2CB9DFE2-F248-11E8-B48F-1D18A9856A87
last_name: Bernecky
orcid: 0000-0003-0893-7036
- first_name: Dylan
full_name: Taatjes, Dylan
last_name: Taatjes
citation:
ama: Bernecky C, Taatjes D. Activator-mediator binding stabilizes RNA polymerase
II orientation within the human mediator-RNA polymerase II-TFIIF assembly. Journal
of Molecular Biology. 2012;417(5):387-394. doi:10.1016/j.jmb.2012.02.014
apa: Bernecky, C., & Taatjes, D. (2012). Activator-mediator binding stabilizes
RNA polymerase II orientation within the human mediator-RNA polymerase II-TFIIF
assembly. Journal of Molecular Biology. Elsevier. https://doi.org/10.1016/j.jmb.2012.02.014
chicago: Bernecky, Carrie, and Dylan Taatjes. “Activator-Mediator Binding Stabilizes
RNA Polymerase II Orientation within the Human Mediator-RNA Polymerase II-TFIIF
Assembly.” Journal of Molecular Biology. Elsevier, 2012. https://doi.org/10.1016/j.jmb.2012.02.014.
ieee: C. Bernecky and D. Taatjes, “Activator-mediator binding stabilizes RNA polymerase
II orientation within the human mediator-RNA polymerase II-TFIIF assembly,” Journal
of Molecular Biology, vol. 417, no. 5. Elsevier, pp. 387–394, 2012.
ista: Bernecky C, Taatjes D. 2012. Activator-mediator binding stabilizes RNA polymerase
II orientation within the human mediator-RNA polymerase II-TFIIF assembly. Journal
of Molecular Biology. 417(5), 387–394.
mla: Bernecky, Carrie, and Dylan Taatjes. “Activator-Mediator Binding Stabilizes
RNA Polymerase II Orientation within the Human Mediator-RNA Polymerase II-TFIIF
Assembly.” Journal of Molecular Biology, vol. 417, no. 5, Elsevier, 2012,
pp. 387–94, doi:10.1016/j.jmb.2012.02.014.
short: C. Bernecky, D. Taatjes, Journal of Molecular Biology 417 (2012) 387–394.
date_created: 2018-12-11T11:47:24Z
date_published: 2012-04-13T00:00:00Z
date_updated: 2021-01-12T08:05:21Z
day: '13'
doi: 10.1016/j.jmb.2012.02.014
extern: '1'
intvolume: ' 417'
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582759/
month: '04'
oa: 1
oa_version: None
page: 387 - 394
publication: Journal of Molecular Biology
publication_status: published
publisher: Elsevier
publist_id: '7208'
status: public
title: Activator-mediator binding stabilizes RNA polymerase II orientation within
the human mediator-RNA polymerase II-TFIIF assembly
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 417
year: '2012'
...
---
_id: '6136'
abstract:
- lang: eng
text: Tonic receptors convey stimulus duration and intensity and are implicated
in homeostatic control. However, how tonic homeostatic signals are generated and
how they reconfigure neural circuits and modify animal behavior is poorly understood.
Here we show that Caenorhabditis elegans O2-sensing neurons are tonic receptors
that continuously signal ambient [O2] to set the animal's behavioral state. Sustained
signaling relied on a Ca2+ relay involving L-type voltage-gated Ca2+ channels,
the ryanodine and the inositol-1,4,5-trisphosphate receptors. Tonic activity evoked
continuous neuropeptide release, which helps elicit the enduring behavioral state
associated with high [O2]. Sustained O2 receptor signaling was propagated to downstream
neural circuits, including the hub interneuron RMG. O2 receptors evoked similar
locomotory states at particular O2 concentrations, regardless of previous d[O2]/dt.
However, a phasic component of the URX receptors' response to high d[O2]/dt, as
well as tonic-to-phasic transformations in downstream interneurons, enabled transient
reorientation movements shaped by d[O2]/dt. Our results highlight how tonic homeostatic
signals can generate both transient and enduring behavioral change.
author:
- first_name: Karl Emanuel
full_name: Busch, Karl Emanuel
last_name: Busch
- first_name: Patrick
full_name: Laurent, Patrick
last_name: Laurent
- first_name: Zoltan
full_name: Soltesz, Zoltan
last_name: Soltesz
- first_name: Robin Joseph
full_name: Murphy, Robin Joseph
last_name: Murphy
- first_name: Olivier
full_name: Faivre, Olivier
last_name: Faivre
- first_name: Berthold
full_name: Hedwig, Berthold
last_name: Hedwig
- first_name: Martin
full_name: Thomas, Martin
last_name: Thomas
- first_name: Heather L
full_name: Smith, Heather L
last_name: Smith
- first_name: Mario
full_name: de Bono, Mario
id: 4E3FF80E-F248-11E8-B48F-1D18A9856A87
last_name: de Bono
orcid: 0000-0001-8347-0443
citation:
ama: Busch KE, Laurent P, Soltesz Z, et al. Tonic signaling from O2 sensors sets
neural circuit activity and behavioral state. Nature Neuroscience. 2012;15(4):581-591.
doi:10.1038/nn.3061
apa: Busch, K. E., Laurent, P., Soltesz, Z., Murphy, R. J., Faivre, O., Hedwig,
B., … de Bono, M. (2012). Tonic signaling from O2 sensors sets neural circuit
activity and behavioral state. Nature Neuroscience. Springer Nature. https://doi.org/10.1038/nn.3061
chicago: Busch, Karl Emanuel, Patrick Laurent, Zoltan Soltesz, Robin Joseph Murphy,
Olivier Faivre, Berthold Hedwig, Martin Thomas, Heather L Smith, and Mario de
Bono. “Tonic Signaling from O2 Sensors Sets Neural Circuit Activity and Behavioral
State.” Nature Neuroscience. Springer Nature, 2012. https://doi.org/10.1038/nn.3061.
ieee: K. E. Busch et al., “Tonic signaling from O2 sensors sets neural circuit
activity and behavioral state,” Nature Neuroscience, vol. 15, no. 4. Springer
Nature, pp. 581–591, 2012.
ista: Busch KE, Laurent P, Soltesz Z, Murphy RJ, Faivre O, Hedwig B, Thomas M, Smith
HL, de Bono M. 2012. Tonic signaling from O2 sensors sets neural circuit activity
and behavioral state. Nature Neuroscience. 15(4), 581–591.
mla: Busch, Karl Emanuel, et al. “Tonic Signaling from O2 Sensors Sets Neural Circuit
Activity and Behavioral State.” Nature Neuroscience, vol. 15, no. 4, Springer
Nature, 2012, pp. 581–91, doi:10.1038/nn.3061.
short: K.E. Busch, P. Laurent, Z. Soltesz, R.J. Murphy, O. Faivre, B. Hedwig, M.
Thomas, H.L. Smith, M. de Bono, Nature Neuroscience 15 (2012) 581–591.
date_created: 2019-03-20T14:23:30Z
date_published: 2012-03-04T00:00:00Z
date_updated: 2021-01-12T08:06:17Z
day: '04'
doi: 10.1038/nn.3061
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publication_identifier:
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publisher: Springer Nature
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title: Tonic signaling from O2 sensors sets neural circuit activity and behavioral
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volume: 15
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...