---
_id: '11870'
abstract:
- lang: eng
text: "We consider dynamic algorithms for maintaining Single-Source Reachability
(SSR) and approximate Single-Source Shortest Paths (SSSP) on n-node m-edge directed
graphs under edge deletions (decremental algorithms). The previous fastest algorithm
for SSR and SSSP goes back three decades to Even and Shiloach (JACM 1981); it
has O(1) query time and O(mn) total update time (i.e., linear amortized update
time if all edges are deleted). This algorithm serves as a building block for
several other dynamic algorithms. The question whether its total update time can
be improved is a major, long standing, open problem.\r\n\r\nIn this paper, we
answer this question affirmatively. We obtain a randomized algorithm which, in
a simplified form, achieves an Õ(mn0.984) expected total update time for SSR and
(1 + ε)-approximate SSSP, where Õ(·) hides poly log n. We also extend our algorithm
to achieve roughly the same running time for Strongly Connected Components (SCC),
improving the algorithm of Roditty and Zwick (FOCS 2002), and an algorithm that
improves the Õ (mn log W)-time algorithm of Bernstein (STOC 2013) for approximating
SSSP on weighted directed graphs, where the edge weights are integers from 1 to
W. All our algorithms have constant query time in the worst case."
article_number: 674 - 683
article_processing_charge: No
arxiv: 1
author:
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
- first_name: Sebastian
full_name: Krinninger, Sebastian
last_name: Krinninger
- first_name: Danupon
full_name: Nanongkai, Danupon
last_name: Nanongkai
citation:
ama: 'Henzinger MH, Krinninger S, Nanongkai D. Sublinear-time decremental algorithms
for single-source reachability and shortest paths on directed graphs. In: 46th
Annual ACM Symposium on Theory of Computing. Association for Computing Machinery;
2014. doi:10.1145/2591796.2591869'
apa: 'Henzinger, M. H., Krinninger, S., & Nanongkai, D. (2014). Sublinear-time
decremental algorithms for single-source reachability and shortest paths on directed
graphs. In 46th Annual ACM Symposium on Theory of Computing. New York,
NY, United States: Association for Computing Machinery. https://doi.org/10.1145/2591796.2591869'
chicago: Henzinger, Monika H, Sebastian Krinninger, and Danupon Nanongkai. “Sublinear-Time
Decremental Algorithms for Single-Source Reachability and Shortest Paths on Directed
Graphs.” In 46th Annual ACM Symposium on Theory of Computing. Association
for Computing Machinery, 2014. https://doi.org/10.1145/2591796.2591869.
ieee: M. H. Henzinger, S. Krinninger, and D. Nanongkai, “Sublinear-time decremental
algorithms for single-source reachability and shortest paths on directed graphs,”
in 46th Annual ACM Symposium on Theory of Computing, New York, NY, United
States, 2014.
ista: 'Henzinger MH, Krinninger S, Nanongkai D. 2014. Sublinear-time decremental
algorithms for single-source reachability and shortest paths on directed graphs.
46th Annual ACM Symposium on Theory of Computing. STOC: Symposium on Theory of
Computing, 674–683.'
mla: Henzinger, Monika H., et al. “Sublinear-Time Decremental Algorithms for Single-Source
Reachability and Shortest Paths on Directed Graphs.” 46th Annual ACM Symposium
on Theory of Computing, 674–683, Association for Computing Machinery, 2014,
doi:10.1145/2591796.2591869.
short: M.H. Henzinger, S. Krinninger, D. Nanongkai, in:, 46th Annual ACM Symposium
on Theory of Computing, Association for Computing Machinery, 2014.
conference:
end_date: 2014-06-03
location: New York, NY, United States
name: 'STOC: Symposium on Theory of Computing'
start_date: 2014-05-31
date_created: 2022-08-16T09:41:57Z
date_published: 2014-05-01T00:00:00Z
date_updated: 2023-02-17T11:18:52Z
day: '01'
doi: 10.1145/2591796.2591869
extern: '1'
external_id:
arxiv:
- '1504.07959'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1504.07959
month: '05'
oa: 1
oa_version: Preprint
publication: 46th Annual ACM Symposium on Theory of Computing
publication_identifier:
isbn:
- 978-145032710-7
issn:
- 0737-8017
publication_status: published
publisher: Association for Computing Machinery
quality_controlled: '1'
scopus_import: '1'
status: public
title: Sublinear-time decremental algorithms for single-source reachability and shortest
paths on directed graphs
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2014'
...
---
_id: '11875'
abstract:
- lang: eng
text: We present the first deterministic data structures for maintaining approximate
minimum vertex cover and maximum matching in a fully dynamic graph in time per
update. In particular, for minimum vertex cover we provide deterministic data
structures for maintaining a (2 + ε) approximation in O(log n/ε2) amortized time
per update. For maximum matching, we show how to maintain a (3 + e) approximation
in O(m1/3/ε2) amortized time per update, and a (4 + ε) approximation in O(m1/3/ε2)
worst-case time per update. Our data structure for fully dynamic minimum vertex
cover is essentially near-optimal and settles an open problem by Onak and Rubinfeld
[13].
article_processing_charge: No
arxiv: 1
author:
- first_name: Sayan
full_name: Bhattacharya, Sayan
last_name: Bhattacharya
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
- first_name: Giuseppe F.
full_name: Italiano, Giuseppe F.
last_name: Italiano
citation:
ama: 'Bhattacharya S, Henzinger MH, Italiano GF. Deterministic fully dynamic data
structures for vertex cover and matching. In: 26th Annual ACM-SIAM Symposium
on Discrete Algorithms. Society for Industrial and Applied Mathematics; 2014:785-804.
doi:10.1137/1.9781611973730.54'
apa: 'Bhattacharya, S., Henzinger, M. H., & Italiano, G. F. (2014). Deterministic
fully dynamic data structures for vertex cover and matching. In 26th Annual
ACM-SIAM Symposium on Discrete Algorithms (pp. 785–804). San Diego, CA, United
States: Society for Industrial and Applied Mathematics. https://doi.org/10.1137/1.9781611973730.54'
chicago: Bhattacharya, Sayan, Monika H Henzinger, and Giuseppe F. Italiano. “Deterministic
Fully Dynamic Data Structures for Vertex Cover and Matching.” In 26th Annual
ACM-SIAM Symposium on Discrete Algorithms, 785–804. Society for Industrial
and Applied Mathematics, 2014. https://doi.org/10.1137/1.9781611973730.54.
ieee: S. Bhattacharya, M. H. Henzinger, and G. F. Italiano, “Deterministic fully
dynamic data structures for vertex cover and matching,” in 26th Annual ACM-SIAM
Symposium on Discrete Algorithms, San Diego, CA, United States, 2014, pp.
785–804.
ista: 'Bhattacharya S, Henzinger MH, Italiano GF. 2014. Deterministic fully dynamic
data structures for vertex cover and matching. 26th Annual ACM-SIAM Symposium
on Discrete Algorithms. SODA: Symposium on Discrete Algorithms, 785–804.'
mla: Bhattacharya, Sayan, et al. “Deterministic Fully Dynamic Data Structures for
Vertex Cover and Matching.” 26th Annual ACM-SIAM Symposium on Discrete Algorithms,
Society for Industrial and Applied Mathematics, 2014, pp. 785–804, doi:10.1137/1.9781611973730.54.
short: S. Bhattacharya, M.H. Henzinger, G.F. Italiano, in:, 26th Annual ACM-SIAM
Symposium on Discrete Algorithms, Society for Industrial and Applied Mathematics,
2014, pp. 785–804.
conference:
end_date: 2015-01-06
location: San Diego, CA, United States
name: 'SODA: Symposium on Discrete Algorithms'
start_date: 2015-01-04
date_created: 2022-08-16T12:36:42Z
date_published: 2014-01-01T00:00:00Z
date_updated: 2023-02-21T16:32:06Z
day: '01'
doi: 10.1137/1.9781611973730.54
extern: '1'
external_id:
arxiv:
- '1412.1318'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1412.1318
month: '01'
oa: 1
oa_version: Preprint
page: 785-804
publication: 26th Annual ACM-SIAM Symposium on Discrete Algorithms
publication_identifier:
eisbn:
- 978-1-61197-373-0
isbn:
- 978-1-61197-374-7
publication_status: published
publisher: Society for Industrial and Applied Mathematics
quality_controlled: '1'
related_material:
record:
- id: '11890'
relation: later_version
status: public
scopus_import: '1'
status: public
title: Deterministic fully dynamic data structures for vertex cover and matching
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2014'
...
---
_id: '11876'
abstract:
- lang: eng
text: "We study dynamic (1 + ∊)-approximation algorithms for the single-source shortest
paths problem in an unweighted undirected n-node m-edge graph under edge deletions.
The fastest algorithm for this problem is an algorithm with O(n2+o(1)) total update
time and constant query time by Bernstein and Roditty (SODA 2011). In this paper,
we improve the total update time to O(n1.8+o(1) + m1+o(1)) while keeping the query
time constant. This running time is essentially tight when m = Ω(n1.8) since we
need Ω(m) time even in the static setting. For smaller values of m, the running
time of our algorithm is subquadratic, and is the first that breaks through the
quadratic time barrier.\r\n\r\nIn obtaining this result, we develop a fast algorithm
for what we call center cover data structure. We also make non-trivial extensions
to our previous techniques called lazy-update and monotone Even-Shiloach trees
(ICALP 2013 and FOCS 2013). As by-products of our new techniques, we obtain two
new results for the decremental all-pairs shortest-paths problem. Our first result
is the first approximation algorithm whose total update time is faster than Õ(mn)
for all values of m. Our second result is a new trade-off between the total update
time and the additive approximation guarantee."
article_processing_charge: No
author:
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
- first_name: Sebastian
full_name: Krinninger, Sebastian
last_name: Krinninger
- first_name: Danupon
full_name: Nanongkai, Danupon
last_name: Nanongkai
citation:
ama: 'Henzinger MH, Krinninger S, Nanongkai D. A subquadratic-time algorithm for
decremental single-source shortest paths. In: 25th Annual ACM-SIAM Symposium
on Discrete Algorithms. Society for Industrial and Applied Mathematics; 2014:1053-1072.
doi:10.1137/1.9781611973402.79'
apa: 'Henzinger, M. H., Krinninger, S., & Nanongkai, D. (2014). A subquadratic-time
algorithm for decremental single-source shortest paths. In 25th Annual ACM-SIAM
Symposium on Discrete Algorithms (pp. 1053–1072). Portland, OR, United States:
Society for Industrial and Applied Mathematics. https://doi.org/10.1137/1.9781611973402.79'
chicago: Henzinger, Monika H, Sebastian Krinninger, and Danupon Nanongkai. “A Subquadratic-Time
Algorithm for Decremental Single-Source Shortest Paths.” In 25th Annual ACM-SIAM
Symposium on Discrete Algorithms, 1053–72. Society for Industrial and Applied
Mathematics, 2014. https://doi.org/10.1137/1.9781611973402.79.
ieee: M. H. Henzinger, S. Krinninger, and D. Nanongkai, “A subquadratic-time algorithm
for decremental single-source shortest paths,” in 25th Annual ACM-SIAM Symposium
on Discrete Algorithms, Portland, OR, United States, 2014, pp. 1053–1072.
ista: 'Henzinger MH, Krinninger S, Nanongkai D. 2014. A subquadratic-time algorithm
for decremental single-source shortest paths. 25th Annual ACM-SIAM Symposium on
Discrete Algorithms. SODA: Symposium on Discrete Algorithms, 1053–1072.'
mla: Henzinger, Monika H., et al. “A Subquadratic-Time Algorithm for Decremental
Single-Source Shortest Paths.” 25th Annual ACM-SIAM Symposium on Discrete Algorithms,
Society for Industrial and Applied Mathematics, 2014, pp. 1053–72, doi:10.1137/1.9781611973402.79.
short: M.H. Henzinger, S. Krinninger, D. Nanongkai, in:, 25th Annual ACM-SIAM Symposium
on Discrete Algorithms, Society for Industrial and Applied Mathematics, 2014,
pp. 1053–1072.
conference:
end_date: 2014-01-07
location: Portland, OR, United States
name: 'SODA: Symposium on Discrete Algorithms'
start_date: 2014-01-05
date_created: 2022-08-16T12:58:31Z
date_published: 2014-01-01T00:00:00Z
date_updated: 2023-02-17T11:58:42Z
day: '01'
doi: 10.1137/1.9781611973402.79
extern: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1137/1.9781611973402.79
month: '01'
oa: 1
oa_version: Published Version
page: 1053-1072
publication: 25th Annual ACM-SIAM Symposium on Discrete Algorithms
publication_identifier:
eisbn:
- 978-1-61197-340-2
isbn:
- 978-1-61197-338-9
publication_status: published
publisher: Society for Industrial and Applied Mathematics
quality_controlled: '1'
scopus_import: '1'
status: public
title: A subquadratic-time algorithm for decremental single-source shortest paths
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2014'
...
---
_id: '119'
abstract:
- lang: eng
text: Observations of flowing granular matter have suggested that same-material
tribocharging depends on particle size, typically rendering large grains positive
and small ones negative. Models assuming the transfer of trapped electrons can
account for this trend, but have not been validated. Tracking individual grains
in an electric field, we show quantitatively that charge is transferred based
on size between materially identical grains. However, the surface density of trapped
electrons, measured independently by thermoluminescence techniques, is orders
of magnitude too small to account for the scale of charge transferred. This reveals
that trapped electrons are not a necessary ingredient for same-material tribocharging.
acknowledgement: This work was supported by the NSF through DMR-1309611. Access to
the shared experimental facilities provided by the NSF-supported Chicago MRSEC (DMR-0820054)
is gratefully acknowledged. S. L. F. and J. L. P. acknowledge funding from UIC NSF
Grants No. 0850830 and No. 0602308. S. R. W. acknowledges support from a University
of Chicago Millikan Fellowship and from Mrs. Joan Winstein through the Winstein
Prize for Instrumentation.
article_number: '218001'
arxiv: 1
author:
- first_name: Scott R
full_name: Waitukaitis, Scott R
id: 3A1FFC16-F248-11E8-B48F-1D18A9856A87
last_name: Waitukaitis
orcid: 0000-0002-2299-3176
- first_name: Victor
full_name: Lee, Victor
last_name: Lee
- first_name: James
full_name: Pierson, James
last_name: Pierson
- first_name: Steven
full_name: Forman, Steven
last_name: Forman
- first_name: Heinrich
full_name: Jaeger, Heinrich
last_name: Jaeger
citation:
ama: Waitukaitis SR, Lee V, Pierson J, Forman S, Jaeger H. Size-dependent same-material
tribocharging in insulating grains. APS Physics, Physical Review Letters.
2014;112(21). doi:10.1103/PhysRevLett.112.218001
apa: Waitukaitis, S. R., Lee, V., Pierson, J., Forman, S., & Jaeger, H. (2014).
Size-dependent same-material tribocharging in insulating grains. APS Physics,
Physical Review Letters. American Physical Society. https://doi.org/10.1103/PhysRevLett.112.218001
chicago: Waitukaitis, Scott R, Victor Lee, James Pierson, Steven Forman, and Heinrich
Jaeger. “Size-Dependent Same-Material Tribocharging in Insulating Grains.” APS
Physics, Physical Review Letters. American Physical Society, 2014. https://doi.org/10.1103/PhysRevLett.112.218001.
ieee: S. R. Waitukaitis, V. Lee, J. Pierson, S. Forman, and H. Jaeger, “Size-dependent
same-material tribocharging in insulating grains,” APS Physics, Physical Review
Letters, vol. 112, no. 21. American Physical Society, 2014.
ista: Waitukaitis SR, Lee V, Pierson J, Forman S, Jaeger H. 2014. Size-dependent
same-material tribocharging in insulating grains. APS Physics, Physical Review
Letters. 112(21), 218001.
mla: Waitukaitis, Scott R., et al. “Size-Dependent Same-Material Tribocharging in
Insulating Grains.” APS Physics, Physical Review Letters, vol. 112, no.
21, 218001, American Physical Society, 2014, doi:10.1103/PhysRevLett.112.218001.
short: S.R. Waitukaitis, V. Lee, J. Pierson, S. Forman, H. Jaeger, APS Physics,
Physical Review Letters 112 (2014).
date_created: 2018-12-11T11:44:44Z
date_published: 2014-05-30T00:00:00Z
date_updated: 2021-01-12T06:48:58Z
day: '30'
doi: 10.1103/PhysRevLett.112.218001
extern: '1'
external_id:
arxiv:
- '1309.2578'
intvolume: ' 112'
issue: '21'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1309.2578
month: '05'
oa: 1
oa_version: Submitted Version
publication: APS Physics, Physical Review Letters
publication_status: published
publisher: American Physical Society
publist_id: '7935'
quality_controlled: '1'
status: public
title: Size-dependent same-material tribocharging in insulating grains
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 112
year: '2014'
...
---
_id: '11967'
abstract:
- lang: eng
text: An experimentally easy to perform method for the generation of alumina-supported
Fe3O4 nanoparticles [(6±1) nm size, 0.67 wt %]and the use of this material in
hydrazine-mediated heterogeneously catalyzed reductions of nitroarenes to anilines
under batch and continuous-flow conditions is presented. The bench-stable, reusable
nano-Fe3O4@Al2O3 catalyst can selectively reduce functionalized nitroarenes at
1 mol % catalyst loading by using a 20 mol % excess of hydrazine hydrate in an
elevated temperature regime (150 °C, reaction time 2–6 min in batch). For continuous-flow
processing, the catalyst material is packed into dedicated cartridges and used
in a commercially available high-temperature/-pressure flow device. In continuous
mode, reaction times can be reduced to less than 1 min at 150 °C (30 bar back
pressure) in a highly intensified process. The nano-Fe3O4@Al2O3 catalyst demonstrated
stable reduction of nitrobenzene (0.5 M in MeOH) for more than 10 h on stream
at a productivity of 30 mmol h−1 (0.72 mol per day). Importantly, virtually no
leaching of the catalytically active material could be observed by inductively
coupled plasma MS monitoring.
article_processing_charge: No
article_type: original
author:
- first_name: Mojtaba Mirhosseini
full_name: Moghaddam, Mojtaba Mirhosseini
last_name: Moghaddam
- first_name: Bartholomäus
full_name: Pieber, Bartholomäus
id: 93e5e5b2-0da6-11ed-8a41-af589a024726
last_name: Pieber
orcid: 0000-0001-8689-388X
- first_name: Toma
full_name: Glasnov, Toma
last_name: Glasnov
- first_name: C. Oliver
full_name: Kappe, C. Oliver
last_name: Kappe
citation:
ama: Moghaddam MM, Pieber B, Glasnov T, Kappe CO. Immobilized iron oxide nanoparticles
as stable and reusable catalysts for hydrazine-mediated nitro reductions in continuous
flow. ChemSusChem. 2014;7(11):3122-3131. doi:10.1002/cssc.201402455
apa: Moghaddam, M. M., Pieber, B., Glasnov, T., & Kappe, C. O. (2014). Immobilized
iron oxide nanoparticles as stable and reusable catalysts for hydrazine-mediated
nitro reductions in continuous flow. ChemSusChem. Wiley. https://doi.org/10.1002/cssc.201402455
chicago: Moghaddam, Mojtaba Mirhosseini, Bartholomäus Pieber, Toma Glasnov, and
C. Oliver Kappe. “Immobilized Iron Oxide Nanoparticles as Stable and Reusable
Catalysts for Hydrazine-Mediated Nitro Reductions in Continuous Flow.” ChemSusChem.
Wiley, 2014. https://doi.org/10.1002/cssc.201402455.
ieee: M. M. Moghaddam, B. Pieber, T. Glasnov, and C. O. Kappe, “Immobilized iron
oxide nanoparticles as stable and reusable catalysts for hydrazine-mediated nitro
reductions in continuous flow,” ChemSusChem, vol. 7, no. 11. Wiley, pp.
3122–3131, 2014.
ista: Moghaddam MM, Pieber B, Glasnov T, Kappe CO. 2014. Immobilized iron oxide
nanoparticles as stable and reusable catalysts for hydrazine-mediated nitro reductions
in continuous flow. ChemSusChem. 7(11), 3122–3131.
mla: Moghaddam, Mojtaba Mirhosseini, et al. “Immobilized Iron Oxide Nanoparticles
as Stable and Reusable Catalysts for Hydrazine-Mediated Nitro Reductions in Continuous
Flow.” ChemSusChem, vol. 7, no. 11, Wiley, 2014, pp. 3122–31, doi:10.1002/cssc.201402455.
short: M.M. Moghaddam, B. Pieber, T. Glasnov, C.O. Kappe, ChemSusChem 7 (2014) 3122–3131.
date_created: 2022-08-25T08:36:54Z
date_published: 2014-11-01T00:00:00Z
date_updated: 2023-02-21T10:09:42Z
day: '01'
doi: 10.1002/cssc.201402455
extern: '1'
external_id:
pmid:
- '25209099'
intvolume: ' 7'
issue: '11'
language:
- iso: eng
month: '11'
oa_version: None
page: 3122-3131
pmid: 1
publication: ChemSusChem
publication_identifier:
eissn:
- 1864-564X
issn:
- 1864-5631
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Immobilized iron oxide nanoparticles as stable and reusable catalysts for hydrazine-mediated
nitro reductions in continuous flow
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2014'
...
---
_id: '11968'
abstract:
- lang: eng
text: 'Membrane phospholipids typically contain fatty acids (FAs) of 16 and 18 carbon
atoms. This particular chain length is evolutionarily highly conserved and presumably
provides maximum stability and dynamic properties to biological membranes in response
to nutritional or environmental cues. Here, we show that the relative proportion
of C16 versus C18 FAs is regulated by the activity of acetyl-CoA carboxylase (Acc1),
the first and rate-limiting enzyme of FA de novo synthesis. Acc1 activity is attenuated
by AMPK/Snf1-dependent phosphorylation, which is required to maintain an appropriate
acyl-chain length distribution. Moreover, we find that the transcriptional repressor
Opi1 preferentially binds to C16 over C18 phosphatidic acid (PA) species: thus,
C16-chain containing PA sequesters Opi1 more effectively to the ER, enabling AMPK/Snf1
control of PA acyl-chain length to determine the degree of derepression of Opi1
target genes. These findings reveal an unexpected regulatory link between the
major energy-sensing kinase, membrane lipid composition, and transcription.'
article_processing_charge: No
article_type: original
author:
- first_name: Harald F.
full_name: Hofbauer, Harald F.
last_name: Hofbauer
- first_name: Florian H.
full_name: Schopf, Florian H.
last_name: Schopf
- first_name: Hannes
full_name: Schleifer, Hannes
last_name: Schleifer
- first_name: Oskar L.
full_name: Knittelfelder, Oskar L.
last_name: Knittelfelder
- first_name: Bartholomäus
full_name: Pieber, Bartholomäus
id: 93e5e5b2-0da6-11ed-8a41-af589a024726
last_name: Pieber
orcid: 0000-0001-8689-388X
- first_name: Gerald N.
full_name: Rechberger, Gerald N.
last_name: Rechberger
- first_name: Heimo
full_name: Wolinski, Heimo
last_name: Wolinski
- first_name: Maria L.
full_name: Gaspar, Maria L.
last_name: Gaspar
- first_name: C. Oliver
full_name: Kappe, C. Oliver
last_name: Kappe
- first_name: Johannes
full_name: Stadlmann, Johannes
last_name: Stadlmann
- first_name: Karl
full_name: Mechtler, Karl
last_name: Mechtler
- first_name: Alexandra
full_name: Zenz, Alexandra
last_name: Zenz
- first_name: Karl
full_name: Lohner, Karl
last_name: Lohner
- first_name: Oksana
full_name: Tehlivets, Oksana
last_name: Tehlivets
- first_name: Susan A.
full_name: Henry, Susan A.
last_name: Henry
- first_name: Sepp D.
full_name: Kohlwein, Sepp D.
last_name: Kohlwein
citation:
ama: Hofbauer HF, Schopf FH, Schleifer H, et al. Regulation of gene expression through
a transcriptional repressor that senses acyl-chain length in membrane phospholipids.
Developmental Cell. 2014;29(6):P729-739. doi:10.1016/j.devcel.2014.04.025
apa: Hofbauer, H. F., Schopf, F. H., Schleifer, H., Knittelfelder, O. L., Pieber,
B., Rechberger, G. N., … Kohlwein, S. D. (2014). Regulation of gene expression
through a transcriptional repressor that senses acyl-chain length in membrane
phospholipids. Developmental Cell. Elsevier. https://doi.org/10.1016/j.devcel.2014.04.025
chicago: Hofbauer, Harald F., Florian H. Schopf, Hannes Schleifer, Oskar L. Knittelfelder,
Bartholomäus Pieber, Gerald N. Rechberger, Heimo Wolinski, et al. “Regulation
of Gene Expression through a Transcriptional Repressor That Senses Acyl-Chain
Length in Membrane Phospholipids.” Developmental Cell. Elsevier, 2014.
https://doi.org/10.1016/j.devcel.2014.04.025.
ieee: H. F. Hofbauer et al., “Regulation of gene expression through a transcriptional
repressor that senses acyl-chain length in membrane phospholipids,” Developmental
Cell, vol. 29, no. 6. Elsevier, pp. P729-739, 2014.
ista: Hofbauer HF, Schopf FH, Schleifer H, Knittelfelder OL, Pieber B, Rechberger
GN, Wolinski H, Gaspar ML, Kappe CO, Stadlmann J, Mechtler K, Zenz A, Lohner K,
Tehlivets O, Henry SA, Kohlwein SD. 2014. Regulation of gene expression through
a transcriptional repressor that senses acyl-chain length in membrane phospholipids.
Developmental Cell. 29(6), P729-739.
mla: Hofbauer, Harald F., et al. “Regulation of Gene Expression through a Transcriptional
Repressor That Senses Acyl-Chain Length in Membrane Phospholipids.” Developmental
Cell, vol. 29, no. 6, Elsevier, 2014, pp. P729-739, doi:10.1016/j.devcel.2014.04.025.
short: H.F. Hofbauer, F.H. Schopf, H. Schleifer, O.L. Knittelfelder, B. Pieber,
G.N. Rechberger, H. Wolinski, M.L. Gaspar, C.O. Kappe, J. Stadlmann, K. Mechtler,
A. Zenz, K. Lohner, O. Tehlivets, S.A. Henry, S.D. Kohlwein, Developmental Cell
29 (2014) P729-739.
date_created: 2022-08-25T08:42:42Z
date_published: 2014-06-23T00:00:00Z
date_updated: 2023-02-21T10:09:45Z
day: '23'
doi: 10.1016/j.devcel.2014.04.025
extern: '1'
external_id:
pmid:
- '24960695'
intvolume: ' 29'
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.devcel.2014.04.025
month: '06'
oa: 1
oa_version: Published Version
page: P729-739
pmid: 1
publication: Developmental Cell
publication_identifier:
eissn:
- 1878-1551
issn:
- 1534-5807
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Regulation of gene expression through a transcriptional repressor that senses
acyl-chain length in membrane phospholipids
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 29
year: '2014'
...
---
_id: '11987'
abstract:
- lang: eng
text: A method for the direct lithiation of terminal alkynes and heterocycles with
subsequent carboxylation in a continuous flow format was developed. This method
provides carboxylic acids at ambient conditions within less than five seconds
with only little excess of the organometallic base and CO2.
article_number: '13430'
article_processing_charge: No
article_type: letter_note
author:
- first_name: Bartholomäus
full_name: Pieber, Bartholomäus
id: 93e5e5b2-0da6-11ed-8a41-af589a024726
last_name: Pieber
orcid: 0000-0001-8689-388X
- first_name: Toma
full_name: Glasnov, Toma
last_name: Glasnov
- first_name: C. O.
full_name: Kappe, C. O.
last_name: Kappe
citation:
ama: 'Pieber B, Glasnov T, Kappe CO. Flash carboxylation: Fast lithiation–carboxylation
sequence at room temperature in continuous flow. RSC Advances. 2014;4(26).
doi:10.1039/c4ra01442a'
apa: 'Pieber, B., Glasnov, T., & Kappe, C. O. (2014). Flash carboxylation: Fast
lithiation–carboxylation sequence at room temperature in continuous flow. RSC
Advances. Royal Society of Chemistry. https://doi.org/10.1039/c4ra01442a'
chicago: 'Pieber, Bartholomäus, Toma Glasnov, and C. O. Kappe. “Flash Carboxylation:
Fast Lithiation–Carboxylation Sequence at Room Temperature in Continuous Flow.”
RSC Advances. Royal Society of Chemistry, 2014. https://doi.org/10.1039/c4ra01442a.'
ieee: 'B. Pieber, T. Glasnov, and C. O. Kappe, “Flash carboxylation: Fast lithiation–carboxylation
sequence at room temperature in continuous flow,” RSC Advances, vol. 4,
no. 26. Royal Society of Chemistry, 2014.'
ista: 'Pieber B, Glasnov T, Kappe CO. 2014. Flash carboxylation: Fast lithiation–carboxylation
sequence at room temperature in continuous flow. RSC Advances. 4(26), 13430.'
mla: 'Pieber, Bartholomäus, et al. “Flash Carboxylation: Fast Lithiation–Carboxylation
Sequence at Room Temperature in Continuous Flow.” RSC Advances, vol. 4,
no. 26, 13430, Royal Society of Chemistry, 2014, doi:10.1039/c4ra01442a.'
short: B. Pieber, T. Glasnov, C.O. Kappe, RSC Advances 4 (2014).
date_created: 2022-08-25T11:48:19Z
date_published: 2014-03-03T00:00:00Z
date_updated: 2023-02-21T10:10:31Z
day: '03'
doi: 10.1039/c4ra01442a
extern: '1'
intvolume: ' 4'
issue: '26'
language:
- iso: eng
month: '03'
oa_version: None
publication: RSC Advances
publication_identifier:
eissn:
- 2046-2069
publication_status: published
publisher: Royal Society of Chemistry
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Flash carboxylation: Fast lithiation–carboxylation sequence at room temperature
in continuous flow'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 4
year: '2014'
...
---
_id: '12633'
abstract:
- lang: eng
text: We use two hydrological models of varying complexity to study the Juncal River
Basin in the Central Andes of Chile with the aim to understand the degree of conceptualization
and the spatial structure that are needed to model present and future streamflows.
We use a conceptual semi-distributed model based on elevation bands [Water Evaluation
and Planning (WEAP)], frequently used for water management, and a physically oriented,
fully distributed model [Topographic Kinematic Wave Approximation and Integration
ETH Zurich (TOPKAPI-ETH)] developed for research purposes mainly. We evaluate
the ability of the two models to reproduce the key hydrological processes in the
basin with emphasis on snow accumulation and melt, streamflow and the relationships
between internal processes. Both models are capable of reproducing observed runoff
and the evolution of Moderate-resolution Imaging Spectroradiometer snow cover
adequately. In spite of WEAP's simple and conceptual approach for modelling snowmelt
and its lack of glacier representation and snow gravitational redistribution as
well as a proper routing algorithm, this model can reproduce historical data with
a similar goodness of fit as the more complex TOPKAPI-ETH. We show that the performance
of both models can be improved by using measured precipitation gradients of higher
temporal resolution. In contrast to the good performance of the conceptual model
for the present climate, however, we demonstrate that the simplifications in WEAP
lead to error compensation, which results in different predictions in simulated
melt and runoff for a potentially warmer future climate. TOPKAPI-ETH, using a
more physical representation of processes, depends less on calibration and thus
is less subject to a compensation of errors through different model components.
Our results show that data obtained locally in ad hoc short-term field campaigns
are needed to complement data extrapolated from long-term records for simulating
changes in the water cycle of high-elevation catchments but that these data can
only be efficiently used by a model applying a spatially distributed physical
representation of hydrological processes.
article_processing_charge: No
article_type: original
author:
- first_name: S.
full_name: Ragettli, S.
last_name: Ragettli
- first_name: G.
full_name: Cortés, G.
last_name: Cortés
- first_name: J.
full_name: McPhee, J.
last_name: McPhee
- first_name: Francesca
full_name: Pellicciotti, Francesca
id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
last_name: Pellicciotti
citation:
ama: Ragettli S, Cortés G, McPhee J, Pellicciotti F. An evaluation of approaches
for modelling hydrological processes in high-elevation, glacierized Andean watersheds.
Hydrological Processes. 2013;28(23):5674-5695. doi:10.1002/hyp.10055
apa: Ragettli, S., Cortés, G., McPhee, J., & Pellicciotti, F. (2013). An evaluation
of approaches for modelling hydrological processes in high-elevation, glacierized
Andean watersheds. Hydrological Processes. Wiley. https://doi.org/10.1002/hyp.10055
chicago: Ragettli, S., G. Cortés, J. McPhee, and Francesca Pellicciotti. “An Evaluation
of Approaches for Modelling Hydrological Processes in High-Elevation, Glacierized
Andean Watersheds.” Hydrological Processes. Wiley, 2013. https://doi.org/10.1002/hyp.10055.
ieee: S. Ragettli, G. Cortés, J. McPhee, and F. Pellicciotti, “An evaluation of
approaches for modelling hydrological processes in high-elevation, glacierized
Andean watersheds,” Hydrological Processes, vol. 28, no. 23. Wiley, pp.
5674–5695, 2013.
ista: Ragettli S, Cortés G, McPhee J, Pellicciotti F. 2013. An evaluation of approaches
for modelling hydrological processes in high-elevation, glacierized Andean watersheds.
Hydrological Processes. 28(23), 5674–5695.
mla: Ragettli, S., et al. “An Evaluation of Approaches for Modelling Hydrological
Processes in High-Elevation, Glacierized Andean Watersheds.” Hydrological Processes,
vol. 28, no. 23, Wiley, 2013, pp. 5674–95, doi:10.1002/hyp.10055.
short: S. Ragettli, G. Cortés, J. McPhee, F. Pellicciotti, Hydrological Processes
28 (2013) 5674–5695.
date_created: 2023-02-20T08:16:39Z
date_published: 2013-09-06T00:00:00Z
date_updated: 2023-02-24T08:48:40Z
day: '06'
doi: 10.1002/hyp.10055
extern: '1'
intvolume: ' 28'
issue: '23'
keyword:
- Water Science and Technology
language:
- iso: eng
month: '09'
oa_version: None
page: 5674-5695
publication: Hydrological Processes
publication_identifier:
issn:
- 0885-6087
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: An evaluation of approaches for modelling hydrological processes in high-elevation,
glacierized Andean watersheds
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 28
year: '2013'
...
---
_id: '12638'
abstract:
- lang: eng
text: Central Asian water resources largely depend on melt water generated in the
Pamir and Tien Shan mountain ranges. To estimate future water availability in
this region, it is necessary to use climate projections to estimate the future
glacier extent and volume. In this study, we evaluate the impact of uncertainty
in climate change projections on the future glacier extent in the Amu and Syr
Darya river basins. To this end we use the latest climate change projections generated
for the upcoming IPCC report (CMIP5) and, for comparison, projections used in
the fourth IPCC assessment (CMIP3). With these projections we force a regionalized
glacier mass balance model, and estimate changes in the basins' glacier extent
as a function of the glacier size distribution in the basins and projected temperature
and precipitation. This glacier mass balance model is specifically developed for
implementation in large scale hydrological models, where the spatial resolution
does not allow for simulating individual glaciers and data scarcity is an issue.
Although the CMIP5 ensemble results in greater regional warming than the CMIP3
ensemble and the range in projections for temperature as well as precipitation
is wider for the CMIP5 than for the CMIP3, the spread in projections of future
glacier extent in Central Asia is similar for both ensembles. This is because
differences in temperature rise are small during periods of maximum melt (July–September)
while differences in precipitation change are small during the period of maximum
accumulation (October–February). However, the model uncertainty due to parameter
uncertainty is high, and has roughly the same importance as uncertainty in the
climate projections. Uncertainty about the size of the decline in glacier extent
remains large, making estimates of future Central Asian glacier evolution and
downstream water availability uncertain.
article_processing_charge: No
article_type: original
author:
- first_name: A. F.
full_name: Lutz, A. F.
last_name: Lutz
- first_name: W. W.
full_name: Immerzeel, W. W.
last_name: Immerzeel
- first_name: A.
full_name: Gobiet, A.
last_name: Gobiet
- first_name: Francesca
full_name: Pellicciotti, Francesca
id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
last_name: Pellicciotti
- first_name: M. F. P.
full_name: Bierkens, M. F. P.
last_name: Bierkens
citation:
ama: Lutz AF, Immerzeel WW, Gobiet A, Pellicciotti F, Bierkens MFP. Comparison of
climate change signals in CMIP3 and CMIP5 multi-model ensembles and implications
for Central Asian glaciers. Hydrology and Earth System Sciences. 2013;17(9):3661-3677.
doi:10.5194/hess-17-3661-2013
apa: Lutz, A. F., Immerzeel, W. W., Gobiet, A., Pellicciotti, F., & Bierkens,
M. F. P. (2013). Comparison of climate change signals in CMIP3 and CMIP5 multi-model
ensembles and implications for Central Asian glaciers. Hydrology and Earth
System Sciences. Copernicus GmbH. https://doi.org/10.5194/hess-17-3661-2013
chicago: Lutz, A. F., W. W. Immerzeel, A. Gobiet, Francesca Pellicciotti, and M.
F. P. Bierkens. “Comparison of Climate Change Signals in CMIP3 and CMIP5 Multi-Model
Ensembles and Implications for Central Asian Glaciers.” Hydrology and Earth
System Sciences. Copernicus GmbH, 2013. https://doi.org/10.5194/hess-17-3661-2013.
ieee: A. F. Lutz, W. W. Immerzeel, A. Gobiet, F. Pellicciotti, and M. F. P. Bierkens,
“Comparison of climate change signals in CMIP3 and CMIP5 multi-model ensembles
and implications for Central Asian glaciers,” Hydrology and Earth System Sciences,
vol. 17, no. 9. Copernicus GmbH, pp. 3661–3677, 2013.
ista: Lutz AF, Immerzeel WW, Gobiet A, Pellicciotti F, Bierkens MFP. 2013. Comparison
of climate change signals in CMIP3 and CMIP5 multi-model ensembles and implications
for Central Asian glaciers. Hydrology and Earth System Sciences. 17(9), 3661–3677.
mla: Lutz, A. F., et al. “Comparison of Climate Change Signals in CMIP3 and CMIP5
Multi-Model Ensembles and Implications for Central Asian Glaciers.” Hydrology
and Earth System Sciences, vol. 17, no. 9, Copernicus GmbH, 2013, pp. 3661–77,
doi:10.5194/hess-17-3661-2013.
short: A.F. Lutz, W.W. Immerzeel, A. Gobiet, F. Pellicciotti, M.F.P. Bierkens, Hydrology
and Earth System Sciences 17 (2013) 3661–3677.
date_created: 2023-02-20T08:17:05Z
date_published: 2013-09-01T00:00:00Z
date_updated: 2023-02-24T08:19:48Z
day: '01'
doi: 10.5194/hess-17-3661-2013
extern: '1'
intvolume: ' 17'
issue: '9'
keyword:
- General Earth and Planetary Sciences
- General Engineering
- General Environmental Science
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.5194/hess-17-3661-2013
month: '09'
oa: 1
oa_version: Published Version
page: 3661-3677
publication: Hydrology and Earth System Sciences
publication_identifier:
issn:
- 1607-7938
publication_status: published
publisher: Copernicus GmbH
quality_controlled: '1'
scopus_import: '1'
status: public
title: Comparison of climate change signals in CMIP3 and CMIP5 multi-model ensembles
and implications for Central Asian glaciers
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 17
year: '2013'
...
---
_id: '12639'
abstract:
- lang: eng
text: 'In the headwater catchments of the main Asian rivers, glaciohydrological
models are a useful tool to anticipate impacts of climatic changes. However, the
reliability of their projections strongly depends on the quality and quantity
of data that are available for parameter estimation, model calibration and validation,
as well as on the accuracy of climate change projections. In this study the physically
oriented, glaciohydrological model TOPKAPI-ETH is used to simulate future changes
in snow, glacier, and runoff from the Hunza River Basin in northern Pakistan.
Three key sources of model uncertainty in future runoff projections are compared:
model parameters, climate projections, and natural climate variability. A novel
approach, applicable also to ungauged catchments, is used to determine which model
parameters and model components significantly affect the overall model uncertainty.
We show that the model is capable of reproducing streamflow and glacier mass balances,
but that all analyzed sources of uncertainty significantly affect the reliability
of future projections, and that their effect is variable in time and in space.
The effect of parametric uncertainty often exceeds the impact of climate uncertainty
and natural climate variability, especially in heavily glacierized subcatchments.
The results of the uncertainty analysis allow detailed recommendations on network
design and the timing and location of field measurements, which could efficiently
help to reduce model uncertainty in the future.'
article_processing_charge: No
article_type: original
author:
- first_name: S.
full_name: Ragettli, S.
last_name: Ragettli
- first_name: Francesca
full_name: Pellicciotti, Francesca
id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
last_name: Pellicciotti
- first_name: R.
full_name: Bordoy, R.
last_name: Bordoy
- first_name: W. W.
full_name: Immerzeel, W. W.
last_name: Immerzeel
citation:
ama: Ragettli S, Pellicciotti F, Bordoy R, Immerzeel WW. Sources of uncertainty
in modeling the glaciohydrological response of a Karakoram watershed to climate
change. Water Resources Research. 2013;49(9):6048-6066. doi:10.1002/wrcr.20450
apa: Ragettli, S., Pellicciotti, F., Bordoy, R., & Immerzeel, W. W. (2013).
Sources of uncertainty in modeling the glaciohydrological response of a Karakoram
watershed to climate change. Water Resources Research. American Geophysical
Union. https://doi.org/10.1002/wrcr.20450
chicago: Ragettli, S., Francesca Pellicciotti, R. Bordoy, and W. W. Immerzeel. “Sources
of Uncertainty in Modeling the Glaciohydrological Response of a Karakoram Watershed
to Climate Change.” Water Resources Research. American Geophysical Union,
2013. https://doi.org/10.1002/wrcr.20450.
ieee: S. Ragettli, F. Pellicciotti, R. Bordoy, and W. W. Immerzeel, “Sources of
uncertainty in modeling the glaciohydrological response of a Karakoram watershed
to climate change,” Water Resources Research, vol. 49, no. 9. American
Geophysical Union, pp. 6048–6066, 2013.
ista: Ragettli S, Pellicciotti F, Bordoy R, Immerzeel WW. 2013. Sources of uncertainty
in modeling the glaciohydrological response of a Karakoram watershed to climate
change. Water Resources Research. 49(9), 6048–6066.
mla: Ragettli, S., et al. “Sources of Uncertainty in Modeling the Glaciohydrological
Response of a Karakoram Watershed to Climate Change.” Water Resources Research,
vol. 49, no. 9, American Geophysical Union, 2013, pp. 6048–66, doi:10.1002/wrcr.20450.
short: S. Ragettli, F. Pellicciotti, R. Bordoy, W.W. Immerzeel, Water Resources
Research 49 (2013) 6048–6066.
date_created: 2023-02-20T08:17:12Z
date_published: 2013-03-01T00:00:00Z
date_updated: 2023-02-24T08:16:19Z
day: '01'
doi: 10.1002/wrcr.20450
extern: '1'
intvolume: ' 49'
issue: '9'
keyword:
- Water Science and Technology
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1002/wrcr.20450
month: '03'
oa: 1
oa_version: Published Version
page: 6048-6066
publication: Water Resources Research
publication_identifier:
issn:
- 0043-1397
publication_status: published
publisher: American Geophysical Union
quality_controlled: '1'
scopus_import: '1'
status: public
title: Sources of uncertainty in modeling the glaciohydrological response of a Karakoram
watershed to climate change
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 49
year: '2013'
...
---
_id: '12640'
abstract:
- lang: eng
text: Greater Himalayan glaciers are retreating and losing mass at rates comparable
to glaciers in other regions of the world1,2,3,4,5. Assessments of future changes
and their associated hydrological impacts are scarce, oversimplify glacier dynamics
or include a limited number of climate models6,7,8,9. Here, we use results from
the latest ensemble of climate models in combination with a high-resolution glacio-hydrological
model to assess the hydrological impact of climate change on two climatically
contrasting watersheds in the Greater Himalaya, the Baltoro and Langtang watersheds
that drain into the Indus and Ganges rivers, respectively. We show that the largest
uncertainty in future runoff is a result of variations in projected precipitation
between climate models. In both watersheds, strong, but highly variable, increases
in future runoff are projected and, despite the different characteristics of the
watersheds, their responses are surprisingly similar. In both cases, glaciers
will recede but net glacier melt runoff is on a rising limb at least until 2050.
In combination with a positive change in precipitation, water availability during
this century is not likely to decline. We conclude that river basins that depend
on monsoon rains and glacier melt will continue to sustain the increasing water
demands expected in these areas10.
article_processing_charge: No
article_type: letter_note
author:
- first_name: W. W.
full_name: Immerzeel, W. W.
last_name: Immerzeel
- first_name: Francesca
full_name: Pellicciotti, Francesca
id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
last_name: Pellicciotti
- first_name: M. F. P.
full_name: Bierkens, M. F. P.
last_name: Bierkens
citation:
ama: Immerzeel WW, Pellicciotti F, Bierkens MFP. Rising river flows throughout the
twenty-first century in two Himalayan glacierized watersheds. Nature Geoscience.
2013;6(9):742-745. doi:10.1038/ngeo1896
apa: Immerzeel, W. W., Pellicciotti, F., & Bierkens, M. F. P. (2013). Rising
river flows throughout the twenty-first century in two Himalayan glacierized watersheds.
Nature Geoscience. Springer Nature. https://doi.org/10.1038/ngeo1896
chicago: Immerzeel, W. W., Francesca Pellicciotti, and M. F. P. Bierkens. “Rising
River Flows throughout the Twenty-First Century in Two Himalayan Glacierized Watersheds.”
Nature Geoscience. Springer Nature, 2013. https://doi.org/10.1038/ngeo1896.
ieee: W. W. Immerzeel, F. Pellicciotti, and M. F. P. Bierkens, “Rising river flows
throughout the twenty-first century in two Himalayan glacierized watersheds,”
Nature Geoscience, vol. 6, no. 9. Springer Nature, pp. 742–745, 2013.
ista: Immerzeel WW, Pellicciotti F, Bierkens MFP. 2013. Rising river flows throughout
the twenty-first century in two Himalayan glacierized watersheds. Nature Geoscience.
6(9), 742–745.
mla: Immerzeel, W. W., et al. “Rising River Flows throughout the Twenty-First Century
in Two Himalayan Glacierized Watersheds.” Nature Geoscience, vol. 6, no.
9, Springer Nature, 2013, pp. 742–45, doi:10.1038/ngeo1896.
short: W.W. Immerzeel, F. Pellicciotti, M.F.P. Bierkens, Nature Geoscience 6 (2013)
742–745.
date_created: 2023-02-20T08:17:17Z
date_published: 2013-09-13T00:00:00Z
date_updated: 2023-02-21T10:46:37Z
day: '13'
doi: 10.1038/ngeo1896
extern: '1'
intvolume: ' 6'
issue: '9'
keyword:
- General Earth and Planetary Sciences
language:
- iso: eng
month: '09'
oa_version: None
page: 742-745
publication: Nature Geoscience
publication_identifier:
eissn:
- 1752-0908
issn:
- 1752-0894
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Rising river flows throughout the twenty-first century in two Himalayan glacierized
watersheds
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2013'
...
---
_id: '12641'
abstract:
- lang: eng
text: We investigate the sensitivity of a distributed enhanced temperature-index
(ETI) melt model, in order to understand which parameters have the largest influence
on model outputs and thus need to be accurately known. We use melt and meteorological
data from two Alpine glaciers and one glacier in the Andes of Chile. Sensitivity
analysis is conducted in a systematic way in terms of parameters and the different
conditions (day, night, clear-sky, overcast), melt seasons and glaciers examined.
The sensitivity of total melt to changes in individual parameters is calculated
using a local method around the optimal value of the parameters. We verify that
the parameters are optimal at the distributed scale and assess the model uncertainty
induced by uncertainty in the parameters using a Monte Carlo technique. Model
sensitivity to parameters is consistent across melt seasons, glaciers, different
conditions and the daily statistics examined. The parameters to which the model
is most sensitive are the shortwave-radiation factor, the temperature lapse rate
for extrapolation of air temperature, the albedo parameters, the temperature threshold
and the cloud transmittance factor parameters. A parameter uncertainty of 5% results
in a model uncertainty of 5.6% of mean melt on Haut Glacier d’Arolla, Switzerland.
article_processing_charge: No
article_type: original
author:
- first_name: Martin
full_name: Heynen, Martin
last_name: Heynen
- first_name: Francesca
full_name: Pellicciotti, Francesca
id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
last_name: Pellicciotti
- first_name: Marco
full_name: Carenzo, Marco
last_name: Carenzo
citation:
ama: Heynen M, Pellicciotti F, Carenzo M. Parameter sensitivity of a distributed
enhanced temperature-index melt model. Annals of Glaciology. 2013;54(63):311-321.
doi:10.3189/2013aog63a537
apa: Heynen, M., Pellicciotti, F., & Carenzo, M. (2013). Parameter sensitivity
of a distributed enhanced temperature-index melt model. Annals of Glaciology.
International Glaciological Society. https://doi.org/10.3189/2013aog63a537
chicago: Heynen, Martin, Francesca Pellicciotti, and Marco Carenzo. “Parameter Sensitivity
of a Distributed Enhanced Temperature-Index Melt Model.” Annals of Glaciology.
International Glaciological Society, 2013. https://doi.org/10.3189/2013aog63a537.
ieee: M. Heynen, F. Pellicciotti, and M. Carenzo, “Parameter sensitivity of a distributed
enhanced temperature-index melt model,” Annals of Glaciology, vol. 54,
no. 63. International Glaciological Society, pp. 311–321, 2013.
ista: Heynen M, Pellicciotti F, Carenzo M. 2013. Parameter sensitivity of a distributed
enhanced temperature-index melt model. Annals of Glaciology. 54(63), 311–321.
mla: Heynen, Martin, et al. “Parameter Sensitivity of a Distributed Enhanced Temperature-Index
Melt Model.” Annals of Glaciology, vol. 54, no. 63, International Glaciological
Society, 2013, pp. 311–21, doi:10.3189/2013aog63a537.
short: M. Heynen, F. Pellicciotti, M. Carenzo, Annals of Glaciology 54 (2013) 311–321.
date_created: 2023-02-20T08:17:21Z
date_published: 2013-08-01T00:00:00Z
date_updated: 2023-02-21T10:43:42Z
day: '01'
doi: 10.3189/2013aog63a537
extern: '1'
intvolume: ' 54'
issue: '63'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.3189/2013aog63a537
month: '08'
oa: 1
oa_version: Published Version
page: 311-321
publication: Annals of Glaciology
publication_identifier:
eissn:
- 1727-5644
issn:
- 0260-3055
publication_status: published
publisher: International Glaciological Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Parameter sensitivity of a distributed enhanced temperature-index melt model
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 54
year: '2013'
...
---
_id: '12642'
abstract:
- lang: eng
text: Near-surface air temperature, typically measured at a height of 2 m, is the
most important control on the energy exchange and the melt rate at a snow or ice
surface. It is distributed in a simplistic manner in most glacier melt models
by using constant linear lapse rates, which poorly represent the actual spatial
and temporal variability of air temperature. In this paper, we test a simple thermodynamic
model proposed by Greuell and Böhm in 1998 as an alternative, using a new dataset
of air temperature measurements from along the flowline of Haut Glacier d’Arolla,
Switzerland. The unmodified model performs little better than assuming a constant
linear lapse rate. When modified to allow the ratio of the boundary layer height
to the bulk heat transfer coefficient to vary along the flowline, the model matches
measured air temperatures better, and a further reduction of the root-mean-square
error is obtained, although there is still considerable scope for improvement.
The modified model is shown to perform best under conditions favourable to the
development of katabatic winds – few clouds, positive ambient air temperature,
limited influence of synoptic or valley winds and a long fetch – but its performance
is poor under cloudy conditions.
article_processing_charge: No
article_type: original
author:
- first_name: Lene
full_name: Petersen, Lene
last_name: Petersen
- first_name: Francesca
full_name: Pellicciotti, Francesca
id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
last_name: Pellicciotti
- first_name: Inge
full_name: Juszak, Inge
last_name: Juszak
- first_name: Marco
full_name: Carenzo, Marco
last_name: Carenzo
- first_name: Ben
full_name: Brock, Ben
last_name: Brock
citation:
ama: 'Petersen L, Pellicciotti F, Juszak I, Carenzo M, Brock B. Suitability of a
constant air temperature lapse rate over an Alpine glacier: Testing the Greuell
and Böhm model as an alternative. Annals of Glaciology. 2013;54(63):120-130.
doi:10.3189/2013aog63a477'
apa: 'Petersen, L., Pellicciotti, F., Juszak, I., Carenzo, M., & Brock, B. (2013).
Suitability of a constant air temperature lapse rate over an Alpine glacier: Testing
the Greuell and Böhm model as an alternative. Annals of Glaciology. International
Glaciological Society. https://doi.org/10.3189/2013aog63a477'
chicago: 'Petersen, Lene, Francesca Pellicciotti, Inge Juszak, Marco Carenzo, and
Ben Brock. “Suitability of a Constant Air Temperature Lapse Rate over an Alpine
Glacier: Testing the Greuell and Böhm Model as an Alternative.” Annals of Glaciology.
International Glaciological Society, 2013. https://doi.org/10.3189/2013aog63a477.'
ieee: 'L. Petersen, F. Pellicciotti, I. Juszak, M. Carenzo, and B. Brock, “Suitability
of a constant air temperature lapse rate over an Alpine glacier: Testing the Greuell
and Böhm model as an alternative,” Annals of Glaciology, vol. 54, no. 63.
International Glaciological Society, pp. 120–130, 2013.'
ista: 'Petersen L, Pellicciotti F, Juszak I, Carenzo M, Brock B. 2013. Suitability
of a constant air temperature lapse rate over an Alpine glacier: Testing the Greuell
and Böhm model as an alternative. Annals of Glaciology. 54(63), 120–130.'
mla: 'Petersen, Lene, et al. “Suitability of a Constant Air Temperature Lapse Rate
over an Alpine Glacier: Testing the Greuell and Böhm Model as an Alternative.”
Annals of Glaciology, vol. 54, no. 63, International Glaciological Society,
2013, pp. 120–30, doi:10.3189/2013aog63a477.'
short: L. Petersen, F. Pellicciotti, I. Juszak, M. Carenzo, B. Brock, Annals of
Glaciology 54 (2013) 120–130.
date_created: 2023-02-20T08:17:29Z
date_published: 2013-08-01T00:00:00Z
date_updated: 2023-02-21T10:18:24Z
day: '01'
doi: 10.3189/2013aog63a477
extern: '1'
intvolume: ' 54'
issue: '63'
keyword:
- Earth-Surface Processes
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.3189/2013aog63a477
month: '08'
oa: 1
oa_version: Published Version
page: 120-130
publication: Annals of Glaciology
publication_identifier:
eissn:
- 1727-5644
issn:
- 0260-3055
publication_status: published
publisher: International Glaciological Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Suitability of a constant air temperature lapse rate over an Alpine glacier:
Testing the Greuell and Böhm model as an alternative'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 54
year: '2013'
...
---
_id: '12643'
abstract:
- lang: eng
text: Parameterizations of incoming longwave radiation are increasingly receiving
attention for both low and high elevation glacierized sites. In this paper, we
test 13 clear-sky parameterizations combined with seven cloud corrections for
all-sky atmospheric emissivity at one location on Haut Glacier d'Arolla. We also
analyze the four seasons separately and conduct a cross-validation to test the
parameters’ robustness. The best parameterization is the one by Dilley and O'Brien,
B for clear-sky conditions combined with Unsworth and Monteith cloud correction.
This model is also the most robust when tested in cross-validation. When validated
at different sites in the southern Alps of Switzerland and north-western Italian
Alps, all parameterizations show a substantial decrease in performance, except
for one site, thus suggesting that it is important to recalibrate parameterizations
of incoming longwave radiation for different locations. We argue that this is
due to differences in the structure of the atmosphere at the sites. We also quantify
the effect that the incoming longwave radiation parameterizations have on energy-balance
melt modeling, and show that recalibration of model parameters is needed. Using
parameters from other sites leads to a significant underestimation of melt and
to an error that is larger than that associated with using different parameterizations.
Once recalibrated, however, the parameters of most models seem to be stable over
seasons and years at the location on Haut Glacier d'Arolla.
article_processing_charge: No
article_type: original
author:
- first_name: I.
full_name: Juszak, I.
last_name: Juszak
- first_name: Francesca
full_name: Pellicciotti, Francesca
id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
last_name: Pellicciotti
citation:
ama: 'Juszak I, Pellicciotti F. A comparison of parameterizations of incoming longwave
radiation over melting glaciers: Model robustness and seasonal variability. Journal
of Geophysical Research: Atmospheres. 2013;118(8):3066-3084. doi:10.1002/jgrd.50277'
apa: 'Juszak, I., & Pellicciotti, F. (2013). A comparison of parameterizations
of incoming longwave radiation over melting glaciers: Model robustness and seasonal
variability. Journal of Geophysical Research: Atmospheres. American Geophysical
Union. https://doi.org/10.1002/jgrd.50277'
chicago: 'Juszak, I., and Francesca Pellicciotti. “A Comparison of Parameterizations
of Incoming Longwave Radiation over Melting Glaciers: Model Robustness and Seasonal
Variability.” Journal of Geophysical Research: Atmospheres. American Geophysical
Union, 2013. https://doi.org/10.1002/jgrd.50277.'
ieee: 'I. Juszak and F. Pellicciotti, “A comparison of parameterizations of incoming
longwave radiation over melting glaciers: Model robustness and seasonal variability,”
Journal of Geophysical Research: Atmospheres, vol. 118, no. 8. American
Geophysical Union, pp. 3066–3084, 2013.'
ista: 'Juszak I, Pellicciotti F. 2013. A comparison of parameterizations of incoming
longwave radiation over melting glaciers: Model robustness and seasonal variability.
Journal of Geophysical Research: Atmospheres. 118(8), 3066–3084.'
mla: 'Juszak, I., and Francesca Pellicciotti. “A Comparison of Parameterizations
of Incoming Longwave Radiation over Melting Glaciers: Model Robustness and Seasonal
Variability.” Journal of Geophysical Research: Atmospheres, vol. 118, no.
8, American Geophysical Union, 2013, pp. 3066–84, doi:10.1002/jgrd.50277.'
short: 'I. Juszak, F. Pellicciotti, Journal of Geophysical Research: Atmospheres
118 (2013) 3066–3084.'
date_created: 2023-02-20T08:17:34Z
date_published: 2013-04-27T00:00:00Z
date_updated: 2023-02-21T10:10:46Z
day: '27'
doi: 10.1002/jgrd.50277
extern: '1'
intvolume: ' 118'
issue: '8'
keyword:
- Space and Planetary Science
- Earth and Planetary Sciences (miscellaneous)
- Atmospheric Science
- Geophysics
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1002/jgrd.50277
month: '04'
oa: 1
oa_version: Published Version
page: 3066-3084
publication: 'Journal of Geophysical Research: Atmospheres'
publication_identifier:
issn:
- 2169-897X
publication_status: published
publisher: American Geophysical Union
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'A comparison of parameterizations of incoming longwave radiation over melting
glaciers: Model robustness and seasonal variability'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 118
year: '2013'
...
---
_id: '1304'
abstract:
- lang: eng
text: When confronted with a large-field stimulus rotating around the vertical body
axis, flies display a following behavior called "optomotor response."
As neural control elements, the large tangential horizontal system (HS) cells
of the lobula plate have been prime candidates for long. Here, we applied optogenetic
stimulation of HS cells to evaluate their behavioral role in Drosophila. To minimize
interference of the optical activation of channelrhodopsin-2 with the visual perception
of the flies, we used a bistable variant called ChR2-C128S. By applying pulses
of blue and yellow light, we first demonstrate electrophysiologically that lobula
plate tangential cells can be activated and deactivated repeatedly with no evident
change in depolarization strength over trials. We next show that selective optogenetic
activation of HS cells elicits robust yaw head movements and yaw turning responses
in fixed and tethered flying flies, respectively.
acknowledgement: 'This work was supported by the Max Planck Society. '
author:
- first_name: Väinö
full_name: Haikala, Väinö
last_name: Haikala
- first_name: Maximilian A
full_name: Maximilian Jösch
id: 2BD278E6-F248-11E8-B48F-1D18A9856A87
last_name: Jösch
orcid: 0000-0002-3937-1330
- first_name: Alexander
full_name: Borst, Alexander
last_name: Borst
- first_name: Alex
full_name: Mauss, Alex S
last_name: Mauss
citation:
ama: Haikala V, Jösch MA, Borst A, Mauss A. Optogenetic control of fly optomotor
responses. Journal of Neuroscience. 2013;33(34):13927-13934. doi:10.1523/JNEUROSCI.0340-13.2013
apa: Haikala, V., Jösch, M. A., Borst, A., & Mauss, A. (2013). Optogenetic control
of fly optomotor responses. Journal of Neuroscience. Society for Neuroscience.
https://doi.org/10.1523/JNEUROSCI.0340-13.2013
chicago: Haikala, Väinö, Maximilian A Jösch, Alexander Borst, and Alex Mauss. “Optogenetic
Control of Fly Optomotor Responses.” Journal of Neuroscience. Society for
Neuroscience, 2013. https://doi.org/10.1523/JNEUROSCI.0340-13.2013.
ieee: V. Haikala, M. A. Jösch, A. Borst, and A. Mauss, “Optogenetic control of fly
optomotor responses,” Journal of Neuroscience, vol. 33, no. 34. Society
for Neuroscience, pp. 13927–13934, 2013.
ista: Haikala V, Jösch MA, Borst A, Mauss A. 2013. Optogenetic control of fly optomotor
responses. Journal of Neuroscience. 33(34), 13927–13934.
mla: Haikala, Väinö, et al. “Optogenetic Control of Fly Optomotor Responses.” Journal
of Neuroscience, vol. 33, no. 34, Society for Neuroscience, 2013, pp. 13927–34,
doi:10.1523/JNEUROSCI.0340-13.2013.
short: V. Haikala, M.A. Jösch, A. Borst, A. Mauss, Journal of Neuroscience 33 (2013)
13927–13934.
date_created: 2018-12-11T11:51:16Z
date_published: 2013-01-01T00:00:00Z
date_updated: 2021-01-12T06:49:45Z
day: '01'
doi: 10.1523/JNEUROSCI.0340-13.2013
extern: 1
intvolume: ' 33'
issue: '34'
month: '01'
page: 13927 - 13934
publication: Journal of Neuroscience
publication_status: published
publisher: Society for Neuroscience
publist_id: '5967'
quality_controlled: 0
status: public
title: Optogenetic control of fly optomotor responses
type: journal_article
volume: 33
year: '2013'
...
---
_id: '1305'
abstract:
- lang: eng
text: In the fly Drosophila melanogaster, photoreceptor input to motion vision is
split into two parallel pathways as represented by first-order interneurons L1
and L2 (Rister et al., 2007; Joesch et al., 2010). However, how these pathways
are functionally specialized remains controversial. One study (Eichner et al.,
2011) proposed that the L1-pathway evaluates only sequences of brightness increments
(ON-ON), while the L2-pathway processes exclusively brightness decrements (OFF-OFF).
Another study (Clark et al., 2011) proposed that each of the two pathways evaluates
both ON-ON and OFF-OFF sequences. To decide between these alternatives, we recorded
from motionsensitive neurons in flies in which the output from either L1 or L2
was genetically blocked. We found that blocking L1 abolishes ON-ON responses but
leaves OFF-OFF responses intact. The opposite was true, when the output from L2
was blocked. We conclude that the L1 and L2 pathways are functionally specialized
to detect ON-ON and OFF-OFF sequences, respectively.
acknowledgement: This work was supported by the Max-Planck-Society and the SFB 870
of the Deutsche Forschungsgemeinschaft.
author:
- first_name: Maximilian A
full_name: Maximilian Jösch
id: 2BD278E6-F248-11E8-B48F-1D18A9856A87
last_name: Jösch
orcid: 0000-0002-3937-1330
- first_name: Franz
full_name: Weber, Franz
last_name: Weber
- first_name: Hubert
full_name: Eichner, Hubert
last_name: Eichner
- first_name: Alexander
full_name: Borst, Alexander
last_name: Borst
citation:
ama: Jösch MA, Weber F, Eichner H, Borst A. Functional specialization of parallel
motion detection circuits in the fly. Journal of Neuroscience. 2013;33(3):902-905.
doi:10.1523/JNEUROSCI.3374-12.2013
apa: Jösch, M. A., Weber, F., Eichner, H., & Borst, A. (2013). Functional specialization
of parallel motion detection circuits in the fly. Journal of Neuroscience.
Society for Neuroscience. https://doi.org/10.1523/JNEUROSCI.3374-12.2013
chicago: Jösch, Maximilian A, Franz Weber, Hubert Eichner, and Alexander Borst.
“Functional Specialization of Parallel Motion Detection Circuits in the Fly.”
Journal of Neuroscience. Society for Neuroscience, 2013. https://doi.org/10.1523/JNEUROSCI.3374-12.2013.
ieee: M. A. Jösch, F. Weber, H. Eichner, and A. Borst, “Functional specialization
of parallel motion detection circuits in the fly,” Journal of Neuroscience,
vol. 33, no. 3. Society for Neuroscience, pp. 902–905, 2013.
ista: Jösch MA, Weber F, Eichner H, Borst A. 2013. Functional specialization of
parallel motion detection circuits in the fly. Journal of Neuroscience. 33(3),
902–905.
mla: Jösch, Maximilian A., et al. “Functional Specialization of Parallel Motion
Detection Circuits in the Fly.” Journal of Neuroscience, vol. 33, no. 3,
Society for Neuroscience, 2013, pp. 902–05, doi:10.1523/JNEUROSCI.3374-12.2013.
short: M.A. Jösch, F. Weber, H. Eichner, A. Borst, Journal of Neuroscience 33 (2013)
902–905.
date_created: 2018-12-11T11:51:16Z
date_published: 2013-01-16T00:00:00Z
date_updated: 2021-01-12T06:49:45Z
day: '16'
doi: 10.1523/JNEUROSCI.3374-12.2013
extern: 1
intvolume: ' 33'
issue: '3'
month: '01'
page: 902 - 905
publication: Journal of Neuroscience
publication_status: published
publisher: Society for Neuroscience
publist_id: '5968'
quality_controlled: 0
status: public
title: Functional specialization of parallel motion detection circuits in the fly
type: journal_article
volume: 33
year: '2013'
...
---
_id: '1307'
abstract:
- lang: eng
text: We prove uniqueness of solutions of the DLSS equation in a class of sufficiently
regular functions. The global weak solutions of the DLSS equation constructed
by Jüngel and Matthes belong to this class of uniqueness. We also show uniqueness
of solutions for the quantum drift-diffusion equation, which contains additional
drift and second-order diffusion terms. The results hold in case of periodic or
Dirichlet-Neumann boundary conditions. Our proof is based on a monotonicity property
of the DLSS operator and sophisticated approximation arguments; we derive a PDE
satisfied by the pointwise square root of the solution, which enables us to exploit
the monotonicity property of the operator.
author:
- first_name: Julian L
full_name: Julian Fischer
id: 2C12A0B0-F248-11E8-B48F-1D18A9856A87
last_name: Fischer
orcid: 0000-0002-0479-558X
citation:
ama: Fischer JL. Uniqueness of solutions of the Derrida-Lebowitz-Speer-Spohn equation
and quantum drift diffusion models. Communications in Partial Differential
Equations. 2013;38(11):2004-2047. doi:10.1080/03605302.2013.823548
apa: Fischer, J. L. (2013). Uniqueness of solutions of the Derrida-Lebowitz-Speer-Spohn
equation and quantum drift diffusion models. Communications in Partial Differential
Equations. Taylor & Francis. https://doi.org/10.1080/03605302.2013.823548
chicago: Fischer, Julian L. “Uniqueness of Solutions of the Derrida-Lebowitz-Speer-Spohn
Equation and Quantum Drift Diffusion Models.” Communications in Partial Differential
Equations. Taylor & Francis, 2013. https://doi.org/10.1080/03605302.2013.823548.
ieee: J. L. Fischer, “Uniqueness of solutions of the Derrida-Lebowitz-Speer-Spohn
equation and quantum drift diffusion models,” Communications in Partial Differential
Equations, vol. 38, no. 11. Taylor & Francis, pp. 2004–2047, 2013.
ista: Fischer JL. 2013. Uniqueness of solutions of the Derrida-Lebowitz-Speer-Spohn
equation and quantum drift diffusion models. Communications in Partial Differential
Equations. 38(11), 2004–2047.
mla: Fischer, Julian L. “Uniqueness of Solutions of the Derrida-Lebowitz-Speer-Spohn
Equation and Quantum Drift Diffusion Models.” Communications in Partial Differential
Equations, vol. 38, no. 11, Taylor & Francis, 2013, pp. 2004–47, doi:10.1080/03605302.2013.823548.
short: J.L. Fischer, Communications in Partial Differential Equations 38 (2013)
2004–2047.
date_created: 2018-12-11T11:51:17Z
date_published: 2013-11-01T00:00:00Z
date_updated: 2021-01-12T06:49:46Z
day: '01'
doi: 10.1080/03605302.2013.823548
extern: 1
intvolume: ' 38'
issue: '11'
month: '11'
page: 2004 - 2047
publication: Communications in Partial Differential Equations
publication_status: published
publisher: Taylor & Francis
publist_id: '5962'
quality_controlled: 0
status: public
title: Uniqueness of solutions of the Derrida-Lebowitz-Speer-Spohn equation and quantum
drift diffusion models
type: journal_article
volume: 38
year: '2013'
...
---
_id: '1308'
abstract:
- lang: eng
text: We derive sufficient conditions for advection-driven backward motion of the
free boundary in a chemotaxis model with degenerate mobility. In this model, a
porous-medium-type diffusive term and an advection term are in competition. The
former induces forward motion, the latter may induce backward motion of the free
boundary depending on the direction of advection. We deduce conditions on the
growth of the initial data at the free boundary which ensure that at least initially
the advection term is dominant. This implies local backward motion of the free
boundary provided the advection is (locally) directed appropriately. Our result
is based on a new class of moving test functions and Stampacchia's lemma. As a
by-product of our estimates, we obtain quantitative bounds on the spreading of
the support of solutions for the chemotaxis model and provide a proof for the
finite speed of the support propagation property of solutions.
author:
- first_name: Julian L
full_name: Julian Fischer
id: 2C12A0B0-F248-11E8-B48F-1D18A9856A87
last_name: Fischer
orcid: 0000-0002-0479-558X
citation:
ama: Fischer JL. Advection-driven support shrinking in a chemotaxis model with degenerate
mobility. SIAM Journal on Mathematical Analysis. 2013;45(3):1585-1615.
doi:10.1137/120874291
apa: Fischer, J. L. (2013). Advection-driven support shrinking in a chemotaxis model
with degenerate mobility. SIAM Journal on Mathematical Analysis. Society
for Industrial and Applied Mathematics . https://doi.org/10.1137/120874291
chicago: Fischer, Julian L. “Advection-Driven Support Shrinking in a Chemotaxis
Model with Degenerate Mobility.” SIAM Journal on Mathematical Analysis.
Society for Industrial and Applied Mathematics , 2013. https://doi.org/10.1137/120874291.
ieee: J. L. Fischer, “Advection-driven support shrinking in a chemotaxis model with
degenerate mobility,” SIAM Journal on Mathematical Analysis, vol. 45, no.
3. Society for Industrial and Applied Mathematics , pp. 1585–1615, 2013.
ista: Fischer JL. 2013. Advection-driven support shrinking in a chemotaxis model
with degenerate mobility. SIAM Journal on Mathematical Analysis. 45(3), 1585–1615.
mla: Fischer, Julian L. “Advection-Driven Support Shrinking in a Chemotaxis Model
with Degenerate Mobility.” SIAM Journal on Mathematical Analysis, vol.
45, no. 3, Society for Industrial and Applied Mathematics , 2013, pp. 1585–615,
doi:10.1137/120874291.
short: J.L. Fischer, SIAM Journal on Mathematical Analysis 45 (2013) 1585–1615.
date_created: 2018-12-11T11:51:17Z
date_published: 2013-01-01T00:00:00Z
date_updated: 2021-01-12T06:49:46Z
day: '01'
doi: 10.1137/120874291
extern: 1
intvolume: ' 45'
issue: '3'
month: '01'
page: 1585 - 1615
publication: SIAM Journal on Mathematical Analysis
publication_status: published
publisher: 'Society for Industrial and Applied Mathematics '
publist_id: '5963'
quality_controlled: 0
status: public
title: Advection-driven support shrinking in a chemotaxis model with degenerate mobility
type: journal_article
volume: 45
year: '2013'
...
---
_id: '1310'
abstract:
- lang: eng
text: We derive lower bounds on asymptotic support propagation rates for strong
solutions of the Cauchy problem for the thin-film equation. The bounds coincide
up to a constant factor with the previously known upper bounds and thus are sharp.
Our results hold in case of at most three spatial dimensions and n∈. (1, 2.92).
The result is established using weighted backward entropy inequalities with singular
weight functions to yield a differential inequality; combined with some entropy
production estimates, the optimal rate of propagation is obtained. To the best
of our knowledge, these are the first lower bounds on asymptotic support propagation
rates for higher-order nonnegativity-preserving parabolic equations.
author:
- first_name: Julian L
full_name: Julian Fischer
id: 2C12A0B0-F248-11E8-B48F-1D18A9856A87
last_name: Fischer
orcid: 0000-0002-0479-558X
citation:
ama: Fischer JL. Optimal lower bounds on asymptotic support propagation rates for
the thin-film equation. Journal of Differential Equations. 2013;255(10):3127-3149.
doi:10.1016/j.jde.2013.07.028
apa: Fischer, J. L. (2013). Optimal lower bounds on asymptotic support propagation
rates for the thin-film equation. Journal of Differential Equations. Academic
Press. https://doi.org/10.1016/j.jde.2013.07.028
chicago: Fischer, Julian L. “Optimal Lower Bounds on Asymptotic Support Propagation
Rates for the Thin-Film Equation.” Journal of Differential Equations. Academic
Press, 2013. https://doi.org/10.1016/j.jde.2013.07.028.
ieee: J. L. Fischer, “Optimal lower bounds on asymptotic support propagation rates
for the thin-film equation,” Journal of Differential Equations, vol. 255,
no. 10. Academic Press, pp. 3127–3149, 2013.
ista: Fischer JL. 2013. Optimal lower bounds on asymptotic support propagation rates
for the thin-film equation. Journal of Differential Equations. 255(10), 3127–3149.
mla: Fischer, Julian L. “Optimal Lower Bounds on Asymptotic Support Propagation
Rates for the Thin-Film Equation.” Journal of Differential Equations, vol.
255, no. 10, Academic Press, 2013, pp. 3127–49, doi:10.1016/j.jde.2013.07.028.
short: J.L. Fischer, Journal of Differential Equations 255 (2013) 3127–3149.
date_created: 2018-12-11T11:51:18Z
date_published: 2013-11-15T00:00:00Z
date_updated: 2021-01-12T06:49:47Z
day: '15'
doi: 10.1016/j.jde.2013.07.028
extern: 1
intvolume: ' 255'
issue: '10'
month: '11'
page: 3127 - 3149
publication: Journal of Differential Equations
publication_status: published
publisher: Academic Press
publist_id: '5961'
quality_controlled: 0
status: public
title: Optimal lower bounds on asymptotic support propagation rates for the thin-film
equation
type: journal_article
volume: 255
year: '2013'
...
---
_id: '8245'
abstract:
- lang: eng
text: "Background: Monoclonal antibodies (mAb), such as trastuzumab are a valuable
addition to breast cancer therapy.\r\nData obtained from neoadjuvant settings
revealed that antibody-dependent cell-mediated cytotoxicity (ADCC) is a\r\nmajor
mechanism of action for the mAb trastuzumab. Conflicting results still call into
question whether disease\r\nprogression, prolonged treatment or concomitant chemotherapy
influences ADCC and related immunological\r\nphenomena.\r\nMethods: We analyzed
the activity of ADCC and antibody-dependent cell-mediated phagocytosis (ADCP)
of\r\nperipheral blood mononuclear cells (PBMCs) from human epidermal growth factor
receptor 2 (HER2/neu) positive\r\nbreast cancer patients receiving trastuzumab
therapy either in an adjuvant (n = 13) or metastatic (n = 15) setting as\r\nwell
as from trastuzumab treatment-naive (t-naive) HER2/neu negative patients (n =
15). PBMCs from healthy volunteers\r\n(n = 24) were used as controls. ADCC and
ADCP activity was correlated with the expression of antibody binding\r\nFc-gamma
receptor (FcγR)I (CD64), FcγRII (CD32) and FcγRIII (CD16) on CD14+ (monocytes)
and CD56+ (NK) cells, as well as the expression of CD107a+ (LAMP-1) on CD56+ cells
and the total amount of CD4+CD25+FOXP3+ (Treg) cells. In metastatic patients,
markers were correlated with progression-free survival (PFS).\r\nResults: ADCC
activity was significantly down regulated in metastatic, adjuvant and t-naive
patient cohorts as compared to healthy controls. Reduced ADCC activity was inversely
correlated with the expression of CD107a on CD56+\r\ncells in adjuvant patients.
ADCC and ADCP activity of the patient cohorts were similar, regardless of treatment
duration\r\nor additional chemotherapy. PFS in metastatic patients inversely correlated
with the number of peripheral Treg cells.\r\nConclusion: The reduction of ADCC
in patients as compared to healthy controls calls for adjuvant strategies, such
as\r\nimmune-enhancing agents, to improve the activity of trastuzumab. However,
efficacy of trastuzumab-specific ADCC\r\nand ADCP appears not to be affected by
treatment duration, disease progression or concomitant chemotherapy. This\r\nfinding
supports the application of trastuzumab at any stage of the disease."
article_number: '307'
article_processing_charge: No
author:
- first_name: Branka
full_name: Petricevic, Branka
last_name: Petricevic
- first_name: Johannes
full_name: Laengle, Johannes
last_name: Laengle
- first_name: Josef
full_name: Singer, Josef
last_name: Singer
- first_name: Monika
full_name: Sachet, Monika
last_name: Sachet
- first_name: Judit
full_name: Fazekas, Judit
id: 36432834-F248-11E8-B48F-1D18A9856A87
last_name: Fazekas
orcid: 0000-0002-8777-3502
- first_name: Guenther
full_name: Steger, Guenther
last_name: Steger
- first_name: Rupert
full_name: Bartsch, Rupert
last_name: Bartsch
- first_name: Erika
full_name: Jensen-Jarolim, Erika
last_name: Jensen-Jarolim
- first_name: Michael
full_name: Bergmann, Michael
last_name: Bergmann
citation:
ama: Petricevic B, Laengle J, Singer J, et al. Trastuzumab mediates antibody-dependent
cell-mediated cytotoxicity and phagocytosis to the same extent in both adjuvant
and metastatic HER2/neu breast cancer patients. Journal of Translational Medicine.
2013;11. doi:10.1186/1479-5876-11-307
apa: Petricevic, B., Laengle, J., Singer, J., Sachet, M., Singer, J., Steger, G.,
… Bergmann, M. (2013). Trastuzumab mediates antibody-dependent cell-mediated cytotoxicity
and phagocytosis to the same extent in both adjuvant and metastatic HER2/neu breast
cancer patients. Journal of Translational Medicine. Springer Nature. https://doi.org/10.1186/1479-5876-11-307
chicago: Petricevic, Branka, Johannes Laengle, Josef Singer, Monika Sachet, Judit
Singer, Guenther Steger, Rupert Bartsch, Erika Jensen-Jarolim, and Michael Bergmann.
“Trastuzumab Mediates Antibody-Dependent Cell-Mediated Cytotoxicity and Phagocytosis
to the Same Extent in Both Adjuvant and Metastatic HER2/Neu Breast Cancer Patients.”
Journal of Translational Medicine. Springer Nature, 2013. https://doi.org/10.1186/1479-5876-11-307.
ieee: B. Petricevic et al., “Trastuzumab mediates antibody-dependent cell-mediated
cytotoxicity and phagocytosis to the same extent in both adjuvant and metastatic
HER2/neu breast cancer patients,” Journal of Translational Medicine, vol.
11. Springer Nature, 2013.
ista: Petricevic B, Laengle J, Singer J, Sachet M, Singer J, Steger G, Bartsch R,
Jensen-Jarolim E, Bergmann M. 2013. Trastuzumab mediates antibody-dependent cell-mediated
cytotoxicity and phagocytosis to the same extent in both adjuvant and metastatic
HER2/neu breast cancer patients. Journal of Translational Medicine. 11, 307.
mla: Petricevic, Branka, et al. “Trastuzumab Mediates Antibody-Dependent Cell-Mediated
Cytotoxicity and Phagocytosis to the Same Extent in Both Adjuvant and Metastatic
HER2/Neu Breast Cancer Patients.” Journal of Translational Medicine, vol.
11, 307, Springer Nature, 2013, doi:10.1186/1479-5876-11-307.
short: B. Petricevic, J. Laengle, J. Singer, M. Sachet, J. Singer, G. Steger, R.
Bartsch, E. Jensen-Jarolim, M. Bergmann, Journal of Translational Medicine 11
(2013).
date_created: 2020-08-10T11:54:34Z
date_published: 2013-12-12T00:00:00Z
date_updated: 2022-08-25T14:52:39Z
day: '12'
ddc:
- '570'
doi: 10.1186/1479-5876-11-307
extern: '1'
external_id:
pmid:
- '24330813'
file:
- access_level: open_access
content_type: application/pdf
creator: dernst
date_created: 2020-08-10T13:45:19Z
date_updated: 2020-08-10T13:45:19Z
file_id: '8247'
file_name: 2013_JoTM_Petricevic.pdf
file_size: 777311
relation: main_file
success: 1
file_date_updated: 2020-08-10T13:45:19Z
has_accepted_license: '1'
intvolume: ' 11'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/3.0/
month: '12'
oa: 1
oa_version: None
pmid: 1
publication: Journal of Translational Medicine
publication_identifier:
issn:
- 1479-5876
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Trastuzumab mediates antibody-dependent cell-mediated cytotoxicity and phagocytosis
to the same extent in both adjuvant and metastatic HER2/neu breast cancer patients
tmp:
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legal_code_url: https://creativecommons.org/licenses/by/3.0/legalcode
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type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
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