---
_id: '1241'
abstract:
- lang: eng
  text: 'How likely is it that a population escapes extinction through adaptive evolution?
    The answer to this question is of great relevance in conservation biology, where
    we aim at species’ rescue and the maintenance of biodiversity, and in agriculture
    and medicine, where we seek to hamper the emergence of pesticide or drug resistance.
    By reshuffling the genome, recombination has two antagonistic effects on the probability
    of evolutionary rescue: It generates and it breaks up favorable gene combinations.
    Which of the two effects prevails depends on the fitness effects of mutations
    and on the impact of stochasticity on the allele frequencies. In this article,
    we analyze a mathematical model for rescue after a sudden environmental change
    when adaptation is contingent on mutations at two loci. The analysis reveals a
    complex nonlinear dependence of population survival on recombination. We moreover
    find that, counterintuitively, a fast eradication of the wild type can promote
    rescue in the presence of recombination. The model also shows that two-step rescue
    is not unlikely to happen and can even be more likely than single-step rescue
    (where adaptation relies on a single mutation), depending on the circumstances.'
acknowledgement: This work was made possible by a “For Women in Science” fellowship
  (L’Oréal Österreich in cooperation with the Austrian Commission for the United Nations
  Educational, Scientific, and Cultural Organization and the Austrian Academy of Sciences
  with financial support from the Federal Ministry for Science and Research Austria)
  and European Research Council grant 250152 (to Nick Barton).
article_processing_charge: No
author:
- first_name: Hildegard
  full_name: Uecker, Hildegard
  id: 2DB8F68A-F248-11E8-B48F-1D18A9856A87
  last_name: Uecker
  orcid: 0000-0001-9435-2813
- first_name: Joachim
  full_name: Hermisson, Joachim
  last_name: Hermisson
citation:
  ama: Uecker H, Hermisson J. The role of recombination in evolutionary rescue. <i>Genetics</i>.
    2016;202(2):721-732. doi:<a href="https://doi.org/10.1534/genetics.115.180299">10.1534/genetics.115.180299</a>
  apa: Uecker, H., &#38; Hermisson, J. (2016). The role of recombination in evolutionary
    rescue. <i>Genetics</i>. Genetics Society of America. <a href="https://doi.org/10.1534/genetics.115.180299">https://doi.org/10.1534/genetics.115.180299</a>
  chicago: Uecker, Hildegard, and Joachim Hermisson. “The Role of Recombination in
    Evolutionary Rescue.” <i>Genetics</i>. Genetics Society of America, 2016. <a href="https://doi.org/10.1534/genetics.115.180299">https://doi.org/10.1534/genetics.115.180299</a>.
  ieee: H. Uecker and J. Hermisson, “The role of recombination in evolutionary rescue,”
    <i>Genetics</i>, vol. 202, no. 2. Genetics Society of America, pp. 721–732, 2016.
  ista: Uecker H, Hermisson J. 2016. The role of recombination in evolutionary rescue.
    Genetics. 202(2), 721–732.
  mla: Uecker, Hildegard, and Joachim Hermisson. “The Role of Recombination in Evolutionary
    Rescue.” <i>Genetics</i>, vol. 202, no. 2, Genetics Society of America, 2016,
    pp. 721–32, doi:<a href="https://doi.org/10.1534/genetics.115.180299">10.1534/genetics.115.180299</a>.
  short: H. Uecker, J. Hermisson, Genetics 202 (2016) 721–732.
das_tickbox: '1'
date_created: 2018-12-11T11:50:54Z
date_published: 2016-02-01T00:00:00Z
date_updated: 2026-06-18T07:59:00Z
day: '01'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1534/genetics.115.180299
ec_funded: 1
intvolume: '       202'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://biorxiv.org/content/early/2015/07/06/022020.abstract
month: '02'
oa: 1
oa_version: Preprint
page: 721 - 732
project:
- _id: 25B07788-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '250152'
  name: Limits to selection in biology and in evolutionary computation
- _id: 25B67606-B435-11E9-9278-68D0E5697425
  name: L'OREAL Fellowship
publication: Genetics
publication_status: published
publisher: Genetics Society of America
publist_id: '6091'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The role of recombination in evolutionary rescue
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 202
year: '2016'
...
---
_id: '12196'
abstract:
- lang: eng
  text: SNC1 (SUPPRESSOR OF NPR1, CONSTITUTIVE 1) is one of a suite of intracellular
    Arabidopsis NOD-like receptor (NLR) proteins which, upon activation, result in
    the induction of defense responses. However, the molecular mechanisms underlying
    NLR activation and the subsequent provocation of immune responses are only partially
    characterized. To identify negative regulators of NLR-mediated immunity, a forward
    genetic screen was undertaken to search for enhancers of the dwarf, autoimmune
    gain-of-function snc1 mutant. To avoid lethality resulting from severe dwarfism,
    the screen was conducted using mos4 (modifier of snc1, 4) snc1 plants, which display
    wild-type-like morphology and resistance. M2 progeny were screened for mutant,
    snc1-enhancing (muse) mutants displaying a reversion to snc1-like phenotypes.
    The muse9 mos4 snc1 triple mutant was found to exhibit dwarf morphology, elevated
    expression of the pPR2-GUS defense marker reporter gene and enhanced resistance
    to the oomycete pathogen Hyaloperonospora arabidopsidis Noco2. Via map-based cloning
    and Illumina sequencing, it was determined that the muse9 mutation is in the gene
    encoding the SWI/SNF chromatin remodeler SYD (SPLAYED), and was thus renamed syd-10.
    The syd-10 single mutant has no observable alteration from wild-type-like resistance,
    although the syd-4 T-DNA insertion allele displays enhanced resistance to the
    bacterial pathogen Pseudomonas syringae pv. maculicola ES4326. Transcription of
    SNC1 is increased in both syd-4 and syd-10. These data suggest that SYD plays
    a subtle, specific role in the regulation of SNC1 expression and SNC1-mediated
    immunity. SYD may work with other proteins at the chromatin level to repress SNC1
    transcription; such regulation is important for fine-tuning the expression of
    NLR-encoding genes to prevent unpropitious autoimmunity.
acknowledgement: "This work was supported by the National Sciences and Engineering
  Research Council of Canada [Canada Graduate\r\nScholarship–Doctoral to K.J.; Discovery
  Grant to X.L.]; the department of Botany at the University of f British Columbia\r\n[the
  Dewar Cooper Memorial Fund to X.L.].The authors would like to thank Dr. Yuelin Zhang
  and Ms. Yan Li for their assistance with next-generation sequencing, and Mr. Charles
  Copeland for critical reading of the manuscript."
article_processing_charge: No
article_type: original
author:
- first_name: Kaeli C.M.
  full_name: Johnson, Kaeli C.M.
  last_name: Johnson
- first_name: Shitou
  full_name: Xia, Shitou
  last_name: Xia
- first_name: Xiaoqi
  full_name: Feng, Xiaoqi
  id: e0164712-22ee-11ed-b12a-d80fcdf35958
  last_name: Feng
  orcid: 0000-0002-4008-1234
- first_name: Xin
  full_name: Li, Xin
  last_name: Li
citation:
  ama: Johnson KCM, Xia S, Feng X, Li X. The chromatin remodeler SPLAYED negatively
    regulates SNC1-mediated immunity. <i>Plant and Cell Physiology</i>. 2015;56(8):1616-1623.
    doi:<a href="https://doi.org/10.1093/pcp/pcv087">10.1093/pcp/pcv087</a>
  apa: Johnson, K. C. M., Xia, S., Feng, X., &#38; Li, X. (2015). The chromatin remodeler
    SPLAYED negatively regulates SNC1-mediated immunity. <i>Plant and Cell Physiology</i>.
    Oxford University Press. <a href="https://doi.org/10.1093/pcp/pcv087">https://doi.org/10.1093/pcp/pcv087</a>
  chicago: Johnson, Kaeli C.M., Shitou Xia, Xiaoqi Feng, and Xin Li. “The Chromatin
    Remodeler SPLAYED Negatively Regulates SNC1-Mediated Immunity.” <i>Plant and Cell
    Physiology</i>. Oxford University Press, 2015. <a href="https://doi.org/10.1093/pcp/pcv087">https://doi.org/10.1093/pcp/pcv087</a>.
  ieee: K. C. M. Johnson, S. Xia, X. Feng, and X. Li, “The chromatin remodeler SPLAYED
    negatively regulates SNC1-mediated immunity,” <i>Plant and Cell Physiology</i>,
    vol. 56, no. 8. Oxford University Press, pp. 1616–1623, 2015.
  ista: Johnson KCM, Xia S, Feng X, Li X. 2015. The chromatin remodeler SPLAYED negatively
    regulates SNC1-mediated immunity. Plant and Cell Physiology. 56(8), 1616–1623.
  mla: Johnson, Kaeli C. M., et al. “The Chromatin Remodeler SPLAYED Negatively Regulates
    SNC1-Mediated Immunity.” <i>Plant and Cell Physiology</i>, vol. 56, no. 8, Oxford
    University Press, 2015, pp. 1616–23, doi:<a href="https://doi.org/10.1093/pcp/pcv087">10.1093/pcp/pcv087</a>.
  short: K.C.M. Johnson, S. Xia, X. Feng, X. Li, Plant and Cell Physiology 56 (2015)
    1616–1623.
date_created: 2023-01-16T09:20:22Z
date_published: 2015-08-01T00:00:00Z
date_updated: 2023-05-08T11:03:23Z
department:
- _id: XiFe
doi: 10.1093/pcp/pcv087
extern: '1'
external_id:
  pmid:
  - '26063389'
intvolume: '        56'
issue: '8'
keyword:
- Cell Biology
- Plant Science
- Physiology
- General Medicine
language:
- iso: eng
month: '08'
oa_version: None
page: 1616-1623
pmid: 1
publication: Plant and Cell Physiology
publication_identifier:
  issn:
  - 0032-0781
  - 1471-9053
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: The chromatin remodeler SPLAYED negatively regulates SNC1-mediated immunity
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 56
year: '2015'
...
---
_id: '12626'
abstract:
- lang: eng
  text: Ice cliffs have been identified as a reason for higher ablation rates on debris-covered
    glaciers than are implied by the insulation effects of the debris. This study
    aims to improve our understanding of cliff backwasting, and the role of radiative
    fluxes in particular. An energy-balance model is forced with new data gathered
    in May and October 2013 on Lirung Glacier, Nepalese Himalaya. Observations show
    substantial variability in melt between cliffs, between locations on any cliff
    and between seasons. Using a high-resolution digital elevation model we calculate
    longwave fluxes incident to the cliff from surrounding terrain and include the
    effect of local shading on shortwave radiation. This is an advance over previous
    studies, that made simplified assumptions on cliff geometry and radiative fluxes.
    Measured melt rates varied between 3.25 and 8.6 cm d−1 in May and 0.18 and 1.34
    cm d−1 in October. Model results reproduce the strong variability in space and
    time, suggesting considerable differences in radiative fluxes over one cliff.
    In October the model fails to reproduce stake readings, probably due to the lack
    of a refreezing component. Disregarding local topography can lead to overestimation
    of melt at the point scale by up to ∼9%.
article_processing_charge: No
article_type: original
author:
- first_name: Jakob F.
  full_name: Steiner, Jakob F.
  last_name: Steiner
- first_name: Francesca
  full_name: Pellicciotti, Francesca
  id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
  last_name: Pellicciotti
- first_name: Pascal
  full_name: Buri, Pascal
  last_name: Buri
- first_name: Evan S.
  full_name: Miles, Evan S.
  last_name: Miles
- first_name: Walter W.
  full_name: Immerzeel, Walter W.
  last_name: Immerzeel
- first_name: Tim D.
  full_name: Reid, Tim D.
  last_name: Reid
citation:
  ama: Steiner JF, Pellicciotti F, Buri P, Miles ES, Immerzeel WW, Reid TD. Modelling
    ice-cliff backwasting on a debris-covered glacier in the Nepalese Himalaya. <i>Journal
    of Glaciology</i>. 2015;61(229):889-907. doi:<a href="https://doi.org/10.3189/2015jog14j194">10.3189/2015jog14j194</a>
  apa: Steiner, J. F., Pellicciotti, F., Buri, P., Miles, E. S., Immerzeel, W. W.,
    &#38; Reid, T. D. (2015). Modelling ice-cliff backwasting on a debris-covered
    glacier in the Nepalese Himalaya. <i>Journal of Glaciology</i>. International
    Glaciological Society. <a href="https://doi.org/10.3189/2015jog14j194">https://doi.org/10.3189/2015jog14j194</a>
  chicago: Steiner, Jakob F., Francesca Pellicciotti, Pascal Buri, Evan S. Miles,
    Walter W. Immerzeel, and Tim D. Reid. “Modelling Ice-Cliff Backwasting on a Debris-Covered
    Glacier in the Nepalese Himalaya.” <i>Journal of Glaciology</i>. International
    Glaciological Society, 2015. <a href="https://doi.org/10.3189/2015jog14j194">https://doi.org/10.3189/2015jog14j194</a>.
  ieee: J. F. Steiner, F. Pellicciotti, P. Buri, E. S. Miles, W. W. Immerzeel, and
    T. D. Reid, “Modelling ice-cliff backwasting on a debris-covered glacier in the
    Nepalese Himalaya,” <i>Journal of Glaciology</i>, vol. 61, no. 229. International
    Glaciological Society, pp. 889–907, 2015.
  ista: Steiner JF, Pellicciotti F, Buri P, Miles ES, Immerzeel WW, Reid TD. 2015.
    Modelling ice-cliff backwasting on a debris-covered glacier in the Nepalese Himalaya.
    Journal of Glaciology. 61(229), 889–907.
  mla: Steiner, Jakob F., et al. “Modelling Ice-Cliff Backwasting on a Debris-Covered
    Glacier in the Nepalese Himalaya.” <i>Journal of Glaciology</i>, vol. 61, no.
    229, International Glaciological Society, 2015, pp. 889–907, doi:<a href="https://doi.org/10.3189/2015jog14j194">10.3189/2015jog14j194</a>.
  short: J.F. Steiner, F. Pellicciotti, P. Buri, E.S. Miles, W.W. Immerzeel, T.D.
    Reid, Journal of Glaciology 61 (2015) 889–907.
date_created: 2023-02-20T08:16:01Z
date_published: 2015-07-01T00:00:00Z
date_updated: 2023-02-24T09:43:14Z
day: '01'
doi: 10.3189/2015jog14j194
extern: '1'
intvolume: '        61'
issue: '229'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.3189/2015JoG14J194
month: '07'
oa: 1
oa_version: Published Version
page: 889-907
publication: Journal of Glaciology
publication_identifier:
  eissn:
  - 1727-5652
  issn:
  - 0022-1430
publication_status: published
publisher: International Glaciological Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Modelling ice-cliff backwasting on a debris-covered glacier in the Nepalese
  Himalaya
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 61
year: '2015'
...
---
_id: '12627'
abstract:
- lang: eng
  text: Spatial evolution of supraglacial debris cover on mountain glaciers is a largely
    unmonitored and poorly understood phenomenon that directly affects glacier melt.
    Supraglacial debris cover for 93 glaciers in the Karakoram, northern Pakistan,
    was mapped from Landsat imagery acquired in 1977, 1998, 2009 and 2014. Surge-type
    glaciers occupy 41% of the study area and were considered separately. The time
    series of debris-covered surface area change shows a mean value of zero or near-zero
    change for both surging and non-surging glaciers. An increase in debris-covered
    area is often associated with negative regional mass balances. We extend this
    logic to suggest that the stable regional mass balances in the Karakoram explain
    the zero or near-zero change in debris-covered area. This coupling of trends combined
    with our 37 year time series of data suggests the Karakoram anomaly extends further
    back in time than previously known.
article_processing_charge: No
article_type: original
author:
- first_name: Sam
  full_name: Herreid, Sam
  last_name: Herreid
- first_name: Francesca
  full_name: Pellicciotti, Francesca
  id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
  last_name: Pellicciotti
- first_name: Alvaro
  full_name: Ayala, Alvaro
  last_name: Ayala
- first_name: Anna
  full_name: Chesnokova, Anna
  last_name: Chesnokova
- first_name: Christian
  full_name: Kienholz, Christian
  last_name: Kienholz
- first_name: Joseph
  full_name: Shea, Joseph
  last_name: Shea
- first_name: Arun
  full_name: Shrestha, Arun
  last_name: Shrestha
citation:
  ama: Herreid S, Pellicciotti F, Ayala A, et al. Satellite observations show no net
    change in the percentage of supraglacial debris-covered area in northern Pakistan
    from 1977 to 2014. <i>Journal of Glaciology</i>. 2015;61(227):524-536. doi:<a
    href="https://doi.org/10.3189/2015jog14j227">10.3189/2015jog14j227</a>
  apa: Herreid, S., Pellicciotti, F., Ayala, A., Chesnokova, A., Kienholz, C., Shea,
    J., &#38; Shrestha, A. (2015). Satellite observations show no net change in the
    percentage of supraglacial debris-covered area in northern Pakistan from 1977
    to 2014. <i>Journal of Glaciology</i>. International Glaciological Society. <a
    href="https://doi.org/10.3189/2015jog14j227">https://doi.org/10.3189/2015jog14j227</a>
  chicago: Herreid, Sam, Francesca Pellicciotti, Alvaro Ayala, Anna Chesnokova, Christian
    Kienholz, Joseph Shea, and Arun Shrestha. “Satellite Observations Show No Net
    Change in the Percentage of Supraglacial Debris-Covered Area in Northern Pakistan
    from 1977 to 2014.” <i>Journal of Glaciology</i>. International Glaciological
    Society, 2015. <a href="https://doi.org/10.3189/2015jog14j227">https://doi.org/10.3189/2015jog14j227</a>.
  ieee: S. Herreid <i>et al.</i>, “Satellite observations show no net change in the
    percentage of supraglacial debris-covered area in northern Pakistan from 1977
    to 2014,” <i>Journal of Glaciology</i>, vol. 61, no. 227. International Glaciological
    Society, pp. 524–536, 2015.
  ista: Herreid S, Pellicciotti F, Ayala A, Chesnokova A, Kienholz C, Shea J, Shrestha
    A. 2015. Satellite observations show no net change in the percentage of supraglacial
    debris-covered area in northern Pakistan from 1977 to 2014. Journal of Glaciology.
    61(227), 524–536.
  mla: Herreid, Sam, et al. “Satellite Observations Show No Net Change in the Percentage
    of Supraglacial Debris-Covered Area in Northern Pakistan from 1977 to 2014.” <i>Journal
    of Glaciology</i>, vol. 61, no. 227, International Glaciological Society, 2015,
    pp. 524–36, doi:<a href="https://doi.org/10.3189/2015jog14j227">10.3189/2015jog14j227</a>.
  short: S. Herreid, F. Pellicciotti, A. Ayala, A. Chesnokova, C. Kienholz, J. Shea,
    A. Shrestha, Journal of Glaciology 61 (2015) 524–536.
date_created: 2023-02-20T08:16:06Z
date_published: 2015-05-01T00:00:00Z
date_updated: 2023-02-24T09:40:30Z
day: '01'
doi: 10.3189/2015jog14j227
extern: '1'
intvolume: '        61'
issue: '227'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.3189/2015JoG14J227
month: '05'
oa: 1
oa_version: Published Version
page: 524-536
publication: Journal of Glaciology
publication_identifier:
  eissn:
  - 1727-5652
  issn:
  - 0022-1430
publication_status: published
publisher: International Glaciological Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Satellite observations show no net change in the percentage of supraglacial
  debris-covered area in northern Pakistan from 1977 to 2014
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 61
year: '2015'
...
---
_id: '12628'
abstract:
- lang: eng
  text: Thick debris cover on glaciers can significantly reduce ice melt. However,
    several studies have suggested that debris-covered glaciers in the Himalaya might
    have lost mass at a rate similar to debris-free glaciers. We reconstruct elevation
    and mass changes for the debris-covered glaciers of the upper Langtang valley,
    Nepalese Himalaya, using a digital elevation model (DEM) from 1974 stereo Hexagon
    satellite data and the 2000 SRTM (Shuttle Radar Topography Mission) DEM. Uncertainties
    are high in the accumulation areas, due to data gaps in the SRTM and difficulties
    with delineation of the glacier borders. Even with these uncertainties, we obtain
    thinning rates comparable to those of several other studies in the Himalaya. In
    particular, we obtain a total mass balance for the investigated debris-covered
    glaciers of the basin of –0.32 ± 0.18 m w.e. a<jats:sup>−1</jats:sup>. However,
    there are major spatial differences both between glaciers and within any single
    glacier, exhibiting a very distinct nonlinear mass-balance profile with elevation.
    Through analysis of surface velocities derived from Landsat ETM+ imagery, we show
    that thinning occurs in areas of low velocity and low slope. These areas are prone
    to a general, dynamic decay of surface features and to the development of supraglacial
    lakes and ice cliffs, which may be responsible for a considerable increase in
    overall glacier ablation.
article_processing_charge: No
article_type: original
author:
- first_name: Francesca
  full_name: Pellicciotti, Francesca
  id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
  last_name: Pellicciotti
- first_name: Christa
  full_name: Stephan, Christa
  last_name: Stephan
- first_name: Evan
  full_name: Miles, Evan
  last_name: Miles
- first_name: Sam
  full_name: Herreid, Sam
  last_name: Herreid
- first_name: Walter W.
  full_name: Immerzeel, Walter W.
  last_name: Immerzeel
- first_name: Tobias
  full_name: Bolch, Tobias
  last_name: Bolch
citation:
  ama: Pellicciotti F, Stephan C, Miles E, Herreid S, Immerzeel WW, Bolch T. Mass-balance
    changes of the debris-covered glaciers in the Langtang Himal, Nepal, from 1974
    to 1999. <i>Journal of Glaciology</i>. 2015;61(226):373-386. doi:<a href="https://doi.org/10.3189/2015jog13j237">10.3189/2015jog13j237</a>
  apa: Pellicciotti, F., Stephan, C., Miles, E., Herreid, S., Immerzeel, W. W., &#38;
    Bolch, T. (2015). Mass-balance changes of the debris-covered glaciers in the Langtang
    Himal, Nepal, from 1974 to 1999. <i>Journal of Glaciology</i>. International Glaciological
    Society. <a href="https://doi.org/10.3189/2015jog13j237">https://doi.org/10.3189/2015jog13j237</a>
  chicago: Pellicciotti, Francesca, Christa Stephan, Evan Miles, Sam Herreid, Walter
    W. Immerzeel, and Tobias Bolch. “Mass-Balance Changes of the Debris-Covered Glaciers
    in the Langtang Himal, Nepal, from 1974 to 1999.” <i>Journal of Glaciology</i>.
    International Glaciological Society, 2015. <a href="https://doi.org/10.3189/2015jog13j237">https://doi.org/10.3189/2015jog13j237</a>.
  ieee: F. Pellicciotti, C. Stephan, E. Miles, S. Herreid, W. W. Immerzeel, and T.
    Bolch, “Mass-balance changes of the debris-covered glaciers in the Langtang Himal,
    Nepal, from 1974 to 1999,” <i>Journal of Glaciology</i>, vol. 61, no. 226. International
    Glaciological Society, pp. 373–386, 2015.
  ista: Pellicciotti F, Stephan C, Miles E, Herreid S, Immerzeel WW, Bolch T. 2015.
    Mass-balance changes of the debris-covered glaciers in the Langtang Himal, Nepal,
    from 1974 to 1999. Journal of Glaciology. 61(226), 373–386.
  mla: Pellicciotti, Francesca, et al. “Mass-Balance Changes of the Debris-Covered
    Glaciers in the Langtang Himal, Nepal, from 1974 to 1999.” <i>Journal of Glaciology</i>,
    vol. 61, no. 226, International Glaciological Society, 2015, pp. 373–86, doi:<a
    href="https://doi.org/10.3189/2015jog13j237">10.3189/2015jog13j237</a>.
  short: F. Pellicciotti, C. Stephan, E. Miles, S. Herreid, W.W. Immerzeel, T. Bolch,
    Journal of Glaciology 61 (2015) 373–386.
date_created: 2023-02-20T08:16:11Z
date_published: 2015-03-01T00:00:00Z
date_updated: 2023-02-24T09:35:21Z
day: '01'
doi: 10.3189/2015jog13j237
extern: '1'
intvolume: '        61'
issue: '226'
keyword:
- Earth-Surface Processes
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.3189/2015JoG13J237
month: '03'
oa: 1
oa_version: Published Version
page: 373-386
publication: Journal of Glaciology
publication_identifier:
  eissn:
  - 1727-5652
  issn:
  - 0022-1430
publication_status: published
publisher: International Glaciological Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Mass-balance changes of the debris-covered glaciers in the Langtang Himal,
  Nepal, from 1974 to 1999
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 61
year: '2015'
...
---
_id: '12629'
abstract:
- lang: eng
  text: Meteorological studies in high-mountain environments form the basis of our
    understanding of catchment hydrology and glacier accumulation and melt processes,
    yet high-altitude (>4000 m above sea level, asl) observatories are rare. This
    research presents meteorological data recorded between December 2012 and November
    2013 at seven stations in Nepal, ranging in elevation from 3860 to 5360 m asl.
    Seasonal and diurnal cycles in air temperature, vapour pressure, incoming short-wave
    and long-wave radiation, atmospheric transmissivity, wind speed, and precipitation
    are compared between sites. Solar radiation strongly affects diurnal temperature
    and vapour pressure cycles, but local topography and valley-scale circulations
    alter wind speed and precipitation cycles. The observed diurnal variability in
    vertical temperature gradients in all seasons highlights the importance of in
    situ measurements for melt modelling. The monsoon signal (progressive onset and
    sharp end) is visible in all data-sets, and the passage of the remnants of Typhoon
    Phailin in mid-October 2013 provides an interesting case study on the possible
    effects of such storms on glaciers in the region.
article_processing_charge: No
article_type: original
author:
- first_name: J.M.
  full_name: Shea, J.M.
  last_name: Shea
- first_name: P.
  full_name: Wagnon, P.
  last_name: Wagnon
- first_name: W.W.
  full_name: Immerzeel, W.W.
  last_name: Immerzeel
- first_name: R.
  full_name: Biron, R.
  last_name: Biron
- first_name: F.
  full_name: Brun, F.
  last_name: Brun
- first_name: Francesca
  full_name: Pellicciotti, Francesca
  id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
  last_name: Pellicciotti
citation:
  ama: Shea JM, Wagnon P, Immerzeel WW, Biron R, Brun F, Pellicciotti F. A comparative
    high-altitude meteorological analysis from three catchments in the Nepalese Himalaya.
    <i>International Journal of Water Resources Development</i>. 2015;31(2):174-200.
    doi:<a href="https://doi.org/10.1080/07900627.2015.1020417">10.1080/07900627.2015.1020417</a>
  apa: Shea, J. M., Wagnon, P., Immerzeel, W. W., Biron, R., Brun, F., &#38; Pellicciotti,
    F. (2015). A comparative high-altitude meteorological analysis from three catchments
    in the Nepalese Himalaya. <i>International Journal of Water Resources Development</i>.
    Taylor &#38; Francis. <a href="https://doi.org/10.1080/07900627.2015.1020417">https://doi.org/10.1080/07900627.2015.1020417</a>
  chicago: Shea, J.M., P. Wagnon, W.W. Immerzeel, R. Biron, F. Brun, and Francesca
    Pellicciotti. “A Comparative High-Altitude Meteorological Analysis from Three
    Catchments in the Nepalese Himalaya.” <i>International Journal of Water Resources
    Development</i>. Taylor &#38; Francis, 2015. <a href="https://doi.org/10.1080/07900627.2015.1020417">https://doi.org/10.1080/07900627.2015.1020417</a>.
  ieee: J. M. Shea, P. Wagnon, W. W. Immerzeel, R. Biron, F. Brun, and F. Pellicciotti,
    “A comparative high-altitude meteorological analysis from three catchments in
    the Nepalese Himalaya,” <i>International Journal of Water Resources Development</i>,
    vol. 31, no. 2. Taylor &#38; Francis, pp. 174–200, 2015.
  ista: Shea JM, Wagnon P, Immerzeel WW, Biron R, Brun F, Pellicciotti F. 2015. A
    comparative high-altitude meteorological analysis from three catchments in the
    Nepalese Himalaya. International Journal of Water Resources Development. 31(2),
    174–200.
  mla: Shea, J. M., et al. “A Comparative High-Altitude Meteorological Analysis from
    Three Catchments in the Nepalese Himalaya.” <i>International Journal of Water
    Resources Development</i>, vol. 31, no. 2, Taylor &#38; Francis, 2015, pp. 174–200,
    doi:<a href="https://doi.org/10.1080/07900627.2015.1020417">10.1080/07900627.2015.1020417</a>.
  short: J.M. Shea, P. Wagnon, W.W. Immerzeel, R. Biron, F. Brun, F. Pellicciotti,
    International Journal of Water Resources Development 31 (2015) 174–200.
date_created: 2023-02-20T08:16:17Z
date_published: 2015-04-18T00:00:00Z
date_updated: 2023-02-24T09:30:42Z
day: '18'
doi: 10.1080/07900627.2015.1020417
extern: '1'
intvolume: '        31'
issue: '2'
keyword:
- Water Science and Technology
- Development
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1080/07900627.2015.1020417
month: '04'
oa: 1
oa_version: Published Version
page: 174-200
publication: International Journal of Water Resources Development
publication_identifier:
  eissn:
  - 1360-0648
  issn:
  - 0790-0627
publication_status: published
publisher: Taylor & Francis
quality_controlled: '1'
scopus_import: '1'
status: public
title: A comparative high-altitude meteorological analysis from three catchments in
  the Nepalese Himalaya
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 31
year: '2015'
...
---
_id: '12630'
abstract:
- lang: eng
  text: "The hydrology of high-elevation watersheds of the Hindu Kush-Himalaya region
    (HKH) is poorly known. The correct representation of internal states and process
    dynamics in glacio-hydrological models can often not be verified due to missing
    in situ measurements. We use a new set of detailed ground data from the upper
    Langtang valley in Nepal to systematically guide a state-of-the art glacio-hydrological
    model through a parameter assigning process with the aim to understand the hydrology
    of the catchment and contribution of snow and ice processes to runoff. 14 parameters
    are directly calculated on the basis of local data, and 13 parameters are calibrated
    against 5 different datasets of in situ or remote sensing data. Spatial fields
    of debris thickness are reconstructed through a novel approach that employs data
    from an Unmanned Aerial Vehicle (UAV), energy balance modeling and statistical
    techniques. The model is validated against measured catchment runoff (Nash–Sutcliffe
    efficiency 0.87) and modeled snow cover is compared to Landsat snow cover. The
    advanced representation of processes allowed assessing the role played by avalanching
    for runoff for the first time for a Himalayan catchment (5% of annual water inputs
    to the hydrological system are due to snow redistribution) and to quantify the
    hydrological significance of sub-debris ice melt (9% of annual water inputs).
    Snowmelt is the most important contributor to total runoff during the hydrological
    year 2012/2013 (representing 40% of all sources), followed by rainfall (34%) and
    ice melt (26%). A sensitivity analysis is used to assess the efficiency of the
    monitoring network and identify the timing and location of field measurements
    that constrain model uncertainty. The methodology to set up a glacio-hydrological
    model in high-elevation regions presented in this study can be regarded as a benchmark
    for modelers in the HKH seeking to evaluate their calibration approach, their
    experimental setup and thus to reduce the predictive model uncertainty.\r\n\r\n"
article_processing_charge: No
article_type: original
author:
- first_name: S.
  full_name: Ragettli, S.
  last_name: Ragettli
- first_name: Francesca
  full_name: Pellicciotti, Francesca
  id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
  last_name: Pellicciotti
- first_name: W.W.
  full_name: Immerzeel, W.W.
  last_name: Immerzeel
- first_name: E.S.
  full_name: Miles, E.S.
  last_name: Miles
- first_name: L.
  full_name: Petersen, L.
  last_name: Petersen
- first_name: M.
  full_name: Heynen, M.
  last_name: Heynen
- first_name: J.M.
  full_name: Shea, J.M.
  last_name: Shea
- first_name: D.
  full_name: Stumm, D.
  last_name: Stumm
- first_name: S.
  full_name: Joshi, S.
  last_name: Joshi
- first_name: A.
  full_name: Shrestha, A.
  last_name: Shrestha
citation:
  ama: Ragettli S, Pellicciotti F, Immerzeel WW, et al. Unraveling the hydrology of
    a Himalayan catchment through integration of high resolution in situ data and
    remote sensing with an advanced simulation model. <i>Advances in Water Resources</i>.
    2015;78(4):94-111. doi:<a href="https://doi.org/10.1016/j.advwatres.2015.01.013">10.1016/j.advwatres.2015.01.013</a>
  apa: Ragettli, S., Pellicciotti, F., Immerzeel, W. W., Miles, E. S., Petersen, L.,
    Heynen, M., … Shrestha, A. (2015). Unraveling the hydrology of a Himalayan catchment
    through integration of high resolution in situ data and remote sensing with an
    advanced simulation model. <i>Advances in Water Resources</i>. Elsevier. <a href="https://doi.org/10.1016/j.advwatres.2015.01.013">https://doi.org/10.1016/j.advwatres.2015.01.013</a>
  chicago: Ragettli, S., Francesca Pellicciotti, W.W. Immerzeel, E.S. Miles, L. Petersen,
    M. Heynen, J.M. Shea, D. Stumm, S. Joshi, and A. Shrestha. “Unraveling the Hydrology
    of a Himalayan Catchment through Integration of High Resolution in Situ Data and
    Remote Sensing with an Advanced Simulation Model.” <i>Advances in Water Resources</i>.
    Elsevier, 2015. <a href="https://doi.org/10.1016/j.advwatres.2015.01.013">https://doi.org/10.1016/j.advwatres.2015.01.013</a>.
  ieee: S. Ragettli <i>et al.</i>, “Unraveling the hydrology of a Himalayan catchment
    through integration of high resolution in situ data and remote sensing with an
    advanced simulation model,” <i>Advances in Water Resources</i>, vol. 78, no. 4.
    Elsevier, pp. 94–111, 2015.
  ista: Ragettli S, Pellicciotti F, Immerzeel WW, Miles ES, Petersen L, Heynen M,
    Shea JM, Stumm D, Joshi S, Shrestha A. 2015. Unraveling the hydrology of a Himalayan
    catchment through integration of high resolution in situ data and remote sensing
    with an advanced simulation model. Advances in Water Resources. 78(4), 94–111.
  mla: Ragettli, S., et al. “Unraveling the Hydrology of a Himalayan Catchment through
    Integration of High Resolution in Situ Data and Remote Sensing with an Advanced
    Simulation Model.” <i>Advances in Water Resources</i>, vol. 78, no. 4, Elsevier,
    2015, pp. 94–111, doi:<a href="https://doi.org/10.1016/j.advwatres.2015.01.013">10.1016/j.advwatres.2015.01.013</a>.
  short: S. Ragettli, F. Pellicciotti, W.W. Immerzeel, E.S. Miles, L. Petersen, M.
    Heynen, J.M. Shea, D. Stumm, S. Joshi, A. Shrestha, Advances in Water Resources
    78 (2015) 94–111.
date_created: 2023-02-20T08:16:21Z
date_published: 2015-04-01T00:00:00Z
date_updated: 2023-02-24T09:28:04Z
day: '01'
doi: 10.1016/j.advwatres.2015.01.013
extern: '1'
intvolume: '        78'
issue: '4'
keyword:
- Water Science and Technology
language:
- iso: eng
month: '04'
oa_version: None
page: 94-111
publication: Advances in Water Resources
publication_identifier:
  issn:
  - 0309-1708
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Unraveling the hydrology of a Himalayan catchment through integration of high
  resolution in situ data and remote sensing with an advanced simulation model
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 78
year: '2015'
...
---
_id: '12631'
abstract:
- lang: eng
  text: Air temperature is one of the most relevant input variables for snow and ice
    melt calculations. However, local meteorological conditions, complex topography,
    and logistical concerns in glacierized regions make the measuring and modeling
    of air temperature a difficult task. In this study, we investigate the spatial
    distribution of 2 m air temperature over mountain glaciers and propose a modification
    to an existing model to improve its representation. Spatially distributed meteorological
    data from Haut Glacier d'Arolla (Switzerland), Place (Canada), and Juncal Norte
    (Chile) Glaciers are used to examine approximate flow line temperatures during
    their respective ablation seasons. During warm conditions (off-glacier temperatures
    well above 0°C), observed air temperatures in the upper reaches of Place Glacier
    and Haut Glacier d'Arolla decrease down glacier along the approximate flow line.
    At Juncal Norte and Haut Glacier d'Arolla, an increase in air temperature is observed
    over the glacier tongue. While the temperature behavior over the upper part can
    be explained by the cooling effect of the glacier surface, the temperature increase
    over the glacier tongue may be caused by several processes induced by the surrounding
    warm atmosphere. In order to capture the latter effect, we add an additional term
    to the Greuell and Böhm (GB) thermodynamic glacier wind model. For high off-glacier
    temperatures, the modified GB model reduces root-mean-square error up to 32% and
    provides a new approach for distributing air temperature over mountain glaciers
    as a function of off-glacier temperatures and approximate glacier flow lines.
article_processing_charge: No
article_type: original
author:
- first_name: A.
  full_name: Ayala, A.
  last_name: Ayala
- first_name: Francesca
  full_name: Pellicciotti, Francesca
  id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
  last_name: Pellicciotti
- first_name: J. M.
  full_name: Shea, J. M.
  last_name: Shea
citation:
  ama: 'Ayala A, Pellicciotti F, Shea JM. Modeling 2 m air temperatures over mountain
    glaciers: Exploring the influence of katabatic cooling and external warming. <i>Journal
    of Geophysical Research: Atmospheres</i>. 2015;120(8):3139-3157. doi:<a href="https://doi.org/10.1002/2015jd023137">10.1002/2015jd023137</a>'
  apa: 'Ayala, A., Pellicciotti, F., &#38; Shea, J. M. (2015). Modeling 2 m air temperatures
    over mountain glaciers: Exploring the influence of katabatic cooling and external
    warming. <i>Journal of Geophysical Research: Atmospheres</i>. American Geophysical
    Union. <a href="https://doi.org/10.1002/2015jd023137">https://doi.org/10.1002/2015jd023137</a>'
  chicago: 'Ayala, A., Francesca Pellicciotti, and J. M. Shea. “Modeling 2 m Air Temperatures
    over Mountain Glaciers: Exploring the Influence of Katabatic Cooling and External
    Warming.” <i>Journal of Geophysical Research: Atmospheres</i>. American Geophysical
    Union, 2015. <a href="https://doi.org/10.1002/2015jd023137">https://doi.org/10.1002/2015jd023137</a>.'
  ieee: 'A. Ayala, F. Pellicciotti, and J. M. Shea, “Modeling 2 m air temperatures
    over mountain glaciers: Exploring the influence of katabatic cooling and external
    warming,” <i>Journal of Geophysical Research: Atmospheres</i>, vol. 120, no. 8.
    American Geophysical Union, pp. 3139–3157, 2015.'
  ista: 'Ayala A, Pellicciotti F, Shea JM. 2015. Modeling 2 m air temperatures over
    mountain glaciers: Exploring the influence of katabatic cooling and external warming.
    Journal of Geophysical Research: Atmospheres. 120(8), 3139–3157.'
  mla: 'Ayala, A., et al. “Modeling 2 m Air Temperatures over Mountain Glaciers: Exploring
    the Influence of Katabatic Cooling and External Warming.” <i>Journal of Geophysical
    Research: Atmospheres</i>, vol. 120, no. 8, American Geophysical Union, 2015,
    pp. 3139–57, doi:<a href="https://doi.org/10.1002/2015jd023137">10.1002/2015jd023137</a>.'
  short: 'A. Ayala, F. Pellicciotti, J.M. Shea, Journal of Geophysical Research: Atmospheres
    120 (2015) 3139–3157.'
date_created: 2023-02-20T08:16:28Z
date_published: 2015-04-18T00:00:00Z
date_updated: 2023-02-24T09:16:26Z
day: '18'
doi: 10.1002/2015jd023137
extern: '1'
intvolume: '       120'
issue: '8'
keyword:
- Space and Planetary Science
- Earth and Planetary Sciences (miscellaneous)
- Atmospheric Science
- Geophysics
language:
- iso: eng
month: '04'
oa_version: Published Version
page: 3139-3157
publication: 'Journal of Geophysical Research: Atmospheres'
publication_identifier:
  eissn:
  - 2169-8996
  issn:
  - 2169-897X
publication_status: published
publisher: American Geophysical Union
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Modeling 2 m air temperatures over mountain glaciers: Exploring the influence
  of katabatic cooling and external warming'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 120
year: '2015'
...
---
_id: '12881'
acknowledgement: This work was supported by the DFG (SPP 1527) and the EU (FP7, REA
  grant no 291734).
article_processing_charge: No
author:
- first_name: Georg S
  full_name: Martius, Georg S
  id: 3A276B68-F248-11E8-B48F-1D18A9856A87
  last_name: Martius
- first_name: Eckehard
  full_name: Olbrich, Eckehard
  last_name: Olbrich
citation:
  ama: 'Martius GS, Olbrich E. Quantifying self-organizing behavior of autonomous
    robots. In: <i>Proceedings of the 13th European Conference on Artificial Life</i>.
    MIT Press; 2015:78. doi:<a href="https://doi.org/10.7551/978-0-262-33027-5-ch018">10.7551/978-0-262-33027-5-ch018</a>'
  apa: 'Martius, G. S., &#38; Olbrich, E. (2015). Quantifying self-organizing behavior
    of autonomous robots. In <i>Proceedings of the 13th European Conference on Artificial
    Life</i> (p. 78). York, United Kingdom: MIT Press. <a href="https://doi.org/10.7551/978-0-262-33027-5-ch018">https://doi.org/10.7551/978-0-262-33027-5-ch018</a>'
  chicago: Martius, Georg S, and Eckehard Olbrich. “Quantifying Self-Organizing Behavior
    of Autonomous Robots.” In <i>Proceedings of the 13th European Conference on Artificial
    Life</i>, 78. MIT Press, 2015. <a href="https://doi.org/10.7551/978-0-262-33027-5-ch018">https://doi.org/10.7551/978-0-262-33027-5-ch018</a>.
  ieee: G. S. Martius and E. Olbrich, “Quantifying self-organizing behavior of autonomous
    robots,” in <i>Proceedings of the 13th European Conference on Artificial Life</i>,
    York, United Kingdom, 2015, p. 78.
  ista: 'Martius GS, Olbrich E. 2015. Quantifying self-organizing behavior of autonomous
    robots. Proceedings of the 13th European Conference on Artificial Life. ECAL:
    European Conference on Artificial Life, 78.'
  mla: Martius, Georg S., and Eckehard Olbrich. “Quantifying Self-Organizing Behavior
    of Autonomous Robots.” <i>Proceedings of the 13th European Conference on Artificial
    Life</i>, MIT Press, 2015, p. 78, doi:<a href="https://doi.org/10.7551/978-0-262-33027-5-ch018">10.7551/978-0-262-33027-5-ch018</a>.
  short: G.S. Martius, E. Olbrich, in:, Proceedings of the 13th European Conference
    on Artificial Life, MIT Press, 2015, p. 78.
conference:
  end_date: 2015-07-24
  location: York, United Kingdom
  name: 'ECAL: European Conference on Artificial Life'
  start_date: 2015-07-20
date_created: 2023-04-30T22:01:07Z
date_published: 2015-07-01T00:00:00Z
date_updated: 2023-05-02T07:06:21Z
day: '01'
ddc:
- '000'
department:
- _id: ChLa
doi: 10.7551/978-0-262-33027-5-ch018
ec_funded: 1
file:
- access_level: open_access
  checksum: 880eabe59c9df12f06a882aa1bc4e600
  content_type: application/pdf
  creator: dernst
  date_created: 2023-05-02T07:02:59Z
  date_updated: 2023-05-02T07:02:59Z
  file_id: '12882'
  file_name: 2015_ECAL_Martius.pdf
  file_size: 1674241
  relation: main_file
  success: 1
file_date_updated: 2023-05-02T07:02:59Z
has_accepted_license: '1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '07'
oa: 1
oa_version: Published Version
page: '78'
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
publication: Proceedings of the 13th European Conference on Artificial Life
publication_identifier:
  isbn:
  - '9780262330275'
publication_status: published
publisher: MIT Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Quantifying self-organizing behavior of autonomous robots
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '1311'
abstract:
- lang: eng
  text: In this paper, we develop an energy method to study finite speed of propagation
    and waiting time phenomena for the stochastic porous media equation with linear
    multiplicative noise in up to three spatial dimensions. Based on a novel iteration
    technique and on stochastic counterparts of weighted integral estimates used in
    the deterministic setting, we formulate a sufficient criterion on the growth of
    initial data which locally guarantees a waiting time phenomenon to occur almost
    surely. Up to a logarithmic factor, this criterion coincides with the optimal
    criterion known from the deterministic setting. Our technique can be modified
    to prove finite speed of propagation as well.
acknowledgement: The first author has been supported by the Lithuanian-Swiss co- operation
  program under the project agreement No. CH-SMM-01/0.
author:
- first_name: Julian L
  full_name: Julian Fischer
  id: 2C12A0B0-F248-11E8-B48F-1D18A9856A87
  last_name: Fischer
  orcid: 0000-0002-0479-558X
- first_name: Günther
  full_name: Grün, Günther
  last_name: Grün
citation:
  ama: 'Fischer JL, Grün G. Finite speed of propagation and waiting times for the
    stochastic porous medium equation: A unifying approach. <i>SIAM Journal on Mathematical
    Analysis</i>. 2015;47(1):825-854. doi:<a href="https://doi.org/10.1137/140960578">10.1137/140960578</a>'
  apa: 'Fischer, J. L., &#38; Grün, G. (2015). Finite speed of propagation and waiting
    times for the stochastic porous medium equation: A unifying approach. <i>SIAM
    Journal on Mathematical Analysis</i>. Society for Industrial and Applied Mathematics
    . <a href="https://doi.org/10.1137/140960578">https://doi.org/10.1137/140960578</a>'
  chicago: 'Fischer, Julian L, and Günther Grün. “Finite Speed of Propagation and
    Waiting Times for the Stochastic Porous Medium Equation: A Unifying Approach.”
    <i>SIAM Journal on Mathematical Analysis</i>. Society for Industrial and Applied
    Mathematics , 2015. <a href="https://doi.org/10.1137/140960578">https://doi.org/10.1137/140960578</a>.'
  ieee: 'J. L. Fischer and G. Grün, “Finite speed of propagation and waiting times
    for the stochastic porous medium equation: A unifying approach,” <i>SIAM Journal
    on Mathematical Analysis</i>, vol. 47, no. 1. Society for Industrial and Applied
    Mathematics , pp. 825–854, 2015.'
  ista: 'Fischer JL, Grün G. 2015. Finite speed of propagation and waiting times for
    the stochastic porous medium equation: A unifying approach. SIAM Journal on Mathematical
    Analysis. 47(1), 825–854.'
  mla: 'Fischer, Julian L., and Günther Grün. “Finite Speed of Propagation and Waiting
    Times for the Stochastic Porous Medium Equation: A Unifying Approach.” <i>SIAM
    Journal on Mathematical Analysis</i>, vol. 47, no. 1, Society for Industrial and
    Applied Mathematics , 2015, pp. 825–54, doi:<a href="https://doi.org/10.1137/140960578">10.1137/140960578</a>.'
  short: J.L. Fischer, G. Grün, SIAM Journal on Mathematical Analysis 47 (2015) 825–854.
date_created: 2018-12-11T11:51:18Z
date_published: 2015-01-01T00:00:00Z
date_updated: 2021-01-12T06:49:48Z
day: '01'
doi: 10.1137/140960578
extern: 1
intvolume: '        47'
issue: '1'
month: '01'
page: 825 - 854
publication: SIAM Journal on Mathematical Analysis
publication_status: published
publisher: 'Society for Industrial and Applied Mathematics '
publist_id: '5958'
quality_controlled: 0
status: public
title: 'Finite speed of propagation and waiting times for the stochastic porous medium
  equation: A unifying approach'
type: journal_article
volume: 47
year: '2015'
...
---
_id: '1313'
abstract:
- lang: eng
  text: We present an algorithm for the derivation of lower bounds on support propagation
    for a certain class of nonlinear parabolic equations. We proceed by combining
    the ideas in some recent papers by the author with the algorithmic construction
    of entropies due to Jüngel and Matthes, reducing the problem to a quantifier elimination
    problem. Due to its complexity, the quantifier elimination problem cannot be solved
    by present exact algorithms. However, by tackling the quantifier elimination problem
    numerically, in the case of the thin-film equation we are able to improve recent
    results by the author in the regime of strong slippage n ∈ (1, 2). For certain
    second-order doubly nonlinear parabolic equations, we are able to extend the known
    lower bounds on free boundary propagation to the case of irregular oscillatory
    initial data. Finally, we apply our method to a sixth-order quantum drift-diffusion
    equation, resulting in an upper bound on the time which it takes for the support
    to reach every point in the domain.
acknowledgement: This research was supported by the Lithuanian-Swiss cooperation program
  under the project agreement No.  CH-SMM-01/0.
author:
- first_name: Julian L
  full_name: Julian Fischer
  id: 2C12A0B0-F248-11E8-B48F-1D18A9856A87
  last_name: Fischer
  orcid: 0000-0002-0479-558X
citation:
  ama: 'Fischer JL. Estimates on front propagation for nonlinear higher-order parabolic
    equations: An algorithmic approach. <i>Interfaces and Free Boundaries</i>. 2015;17(1):1-20.
    doi:<a href="https://doi.org/10.4171/IFB/331">10.4171/IFB/331</a>'
  apa: 'Fischer, J. L. (2015). Estimates on front propagation for nonlinear higher-order
    parabolic equations: An algorithmic approach. <i>Interfaces and Free Boundaries</i>.
    European Mathematical Society Publishing House. <a href="https://doi.org/10.4171/IFB/331">https://doi.org/10.4171/IFB/331</a>'
  chicago: 'Fischer, Julian L. “Estimates on Front Propagation for Nonlinear Higher-Order
    Parabolic Equations: An Algorithmic Approach.” <i>Interfaces and Free Boundaries</i>.
    European Mathematical Society Publishing House, 2015. <a href="https://doi.org/10.4171/IFB/331">https://doi.org/10.4171/IFB/331</a>.'
  ieee: 'J. L. Fischer, “Estimates on front propagation for nonlinear higher-order
    parabolic equations: An algorithmic approach,” <i>Interfaces and Free Boundaries</i>,
    vol. 17, no. 1. European Mathematical Society Publishing House, pp. 1–20, 2015.'
  ista: 'Fischer JL. 2015. Estimates on front propagation for nonlinear higher-order
    parabolic equations: An algorithmic approach. Interfaces and Free Boundaries.
    17(1), 1–20.'
  mla: 'Fischer, Julian L. “Estimates on Front Propagation for Nonlinear Higher-Order
    Parabolic Equations: An Algorithmic Approach.” <i>Interfaces and Free Boundaries</i>,
    vol. 17, no. 1, European Mathematical Society Publishing House, 2015, pp. 1–20,
    doi:<a href="https://doi.org/10.4171/IFB/331">10.4171/IFB/331</a>.'
  short: J.L. Fischer, Interfaces and Free Boundaries 17 (2015) 1–20.
date_created: 2018-12-11T11:51:19Z
date_published: 2015-01-01T00:00:00Z
date_updated: 2021-01-12T06:49:48Z
day: '01'
doi: 10.4171/IFB/331
extern: 1
intvolume: '        17'
issue: '1'
month: '01'
page: 1 - 20
publication: Interfaces and Free Boundaries
publication_status: published
publisher: European Mathematical Society Publishing House
publist_id: '5956'
quality_controlled: 0
status: public
title: 'Estimates on front propagation for nonlinear higher-order parabolic equations:
  An algorithmic approach'
type: journal_article
volume: 17
year: '2015'
...
---
_id: '1314'
abstract:
- lang: eng
  text: 'We derive a posteriori estimates for the modeling error caused by the assumption
    of perfect incompressibility in the incompressible Navier-Stokes equation: Real
    fluids are never perfectly incompressible but always feature at least some low
    amount of compressibility. Thus, their behavior is described by the compressible
    Navier-Stokes equation, the pressure being a steep function of the density. We
    rigorously estimate the difference between an approximate solution to the incompressible
    Navier-Stokes equation and any weak solution to the compressible Navier-Stokes
    equation in the sense of Lions (without assuming any additional regularity of
    solutions). Heuristics and numerical results suggest that our error estimates
    are of optimal order in the case of &quot;well-behaved&quot; flows and divergence-free
    approximations of the velocity field. Thus, we expect our estimates to justify
    the idealization of fluids as perfectly incompressible also in practical situations.'
acknowledgement: The research of the author was supported by the Lithuanian-Swiss
  cooperation program under the project agreement CH-SMM-01/0.
author:
- first_name: Julian L
  full_name: Fischer, Julian L
  id: 2C12A0B0-F248-11E8-B48F-1D18A9856A87
  last_name: Fischer
  orcid: 0000-0002-0479-558X
citation:
  ama: Fischer JL. A posteriori modeling error estimates for the assumption of perfect
    incompressibility in the Navier-Stokes equation. <i>SIAM Journal on Numerical
    Analysis</i>. 2015;53(5):2178-2205. doi:<a href="https://doi.org/10.1137/140966654">10.1137/140966654</a>
  apa: Fischer, J. L. (2015). A posteriori modeling error estimates for the assumption
    of perfect incompressibility in the Navier-Stokes equation. <i>SIAM Journal on
    Numerical Analysis</i>. Society for Industrial and Applied Mathematics . <a href="https://doi.org/10.1137/140966654">https://doi.org/10.1137/140966654</a>
  chicago: Fischer, Julian L. “A Posteriori Modeling Error Estimates for the Assumption
    of Perfect Incompressibility in the Navier-Stokes Equation.” <i>SIAM Journal on
    Numerical Analysis</i>. Society for Industrial and Applied Mathematics , 2015.
    <a href="https://doi.org/10.1137/140966654">https://doi.org/10.1137/140966654</a>.
  ieee: J. L. Fischer, “A posteriori modeling error estimates for the assumption of
    perfect incompressibility in the Navier-Stokes equation,” <i>SIAM Journal on Numerical
    Analysis</i>, vol. 53, no. 5. Society for Industrial and Applied Mathematics ,
    pp. 2178–2205, 2015.
  ista: Fischer JL. 2015. A posteriori modeling error estimates for the assumption
    of perfect incompressibility in the Navier-Stokes equation. SIAM Journal on Numerical
    Analysis. 53(5), 2178–2205.
  mla: Fischer, Julian L. “A Posteriori Modeling Error Estimates for the Assumption
    of Perfect Incompressibility in the Navier-Stokes Equation.” <i>SIAM Journal on
    Numerical Analysis</i>, vol. 53, no. 5, Society for Industrial and Applied Mathematics
    , 2015, pp. 2178–205, doi:<a href="https://doi.org/10.1137/140966654">10.1137/140966654</a>.
  short: J.L. Fischer, SIAM Journal on Numerical Analysis 53 (2015) 2178–2205.
date_created: 2018-12-11T11:51:19Z
date_published: 2015-01-01T00:00:00Z
date_updated: 2021-01-12T06:49:49Z
day: '01'
doi: 10.1137/140966654
extern: '1'
intvolume: '        53'
issue: '5'
language:
- iso: eng
month: '01'
oa_version: None
page: 2178 - 2205
publication: SIAM Journal on Numerical Analysis
publication_status: published
publisher: 'Society for Industrial and Applied Mathematics '
publist_id: '5957'
quality_controlled: '1'
status: public
title: A posteriori modeling error estimates for the assumption of perfect incompressibility
  in the Navier-Stokes equation
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 53
year: '2015'
...
---
_id: '1316'
abstract:
- lang: eng
  text: In the present work we introduce the notion of a renormalized solution for
    reaction–diffusion systems with entropy-dissipating reactions. We establish the
    global existence of renormalized solutions. In the case of integrable reaction
    terms our notion of a renormalized solution reduces to the usual notion of a weak
    solution. Our existence result in particular covers all reaction–diffusion systems
    involving a single reversible reaction with mass-action kinetics and (possibly
    species-dependent) Fick-law diffusion; more generally, it covers the case of systems
    of reversible reactions with mass-action kinetics which satisfy the detailed balance
    condition. For such equations the existence of any kind of solution in general
    was an open problem, thereby motivating the study of renormalized solutions.
acknowledgement: This research was supported by the Lithuanian-Swiss cooperation program
  under the project agreement No. CH-SMM-01/0.
author:
- first_name: Julian L
  full_name: Julian Fischer
  id: 2C12A0B0-F248-11E8-B48F-1D18A9856A87
  last_name: Fischer
  orcid: 0000-0002-0479-558X
citation:
  ama: Fischer JL. Global existence of renormalized solutions to entropy-dissipating
    reaction–diffusion systems. <i>Archive for Rational Mechanics and Analysis</i>.
    2015;218(1):553-587. doi:<a href="https://doi.org/10.1007/s00205-015-0866-x">10.1007/s00205-015-0866-x</a>
  apa: Fischer, J. L. (2015). Global existence of renormalized solutions to entropy-dissipating
    reaction–diffusion systems. <i>Archive for Rational Mechanics and Analysis</i>.
    Springer. <a href="https://doi.org/10.1007/s00205-015-0866-x">https://doi.org/10.1007/s00205-015-0866-x</a>
  chicago: Fischer, Julian L. “Global Existence of Renormalized Solutions to Entropy-Dissipating
    Reaction–Diffusion Systems.” <i>Archive for Rational Mechanics and Analysis</i>.
    Springer, 2015. <a href="https://doi.org/10.1007/s00205-015-0866-x">https://doi.org/10.1007/s00205-015-0866-x</a>.
  ieee: J. L. Fischer, “Global existence of renormalized solutions to entropy-dissipating
    reaction–diffusion systems,” <i>Archive for Rational Mechanics and Analysis</i>,
    vol. 218, no. 1. Springer, pp. 553–587, 2015.
  ista: Fischer JL. 2015. Global existence of renormalized solutions to entropy-dissipating
    reaction–diffusion systems. Archive for Rational Mechanics and Analysis. 218(1),
    553–587.
  mla: Fischer, Julian L. “Global Existence of Renormalized Solutions to Entropy-Dissipating
    Reaction–Diffusion Systems.” <i>Archive for Rational Mechanics and Analysis</i>,
    vol. 218, no. 1, Springer, 2015, pp. 553–87, doi:<a href="https://doi.org/10.1007/s00205-015-0866-x">10.1007/s00205-015-0866-x</a>.
  short: J.L. Fischer, Archive for Rational Mechanics and Analysis 218 (2015) 553–587.
date_created: 2018-12-11T11:51:20Z
date_published: 2015-10-01T00:00:00Z
date_updated: 2021-01-12T06:49:50Z
day: '01'
doi: 10.1007/s00205-015-0866-x
extern: 1
intvolume: '       218'
issue: '1'
month: '10'
page: 553 - 587
publication: Archive for Rational Mechanics and Analysis
publication_status: published
publisher: Springer
publist_id: '5955'
quality_controlled: 0
status: public
title: Global existence of renormalized solutions to entropy-dissipating reaction–diffusion
  systems
type: journal_article
volume: 218
year: '2015'
...
---
_id: '8242'
article_number: AB101
article_processing_charge: No
article_type: original
author:
- first_name: Lukas
  full_name: Einhorn, Lukas
  last_name: Einhorn
- first_name: Judit
  full_name: Fazekas, Judit
  id: 36432834-F248-11E8-B48F-1D18A9856A87
  last_name: Fazekas
  orcid: 0000-0002-8777-3502
- first_name: Martina
  full_name: Muhr, Martina
  last_name: Muhr
- first_name: Alexandra
  full_name: Schoos, Alexandra
  last_name: Schoos
- first_name: Kumiko
  full_name: Oida, Kumiko
  last_name: Oida
- first_name: Josef
  full_name: Singer, Josef
  last_name: Singer
- first_name: Lucia
  full_name: Panakova, Lucia
  last_name: Panakova
- first_name: Krisztina
  full_name: Manzano-Szalai, Krisztina
  last_name: Manzano-Szalai
- first_name: Erika
  full_name: Jensen-Jarolim, Erika
  last_name: Jensen-Jarolim
citation:
  ama: Einhorn L, Singer J, Muhr M, et al. Generation of recombinant FcεRIα of dog,
    cat and horse for component-resolved allergy diagnosis in veterinary patients.
    <i>Journal of Allergy and Clinical Immunology</i>. 2015;135(2). doi:<a href="https://doi.org/10.1016/j.jaci.2014.12.1263">10.1016/j.jaci.2014.12.1263</a>
  apa: Einhorn, L., Singer, J., Muhr, M., Schoos, A., Oida, K., Singer, J., … Jensen-Jarolim,
    E. (2015). Generation of recombinant FcεRIα of dog, cat and horse for component-resolved
    allergy diagnosis in veterinary patients. <i>Journal of Allergy and Clinical Immunology</i>.
    Elsevier. <a href="https://doi.org/10.1016/j.jaci.2014.12.1263">https://doi.org/10.1016/j.jaci.2014.12.1263</a>
  chicago: Einhorn, Lukas, Judit Singer, Martina Muhr, Alexandra Schoos, Kumiko Oida,
    Josef Singer, Lucia Panakova, Krisztina Manzano-Szalai, and Erika Jensen-Jarolim.
    “Generation of Recombinant FcεRIα of Dog, Cat and Horse for Component-Resolved
    Allergy Diagnosis in Veterinary Patients.” <i>Journal of Allergy and Clinical
    Immunology</i>. Elsevier, 2015. <a href="https://doi.org/10.1016/j.jaci.2014.12.1263">https://doi.org/10.1016/j.jaci.2014.12.1263</a>.
  ieee: L. Einhorn <i>et al.</i>, “Generation of recombinant FcεRIα of dog, cat and
    horse for component-resolved allergy diagnosis in veterinary patients,” <i>Journal
    of Allergy and Clinical Immunology</i>, vol. 135, no. 2. Elsevier, 2015.
  ista: Einhorn L, Singer J, Muhr M, Schoos A, Oida K, Singer J, Panakova L, Manzano-Szalai
    K, Jensen-Jarolim E. 2015. Generation of recombinant FcεRIα of dog, cat and horse
    for component-resolved allergy diagnosis in veterinary patients. Journal of Allergy
    and Clinical Immunology. 135(2), AB101.
  mla: Einhorn, Lukas, et al. “Generation of Recombinant FcεRIα of Dog, Cat and Horse
    for Component-Resolved Allergy Diagnosis in Veterinary Patients.” <i>Journal of
    Allergy and Clinical Immunology</i>, vol. 135, no. 2, AB101, Elsevier, 2015, doi:<a
    href="https://doi.org/10.1016/j.jaci.2014.12.1263">10.1016/j.jaci.2014.12.1263</a>.
  short: L. Einhorn, J. Singer, M. Muhr, A. Schoos, K. Oida, J. Singer, L. Panakova,
    K. Manzano-Szalai, E. Jensen-Jarolim, Journal of Allergy and Clinical Immunology
    135 (2015).
date_created: 2020-08-10T11:54:09Z
date_published: 2015-02-01T00:00:00Z
date_updated: 2021-01-12T08:17:42Z
day: '01'
doi: 10.1016/j.jaci.2014.12.1263
extern: '1'
intvolume: '       135'
issue: '2'
language:
- iso: eng
month: '02'
oa_version: None
publication: Journal of Allergy and Clinical Immunology
publication_identifier:
  issn:
  - 0091-6749
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: Generation of recombinant FcεRIα of dog, cat and horse for component-resolved
  allergy diagnosis in veterinary patients
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 135
year: '2015'
...
---
_id: '832'
abstract:
- lang: eng
  text: Plants maintain capacity to form new organs such as leaves, flowers, lateral
    shoots and roots throughout their postembryonic lifetime. Lateral roots (LRs)
    originate from a few pericycle cells that acquire attributes of founder cells
    (FCs), undergo series of anticlinal divisions, and give rise to a few short initial
    cells. After initiation, coordinated cell division and differentiation occur,
    giving rise to lateral root primordia (LRP). Primordia continue to grow, emerge
    through the cortex and epidermal layers of the primary root, and finally a new
    apical meristem is established taking over the responsibility for growth of mature
    lateral roots [for detailed description of the individual stages of lateral root
    organogenesis see Malamy and Benfey (1997)]. To examine this highly dynamic developmental
    process and to investigate a role of various hormonal, genetic and environmental
    factors in the regulation of lateral root organogenesis, the real time imaging
    based analyses represent extremely powerful tools (Laskowski et al., 2008; De
    Smet et al., 2012; Marhavy et al., 2013 and 2014). Herein, we describe a protocol
    for real time lateral root primordia (LRP) analysis, which enables the monitoring
    of an onset of the specific gene expression and subcellular protein localization
    during primordia organogenesis, as well as the evaluation of the impact of genetic
    and environmental perturbations on LRP organogenesis.
acknowledgement: "European Research Council with a Starting Independent Research grant:
  ERC-2007-Stg-207362-HCPO, Czech Science Foundation: GA13-39982S\nWe thank Matyas
  Fendrych for critical reading and comments. The protocol was developed based on
  previously published work of De Rybel et al. (2010) and Laskowski et al. (2008). "
author:
- first_name: Peter
  full_name: Peter Marhavy
  id: 3F45B078-F248-11E8-B48F-1D18A9856A87
  last_name: Marhavy
  orcid: 0000-0001-5227-5741
- first_name: Eva
  full_name: Eva Benková
  id: 38F4F166-F248-11E8-B48F-1D18A9856A87
  last_name: Benková
  orcid: 0000-0002-8510-9739
citation:
  ama: Marhavý P, Benková E. Real time analysis of lateral root organogenesis in arabidopsis.
    <i>Bio-protocol</i>. 2015;5(8). doi:<a href="https://doi.org/10.21769/BioProtoc.1446">10.21769/BioProtoc.1446</a>
  apa: Marhavý, P., &#38; Benková, E. (2015). Real time analysis of lateral root organogenesis
    in arabidopsis. <i>Bio-Protocol</i>. Bio-protocol LLC. <a href="https://doi.org/10.21769/BioProtoc.1446">https://doi.org/10.21769/BioProtoc.1446</a>
  chicago: Marhavý, Peter, and Eva Benková. “Real Time Analysis of Lateral Root Organogenesis
    in Arabidopsis.” <i>Bio-Protocol</i>. Bio-protocol LLC, 2015. <a href="https://doi.org/10.21769/BioProtoc.1446">https://doi.org/10.21769/BioProtoc.1446</a>.
  ieee: P. Marhavý and E. Benková, “Real time analysis of lateral root organogenesis
    in arabidopsis,” <i>Bio-protocol</i>, vol. 5, no. 8. Bio-protocol LLC, 2015.
  ista: Marhavý P, Benková E. 2015. Real time analysis of lateral root organogenesis
    in arabidopsis. Bio-protocol. 5(8).
  mla: Marhavý, Peter, and Eva Benková. “Real Time Analysis of Lateral Root Organogenesis
    in Arabidopsis.” <i>Bio-Protocol</i>, vol. 5, no. 8, Bio-protocol LLC, 2015, doi:<a
    href="https://doi.org/10.21769/BioProtoc.1446">10.21769/BioProtoc.1446</a>.
  short: P. Marhavý, E. Benková, Bio-Protocol 5 (2015).
date_created: 2018-12-11T11:48:44Z
date_published: 2015-04-20T00:00:00Z
date_updated: 2021-01-12T08:18:07Z
day: '20'
doi: 10.21769/BioProtoc.1446
extern: 1
intvolume: '         5'
issue: '8'
month: '04'
publication: Bio-protocol
publication_status: published
publisher: Bio-protocol LLC
publist_id: '6816'
quality_controlled: 0
status: public
title: Real time analysis of lateral root organogenesis in arabidopsis
type: journal_article
volume: 5
year: '2015'
...
---
_id: '8456'
abstract:
- lang: eng
  text: The large majority of three-dimensional structures of biological macromolecules
    have been determined by X-ray diffraction of crystalline samples. High-resolution
    structure determination crucially depends on the homogeneity of the protein crystal.
    Overall ‘rocking’ motion of molecules in the crystal is expected to influence
    diffraction quality, and such motion may therefore affect the process of solving
    crystal structures. Yet, so far overall molecular motion has not directly been
    observed in protein crystals, and the timescale of such dynamics remains unclear.
    Here we use solid-state NMR, X-ray diffraction methods and μs-long molecular dynamics
    simulations to directly characterize the rigid-body motion of a protein in different
    crystal forms. For ubiquitin crystals investigated in this study we determine
    the range of possible correlation times of rocking motion, 0.1–100 μs. The amplitude
    of rocking varies from one crystal form to another and is correlated with the
    resolution obtainable in X-ray diffraction experiments.
article_number: '8361'
article_processing_charge: No
article_type: original
author:
- first_name: Peixiang
  full_name: Ma, Peixiang
  last_name: Ma
- first_name: Yi
  full_name: Xue, Yi
  last_name: Xue
- first_name: Nicolas
  full_name: Coquelle, Nicolas
  last_name: Coquelle
- first_name: Jens D.
  full_name: Haller, Jens D.
  last_name: Haller
- first_name: Tairan
  full_name: Yuwen, Tairan
  last_name: Yuwen
- first_name: Isabel
  full_name: Ayala, Isabel
  last_name: Ayala
- first_name: Oleg
  full_name: Mikhailovskii, Oleg
  last_name: Mikhailovskii
- first_name: Dieter
  full_name: Willbold, Dieter
  last_name: Willbold
- first_name: Jacques-Philippe
  full_name: Colletier, Jacques-Philippe
  last_name: Colletier
- first_name: Nikolai R.
  full_name: Skrynnikov, Nikolai R.
  last_name: Skrynnikov
- first_name: Paul
  full_name: Schanda, Paul
  id: 7B541462-FAF6-11E9-A490-E8DFE5697425
  last_name: Schanda
  orcid: 0000-0002-9350-7606
citation:
  ama: Ma P, Xue Y, Coquelle N, et al. Observing the overall rocking motion of a protein
    in a crystal. <i>Nature Communications</i>. 2015;6. doi:<a href="https://doi.org/10.1038/ncomms9361">10.1038/ncomms9361</a>
  apa: Ma, P., Xue, Y., Coquelle, N., Haller, J. D., Yuwen, T., Ayala, I., … Schanda,
    P. (2015). Observing the overall rocking motion of a protein in a crystal. <i>Nature
    Communications</i>. Springer Nature. <a href="https://doi.org/10.1038/ncomms9361">https://doi.org/10.1038/ncomms9361</a>
  chicago: Ma, Peixiang, Yi Xue, Nicolas Coquelle, Jens D. Haller, Tairan Yuwen, Isabel
    Ayala, Oleg Mikhailovskii, et al. “Observing the Overall Rocking Motion of a Protein
    in a Crystal.” <i>Nature Communications</i>. Springer Nature, 2015. <a href="https://doi.org/10.1038/ncomms9361">https://doi.org/10.1038/ncomms9361</a>.
  ieee: P. Ma <i>et al.</i>, “Observing the overall rocking motion of a protein in
    a crystal,” <i>Nature Communications</i>, vol. 6. Springer Nature, 2015.
  ista: Ma P, Xue Y, Coquelle N, Haller JD, Yuwen T, Ayala I, Mikhailovskii O, Willbold
    D, Colletier J-P, Skrynnikov NR, Schanda P. 2015. Observing the overall rocking
    motion of a protein in a crystal. Nature Communications. 6, 8361.
  mla: Ma, Peixiang, et al. “Observing the Overall Rocking Motion of a Protein in
    a Crystal.” <i>Nature Communications</i>, vol. 6, 8361, Springer Nature, 2015,
    doi:<a href="https://doi.org/10.1038/ncomms9361">10.1038/ncomms9361</a>.
  short: P. Ma, Y. Xue, N. Coquelle, J.D. Haller, T. Yuwen, I. Ayala, O. Mikhailovskii,
    D. Willbold, J.-P. Colletier, N.R. Skrynnikov, P. Schanda, Nature Communications
    6 (2015).
date_created: 2020-09-18T10:07:36Z
date_published: 2015-10-05T00:00:00Z
date_updated: 2021-01-12T08:19:24Z
day: '05'
doi: 10.1038/ncomms9361
extern: '1'
intvolume: '         6'
keyword:
- General Biochemistry
- Genetics and Molecular Biology
- General Physics and Astronomy
- General Chemistry
language:
- iso: eng
month: '10'
oa_version: Published Version
publication: Nature Communications
publication_identifier:
  issn:
  - 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Observing the overall rocking motion of a protein in a crystal
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2015'
...
---
_id: '8457'
abstract:
- lang: eng
  text: We review recent advances in methodologies to study microseconds‐to‐milliseconds
    exchange processes in biological molecules using magic‐angle spinning solid‐state
    nuclear magnetic resonance (MAS ssNMR) spectroscopy. The particularities of MAS
    ssNMR, as compared to solution‐state NMR, are elucidated using numerical simulations
    and experimental data. These simulations reveal the potential of MAS NMR to provide
    detailed insight into short‐lived conformations of biological molecules. Recent
    studies of conformational exchange dynamics in microcrystalline ubiquitin are
    discussed.
article_processing_charge: No
article_type: original
author:
- first_name: Peixiang
  full_name: Ma, Peixiang
  last_name: Ma
- first_name: Paul
  full_name: Schanda, Paul
  id: 7B541462-FAF6-11E9-A490-E8DFE5697425
  last_name: Schanda
  orcid: 0000-0002-9350-7606
citation:
  ama: 'Ma P, Schanda P. Conformational exchange processes in biological systems:
    Detection by solid-state NMR. <i>eMagRes</i>. 2015;4(3):699-708. doi:<a href="https://doi.org/10.1002/9780470034590.emrstm1418">10.1002/9780470034590.emrstm1418</a>'
  apa: 'Ma, P., &#38; Schanda, P. (2015). Conformational exchange processes in biological
    systems: Detection by solid-state NMR. <i>EMagRes</i>. Wiley. <a href="https://doi.org/10.1002/9780470034590.emrstm1418">https://doi.org/10.1002/9780470034590.emrstm1418</a>'
  chicago: 'Ma, Peixiang, and Paul Schanda. “Conformational Exchange Processes in
    Biological Systems: Detection by Solid-State NMR.” <i>EMagRes</i>. Wiley, 2015.
    <a href="https://doi.org/10.1002/9780470034590.emrstm1418">https://doi.org/10.1002/9780470034590.emrstm1418</a>.'
  ieee: 'P. Ma and P. Schanda, “Conformational exchange processes in biological systems:
    Detection by solid-state NMR,” <i>eMagRes</i>, vol. 4, no. 3. Wiley, pp. 699–708,
    2015.'
  ista: 'Ma P, Schanda P. 2015. Conformational exchange processes in biological systems:
    Detection by solid-state NMR. eMagRes. 4(3), 699–708.'
  mla: 'Ma, Peixiang, and Paul Schanda. “Conformational Exchange Processes in Biological
    Systems: Detection by Solid-State NMR.” <i>EMagRes</i>, vol. 4, no. 3, Wiley,
    2015, pp. 699–708, doi:<a href="https://doi.org/10.1002/9780470034590.emrstm1418">10.1002/9780470034590.emrstm1418</a>.'
  short: P. Ma, P. Schanda, EMagRes 4 (2015) 699–708.
date_created: 2020-09-18T10:07:45Z
date_published: 2015-09-10T00:00:00Z
date_updated: 2021-01-12T08:19:24Z
day: '10'
doi: 10.1002/9780470034590.emrstm1418
extern: '1'
intvolume: '         4'
issue: '3'
language:
- iso: eng
month: '09'
oa_version: None
page: 699-708
publication: eMagRes
publication_identifier:
  isbn:
  - '9780470034590'
  - '9780470058213'
publication_status: published
publisher: Wiley
quality_controlled: '1'
status: public
title: 'Conformational exchange processes in biological systems: Detection by solid-state
  NMR'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 4
year: '2015'
...
---
_id: '848'
abstract:
- lang: eng
  text: The nature of factors governing the tempo and mode of protein evolution is
    a fundamental issue in evolutionary biology. Specifically, whether or not interactions
    between different sites, or epistasis, are important in directing the course of
    evolution became one of the central questions. Several recent reports have scrutinized
    patterns of long-term protein evolution claiming them to be compatible only with
    an epistatic fitness landscape. However, these claims have not yet been substantiated
    with a formal model of protein evolution. Here, we formulate a simple covarion-like
    model of protein evolution focusing on the rate at which the fitness impact of
    amino acids at a site changes with time. We then apply the model to the data on
    convergent and divergent protein evolution to test whether or not the incorporation
    of epistatic interactions is necessary to explain the data. We find that convergent
    evolution cannot be explained without the incorporation of epistasis and the rate
    at which an amino acid state switches from being acceptable at a site to being
    deleterious is faster than the rate of amino acid substitution. Specifically,
    for proteins that have persisted in modern prokaryotic organisms since the last
    universal common ancestor for one amino acid substitution approximately ten amino
    acid states switch from being accessible to being deleterious, or vice versa.
    Thus, molecular evolution can only be perceived in the context of rapid turnover
    of which amino acids are available for evolution.
author:
- first_name: Dinara
  full_name: Usmanova, Dinara
  last_name: Usmanova
- first_name: Luca
  full_name: Ferretti, Luca
  last_name: Ferretti
- first_name: Inna
  full_name: Povolotskaya, Inna
  last_name: Povolotskaya
- first_name: Peter
  full_name: Vlasov, Peter
  last_name: Vlasov
- first_name: Fyodor
  full_name: Kondrashov, Fyodor
  id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
  last_name: Kondrashov
  orcid: 0000-0001-8243-4694
citation:
  ama: Usmanova D, Ferretti L, Povolotskaya I, Vlasov P, Kondrashov F. A model of
    substitution trajectories in sequence space and long-term protein evolution. <i>Molecular
    Biology and Evolution</i>. 2015;32(2):542-554. doi:<a href="https://doi.org/10.1093/molbev/msu318">10.1093/molbev/msu318</a>
  apa: Usmanova, D., Ferretti, L., Povolotskaya, I., Vlasov, P., &#38; Kondrashov,
    F. (2015). A model of substitution trajectories in sequence space and long-term
    protein evolution. <i>Molecular Biology and Evolution</i>. Oxford University Press.
    <a href="https://doi.org/10.1093/molbev/msu318">https://doi.org/10.1093/molbev/msu318</a>
  chicago: Usmanova, Dinara, Luca Ferretti, Inna Povolotskaya, Peter Vlasov, and Fyodor
    Kondrashov. “A Model of Substitution Trajectories in Sequence Space and Long-Term
    Protein Evolution.” <i>Molecular Biology and Evolution</i>. Oxford University
    Press, 2015. <a href="https://doi.org/10.1093/molbev/msu318">https://doi.org/10.1093/molbev/msu318</a>.
  ieee: D. Usmanova, L. Ferretti, I. Povolotskaya, P. Vlasov, and F. Kondrashov, “A
    model of substitution trajectories in sequence space and long-term protein evolution,”
    <i>Molecular Biology and Evolution</i>, vol. 32, no. 2. Oxford University Press,
    pp. 542–554, 2015.
  ista: Usmanova D, Ferretti L, Povolotskaya I, Vlasov P, Kondrashov F. 2015. A model
    of substitution trajectories in sequence space and long-term protein evolution.
    Molecular Biology and Evolution. 32(2), 542–554.
  mla: Usmanova, Dinara, et al. “A Model of Substitution Trajectories in Sequence
    Space and Long-Term Protein Evolution.” <i>Molecular Biology and Evolution</i>,
    vol. 32, no. 2, Oxford University Press, 2015, pp. 542–54, doi:<a href="https://doi.org/10.1093/molbev/msu318">10.1093/molbev/msu318</a>.
  short: D. Usmanova, L. Ferretti, I. Povolotskaya, P. Vlasov, F. Kondrashov, Molecular
    Biology and Evolution 32 (2015) 542–554.
date_created: 2018-12-11T11:48:49Z
date_published: 2015-02-01T00:00:00Z
date_updated: 2021-01-12T08:19:33Z
day: '01'
doi: 10.1093/molbev/msu318
extern: '1'
intvolume: '        32'
issue: '2'
language:
- iso: eng
month: '02'
oa_version: None
page: 542 - 554
publication: Molecular Biology and Evolution
publication_status: published
publisher: Oxford University Press
publist_id: '6804'
quality_controlled: '1'
status: public
title: A model of substitution trajectories in sequence space and long-term protein
  evolution
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 32
year: '2015'
...
---
_id: '8495'
abstract:
- lang: eng
  text: 'In this note, we consider the dynamics associated to a perturbation of an
    integrable Hamiltonian system in action-angle coordinates in any number of degrees
    of freedom and we prove the following result of ``micro-diffusion'''': under generic
    assumptions on $ h$ and $ f$, there exists an orbit of the system for which the
    drift of its action variables is at least of order $ \sqrt {\varepsilon }$, after
    a time of order $ \sqrt {\varepsilon }^{-1}$. The assumptions, which are essentially
    minimal, are that there exists a resonant point for $ h$ and that the corresponding
    averaged perturbation is non-constant. The conclusions, although very weak when
    compared to usual instability phenomena, are also essentially optimal within this
    setting.'
article_processing_charge: No
article_type: letter_note
author:
- first_name: Abed
  full_name: Bounemoura, Abed
  last_name: Bounemoura
- first_name: Vadim
  full_name: Kaloshin, Vadim
  id: FE553552-CDE8-11E9-B324-C0EBE5697425
  last_name: Kaloshin
  orcid: 0000-0002-6051-2628
citation:
  ama: Bounemoura A, Kaloshin V. A note on micro-instability for Hamiltonian systems
    close to integrable. <i>Proceedings of the American Mathematical Society</i>.
    2015;144(4):1553-1560. doi:<a href="https://doi.org/10.1090/proc/12796">10.1090/proc/12796</a>
  apa: Bounemoura, A., &#38; Kaloshin, V. (2015). A note on micro-instability for
    Hamiltonian systems close to integrable. <i>Proceedings of the American Mathematical
    Society</i>. American Mathematical Society. <a href="https://doi.org/10.1090/proc/12796">https://doi.org/10.1090/proc/12796</a>
  chicago: Bounemoura, Abed, and Vadim Kaloshin. “A Note on Micro-Instability for
    Hamiltonian Systems Close to Integrable.” <i>Proceedings of the American Mathematical
    Society</i>. American Mathematical Society, 2015. <a href="https://doi.org/10.1090/proc/12796">https://doi.org/10.1090/proc/12796</a>.
  ieee: A. Bounemoura and V. Kaloshin, “A note on micro-instability for Hamiltonian
    systems close to integrable,” <i>Proceedings of the American Mathematical Society</i>,
    vol. 144, no. 4. American Mathematical Society, pp. 1553–1560, 2015.
  ista: Bounemoura A, Kaloshin V. 2015. A note on micro-instability for Hamiltonian
    systems close to integrable. Proceedings of the American Mathematical Society.
    144(4), 1553–1560.
  mla: Bounemoura, Abed, and Vadim Kaloshin. “A Note on Micro-Instability for Hamiltonian
    Systems Close to Integrable.” <i>Proceedings of the American Mathematical Society</i>,
    vol. 144, no. 4, American Mathematical Society, 2015, pp. 1553–60, doi:<a href="https://doi.org/10.1090/proc/12796">10.1090/proc/12796</a>.
  short: A. Bounemoura, V. Kaloshin, Proceedings of the American Mathematical Society
    144 (2015) 1553–1560.
date_created: 2020-09-18T10:46:14Z
date_published: 2015-12-21T00:00:00Z
date_updated: 2021-01-12T08:19:40Z
day: '21'
doi: 10.1090/proc/12796
extern: '1'
intvolume: '       144'
issue: '4'
language:
- iso: eng
month: '12'
oa_version: None
page: 1553-1560
publication: Proceedings of the American Mathematical Society
publication_identifier:
  issn:
  - 0002-9939
  - 1088-6826
publication_status: published
publisher: American Mathematical Society
quality_controlled: '1'
status: public
title: A note on micro-instability for Hamiltonian systems close to integrable
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 144
year: '2015'
...
---
_id: '8498'
abstract:
- lang: eng
  text: "In the present note we announce a proof of a strong form of Arnold diffusion
    for smooth convex Hamiltonian systems. Let ${\\mathbb T}^2$  be a 2-dimensional
    torus and B2 be the unit ball around the origin in ${\\mathbb R}^2$ . Fix ρ >
    0. Our main result says that for a 'generic' time-periodic perturbation of an
    integrable system of two degrees of freedom $H_0(p)+\\varepsilon H_1(\\theta,p,t),\\quad
    \\ \\theta\\in {\\mathbb T}^2,\\ p\\in B^2,\\ t\\in {\\mathbb T}={\\mathbb R}/{\\mathbb
    Z}$ , with a strictly convex H0, there exists a ρ-dense orbit (θε, pε, t)(t) in
    ${\\mathbb T}^2 \\times B^2 \\times {\\mathbb T}$ , namely, a ρ-neighborhood of
    the orbit contains ${\\mathbb T}^2 \\times B^2 \\times {\\mathbb T}$ .\r\n\r\nOur
    proof is a combination of geometric and variational methods. The fundamental elements
    of the construction are the usage of crumpled normally hyperbolic invariant cylinders
    from [9], flower and simple normally hyperbolic invariant manifolds from [36]
    as well as their kissing property at a strong double resonance. This allows us
    to build a 'connected' net of three-dimensional normally hyperbolic invariant
    manifolds. To construct diffusing orbits along this net we employ a version of
    the Mather variational method [41] equipped with weak KAM theory [28], proposed
    by Bernard in [7]."
article_processing_charge: No
article_type: original
author:
- first_name: Vadim
  full_name: Kaloshin, Vadim
  id: FE553552-CDE8-11E9-B324-C0EBE5697425
  last_name: Kaloshin
  orcid: 0000-0002-6051-2628
- first_name: K
  full_name: Zhang, K
  last_name: Zhang
citation:
  ama: Kaloshin V, Zhang K. Arnold diffusion for smooth convex systems of two and
    a half degrees of freedom. <i>Nonlinearity</i>. 2015;28(8):2699-2720. doi:<a href="https://doi.org/10.1088/0951-7715/28/8/2699">10.1088/0951-7715/28/8/2699</a>
  apa: Kaloshin, V., &#38; Zhang, K. (2015). Arnold diffusion for smooth convex systems
    of two and a half degrees of freedom. <i>Nonlinearity</i>. IOP Publishing. <a
    href="https://doi.org/10.1088/0951-7715/28/8/2699">https://doi.org/10.1088/0951-7715/28/8/2699</a>
  chicago: Kaloshin, Vadim, and K Zhang. “Arnold Diffusion for Smooth Convex Systems
    of Two and a Half Degrees of Freedom.” <i>Nonlinearity</i>. IOP Publishing, 2015.
    <a href="https://doi.org/10.1088/0951-7715/28/8/2699">https://doi.org/10.1088/0951-7715/28/8/2699</a>.
  ieee: V. Kaloshin and K. Zhang, “Arnold diffusion for smooth convex systems of two
    and a half degrees of freedom,” <i>Nonlinearity</i>, vol. 28, no. 8. IOP Publishing,
    pp. 2699–2720, 2015.
  ista: Kaloshin V, Zhang K. 2015. Arnold diffusion for smooth convex systems of two
    and a half degrees of freedom. Nonlinearity. 28(8), 2699–2720.
  mla: Kaloshin, Vadim, and K. Zhang. “Arnold Diffusion for Smooth Convex Systems
    of Two and a Half Degrees of Freedom.” <i>Nonlinearity</i>, vol. 28, no. 8, IOP
    Publishing, 2015, pp. 2699–720, doi:<a href="https://doi.org/10.1088/0951-7715/28/8/2699">10.1088/0951-7715/28/8/2699</a>.
  short: V. Kaloshin, K. Zhang, Nonlinearity 28 (2015) 2699–2720.
date_created: 2020-09-18T10:46:43Z
date_published: 2015-06-30T00:00:00Z
date_updated: 2021-01-12T08:19:41Z
day: '30'
doi: 10.1088/0951-7715/28/8/2699
extern: '1'
intvolume: '        28'
issue: '8'
keyword:
- Mathematical Physics
- General Physics and Astronomy
- Applied Mathematics
- Statistical and Nonlinear Physics
language:
- iso: eng
month: '06'
oa_version: None
page: 2699-2720
publication: Nonlinearity
publication_identifier:
  issn:
  - 0951-7715
  - 1361-6544
publication_status: published
publisher: IOP Publishing
quality_controlled: '1'
status: public
title: Arnold diffusion for smooth convex systems of two and a half degrees of freedom
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 28
year: '2015'
...
