---
_id: '1613'
abstract:
- lang: eng
text: "In the last decade, induced pluripotent stem (iPS) cells have revolutionized
the utility of human in vitro models of neurological disease. The iPS-derived
and differentiated cells allow researchers to study the impact of a distinct cell
type in health and disease as well as performing therapeutic drug screens on a
human genetic background. In particular, clinical trials for Alzheimer's disease
(AD) have been often failing. Two of the potential reasons are first, the species
gap involved in proceeding from initial discoveries in rodent models to human
studies, and second, an unsatisfying patient stratification, meaning subgrouping
patients based on the disease severity due to the lack of phenotypic and genetic
markers. iPS cells overcome this obstacles and will improve our understanding
of disease subtypes in AD. They allow researchers conducting in depth characterization
of neural cells from both familial and sporadic AD patients as well as preclinical
screens on human cells.\r\n\r\nIn this review, we briefly outline the status quo
of iPS cell research in neurological diseases along with the general advantages
and pitfalls of these models. We summarize how genome-editing techniques such
as CRISPR/Cas will allow researchers to reduce the problem of genomic variability
inherent to human studies, followed by recent iPS cell studies relevant to AD.
We then focus on current techniques for the differentiation of iPS cells into
neural cell types that are relevant to AD research. Finally, we discuss how the
generation of three-dimensional cell culture systems will be important for understanding
AD phenotypes in a complex cellular milieu, and how both two- and three-dimensional
iPS cell models can provide platforms for drug discovery and translational studies
into the treatment of AD."
acknowledgement: This work was supported by NIH grant R01-AG047661 to LHT. The art
in Fig. 1 was created by Julian Wong.
author:
- first_name: Alison
full_name: Mungenast, Alison
last_name: Mungenast
- first_name: Sandra
full_name: Siegert, Sandra
id: 36ACD32E-F248-11E8-B48F-1D18A9856A87
last_name: Siegert
orcid: 0000-0001-8635-0877
- first_name: Li
full_name: Tsai, Li
last_name: Tsai
citation:
ama: Mungenast A, Siegert S, Tsai L. Modeling Alzheimer’s disease with human induced
pluripotent stem (iPS) cells. Molecular and Cellular Neuroscience. 2016;73:13-31.
doi:doi:10.1016/j.mcn.2015.11.010
apa: Mungenast, A., Siegert, S., & Tsai, L. (2016). Modeling Alzheimer’s disease
with human induced pluripotent stem (iPS) cells. Molecular and Cellular Neuroscience.
Academic Press. https://doi.org/doi:10.1016/j.mcn.2015.11.010
chicago: Mungenast, Alison, Sandra Siegert, and Li Tsai. “Modeling Alzheimer’s Disease
with Human Induced Pluripotent Stem (IPS) Cells.” Molecular and Cellular Neuroscience.
Academic Press, 2016. https://doi.org/doi:10.1016/j.mcn.2015.11.010.
ieee: A. Mungenast, S. Siegert, and L. Tsai, “Modeling Alzheimer’s disease with
human induced pluripotent stem (iPS) cells,” Molecular and Cellular Neuroscience,
vol. 73. Academic Press, pp. 13–31, 2016.
ista: Mungenast A, Siegert S, Tsai L. 2016. Modeling Alzheimer’s disease with human
induced pluripotent stem (iPS) cells. Molecular and Cellular Neuroscience. 73,
13–31.
mla: Mungenast, Alison, et al. “Modeling Alzheimer’s Disease with Human Induced
Pluripotent Stem (IPS) Cells.” Molecular and Cellular Neuroscience, vol.
73, Academic Press, 2016, pp. 13–31, doi:doi:10.1016/j.mcn.2015.11.010.
short: A. Mungenast, S. Siegert, L. Tsai, Molecular and Cellular Neuroscience 73
(2016) 13–31.
date_created: 2018-12-11T11:53:02Z
date_published: 2016-06-01T00:00:00Z
date_updated: 2021-01-12T06:52:00Z
day: '01'
ddc:
- '616'
doi: doi:10.1016/j.mcn.2015.11.010
extern: '1'
file:
- access_level: open_access
checksum: 620254114e04d5d6e7f37d15e4b8ace4
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:12:50Z
date_updated: 2020-07-14T12:45:07Z
file_id: '4970'
file_name: IST-2018-979-v1+1_Mungenast_2015_acceptedManuscript.pdf
file_size: 632915
relation: main_file
file_date_updated: 2020-07-14T12:45:07Z
has_accepted_license: '1'
intvolume: ' 73'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '06'
oa: 1
oa_version: Submitted Version
page: 13 - 31
publication: Molecular and Cellular Neuroscience
publication_status: published
publisher: Academic Press
publist_id: '5553'
pubrep_id: '979'
quality_controlled: '1'
status: public
title: Modeling Alzheimer's disease with human induced pluripotent stem (iPS) cells
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 73
year: '2016'
...
---
_id: '1306'
abstract:
- lang: eng
text: 'Resolving patterns of synaptic connectivity in neural circuits currently
requires serial section electron microscopy. However, complete circuit reconstruction
is prohibitively slow and may not be necessary for many purposes such as comparing
neuronal structure and connectivity among multiple animals. Here, we present an
alternative strategy, targeted reconstruction of specific neuronal types. We used
viral vectors to deliver peroxidase derivatives, which catalyze production of
an electron-dense tracer, to genetically identify neurons, and developed a protocol
that enhances the electron-density of the labeled cells while retaining the quality
of the ultrastructure. The high contrast of the marked neurons enabled two innovations
that speed data acquisition: targeted high-resolution reimaging of regions selected
from rapidly-acquired lower resolution reconstruction, and an unsupervised segmentation
algorithm. This pipeline reduces imaging and reconstruction times by two orders
of magnitude, facilitating directed inquiry of circuit motifs.'
acknowledgement: 'This work was supported by NIH grant NS76467 to MM, JL and JRS,
an HHMI Collaborative Innovation Award to JRS, an IARPA contract #D16PC00002 to
WJS and by The International Human Frontier Science Program Organization fellowship
to MJ.'
author:
- first_name: Maximilian A
full_name: Maximilian Jösch
id: 2BD278E6-F248-11E8-B48F-1D18A9856A87
last_name: Jösch
orcid: 0000-0002-3937-1330
- first_name: David
full_name: Mankus, David
last_name: Mankus
- first_name: Masahito
full_name: Yamagata, Masahito
last_name: Yamagata
- first_name: Ali
full_name: Shahbazi, Ali
last_name: Shahbazi
- first_name: Richard
full_name: Schalek, Richard L
last_name: Schalek
- first_name: Adi
full_name: Suissa-Peleg, Adi
last_name: Suissa Peleg
- first_name: Markus
full_name: Meister, Markus
last_name: Meister
- first_name: Jeff
full_name: Lichtman, Jeff W
last_name: Lichtman
- first_name: Walter
full_name: Scheirer, Walter J
last_name: Scheirer
- first_name: Joshua
full_name: Sanes, Joshua R
last_name: Sanes
citation:
ama: Jösch MA, Mankus D, Yamagata M, et al. Reconstruction of genetically identified
neurons imaged by serial-section electron microscopy. eLife. 2016;5(2016JULY).
doi:10.7554/eLife.15015
apa: Jösch, M. A., Mankus, D., Yamagata, M., Shahbazi, A., Schalek, R., Suissa Peleg,
A., … Sanes, J. (2016). Reconstruction of genetically identified neurons imaged
by serial-section electron microscopy. ELife. eLife Sciences Publications.
https://doi.org/10.7554/eLife.15015
chicago: Jösch, Maximilian A, David Mankus, Masahito Yamagata, Ali Shahbazi, Richard
Schalek, Adi Suissa Peleg, Markus Meister, Jeff Lichtman, Walter Scheirer, and
Joshua Sanes. “Reconstruction of Genetically Identified Neurons Imaged by Serial-Section
Electron Microscopy.” ELife. eLife Sciences Publications, 2016. https://doi.org/10.7554/eLife.15015.
ieee: M. A. Jösch et al., “Reconstruction of genetically identified neurons
imaged by serial-section electron microscopy,” eLife, vol. 5, no. 2016JULY.
eLife Sciences Publications, 2016.
ista: Jösch MA, Mankus D, Yamagata M, Shahbazi A, Schalek R, Suissa Peleg A, Meister
M, Lichtman J, Scheirer W, Sanes J. 2016. Reconstruction of genetically identified
neurons imaged by serial-section electron microscopy. eLife. 5(2016JULY).
mla: Jösch, Maximilian A., et al. “Reconstruction of Genetically Identified Neurons
Imaged by Serial-Section Electron Microscopy.” ELife, vol. 5, no. 2016JULY,
eLife Sciences Publications, 2016, doi:10.7554/eLife.15015.
short: M.A. Jösch, D. Mankus, M. Yamagata, A. Shahbazi, R. Schalek, A. Suissa Peleg,
M. Meister, J. Lichtman, W. Scheirer, J. Sanes, ELife 5 (2016).
date_created: 2018-12-11T11:51:16Z
date_published: 2016-07-07T00:00:00Z
date_updated: 2021-01-12T06:49:46Z
day: '07'
doi: 10.7554/eLife.15015
extern: 1
intvolume: ' 5'
issue: 2016JULY
license: https://creativecommons.org/licenses/by/4.0/
month: '07'
publication: eLife
publication_status: published
publisher: eLife Sciences Publications
publist_id: '5965'
quality_controlled: 0
status: public
title: Reconstruction of genetically identified neurons imaged by serial-section electron
microscopy
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
volume: 5
year: '2016'
...
---
_id: '1315'
abstract:
- lang: eng
text: We prove optimal second order convergence of a modified lowest-order Brezzi-Douglas-Marini
(BDM1) mixed finite element scheme for advection-diffusion problems in divergence
form. If advection is present, it is known that the total flux is approximated
only with first-order accuracy by the classical BDM1 mixed method, which is suboptimal
since the same order of convergence is obtained if the computationally less expensive
Raviart-Thomas (RT0) element is used. The modification that was first proposed
by Brunner et al. [Adv. Water Res., 35 (2012),pp. 163-171] is based on the hybrid
problem formulation and consists in using the Lagrange multipliers for the discretization
of the advective term instead of the cellwise constant approximation of the scalar
unknown.
author:
- first_name: Fabian
full_name: Brunner, Fabian
last_name: Brunner
- first_name: Julian L
full_name: Julian Fischer
id: 2C12A0B0-F248-11E8-B48F-1D18A9856A87
last_name: Fischer
orcid: 0000-0002-0479-558X
- first_name: Peter
full_name: Knabner, Peter
last_name: Knabner
citation:
ama: Brunner F, Fischer JL, Knabner P. Analysis of a modified second-order mixed
hybrid BDM1 finite element method for transport problems in divergence form. SIAM
Journal on Numerical Analysis. 2016;54(4):2359-2378. doi:10.1137/15M1035379
apa: Brunner, F., Fischer, J. L., & Knabner, P. (2016). Analysis of a modified
second-order mixed hybrid BDM1 finite element method for transport problems in
divergence form. SIAM Journal on Numerical Analysis. Society for Industrial
and Applied Mathematics . https://doi.org/10.1137/15M1035379
chicago: Brunner, Fabian, Julian L Fischer, and Peter Knabner. “Analysis of a Modified
Second-Order Mixed Hybrid BDM1 Finite Element Method for Transport Problems in
Divergence Form.” SIAM Journal on Numerical Analysis. Society for Industrial
and Applied Mathematics , 2016. https://doi.org/10.1137/15M1035379.
ieee: F. Brunner, J. L. Fischer, and P. Knabner, “Analysis of a modified second-order
mixed hybrid BDM1 finite element method for transport problems in divergence form,”
SIAM Journal on Numerical Analysis, vol. 54, no. 4. Society for Industrial
and Applied Mathematics , pp. 2359–2378, 2016.
ista: Brunner F, Fischer JL, Knabner P. 2016. Analysis of a modified second-order
mixed hybrid BDM1 finite element method for transport problems in divergence form.
SIAM Journal on Numerical Analysis. 54(4), 2359–2378.
mla: Brunner, Fabian, et al. “Analysis of a Modified Second-Order Mixed Hybrid BDM1
Finite Element Method for Transport Problems in Divergence Form.” SIAM Journal
on Numerical Analysis, vol. 54, no. 4, Society for Industrial and Applied
Mathematics , 2016, pp. 2359–78, doi:10.1137/15M1035379.
short: F. Brunner, J.L. Fischer, P. Knabner, SIAM Journal on Numerical Analysis
54 (2016) 2359–2378.
date_created: 2018-12-11T11:51:19Z
date_published: 2016-01-01T00:00:00Z
date_updated: 2021-01-12T06:49:49Z
day: '01'
doi: 10.1137/15M1035379
extern: 1
intvolume: ' 54'
issue: '4'
month: '01'
page: 2359 - 2378
publication: SIAM Journal on Numerical Analysis
publication_status: published
publisher: 'Society for Industrial and Applied Mathematics '
publist_id: '5954'
quality_controlled: 0
status: public
title: Analysis of a modified second-order mixed hybrid BDM1 finite element method
for transport problems in divergence form
type: journal_article
volume: 54
year: '2016'
...
---
_id: '1317'
abstract:
- lang: eng
text: We analyze the behaviour of free boundaries in thin-film flow in the regime
of strong slippage n∈[1,2) and in the regime of very weak slippage n∈,3) qualitatively
and quantitatively. In the regime of strong slippage, we construct initial data
which are bounded from above by the steady state but for which nevertheless instantaneous
forward motion of the free boundary occurs. This shows that the initial behaviour
of the free boundary is not determined just by the growth of the initial data
at the free boundary. Note that this is a new phenomenon for degenerate parabolic
equations which is specific for higher-order equations. Furthermore, this result
resolves a controversy in the literature over optimality of sufficient conditions
for the occurrence of a waiting time phenomenon. In contrast, in the regime of
very weak slippage we derive lower bounds on free boundary propagation which are
optimal in the sense that they coincide up to a constant factor with the known
upper bounds. In particular, in this regime the growth of the initial data at
the free boundary fully determines the initial behaviour of the interface.
acknowledgement: This research was partly supported by the Lithuanian–Swiss cooperation
program under the project agreement No. CH-SMM-01/0.
author:
- first_name: Julian L
full_name: Julian Fischer
id: 2C12A0B0-F248-11E8-B48F-1D18A9856A87
last_name: Fischer
orcid: 0000-0002-0479-558X
citation:
ama: 'Fischer JL. Behaviour of free boundaries in thin-film flow: The regime of
strong slippage and the regime of very weak slippage. Annales de l’Institut
Henri Poincare (C) Non Linear Analysis. 2016;33(5):1301-1327. doi:10.1016/j.anihpc.2015.05.001'
apa: 'Fischer, J. L. (2016). Behaviour of free boundaries in thin-film flow: The
regime of strong slippage and the regime of very weak slippage. Annales de
l’Institut Henri Poincare (C) Non Linear Analysis. Elsevier. https://doi.org/10.1016/j.anihpc.2015.05.001'
chicago: 'Fischer, Julian L. “Behaviour of Free Boundaries in Thin-Film Flow: The
Regime of Strong Slippage and the Regime of Very Weak Slippage.” Annales de
l’Institut Henri Poincare (C) Non Linear Analysis. Elsevier, 2016. https://doi.org/10.1016/j.anihpc.2015.05.001.'
ieee: 'J. L. Fischer, “Behaviour of free boundaries in thin-film flow: The regime
of strong slippage and the regime of very weak slippage,” Annales de l’Institut
Henri Poincare (C) Non Linear Analysis, vol. 33, no. 5. Elsevier, pp. 1301–1327,
2016.'
ista: 'Fischer JL. 2016. Behaviour of free boundaries in thin-film flow: The regime
of strong slippage and the regime of very weak slippage. Annales de l’Institut
Henri Poincare (C) Non Linear Analysis. 33(5), 1301–1327.'
mla: 'Fischer, Julian L. “Behaviour of Free Boundaries in Thin-Film Flow: The Regime
of Strong Slippage and the Regime of Very Weak Slippage.” Annales de l’Institut
Henri Poincare (C) Non Linear Analysis, vol. 33, no. 5, Elsevier, 2016, pp.
1301–27, doi:10.1016/j.anihpc.2015.05.001.'
short: J.L. Fischer, Annales de l’Institut Henri Poincare (C) Non Linear Analysis
33 (2016) 1301–1327.
date_created: 2018-12-11T11:51:20Z
date_published: 2016-09-01T00:00:00Z
date_updated: 2021-01-12T06:49:50Z
day: '01'
doi: 10.1016/j.anihpc.2015.05.001
extern: 1
intvolume: ' 33'
issue: '5'
month: '09'
page: 1301 - 1327
publication: Annales de l'Institut Henri Poincare (C) Non Linear Analysis
publication_status: published
publisher: Elsevier
publist_id: '5952'
quality_controlled: 0
status: public
title: 'Behaviour of free boundaries in thin-film flow: The regime of strong slippage
and the regime of very weak slippage'
type: journal_article
volume: 33
year: '2016'
...
---
_id: '1318'
abstract:
- lang: eng
text: 'We develop a large-scale regularity theory of higher order for divergence-form
elliptic equations with heterogeneous coefficient fields a in the context of stochastic
homogenization. The large-scale regularity of a-harmonic functions is encoded
by Liouville principles: The space of a-harmonic functions that grow at most like
a polynomial of degree k has the same dimension as in the constant-coefficient
case. This result can be seen as the qualitative side of a large-scale Ck,α-regularity
theory, which in the present work is developed in the form of a corresponding
Ck,α-“excess decay” estimate: For a given a-harmonic function u on a ball BR,
its energy distance on some ball Br to the above space of a-harmonic functions
that grow at most like a polynomial of degree k has the natural decay in the radius
r above some minimal radius r0. Though motivated by stochastic homogenization,
the contribution of this paper is of purely deterministic nature: We work under
the assumption that for the given realization a of the coefficient field, the
couple (φ, σ) of scalar and vector potentials of the harmonic coordinates, where
φ is the usual corrector, grows sublinearly in a mildly quantified way. We then
construct “kth-order correctors” and thereby the space of a-harmonic functions
that grow at most like a polynomial of degree k, establish the above excess decay,
and then the corresponding Liouville principle.'
author:
- first_name: Julian L
full_name: Julian Fischer
id: 2C12A0B0-F248-11E8-B48F-1D18A9856A87
last_name: Fischer
orcid: 0000-0002-0479-558X
- first_name: Felix
full_name: Otto, Felix
last_name: Otto
citation:
ama: Fischer JL, Otto F. A higher-order large scale regularity theory for random
elliptic operators. Communications in Partial Differential Equations. 2016;41(7):1108-1148.
doi:10.1080/03605302.2016.1179318
apa: Fischer, J. L., & Otto, F. (2016). A higher-order large scale regularity
theory for random elliptic operators. Communications in Partial Differential
Equations. Taylor & Francis. https://doi.org/10.1080/03605302.2016.1179318
chicago: Fischer, Julian L, and Felix Otto. “A Higher-Order Large Scale Regularity
Theory for Random Elliptic Operators.” Communications in Partial Differential
Equations. Taylor & Francis, 2016. https://doi.org/10.1080/03605302.2016.1179318.
ieee: J. L. Fischer and F. Otto, “A higher-order large scale regularity theory for
random elliptic operators,” Communications in Partial Differential Equations,
vol. 41, no. 7. Taylor & Francis, pp. 1108–1148, 2016.
ista: Fischer JL, Otto F. 2016. A higher-order large scale regularity theory for
random elliptic operators. Communications in Partial Differential Equations. 41(7),
1108–1148.
mla: Fischer, Julian L., and Felix Otto. “A Higher-Order Large Scale Regularity
Theory for Random Elliptic Operators.” Communications in Partial Differential
Equations, vol. 41, no. 7, Taylor & Francis, 2016, pp. 1108–48, doi:10.1080/03605302.2016.1179318.
short: J.L. Fischer, F. Otto, Communications in Partial Differential Equations 41
(2016) 1108–1148.
date_created: 2018-12-11T11:51:20Z
date_published: 2016-07-02T00:00:00Z
date_updated: 2021-01-12T06:49:50Z
day: '02'
doi: 10.1080/03605302.2016.1179318
extern: 1
intvolume: ' 41'
issue: '7'
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1503.07578
month: '07'
oa: 1
page: 1108 - 1148
publication: Communications in Partial Differential Equations
publication_status: published
publisher: Taylor & Francis
publist_id: '5953'
quality_controlled: 0
status: public
title: A higher-order large scale regularity theory for random elliptic operators
type: journal_article
volume: 41
year: '2016'
...
---
_id: '1319'
abstract:
- lang: eng
text: We present a novel optimization-based algorithm for the design and fabrication
of customized, deformable input devices, capable of continuously sensing their
deformation. We propose to embed piezoresistive sensing elements into flexible
3D printed objects. These sensing elements are then utilized to recover rich and
natural user interactions at runtime. Designing such objects is a challenging
and hard problem if attempted manually for all but the simplest geometries and
deformations. Our method simultaneously optimizes the internal routing of the
sensing elements and computes a mapping from low-level sensor readings to user-specified
outputs in order to minimize reconstruction error. We demonstrate the power and
flexibility of the approach by designing and fabricating a set of flexible input
devices. Our results indicate that the optimization-based design greatly outperforms
manual routings in terms of reconstruction accuracy and thus interaction fidelity.
acknowledgement: "We thank Damian Karrer, Rocco Ghielmini and Jemin\r\nHwangbo
for their help in our initial explorations. We would\r\nlike to thank Christian
Schumacher for creating the video and\r\nC\r\n ́\r\necile Edwards-Rietmann for providing
the voiceover. Mau-\r\nrizio Nitti helped us in designing our 3D characters. We
thank\r\nChiara Daraio for insightful discussions on material proper-\r\nties and
3D printing. We also thank the CHI reviewers for\r\ntheir feedback and guidance.
Fabrizio Pece was supported by\r\nan ETH/Marie Curie fellowship (FEL-3314-1)."
author:
- first_name: Moritz
full_name: Bächer, Moritz
last_name: Bächer
- first_name: Benjamin
full_name: Hepp, Benjamin
last_name: Hepp
- first_name: Fabrizio
full_name: Pece, Fabrizio
last_name: Pece
- first_name: Paul
full_name: Kry, Paul
last_name: Kry
- first_name: Bernd
full_name: Bickel, Bernd
id: 49876194-F248-11E8-B48F-1D18A9856A87
last_name: Bickel
orcid: 0000-0001-6511-9385
- first_name: Bernhard
full_name: Thomaszewski, Bernhard
last_name: Thomaszewski
- first_name: Otmar
full_name: Hilliges, Otmar
last_name: Hilliges
citation:
ama: 'Bächer M, Hepp B, Pece F, et al. DefSense: computational design of customized
deformable input devices. In: ACM; 2016:3806-3816. doi:10.1145/2858036.2858354'
apa: 'Bächer, M., Hepp, B., Pece, F., Kry, P., Bickel, B., Thomaszewski, B., &
Hilliges, O. (2016). DefSense: computational design of customized deformable input
devices (pp. 3806–3816). Presented at the CHI: Conference on Human Factors in
Computing Systems, San Jose, California, USA: ACM. https://doi.org/10.1145/2858036.2858354'
chicago: 'Bächer, Moritz, Benjamin Hepp, Fabrizio Pece, Paul Kry, Bernd Bickel,
Bernhard Thomaszewski, and Otmar Hilliges. “DefSense: Computational Design of
Customized Deformable Input Devices,” 3806–16. ACM, 2016. https://doi.org/10.1145/2858036.2858354.'
ieee: 'M. Bächer et al., “DefSense: computational design of customized deformable
input devices,” presented at the CHI: Conference on Human Factors in Computing
Systems, San Jose, California, USA, 2016, pp. 3806–3816.'
ista: 'Bächer M, Hepp B, Pece F, Kry P, Bickel B, Thomaszewski B, Hilliges O. 2016.
DefSense: computational design of customized deformable input devices. CHI: Conference
on Human Factors in Computing Systems, 3806–3816.'
mla: 'Bächer, Moritz, et al. DefSense: Computational Design of Customized Deformable
Input Devices. ACM, 2016, pp. 3806–16, doi:10.1145/2858036.2858354.'
short: M. Bächer, B. Hepp, F. Pece, P. Kry, B. Bickel, B. Thomaszewski, O. Hilliges,
in:, ACM, 2016, pp. 3806–3816.
conference:
end_date: 2016-05-12
location: San Jose, California, USA
name: 'CHI: Conference on Human Factors in Computing Systems'
start_date: 2016-05-07
date_created: 2018-12-11T11:51:21Z
date_published: 2016-05-07T00:00:00Z
date_updated: 2021-01-12T06:49:51Z
day: '07'
department:
- _id: BeBi
doi: 10.1145/2858036.2858354
language:
- iso: eng
month: '05'
oa_version: None
page: 3806 - 3816
publication_status: published
publisher: ACM
publist_id: '5951'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'DefSense: computational design of customized deformable input devices'
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
year: '2016'
...
---
_id: '1320'
abstract:
- lang: eng
text: 'In recent years, several biomolecular systems have been shown to be scale-invariant
(SI), i.e. to show the same output dynamics when exposed to geometrically scaled
input signals (u → pu, p > 0) after pre-adaptation to accordingly scaled constant
inputs. In this article, we show that SI systems-as well as systems invariant
with respect to other input transformations-can realize nonlinear differential
operators: when excited by inputs obeying functional forms characteristic for
a given class of invariant systems, the systems'' outputs converge to constant
values directly quantifying the speed of the input.'
acknowledgement: The research leading to these results has received funding from the
People Programme (Marie Curie Actions) of the European Union's Seventh Framework
Programme (FP7/2007-2013) under REA grant agreement n° [291734]. Work supported
in part by grants AFOSR FA9550-14-1-0060 and NIH 1R01GM100473.
article_number: '7526722'
author:
- first_name: Moritz
full_name: Lang, Moritz
id: 29E0800A-F248-11E8-B48F-1D18A9856A87
last_name: Lang
- first_name: Eduardo
full_name: Sontag, Eduardo
last_name: Sontag
citation:
ama: 'Lang M, Sontag E. Scale-invariant systems realize nonlinear differential operators.
In: Vol 2016-July. IEEE; 2016. doi:10.1109/ACC.2016.7526722'
apa: 'Lang, M., & Sontag, E. (2016). Scale-invariant systems realize nonlinear
differential operators (Vol. 2016–July). Presented at the ACC: American Control
Conference, Boston, MA, USA: IEEE. https://doi.org/10.1109/ACC.2016.7526722'
chicago: Lang, Moritz, and Eduardo Sontag. “Scale-Invariant Systems Realize Nonlinear
Differential Operators,” Vol. 2016–July. IEEE, 2016. https://doi.org/10.1109/ACC.2016.7526722.
ieee: 'M. Lang and E. Sontag, “Scale-invariant systems realize nonlinear differential
operators,” presented at the ACC: American Control Conference, Boston, MA, USA,
2016, vol. 2016–July.'
ista: 'Lang M, Sontag E. 2016. Scale-invariant systems realize nonlinear differential
operators. ACC: American Control Conference vol. 2016–July, 7526722.'
mla: Lang, Moritz, and Eduardo Sontag. Scale-Invariant Systems Realize Nonlinear
Differential Operators. Vol. 2016–July, 7526722, IEEE, 2016, doi:10.1109/ACC.2016.7526722.
short: M. Lang, E. Sontag, in:, IEEE, 2016.
conference:
end_date: 2016-07-08
location: Boston, MA, USA
name: 'ACC: American Control Conference'
start_date: 2016-07-06
date_created: 2018-12-11T11:51:21Z
date_published: 2016-07-28T00:00:00Z
date_updated: 2021-01-12T06:49:51Z
day: '28'
ddc:
- '003'
- '621'
department:
- _id: CaGu
- _id: GaTk
doi: 10.1109/ACC.2016.7526722
ec_funded: 1
file:
- access_level: local
checksum: 7219432b43defc62a0d45f48d4ce6a19
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:16:17Z
date_updated: 2020-07-14T12:44:43Z
file_id: '5203'
file_name: IST-2017-810-v1+1_root.pdf
file_size: 539166
relation: main_file
file_date_updated: 2020-07-14T12:44:43Z
has_accepted_license: '1'
language:
- iso: eng
month: '07'
oa_version: Preprint
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication_status: published
publisher: IEEE
publist_id: '5950'
pubrep_id: '810'
quality_controlled: '1'
scopus_import: 1
status: public
title: Scale-invariant systems realize nonlinear differential operators
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 2016-July
year: '2016'
...
---
_id: '1321'
abstract:
- lang: eng
text: Most migrating cells extrude their front by the force of actin polymerization.
Polymerization requires an initial nucleation step, which is mediated by factors
establishing either parallel filaments in the case of filopodia or branched filaments
that form the branched lamellipodial network. Branches are considered essential
for regular cell motility and are initiated by the Arp2/3 complex, which in turn
is activated by nucleation-promoting factors of the WASP and WAVE families. Here
we employed rapid amoeboid crawling leukocytes and found that deletion of the
WAVE complex eliminated actin branching and thus lamellipodia formation. The cells
were left with parallel filaments at the leading edge, which translated, depending
on the differentiation status of the cell, into a unipolar pointed cell shape
or cells with multiple filopodia. Remarkably, unipolar cells migrated with increased
speed and enormous directional persistence, while they were unable to turn towards
chemotactic gradients. Cells with multiple filopodia retained chemotactic activity
but their migration was progressively impaired with increasing geometrical complexity
of the extracellular environment. These findings establish that diversified leading
edge protrusions serve as explorative structures while they slow down actual locomotion.
acknowledged_ssus:
- _id: SSU
acknowledgement: "This work was supported by the German Research Foundation (DFG)
Priority Program SP 1464 to T.E.B.S. and M.S., and European Research Council (ERC
GA 281556) and Human Frontiers Program grants to M.S.\r\nService Units of IST Austria
for excellent technical support."
article_processing_charge: No
article_type: original
author:
- first_name: Alexander F
full_name: Leithner, Alexander F
id: 3B1B77E4-F248-11E8-B48F-1D18A9856A87
last_name: Leithner
orcid: 0000-0002-1073-744X
- first_name: Alexander
full_name: Eichner, Alexander
id: 4DFA52AE-F248-11E8-B48F-1D18A9856A87
last_name: Eichner
- first_name: Jan
full_name: Müller, Jan
id: AD07FDB4-0F61-11EA-8158-C4CC64CEAA8D
last_name: Müller
- first_name: Anne
full_name: Reversat, Anne
id: 35B76592-F248-11E8-B48F-1D18A9856A87
last_name: Reversat
orcid: 0000-0003-0666-8928
- first_name: Markus
full_name: Brown, Markus
id: 3DAB9AFC-F248-11E8-B48F-1D18A9856A87
last_name: Brown
- first_name: Jan
full_name: Schwarz, Jan
id: 346C1EC6-F248-11E8-B48F-1D18A9856A87
last_name: Schwarz
- first_name: Jack
full_name: Merrin, Jack
id: 4515C308-F248-11E8-B48F-1D18A9856A87
last_name: Merrin
orcid: 0000-0001-5145-4609
- first_name: David
full_name: De Gorter, David
last_name: De Gorter
- first_name: Florian
full_name: Schur, Florian
id: 48AD8942-F248-11E8-B48F-1D18A9856A87
last_name: Schur
orcid: 0000-0003-4790-8078
- first_name: Jonathan
full_name: Bayerl, Jonathan
last_name: Bayerl
- first_name: Ingrid
full_name: De Vries, Ingrid
id: 4C7D837E-F248-11E8-B48F-1D18A9856A87
last_name: De Vries
- first_name: Stefan
full_name: Wieser, Stefan
id: 355AA5A0-F248-11E8-B48F-1D18A9856A87
last_name: Wieser
orcid: 0000-0002-2670-2217
- first_name: Robert
full_name: Hauschild, Robert
id: 4E01D6B4-F248-11E8-B48F-1D18A9856A87
last_name: Hauschild
orcid: 0000-0001-9843-3522
- first_name: Frank
full_name: Lai, Frank
last_name: Lai
- first_name: Markus
full_name: Moser, Markus
last_name: Moser
- first_name: Dontscho
full_name: Kerjaschki, Dontscho
last_name: Kerjaschki
- first_name: Klemens
full_name: Rottner, Klemens
last_name: Rottner
- first_name: Victor
full_name: Small, Victor
last_name: Small
- first_name: Theresia
full_name: Stradal, Theresia
last_name: Stradal
- first_name: Michael K
full_name: Sixt, Michael K
id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
last_name: Sixt
orcid: 0000-0002-6620-9179
citation:
ama: Leithner AF, Eichner A, Müller J, et al. Diversified actin protrusions promote
environmental exploration but are dispensable for locomotion of leukocytes. Nature
Cell Biology. 2016;18:1253-1259. doi:10.1038/ncb3426
apa: Leithner, A. F., Eichner, A., Müller, J., Reversat, A., Brown, M., Schwarz,
J., … Sixt, M. K. (2016). Diversified actin protrusions promote environmental
exploration but are dispensable for locomotion of leukocytes. Nature Cell Biology.
Nature Publishing Group. https://doi.org/10.1038/ncb3426
chicago: Leithner, Alexander F, Alexander Eichner, Jan Müller, Anne Reversat, Markus
Brown, Jan Schwarz, Jack Merrin, et al. “Diversified Actin Protrusions Promote
Environmental Exploration but Are Dispensable for Locomotion of Leukocytes.” Nature
Cell Biology. Nature Publishing Group, 2016. https://doi.org/10.1038/ncb3426.
ieee: A. F. Leithner et al., “Diversified actin protrusions promote environmental
exploration but are dispensable for locomotion of leukocytes,” Nature Cell
Biology, vol. 18. Nature Publishing Group, pp. 1253–1259, 2016.
ista: Leithner AF, Eichner A, Müller J, Reversat A, Brown M, Schwarz J, Merrin J,
De Gorter D, Schur FK, Bayerl J, de Vries I, Wieser S, Hauschild R, Lai F, Moser
M, Kerjaschki D, Rottner K, Small V, Stradal T, Sixt MK. 2016. Diversified actin
protrusions promote environmental exploration but are dispensable for locomotion
of leukocytes. Nature Cell Biology. 18, 1253–1259.
mla: Leithner, Alexander F., et al. “Diversified Actin Protrusions Promote Environmental
Exploration but Are Dispensable for Locomotion of Leukocytes.” Nature Cell
Biology, vol. 18, Nature Publishing Group, 2016, pp. 1253–59, doi:10.1038/ncb3426.
short: A.F. Leithner, A. Eichner, J. Müller, A. Reversat, M. Brown, J. Schwarz,
J. Merrin, D. De Gorter, F.K. Schur, J. Bayerl, I. de Vries, S. Wieser, R. Hauschild,
F. Lai, M. Moser, D. Kerjaschki, K. Rottner, V. Small, T. Stradal, M.K. Sixt,
Nature Cell Biology 18 (2016) 1253–1259.
date_created: 2018-12-11T11:51:21Z
date_published: 2016-10-24T00:00:00Z
date_updated: 2024-03-25T23:30:09Z
day: '24'
ddc:
- '570'
department:
- _id: MiSi
- _id: NanoFab
- _id: Bio
doi: 10.1038/ncb3426
ec_funded: 1
file:
- access_level: open_access
checksum: e1411cb7c99a2d9089c178a6abef25e7
content_type: application/pdf
creator: dernst
date_created: 2020-05-14T16:33:46Z
date_updated: 2020-07-14T12:44:43Z
file_id: '7844'
file_name: 2018_NatureCell_Leithner.pdf
file_size: 4433280
relation: main_file
file_date_updated: 2020-07-14T12:44:43Z
has_accepted_license: '1'
intvolume: ' 18'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-sa/4.0/
month: '10'
oa: 1
oa_version: Submitted Version
page: 1253 - 1259
project:
- _id: 25A603A2-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '281556'
name: Cytoskeletal force generation and force transduction of migrating leukocytes
(EU)
publication: Nature Cell Biology
publication_status: published
publisher: Nature Publishing Group
publist_id: '5949'
quality_controlled: '1'
related_material:
record:
- id: '323'
relation: dissertation_contains
status: public
scopus_import: 1
status: public
title: Diversified actin protrusions promote environmental exploration but are dispensable
for locomotion of leukocytes
tmp:
image: /images/cc_by_nc_sa.png
legal_code_url: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC
BY-NC-SA 4.0)
short: CC BY-NC-SA (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 18
year: '2016'
...
---
_id: '1322'
abstract:
- lang: eng
text: Direct reciprocity is a major mechanism for the evolution of cooperation.
Several classical studies have suggested that humans should quickly learn to adopt
reciprocal strategies to establish mutual cooperation in repeated interactions.
On the other hand, the recently discovered theory of ZD strategies has found that
subjects who use extortionate strategies are able to exploit and subdue cooperators.
Although such extortioners have been predicted to succeed in any population of
adaptive opponents, theoretical follow-up studies questioned whether extortion
can evolve in reality. However, most of these studies presumed that individuals
have similar strategic possibilities and comparable outside options, whereas asymmetries
are ubiquitous in real world applications. Here we show with a model and an economic
experiment that extortionate strategies readily emerge once subjects differ in
their strategic power. Our experiment combines a repeated social dilemma with
asymmetric partner choice. In our main treatment there is one randomly chosen
group member who is unilaterally allowed to exchange one of the other group members
after every ten rounds of the social dilemma. We find that this asymmetric replacement
opportunity generally promotes cooperation, but often the resulting payoff distribution
reflects the underlying power structure. Almost half of the subjects in a better
strategic position turn into extortioners, who quickly proceed to exploit their
peers. By adapting their cooperation probabilities consistent with ZD theory,
extortioners force their co-players to cooperate without being similarly cooperative
themselves. Comparison to non-extortionate players under the same conditions indicates
a substantial net gain to extortion. Our results thus highlight how power asymmetries
can endanger mutually beneficial interactions, and transform them into exploitative
relationships. In particular, our results indicate that the extortionate strategies
predicted from ZD theory could play a more prominent role in our daily interactions
than previously thought.
acknowledgement: 'CH was funded by the Schrödinger program of the Austrian Science
Fund (FWF) J3475. '
article_number: e0163867
author:
- first_name: Christian
full_name: Hilbe, Christian
id: 2FDF8F3C-F248-11E8-B48F-1D18A9856A87
last_name: Hilbe
orcid: 0000-0001-5116-955X
- first_name: Kristin
full_name: Hagel, Kristin
last_name: Hagel
- first_name: Manfred
full_name: Milinski, Manfred
last_name: Milinski
citation:
ama: Hilbe C, Hagel K, Milinski M. Asymmetric power boosts extortion in an economic
experiment. PLoS One. 2016;11(10). doi:10.1371/journal.pone.0163867
apa: Hilbe, C., Hagel, K., & Milinski, M. (2016). Asymmetric power boosts extortion
in an economic experiment. PLoS One. Public Library of Science. https://doi.org/10.1371/journal.pone.0163867
chicago: Hilbe, Christian, Kristin Hagel, and Manfred Milinski. “Asymmetric Power
Boosts Extortion in an Economic Experiment.” PLoS One. Public Library of
Science, 2016. https://doi.org/10.1371/journal.pone.0163867.
ieee: C. Hilbe, K. Hagel, and M. Milinski, “Asymmetric power boosts extortion in
an economic experiment,” PLoS One, vol. 11, no. 10. Public Library of Science,
2016.
ista: Hilbe C, Hagel K, Milinski M. 2016. Asymmetric power boosts extortion in an
economic experiment. PLoS One. 11(10), e0163867.
mla: Hilbe, Christian, et al. “Asymmetric Power Boosts Extortion in an Economic
Experiment.” PLoS One, vol. 11, no. 10, e0163867, Public Library of Science,
2016, doi:10.1371/journal.pone.0163867.
short: C. Hilbe, K. Hagel, M. Milinski, PLoS One 11 (2016).
date_created: 2018-12-11T11:51:22Z
date_published: 2016-10-04T00:00:00Z
date_updated: 2023-02-23T14:11:27Z
day: '04'
ddc:
- '004'
- '006'
department:
- _id: KrCh
doi: 10.1371/journal.pone.0163867
file:
- access_level: open_access
checksum: 6b33e394003dfe8b4ca6be1858aaa8e3
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:08:08Z
date_updated: 2020-07-14T12:44:44Z
file_id: '4668'
file_name: IST-2016-716-v1+1_journal.pone.0163867.PDF
file_size: 2077905
relation: main_file
file_date_updated: 2020-07-14T12:44:44Z
has_accepted_license: '1'
intvolume: ' 11'
issue: '10'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
publication: PLoS One
publication_status: published
publisher: Public Library of Science
publist_id: '5948'
pubrep_id: '716'
quality_controlled: '1'
related_material:
record:
- id: '9867'
relation: research_data
status: public
- id: '9868'
relation: research_data
status: public
scopus_import: 1
status: public
title: Asymmetric power boosts extortion in an economic experiment
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 11
year: '2016'
...
---
_id: '1323'
abstract:
- lang: eng
text: Mossy fiber synapses on CA3 pyramidal cells are 'conditional detonators' that
reliably discharge postsynaptic targets. The 'conditional' nature implies that
burst activity in dentate gyrus granule cells is required for detonation. Whether
single unitary excitatory postsynaptic potentials (EPSPs) trigger spikes in CA3
neurons remains unknown. Mossy fiber synapses exhibit both pronounced short-term
facilitation and uniquely large post-tetanic potentiation (PTP). We tested whether
PTP could convert mossy fiber synapses from subdetonator into detonator mode,
using a recently developed method to selectively and noninvasively stimulate individual
presynaptic terminals in rat brain slices. Unitary EPSPs failed to initiate a
spike in CA3 neurons under control conditions, but reliably discharged them after
induction of presynaptic short-term plasticity. Remarkably, PTP switched mossy
fiber synapses into full detonators for tens of seconds. Plasticity-dependent
detonation may be critical for efficient coding, storage, and recall of information
in the granule cell–CA3 cell network.
acknowledged_ssus:
- _id: M-Shop
- _id: PreCl
article_number: e17977
author:
- first_name: Nicholas
full_name: Vyleta, Nicholas
id: 36C4978E-F248-11E8-B48F-1D18A9856A87
last_name: Vyleta
- first_name: Carolina
full_name: Borges Merjane, Carolina
id: 4305C450-F248-11E8-B48F-1D18A9856A87
last_name: Borges Merjane
orcid: 0000-0003-0005-401X
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Vyleta N, Borges Merjane C, Jonas PM. Plasticity-dependent, full detonation
at hippocampal mossy fiber–CA3 pyramidal neuron synapses. eLife. 2016;5.
doi:10.7554/eLife.17977
apa: Vyleta, N., Borges Merjane, C., & Jonas, P. M. (2016). Plasticity-dependent,
full detonation at hippocampal mossy fiber–CA3 pyramidal neuron synapses. ELife.
eLife Sciences Publications. https://doi.org/10.7554/eLife.17977
chicago: Vyleta, Nicholas, Carolina Borges Merjane, and Peter M Jonas. “Plasticity-Dependent,
Full Detonation at Hippocampal Mossy Fiber–CA3 Pyramidal Neuron Synapses.” ELife.
eLife Sciences Publications, 2016. https://doi.org/10.7554/eLife.17977.
ieee: N. Vyleta, C. Borges Merjane, and P. M. Jonas, “Plasticity-dependent, full
detonation at hippocampal mossy fiber–CA3 pyramidal neuron synapses,” eLife,
vol. 5. eLife Sciences Publications, 2016.
ista: Vyleta N, Borges Merjane C, Jonas PM. 2016. Plasticity-dependent, full detonation
at hippocampal mossy fiber–CA3 pyramidal neuron synapses. eLife. 5, e17977.
mla: Vyleta, Nicholas, et al. “Plasticity-Dependent, Full Detonation at Hippocampal
Mossy Fiber–CA3 Pyramidal Neuron Synapses.” ELife, vol. 5, e17977, eLife
Sciences Publications, 2016, doi:10.7554/eLife.17977.
short: N. Vyleta, C. Borges Merjane, P.M. Jonas, ELife 5 (2016).
date_created: 2018-12-11T11:51:22Z
date_published: 2016-10-25T00:00:00Z
date_updated: 2023-02-21T10:34:24Z
day: '25'
ddc:
- '571'
- '572'
department:
- _id: PeJo
doi: 10.7554/eLife.17977
ec_funded: 1
file:
- access_level: open_access
checksum: a7201280c571bed88ebd459ce5ce6a47
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:17:05Z
date_updated: 2020-07-14T12:44:44Z
file_id: '5257'
file_name: IST-2016-715-v1+1_e17977-download.pdf
file_size: 1477891
relation: main_file
file_date_updated: 2020-07-14T12:44:44Z
has_accepted_license: '1'
intvolume: ' 5'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
project:
- _id: 25C0F108-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '268548'
name: Nanophysiology of fast-spiking, parvalbumin-expressing GABAergic interneurons
- _id: 25B7EB9E-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '692692'
name: Biophysics and circuit function of a giant cortical glumatergic synapse
publication: eLife
publication_status: published
publisher: eLife Sciences Publications
publist_id: '5947'
pubrep_id: '715'
quality_controlled: '1'
scopus_import: 1
status: public
title: Plasticity-dependent, full detonation at hippocampal mossy fiber–CA3 pyramidal
neuron synapses
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2016'
...
---
_id: '1324'
abstract:
- lang: eng
text: 'DEC-POMDPs extend POMDPs to a multi-agent setting, where several agents operate
in an uncertain environment independently to achieve a joint objective. DEC-POMDPs
have been studied with finite-horizon and infinite-horizon discounted-sum objectives,
and there exist solvers both for exact and approximate solutions. In this work
we consider Goal-DEC-POMDPs, where given a set of target states, the objective
is to ensure that the target set is reached with minimal cost. We consider the
indefinite-horizon (infinite-horizon with either discounted-sum, or undiscounted-sum,
where absorbing goal states have zero-cost) problem. We present a new and novel
method to solve the problem that extends methods for finite-horizon DEC-POMDPs
and the RTDP-Bel approach for POMDPs. We present experimental results on several
examples, and show that our approach presents promising results. Copyright '
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Martin
full_name: Chmelik, Martin
id: 3624234E-F248-11E8-B48F-1D18A9856A87
last_name: Chmelik
citation:
ama: 'Chatterjee K, Chmelik M. Indefinite-horizon reachability in Goal-DEC-POMDPs.
In: Proceedings of the Twenty-Sixth International Conference on International
Conference on Automated Planning and Scheduling. Vol 2016-January. AAAI Press;
2016:88-96.'
apa: 'Chatterjee, K., & Chmelik, M. (2016). Indefinite-horizon reachability
in Goal-DEC-POMDPs. In Proceedings of the Twenty-Sixth International Conference
on International Conference on Automated Planning and Scheduling (Vol. 2016–January,
pp. 88–96). London, United Kingdom: AAAI Press.'
chicago: Chatterjee, Krishnendu, and Martin Chmelik. “Indefinite-Horizon Reachability
in Goal-DEC-POMDPs.” In Proceedings of the Twenty-Sixth International Conference
on International Conference on Automated Planning and Scheduling, 2016–January:88–96.
AAAI Press, 2016.
ieee: K. Chatterjee and M. Chmelik, “Indefinite-horizon reachability in Goal-DEC-POMDPs,”
in Proceedings of the Twenty-Sixth International Conference on International
Conference on Automated Planning and Scheduling, London, United Kingdom, 2016,
vol. 2016–January, pp. 88–96.
ista: 'Chatterjee K, Chmelik M. 2016. Indefinite-horizon reachability in Goal-DEC-POMDPs.
Proceedings of the Twenty-Sixth International Conference on International Conference
on Automated Planning and Scheduling. ICAPS: International Conference on Automated
Planning and Scheduling vol. 2016–January, 88–96.'
mla: Chatterjee, Krishnendu, and Martin Chmelik. “Indefinite-Horizon Reachability
in Goal-DEC-POMDPs.” Proceedings of the Twenty-Sixth International Conference
on International Conference on Automated Planning and Scheduling, vol. 2016–January,
AAAI Press, 2016, pp. 88–96.
short: K. Chatterjee, M. Chmelik, in:, Proceedings of the Twenty-Sixth International
Conference on International Conference on Automated Planning and Scheduling, AAAI
Press, 2016, pp. 88–96.
conference:
end_date: 2016-06-17
location: London, United Kingdom
name: 'ICAPS: International Conference on Automated Planning and Scheduling'
start_date: 2016-06-12
date_created: 2018-12-11T11:51:22Z
date_published: 2016-01-01T00:00:00Z
date_updated: 2021-01-12T06:49:53Z
day: '01'
department:
- _id: KrCh
ec_funded: 1
language:
- iso: eng
main_file_link:
- url: http://www.aaai.org/ocs/index.php/ICAPS/ICAPS16/paper/view/12999
month: '01'
oa_version: None
page: 88 - 96
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
publication: Proceedings of the Twenty-Sixth International Conference on International
Conference on Automated Planning and Scheduling
publication_status: published
publisher: AAAI Press
publist_id: '5946'
quality_controlled: '1'
scopus_import: 1
status: public
title: Indefinite-horizon reachability in Goal-DEC-POMDPs
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 2016-January
year: '2016'
...
---
_id: '1325'
abstract:
- lang: eng
text: We study graphs and two-player games in which rewards are assigned to states,
and the goal of the players is to satisfy or dissatisfy certain property of the
generated outcome, given as a mean payoff property. Since the notion of mean-payoff
does not reflect possible fluctuations from the mean-payoff along a run, we propose
definitions and algorithms for capturing the stability of the system, and give
algorithms for deciding if a given mean payoff and stability objective can be
ensured in the system.
acknowledgement: "The work has been supported by the Czech Science Foundation, grant
No. 15-17564S, by EPSRC grant\r\nEP/M023656/1, and by the People Programme (Marie
Curie Actions) of the European Union’s Seventh\r\nFramework Programme (FP7/2007-2013)
under REA grant agreement no [291734]"
alternative_title:
- LIPIcs
article_number: '10'
author:
- first_name: Tomáš
full_name: Brázdil, Tomáš
last_name: Brázdil
- first_name: Vojtěch
full_name: Forejt, Vojtěch
last_name: Forejt
- first_name: Antonín
full_name: Kučera, Antonín
last_name: Kučera
- first_name: Petr
full_name: Novotny, Petr
id: 3CC3B868-F248-11E8-B48F-1D18A9856A87
last_name: Novotny
citation:
ama: 'Brázdil T, Forejt V, Kučera A, Novotný P. Stability in graphs and games. In:
Vol 59. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2016. doi:10.4230/LIPIcs.CONCUR.2016.10'
apa: 'Brázdil, T., Forejt, V., Kučera, A., & Novotný, P. (2016). Stability in
graphs and games (Vol. 59). Presented at the CONCUR: Concurrency Theory, Quebec
City, Canada: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. https://doi.org/10.4230/LIPIcs.CONCUR.2016.10'
chicago: Brázdil, Tomáš, Vojtěch Forejt, Antonín Kučera, and Petr Novotný. “Stability
in Graphs and Games,” Vol. 59. Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
2016. https://doi.org/10.4230/LIPIcs.CONCUR.2016.10.
ieee: 'T. Brázdil, V. Forejt, A. Kučera, and P. Novotný, “Stability in graphs and
games,” presented at the CONCUR: Concurrency Theory, Quebec City, Canada, 2016,
vol. 59.'
ista: 'Brázdil T, Forejt V, Kučera A, Novotný P. 2016. Stability in graphs and games.
CONCUR: Concurrency Theory, LIPIcs, vol. 59, 10.'
mla: Brázdil, Tomáš, et al. Stability in Graphs and Games. Vol. 59, 10, Schloss
Dagstuhl - Leibniz-Zentrum für Informatik, 2016, doi:10.4230/LIPIcs.CONCUR.2016.10.
short: T. Brázdil, V. Forejt, A. Kučera, P. Novotný, in:, Schloss Dagstuhl - Leibniz-Zentrum
für Informatik, 2016.
conference:
end_date: 2016-08-26
location: Quebec City, Canada
name: 'CONCUR: Concurrency Theory'
start_date: 2016-08-23
date_created: 2018-12-11T11:51:23Z
date_published: 2016-08-01T00:00:00Z
date_updated: 2021-01-12T06:49:53Z
day: '01'
ddc:
- '004'
department:
- _id: KrCh
doi: 10.4230/LIPIcs.CONCUR.2016.10
ec_funded: 1
file:
- access_level: open_access
checksum: 3c2dc6ab0358f8aa8f7aa7d6c1293159
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:16:40Z
date_updated: 2020-07-14T12:44:44Z
file_id: '5229'
file_name: IST-2016-665-v1+1_Forejt_et_al__Stability_in_graphs_and_games.pdf
file_size: 553648
relation: main_file
file_date_updated: 2020-07-14T12:44:44Z
has_accepted_license: '1'
intvolume: ' 59'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
publist_id: '5944'
pubrep_id: '665'
quality_controlled: '1'
scopus_import: 1
status: public
title: Stability in graphs and games
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 59
year: '2016'
...
---
_id: '1326'
abstract:
- lang: eng
text: 'Energy Markov Decision Processes (EMDPs) are finite-state Markov decision
processes where each transition is assigned an integer counter update and a rational
payoff. An EMDP configuration is a pair s(n), where s is a control state and n
is the current counter value. The configurations are changed by performing transitions
in the standard way. We consider the problem of computing a safe strategy (i.e.,
a strategy that keeps the counter non-negative) which maximizes the expected mean
payoff. '
acknowledgement: The research was funded by the Czech Science Foundation Grant No.
P202/12/G061 and by the People Programme (Marie Curie Actions) of the European Union’s
Seventh Framework Programme (FP7/2007-2013) under REA grant agreement no [291734].
alternative_title:
- LNCS
author:
- first_name: Tomáš
full_name: Brázdil, Tomáš
last_name: Brázdil
- first_name: Antonín
full_name: Kučera, Antonín
last_name: Kučera
- first_name: Petr
full_name: Novotny, Petr
id: 3CC3B868-F248-11E8-B48F-1D18A9856A87
last_name: Novotny
citation:
ama: 'Brázdil T, Kučera A, Novotný P. Optimizing the expected mean payoff in Energy
Markov Decision Processes. In: Vol 9938. Springer; 2016:32-49. doi:10.1007/978-3-319-46520-3_3'
apa: 'Brázdil, T., Kučera, A., & Novotný, P. (2016). Optimizing the expected
mean payoff in Energy Markov Decision Processes (Vol. 9938, pp. 32–49). Presented
at the ATVA: Automated Technology for Verification and Analysis, Chiba, Japan:
Springer. https://doi.org/10.1007/978-3-319-46520-3_3'
chicago: Brázdil, Tomáš, Antonín Kučera, and Petr Novotný. “Optimizing the Expected
Mean Payoff in Energy Markov Decision Processes,” 9938:32–49. Springer, 2016.
https://doi.org/10.1007/978-3-319-46520-3_3.
ieee: 'T. Brázdil, A. Kučera, and P. Novotný, “Optimizing the expected mean payoff
in Energy Markov Decision Processes,” presented at the ATVA: Automated Technology
for Verification and Analysis, Chiba, Japan, 2016, vol. 9938, pp. 32–49.'
ista: 'Brázdil T, Kučera A, Novotný P. 2016. Optimizing the expected mean payoff
in Energy Markov Decision Processes. ATVA: Automated Technology for Verification
and Analysis, LNCS, vol. 9938, 32–49.'
mla: Brázdil, Tomáš, et al. Optimizing the Expected Mean Payoff in Energy Markov
Decision Processes. Vol. 9938, Springer, 2016, pp. 32–49, doi:10.1007/978-3-319-46520-3_3.
short: T. Brázdil, A. Kučera, P. Novotný, in:, Springer, 2016, pp. 32–49.
conference:
end_date: 2016-10-20
location: Chiba, Japan
name: 'ATVA: Automated Technology for Verification and Analysis'
start_date: 2016-10-17
date_created: 2018-12-11T11:51:23Z
date_published: 2016-09-22T00:00:00Z
date_updated: 2021-01-12T06:49:53Z
day: '22'
department:
- _id: KrCh
doi: 10.1007/978-3-319-46520-3_3
ec_funded: 1
intvolume: ' 9938'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1607.00678
month: '09'
oa: 1
oa_version: Preprint
page: 32 - 49
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication_status: published
publisher: Springer
publist_id: '5943'
quality_controlled: '1'
scopus_import: 1
status: public
title: Optimizing the expected mean payoff in Energy Markov Decision Processes
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 9938
year: '2016'
...
---
_id: '1327'
abstract:
- lang: eng
text: 'We consider partially observable Markov decision processes (POMDPs) with
a set of target states and positive integer costs associated with every transition.
The traditional optimization objective (stochastic shortest path) asks to minimize
the expected total cost until the target set is reached. We extend the traditional
framework of POMDPs to model energy consumption, which represents a hard constraint.
The energy levels may increase and decrease with transitions, and the hard constraint
requires that the energy level must remain positive in all steps till the target
is reached. First, we present a novel algorithm for solving POMDPs with energy
levels, developing on existing POMDP solvers and using RTDP as its main method.
Our second contribution is related to policy representation. For larger POMDP
instances the policies computed by existing solvers are too large to be understandable.
We present an automated procedure based on machine learning techniques that automatically
extracts important decisions of the policy allowing us to compute succinct human
readable policies. Finally, we show experimentally that our algorithm performs
well and computes succinct policies on a number of POMDP instances from the literature
that were naturally enhanced with energy levels. '
author:
- first_name: Tomáš
full_name: Brázdil, Tomáš
last_name: Brázdil
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Martin
full_name: Chmelik, Martin
id: 3624234E-F248-11E8-B48F-1D18A9856A87
last_name: Chmelik
- first_name: Anchit
full_name: Gupta, Anchit
last_name: Gupta
- first_name: Petr
full_name: Novotny, Petr
id: 3CC3B868-F248-11E8-B48F-1D18A9856A87
last_name: Novotny
citation:
ama: 'Brázdil T, Chatterjee K, Chmelik M, Gupta A, Novotný P. Stochastic shortest
path with energy constraints in POMDPs. In: Proceedings of the 15th International
Conference on Autonomous Agents and Multiagent Systems. ACM; 2016:1465-1466.'
apa: 'Brázdil, T., Chatterjee, K., Chmelik, M., Gupta, A., & Novotný, P. (2016).
Stochastic shortest path with energy constraints in POMDPs. In Proceedings
of the 15th International Conference on Autonomous Agents and Multiagent Systems
(pp. 1465–1466). Singapore: ACM.'
chicago: Brázdil, Tomáš, Krishnendu Chatterjee, Martin Chmelik, Anchit Gupta, and
Petr Novotný. “Stochastic Shortest Path with Energy Constraints in POMDPs.” In
Proceedings of the 15th International Conference on Autonomous Agents and Multiagent
Systems, 1465–66. ACM, 2016.
ieee: T. Brázdil, K. Chatterjee, M. Chmelik, A. Gupta, and P. Novotný, “Stochastic
shortest path with energy constraints in POMDPs,” in Proceedings of the 15th
International Conference on Autonomous Agents and Multiagent Systems, Singapore,
2016, pp. 1465–1466.
ista: 'Brázdil T, Chatterjee K, Chmelik M, Gupta A, Novotný P. 2016. Stochastic
shortest path with energy constraints in POMDPs. Proceedings of the 15th International
Conference on Autonomous Agents and Multiagent Systems. AAMAS: Autonomous Agents
& Multiagent Systems, 1465–1466.'
mla: Brázdil, Tomáš, et al. “Stochastic Shortest Path with Energy Constraints in
POMDPs.” Proceedings of the 15th International Conference on Autonomous Agents
and Multiagent Systems, ACM, 2016, pp. 1465–66.
short: T. Brázdil, K. Chatterjee, M. Chmelik, A. Gupta, P. Novotný, in:, Proceedings
of the 15th International Conference on Autonomous Agents and Multiagent Systems,
ACM, 2016, pp. 1465–1466.
conference:
end_date: 2016-05-13
location: Singapore
name: 'AAMAS: Autonomous Agents & Multiagent Systems'
start_date: 2016-05-09
date_created: 2018-12-11T11:51:23Z
date_published: 2016-01-01T00:00:00Z
date_updated: 2021-01-12T06:49:54Z
day: '01'
department:
- _id: KrCh
ec_funded: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1602.07565
month: '01'
oa: 1
oa_version: Preprint
page: 1465 - 1466
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
publication: Proceedings of the 15th International Conference on Autonomous Agents
and Multiagent Systems
publication_status: published
publisher: ACM
publist_id: '5942'
quality_controlled: '1'
scopus_import: 1
status: public
title: Stochastic shortest path with energy constraints in POMDPs
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
year: '2016'
...
---
_id: '1328'
abstract:
- lang: eng
text: Hole spins have gained considerable interest in the past few years due to
their potential for fast electrically controlled qubits. Here, we study holes
confined in Ge hut wires, a so-far unexplored type of nanostructure. Low-temperature
magnetotransport measurements reveal a large anisotropy between the in-plane and
out-of-plane g-factors of up to 18. Numerical simulations verify that this large
anisotropy originates from a confined wave function of heavy-hole character. A
light-hole admixture of less than 1% is estimated for the states of lowest energy,
leading to a surprisingly large reduction of the out-of-plane g-factors compared
with those for pure heavy holes. Given this tiny light-hole contribution, the
spin lifetimes are expected to be very long, even in isotopically nonpurified
samples.
acknowledgement: 'The work was supported by the EC FP7 ICT project SiSPIN no. 323841,
the EC FP7 ICT project PAMS no. 610446, the ERC Starting Grant no. 335497, the FWF-I-1190-N20
project, and the Swiss NSF. We acknowledge F. Schäffler for fruitful discussions
related to the hut wire growth and for giving us access to the molecular beam epitaxy
system, M. Schatzl for her support in electron beam lithography, and V. Jadris ̌ko
for helping us with the COMSOL simulations. Finally, we thank G. Bauer for his continuous
support. '
author:
- first_name: Hannes
full_name: Watzinger, Hannes
id: 35DF8E50-F248-11E8-B48F-1D18A9856A87
last_name: Watzinger
- first_name: Christoph
full_name: Kloeffel, Christoph
last_name: Kloeffel
- first_name: Lada
full_name: Vukusic, Lada
id: 31E9F056-F248-11E8-B48F-1D18A9856A87
last_name: Vukusic
orcid: 0000-0003-2424-8636
- first_name: Marta
full_name: Rossell, Marta
last_name: Rossell
- first_name: Violetta
full_name: Sessi, Violetta
last_name: Sessi
- first_name: Josip
full_name: Kukucka, Josip
id: 3F5D8856-F248-11E8-B48F-1D18A9856A87
last_name: Kukucka
- first_name: Raimund
full_name: Kirchschlager, Raimund
last_name: Kirchschlager
- first_name: Elisabeth
full_name: Lausecker, Elisabeth
id: 33662F76-F248-11E8-B48F-1D18A9856A87
last_name: Lausecker
- first_name: Alisha
full_name: Truhlar, Alisha
id: 49CBC780-F248-11E8-B48F-1D18A9856A87
last_name: Truhlar
- first_name: Martin
full_name: Glaser, Martin
last_name: Glaser
- first_name: Armando
full_name: Rastelli, Armando
last_name: Rastelli
- first_name: Andreas
full_name: Fuhrer, Andreas
last_name: Fuhrer
- first_name: Daniel
full_name: Loss, Daniel
last_name: Loss
- first_name: Georgios
full_name: Katsaros, Georgios
id: 38DB5788-F248-11E8-B48F-1D18A9856A87
last_name: Katsaros
orcid: 0000-0001-8342-202X
citation:
ama: Watzinger H, Kloeffel C, Vukušić L, et al. Heavy-hole states in germanium hut
wires. Nano Letters. 2016;16(11):6879-6885. doi:10.1021/acs.nanolett.6b02715
apa: Watzinger, H., Kloeffel, C., Vukušić, L., Rossell, M., Sessi, V., Kukucka,
J., … Katsaros, G. (2016). Heavy-hole states in germanium hut wires. Nano Letters.
American Chemical Society. https://doi.org/10.1021/acs.nanolett.6b02715
chicago: Watzinger, Hannes, Christoph Kloeffel, Lada Vukušić, Marta Rossell, Violetta
Sessi, Josip Kukucka, Raimund Kirchschlager, et al. “Heavy-Hole States in Germanium
Hut Wires.” Nano Letters. American Chemical Society, 2016. https://doi.org/10.1021/acs.nanolett.6b02715.
ieee: H. Watzinger et al., “Heavy-hole states in germanium hut wires,” Nano
Letters, vol. 16, no. 11. American Chemical Society, pp. 6879–6885, 2016.
ista: Watzinger H, Kloeffel C, Vukušić L, Rossell M, Sessi V, Kukucka J, Kirchschlager
R, Lausecker E, Truhlar A, Glaser M, Rastelli A, Fuhrer A, Loss D, Katsaros G.
2016. Heavy-hole states in germanium hut wires. Nano Letters. 16(11), 6879–6885.
mla: Watzinger, Hannes, et al. “Heavy-Hole States in Germanium Hut Wires.” Nano
Letters, vol. 16, no. 11, American Chemical Society, 2016, pp. 6879–85, doi:10.1021/acs.nanolett.6b02715.
short: H. Watzinger, C. Kloeffel, L. Vukušić, M. Rossell, V. Sessi, J. Kukucka,
R. Kirchschlager, E. Lausecker, A. Truhlar, M. Glaser, A. Rastelli, A. Fuhrer,
D. Loss, G. Katsaros, Nano Letters 16 (2016) 6879–6885.
date_created: 2018-12-11T11:51:24Z
date_published: 2016-09-22T00:00:00Z
date_updated: 2023-09-07T13:15:02Z
day: '22'
ddc:
- '539'
department:
- _id: GeKa
doi: 10.1021/acs.nanolett.6b02715
ec_funded: 1
file:
- access_level: open_access
checksum: b63feece90d7b620ece49ca632e34ff3
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:14:04Z
date_updated: 2020-07-14T12:44:44Z
file_id: '5053'
file_name: IST-2016-664-v1+1_acs.nanolett.6b02715.pdf
file_size: 535121
relation: main_file
file_date_updated: 2020-07-14T12:44:44Z
has_accepted_license: '1'
intvolume: ' 16'
issue: '11'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: 6879 - 6885
project:
- _id: 25517E86-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '335497'
name: Towards Spin qubits and Majorana fermions in Germanium selfassembled hut-wires
publication: Nano Letters
publication_status: published
publisher: American Chemical Society
publist_id: '5941'
pubrep_id: '664'
quality_controlled: '1'
related_material:
record:
- id: '7977'
relation: popular_science
status: for_moderation
- id: '7996'
relation: dissertation_contains
status: public
scopus_import: 1
status: public
title: Heavy-hole states in germanium hut wires
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 16
year: '2016'
...
---
_id: '1329'
abstract:
- lang: eng
text: Daphnia species have become models for ecological genomics and exhibit interesting
features, such as high phenotypic plasticity and a densely packed genome with
many lineage-specific genes. They are also cyclic parthenogenetic, with alternating
asexual and sexual cycles and environmental sex determination. Here, we present
a de novo transcriptome assembly of over 32,000 D. galeata genes and use it to
investigate gene expression in females and spontaneously produced males of two
clonal lines derived from lakes in Germany and the Czech Republic. We find that
only a low percentage (18%) of genes shows sex-biased expression and that there
are many more female-biased gene (FBG) than male-biased gene (MBG). Furthermore,
FBGs tend to be more conserved between species than MBGs in both sequence and
expression. These patterns may be a consequence of cyclic parthenogenesis leading
to a relaxation of purifying selection on MBGs. The two clonal lines show considerable
differences in both number and identity of sex-biased genes, suggesting that they
may have reproductive strategies differing in their investment in sexual reproduction.
Orthologs of key genes in the sex determination and juvenile hormone pathways,
which are thought to be important for the transition from asexual to sexual reproduction,
are present in D. galeata and highly conserved among Daphnia species.
acknowledgement: This study was financially supported by individual grants from the
Volkswagen Stiftung (to M.C.), the Deutsche Forschungsgemeinschaft (grant PA 903/6
to J.P.) and the DAAD (to A.K.H.). The authors would like to thank I. Schrank, L.
Theodosiou, M. Kredler, C. Laforsch, J. Wolinska, J. Griebel, R. Jaenichen, and
K. Otte for providing the necessary resources and help for maintaining Daphnia cultures
in the laboratory. H. Lainer supported us for the molecular laboratory work. D.
Gilbert and J. K. Colbourne contributed ideas for the bioinformatics analysis, and
L. Hardulak did the orthology mapping including more insect species. This study
was financially supported by individual grants from the Volkswagen Stiftung (to
M.C.), the Deutsche Forschungsgemeinschaft (grant PA 903/6 to J.P.) and the DAAD
(to A.K.H.). This work benefits from and contributes to the Daphnia Genomics Consortium.
author:
- first_name: Ann K
full_name: Huylmans, Ann K
id: 4C0A3874-F248-11E8-B48F-1D18A9856A87
last_name: Huylmans
orcid: 0000-0001-8871-4961
- first_name: Alberto
full_name: López Ezquerra, Alberto
last_name: López Ezquerra
- first_name: John
full_name: Parsch, John
last_name: Parsch
- first_name: Mathilde
full_name: Cordellier, Mathilde
last_name: Cordellier
citation:
ama: Huylmans AK, López Ezquerra A, Parsch J, Cordellier M. De novo transcriptome
assembly and sex-biased gene expression in the cyclical parthenogenetic Daphnia
galeata. Genome Biology and Evolution. 2016;8(10):3120-3139. doi:10.1093/gbe/evw221
apa: Huylmans, A. K., López Ezquerra, A., Parsch, J., & Cordellier, M. (2016).
De novo transcriptome assembly and sex-biased gene expression in the cyclical
parthenogenetic Daphnia galeata. Genome Biology and Evolution. Oxford University
Press. https://doi.org/10.1093/gbe/evw221
chicago: Huylmans, Ann K, Alberto López Ezquerra, John Parsch, and Mathilde Cordellier.
“De Novo Transcriptome Assembly and Sex-Biased Gene Expression in the Cyclical
Parthenogenetic Daphnia Galeata.” Genome Biology and Evolution. Oxford
University Press, 2016. https://doi.org/10.1093/gbe/evw221.
ieee: A. K. Huylmans, A. López Ezquerra, J. Parsch, and M. Cordellier, “De novo
transcriptome assembly and sex-biased gene expression in the cyclical parthenogenetic
Daphnia galeata,” Genome Biology and Evolution, vol. 8, no. 10. Oxford
University Press, pp. 3120–3139, 2016.
ista: Huylmans AK, López Ezquerra A, Parsch J, Cordellier M. 2016. De novo transcriptome
assembly and sex-biased gene expression in the cyclical parthenogenetic Daphnia
galeata. Genome Biology and Evolution. 8(10), 3120–3139.
mla: Huylmans, Ann K., et al. “De Novo Transcriptome Assembly and Sex-Biased Gene
Expression in the Cyclical Parthenogenetic Daphnia Galeata.” Genome Biology
and Evolution, vol. 8, no. 10, Oxford University Press, 2016, pp. 3120–39,
doi:10.1093/gbe/evw221.
short: A.K. Huylmans, A. López Ezquerra, J. Parsch, M. Cordellier, Genome Biology
and Evolution 8 (2016) 3120–3139.
date_created: 2018-12-11T11:51:24Z
date_published: 2016-10-01T00:00:00Z
date_updated: 2021-01-12T06:49:55Z
day: '01'
ddc:
- '576'
department:
- _id: BeVi
doi: 10.1093/gbe/evw221
file:
- access_level: open_access
checksum: 25c7adcb452d39d3b6343ff4b57a652d
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:12:06Z
date_updated: 2020-07-14T12:44:44Z
file_id: '4924'
file_name: IST-2016-663-v1+1_Genome_Biol_Evol-2016-Huylmans-3120-39.pdf
file_size: 1406265
relation: main_file
file_date_updated: 2020-07-14T12:44:44Z
has_accepted_license: '1'
intvolume: ' 8'
issue: '10'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc/4.0/
month: '10'
oa: 1
oa_version: Published Version
page: 3120 - 3139
publication: Genome Biology and Evolution
publication_status: published
publisher: Oxford University Press
publist_id: '5940'
pubrep_id: '663'
quality_controlled: '1'
scopus_import: 1
status: public
title: De novo transcriptome assembly and sex-biased gene expression in the cyclical
parthenogenetic Daphnia galeata
tmp:
image: /images/cc_by_nc.png
legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
short: CC BY-NC (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2016'
...
---
_id: '1330'
abstract:
- lang: eng
text: In this paper we investigate the existence of closed billiard trajectories
in not necessarily smooth convex bodies. In particular, we show that if a body
K ⊂ Rd has the property that the tangent cone of every non-smooth point q ∉ ∂K
is acute (in a certain sense), then there is a closed billiard trajectory in K.
acknowledgement: Supported by People Programme (Marie Curie Actions) of the European
Union’s Seventh Framework Programme (FP7/2007-2013) under REA grant agreement n°[291734].
Supported by the Russian Foundation for Basic Research grant 15-31-20403 (mol a
ved), by the Russian Foundation for Basic Research grant 15-01-99563 A, in part
by the Moebius Contest Foundation for Young Scientists, and in part by the Simons
Foundation.
author:
- first_name: Arseniy
full_name: Akopyan, Arseniy
id: 430D2C90-F248-11E8-B48F-1D18A9856A87
last_name: Akopyan
orcid: 0000-0002-2548-617X
- first_name: Alexey
full_name: Balitskiy, Alexey
last_name: Balitskiy
citation:
ama: Akopyan A, Balitskiy A. Billiards in convex bodies with acute angles. Israel
Journal of Mathematics. 2016;216(2):833-845. doi:10.1007/s11856-016-1429-z
apa: Akopyan, A., & Balitskiy, A. (2016). Billiards in convex bodies with acute
angles. Israel Journal of Mathematics. Springer. https://doi.org/10.1007/s11856-016-1429-z
chicago: Akopyan, Arseniy, and Alexey Balitskiy. “Billiards in Convex Bodies with
Acute Angles.” Israel Journal of Mathematics. Springer, 2016. https://doi.org/10.1007/s11856-016-1429-z.
ieee: A. Akopyan and A. Balitskiy, “Billiards in convex bodies with acute angles,”
Israel Journal of Mathematics, vol. 216, no. 2. Springer, pp. 833–845,
2016.
ista: Akopyan A, Balitskiy A. 2016. Billiards in convex bodies with acute angles.
Israel Journal of Mathematics. 216(2), 833–845.
mla: Akopyan, Arseniy, and Alexey Balitskiy. “Billiards in Convex Bodies with Acute
Angles.” Israel Journal of Mathematics, vol. 216, no. 2, Springer, 2016,
pp. 833–45, doi:10.1007/s11856-016-1429-z.
short: A. Akopyan, A. Balitskiy, Israel Journal of Mathematics 216 (2016) 833–845.
date_created: 2018-12-11T11:51:24Z
date_published: 2016-10-15T00:00:00Z
date_updated: 2021-01-12T06:49:56Z
day: '15'
department:
- _id: HeEd
doi: 10.1007/s11856-016-1429-z
ec_funded: 1
intvolume: ' 216'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1506.06014
month: '10'
oa: 1
oa_version: Preprint
page: 833 - 845
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: Israel Journal of Mathematics
publication_status: published
publisher: Springer
publist_id: '5938'
quality_controlled: '1'
scopus_import: 1
status: public
title: Billiards in convex bodies with acute angles
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 216
year: '2016'
...
---
_id: '1331'
abstract:
- lang: eng
text: 'Cytokinin is a phytohormone that is well known for its roles in numerous
plant growth and developmental processes, yet it has also been linked to abiotic
stress response in a less defined manner. Arabidopsis (Arabidopsis thaliana) Cytokinin
Response Factor 6 (CRF6) is a cytokinin-responsive AP2/ERF-family transcription
factor that, through the cytokinin signaling pathway, plays a key role in the
inhibition of dark-induced senescence. CRF6 expression is also induced by oxidative
stress, and here we show a novel function for CRF6 in relation to oxidative stress
and identify downstream transcriptional targets of CRF6 that are repressed in
response to oxidative stress. Analysis of transcriptomic changes in wild-type
and crf6 mutant plants treated with H2O2 identified CRF6-dependent differentially
expressed transcripts, many of which were repressed rather than induced. Moreover,
many repressed genes also show decreased expression in 35S:CRF6 overexpressing
plants. Together, these findings suggest that CRF6 functions largely as a transcriptional
repressor. Interestingly, among the H2O2 repressed CRF6-dependent transcripts
was a set of five genes associated with cytokinin processes: (signaling) ARR6,
ARR9, ARR11, (biosynthesis) LOG7, and (transport) ABCG14. We have examined mutants
of these cytokinin-associated target genes to reveal novel connections to oxidative
stress. Further examination of CRF6-DNA interactions indicated that CRF6 may regulate
its targets both directly and indirectly. Together, this shows that CRF6 functions
during oxidative stress as a negative regulator to control this cytokinin-associated
module of CRF6- dependent genes and establishes a novel connection between cytokinin
and oxidative stress response.'
acknowledgement: "This work was financially supported by the following: The Alabama
Agricultural Experiment Station HATCH grants 370222-310010-2055 and 370225-310006-2055
for funding to P.J.Z., E.A.K, A.M.P., and A.M.R. P.J.Z. and E.A.K were supported
by an Auburn University Cellular and Molecular Biosciences Research Fellowship.
I.D.C. is a postdoctoral fellow of the Research Foundation Flanders (FWO) (FWO/PDO14/043)
and is also supported by FWO travel\r\ngrant 12N2415N. F.V.B. was supported by grants
from the Interuniversity Attraction Poles Programme (IUAP P7/29 MARS) initiated
by the Belgian Science Policy Office and Ghent University (Multidisciplinary Research
Partnership Biotechnology for a Sustainable Economy, grant 01MRB510W)."
article_processing_charge: No
article_type: original
author:
- first_name: Paul
full_name: Zwack, Paul
last_name: Zwack
- first_name: Inge
full_name: De Clercq, Inge
last_name: De Clercq
- first_name: Timothy
full_name: Howton, Timothy
last_name: Howton
- first_name: H Tucker
full_name: Hallmark, H Tucker
last_name: Hallmark
- first_name: Andrej
full_name: Hurny, Andrej
id: 4DC4AF46-F248-11E8-B48F-1D18A9856A87
last_name: Hurny
- first_name: Erika
full_name: Keshishian, Erika
last_name: Keshishian
- first_name: Alyssa
full_name: Parish, Alyssa
last_name: Parish
- first_name: Eva
full_name: Benková, Eva
id: 38F4F166-F248-11E8-B48F-1D18A9856A87
last_name: Benková
orcid: 0000-0002-8510-9739
- first_name: M Shahid
full_name: Mukhtar, M Shahid
last_name: Mukhtar
- first_name: Frank
full_name: Van Breusegem, Frank
last_name: Van Breusegem
- first_name: Aaron
full_name: Rashotte, Aaron
last_name: Rashotte
citation:
ama: Zwack P, De Clercq I, Howton T, et al. Cytokinin response factor 6 represses
cytokinin-associated genes during oxidative stress. Plant Physiology. 2016;172(2):1249-1258.
doi:10.1104/pp.16.00415
apa: Zwack, P., De Clercq, I., Howton, T., Hallmark, H. T., Hurny, A., Keshishian,
E., … Rashotte, A. (2016). Cytokinin response factor 6 represses cytokinin-associated
genes during oxidative stress. Plant Physiology. American Society of Plant
Biologists. https://doi.org/10.1104/pp.16.00415
chicago: Zwack, Paul, Inge De Clercq, Timothy Howton, H Tucker Hallmark, Andrej
Hurny, Erika Keshishian, Alyssa Parish, et al. “Cytokinin Response Factor 6 Represses
Cytokinin-Associated Genes during Oxidative Stress.” Plant Physiology.
American Society of Plant Biologists, 2016. https://doi.org/10.1104/pp.16.00415.
ieee: P. Zwack et al., “Cytokinin response factor 6 represses cytokinin-associated
genes during oxidative stress,” Plant Physiology, vol. 172, no. 2. American
Society of Plant Biologists, pp. 1249–1258, 2016.
ista: Zwack P, De Clercq I, Howton T, Hallmark HT, Hurny A, Keshishian E, Parish
A, Benková E, Mukhtar MS, Van Breusegem F, Rashotte A. 2016. Cytokinin response
factor 6 represses cytokinin-associated genes during oxidative stress. Plant Physiology.
172(2), 1249–1258.
mla: Zwack, Paul, et al. “Cytokinin Response Factor 6 Represses Cytokinin-Associated
Genes during Oxidative Stress.” Plant Physiology, vol. 172, no. 2, American
Society of Plant Biologists, 2016, pp. 1249–58, doi:10.1104/pp.16.00415.
short: P. Zwack, I. De Clercq, T. Howton, H.T. Hallmark, A. Hurny, E. Keshishian,
A. Parish, E. Benková, M.S. Mukhtar, F. Van Breusegem, A. Rashotte, Plant Physiology
172 (2016) 1249–1258.
date_created: 2018-12-11T11:51:25Z
date_published: 2016-10-02T00:00:00Z
date_updated: 2022-05-24T09:26:03Z
day: '02'
department:
- _id: EvBe
doi: 10.1104/pp.16.00415
intvolume: ' 172'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1104/pp.16.00415
month: '10'
oa: 1
oa_version: Published Version
page: 1249 - 1258
publication: Plant Physiology
publication_identifier:
eissn:
- 1532-2548
issn:
- 0032-0889
publication_status: published
publisher: American Society of Plant Biologists
publist_id: '5937'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Cytokinin response factor 6 represses cytokinin-associated genes during oxidative
stress
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 172
year: '2016'
...
---
_id: '1332'
abstract:
- lang: eng
text: Antibiotic-sensitive and -resistant bacteria coexist in natural environments
with low, if detectable, antibiotic concentrations. Except possibly around localized
antibiotic sources, where resistance can provide a strong advantage, bacterial
fitness is dominated by stresses unaffected by resistance to the antibiotic. How
do such mixed and heterogeneous conditions influence the selective advantage or
disadvantage of antibiotic resistance? Here we find that sub-inhibitory levels
of tetracyclines potentiate selection for or against tetracycline resistance around
localized sources of almost any toxin or stress. Furthermore, certain stresses
generate alternating rings of selection for and against resistance around a localized
source of the antibiotic. In these conditions, localized antibiotic sources, even
at high strengths, can actually produce a net selection against resistance to
the antibiotic. Our results show that interactions between the effects of an antibiotic
and other stresses in inhomogeneous environments can generate pervasive, complex
patterns of selection both for and against antibiotic resistance.
acknowledgement: This work was partially supported by US National Institutes of Health
grant R01-GM081617, Israeli Centers of Research Excellence I-CORE Program ISF Grant
No. 152/11, and the European Research Council FP7 ERC Grant 281891.
article_number: '10333'
author:
- first_name: Remy P
full_name: Chait, Remy P
id: 3464AE84-F248-11E8-B48F-1D18A9856A87
last_name: Chait
orcid: 0000-0003-0876-3187
- first_name: Adam
full_name: Palmer, Adam
last_name: Palmer
- first_name: Idan
full_name: Yelin, Idan
last_name: Yelin
- first_name: Roy
full_name: Kishony, Roy
last_name: Kishony
citation:
ama: Chait RP, Palmer A, Yelin I, Kishony R. Pervasive selection for and against
antibiotic resistance in inhomogeneous multistress environments. Nature Communications.
2016;7. doi:10.1038/ncomms10333
apa: Chait, R. P., Palmer, A., Yelin, I., & Kishony, R. (2016). Pervasive selection
for and against antibiotic resistance in inhomogeneous multistress environments.
Nature Communications. Nature Publishing Group. https://doi.org/10.1038/ncomms10333
chicago: Chait, Remy P, Adam Palmer, Idan Yelin, and Roy Kishony. “Pervasive Selection
for and against Antibiotic Resistance in Inhomogeneous Multistress Environments.”
Nature Communications. Nature Publishing Group, 2016. https://doi.org/10.1038/ncomms10333.
ieee: R. P. Chait, A. Palmer, I. Yelin, and R. Kishony, “Pervasive selection for
and against antibiotic resistance in inhomogeneous multistress environments,”
Nature Communications, vol. 7. Nature Publishing Group, 2016.
ista: Chait RP, Palmer A, Yelin I, Kishony R. 2016. Pervasive selection for and
against antibiotic resistance in inhomogeneous multistress environments. Nature
Communications. 7, 10333.
mla: Chait, Remy P., et al. “Pervasive Selection for and against Antibiotic Resistance
in Inhomogeneous Multistress Environments.” Nature Communications, vol.
7, 10333, Nature Publishing Group, 2016, doi:10.1038/ncomms10333.
short: R.P. Chait, A. Palmer, I. Yelin, R. Kishony, Nature Communications 7 (2016).
date_created: 2018-12-11T11:51:25Z
date_published: 2016-01-20T00:00:00Z
date_updated: 2021-01-12T06:49:57Z
day: '20'
ddc:
- '570'
- '579'
department:
- _id: CaGu
- _id: GaTk
doi: 10.1038/ncomms10333
file:
- access_level: open_access
checksum: ef147bcbb8bd37e9079cf3ce06f5815d
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:13:52Z
date_updated: 2020-07-14T12:44:44Z
file_id: '5039'
file_name: IST-2016-662-v1+1_ncomms10333.pdf
file_size: 1844107
relation: main_file
file_date_updated: 2020-07-14T12:44:44Z
has_accepted_license: '1'
intvolume: ' 7'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
publication: Nature Communications
publication_status: published
publisher: Nature Publishing Group
publist_id: '5936'
pubrep_id: '662'
quality_controlled: '1'
scopus_import: 1
status: public
title: Pervasive selection for and against antibiotic resistance in inhomogeneous
multistress environments
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2016'
...
---
_id: '1333'
abstract:
- lang: eng
text: Social dilemmas force players to balance between personal and collective gain.
In many dilemmas, such as elected governments negotiating climate-change mitigation
measures, the decisions are made not by individual players but by their representatives.
However, the behaviour of representatives in social dilemmas has not been investigated
experimentally. Here inspired by the negotiations for greenhouse-gas emissions
reductions, we experimentally study a collective-risk social dilemma that involves
representatives deciding on behalf of their fellow group members. Representatives
can be re-elected or voted out after each consecutive collective-risk game. Selfish
players are preferentially elected and are hence found most frequently in the
"representatives" treatment. Across all treatments, we identify the
selfish players as extortioners. As predicted by our mathematical model, their
steadfast strategies enforce cooperation from fair players who finally compensate
almost completely the deficit caused by the extortionate co-players. Everybody
gains, but the extortionate representatives and their groups gain the most.
acknowledgement: We thank the students for participation; H.-J. Krambeck for writing
the software for the game; H. Arndt, T. Bakker, L. Becks, H. Brendelberger, S. Dobler
and T. Reusch for support; and the Max Planck Society for the Advancement of Science
for funding.
article_number: '10915'
author:
- first_name: Manfred
full_name: Milinski, Manfred
last_name: Milinski
- first_name: Christian
full_name: Hilbe, Christian
id: 2FDF8F3C-F248-11E8-B48F-1D18A9856A87
last_name: Hilbe
orcid: 0000-0001-5116-955X
- first_name: Dirk
full_name: Semmann, Dirk
last_name: Semmann
- first_name: Ralf
full_name: Sommerfeld, Ralf
last_name: Sommerfeld
- first_name: Jochem
full_name: Marotzke, Jochem
last_name: Marotzke
citation:
ama: Milinski M, Hilbe C, Semmann D, Sommerfeld R, Marotzke J. Humans choose representatives
who enforce cooperation in social dilemmas through extortion. Nature Communications.
2016;7. doi:10.1038/ncomms10915
apa: Milinski, M., Hilbe, C., Semmann, D., Sommerfeld, R., & Marotzke, J. (2016).
Humans choose representatives who enforce cooperation in social dilemmas through
extortion. Nature Communications. Nature Publishing Group. https://doi.org/10.1038/ncomms10915
chicago: Milinski, Manfred, Christian Hilbe, Dirk Semmann, Ralf Sommerfeld, and
Jochem Marotzke. “Humans Choose Representatives Who Enforce Cooperation in Social
Dilemmas through Extortion.” Nature Communications. Nature Publishing Group,
2016. https://doi.org/10.1038/ncomms10915.
ieee: M. Milinski, C. Hilbe, D. Semmann, R. Sommerfeld, and J. Marotzke, “Humans
choose representatives who enforce cooperation in social dilemmas through extortion,”
Nature Communications, vol. 7. Nature Publishing Group, 2016.
ista: Milinski M, Hilbe C, Semmann D, Sommerfeld R, Marotzke J. 2016. Humans choose
representatives who enforce cooperation in social dilemmas through extortion.
Nature Communications. 7, 10915.
mla: Milinski, Manfred, et al. “Humans Choose Representatives Who Enforce Cooperation
in Social Dilemmas through Extortion.” Nature Communications, vol. 7, 10915,
Nature Publishing Group, 2016, doi:10.1038/ncomms10915.
short: M. Milinski, C. Hilbe, D. Semmann, R. Sommerfeld, J. Marotzke, Nature Communications
7 (2016).
date_created: 2018-12-11T11:51:25Z
date_published: 2016-03-07T00:00:00Z
date_updated: 2021-01-12T06:49:57Z
day: '07'
ddc:
- '519'
- '530'
- '599'
department:
- _id: KrCh
doi: 10.1038/ncomms10915
file:
- access_level: open_access
checksum: 9ea0d7ce59a555a1cb8353d5559407cb
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:10:44Z
date_updated: 2020-07-14T12:44:44Z
file_id: '4834'
file_name: IST-2016-661-v1+1_ncomms10915.pdf
file_size: 1432577
relation: main_file
file_date_updated: 2020-07-14T12:44:44Z
has_accepted_license: '1'
intvolume: ' 7'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
publication: Nature Communications
publication_status: published
publisher: Nature Publishing Group
publist_id: '5935'
pubrep_id: '661'
quality_controlled: '1'
scopus_import: 1
status: public
title: Humans choose representatives who enforce cooperation in social dilemmas through
extortion
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2016'
...