---
_id: '7736'
abstract:
- lang: eng
text: We develop a novel approach to identify regions of the genome underlying population
genetic differentiation in any genetic data where the underlying population structure
is unknown, or where the interest is assessing divergence along a gradient. By
combining the statistical framework for genome-wide association studies (GWASs)
with eigenvector decomposition (EigenGWAS), which is commonly used in population
genetics to characterize the structure of genetic data, loci under selection can
be identified without a requirement for discrete populations. We show through
theory and simulation that our approach can identify regions under selection along
gradients of ancestry, and in real data we confirm this by demonstrating LCT to
be under selection between HapMap CEU–TSI cohorts, and we then validate this selection
signal across European countries in the POPRES samples. HERC2 was also found to
be differentiated between both the CEU–TSI cohort and within the POPRES sample,
reflecting the likely anthropological differences in skin and hair colour between
northern and southern European populations. Controlling for population stratification
is of great importance in any quantitative genetic study and our approach also
provides a simple, fast and accurate way of predicting principal components in
independent samples. With ever increasing sample sizes across many fields, this
approach is likely to be greatly utilized to gain individual-level eigenvectors
avoiding the computational challenges associated with conducting singular value
decomposition in large data sets. We have developed freely available software,
Genetic Analysis Repository (GEAR), to facilitate the application of the methods.
article_processing_charge: No
article_type: original
author:
- first_name: G-B
full_name: Chen, G-B
last_name: Chen
- first_name: S H
full_name: Lee, S H
last_name: Lee
- first_name: Z-X
full_name: Zhu, Z-X
last_name: Zhu
- first_name: B
full_name: Benyamin, B
last_name: Benyamin
- first_name: Matthew Richard
full_name: Robinson, Matthew Richard
id: E5D42276-F5DA-11E9-8E24-6303E6697425
last_name: Robinson
orcid: 0000-0001-8982-8813
citation:
ama: 'Chen G-B, Lee SH, Zhu Z-X, Benyamin B, Robinson MR. EigenGWAS: Finding loci
under selection through genome-wide association studies of eigenvectors in structured
populations. Heredity. 2016;117:51-61. doi:10.1038/hdy.2016.25'
apa: 'Chen, G.-B., Lee, S. H., Zhu, Z.-X., Benyamin, B., & Robinson, M. R. (2016).
EigenGWAS: Finding loci under selection through genome-wide association studies
of eigenvectors in structured populations. Heredity. Springer Nature. https://doi.org/10.1038/hdy.2016.25'
chicago: 'Chen, G-B, S H Lee, Z-X Zhu, B Benyamin, and Matthew Richard Robinson.
“EigenGWAS: Finding Loci under Selection through Genome-Wide Association Studies
of Eigenvectors in Structured Populations.” Heredity. Springer Nature,
2016. https://doi.org/10.1038/hdy.2016.25.'
ieee: 'G.-B. Chen, S. H. Lee, Z.-X. Zhu, B. Benyamin, and M. R. Robinson, “EigenGWAS:
Finding loci under selection through genome-wide association studies of eigenvectors
in structured populations,” Heredity, vol. 117. Springer Nature, pp. 51–61,
2016.'
ista: 'Chen G-B, Lee SH, Zhu Z-X, Benyamin B, Robinson MR. 2016. EigenGWAS: Finding
loci under selection through genome-wide association studies of eigenvectors in
structured populations. Heredity. 117, 51–61.'
mla: 'Chen, G. B., et al. “EigenGWAS: Finding Loci under Selection through Genome-Wide
Association Studies of Eigenvectors in Structured Populations.” Heredity,
vol. 117, Springer Nature, 2016, pp. 51–61, doi:10.1038/hdy.2016.25.'
short: G.-B. Chen, S.H. Lee, Z.-X. Zhu, B. Benyamin, M.R. Robinson, Heredity 117
(2016) 51–61.
date_created: 2020-04-30T10:50:03Z
date_published: 2016-05-04T00:00:00Z
date_updated: 2021-01-12T08:15:11Z
day: '04'
doi: 10.1038/hdy.2016.25
extern: '1'
intvolume: ' 117'
language:
- iso: eng
month: '05'
oa_version: None
page: 51-61
publication: Heredity
publication_identifier:
issn:
- 0018-067X
- 1365-2540
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: 'EigenGWAS: Finding loci under selection through genome-wide association studies
of eigenvectors in structured populations'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 117
year: '2016'
...
---
_id: '7737'
abstract:
- lang: eng
text: Genome-wide association studies (GWAS) have identified thousands of genetic
variants associated with human complex traits. However, the genes or functional
DNA elements through which these variants exert their effects on the traits are
often unknown. We propose a method (called SMR) that integrates summary-level
data from GWAS with data from expression quantitative trait locus (eQTL) studies
to identify genes whose expression levels are associated with a complex trait
because of pleiotropy. We apply the method to five human complex traits using
GWAS data on up to 339,224 individuals and eQTL data on 5,311 individuals, and
we prioritize 126 genes (for example, TRAF1 and ANKRD55 for rheumatoid arthritis
and SNX19 and NMRAL1 for schizophrenia), of which 25 genes are new candidates;
77 genes are not the nearest annotated gene to the top associated GWAS SNP. These
genes provide important leads to design future functional studies to understand
the mechanism whereby DNA variation leads to complex trait variation.
article_processing_charge: No
article_type: original
author:
- first_name: Zhihong
full_name: Zhu, Zhihong
last_name: Zhu
- first_name: Futao
full_name: Zhang, Futao
last_name: Zhang
- first_name: Han
full_name: Hu, Han
last_name: Hu
- first_name: Andrew
full_name: Bakshi, Andrew
last_name: Bakshi
- first_name: Matthew Richard
full_name: Robinson, Matthew Richard
id: E5D42276-F5DA-11E9-8E24-6303E6697425
last_name: Robinson
orcid: 0000-0001-8982-8813
- first_name: Joseph E
full_name: Powell, Joseph E
last_name: Powell
- first_name: Grant W
full_name: Montgomery, Grant W
last_name: Montgomery
- first_name: Michael E
full_name: Goddard, Michael E
last_name: Goddard
- first_name: Naomi R
full_name: Wray, Naomi R
last_name: Wray
- first_name: Peter M
full_name: Visscher, Peter M
last_name: Visscher
- first_name: Jian
full_name: Yang, Jian
last_name: Yang
citation:
ama: Zhu Z, Zhang F, Hu H, et al. Integration of summary data from GWAS and eQTL
studies predicts complex trait gene targets. Nature Genetics. 2016;48(5):481-487.
doi:10.1038/ng.3538
apa: Zhu, Z., Zhang, F., Hu, H., Bakshi, A., Robinson, M. R., Powell, J. E., … Yang,
J. (2016). Integration of summary data from GWAS and eQTL studies predicts complex
trait gene targets. Nature Genetics. Springer Nature. https://doi.org/10.1038/ng.3538
chicago: Zhu, Zhihong, Futao Zhang, Han Hu, Andrew Bakshi, Matthew Richard Robinson,
Joseph E Powell, Grant W Montgomery, et al. “Integration of Summary Data from
GWAS and EQTL Studies Predicts Complex Trait Gene Targets.” Nature Genetics.
Springer Nature, 2016. https://doi.org/10.1038/ng.3538.
ieee: Z. Zhu et al., “Integration of summary data from GWAS and eQTL studies
predicts complex trait gene targets,” Nature Genetics, vol. 48, no. 5.
Springer Nature, pp. 481–487, 2016.
ista: Zhu Z, Zhang F, Hu H, Bakshi A, Robinson MR, Powell JE, Montgomery GW, Goddard
ME, Wray NR, Visscher PM, Yang J. 2016. Integration of summary data from GWAS
and eQTL studies predicts complex trait gene targets. Nature Genetics. 48(5),
481–487.
mla: Zhu, Zhihong, et al. “Integration of Summary Data from GWAS and EQTL Studies
Predicts Complex Trait Gene Targets.” Nature Genetics, vol. 48, no. 5,
Springer Nature, 2016, pp. 481–87, doi:10.1038/ng.3538.
short: Z. Zhu, F. Zhang, H. Hu, A. Bakshi, M.R. Robinson, J.E. Powell, G.W. Montgomery,
M.E. Goddard, N.R. Wray, P.M. Visscher, J. Yang, Nature Genetics 48 (2016) 481–487.
date_created: 2020-04-30T10:50:26Z
date_published: 2016-03-28T00:00:00Z
date_updated: 2021-01-12T08:15:11Z
day: '28'
doi: 10.1038/ng.3538
extern: '1'
intvolume: ' 48'
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1038/ng.3538
month: '03'
oa: 1
oa_version: Published Version
page: 481-487
publication: Nature Genetics
publication_identifier:
issn:
- 1061-4036
- 1546-1718
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Integration of summary data from GWAS and eQTL studies predicts complex trait
gene targets
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 48
year: '2016'
...
---
_id: '7760'
abstract:
- lang: eng
text: We propose a Widom-like scaling ansatz for the critical jamming transition.
Our ansatz for the elastic energy shows that the scaling of the energy, compressive
strain, shear strain, system size, pressure, shear stress, bulk modulus, and shear
modulus are all related to each other via scaling relations, with only three independent
scaling exponents. We extract the values of these exponents from already known
numerical or theoretical results, and we numerically verify the resulting predictions
of the scaling theory for the energy and residual shear stress. We also derive
a scaling relation between pressure and residual shear stress that yields insight
into why the shear and bulk moduli scale differently. Our theory shows that the
jamming transition exhibits an emergent scale invariance, setting the stage for
the potential development of a renormalization group theory for jamming.
article_processing_charge: No
article_type: original
author:
- first_name: Carl Peter
full_name: Goodrich, Carl Peter
id: EB352CD2-F68A-11E9-89C5-A432E6697425
last_name: Goodrich
orcid: 0000-0002-1307-5074
- first_name: Andrea J.
full_name: Liu, Andrea J.
last_name: Liu
- first_name: James P.
full_name: Sethna, James P.
last_name: Sethna
citation:
ama: Goodrich CP, Liu AJ, Sethna JP. Scaling ansatz for the jamming transition.
Proceedings of the National Academy of Sciences. 2016;113(35):9745-9750.
doi:10.1073/pnas.1601858113
apa: Goodrich, C. P., Liu, A. J., & Sethna, J. P. (2016). Scaling ansatz for
the jamming transition. Proceedings of the National Academy of Sciences.
Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1601858113
chicago: Goodrich, Carl Peter, Andrea J. Liu, and James P. Sethna. “Scaling Ansatz
for the Jamming Transition.” Proceedings of the National Academy of Sciences.
Proceedings of the National Academy of Sciences, 2016. https://doi.org/10.1073/pnas.1601858113.
ieee: C. P. Goodrich, A. J. Liu, and J. P. Sethna, “Scaling ansatz for the jamming
transition,” Proceedings of the National Academy of Sciences, vol. 113,
no. 35. Proceedings of the National Academy of Sciences, pp. 9745–9750, 2016.
ista: Goodrich CP, Liu AJ, Sethna JP. 2016. Scaling ansatz for the jamming transition.
Proceedings of the National Academy of Sciences. 113(35), 9745–9750.
mla: Goodrich, Carl Peter, et al. “Scaling Ansatz for the Jamming Transition.” Proceedings
of the National Academy of Sciences, vol. 113, no. 35, Proceedings of the
National Academy of Sciences, 2016, pp. 9745–50, doi:10.1073/pnas.1601858113.
short: C.P. Goodrich, A.J. Liu, J.P. Sethna, Proceedings of the National Academy
of Sciences 113 (2016) 9745–9750.
date_created: 2020-04-30T11:39:53Z
date_published: 2016-08-30T00:00:00Z
date_updated: 2021-01-12T08:15:21Z
day: '30'
doi: 10.1073/pnas.1601858113
extern: '1'
intvolume: ' 113'
issue: '35'
language:
- iso: eng
month: '08'
oa_version: None
page: 9745-9750
publication: Proceedings of the National Academy of Sciences
publication_identifier:
issn:
- 0027-8424
- 1091-6490
publication_status: published
publisher: Proceedings of the National Academy of Sciences
quality_controlled: '1'
status: public
title: Scaling ansatz for the jamming transition
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 113
year: '2016'
...
---
_id: '7761'
abstract:
- lang: eng
text: We study the effect of dilute pinning on the jamming transition. Pinning reduces
the average contact number needed to jam unpinned particles and shifts the jamming
threshold to lower densities, leading to a pinning susceptibility, χp. Our main
results are that this susceptibility obeys scaling form and diverges in the thermodynamic
limit as χp∝|ϕ−ϕ∞c|−γp where ϕ∞c is the jamming threshold in the absence of pins.
Finite-size scaling arguments yield these values with associated statistical (systematic)
errors γp=1.018±0.026(0.291) in d=2 and γp=1.534±0.120(0.822) in d=3. Logarithmic
corrections raise the exponent in d=2 to close to the d=3 value, although the
systematic errors are very large.
article_number: '235501'
article_processing_charge: No
article_type: original
author:
- first_name: Amy L.
full_name: Graves, Amy L.
last_name: Graves
- first_name: Samer
full_name: Nashed, Samer
last_name: Nashed
- first_name: Elliot
full_name: Padgett, Elliot
last_name: Padgett
- first_name: Carl Peter
full_name: Goodrich, Carl Peter
id: EB352CD2-F68A-11E9-89C5-A432E6697425
last_name: Goodrich
orcid: 0000-0002-1307-5074
- first_name: Andrea J.
full_name: Liu, Andrea J.
last_name: Liu
- first_name: James P.
full_name: Sethna, James P.
last_name: Sethna
citation:
ama: 'Graves AL, Nashed S, Padgett E, Goodrich CP, Liu AJ, Sethna JP. Pinning susceptibility:
The effect of dilute, quenched disorder on jamming. Physical Review Letters.
2016;116(23). doi:10.1103/physrevlett.116.235501'
apa: 'Graves, A. L., Nashed, S., Padgett, E., Goodrich, C. P., Liu, A. J., &
Sethna, J. P. (2016). Pinning susceptibility: The effect of dilute, quenched disorder
on jamming. Physical Review Letters. American Physical Society. https://doi.org/10.1103/physrevlett.116.235501'
chicago: 'Graves, Amy L., Samer Nashed, Elliot Padgett, Carl Peter Goodrich, Andrea
J. Liu, and James P. Sethna. “Pinning Susceptibility: The Effect of Dilute, Quenched
Disorder on Jamming.” Physical Review Letters. American Physical Society,
2016. https://doi.org/10.1103/physrevlett.116.235501.'
ieee: 'A. L. Graves, S. Nashed, E. Padgett, C. P. Goodrich, A. J. Liu, and J. P.
Sethna, “Pinning susceptibility: The effect of dilute, quenched disorder on jamming,”
Physical Review Letters, vol. 116, no. 23. American Physical Society, 2016.'
ista: 'Graves AL, Nashed S, Padgett E, Goodrich CP, Liu AJ, Sethna JP. 2016. Pinning
susceptibility: The effect of dilute, quenched disorder on jamming. Physical Review
Letters. 116(23), 235501.'
mla: 'Graves, Amy L., et al. “Pinning Susceptibility: The Effect of Dilute, Quenched
Disorder on Jamming.” Physical Review Letters, vol. 116, no. 23, 235501,
American Physical Society, 2016, doi:10.1103/physrevlett.116.235501.'
short: A.L. Graves, S. Nashed, E. Padgett, C.P. Goodrich, A.J. Liu, J.P. Sethna,
Physical Review Letters 116 (2016).
date_created: 2020-04-30T11:40:10Z
date_published: 2016-06-10T00:00:00Z
date_updated: 2021-01-12T08:15:21Z
day: '10'
doi: 10.1103/physrevlett.116.235501
extern: '1'
intvolume: ' 116'
issue: '23'
language:
- iso: eng
month: '06'
oa_version: None
publication: Physical Review Letters
publication_identifier:
issn:
- 0031-9007
- 1079-7114
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
status: public
title: 'Pinning susceptibility: The effect of dilute, quenched disorder on jamming'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 116
year: '2016'
...
---
_id: '7762'
abstract:
- lang: eng
text: Characterizing structural inhomogeneity is an essential step in understanding
the mechanical response of amorphous materials. We introduce a threshold-free
measure based on the field of vectors pointing from the center of each particle
to the centroid of the Voronoi cell in which the particle resides. These vectors
tend to point in toward regions of high free volume and away from regions of low
free volume, reminiscent of sinks and sources in a vector field. We compute the
local divergence of these vectors, where positive values correspond to overpacked
regions and negative values identify underpacked regions within the material.
Distributions of this divergence are nearly Gaussian with zero mean, allowing
for structural characterization using only the moments of the distribution. We
explore how the standard deviation and skewness vary with the packing fraction
for simulations of bidisperse systems and find a kink in these moments that coincides
with the jamming transition.
article_number: '088001 '
article_processing_charge: No
article_type: original
author:
- first_name: Jennifer M.
full_name: Rieser, Jennifer M.
last_name: Rieser
- first_name: Carl Peter
full_name: Goodrich, Carl Peter
id: EB352CD2-F68A-11E9-89C5-A432E6697425
last_name: Goodrich
orcid: 0000-0002-1307-5074
- first_name: Andrea J.
full_name: Liu, Andrea J.
last_name: Liu
- first_name: Douglas J.
full_name: Durian, Douglas J.
last_name: Durian
citation:
ama: 'Rieser JM, Goodrich CP, Liu AJ, Durian DJ. Divergence of Voronoi cell anisotropy
vector: A threshold-free characterization of local structure in amorphous materials.
Physical Review Letters. 2016;116(8). doi:10.1103/physrevlett.116.088001'
apa: 'Rieser, J. M., Goodrich, C. P., Liu, A. J., & Durian, D. J. (2016). Divergence
of Voronoi cell anisotropy vector: A threshold-free characterization of local
structure in amorphous materials. Physical Review Letters. American Physical
Society. https://doi.org/10.1103/physrevlett.116.088001'
chicago: 'Rieser, Jennifer M., Carl Peter Goodrich, Andrea J. Liu, and Douglas J.
Durian. “Divergence of Voronoi Cell Anisotropy Vector: A Threshold-Free Characterization
of Local Structure in Amorphous Materials.” Physical Review Letters. American
Physical Society, 2016. https://doi.org/10.1103/physrevlett.116.088001.'
ieee: 'J. M. Rieser, C. P. Goodrich, A. J. Liu, and D. J. Durian, “Divergence of
Voronoi cell anisotropy vector: A threshold-free characterization of local structure
in amorphous materials,” Physical Review Letters, vol. 116, no. 8. American
Physical Society, 2016.'
ista: 'Rieser JM, Goodrich CP, Liu AJ, Durian DJ. 2016. Divergence of Voronoi cell
anisotropy vector: A threshold-free characterization of local structure in amorphous
materials. Physical Review Letters. 116(8), 088001.'
mla: 'Rieser, Jennifer M., et al. “Divergence of Voronoi Cell Anisotropy Vector:
A Threshold-Free Characterization of Local Structure in Amorphous Materials.”
Physical Review Letters, vol. 116, no. 8, 088001, American Physical Society,
2016, doi:10.1103/physrevlett.116.088001.'
short: J.M. Rieser, C.P. Goodrich, A.J. Liu, D.J. Durian, Physical Review Letters
116 (2016).
date_created: 2020-04-30T11:40:25Z
date_published: 2016-02-23T00:00:00Z
date_updated: 2021-01-12T08:15:22Z
day: '23'
doi: 10.1103/physrevlett.116.088001
extern: '1'
intvolume: ' 116'
issue: '8'
language:
- iso: eng
month: '02'
oa_version: None
publication: Physical Review Letters
publication_identifier:
issn:
- 0031-9007
- 1079-7114
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
status: public
title: 'Divergence of Voronoi cell anisotropy vector: A threshold-free characterization
of local structure in amorphous materials'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 116
year: '2016'
...
---
_id: '7763'
abstract:
- lang: eng
text: An orthogonal wavelet basis is characterized by its approximation order, which
relates to the ability of the basis to represent general smooth functions on a
given scale. It is known, though perhaps not widely known, that there are ways
of exceeding the approximation order, i.e., achieving higher-order error in the
discretized wavelet transform and its inverse. The focus here is on the development
of a practical formulation to accomplish this first for 1D smooth functions, then
for 1D functions with discontinuities and then for multidimensional (here 2D)
functions with discontinuities. It is shown how to transcend both the wavelet
approximation order and the 2D Gibbs phenomenon in representing electromagnetic
fields at discontinuous dielectric interfaces that do not simply follow the wavelet-basis
grid.
article_processing_charge: No
article_type: original
author:
- first_name: Richard
full_name: Lombardini, Richard
last_name: Lombardini
- first_name: Ramiro
full_name: Acevedo, Ramiro
last_name: Acevedo
- first_name: Alexander
full_name: Kuczala, Alexander
last_name: Kuczala
- first_name: Kerry P.
full_name: Keys, Kerry P.
last_name: Keys
- first_name: Carl Peter
full_name: Goodrich, Carl Peter
id: EB352CD2-F68A-11E9-89C5-A432E6697425
last_name: Goodrich
orcid: 0000-0002-1307-5074
- first_name: Bruce R.
full_name: Johnson, Bruce R.
last_name: Johnson
citation:
ama: Lombardini R, Acevedo R, Kuczala A, Keys KP, Goodrich CP, Johnson BR. Higher-order
wavelet reconstruction/differentiation filters and Gibbs phenomena. Journal
of Computational Physics. 2016;305:244-262. doi:10.1016/j.jcp.2015.10.035
apa: Lombardini, R., Acevedo, R., Kuczala, A., Keys, K. P., Goodrich, C. P., &
Johnson, B. R. (2016). Higher-order wavelet reconstruction/differentiation filters
and Gibbs phenomena. Journal of Computational Physics. Elsevier. https://doi.org/10.1016/j.jcp.2015.10.035
chicago: Lombardini, Richard, Ramiro Acevedo, Alexander Kuczala, Kerry P. Keys,
Carl Peter Goodrich, and Bruce R. Johnson. “Higher-Order Wavelet Reconstruction/Differentiation
Filters and Gibbs Phenomena.” Journal of Computational Physics. Elsevier,
2016. https://doi.org/10.1016/j.jcp.2015.10.035.
ieee: R. Lombardini, R. Acevedo, A. Kuczala, K. P. Keys, C. P. Goodrich, and B.
R. Johnson, “Higher-order wavelet reconstruction/differentiation filters and Gibbs
phenomena,” Journal of Computational Physics, vol. 305. Elsevier, pp. 244–262,
2016.
ista: Lombardini R, Acevedo R, Kuczala A, Keys KP, Goodrich CP, Johnson BR. 2016.
Higher-order wavelet reconstruction/differentiation filters and Gibbs phenomena.
Journal of Computational Physics. 305, 244–262.
mla: Lombardini, Richard, et al. “Higher-Order Wavelet Reconstruction/Differentiation
Filters and Gibbs Phenomena.” Journal of Computational Physics, vol. 305,
Elsevier, 2016, pp. 244–62, doi:10.1016/j.jcp.2015.10.035.
short: R. Lombardini, R. Acevedo, A. Kuczala, K.P. Keys, C.P. Goodrich, B.R. Johnson,
Journal of Computational Physics 305 (2016) 244–262.
date_created: 2020-04-30T11:40:41Z
date_published: 2016-01-15T00:00:00Z
date_updated: 2021-01-12T08:15:22Z
day: '15'
doi: 10.1016/j.jcp.2015.10.035
extern: '1'
intvolume: ' 305'
language:
- iso: eng
month: '01'
oa_version: None
page: 244-262
publication: Journal of Computational Physics
publication_identifier:
issn:
- 0021-9991
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: Higher-order wavelet reconstruction/differentiation filters and Gibbs phenomena
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 305
year: '2016'
...
---
_id: '7764'
abstract:
- lang: eng
text: States of self stress, organizations of internal forces in many-body systems
that are in equilibrium with an absence of external forces, can be thought of
as the constitutive building blocks of the elastic response of a material. In
overconstrained disordered packings they have a natural mathematical correspondence
with the zero-energy vibrational modes in underconstrained systems. While substantial
attention in the literature has been paid to diverging length scales associated
with zero- and finite-energy vibrational modes in jammed systems, less is known
about the spatial structure of the states of self stress. In this work we define
a natural way in which a unique state of self stress can be associated with each
bond in a disordered spring network derived from a jammed packing, and then investigate
the spatial structure of these bond-localized states of self stress. This allows
for an understanding of how the elastic properties of a system would change upon
changing the strength or even existence of any bond in the system.
article_processing_charge: No
article_type: original
author:
- first_name: Daniel M.
full_name: Sussman, Daniel M.
last_name: Sussman
- first_name: Carl Peter
full_name: Goodrich, Carl Peter
id: EB352CD2-F68A-11E9-89C5-A432E6697425
last_name: Goodrich
orcid: 0000-0002-1307-5074
- first_name: Andrea J.
full_name: Liu, Andrea J.
last_name: Liu
citation:
ama: Sussman DM, Goodrich CP, Liu AJ. Spatial structure of states of self stress
in jammed systems. Soft Matter. 2016;12(17):3982-3990. doi:10.1039/c6sm00094k
apa: Sussman, D. M., Goodrich, C. P., & Liu, A. J. (2016). Spatial structure
of states of self stress in jammed systems. Soft Matter. Royal Society
of Chemistry. https://doi.org/10.1039/c6sm00094k
chicago: Sussman, Daniel M., Carl Peter Goodrich, and Andrea J. Liu. “Spatial Structure
of States of Self Stress in Jammed Systems.” Soft Matter. Royal Society
of Chemistry, 2016. https://doi.org/10.1039/c6sm00094k.
ieee: D. M. Sussman, C. P. Goodrich, and A. J. Liu, “Spatial structure of states
of self stress in jammed systems,” Soft Matter, vol. 12, no. 17. Royal
Society of Chemistry, pp. 3982–3990, 2016.
ista: Sussman DM, Goodrich CP, Liu AJ. 2016. Spatial structure of states of self
stress in jammed systems. Soft Matter. 12(17), 3982–3990.
mla: Sussman, Daniel M., et al. “Spatial Structure of States of Self Stress in Jammed
Systems.” Soft Matter, vol. 12, no. 17, Royal Society of Chemistry, 2016,
pp. 3982–90, doi:10.1039/c6sm00094k.
short: D.M. Sussman, C.P. Goodrich, A.J. Liu, Soft Matter 12 (2016) 3982–3990.
date_created: 2020-04-30T11:40:56Z
date_published: 2016-03-14T00:00:00Z
date_updated: 2021-01-12T08:15:22Z
day: '14'
doi: 10.1039/c6sm00094k
extern: '1'
intvolume: ' 12'
issue: '17'
language:
- iso: eng
month: '03'
oa_version: None
page: 3982-3990
publication: Soft Matter
publication_identifier:
issn:
- 1744-683X
- 1744-6848
publication_status: published
publisher: Royal Society of Chemistry
quality_controlled: '1'
related_material:
link:
- relation: other
url: https://doi.org/10.1039/c6sm02496c
status: public
title: Spatial structure of states of self stress in jammed systems
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 12
year: '2016'
...
---
_id: '785'
abstract:
- lang: eng
text: High memory contention is generally agreed to be a worst-case scenario for
concurrent data structures. There has been a significant amount of research effort
spent investigating designs which minimize contention, and several programming
techniques have been proposed to mitigate its effects. However, there are currently
few architectural mechanisms to allow scaling contended data structures at high
thread counts. In this paper, we investigate hardware support for scalable contended
data structures. We propose Lease/Release, a simple addition to standard directory-based
MSI cache coherence protocols, allowing participants to lease memory, at the granularity
of cache lines, by delaying coherence messages for a short, bounded period of
time. Our analysis shows that Lease/Release can significantly reduce the overheads
of contention for both non-blocking (lock-free) and lock-based data structure
implementations, while ensuring that no deadlocks are introduced. We validate
Lease/Release empirically on the Graphite multiprocessor simulator, on a range
of data structures, including queue, stack, and priority queue implementations,
as well as on transactional applications. Results show that Lease/Release consistently
improves both throughput and energy usage, by up to 5x, both for lock-free and
lock-based data structure designs.
acknowledgement: We would like to thank Richard Black, Miguel Castro, Dave Dice, Aleksandar
Dragojevic, Maurice Herlihy, Ant Rowstron, Nir Shavit, and Vasileios Trigonakis,
as well as the anonymous reviewers, for helpful suggestions during the development
of this paper.
article_processing_charge: No
author:
- first_name: Syed
full_name: Haider, Syed
last_name: Haider
- first_name: William
full_name: Hasenplaugh, William
last_name: Hasenplaugh
- first_name: Dan-Adrian
full_name: Alistarh, Dan-Adrian
id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
last_name: Alistarh
orcid: 0000-0003-3650-940X
citation:
ama: 'Haider S, Hasenplaugh W, Alistarh D-A. Lease/Release: Architectural support
for scaling contended data structures. In: Vol 12-16-March-2016. ACM; 2016. doi:10.1145/2851141.2851155'
apa: 'Haider, S., Hasenplaugh, W., & Alistarh, D.-A. (2016). Lease/Release:
Architectural support for scaling contended data structures (Vol. 12-16-March-2016).
Presented at the PPoPP: Principles and Practice of Parallel Pogramming, ACM. https://doi.org/10.1145/2851141.2851155'
chicago: 'Haider, Syed, William Hasenplaugh, and Dan-Adrian Alistarh. “Lease/Release:
Architectural Support for Scaling Contended Data Structures,” Vol. 12-16-March-2016.
ACM, 2016. https://doi.org/10.1145/2851141.2851155.'
ieee: 'S. Haider, W. Hasenplaugh, and D.-A. Alistarh, “Lease/Release: Architectural
support for scaling contended data structures,” presented at the PPoPP: Principles
and Practice of Parallel Pogramming, 2016, vol. 12-16-March-2016.'
ista: 'Haider S, Hasenplaugh W, Alistarh D-A. 2016. Lease/Release: Architectural
support for scaling contended data structures. PPoPP: Principles and Practice
of Parallel Pogramming vol. 12-16-March-2016.'
mla: 'Haider, Syed, et al. Lease/Release: Architectural Support for Scaling Contended
Data Structures. Vol. 12-16-March-2016, ACM, 2016, doi:10.1145/2851141.2851155.'
short: S. Haider, W. Hasenplaugh, D.-A. Alistarh, in:, ACM, 2016.
conference:
name: 'PPoPP: Principles and Practice of Parallel Pogramming'
date_created: 2018-12-11T11:48:29Z
date_published: 2016-02-27T00:00:00Z
date_updated: 2022-03-18T12:56:29Z
day: '27'
doi: 10.1145/2851141.2851155
extern: '1'
language:
- iso: eng
month: '02'
oa_version: None
publication_status: published
publisher: ACM
publist_id: '6871'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Lease/Release: Architectural support for scaling contended data structures'
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 12-16-March-2016
year: '2016'
...
---
_id: '786'
abstract:
- lang: eng
text: Lock-free concurrent algorithms guarantee that some concurrent operation will
always make progress in a finite number of steps. Yet programmers prefer to treat
concurrent code as if it were wait-free, guaranteeing that all operations always
make progress. Unfortunately, designing wait-free algorithms is generally a very
complex task, and the resulting algorithms are not always efficient. Although
obtaining efficient wait-free algorithms has been a long-time goal for the theory
community, most nonblocking commercial code is only lock-free. This article suggests
a simple solution to this problem.We show that for a large class of lock-free
algorithms, under scheduling conditions that approximate those found in commercial
hardware architectures, lock-free algorithms behave as if they are wait-free.
In other words, programmers can continue to design simple lock-free algorithms
instead of complex wait-free ones, and in practice, they will get wait-free progress.
Our main contribution is a new way of analyzing a general class of lock-free algorithms
under a stochastic scheduler. Our analysis relates the individual performance
of processes to the global performance of the system using Markov chain lifting
between a complex per-process chain and a simpler system progress chain. We show
that lock-free algorithms are not only wait-free with probability 1 but that in
fact a general subset of lock-free algorithms can be closely bounded in terms
of the average number of steps required until an operation completes. To the best
of our knowledge, this is the first attempt to analyze progress conditions, typically
stated in relation to a worst-case adversary, in a stochastic model capturing
their expected asymptotic behavior.
acknowledgement: Part of this work was performed while the first author was a postdoctoral
associate at MIT CSAIL, where he was supported by the SNF Postdoctoral Fellows Program,
NSF grant CCF-1217921, DoE ASCR grant ER26116/DE-SC0008923, and by grants from the
Oracle and Intel corporations. The second author was supported in part by ISF grant
1696/14. The third author was supported in part by NSF grants CCF-1217921, CCF-1301926,
IIS-1447786, and CCF-1561807, and the U.S. Department of Energy under grant DE-SC0008923,
and by equipment grants from Intel Corporation.
article_processing_charge: No
arxiv: 1
author:
- first_name: Dan-Adrian
full_name: Alistarh, Dan-Adrian
id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
last_name: Alistarh
orcid: 0000-0003-3650-940X
- first_name: Keren
full_name: Censor Hillel, Keren
last_name: Censor Hillel
- first_name: Nir
full_name: Shavit, Nir
last_name: Shavit
citation:
ama: Alistarh D-A, Censor Hillel K, Shavit N. Are lock free concurrent algorithms
practically wait free . Journal of the ACM. 2016;63(4). doi:10.1145/2903136
apa: Alistarh, D.-A., Censor Hillel, K., & Shavit, N. (2016). Are lock free
concurrent algorithms practically wait free . Journal of the ACM. ACM.
https://doi.org/10.1145/2903136
chicago: Alistarh, Dan-Adrian, Keren Censor Hillel, and Nir Shavit. “Are Lock Free
Concurrent Algorithms Practically Wait Free .” Journal of the ACM. ACM,
2016. https://doi.org/10.1145/2903136.
ieee: D.-A. Alistarh, K. Censor Hillel, and N. Shavit, “Are lock free concurrent
algorithms practically wait free ,” Journal of the ACM, vol. 63, no. 4.
ACM, 2016.
ista: Alistarh D-A, Censor Hillel K, Shavit N. 2016. Are lock free concurrent algorithms
practically wait free . Journal of the ACM. 63(4).
mla: Alistarh, Dan-Adrian, et al. “Are Lock Free Concurrent Algorithms Practically
Wait Free .” Journal of the ACM, vol. 63, no. 4, ACM, 2016, doi:10.1145/2903136.
short: D.-A. Alistarh, K. Censor Hillel, N. Shavit, Journal of the ACM 63 (2016).
date_created: 2018-12-11T11:48:29Z
date_published: 2016-09-01T00:00:00Z
date_updated: 2023-02-23T13:19:04Z
day: '01'
doi: 10.1145/2903136
extern: '1'
external_id:
arxiv:
- '1311.3200'
intvolume: ' 63'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1311.3200
month: '09'
oa: 1
oa_version: Preprint
publication: Journal of the ACM
publication_status: published
publisher: ACM
publist_id: '6870'
quality_controlled: '1'
status: public
title: 'Are lock free concurrent algorithms practically wait free '
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 63
year: '2016'
...
---
_id: '8020'
abstract:
- lang: eng
text: Balance of cortical excitation and inhibition (EI) is thought to be disrupted
in several neuropsychiatric conditions, yet it is not clear how it is maintained
in the healthy human brain. When EI balance is disturbed during learning and memory
in animal models, it can be restabilized via formation of inhibitory replicas
of newly formed excitatory connections. Here we assess evidence for such selective
inhibitory rebalancing in humans. Using fMRI repetition suppression we measure
newly formed cortical associations in the human brain. We show that expression
of these associations reduces over time despite persistence in behavior, consistent
with inhibitory rebalancing. To test this, we modulated excitation/inhibition
balance with transcranial direct current stimulation (tDCS). Using ultra-high-field
(7T) MRI and spectroscopy, we show that reducing GABA allows cortical associations
to be re-expressed. This suggests that in humans associative memories are stored
in balanced excitatory-inhibitory ensembles that lie dormant unless latent inhibitory
connections are unmasked.
article_processing_charge: No
article_type: original
author:
- first_name: H.C.
full_name: Barron, H.C.
last_name: Barron
- first_name: Tim P
full_name: Vogels, Tim P
id: CB6FF8D2-008F-11EA-8E08-2637E6697425
last_name: Vogels
orcid: 0000-0003-3295-6181
- first_name: U.E.
full_name: Emir, U.E.
last_name: Emir
- first_name: T.R.
full_name: Makin, T.R.
last_name: Makin
- first_name: J.
full_name: O’Shea, J.
last_name: O’Shea
- first_name: S.
full_name: Clare, S.
last_name: Clare
- first_name: S.
full_name: Jbabdi, S.
last_name: Jbabdi
- first_name: R.J.
full_name: Dolan, R.J.
last_name: Dolan
- first_name: T.E.J.
full_name: Behrens, T.E.J.
last_name: Behrens
citation:
ama: Barron HC, Vogels TP, Emir UE, et al. Unmasking latent inhibitory connections
in human cortex to reveal dormant cortical memories. Neuron. 2016;90(1):191-203.
doi:10.1016/j.neuron.2016.02.031
apa: Barron, H. C., Vogels, T. P., Emir, U. E., Makin, T. R., O’Shea, J., Clare,
S., … Behrens, T. E. J. (2016). Unmasking latent inhibitory connections in human
cortex to reveal dormant cortical memories. Neuron. Elsevier. https://doi.org/10.1016/j.neuron.2016.02.031
chicago: Barron, H.C., Tim P Vogels, U.E. Emir, T.R. Makin, J. O’Shea, S. Clare,
S. Jbabdi, R.J. Dolan, and T.E.J. Behrens. “Unmasking Latent Inhibitory Connections
in Human Cortex to Reveal Dormant Cortical Memories.” Neuron. Elsevier,
2016. https://doi.org/10.1016/j.neuron.2016.02.031.
ieee: H. C. Barron et al., “Unmasking latent inhibitory connections in human
cortex to reveal dormant cortical memories,” Neuron, vol. 90, no. 1. Elsevier,
pp. 191–203, 2016.
ista: Barron HC, Vogels TP, Emir UE, Makin TR, O’Shea J, Clare S, Jbabdi S, Dolan
RJ, Behrens TEJ. 2016. Unmasking latent inhibitory connections in human cortex
to reveal dormant cortical memories. Neuron. 90(1), 191–203.
mla: Barron, H. C., et al. “Unmasking Latent Inhibitory Connections in Human Cortex
to Reveal Dormant Cortical Memories.” Neuron, vol. 90, no. 1, Elsevier,
2016, pp. 191–203, doi:10.1016/j.neuron.2016.02.031.
short: H.C. Barron, T.P. Vogels, U.E. Emir, T.R. Makin, J. O’Shea, S. Clare, S.
Jbabdi, R.J. Dolan, T.E.J. Behrens, Neuron 90 (2016) 191–203.
date_created: 2020-06-25T13:05:33Z
date_published: 2016-04-06T00:00:00Z
date_updated: 2021-01-12T08:16:34Z
day: '06'
ddc:
- '570'
doi: 10.1016/j.neuron.2016.02.031
extern: '1'
external_id:
pmid:
- '26996082'
file:
- access_level: open_access
checksum: 9ce7a1c64986dce0435c070285a7ef9b
content_type: application/pdf
creator: cziletti
date_created: 2020-07-09T09:57:04Z
date_updated: 2020-07-14T12:48:08Z
file_id: '8104'
file_name: 2016_Neuron_Barron.pdf
file_size: 5334136
relation: main_file
file_date_updated: 2020-07-14T12:48:08Z
has_accepted_license: '1'
intvolume: ' 90'
issue: '1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '04'
oa: 1
oa_version: Published Version
page: 191-203
pmid: 1
publication: Neuron
publication_identifier:
issn:
- 0896-6273
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: Unmasking latent inhibitory connections in human cortex to reveal dormant cortical
memories
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: D865714E-FA4E-11E9-B85B-F5C5E5697425
volume: 90
year: '2016'
...
---
_id: '8094'
abstract:
- lang: eng
text: 'With the accelerated development of robot technologies, optimal control becomes
one of the central themes of research. In traditional approaches, the controller,
by its internal functionality, finds appropriate actions on the basis of the history
of sensor values, guided by the goals, intentions, objectives, learning schemes,
and so forth. The idea is that the controller controls the world---the body plus
its environment---as reliably as possible. This paper focuses on new lines of
self-organization for developmental robotics. We apply the recently developed
differential extrinsic synaptic plasticity to a muscle-tendon driven arm-shoulder
system from the Myorobotics toolkit. In the experiments, we observe a vast variety
of self-organized behavior patterns: when left alone, the arm realizes pseudo-random
sequences of different poses. By applying physical forces, the system can be entrained
into definite motion patterns like wiping a table. Most interestingly, after attaching
an object, the controller gets in a functional resonance with the object''s internal
dynamics, starting to shake spontaneously bottles half-filled with water or sensitively
driving an attached pendulum into a circular mode. When attached to the crank
of a wheel the neural system independently discovers how to rotate it. In this
way, the robot discovers affordances of objects its body is interacting with.'
article_processing_charge: No
author:
- first_name: Georg S
full_name: Martius, Georg S
id: 3A276B68-F248-11E8-B48F-1D18A9856A87
last_name: Martius
- first_name: Rafael
full_name: Hostettler, Rafael
last_name: Hostettler
- first_name: Alois
full_name: Knoll, Alois
last_name: Knoll
- first_name: Ralf
full_name: Der, Ralf
last_name: Der
citation:
ama: 'Martius GS, Hostettler R, Knoll A, Der R. Self-organized control of an tendon
driven arm by differential extrinsic plasticity. In: Proceedings of the Artificial
Life Conference 2016. Vol 28. MIT Press; 2016:142-143. doi:10.7551/978-0-262-33936-0-ch029'
apa: 'Martius, G. S., Hostettler, R., Knoll, A., & Der, R. (2016). Self-organized
control of an tendon driven arm by differential extrinsic plasticity. In Proceedings
of the Artificial Life Conference 2016 (Vol. 28, pp. 142–143). Cancun, Mexico:
MIT Press. https://doi.org/10.7551/978-0-262-33936-0-ch029'
chicago: Martius, Georg S, Rafael Hostettler, Alois Knoll, and Ralf Der. “Self-Organized
Control of an Tendon Driven Arm by Differential Extrinsic Plasticity.” In Proceedings
of the Artificial Life Conference 2016, 28:142–43. MIT Press, 2016. https://doi.org/10.7551/978-0-262-33936-0-ch029.
ieee: G. S. Martius, R. Hostettler, A. Knoll, and R. Der, “Self-organized control
of an tendon driven arm by differential extrinsic plasticity,” in Proceedings
of the Artificial Life Conference 2016, Cancun, Mexico, 2016, vol. 28, pp.
142–143.
ista: 'Martius GS, Hostettler R, Knoll A, Der R. 2016. Self-organized control of
an tendon driven arm by differential extrinsic plasticity. Proceedings of the
Artificial Life Conference 2016. ALIFE 2016: 15th International Conference on
the Synthesis and Simulation of Living Systems vol. 28, 142–143.'
mla: Martius, Georg S., et al. “Self-Organized Control of an Tendon Driven Arm by
Differential Extrinsic Plasticity.” Proceedings of the Artificial Life Conference
2016, vol. 28, MIT Press, 2016, pp. 142–43, doi:10.7551/978-0-262-33936-0-ch029.
short: G.S. Martius, R. Hostettler, A. Knoll, R. Der, in:, Proceedings of the Artificial
Life Conference 2016, MIT Press, 2016, pp. 142–143.
conference:
end_date: 2016-07-08
location: Cancun, Mexico
name: 'ALIFE 2016: 15th International Conference on the Synthesis and Simulation
of Living Systems'
start_date: 2016-07-04
date_created: 2020-07-05T22:00:47Z
date_published: 2016-09-01T00:00:00Z
date_updated: 2021-01-12T08:16:53Z
day: '01'
ddc:
- '610'
department:
- _id: ChLa
- _id: GaTk
doi: 10.7551/978-0-262-33936-0-ch029
ec_funded: 1
file:
- access_level: open_access
checksum: cff63e7a4b8ac466ba51a9c84153a940
content_type: application/pdf
creator: cziletti
date_created: 2020-07-06T12:59:09Z
date_updated: 2020-07-14T12:48:09Z
file_id: '8096'
file_name: 2016_ProcALIFE_Martius.pdf
file_size: 678670
relation: main_file
file_date_updated: 2020-07-14T12:48:09Z
has_accepted_license: '1'
intvolume: ' 28'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: 142-143
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: Proceedings of the Artificial Life Conference 2016
publication_identifier:
isbn:
- '9780262339360'
publication_status: published
publisher: MIT Press
quality_controlled: '1'
scopus_import: 1
status: public
title: Self-organized control of an tendon driven arm by differential extrinsic plasticity
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: D865714E-FA4E-11E9-B85B-F5C5E5697425
volume: 28
year: '2016'
...
---
_id: '8128'
abstract:
- lang: eng
text: The stimulus selectivity of synaptic currents in cortical neurons often shows
a co-tuning of excitation and inhibition, but the mechanisms that underlie the
emergence and plasticity of this co-tuning are not fully understood. Using a computational
model, we show that an interaction of excitatory and inhibitory synaptic plasticity
reproduces both the developmental and – when combined with a disinhibitory gate
– the adult plasticity of excitatory and inhibitory receptive fields in auditory
cortex. The co-tuning arises from inhibitory plasticity that balances excitation
and inhibition, while excitatory stimulus selectivity can result from two different
mechanisms. Inhibitory inputs with a broad stimulus tuning introduce a sliding
threshold as in Bienenstock-Cooper-Munro rules, introducing an excitatory stimulus
selectivity at the cost of a broader inhibitory receptive field. Alternatively,
input asymmetries can be amplified by synaptic competition. The latter leaves
any receptive field plasticity transient, a prediction we verify in recordings
in auditory cortex.
article_processing_charge: No
author:
- first_name: Claudia
full_name: Clopath, Claudia
last_name: Clopath
- first_name: Tim P
full_name: Vogels, Tim P
id: CB6FF8D2-008F-11EA-8E08-2637E6697425
last_name: Vogels
orcid: 0000-0003-3295-6181
- first_name: Robert C.
full_name: Froemke, Robert C.
last_name: Froemke
- first_name: Henning
full_name: Sprekeler, Henning
last_name: Sprekeler
citation:
ama: Clopath C, Vogels TP, Froemke RC, Sprekeler H. Receptive field formation by
interacting excitatory and inhibitory synaptic plasticity. bioRxiv. 2016.
apa: Clopath, C., Vogels, T. P., Froemke, R. C., & Sprekeler, H. (2016). Receptive
field formation by interacting excitatory and inhibitory synaptic plasticity.
bioRxiv. Cold Spring Harbor Laboratory.
chicago: Clopath, Claudia, Tim P Vogels, Robert C. Froemke, and Henning Sprekeler.
“Receptive Field Formation by Interacting Excitatory and Inhibitory Synaptic Plasticity.”
BioRxiv. Cold Spring Harbor Laboratory, 2016.
ieee: C. Clopath, T. P. Vogels, R. C. Froemke, and H. Sprekeler, “Receptive field
formation by interacting excitatory and inhibitory synaptic plasticity,” bioRxiv.
Cold Spring Harbor Laboratory, 2016.
ista: Clopath C, Vogels TP, Froemke RC, Sprekeler H. 2016. Receptive field formation
by interacting excitatory and inhibitory synaptic plasticity. bioRxiv, .
mla: Clopath, Claudia, et al. “Receptive Field Formation by Interacting Excitatory
and Inhibitory Synaptic Plasticity.” BioRxiv, Cold Spring Harbor Laboratory,
2016.
short: C. Clopath, T.P. Vogels, R.C. Froemke, H. Sprekeler, BioRxiv (2016).
date_created: 2020-07-16T12:26:55Z
date_published: 2016-07-29T00:00:00Z
date_updated: 2021-01-12T08:17:02Z
day: '29'
extern: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: 'https://doi.org/10.1101/066589 '
month: '07'
oa: 1
oa_version: Preprint
page: '43'
publication: bioRxiv
publication_status: published
publisher: Cold Spring Harbor Laboratory
status: public
title: Receptive field formation by interacting excitatory and inhibitory synaptic
plasticity
type: preprint
user_id: D865714E-FA4E-11E9-B85B-F5C5E5697425
year: '2016'
...
---
_id: '813'
abstract:
- lang: eng
text: The Gag polyprotein of retroviruses drives immature virus assembly by forming
hexameric protein lattices. The assembly is primarily mediated by protein-protein
interactions between capsid (CA) domains and by interactions between nucleocapsid
(NC) domains and RNA. Specific interactions between NC and the viral RNA are required
for genome packaging. Previously reported cryoelectron microscopy analysis of
immature Mason-Pfizer monkey virus (M-PMV) particles suggested that a basic region
(residues RKK) in CA may serve as an additional binding site for nucleic acids.
Here, we have introduced mutations into the RKK region in both bacterial and proviral
M-PMV vectors and have assessed their impact on M-PMV assembly, structure, RNA
binding, budding/release, nuclear trafficking, and infectivity using in vitro
and in vivo systems. Our data indicate that the RKK region binds and structures
nucleic acid that serves to promote virus particle assembly in the cytoplasm.
Moreover, the RKK region appears to be important for recruitment of viral genomic
RNA into Gag particles, and this function could be linked to changes in nuclear
trafficking. Together these observations suggest that in M-PMV, direct interactions
between CA and nucleic acid play important functions in the late stages of the
viral life cycle.
acknowledgement: |-
Work in the laboratory of John A. G. Briggs was funded by Deutsche
Forschungsgemeinschaft (DFG) (BR 3635/2-1). This work, including the
efforts of Tomas Ruml, was funded by the Grant Agency of the Czech
Republic (14-15326S) and the Czech Ministry of Education (NPU I sus-
tainability projects LO1302 and LO1304).
author:
- first_name: Tibor
full_name: Füzik, Tibor
last_name: Füzik
- first_name: Růžena
full_name: ' Píchalová, Růžena'
last_name: Píchalová
- first_name: Florian
full_name: Florian Schur
id: 48AD8942-F248-11E8-B48F-1D18A9856A87
last_name: Schur
orcid: 0000-0003-4790-8078
- first_name: Karolína
full_name: Strohalmová, Karolína
last_name: Strohalmová
- first_name: Ivana
full_name: Křížová, Ivana
last_name: Křížová
- first_name: Romana
full_name: Hadravová, Romana
last_name: Hadravová
- first_name: Michaela
full_name: Rumlová, Michaela
last_name: Rumlová
- first_name: John
full_name: Briggs, John A
last_name: Briggs
- first_name: Pavel
full_name: Ulbrich, Pavel
last_name: Ulbrich
- first_name: Tomáš
full_name: Ruml, Tomáš
last_name: Ruml
citation:
ama: Füzik T, Píchalová R, Schur FK, et al. Nucleic acid binding by Mason-Pfizer
monkey virus CA promotes virus assembly and genome packaging. Journal of Virology.
2016;90(9):4593-4603. doi:10.1128/JVI.03197-15
apa: Füzik, T., Píchalová, R., Schur, F. K., Strohalmová, K., Křížová, I., Hadravová,
R., … Ruml, T. (2016). Nucleic acid binding by Mason-Pfizer monkey virus CA promotes
virus assembly and genome packaging. Journal of Virology. ASM. https://doi.org/10.1128/JVI.03197-15
chicago: Füzik, Tibor, Růžena Píchalová, Florian KM Schur, Karolína Strohalmová,
Ivana Křížová, Romana Hadravová, Michaela Rumlová, John Briggs, Pavel Ulbrich,
and Tomáš Ruml. “Nucleic Acid Binding by Mason-Pfizer Monkey Virus CA Promotes
Virus Assembly and Genome Packaging.” Journal of Virology. ASM, 2016. https://doi.org/10.1128/JVI.03197-15.
ieee: T. Füzik et al., “Nucleic acid binding by Mason-Pfizer monkey virus
CA promotes virus assembly and genome packaging,” Journal of Virology,
vol. 90, no. 9. ASM, pp. 4593–4603, 2016.
ista: Füzik T, Píchalová R, Schur FK, Strohalmová K, Křížová I, Hadravová R, Rumlová
M, Briggs J, Ulbrich P, Ruml T. 2016. Nucleic acid binding by Mason-Pfizer monkey
virus CA promotes virus assembly and genome packaging. Journal of Virology. 90(9),
4593–4603.
mla: Füzik, Tibor, et al. “Nucleic Acid Binding by Mason-Pfizer Monkey Virus CA
Promotes Virus Assembly and Genome Packaging.” Journal of Virology, vol.
90, no. 9, ASM, 2016, pp. 4593–603, doi:10.1128/JVI.03197-15.
short: T. Füzik, R. Píchalová, F.K. Schur, K. Strohalmová, I. Křížová, R. Hadravová,
M. Rumlová, J. Briggs, P. Ulbrich, T. Ruml, Journal of Virology 90 (2016) 4593–4603.
date_created: 2018-12-11T11:48:38Z
date_published: 2016-05-01T00:00:00Z
date_updated: 2021-01-12T08:17:03Z
day: '01'
doi: 10.1128/JVI.03197-15
extern: 1
intvolume: ' 90'
issue: '9'
month: '05'
page: 4593 - 4603
publication: Journal of Virology
publication_status: published
publisher: ASM
publist_id: '6835'
quality_controlled: 0
status: public
title: Nucleic acid binding by Mason-Pfizer monkey virus CA promotes virus assembly
and genome packaging
type: journal_article
volume: 90
year: '2016'
...
---
_id: '816'
abstract:
- lang: eng
text: Immature HIV-1 assembles at and buds from the plasma membrane before proteolytic
cleavage of the viral Gag polyprotein induces structural maturation. Maturation
can be blocked by maturation inhibitors (MIs), thereby abolishing infectivity.
The CA (capsid) and SP1 (spacer peptide 1) region of Gag is the key regulator
of assembly and maturation and is the target of MIs.We applied optimized cryo-electron
tomography and subtomogram averaging to resolve this region within assembled immature
HIV-1 particles at 3.9 angstrom resolution and built an atomic model. The structure
reveals a network of intra- And intermolecular interactions mediating immature
HIV-1 assembly. The proteolytic cleavage site between CA and SP1 is inaccessible
to protease.We suggest that MIs prevent CA-SP1 cleavage by stabilizing the structure,
and MI resistance develops by destabilizing CA-SP1.
acknowledgement: The authors thank B. Glass for preparation of the immature HIV-1
(D25A) sample; J. Plitzko and D. Tegunov for providing the K2Align software; and
S. Mattei, N. Hoffman, F. Thommen, A. Sonnen, and S. Dodonova for technical assistance
and/or discussion. This study was supported by Deutsche Forschungsgemeinschaft grants
BR 3635/2-1 (to J.A.G.B.) and KR 906/7-1 (to H.-G.K.). The Briggs laboratory acknowledges
financial support from the European Molecular Biology Laboratory (EMBL) and from
the Chica und Heinz Schaller Stiftung. W.W. was supported by a European Molecular
Biology Organization Long-Term Fellowship (ALTF 748-2014). A.J.J. acknowledges support
by the EMBL Interdisciplinary Postdoc Program under the Marie Curie Action COFUND
(PCOFUND-GA-2008-229597) and by the Joachim Herz Stiftung. This study was technically
supported by the EMBL information technology services unit and the EMBL Proteomics
Core Facility. F.K.M.S., M.O., H.-G.K., and J.A.G.B. designed the experiments, with
J.M.K. assisting in the design of those involving mass spectrometry. F.K.M.S. and
M.O. prepared samples. W.J.H.H. implemented tomography acquisition schemes. F.K.M.S.
and W.J.H.H. acquired the data. F.K.M.S. and W.W. processed images. F.K.M.S., A.J.J.,
and C.S. refined the model. F.K.M.S., M.O., and J.A.G.B. analyzed the data. F.K.M.S.
and J.A.G.B. wrote the manuscript with support from all authors. Representative
tomograms and the final electron microscopy structures have been deposited in the
Electron Microscopy Data Bank with accession numbers EMD-4015, EMD-4016, EMD-4017,
EMD-4018, EMD-4019, and EMD-4020. The refined HIV-1 CA-SP1 model has been deposited
in the Protein Data Bank with accession number 5L93.
author:
- first_name: Florian
full_name: Florian Schur
id: 48AD8942-F248-11E8-B48F-1D18A9856A87
last_name: Schur
orcid: 0000-0003-4790-8078
- first_name: Martin
full_name: Martin Obr
id: 4741CA5A-F248-11E8-B48F-1D18A9856A87
last_name: Obr
- first_name: Wim
full_name: Hagen, Wim J
last_name: Hagen
- first_name: William
full_name: Wan, William
last_name: Wan
- first_name: Arjen
full_name: Jakobi, Arjen J
last_name: Jakobi
- first_name: Joanna
full_name: Kirkpatrick, Joanna M
last_name: Kirkpatrick
- first_name: Carsten
full_name: Sachse, Carsten
last_name: Sachse
- first_name: Hans
full_name: Kraüsslich, Hans Georg
last_name: Kraüsslich
- first_name: John
full_name: Briggs, John A
last_name: Briggs
citation:
ama: Schur FK, Obr M, Hagen W, et al. An atomic model of HIV-1 capsid-SP1 reveals
structures regulating assembly and maturation. Science. 2016;353(6298):506-508.
doi:10.1126/science.aaf9620
apa: Schur, F. K., Obr, M., Hagen, W., Wan, W., Jakobi, A., Kirkpatrick, J., … Briggs,
J. (2016). An atomic model of HIV-1 capsid-SP1 reveals structures regulating assembly
and maturation. Science. American Association for the Advancement of Science.
https://doi.org/10.1126/science.aaf9620
chicago: Schur, Florian KM, Martin Obr, Wim Hagen, William Wan, Arjen Jakobi, Joanna
Kirkpatrick, Carsten Sachse, Hans Kraüsslich, and John Briggs. “An Atomic Model
of HIV-1 Capsid-SP1 Reveals Structures Regulating Assembly and Maturation.” Science.
American Association for the Advancement of Science, 2016. https://doi.org/10.1126/science.aaf9620.
ieee: F. K. Schur et al., “An atomic model of HIV-1 capsid-SP1 reveals structures
regulating assembly and maturation,” Science, vol. 353, no. 6298. American
Association for the Advancement of Science, pp. 506–508, 2016.
ista: Schur FK, Obr M, Hagen W, Wan W, Jakobi A, Kirkpatrick J, Sachse C, Kraüsslich
H, Briggs J. 2016. An atomic model of HIV-1 capsid-SP1 reveals structures regulating
assembly and maturation. Science. 353(6298), 506–508.
mla: Schur, Florian KM, et al. “An Atomic Model of HIV-1 Capsid-SP1 Reveals Structures
Regulating Assembly and Maturation.” Science, vol. 353, no. 6298, American
Association for the Advancement of Science, 2016, pp. 506–08, doi:10.1126/science.aaf9620.
short: F.K. Schur, M. Obr, W. Hagen, W. Wan, A. Jakobi, J. Kirkpatrick, C. Sachse,
H. Kraüsslich, J. Briggs, Science 353 (2016) 506–508.
date_created: 2018-12-11T11:48:39Z
date_published: 2016-07-29T00:00:00Z
date_updated: 2021-01-12T08:17:12Z
day: '29'
doi: 10.1126/science.aaf9620
extern: 1
intvolume: ' 353'
issue: '6298'
month: '07'
page: 506 - 508
publication: Science
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '6834'
quality_controlled: 0
status: public
title: An atomic model of HIV-1 capsid-SP1 reveals structures regulating assembly
and maturation
type: journal_article
volume: 353
year: '2016'
...
---
_id: '1479'
abstract:
- lang: eng
text: "Most entropy notions H(.) like Shannon or min-entropy satisfy a chain rule
stating that for random variables X,Z, and A we have H(X|Z,A)≥H(X|Z)−|A|. That
is, by conditioning on A the entropy of X can decrease by at most the bitlength
|A| of A. Such chain rules are known to hold for some computational entropy notions
like Yao’s and unpredictability-entropy. For HILL entropy, the computational analogue
of min-entropy, the chain rule is of special interest and has found many applications,
including leakage-resilient cryptography, deterministic encryption, and memory
delegation. These applications rely on restricted special cases of the chain rule.
Whether the chain rule for conditional HILL entropy holds in general was an open
problem for which we give a strong negative answer: we construct joint distributions
(X,Z,A), where A is a distribution over a single bit, such that the HILL entropy
H HILL (X|Z) is large but H HILL (X|Z,A) is basically zero.\r\n\r\nOur counterexample
just makes the minimal assumption that NP⊈P/poly. Under the stronger assumption
that injective one-way function exist, we can make all the distributions efficiently
samplable.\r\n\r\nFinally, we show that some more sophisticated cryptographic
objects like lossy functions can be used to sample a distribution constituting
a counterexample to the chain rule making only a single invocation to the underlying
object."
acknowledgement: "This work was partly funded by the European Research Council under
ERC Starting Grant 259668-PSPC and ERC Advanced Grant 321310-PERCY.\r\n"
author:
- first_name: Stephan
full_name: Krenn, Stephan
id: 329FCCF0-F248-11E8-B48F-1D18A9856A87
last_name: Krenn
orcid: 0000-0003-2835-9093
- first_name: Krzysztof Z
full_name: Pietrzak, Krzysztof Z
id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
last_name: Pietrzak
orcid: 0000-0002-9139-1654
- first_name: Akshay
full_name: Wadia, Akshay
last_name: Wadia
- first_name: Daniel
full_name: Wichs, Daniel
last_name: Wichs
citation:
ama: Krenn S, Pietrzak KZ, Wadia A, Wichs D. A counterexample to the chain rule
for conditional HILL entropy. Computational Complexity. 2016;25(3):567-605.
doi:10.1007/s00037-015-0120-9
apa: Krenn, S., Pietrzak, K. Z., Wadia, A., & Wichs, D. (2016). A counterexample
to the chain rule for conditional HILL entropy. Computational Complexity.
Springer. https://doi.org/10.1007/s00037-015-0120-9
chicago: Krenn, Stephan, Krzysztof Z Pietrzak, Akshay Wadia, and Daniel Wichs. “A
Counterexample to the Chain Rule for Conditional HILL Entropy.” Computational
Complexity. Springer, 2016. https://doi.org/10.1007/s00037-015-0120-9.
ieee: S. Krenn, K. Z. Pietrzak, A. Wadia, and D. Wichs, “A counterexample to the
chain rule for conditional HILL entropy,” Computational Complexity, vol.
25, no. 3. Springer, pp. 567–605, 2016.
ista: Krenn S, Pietrzak KZ, Wadia A, Wichs D. 2016. A counterexample to the chain
rule for conditional HILL entropy. Computational Complexity. 25(3), 567–605.
mla: Krenn, Stephan, et al. “A Counterexample to the Chain Rule for Conditional
HILL Entropy.” Computational Complexity, vol. 25, no. 3, Springer, 2016,
pp. 567–605, doi:10.1007/s00037-015-0120-9.
short: S. Krenn, K.Z. Pietrzak, A. Wadia, D. Wichs, Computational Complexity 25
(2016) 567–605.
date_created: 2018-12-11T11:52:16Z
date_published: 2016-09-01T00:00:00Z
date_updated: 2023-02-23T11:05:09Z
day: '01'
ddc:
- '004'
department:
- _id: KrPi
doi: 10.1007/s00037-015-0120-9
ec_funded: 1
file:
- access_level: open_access
checksum: 7659296174fa75f5f0364f31f46f4bcf
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:13:29Z
date_updated: 2020-07-14T12:44:56Z
file_id: '5012'
file_name: IST-2017-766-v1+1_678.pdf
file_size: 483258
relation: main_file
file_date_updated: 2020-07-14T12:44:56Z
has_accepted_license: '1'
intvolume: ' 25'
issue: '3'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Submitted Version
page: 567 - 605
project:
- _id: 258C570E-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '259668'
name: Provable Security for Physical Cryptography
publication: Computational Complexity
publication_status: published
publisher: Springer
publist_id: '5715'
pubrep_id: '766'
quality_controlled: '1'
related_material:
record:
- id: '2940'
relation: earlier_version
status: public
scopus_import: 1
status: public
title: A counterexample to the chain rule for conditional HILL entropy
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 25
year: '2016'
...
---
_id: '1480'
abstract:
- lang: eng
text: 'Exponential varieties arise from exponential families in statistics. These
real algebraic varieties have strong positivity and convexity properties, familiar
from toric varieties and their moment maps. Among them are varieties of inverses
of symmetric matrices satisfying linear constraints. This class includes Gaussian
graphical models. We develop a general theory of exponential varieties. These
are derived from hyperbolic polynomials and their integral representations. We
compare the multidegrees and ML degrees of the gradient map for hyperbolic polynomials. '
author:
- first_name: Mateusz
full_name: Michałek, Mateusz
last_name: Michałek
- first_name: Bernd
full_name: Sturmfels, Bernd
last_name: Sturmfels
- first_name: Caroline
full_name: Uhler, Caroline
id: 49ADD78E-F248-11E8-B48F-1D18A9856A87
last_name: Uhler
orcid: 0000-0002-7008-0216
- first_name: Piotr
full_name: Zwiernik, Piotr
last_name: Zwiernik
citation:
ama: Michałek M, Sturmfels B, Uhler C, Zwiernik P. Exponential varieties. Proceedings
of the London Mathematical Society. 2016;112(1):27-56. doi:10.1112/plms/pdv066
apa: Michałek, M., Sturmfels, B., Uhler, C., & Zwiernik, P. (2016). Exponential
varieties. Proceedings of the London Mathematical Society. Oxford University
Press. https://doi.org/10.1112/plms/pdv066
chicago: Michałek, Mateusz, Bernd Sturmfels, Caroline Uhler, and Piotr Zwiernik.
“Exponential Varieties.” Proceedings of the London Mathematical Society.
Oxford University Press, 2016. https://doi.org/10.1112/plms/pdv066.
ieee: M. Michałek, B. Sturmfels, C. Uhler, and P. Zwiernik, “Exponential varieties,”
Proceedings of the London Mathematical Society, vol. 112, no. 1. Oxford
University Press, pp. 27–56, 2016.
ista: Michałek M, Sturmfels B, Uhler C, Zwiernik P. 2016. Exponential varieties.
Proceedings of the London Mathematical Society. 112(1), 27–56.
mla: Michałek, Mateusz, et al. “Exponential Varieties.” Proceedings of the London
Mathematical Society, vol. 112, no. 1, Oxford University Press, 2016, pp.
27–56, doi:10.1112/plms/pdv066.
short: M. Michałek, B. Sturmfels, C. Uhler, P. Zwiernik, Proceedings of the London
Mathematical Society 112 (2016) 27–56.
date_created: 2018-12-11T11:52:16Z
date_published: 2016-01-07T00:00:00Z
date_updated: 2021-01-12T06:51:02Z
day: '07'
department:
- _id: CaUh
doi: 10.1112/plms/pdv066
intvolume: ' 112'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1412.6185
month: '01'
oa: 1
oa_version: Preprint
page: 27 - 56
publication: Proceedings of the London Mathematical Society
publication_status: published
publisher: Oxford University Press
publist_id: '5714'
quality_controlled: '1'
scopus_import: 1
status: public
title: Exponential varieties
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 112
year: '2016'
...
---
_id: '1482'
abstract:
- lang: eng
text: Plants have the ability to continously generate new organs by maintaining
populations of stem cells throught their lives. The shoot apical meristem (SAM)
provides a stable environment for the maintenance of stem cells. All cells inside
the SAM divide, yet boundaries and patterns are maintained. Experimental evidence
indicates that patterning is independent of cell lineage, thus a dynamic self-regulatory
mechanism is required. A pivotal role in the organization of the SAM is played
by the WUSCHEL gene (WUS). An important question in this regard is that how WUS
expression is positioned in the SAM via a cell-lineage independent signaling mechanism.
In this study we demonstrate via mathematical modeling that a combination of an
inhibitor of the Cytokinin (CK) receptor, Arabidopsis histidine kinase 4 (AHK4)
and two morphogens originating from the top cell layer, can plausibly account
for the cell lineage-independent centering of WUS expression within SAM. Furthermore,
our laser ablation and microsurgical experiments support the hypothesis that patterning
in SAM occurs at the level of CK reception and signaling. The model suggests that
the interplay between CK signaling, WUS/CLV feedback loop and boundary signals
can account for positioning of the WUS expression, and provides directions for
further experimental investigation.
acknowledgement: We thank J. Traas, B. Müller and V. Reddy for providing seed materials
and Y. Deb for advice regarding the laser ablation experiments. We specially thank
Thomas Laux for stimulating discussions and support in the initial phase of this
project.
article_number: e0147830
author:
- first_name: Milad
full_name: Adibi, Milad
last_name: Adibi
- first_name: Saiko
full_name: Yoshida, Saiko
id: 2E46069C-F248-11E8-B48F-1D18A9856A87
last_name: Yoshida
- first_name: Dolf
full_name: Weijers, Dolf
last_name: Weijers
- first_name: Christian
full_name: Fleck, Christian
last_name: Fleck
citation:
ama: Adibi M, Yoshida S, Weijers D, Fleck C. Centering the organizing center in
the Arabidopsis thaliana shoot apical meristem by a combination of cytokinin signaling
and self-organization. PLoS One. 2016;11(2). doi:10.1371/journal.pone.0147830
apa: Adibi, M., Yoshida, S., Weijers, D., & Fleck, C. (2016). Centering the
organizing center in the Arabidopsis thaliana shoot apical meristem by a combination
of cytokinin signaling and self-organization. PLoS One. Public Library
of Science. https://doi.org/10.1371/journal.pone.0147830
chicago: Adibi, Milad, Saiko Yoshida, Dolf Weijers, and Christian Fleck. “Centering
the Organizing Center in the Arabidopsis Thaliana Shoot Apical Meristem by a Combination
of Cytokinin Signaling and Self-Organization.” PLoS One. Public Library
of Science, 2016. https://doi.org/10.1371/journal.pone.0147830.
ieee: M. Adibi, S. Yoshida, D. Weijers, and C. Fleck, “Centering the organizing
center in the Arabidopsis thaliana shoot apical meristem by a combination of cytokinin
signaling and self-organization,” PLoS One, vol. 11, no. 2. Public Library
of Science, 2016.
ista: Adibi M, Yoshida S, Weijers D, Fleck C. 2016. Centering the organizing center
in the Arabidopsis thaliana shoot apical meristem by a combination of cytokinin
signaling and self-organization. PLoS One. 11(2), e0147830.
mla: Adibi, Milad, et al. “Centering the Organizing Center in the Arabidopsis Thaliana
Shoot Apical Meristem by a Combination of Cytokinin Signaling and Self-Organization.”
PLoS One, vol. 11, no. 2, e0147830, Public Library of Science, 2016, doi:10.1371/journal.pone.0147830.
short: M. Adibi, S. Yoshida, D. Weijers, C. Fleck, PLoS One 11 (2016).
date_created: 2018-12-11T11:52:17Z
date_published: 2016-02-01T00:00:00Z
date_updated: 2021-01-12T06:51:03Z
day: '01'
ddc:
- '570'
department:
- _id: JiFr
doi: 10.1371/journal.pone.0147830
file:
- access_level: open_access
checksum: 6066146e527335030f83aa5924ab72a6
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:14:16Z
date_updated: 2020-07-14T12:44:57Z
file_id: '5066'
file_name: IST-2016-521-v1+1_journal.pone.0147830.PDF
file_size: 4297148
relation: main_file
file_date_updated: 2020-07-14T12:44:57Z
has_accepted_license: '1'
intvolume: ' 11'
issue: '2'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
publication: PLoS One
publication_status: published
publisher: Public Library of Science
publist_id: '5711'
pubrep_id: '521'
quality_controlled: '1'
scopus_import: 1
status: public
title: Centering the organizing center in the Arabidopsis thaliana shoot apical meristem
by a combination of cytokinin signaling and self-organization
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 11
year: '2016'
...
---
_id: '1484'
acknowledgement: We thank Maciek Adamowski for helpful discussions and Qiang Zhu and
Israel Ausin for critical reading of the manuscript. We sincerely apologize to colleagues
whose work we could not include owing to space limitations.
article_type: review
author:
- first_name: Xu
full_name: Chen, Xu
id: 4E5ADCAA-F248-11E8-B48F-1D18A9856A87
last_name: Chen
- first_name: Shuang
full_name: Wu, Shuang
last_name: Wu
- first_name: Zengyu
full_name: Liu, Zengyu
last_name: Liu
- first_name: Jiřĺ
full_name: Friml, Jiřĺ
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Chen X, Wu S, Liu Z, Friml J. Environmental and endogenous control of cortical
microtubule orientation. Trends in Cell Biology. 2016;26(6):409-419. doi:10.1016/j.tcb.2016.02.003
apa: Chen, X., Wu, S., Liu, Z., & Friml, J. (2016). Environmental and endogenous
control of cortical microtubule orientation. Trends in Cell Biology. Cell
Press. https://doi.org/10.1016/j.tcb.2016.02.003
chicago: Chen, Xu, Shuang Wu, Zengyu Liu, and Jiří Friml. “Environmental and Endogenous
Control of Cortical Microtubule Orientation.” Trends in Cell Biology. Cell
Press, 2016. https://doi.org/10.1016/j.tcb.2016.02.003.
ieee: X. Chen, S. Wu, Z. Liu, and J. Friml, “Environmental and endogenous control
of cortical microtubule orientation,” Trends in Cell Biology, vol. 26,
no. 6. Cell Press, pp. 409–419, 2016.
ista: Chen X, Wu S, Liu Z, Friml J. 2016. Environmental and endogenous control of
cortical microtubule orientation. Trends in Cell Biology. 26(6), 409–419.
mla: Chen, Xu, et al. “Environmental and Endogenous Control of Cortical Microtubule
Orientation.” Trends in Cell Biology, vol. 26, no. 6, Cell Press, 2016,
pp. 409–19, doi:10.1016/j.tcb.2016.02.003.
short: X. Chen, S. Wu, Z. Liu, J. Friml, Trends in Cell Biology 26 (2016) 409–419.
date_created: 2018-12-11T11:52:17Z
date_published: 2016-06-01T00:00:00Z
date_updated: 2021-01-12T06:51:04Z
day: '01'
ddc:
- '581'
department:
- _id: JiFr
doi: 10.1016/j.tcb.2016.02.003
file:
- access_level: open_access
checksum: b229e5bb4676ec3e27b7b9ea603b3a63
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:15:34Z
date_updated: 2020-07-14T12:44:57Z
file_id: '5155'
file_name: IST-2018-1002-v1+1_Chen_TICB_2016_proofs.pdf
file_size: 2329117
relation: main_file
file_date_updated: 2020-07-14T12:44:57Z
has_accepted_license: '1'
intvolume: ' 26'
issue: '6'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Submitted Version
page: 409 - 419
publication: Trends in Cell Biology
publication_status: published
publisher: Cell Press
publist_id: '5704'
pubrep_id: '1002'
quality_controlled: '1'
scopus_import: 1
status: public
title: Environmental and endogenous control of cortical microtubule orientation
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 26
year: '2016'
...
---
_id: '1485'
abstract:
- lang: eng
text: In this article the notion of metabolic turnover is revisited in the light
of recent results of out-of-equilibrium thermodynamics. By means of Monte Carlo
methods we perform an exact sampling of the enzymatic fluxes in a genome scale
metabolic network of E. Coli in stationary growth conditions from which we infer
the metabolites turnover times. However the latter are inferred from net fluxes,
and we argue that this approximation is not valid for enzymes working nearby thermodynamic
equilibrium. We recalculate turnover times from total fluxes by performing an
energy balance analysis of the network and recurring to the fluctuation theorem.
We find in many cases values one of order of magnitude lower, implying a faster
picture of intermediate metabolism.
article_number: '016003'
author:
- first_name: Daniele
full_name: De Martino, Daniele
id: 3FF5848A-F248-11E8-B48F-1D18A9856A87
last_name: De Martino
orcid: 0000-0002-5214-4706
citation:
ama: De Martino D. Genome-scale estimate of the metabolic turnover of E. Coli from
the energy balance analysis. Physical Biology. 2016;13(1). doi:10.1088/1478-3975/13/1/016003
apa: De Martino, D. (2016). Genome-scale estimate of the metabolic turnover of E.
Coli from the energy balance analysis. Physical Biology. IOP Publishing
Ltd. https://doi.org/10.1088/1478-3975/13/1/016003
chicago: De Martino, Daniele. “Genome-Scale Estimate of the Metabolic Turnover of
E. Coli from the Energy Balance Analysis.” Physical Biology. IOP Publishing
Ltd., 2016. https://doi.org/10.1088/1478-3975/13/1/016003.
ieee: D. De Martino, “Genome-scale estimate of the metabolic turnover of E. Coli
from the energy balance analysis,” Physical Biology, vol. 13, no. 1. IOP
Publishing Ltd., 2016.
ista: De Martino D. 2016. Genome-scale estimate of the metabolic turnover of E.
Coli from the energy balance analysis. Physical Biology. 13(1), 016003.
mla: De Martino, Daniele. “Genome-Scale Estimate of the Metabolic Turnover of E.
Coli from the Energy Balance Analysis.” Physical Biology, vol. 13, no.
1, 016003, IOP Publishing Ltd., 2016, doi:10.1088/1478-3975/13/1/016003.
short: D. De Martino, Physical Biology 13 (2016).
date_created: 2018-12-11T11:52:18Z
date_published: 2016-01-29T00:00:00Z
date_updated: 2021-01-12T06:51:04Z
day: '29'
department:
- _id: GaTk
doi: 10.1088/1478-3975/13/1/016003
ec_funded: 1
intvolume: ' 13'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1505.04613
month: '01'
oa: 1
oa_version: Preprint
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: Physical Biology
publication_status: published
publisher: IOP Publishing Ltd.
publist_id: '5702'
quality_controlled: '1'
scopus_import: 1
status: public
title: Genome-scale estimate of the metabolic turnover of E. Coli from the energy
balance analysis
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 13
year: '2016'
...
---
_id: '1486'
abstract:
- lang: eng
text: We review recent results concerning the mathematical properties of the Bardeen-Cooper-Schrieffer
(BCS) functional of superconductivity, which were obtained in a series of papers,
partly in collaboration with R. Frank, E. Hamza, S. Naboko, and J. P. Solovej.
Our discussion includes, in particular, an investigation of the critical temperature
for a general class of interaction potentials, as well as a study of its dependence
on external fields. We shall explain how the Ginzburg-Landau model can be derived
from the BCS theory in a suitable parameter regime.
article_number: '021101'
author:
- first_name: Christian
full_name: Hainzl, Christian
last_name: Hainzl
- first_name: Robert
full_name: Seiringer, Robert
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
citation:
ama: Hainzl C, Seiringer R. The Bardeen–Cooper–Schrieffer functional of superconductivity
and its mathematical properties. Journal of Mathematical Physics. 2016;57(2).
doi:10.1063/1.4941723
apa: Hainzl, C., & Seiringer, R. (2016). The Bardeen–Cooper–Schrieffer functional
of superconductivity and its mathematical properties. Journal of Mathematical
Physics. American Institute of Physics. https://doi.org/10.1063/1.4941723
chicago: Hainzl, Christian, and Robert Seiringer. “The Bardeen–Cooper–Schrieffer
Functional of Superconductivity and Its Mathematical Properties.” Journal of
Mathematical Physics. American Institute of Physics, 2016. https://doi.org/10.1063/1.4941723.
ieee: C. Hainzl and R. Seiringer, “The Bardeen–Cooper–Schrieffer functional of superconductivity
and its mathematical properties,” Journal of Mathematical Physics, vol.
57, no. 2. American Institute of Physics, 2016.
ista: Hainzl C, Seiringer R. 2016. The Bardeen–Cooper–Schrieffer functional of superconductivity
and its mathematical properties. Journal of Mathematical Physics. 57(2), 021101.
mla: Hainzl, Christian, and Robert Seiringer. “The Bardeen–Cooper–Schrieffer Functional
of Superconductivity and Its Mathematical Properties.” Journal of Mathematical
Physics, vol. 57, no. 2, 021101, American Institute of Physics, 2016, doi:10.1063/1.4941723.
short: C. Hainzl, R. Seiringer, Journal of Mathematical Physics 57 (2016).
date_created: 2018-12-11T11:52:18Z
date_published: 2016-02-24T00:00:00Z
date_updated: 2021-01-12T06:51:04Z
day: '24'
department:
- _id: RoSe
doi: 10.1063/1.4941723
intvolume: ' 57'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1511.01995
month: '02'
oa: 1
oa_version: Preprint
publication: Journal of Mathematical Physics
publication_status: published
publisher: American Institute of Physics
publist_id: '5701'
quality_controlled: '1'
scopus_import: 1
status: public
title: The Bardeen–Cooper–Schrieffer functional of superconductivity and its mathematical
properties
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 57
year: '2016'
...