---
_id: '9138'
abstract:
- lang: eng
text: Convective self-aggregation, the spontaneous organization of initially scattered
convection into isolated convective clusters despite spatially homogeneous boundary
conditions and forcing, was first recognized and studied in idealized numerical
simulations. While there is a rich history of observational work on convective
clustering and organization, there have been only a few studies that have analyzed
observations to look specifically for processes related to self-aggregation in
models. Here we review observational work in both of these categories and motivate
the need for more of this work. We acknowledge that self-aggregation may appear
to be far-removed from observed convective organization in terms of time scales,
initial conditions, initiation processes, and mean state extremes, but we argue
that these differences vary greatly across the diverse range of model simulations
in the literature and that these comparisons are already offering important insights
into real tropical phenomena. Some preliminary new findings are presented, including
results showing that a self-aggregation simulation with square geometry has too
broad distribution of humidity and is too dry in the driest regions when compared
with radiosonde records from Nauru, while an elongated channel simulation has
realistic representations of atmospheric humidity and its variability. We discuss
recent work increasing our understanding of how organized convection and climate
change may interact, and how model discrepancies related to this question are
prompting interest in observational comparisons. We also propose possible future
directions for observational work related to convective aggregation, including
novel satellite approaches and a ground-based observational network.
article_processing_charge: No
article_type: original
author:
- first_name: Christopher E.
full_name: Holloway, Christopher E.
last_name: Holloway
- first_name: Allison A.
full_name: Wing, Allison A.
last_name: Wing
- first_name: Sandrine
full_name: Bony, Sandrine
last_name: Bony
- first_name: Caroline J
full_name: Muller, Caroline J
id: f978ccb0-3f7f-11eb-b193-b0e2bd13182b
last_name: Muller
orcid: 0000-0001-5836-5350
- first_name: Hirohiko
full_name: Masunaga, Hirohiko
last_name: Masunaga
- first_name: Tristan S.
full_name: L’Ecuyer, Tristan S.
last_name: L’Ecuyer
- first_name: David D.
full_name: Turner, David D.
last_name: Turner
- first_name: Paquita
full_name: Zuidema, Paquita
last_name: Zuidema
citation:
ama: Holloway CE, Wing AA, Bony S, et al. Observing convective aggregation. Surveys
in Geophysics. 2017;38(6):1199-1236. doi:10.1007/s10712-017-9419-1
apa: Holloway, C. E., Wing, A. A., Bony, S., Muller, C. J., Masunaga, H., L’Ecuyer,
T. S., … Zuidema, P. (2017). Observing convective aggregation. Surveys in Geophysics.
Springer Nature. https://doi.org/10.1007/s10712-017-9419-1
chicago: Holloway, Christopher E., Allison A. Wing, Sandrine Bony, Caroline J Muller,
Hirohiko Masunaga, Tristan S. L’Ecuyer, David D. Turner, and Paquita Zuidema.
“Observing Convective Aggregation.” Surveys in Geophysics. Springer Nature,
2017. https://doi.org/10.1007/s10712-017-9419-1.
ieee: C. E. Holloway et al., “Observing convective aggregation,” Surveys
in Geophysics, vol. 38, no. 6. Springer Nature, pp. 1199–1236, 2017.
ista: Holloway CE, Wing AA, Bony S, Muller CJ, Masunaga H, L’Ecuyer TS, Turner DD,
Zuidema P. 2017. Observing convective aggregation. Surveys in Geophysics. 38(6),
1199–1236.
mla: Holloway, Christopher E., et al. “Observing Convective Aggregation.” Surveys
in Geophysics, vol. 38, no. 6, Springer Nature, 2017, pp. 1199–236, doi:10.1007/s10712-017-9419-1.
short: C.E. Holloway, A.A. Wing, S. Bony, C.J. Muller, H. Masunaga, T.S. L’Ecuyer,
D.D. Turner, P. Zuidema, Surveys in Geophysics 38 (2017) 1199–1236.
date_created: 2021-02-15T14:20:38Z
date_published: 2017-11-01T00:00:00Z
date_updated: 2022-01-24T12:43:13Z
day: '01'
doi: 10.1007/s10712-017-9419-1
extern: '1'
intvolume: ' 38'
issue: '6'
keyword:
- Geochemistry and Petrology
- Geophysics
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1007/s10712-017-9419-1
month: '11'
oa: 1
oa_version: Published Version
page: 1199-1236
publication: Surveys in Geophysics
publication_identifier:
issn:
- 0169-3298
- 1573-0956
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Observing convective aggregation
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 38
year: '2017'
...
---
_id: '9139'
abstract:
- lang: eng
text: Organized convection in the tropics occurs across a range of spatial and temporal
scales and strongly influences cloud cover and humidity. One mode of organization
found is “self-aggregation,” in which moist convection spontaneously organizes
into one or several isolated clusters despite spatially homogeneous boundary conditions
and forcing. Self-aggregation is driven by interactions between clouds, moisture,
radiation, surface fluxes, and circulation, and occurs in a wide variety of idealized
simulations of radiative–convective equilibrium. Here we provide a review of convective
self-aggregation in numerical simulations, including its character, causes, and
effects. We describe the evolution of self-aggregation including its time and
length scales and the physical mechanisms leading to its triggering and maintenance,
and we also discuss possible links to climate and climate change.
article_processing_charge: No
article_type: original
author:
- first_name: Allison A.
full_name: Wing, Allison A.
last_name: Wing
- first_name: Kerry
full_name: Emanuel, Kerry
last_name: Emanuel
- first_name: Christopher E.
full_name: Holloway, Christopher E.
last_name: Holloway
- first_name: Caroline J
full_name: Muller, Caroline J
id: f978ccb0-3f7f-11eb-b193-b0e2bd13182b
last_name: Muller
orcid: 0000-0001-5836-5350
citation:
ama: 'Wing AA, Emanuel K, Holloway CE, Muller CJ. Convective self-aggregation in
numerical simulations: A review. Surveys in Geophysics. 2017;38(6):1173-1197.
doi:10.1007/s10712-017-9408-4'
apa: 'Wing, A. A., Emanuel, K., Holloway, C. E., & Muller, C. J. (2017). Convective
self-aggregation in numerical simulations: A review. Surveys in Geophysics.
Springer Nature. https://doi.org/10.1007/s10712-017-9408-4'
chicago: 'Wing, Allison A., Kerry Emanuel, Christopher E. Holloway, and Caroline
J Muller. “Convective Self-Aggregation in Numerical Simulations: A Review.” Surveys
in Geophysics. Springer Nature, 2017. https://doi.org/10.1007/s10712-017-9408-4.'
ieee: 'A. A. Wing, K. Emanuel, C. E. Holloway, and C. J. Muller, “Convective self-aggregation
in numerical simulations: A review,” Surveys in Geophysics, vol. 38, no.
6. Springer Nature, pp. 1173–1197, 2017.'
ista: 'Wing AA, Emanuel K, Holloway CE, Muller CJ. 2017. Convective self-aggregation
in numerical simulations: A review. Surveys in Geophysics. 38(6), 1173–1197.'
mla: 'Wing, Allison A., et al. “Convective Self-Aggregation in Numerical Simulations:
A Review.” Surveys in Geophysics, vol. 38, no. 6, Springer Nature, 2017,
pp. 1173–97, doi:10.1007/s10712-017-9408-4.'
short: A.A. Wing, K. Emanuel, C.E. Holloway, C.J. Muller, Surveys in Geophysics
38 (2017) 1173–1197.
date_created: 2021-02-15T14:20:56Z
date_published: 2017-11-01T00:00:00Z
date_updated: 2022-01-24T12:42:36Z
day: '01'
doi: 10.1007/s10712-017-9408-4
extern: '1'
intvolume: ' 38'
issue: '6'
keyword:
- Geochemistry and Petrology
- Geophysics
language:
- iso: eng
month: '11'
oa_version: None
page: 1173-1197
publication: Surveys in Geophysics
publication_identifier:
issn:
- 0169-3298
- 1573-0956
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: 'Convective self-aggregation in numerical simulations: A review'
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 38
year: '2017'
...
---
_id: '914'
abstract:
- lang: eng
text: Infections with potentially lethal pathogens may negatively affect an individual’s
lifespan and decrease its reproductive value. The terminal investment hypothesis
predicts that individuals faced with a reduced survival should invest more into
reproduction instead of maintenance and growth. Several studies suggest that individuals
are indeed able to estimate their body condition and to increase their reproductive
effort with approaching death, while other studies gave ambiguous results. We
investigate whether queens of a perennial social insect (ant) are able to boost
their reproduction following infection with an obligate killing pathogen. Social
insect queens are special with regard to reproduction and aging, as they outlive
conspecific non-reproductive workers. Moreover, in the ant Cardiocondyla obscurior,
fecundity increases with queen age. However, it remained unclear whether this
reflects negative reproductive senescence or terminal investment in response to
approaching death. Here, we test whether queens of C. obscurior react to infection
with the entomopathogenic fungus Metarhizium brunneum by an increased egg-laying
rate. We show that a fungal infection triggers a reinforced investment in reproduction
in queens. This adjustment of the reproductive rate by ant queens is consistent
with predictions of the terminal investment hypothesis and is reported for the
first time in a social insect.
acknowledgement: We thank two anonymous reviewers for helpful suggestions on the manuscript.
article_number: '170547'
article_processing_charge: No
author:
- first_name: Julia
full_name: Giehr, Julia
last_name: Giehr
- first_name: Anna V
full_name: Grasse, Anna V
id: 406F989C-F248-11E8-B48F-1D18A9856A87
last_name: Grasse
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
- first_name: Jürgen
full_name: Heinze, Jürgen
last_name: Heinze
- first_name: Alexandra
full_name: Schrempf, Alexandra
last_name: Schrempf
citation:
ama: Giehr J, Grasse AV, Cremer S, Heinze J, Schrempf A. Ant queens increase their
reproductive efforts after pathogen infection. Royal Society Open Science.
2017;4(7). doi:10.1098/rsos.170547
apa: Giehr, J., Grasse, A. V., Cremer, S., Heinze, J., & Schrempf, A. (2017).
Ant queens increase their reproductive efforts after pathogen infection. Royal
Society Open Science. Royal Society, The. https://doi.org/10.1098/rsos.170547
chicago: Giehr, Julia, Anna V Grasse, Sylvia Cremer, Jürgen Heinze, and Alexandra
Schrempf. “Ant Queens Increase Their Reproductive Efforts after Pathogen Infection.”
Royal Society Open Science. Royal Society, The, 2017. https://doi.org/10.1098/rsos.170547.
ieee: J. Giehr, A. V. Grasse, S. Cremer, J. Heinze, and A. Schrempf, “Ant queens
increase their reproductive efforts after pathogen infection,” Royal Society
Open Science, vol. 4, no. 7. Royal Society, The, 2017.
ista: Giehr J, Grasse AV, Cremer S, Heinze J, Schrempf A. 2017. Ant queens increase
their reproductive efforts after pathogen infection. Royal Society Open Science.
4(7), 170547.
mla: Giehr, Julia, et al. “Ant Queens Increase Their Reproductive Efforts after
Pathogen Infection.” Royal Society Open Science, vol. 4, no. 7, 170547,
Royal Society, The, 2017, doi:10.1098/rsos.170547.
short: J. Giehr, A.V. Grasse, S. Cremer, J. Heinze, A. Schrempf, Royal Society Open
Science 4 (2017).
date_created: 2018-12-11T11:49:10Z
date_published: 2017-07-05T00:00:00Z
date_updated: 2023-09-26T15:45:47Z
day: '05'
ddc:
- '576'
- '592'
department:
- _id: SyCr
doi: 10.1098/rsos.170547
external_id:
isi:
- '000406670000025'
file:
- access_level: open_access
checksum: 351ae5e7a37e6e7d9295cd41146c4190
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:08:24Z
date_updated: 2020-07-14T12:48:15Z
file_id: '4684'
file_name: IST-2017-849-v1+1_2017_Grasse_Cremer_AntQueens.pdf
file_size: 530412
relation: main_file
file_date_updated: 2020-07-14T12:48:15Z
has_accepted_license: '1'
intvolume: ' 4'
isi: 1
issue: '7'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
publication: Royal Society Open Science
publication_identifier:
issn:
- '20545703'
publication_status: published
publisher: Royal Society, The
publist_id: '6527'
pubrep_id: '849'
quality_controlled: '1'
related_material:
record:
- id: '9853'
relation: research_data
status: public
scopus_import: '1'
status: public
title: Ant queens increase their reproductive efforts after pathogen infection
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 4
year: '2017'
...
---
_id: '915'
abstract:
- lang: eng
text: We propose a dual decomposition and linear program relaxation of the NP-hard
minimum cost multicut problem. Unlike other polyhedral relaxations of the multicut
polytope, it is amenable to efficient optimization by message passing. Like other
polyhedral relaxations, it can be tightened efficiently by cutting planes. We
define an algorithm that alternates between message passing and efficient separation
of cycle- and odd-wheel inequalities. This algorithm is more efficient than state-of-the-art
algorithms based on linear programming, including algorithms written in the framework
of leading commercial software, as we show in experiments with large instances
of the problem from applications in computer vision, biomedical image analysis
and data mining.
article_processing_charge: No
author:
- first_name: Paul
full_name: Swoboda, Paul
id: 446560C6-F248-11E8-B48F-1D18A9856A87
last_name: Swoboda
- first_name: Bjoern
full_name: Andres, Bjoern
last_name: Andres
citation:
ama: 'Swoboda P, Andres B. A message passing algorithm for the minimum cost multicut
problem. In: Vol 2017. IEEE; 2017:4990-4999. doi:10.1109/CVPR.2017.530'
apa: 'Swoboda, P., & Andres, B. (2017). A message passing algorithm for the
minimum cost multicut problem (Vol. 2017, pp. 4990–4999). Presented at the CVPR:
Computer Vision and Pattern Recognition, Honolulu, HA, United States: IEEE. https://doi.org/10.1109/CVPR.2017.530'
chicago: Swoboda, Paul, and Bjoern Andres. “A Message Passing Algorithm for the
Minimum Cost Multicut Problem,” 2017:4990–99. IEEE, 2017. https://doi.org/10.1109/CVPR.2017.530.
ieee: 'P. Swoboda and B. Andres, “A message passing algorithm for the minimum cost
multicut problem,” presented at the CVPR: Computer Vision and Pattern Recognition,
Honolulu, HA, United States, 2017, vol. 2017, pp. 4990–4999.'
ista: 'Swoboda P, Andres B. 2017. A message passing algorithm for the minimum cost
multicut problem. CVPR: Computer Vision and Pattern Recognition vol. 2017, 4990–4999.'
mla: Swoboda, Paul, and Bjoern Andres. A Message Passing Algorithm for the Minimum
Cost Multicut Problem. Vol. 2017, IEEE, 2017, pp. 4990–99, doi:10.1109/CVPR.2017.530.
short: P. Swoboda, B. Andres, in:, IEEE, 2017, pp. 4990–4999.
conference:
end_date: 2017-07-26
location: Honolulu, HA, United States
name: 'CVPR: Computer Vision and Pattern Recognition'
start_date: 2017-07-21
date_created: 2018-12-11T11:49:11Z
date_published: 2017-07-01T00:00:00Z
date_updated: 2023-09-26T15:43:27Z
day: '01'
ddc:
- '000'
department:
- _id: VlKo
doi: 10.1109/CVPR.2017.530
ec_funded: 1
external_id:
isi:
- '000418371405009'
file:
- access_level: open_access
checksum: 7e51dacefa693574581a32da3eff63dc
content_type: application/pdf
creator: dernst
date_created: 2019-01-18T12:52:46Z
date_updated: 2020-07-14T12:48:15Z
file_id: '5849'
file_name: Swoboda_A_Message_Passing_CVPR_2017_paper.pdf
file_size: 883264
relation: main_file
file_date_updated: 2020-07-14T12:48:15Z
has_accepted_license: '1'
intvolume: ' 2017'
isi: 1
language:
- iso: eng
month: '07'
oa: 1
oa_version: Submitted Version
page: 4990-4999
project:
- _id: 25FBA906-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '616160'
name: 'Discrete Optimization in Computer Vision: Theory and Practice'
publication_identifier:
isbn:
- 978-153860457-1
publication_status: published
publisher: IEEE
publist_id: '6526'
quality_controlled: '1'
scopus_import: '1'
status: public
title: A message passing algorithm for the minimum cost multicut problem
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 2017
year: '2017'
...
---
_id: '9152'
abstract:
- lang: eng
text: Previous numerical studies of the dissipation of internal tides in idealized
settings suggest the existence of a critical latitude (~29°) where dissipation
is enhanced. But observations only indicate a modest enhancement at this latitude.
To resolve this difference between observational and numerical results, the authors
study the latitudinal dependence of internal tides’ dissipation in more realistic
conditions. In particular, the ocean is not a quiescent medium; the presence of
large-scale currents or mesoscale eddies can impact the propagation and dissipation
of internal tides. This paper investigates the impact of a weak background mean
current in numerical simulations. The authors focus on the local dissipation of
high spatial mode internal waves near their generation site. The vertical profile
of dissipation and its variation with latitude without the mean current are consistent
with earlier studies. But adding a weak mean current has a major impact on the
latitudinal distribution of dissipation. The peak at the critical latitude disappears,
and the dissipation is closer to a constant, albeit with two weak peaks at ~25°
and ~35° latitude. This disappearance results from the Doppler shift of the internal
tides’ frequency, which hinders the nonlinear transfer of energy to small-scale
secondary waves via the parametric subharmonic instability (PSI). The new two
weak peaks correspond to the Doppler-shifted critical latitudes of the left- and
right-propagating waves. The results are confirmed in simulations with simple
sinusoidal topography. Thus, although nonlinear transfers via PSI are efficient
at dissipating internal tides, the exact location of the dissipation is sensitive
to large-scale oceanic conditions.
article_processing_charge: No
article_type: original
author:
- first_name: O.
full_name: Richet, O.
last_name: Richet
- first_name: Caroline J
full_name: Muller, Caroline J
id: f978ccb0-3f7f-11eb-b193-b0e2bd13182b
last_name: Muller
orcid: 0000-0001-5836-5350
- first_name: J.-M.
full_name: Chomaz, J.-M.
last_name: Chomaz
citation:
ama: Richet O, Muller CJ, Chomaz J-M. Impact of a mean current on the internal tide
energy dissipation at the critical latitude. Journal of Physical Oceanography.
2017;47(6):1457-1472. doi:10.1175/jpo-d-16-0197.1
apa: Richet, O., Muller, C. J., & Chomaz, J.-M. (2017). Impact of a mean current
on the internal tide energy dissipation at the critical latitude. Journal of
Physical Oceanography. American Meteorological Society. https://doi.org/10.1175/jpo-d-16-0197.1
chicago: Richet, O., Caroline J Muller, and J.-M. Chomaz. “Impact of a Mean Current
on the Internal Tide Energy Dissipation at the Critical Latitude.” Journal
of Physical Oceanography. American Meteorological Society, 2017. https://doi.org/10.1175/jpo-d-16-0197.1.
ieee: O. Richet, C. J. Muller, and J.-M. Chomaz, “Impact of a mean current on the
internal tide energy dissipation at the critical latitude,” Journal of Physical
Oceanography, vol. 47, no. 6. American Meteorological Society, pp. 1457–1472,
2017.
ista: Richet O, Muller CJ, Chomaz J-M. 2017. Impact of a mean current on the internal
tide energy dissipation at the critical latitude. Journal of Physical Oceanography.
47(6), 1457–1472.
mla: Richet, O., et al. “Impact of a Mean Current on the Internal Tide Energy Dissipation
at the Critical Latitude.” Journal of Physical Oceanography, vol. 47, no.
6, American Meteorological Society, 2017, pp. 1457–72, doi:10.1175/jpo-d-16-0197.1.
short: O. Richet, C.J. Muller, J.-M. Chomaz, Journal of Physical Oceanography 47
(2017) 1457–1472.
date_created: 2021-02-15T15:11:04Z
date_published: 2017-06-01T00:00:00Z
date_updated: 2022-01-24T13:36:31Z
day: '01'
doi: 10.1175/jpo-d-16-0197.1
extern: '1'
intvolume: ' 47'
issue: '6'
keyword:
- Oceanography
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1175/JPO-D-16-0197.1
month: '06'
oa: 1
oa_version: Published Version
page: 1457-1472
publication: Journal of Physical Oceanography
publication_identifier:
issn:
- 0022-3670
- 1520-0485
publication_status: published
publisher: American Meteorological Society
quality_controlled: '1'
status: public
title: Impact of a mean current on the internal tide energy dissipation at the critical
latitude
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 47
year: '2017'
...
---
_id: '916'
abstract:
- lang: eng
text: We study the quadratic assignment problem, in computer vision also known as
graph matching. Two leading solvers for this problem optimize the Lagrange decomposition
duals with sub-gradient and dual ascent (also known as message passing) updates.
We explore this direction further and propose several additional Lagrangean relaxations
of the graph matching problem along with corresponding algorithms, which are all
based on a common dual ascent framework. Our extensive empirical evaluation gives
several theoretical insights and suggests a new state-of-the-art anytime solver
for the considered problem. Our improvement over state-of-the-art is particularly
visible on a new dataset with large-scale sparse problem instances containing
more than 500 graph nodes each.
article_processing_charge: No
author:
- first_name: Paul
full_name: Swoboda, Paul
id: 446560C6-F248-11E8-B48F-1D18A9856A87
last_name: Swoboda
- first_name: Carsten
full_name: Rother, Carsten
last_name: Rother
- first_name: Carsten
full_name: Abu Alhaija, Carsten
last_name: Abu Alhaija
- first_name: Dagmar
full_name: Kainmueller, Dagmar
last_name: Kainmueller
- first_name: Bogdan
full_name: Savchynskyy, Bogdan
last_name: Savchynskyy
citation:
ama: 'Swoboda P, Rother C, Abu Alhaija C, Kainmueller D, Savchynskyy B. A study
of lagrangean decompositions and dual ascent solvers for graph matching. In: Vol
2017. IEEE; 2017:7062-7071. doi:10.1109/CVPR.2017.747'
apa: 'Swoboda, P., Rother, C., Abu Alhaija, C., Kainmueller, D., & Savchynskyy,
B. (2017). A study of lagrangean decompositions and dual ascent solvers for graph
matching (Vol. 2017, pp. 7062–7071). Presented at the CVPR: Computer Vision and
Pattern Recognition, Honolulu, HA, United States: IEEE. https://doi.org/10.1109/CVPR.2017.747'
chicago: Swoboda, Paul, Carsten Rother, Carsten Abu Alhaija, Dagmar Kainmueller,
and Bogdan Savchynskyy. “A Study of Lagrangean Decompositions and Dual Ascent
Solvers for Graph Matching,” 2017:7062–71. IEEE, 2017. https://doi.org/10.1109/CVPR.2017.747.
ieee: 'P. Swoboda, C. Rother, C. Abu Alhaija, D. Kainmueller, and B. Savchynskyy,
“A study of lagrangean decompositions and dual ascent solvers for graph matching,”
presented at the CVPR: Computer Vision and Pattern Recognition, Honolulu, HA,
United States, 2017, vol. 2017, pp. 7062–7071.'
ista: 'Swoboda P, Rother C, Abu Alhaija C, Kainmueller D, Savchynskyy B. 2017. A
study of lagrangean decompositions and dual ascent solvers for graph matching.
CVPR: Computer Vision and Pattern Recognition vol. 2017, 7062–7071.'
mla: Swoboda, Paul, et al. A Study of Lagrangean Decompositions and Dual Ascent
Solvers for Graph Matching. Vol. 2017, IEEE, 2017, pp. 7062–71, doi:10.1109/CVPR.2017.747.
short: P. Swoboda, C. Rother, C. Abu Alhaija, D. Kainmueller, B. Savchynskyy, in:,
IEEE, 2017, pp. 7062–7071.
conference:
end_date: 2017-07-26
location: Honolulu, HA, United States
name: 'CVPR: Computer Vision and Pattern Recognition'
start_date: 2017-07-21
date_created: 2018-12-11T11:49:11Z
date_published: 2017-01-01T00:00:00Z
date_updated: 2023-09-26T15:41:40Z
day: '01'
ddc:
- '000'
department:
- _id: VlKo
doi: 10.1109/CVPR.2017.747
ec_funded: 1
external_id:
isi:
- '000418371407018'
file:
- access_level: open_access
checksum: e38a2740daad1ea178465843b5072906
content_type: application/pdf
creator: dernst
date_created: 2019-01-18T12:49:38Z
date_updated: 2020-07-14T12:48:15Z
file_id: '5848'
file_name: 2017_CVPR_Swoboda2.pdf
file_size: 944332
relation: main_file
file_date_updated: 2020-07-14T12:48:15Z
has_accepted_license: '1'
intvolume: ' 2017'
isi: 1
language:
- iso: eng
month: '01'
oa: 1
oa_version: Submitted Version
page: 7062-7071
project:
- _id: 25FBA906-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '616160'
name: 'Discrete Optimization in Computer Vision: Theory and Practice'
publication_identifier:
isbn:
- 978-153860457-1
publication_status: published
publisher: IEEE
publist_id: '6525'
quality_controlled: '1'
scopus_import: '1'
status: public
title: A study of lagrangean decompositions and dual ascent solvers for graph matching
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 2017
year: '2017'
...
---
_id: '9165'
abstract:
- lang: eng
text: Advances in colloidal synthesis allow for the design of particles with controlled
patches. This article reviews routes towards colloidal locomotion, where energy
is consumed and converted into motion, and its implementation with active patchy
particles. A special emphasis is given to phoretic swimmers, where the self-propulsion
originates from an interfacial phenomenon, raising experimental challenges and
opening up opportunities for particles with controlled anisotropic surface chemistry
and novel behaviors.
article_processing_charge: No
article_type: original
author:
- first_name: A.
full_name: Aubret, A.
last_name: Aubret
- first_name: S.
full_name: Ramananarivo, S.
last_name: Ramananarivo
- first_name: Jérémie A
full_name: Palacci, Jérémie A
id: 8fb92548-2b22-11eb-b7c1-a3f0d08d7c7d
last_name: Palacci
orcid: 0000-0002-7253-9465
citation:
ama: 'Aubret A, Ramananarivo S, Palacci JA. Eppur si muove, and yet it moves: Patchy
(phoretic) swimmers. Current Opinion in Colloid & Interface Science.
2017;30:81-89. doi:10.1016/j.cocis.2017.05.007'
apa: 'Aubret, A., Ramananarivo, S., & Palacci, J. A. (2017). Eppur si muove,
and yet it moves: Patchy (phoretic) swimmers. Current Opinion in Colloid &
Interface Science. Elsevier. https://doi.org/10.1016/j.cocis.2017.05.007'
chicago: 'Aubret, A., S. Ramananarivo, and Jérémie A Palacci. “Eppur Si Muove, and
yet It Moves: Patchy (Phoretic) Swimmers.” Current Opinion in Colloid &
Interface Science. Elsevier, 2017. https://doi.org/10.1016/j.cocis.2017.05.007.'
ieee: 'A. Aubret, S. Ramananarivo, and J. A. Palacci, “Eppur si muove, and yet it
moves: Patchy (phoretic) swimmers,” Current Opinion in Colloid & Interface
Science, vol. 30. Elsevier, pp. 81–89, 2017.'
ista: 'Aubret A, Ramananarivo S, Palacci JA. 2017. Eppur si muove, and yet it moves:
Patchy (phoretic) swimmers. Current Opinion in Colloid & Interface Science.
30, 81–89.'
mla: 'Aubret, A., et al. “Eppur Si Muove, and yet It Moves: Patchy (Phoretic) Swimmers.”
Current Opinion in Colloid & Interface Science, vol. 30, Elsevier,
2017, pp. 81–89, doi:10.1016/j.cocis.2017.05.007.'
short: A. Aubret, S. Ramananarivo, J.A. Palacci, Current Opinion in Colloid &
Interface Science 30 (2017) 81–89.
date_created: 2021-02-18T14:29:42Z
date_published: 2017-07-01T00:00:00Z
date_updated: 2021-02-22T09:32:11Z
day: '01'
doi: 10.1016/j.cocis.2017.05.007
extern: '1'
intvolume: ' 30'
language:
- iso: eng
month: '07'
oa_version: None
page: 81-89
publication: Current Opinion in Colloid & Interface Science
publication_identifier:
issn:
- 1359-0294
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Eppur si muove, and yet it moves: Patchy (phoretic) swimmers'
type: journal_article
user_id: D865714E-FA4E-11E9-B85B-F5C5E5697425
volume: 30
year: '2017'
...
---
_id: '917'
abstract:
- lang: eng
text: We propose a general dual ascent framework for Lagrangean decomposition
of combinatorial problems. Although methods of this type have shown their efficiency
for a number of problems, so far there was no general algorithm applicable to
multiple problem types. In this work, we propose such a general algorithm. It
depends on several parameters, which can be used to optimize its performance in
each particular setting. We demonstrate efficacy of our method on graph matching
and multicut problems, where it outperforms state-of-the-art solvers including
those based on subgradient optimization and off-the-shelf linear programming solvers.
article_processing_charge: No
author:
- first_name: Paul
full_name: Swoboda, Paul
id: 446560C6-F248-11E8-B48F-1D18A9856A87
last_name: Swoboda
- first_name: Jan
full_name: Kuske, Jan
last_name: Kuske
- first_name: Bogdan
full_name: Savchynskyy, Bogdan
last_name: Savchynskyy
citation:
ama: 'Swoboda P, Kuske J, Savchynskyy B. A dual ascent framework for Lagrangean
decomposition of combinatorial problems. In: Vol 2017. IEEE; 2017:4950-4960. doi:10.1109/CVPR.2017.526'
apa: 'Swoboda, P., Kuske, J., & Savchynskyy, B. (2017). A dual ascent framework
for Lagrangean decomposition of combinatorial problems (Vol. 2017, pp. 4950–4960).
Presented at the CVPR: Computer Vision and Pattern Recognition, Honolulu, HA,
United States: IEEE. https://doi.org/10.1109/CVPR.2017.526'
chicago: Swoboda, Paul, Jan Kuske, and Bogdan Savchynskyy. “A Dual Ascent Framework
for Lagrangean Decomposition of Combinatorial Problems,” 2017:4950–60. IEEE, 2017.
https://doi.org/10.1109/CVPR.2017.526.
ieee: 'P. Swoboda, J. Kuske, and B. Savchynskyy, “A dual ascent framework for Lagrangean
decomposition of combinatorial problems,” presented at the CVPR: Computer Vision
and Pattern Recognition, Honolulu, HA, United States, 2017, vol. 2017, pp. 4950–4960.'
ista: 'Swoboda P, Kuske J, Savchynskyy B. 2017. A dual ascent framework for Lagrangean
decomposition of combinatorial problems. CVPR: Computer Vision and Pattern Recognition
vol. 2017, 4950–4960.'
mla: Swoboda, Paul, et al. A Dual Ascent Framework for Lagrangean Decomposition
of Combinatorial Problems. Vol. 2017, IEEE, 2017, pp. 4950–60, doi:10.1109/CVPR.2017.526.
short: P. Swoboda, J. Kuske, B. Savchynskyy, in:, IEEE, 2017, pp. 4950–4960.
conference:
end_date: 2017-07-26
location: Honolulu, HA, United States
name: 'CVPR: Computer Vision and Pattern Recognition'
start_date: 2017-07-21
date_created: 2018-12-11T11:49:11Z
date_published: 2017-07-01T00:00:00Z
date_updated: 2023-09-26T15:41:11Z
day: '01'
ddc:
- '000'
department:
- _id: VlKo
doi: 10.1109/CVPR.2017.526
ec_funded: 1
external_id:
isi:
- '000418371405005'
file:
- access_level: open_access
checksum: 72fd291046bd8e5717961bd68f6b6f03
content_type: application/pdf
creator: dernst
date_created: 2019-01-18T12:45:55Z
date_updated: 2020-07-14T12:48:15Z
file_id: '5847'
file_name: 2017_CVPR_Swoboda.pdf
file_size: 898652
relation: main_file
file_date_updated: 2020-07-14T12:48:15Z
has_accepted_license: '1'
intvolume: ' 2017'
isi: 1
language:
- iso: eng
month: '07'
oa: 1
oa_version: Submitted Version
page: 4950-4960
project:
- _id: 25FBA906-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '616160'
name: 'Discrete Optimization in Computer Vision: Theory and Practice'
publication_identifier:
isbn:
- 978-153860457-1
publication_status: published
publisher: IEEE
publist_id: '6524'
quality_controlled: '1'
scopus_import: '1'
status: public
title: A dual ascent framework for Lagrangean decomposition of combinatorial problems
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 2017
year: '2017'
...
---
_id: '9190'
abstract:
- lang: eng
text: Plant meristems carry pools of continuously active stem cells, whose
activity is controlled by developmental and environmental signals. After stem
cell division, daughter cells that exit the stem cell domain acquire transit amplifying
cell identity before they are incorporated into organs and differentiate. In this
study, we used an integrated approach to elucidate the role of HECATE (HEC) genes
in regulating developmental trajectories of shoot stem cells in Arabidopsis thaliana.
Our work reveals that HEC function stabilizes cell fate in distinct zones of the
shoot meristem thereby controlling the spatio-temporal dynamics of stem cell differentiation.
Importantly, this activity is concomitant with the local modulation of cellular
responses to cytokinin and auxin, two key phytohormones regulating cell behaviour.
Mechanistically, we show that HEC factors transcriptionally control and physically
interact with MONOPTEROS (MP), a key regulator of auxin signalling, and modulate
the autocatalytic stabilization of auxin signalling output.
article_number: e30135
article_processing_charge: No
article_type: original
author:
- first_name: Christophe
full_name: Gaillochet, Christophe
last_name: Gaillochet
- first_name: Thomas
full_name: Stiehl, Thomas
last_name: Stiehl
- first_name: Christian
full_name: Wenzl, Christian
last_name: Wenzl
- first_name: Juan-José
full_name: Ripoll, Juan-José
last_name: Ripoll
- first_name: Lindsay J
full_name: Bailey-Steinitz, Lindsay J
last_name: Bailey-Steinitz
- first_name: Lanxin
full_name: Li, Lanxin
id: 367EF8FA-F248-11E8-B48F-1D18A9856A87
last_name: Li
orcid: 0000-0002-5607-272X
- first_name: Anne
full_name: Pfeiffer, Anne
last_name: Pfeiffer
- first_name: Andrej
full_name: Miotk, Andrej
last_name: Miotk
- first_name: Jana P
full_name: Hakenjos, Jana P
last_name: Hakenjos
- first_name: Joachim
full_name: Forner, Joachim
last_name: Forner
- first_name: Martin F
full_name: Yanofsky, Martin F
last_name: Yanofsky
- first_name: Anna
full_name: Marciniak-Czochra, Anna
last_name: Marciniak-Czochra
- first_name: Jan U
full_name: Lohmann, Jan U
last_name: Lohmann
citation:
ama: Gaillochet C, Stiehl T, Wenzl C, et al. Control of plant cell fate transitions
by transcriptional and hormonal signals. eLife. 2017;6. doi:10.7554/elife.30135
apa: Gaillochet, C., Stiehl, T., Wenzl, C., Ripoll, J.-J., Bailey-Steinitz, L. J.,
Li, L., … Lohmann, J. U. (2017). Control of plant cell fate transitions by transcriptional
and hormonal signals. ELife. eLife Sciences Publications. https://doi.org/10.7554/elife.30135
chicago: Gaillochet, Christophe, Thomas Stiehl, Christian Wenzl, Juan-José Ripoll,
Lindsay J Bailey-Steinitz, Lanxin Li, Anne Pfeiffer, et al. “Control of Plant
Cell Fate Transitions by Transcriptional and Hormonal Signals.” ELife.
eLife Sciences Publications, 2017. https://doi.org/10.7554/elife.30135.
ieee: C. Gaillochet et al., “Control of plant cell fate transitions by transcriptional
and hormonal signals,” eLife, vol. 6. eLife Sciences Publications, 2017.
ista: Gaillochet C, Stiehl T, Wenzl C, Ripoll J-J, Bailey-Steinitz LJ, Li L, Pfeiffer
A, Miotk A, Hakenjos JP, Forner J, Yanofsky MF, Marciniak-Czochra A, Lohmann JU.
2017. Control of plant cell fate transitions by transcriptional and hormonal signals.
eLife. 6, e30135.
mla: Gaillochet, Christophe, et al. “Control of Plant Cell Fate Transitions by Transcriptional
and Hormonal Signals.” ELife, vol. 6, e30135, eLife Sciences Publications,
2017, doi:10.7554/elife.30135.
short: C. Gaillochet, T. Stiehl, C. Wenzl, J.-J. Ripoll, L.J. Bailey-Steinitz, L.
Li, A. Pfeiffer, A. Miotk, J.P. Hakenjos, J. Forner, M.F. Yanofsky, A. Marciniak-Czochra,
J.U. Lohmann, ELife 6 (2017).
date_created: 2021-02-24T17:06:13Z
date_published: 2017-10-23T00:00:00Z
date_updated: 2021-03-02T09:33:54Z
day: '23'
ddc:
- '580'
doi: 10.7554/elife.30135
extern: '1'
external_id:
pmid:
- '29058667'
file:
- access_level: open_access
checksum: 51c8968a845df5077643c3e3e139d34f
content_type: application/pdf
creator: dernst
date_created: 2021-03-02T09:29:56Z
date_updated: 2021-03-02T09:29:56Z
file_id: '9214'
file_name: 2017_eLife_Gaillochet.pdf
file_size: 11669407
relation: main_file
success: 1
file_date_updated: 2021-03-02T09:29:56Z
has_accepted_license: '1'
intvolume: ' 6'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
pmid: 1
publication: eLife
publication_identifier:
issn:
- 2050-084X
publication_status: published
publisher: eLife Sciences Publications
quality_controlled: '1'
status: public
title: Control of plant cell fate transitions by transcriptional and hormonal signals
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2017'
...
---
_id: '93'
abstract:
- lang: eng
text: An electro-optomechanical device capable of microwave-to-optics conversion
has recently been demonstrated, with the vision of enabling optical networks of
superconducting qubits. Here we present an improved converter design that uses
a three-dimensional microwave cavity for coupling between the microwave transmission
line and an integrated LC resonator on the converter chip. The new design simplifies
the optical assembly and decouples it from the microwave part of the setup. Experimental
demonstrations show that the modular device assembly allows us to flexibly tune
the microwave coupling to the converter chip while maintaining small loss. We
also find that electromechanical experiments are not impacted by the additional
microwave cavity. Our design is compatible with a high-finesse optical cavity
and will improve optical performance.
article_number: '094701'
arxiv: 1
author:
- first_name: Tim
full_name: Menke, Tim
last_name: Menke
- first_name: Peter
full_name: Burns, Peter
last_name: Burns
- first_name: Andrew P
full_name: Higginbotham, Andrew P
id: 4AD6785A-F248-11E8-B48F-1D18A9856A87
last_name: Higginbotham
orcid: 0000-0003-2607-2363
- first_name: N S
full_name: Kampel, N S
last_name: Kampel
- first_name: Robert
full_name: Peterson, Robert
last_name: Peterson
- first_name: Katarina
full_name: Cicak, Katarina
last_name: Cicak
- first_name: Raymond
full_name: Simmonds, Raymond
last_name: Simmonds
- first_name: Cindy
full_name: Regal, Cindy
last_name: Regal
- first_name: Konrad
full_name: Lehnert, Konrad
last_name: Lehnert
citation:
ama: Menke T, Burns P, Higginbotham AP, et al. Reconfigurable re-entrant cavity
for wireless coupling to an electro-optomechanical device. Review of Scientific
Instruments. 2017;88(9). doi:10.1063/1.5000973
apa: Menke, T., Burns, P., Higginbotham, A. P., Kampel, N. S., Peterson, R., Cicak,
K., … Lehnert, K. (2017). Reconfigurable re-entrant cavity for wireless coupling
to an electro-optomechanical device. Review of Scientific Instruments.
American Institute of Physics. https://doi.org/10.1063/1.5000973
chicago: Menke, Tim, Peter Burns, Andrew P Higginbotham, N S Kampel, Robert Peterson,
Katarina Cicak, Raymond Simmonds, Cindy Regal, and Konrad Lehnert. “Reconfigurable
Re-Entrant Cavity for Wireless Coupling to an Electro-Optomechanical Device.”
Review of Scientific Instruments. American Institute of Physics, 2017.
https://doi.org/10.1063/1.5000973.
ieee: T. Menke et al., “Reconfigurable re-entrant cavity for wireless coupling
to an electro-optomechanical device,” Review of Scientific Instruments,
vol. 88, no. 9. American Institute of Physics, 2017.
ista: Menke T, Burns P, Higginbotham AP, Kampel NS, Peterson R, Cicak K, Simmonds
R, Regal C, Lehnert K. 2017. Reconfigurable re-entrant cavity for wireless coupling
to an electro-optomechanical device. Review of Scientific Instruments. 88(9),
094701.
mla: Menke, Tim, et al. “Reconfigurable Re-Entrant Cavity for Wireless Coupling
to an Electro-Optomechanical Device.” Review of Scientific Instruments,
vol. 88, no. 9, 094701, American Institute of Physics, 2017, doi:10.1063/1.5000973.
short: T. Menke, P. Burns, A.P. Higginbotham, N.S. Kampel, R. Peterson, K. Cicak,
R. Simmonds, C. Regal, K. Lehnert, Review of Scientific Instruments 88 (2017).
date_created: 2018-12-11T11:44:35Z
date_published: 2017-09-08T00:00:00Z
date_updated: 2021-01-12T08:21:59Z
day: '08'
doi: 10.1063/1.5000973
extern: '1'
external_id:
arxiv:
- '1703.06470'
pmid:
- '28964202'
intvolume: ' 88'
issue: '9'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1703.06470
month: '09'
oa: 1
oa_version: Preprint
pmid: 1
publication: Review of Scientific Instruments
publication_status: published
publisher: American Institute of Physics
publist_id: '7961'
quality_controlled: '1'
status: public
title: Reconfigurable re-entrant cavity for wireless coupling to an electro-optomechanical
device
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 88
year: '2017'
...
---
_id: '934'
abstract:
- lang: eng
text: During puberty, the mouse mammary gland develops into a highly branched epithelial
network. Owing to the absence of exclusive stem cell markers, the location, multiplicity,
dynamics and fate of mammary stem cells (MaSCs), which drive branching morphogenesis,
are unknown. Here we show that morphogenesis is driven by proliferative terminal
end buds that terminate or bifurcate with near equal probability, in a stochastic
and time-invariant manner, leading to a heterogeneous epithelial network. We show
that the majority of terminal end bud cells function as highly proliferative,
lineage-committed MaSCs that are heterogeneous in their expression profile and
short-term contribution to ductal extension. Yet, through cell rearrangements
during terminal end bud bifurcation, each MaSC is able to contribute actively
to long-term growth. Our study shows that the behaviour of MaSCs is not directly
linked to a single expression profile. Instead, morphogenesis relies upon lineage-restricted
heterogeneous MaSC populations that function as single equipotent pools in the
long term.
author:
- first_name: Colinda
full_name: Scheele, Colinda
last_name: Scheele
- first_name: Edouard B
full_name: Hannezo, Edouard B
id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
last_name: Hannezo
orcid: 0000-0001-6005-1561
- first_name: Mauro
full_name: Muraro, Mauro
last_name: Muraro
- first_name: Anoek
full_name: Zomer, Anoek
last_name: Zomer
- first_name: Nathalia
full_name: Langedijk, Nathalia
last_name: Langedijk
- first_name: Alexander
full_name: Van Oudenaarden, Alexander
last_name: Van Oudenaarden
- first_name: Benjamin
full_name: Simons, Benjamin
last_name: Simons
- first_name: Jacco
full_name: Van Rheenen, Jacco
last_name: Van Rheenen
citation:
ama: Scheele C, Hannezo EB, Muraro M, et al. Identity and dynamics of mammary stem
cells during branching morphogenesis. Nature. 2017;542(7641):313-317. doi:10.1038/nature21046
apa: Scheele, C., Hannezo, E. B., Muraro, M., Zomer, A., Langedijk, N., Van Oudenaarden,
A., … Van Rheenen, J. (2017). Identity and dynamics of mammary stem cells during
branching morphogenesis. Nature. Nature Publishing Group. https://doi.org/10.1038/nature21046
chicago: Scheele, Colinda, Edouard B Hannezo, Mauro Muraro, Anoek Zomer, Nathalia
Langedijk, Alexander Van Oudenaarden, Benjamin Simons, and Jacco Van Rheenen.
“Identity and Dynamics of Mammary Stem Cells during Branching Morphogenesis.”
Nature. Nature Publishing Group, 2017. https://doi.org/10.1038/nature21046.
ieee: C. Scheele et al., “Identity and dynamics of mammary stem cells during
branching morphogenesis,” Nature, vol. 542, no. 7641. Nature Publishing
Group, pp. 313–317, 2017.
ista: Scheele C, Hannezo EB, Muraro M, Zomer A, Langedijk N, Van Oudenaarden A,
Simons B, Van Rheenen J. 2017. Identity and dynamics of mammary stem cells during
branching morphogenesis. Nature. 542(7641), 313–317.
mla: Scheele, Colinda, et al. “Identity and Dynamics of Mammary Stem Cells during
Branching Morphogenesis.” Nature, vol. 542, no. 7641, Nature Publishing
Group, 2017, pp. 313–17, doi:10.1038/nature21046.
short: C. Scheele, E.B. Hannezo, M. Muraro, A. Zomer, N. Langedijk, A. Van Oudenaarden,
B. Simons, J. Van Rheenen, Nature 542 (2017) 313–317.
date_created: 2018-12-11T11:49:17Z
date_published: 2017-02-16T00:00:00Z
date_updated: 2021-01-12T08:22:01Z
day: '16'
doi: 10.1038/nature21046
extern: '1'
intvolume: ' 542'
issue: '7641'
language:
- iso: eng
month: '02'
oa_version: None
page: 313 - 317
publication: Nature
publication_identifier:
issn:
- '00280836'
publication_status: published
publisher: Nature Publishing Group
publist_id: '6505'
quality_controlled: '1'
status: public
title: Identity and dynamics of mammary stem cells during branching morphogenesis
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 542
year: '2017'
...
---
_id: '936'
abstract:
- lang: eng
text: Homeostatic replacement of epithelial cells from basal precursors is a multistep
process involving progenitor cell specification, radial intercalation and, finally,
apical surface emergence. Recent data demonstrate that actin-based pushing under
the control of the formin protein Fmn1 drives apical emergence in nascent multiciliated
epithelial cells (MCCs), but little else is known about this actin network or
the control of Fmn1. Here, we explore the role of the small GTPase RhoA in MCC
apical emergence. Disruption of RhoA function reduced the rate of apical surface
expansion and decreased the final size of the apical domain. Analysis of cell
shapes suggests that RhoA alters the balance of forces exerted on the MCC apical
surface. Finally, quantitative time-lapse imaging and fluorescence recovery after
photobleaching studies argue that RhoA works in concert with Fmn1 to control assembly
of the specialized apical actin network in MCCs. These data provide new molecular
insights into epithelial apical surface assembly and could also shed light on
mechanisms of apical lumen formation
author:
- first_name: Jakub
full_name: Sedzinski, Jakub
last_name: Sedzinski
- first_name: Edouard B
full_name: Hannezo, Edouard B
id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
last_name: Hannezo
orcid: 0000-0001-6005-1561
- first_name: Fan
full_name: Tu, Fan
last_name: Tu
- first_name: Maté
full_name: Biro, Maté
last_name: Biro
- first_name: John
full_name: Wallingford, John
last_name: Wallingford
citation:
ama: Sedzinski J, Hannezo EB, Tu F, Biro M, Wallingford J. RhoA regulates actin
network dynamics during apical surface emergence in multiciliated epithelial cells
. Journal of Cell Science. 2017;130(5). doi:10.1242/jcs.202234
apa: Sedzinski, J., Hannezo, E. B., Tu, F., Biro, M., & Wallingford, J. (2017).
RhoA regulates actin network dynamics during apical surface emergence in multiciliated
epithelial cells . Journal of Cell Science. Company of Biologists. https://doi.org/10.1242/jcs.202234
chicago: Sedzinski, Jakub, Edouard B Hannezo, Fan Tu, Maté Biro, and John Wallingford.
“RhoA Regulates Actin Network Dynamics during Apical Surface Emergence in Multiciliated
Epithelial Cells .” Journal of Cell Science. Company of Biologists, 2017.
https://doi.org/10.1242/jcs.202234.
ieee: J. Sedzinski, E. B. Hannezo, F. Tu, M. Biro, and J. Wallingford, “RhoA regulates
actin network dynamics during apical surface emergence in multiciliated epithelial
cells ,” Journal of Cell Science, vol. 130, no. 5. Company of Biologists,
2017.
ista: Sedzinski J, Hannezo EB, Tu F, Biro M, Wallingford J. 2017. RhoA regulates
actin network dynamics during apical surface emergence in multiciliated epithelial
cells . Journal of Cell Science. 130(5).
mla: Sedzinski, Jakub, et al. “RhoA Regulates Actin Network Dynamics during Apical
Surface Emergence in Multiciliated Epithelial Cells .” Journal of Cell Science,
vol. 130, no. 5, Company of Biologists, 2017, doi:10.1242/jcs.202234.
short: J. Sedzinski, E.B. Hannezo, F. Tu, M. Biro, J. Wallingford, Journal of Cell
Science 130 (2017).
date_created: 2018-12-11T11:49:17Z
date_published: 2017-01-01T00:00:00Z
date_updated: 2021-01-12T08:22:02Z
day: '01'
doi: 10.1242/jcs.202234
extern: '1'
intvolume: ' 130'
issue: '5'
language:
- iso: eng
month: '01'
oa_version: None
publication: Journal of Cell Science
publication_status: published
publisher: Company of Biologists
publist_id: '6507'
quality_controlled: '1'
status: public
title: 'RhoA regulates actin network dynamics during apical surface emergence in multiciliated
epithelial cells '
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 130
year: '2017'
...
---
_id: '937'
abstract:
- lang: eng
text: During epithelial cytokinesis, the remodelling of adhesive cell-cell contacts
between the dividing cell and its neighbours has profound implications for the
integrity, arrangement and morphogenesis of proliferative tissues. In both vertebrates
and invertebrates, this remodelling requires the activity of non-muscle myosin
II (MyoII) in the interphasic cells neighbouring the dividing cell. However, the
mechanisms that coordinate cytokinesis and MyoII activity in the neighbours are
unknown. Here we show that in the Drosophila notum epithelium, each cell division
is associated with a mechanosensing and transmission event that controls MyoII
dynamics in neighbouring cells. We find that the ring pulling forces promote local
junction elongation, which results in local E-cadherin dilution at the ingressing
adherens junction. In turn, the reduction in E-cadherin concentration and the
contractility of the neighbouring cells promote self-organized actomyosin flows,
ultimately leading to accumulation of MyoII at the base of the ingressing junction.
Although force transduction has been extensively studied in the context of adherens
junction reinforcement to stabilize adhesive cell-cell contacts, we propose an
alternative mechanosensing mechanism that coordinates actomyosin dynamics between
epithelial cells and sustains the remodelling of the adherens junction in response
to mechanical forces.
author:
- first_name: Diana
full_name: Pinheiro, Diana
last_name: Pinheiro
- first_name: Edouard B
full_name: Hannezo, Edouard B
id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
last_name: Hannezo
orcid: 0000-0001-6005-1561
- first_name: Sophie
full_name: Herszterg, Sophie
last_name: Herszterg
- first_name: Floris
full_name: Bosveld, Floris
last_name: Bosveld
- first_name: Isabelle
full_name: Gaugué, Isabelle
last_name: Gaugué
- first_name: Maria
full_name: Balakireva, Maria
last_name: Balakireva
- first_name: Zhimin
full_name: Wang, Zhimin
last_name: Wang
- first_name: Inês
full_name: Cristo, Inês
last_name: Cristo
- first_name: Stéphane
full_name: Rigaud, Stéphane
last_name: Rigaud
- first_name: Olga
full_name: Markova, Olga
last_name: Markova
- first_name: Yohanns
full_name: Bellaïche, Yohanns
last_name: Bellaïche
citation:
ama: Pinheiro D, Hannezo EB, Herszterg S, et al. Transmission of cytokinesis forces
via E cadherin dilution and actomyosin flows. Nature. 2017;545(7652):103-107.
doi:10.1038/nature22041
apa: Pinheiro, D., Hannezo, E. B., Herszterg, S., Bosveld, F., Gaugué, I., Balakireva,
M., … Bellaïche, Y. (2017). Transmission of cytokinesis forces via E cadherin
dilution and actomyosin flows. Nature. Nature Publishing Group. https://doi.org/10.1038/nature22041
chicago: Pinheiro, Diana, Edouard B Hannezo, Sophie Herszterg, Floris Bosveld, Isabelle
Gaugué, Maria Balakireva, Zhimin Wang, et al. “Transmission of Cytokinesis Forces
via E Cadherin Dilution and Actomyosin Flows.” Nature. Nature Publishing
Group, 2017. https://doi.org/10.1038/nature22041.
ieee: D. Pinheiro et al., “Transmission of cytokinesis forces via E cadherin
dilution and actomyosin flows,” Nature, vol. 545, no. 7652. Nature Publishing
Group, pp. 103–107, 2017.
ista: Pinheiro D, Hannezo EB, Herszterg S, Bosveld F, Gaugué I, Balakireva M, Wang
Z, Cristo I, Rigaud S, Markova O, Bellaïche Y. 2017. Transmission of cytokinesis
forces via E cadherin dilution and actomyosin flows. Nature. 545(7652), 103–107.
mla: Pinheiro, Diana, et al. “Transmission of Cytokinesis Forces via E Cadherin
Dilution and Actomyosin Flows.” Nature, vol. 545, no. 7652, Nature Publishing
Group, 2017, pp. 103–07, doi:10.1038/nature22041.
short: D. Pinheiro, E.B. Hannezo, S. Herszterg, F. Bosveld, I. Gaugué, M. Balakireva,
Z. Wang, I. Cristo, S. Rigaud, O. Markova, Y. Bellaïche, Nature 545 (2017) 103–107.
date_created: 2018-12-11T11:49:18Z
date_published: 2017-05-04T00:00:00Z
date_updated: 2021-01-12T08:22:02Z
day: '04'
doi: 10.1038/nature22041
extern: '1'
intvolume: ' 545'
issue: '7652'
language:
- iso: eng
month: '05'
oa_version: None
page: 103 - 107
publication: Nature
publication_identifier:
issn:
- '00280836'
publication_status: published
publisher: Nature Publishing Group
publist_id: '6504'
quality_controlled: '1'
status: public
title: Transmission of cytokinesis forces via E cadherin dilution and actomyosin flows
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 545
year: '2017'
...
---
_id: '938'
abstract:
- lang: eng
text: The thesis encompasses several topics of plant cell biology which were studied
in the model plant Arabidopsis thaliana. Chapter 1 concerns the plant hormone
auxin and its polar transport through cells and tissues. The highly controlled,
directional transport of auxin is facilitated by plasma membrane-localized transporters.
Transporters from the PIN family direct auxin transport due to their polarized
localizations at cell membranes. Substantial effort has been put into research
on cellular trafficking of PIN proteins, which is thought to underlie their polar
distribution. I participated in a forward genetic screen aimed at identifying
novel regulators of PIN polarity. The screen yielded several genes which may be
involved in PIN polarity regulation or participate in polar auxin transport by
other means. Chapter 2 focuses on the endomembrane system, with particular attention
to clathrin-mediated endocytosis. The project started with identification of several
proteins that interact with clathrin light chains. Among them, I focused on two
putative homologues of auxilin, which in non-plant systems is an endocytotic factor
known for uncoating clathrin-coated vesicles in the final step of endocytosis.
The body of my work consisted of an in-depth characterization of transgenic A.
thaliana lines overexpressing these putative auxilins in an inducible manner.
Overexpression of these proteins leads to an inhibition of endocytosis, as documented
by imaging of cargoes and clathrin-related endocytic machinery. An extension of
this work is an investigation into a concept of homeostatic regulation acting
between distinct transport processes in the endomembrane system. With auxilin
overexpressing lines, where endocytosis is blocked specifically, I made observations
on the mutual relationship between two opposite trafficking processes of secretion
and endocytosis. In Chapter 3, I analyze cortical microtubule arrays and their
relationship to auxin signaling and polarized growth in elongating cells. In plants,
microtubules are organized into arrays just below the plasma membrane, and it
is thought that their function is to guide membrane-docked cellulose synthase
complexes. These, in turn, influence cell wall structure and cell shape by directed
deposition of cellulose fibres. In elongating cells, cortical microtubule arrays
are able to reorient in relation to long cell axis, and these reorientations have
been linked to cell growth and to signaling of growth-regulating factors such
as auxin or light. In this chapter, I am addressing the causal relationship between
microtubule array reorientation, growth, and auxin signaling. I arrive at a model
where array reorientation is not guided by auxin directly, but instead is only
controlled by growth, which, in turn, is regulated by auxin.
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Maciek
full_name: Adamowski, Maciek
id: 45F536D2-F248-11E8-B48F-1D18A9856A87
last_name: Adamowski
orcid: 0000-0001-6463-5257
citation:
ama: Adamowski M. Investigations into cell polarity and trafficking in the plant
model Arabidopsis thaliana . 2017. doi:10.15479/AT:ISTA:th_842
apa: Adamowski, M. (2017). Investigations into cell polarity and trafficking
in the plant model Arabidopsis thaliana . Institute of Science and Technology
Austria. https://doi.org/10.15479/AT:ISTA:th_842
chicago: Adamowski, Maciek. “Investigations into Cell Polarity and Trafficking in
the Plant Model Arabidopsis Thaliana .” Institute of Science and Technology Austria,
2017. https://doi.org/10.15479/AT:ISTA:th_842.
ieee: M. Adamowski, “Investigations into cell polarity and trafficking in the plant
model Arabidopsis thaliana ,” Institute of Science and Technology Austria, 2017.
ista: Adamowski M. 2017. Investigations into cell polarity and trafficking in the
plant model Arabidopsis thaliana . Institute of Science and Technology Austria.
mla: Adamowski, Maciek. Investigations into Cell Polarity and Trafficking in
the Plant Model Arabidopsis Thaliana . Institute of Science and Technology
Austria, 2017, doi:10.15479/AT:ISTA:th_842.
short: M. Adamowski, Investigations into Cell Polarity and Trafficking in the Plant
Model Arabidopsis Thaliana , Institute of Science and Technology Austria, 2017.
date_created: 2018-12-11T11:49:18Z
date_published: 2017-06-02T00:00:00Z
date_updated: 2023-09-07T12:06:09Z
day: '02'
ddc:
- '581'
- '583'
- '580'
degree_awarded: PhD
department:
- _id: JiFr
doi: 10.15479/AT:ISTA:th_842
file:
- access_level: closed
checksum: 193425764d9aaaed3ac57062a867b315
content_type: application/vnd.openxmlformats-officedocument.wordprocessingml.document
creator: dernst
date_created: 2019-04-05T09:03:20Z
date_updated: 2020-07-14T12:48:15Z
file_id: '6215'
file_name: 2017_Adamowski-Thesis_Source.docx
file_size: 46903863
relation: source_file
- access_level: open_access
checksum: df5ab01be81f821e1b958596a1ec8d21
content_type: application/pdf
creator: dernst
date_created: 2019-04-05T09:03:19Z
date_updated: 2020-07-14T12:48:15Z
file_id: '6216'
file_name: 2017_Adamowski-Thesis.pdf
file_size: 8698888
relation: main_file
file_date_updated: 2020-07-14T12:48:15Z
has_accepted_license: '1'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: '117'
publication_identifier:
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
publist_id: '6483'
pubrep_id: '842'
related_material:
record:
- id: '1591'
relation: part_of_dissertation
status: public
status: public
supervisor:
- first_name: Jiří
full_name: Friml, Jiří
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
title: 'Investigations into cell polarity and trafficking in the plant model Arabidopsis
thaliana '
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2017'
...
---
_id: '939'
abstract:
- lang: eng
text: We reveal the existence of continuous families of guided single-mode solitons
in planar waveguides with weakly nonlinear active core and absorbing boundaries.
Stable propagation of TE and TM-polarized solitons is accompanied by attenuation
of all other modes, i.e., the waveguide features properties of conservative and
dissipative systems. If the linear spectrum of the waveguide possesses exceptional
points, which occurs in the case of TM polarization, an originally focusing (defocusing)
material nonlinearity may become effectively defocusing (focusing). This occurs
due to the geometric phase of the carried eigenmode when the surface impedance
encircles the exceptional point. In its turn, the change of the effective nonlinearity
ensures the existence of dark (bright) solitons in spite of focusing (defocusing)
Kerr nonlinearity of the core. The existence of an exceptional point can also
result in anomalous enhancement of the effective nonlinearity. In terms of practical
applications, the nonlinearity of the reported waveguide can be manipulated by
controlling the properties of the absorbing cladding.
article_number: '033905'
article_processing_charge: No
author:
- first_name: Bikashkali
full_name: Midya, Bikashkali
id: 456187FC-F248-11E8-B48F-1D18A9856A87
last_name: Midya
- first_name: Vladimir
full_name: Konotop, Vladimir
last_name: Konotop
citation:
ama: 'Midya B, Konotop V. Waveguides with absorbing boundaries: Nonlinearity controlled
by an exceptional point and solitons. Physical Review Letters. 2017;119(3).
doi:10.1103/PhysRevLett.119.033905'
apa: 'Midya, B., & Konotop, V. (2017). Waveguides with absorbing boundaries:
Nonlinearity controlled by an exceptional point and solitons. Physical Review
Letters. American Physical Society. https://doi.org/10.1103/PhysRevLett.119.033905'
chicago: 'Midya, Bikashkali, and Vladimir Konotop. “Waveguides with Absorbing Boundaries:
Nonlinearity Controlled by an Exceptional Point and Solitons.” Physical Review
Letters. American Physical Society, 2017. https://doi.org/10.1103/PhysRevLett.119.033905.'
ieee: 'B. Midya and V. Konotop, “Waveguides with absorbing boundaries: Nonlinearity
controlled by an exceptional point and solitons,” Physical Review Letters,
vol. 119, no. 3. American Physical Society, 2017.'
ista: 'Midya B, Konotop V. 2017. Waveguides with absorbing boundaries: Nonlinearity
controlled by an exceptional point and solitons. Physical Review Letters. 119(3),
033905.'
mla: 'Midya, Bikashkali, and Vladimir Konotop. “Waveguides with Absorbing Boundaries:
Nonlinearity Controlled by an Exceptional Point and Solitons.” Physical Review
Letters, vol. 119, no. 3, 033905, American Physical Society, 2017, doi:10.1103/PhysRevLett.119.033905.'
short: B. Midya, V. Konotop, Physical Review Letters 119 (2017).
date_created: 2018-12-11T11:49:18Z
date_published: 2017-07-18T00:00:00Z
date_updated: 2023-09-26T15:39:46Z
day: '18'
department:
- _id: MiLe
doi: 10.1103/PhysRevLett.119.033905
ec_funded: 1
external_id:
isi:
- '000405718200012'
intvolume: ' 119'
isi: 1
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: 'https://arxiv.org/abs/1706.04085 '
month: '07'
oa: 1
oa_version: Submitted Version
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: Physical Review Letters
publication_identifier:
issn:
- '00319007'
publication_status: published
publisher: American Physical Society
publist_id: '6481'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Waveguides with absorbing boundaries: Nonlinearity controlled by an exceptional
point and solitons'
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 119
year: '2017'
...
---
_id: '94'
abstract:
- lang: eng
text: We introduce a method for breaking Lorentz reciprocity based upon the noncommutation
of frequency conversion and delay. The method requires no magnetic materials or
resonant physics, allowing for the design of scalable and broadband nonreciprocal
circuits. With this approach, two types of gyrators - universal building blocks
for linear, nonreciprocal circuits - are constructed. Using one of these gyrators,
we create a circulator with >15 dB of isolation across the 5-9 GHz band. Our
designs may be readily extended to any platform with suitable frequency conversion
elements, including semiconducting devices for telecommunication or an on-chip
superconducting implementation for quantum information processing.
article_number: '147703'
arxiv: 1
author:
- first_name: Eric
full_name: Rosenthal, Eric
last_name: Rosenthal
- first_name: Benjamin
full_name: Chapman, Benjamin
last_name: Chapman
- first_name: Andrew P
full_name: Higginbotham, Andrew P
id: 4AD6785A-F248-11E8-B48F-1D18A9856A87
last_name: Higginbotham
orcid: 0000-0003-2607-2363
- first_name: Joseph
full_name: Kerckhoff, Joseph
last_name: Kerckhoff
- first_name: Konrad
full_name: Lehnert, Konrad
last_name: Lehnert
citation:
ama: Rosenthal E, Chapman B, Higginbotham AP, Kerckhoff J, Lehnert K. Breaking Lorentz
reciprocity with frequency conversion and delay. APS Physics, Physical Review
Letters. 2017;119(14). doi:10.1103/PhysRevLett.119.147703
apa: Rosenthal, E., Chapman, B., Higginbotham, A. P., Kerckhoff, J., & Lehnert,
K. (2017). Breaking Lorentz reciprocity with frequency conversion and delay. APS
Physics, Physical Review Letters. American Physical Society. https://doi.org/10.1103/PhysRevLett.119.147703
chicago: Rosenthal, Eric, Benjamin Chapman, Andrew P Higginbotham, Joseph Kerckhoff,
and Konrad Lehnert. “Breaking Lorentz Reciprocity with Frequency Conversion and
Delay.” APS Physics, Physical Review Letters. American Physical Society,
2017. https://doi.org/10.1103/PhysRevLett.119.147703.
ieee: E. Rosenthal, B. Chapman, A. P. Higginbotham, J. Kerckhoff, and K. Lehnert,
“Breaking Lorentz reciprocity with frequency conversion and delay,” APS Physics,
Physical Review Letters, vol. 119, no. 14. American Physical Society, 2017.
ista: Rosenthal E, Chapman B, Higginbotham AP, Kerckhoff J, Lehnert K. 2017. Breaking
Lorentz reciprocity with frequency conversion and delay. APS Physics, Physical
Review Letters. 119(14), 147703.
mla: Rosenthal, Eric, et al. “Breaking Lorentz Reciprocity with Frequency Conversion
and Delay.” APS Physics, Physical Review Letters, vol. 119, no. 14, 147703,
American Physical Society, 2017, doi:10.1103/PhysRevLett.119.147703.
short: E. Rosenthal, B. Chapman, A.P. Higginbotham, J. Kerckhoff, K. Lehnert, APS
Physics, Physical Review Letters 119 (2017).
date_created: 2018-12-11T11:44:35Z
date_published: 2017-10-06T00:00:00Z
date_updated: 2021-01-12T08:22:04Z
day: '06'
doi: 10.1103/PhysRevLett.119.147703
extern: '1'
external_id:
arxiv:
- '1705.09548'
intvolume: ' 119'
issue: '14'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1705.09548
month: '10'
oa: 1
oa_version: Submitted Version
publication: APS Physics, Physical Review Letters
publication_status: published
publisher: American Physical Society
publist_id: '7960'
quality_controlled: '1'
status: public
title: Breaking Lorentz reciprocity with frequency conversion and delay
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 119
year: '2017'
...
---
_id: '941'
abstract:
- lang: eng
text: 'Recently there has been a proliferation of automated program repair (APR)
techniques, targeting various programming languages. Such techniques can be generally
classified into two families: syntactic- and semantics-based. Semantics-based
APR, on which we focus, typically uses symbolic execution to infer semantic constraints
and then program synthesis to construct repairs conforming to them. While syntactic-based
APR techniques have been shown successful on bugs in real-world programs written
in both C and Java, semantics-based APR techniques mostly target C programs. This
leaves empirical comparisons of the APR families not fully explored, and developers
without a Java-based semantics APR technique. We present JFix, a semantics-based
APR framework that targets Java, and an associated Eclipse plugin. JFix is implemented
atop Symbolic PathFinder, a well-known symbolic execution engine for Java programs.
It extends one particular APR technique (Angelix), and is designed to be sufficiently
generic to support a variety of such techniques. We demonstrate that semantics-based
APR can indeed efficiently and effectively repair a variety of classes of bugs
in large real-world Java programs. This supports our claim that the framework
can both support developers seeking semantics-based repair of bugs in Java programs,
as well as enable larger scale empirical studies comparing syntactic- and semantics-based
APR targeting Java. The demonstration of our tool is available via the project
website at: https://xuanbachle.github.io/semanticsrepair/ '
author:
- first_name: Xuan
full_name: Le, Xuan
last_name: Le
- first_name: Duc Hiep
full_name: Chu, Duc Hiep
id: 3598E630-F248-11E8-B48F-1D18A9856A87
last_name: Chu
- first_name: David
full_name: Lo, David
last_name: Lo
- first_name: Claire
full_name: Le Goues, Claire
last_name: Le Goues
- first_name: Willem
full_name: Visser, Willem
last_name: Visser
citation:
ama: 'Le X, Chu DH, Lo D, Le Goues C, Visser W. JFIX: Semantics-based repair of
Java programs via symbolic PathFinder. In: Proceedings of the 26th ACM SIGSOFT
International Symposium on Software Testing and Analysis. ACM; 2017:376-379.
doi:10.1145/3092703.3098225'
apa: 'Le, X., Chu, D. H., Lo, D., Le Goues, C., & Visser, W. (2017). JFIX: Semantics-based
repair of Java programs via symbolic PathFinder. In Proceedings of the 26th
ACM SIGSOFT International Symposium on Software Testing and Analysis (pp.
376–379). Santa Barbara, CA, United States: ACM. https://doi.org/10.1145/3092703.3098225'
chicago: 'Le, Xuan, Duc Hiep Chu, David Lo, Claire Le Goues, and Willem Visser.
“JFIX: Semantics-Based Repair of Java Programs via Symbolic PathFinder.” In Proceedings
of the 26th ACM SIGSOFT International Symposium on Software Testing and Analysis,
376–79. ACM, 2017. https://doi.org/10.1145/3092703.3098225.'
ieee: 'X. Le, D. H. Chu, D. Lo, C. Le Goues, and W. Visser, “JFIX: Semantics-based
repair of Java programs via symbolic PathFinder,” in Proceedings of the 26th
ACM SIGSOFT International Symposium on Software Testing and Analysis, Santa
Barbara, CA, United States, 2017, pp. 376–379.'
ista: 'Le X, Chu DH, Lo D, Le Goues C, Visser W. 2017. JFIX: Semantics-based repair
of Java programs via symbolic PathFinder. Proceedings of the 26th ACM SIGSOFT
International Symposium on Software Testing and Analysis. ISSTA: International
Symposium on Software Testing and Analysis, 376–379.'
mla: 'Le, Xuan, et al. “JFIX: Semantics-Based Repair of Java Programs via Symbolic
PathFinder.” Proceedings of the 26th ACM SIGSOFT International Symposium on
Software Testing and Analysis, ACM, 2017, pp. 376–79, doi:10.1145/3092703.3098225.'
short: X. Le, D.H. Chu, D. Lo, C. Le Goues, W. Visser, in:, Proceedings of the 26th
ACM SIGSOFT International Symposium on Software Testing and Analysis, ACM, 2017,
pp. 376–379.
conference:
end_date: 2017-07-14
location: Santa Barbara, CA, United States
name: 'ISSTA: International Symposium on Software Testing and Analysis'
start_date: 2017-07-10
date_created: 2018-12-11T11:49:19Z
date_published: 2017-07-10T00:00:00Z
date_updated: 2021-01-12T08:22:05Z
day: '10'
department:
- _id: ToHe
doi: 10.1145/3092703.3098225
language:
- iso: eng
month: '07'
oa_version: None
page: '376 - 379 '
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z211
name: The Wittgenstein Prize
publication: Proceedings of the 26th ACM SIGSOFT International Symposium on Software
Testing and Analysis
publication_status: published
publisher: ACM
publist_id: '6478'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'JFIX: Semantics-based repair of Java programs via symbolic PathFinder'
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
year: '2017'
...
---
_id: '942'
abstract:
- lang: eng
text: 'A notable class of techniques for automatic program repair is known as semantics-based.
Such techniques, e.g., Angelix, infer semantic specifications via symbolic execution,
and then use program synthesis to construct new code that satisfies those inferred
specifications. However, the obtained specifications are naturally incomplete,
leaving the synthesis engine with a difficult task of synthesizing a general solution
from a sparse space of many possible solutions that are consistent with the provided
specifications but that do not necessarily generalize. We present S3, a new repair
synthesis engine that leverages programming-by-examples methodology to synthesize
high-quality bug repairs. The novelty in S3 that allows it to tackle the sparse
search space to create more general repairs is three-fold: (1) A systematic way
to customize and constrain the syntactic search space via a domain-specific language,
(2) An efficient enumeration-based search strategy over the constrained search
space, and (3) A number of ranking features based on measures of the syntactic
and semantic distances between candidate solutions and the original buggy program.
We compare S3’s repair effectiveness with state-of-the-art synthesis engines Angelix,
Enumerative, and CVC4. S3 can successfully and correctly fix at least three times
more bugs than the best baseline on datasets of 52 bugs in small programs, and
100 bugs in real-world large programs. '
article_processing_charge: No
author:
- first_name: Xuan
full_name: Le, Xuan
last_name: Le
- first_name: Duc Hiep
full_name: Chu, Duc Hiep
id: 3598E630-F248-11E8-B48F-1D18A9856A87
last_name: Chu
- first_name: David
full_name: Lo, David
last_name: Lo
- first_name: Claire
full_name: Le Goues, Claire
last_name: Le Goues
- first_name: Willem
full_name: Visser, Willem
last_name: Visser
citation:
ama: 'Le X, Chu DH, Lo D, Le Goues C, Visser W. S3: Syntax- and semantic-guided
repair synthesis via programming by examples. In: Vol F130154. ACM; 2017:593-604.
doi:10.1145/3106237.3106309'
apa: 'Le, X., Chu, D. H., Lo, D., Le Goues, C., & Visser, W. (2017). S3: Syntax-
and semantic-guided repair synthesis via programming by examples (Vol. F130154,
pp. 593–604). Presented at the FSE: Foundations of Software Engineering, Paderborn,
Germany: ACM. https://doi.org/10.1145/3106237.3106309'
chicago: 'Le, Xuan, Duc Hiep Chu, David Lo, Claire Le Goues, and Willem Visser.
“S3: Syntax- and Semantic-Guided Repair Synthesis via Programming by Examples,”
F130154:593–604. ACM, 2017. https://doi.org/10.1145/3106237.3106309.'
ieee: 'X. Le, D. H. Chu, D. Lo, C. Le Goues, and W. Visser, “S3: Syntax- and semantic-guided
repair synthesis via programming by examples,” presented at the FSE: Foundations
of Software Engineering, Paderborn, Germany, 2017, vol. F130154, pp. 593–604.'
ista: 'Le X, Chu DH, Lo D, Le Goues C, Visser W. 2017. S3: Syntax- and semantic-guided
repair synthesis via programming by examples. FSE: Foundations of Software Engineering
vol. F130154, 593–604.'
mla: 'Le, Xuan, et al. S3: Syntax- and Semantic-Guided Repair Synthesis via Programming
by Examples. Vol. F130154, ACM, 2017, pp. 593–604, doi:10.1145/3106237.3106309.'
short: X. Le, D.H. Chu, D. Lo, C. Le Goues, W. Visser, in:, ACM, 2017, pp. 593–604.
conference:
end_date: 2017-09-08
location: Paderborn, Germany
name: 'FSE: Foundations of Software Engineering'
start_date: 2017-09-04
date_created: 2018-12-11T11:49:19Z
date_published: 2017-09-01T00:00:00Z
date_updated: 2023-09-26T15:38:36Z
day: '01'
department:
- _id: ToHe
doi: 10.1145/3106237.3106309
external_id:
isi:
- '000414279300055'
isi: 1
language:
- iso: eng
month: '09'
oa_version: None
page: 593 - 604
project:
- _id: 25F5A88A-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11402-N23
name: Moderne Concurrency Paradigms
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z211
name: The Wittgenstein Prize
publication_identifier:
isbn:
- 978-145035105-8
publication_status: published
publisher: ACM
publist_id: '6477'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'S3: Syntax- and semantic-guided repair synthesis via programming by examples'
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: F130154
year: '2017'
...
---
_id: '943'
abstract:
- lang: eng
text: Like many developing tissues, the vertebrate neural tube is patterned by antiparallel
morphogen gradients. To understand how these inputs are interpreted, we measured
morphogen signaling and target gene expression in mouse embryos and chick ex vivo
assays. From these data, we derived and validated a characteristic decoding map
that relates morphogen input to the positional identity of neural progenitors.
Analysis of the observed responses indicates that the underlying interpretation
strategy minimizes patterning errors in response to the joint input of noisy opposing
gradients. We reverse-engineered a transcriptional network that provides a mechanistic
basis for the observed cell fate decisions and accounts for the precision and
dynamics of pattern formation. Together, our data link opposing gradient dynamics
in a growing tissue to precise pattern formation.
article_processing_charge: No
author:
- first_name: Marcin P
full_name: Zagórski, Marcin P
id: 343DA0DC-F248-11E8-B48F-1D18A9856A87
last_name: Zagórski
orcid: 0000-0001-7896-7762
- first_name: Yoji
full_name: Tabata, Yoji
last_name: Tabata
- first_name: Nathalie
full_name: Brandenberg, Nathalie
last_name: Brandenberg
- first_name: Matthias
full_name: Lutolf, Matthias
last_name: Lutolf
- first_name: Gasper
full_name: Tkacik, Gasper
id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
last_name: Tkacik
orcid: 0000-0002-6699-1455
- first_name: Tobias
full_name: Bollenbach, Tobias
last_name: Bollenbach
- first_name: James
full_name: Briscoe, James
last_name: Briscoe
- first_name: Anna
full_name: Kicheva, Anna
id: 3959A2A0-F248-11E8-B48F-1D18A9856A87
last_name: Kicheva
orcid: 0000-0003-4509-4998
citation:
ama: Zagórski MP, Tabata Y, Brandenberg N, et al. Decoding of position in the developing
neural tube from antiparallel morphogen gradients. Science. 2017;356(6345):1379-1383.
doi:10.1126/science.aam5887
apa: Zagórski, M. P., Tabata, Y., Brandenberg, N., Lutolf, M., Tkačik, G., Bollenbach,
T., … Kicheva, A. (2017). Decoding of position in the developing neural tube from
antiparallel morphogen gradients. Science. American Association for the
Advancement of Science. https://doi.org/10.1126/science.aam5887
chicago: Zagórski, Marcin P, Yoji Tabata, Nathalie Brandenberg, Matthias Lutolf,
Gašper Tkačik, Tobias Bollenbach, James Briscoe, and Anna Kicheva. “Decoding of
Position in the Developing Neural Tube from Antiparallel Morphogen Gradients.”
Science. American Association for the Advancement of Science, 2017. https://doi.org/10.1126/science.aam5887.
ieee: M. P. Zagórski et al., “Decoding of position in the developing neural
tube from antiparallel morphogen gradients,” Science, vol. 356, no. 6345.
American Association for the Advancement of Science, pp. 1379–1383, 2017.
ista: Zagórski MP, Tabata Y, Brandenberg N, Lutolf M, Tkačik G, Bollenbach T, Briscoe
J, Kicheva A. 2017. Decoding of position in the developing neural tube from antiparallel
morphogen gradients. Science. 356(6345), 1379–1383.
mla: Zagórski, Marcin P., et al. “Decoding of Position in the Developing Neural
Tube from Antiparallel Morphogen Gradients.” Science, vol. 356, no. 6345,
American Association for the Advancement of Science, 2017, pp. 1379–83, doi:10.1126/science.aam5887.
short: M.P. Zagórski, Y. Tabata, N. Brandenberg, M. Lutolf, G. Tkačik, T. Bollenbach,
J. Briscoe, A. Kicheva, Science 356 (2017) 1379–1383.
date_created: 2018-12-11T11:49:20Z
date_published: 2017-06-30T00:00:00Z
date_updated: 2023-09-26T15:38:05Z
day: '30'
department:
- _id: AnKi
- _id: GaTk
doi: 10.1126/science.aam5887
ec_funded: 1
external_id:
isi:
- '000404351500036'
pmid:
- '28663499'
intvolume: ' 356'
isi: 1
issue: '6345'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568706/
month: '06'
oa: 1
oa_version: Submitted Version
page: 1379 - 1383
pmid: 1
project:
- _id: 254E9036-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P28844-B27
name: Biophysics of information processing in gene regulation
- _id: B6FC0238-B512-11E9-945C-1524E6697425
call_identifier: H2020
grant_number: '680037'
name: Coordination of Patterning And Growth In the Spinal Cord
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
- _id: 2524F500-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '201439'
name: Developing High-Throughput Bioassays for Human Cancers in Zebrafish
publication: Science
publication_identifier:
issn:
- '00368075'
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '6474'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Decoding of position in the developing neural tube from antiparallel morphogen
gradients
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 356
year: '2017'
...
---
_id: '944'
abstract:
- lang: eng
text: The concerted production of neurons and glia by neural stem cells (NSCs) is
essential for neural circuit assembly. In the developing cerebral cortex, radial
glia progenitors (RGPs) generate nearly all neocortical neurons and certain glia
lineages. RGP proliferation behavior shows a high degree of non-stochasticity,
thus a deterministic characteristic of neuron and glia production. However, the
cellular and molecular mechanisms controlling RGP behavior and proliferation dynamics
in neurogenesis and glia generation remain unknown. By using mosaic analysis with
double markers (MADM)-based genetic paradigms enabling the sparse and global knockout
with unprecedented single-cell resolution, we identified Lgl1 as a critical regulatory
component. We uncover Lgl1-dependent tissue-wide community effects required for
embryonic cortical neurogenesis and novel cell-autonomous Lgl1 functions controlling
RGP-mediated glia genesis and postnatal NSC behavior. These results suggest that
NSC-mediated neuron and glia production is tightly regulated through the concerted
interplay of sequential Lgl1-dependent global and cell intrinsic mechanisms.
acknowledged_ssus:
- _id: Bio
- _id: PreCl
article_processing_charge: No
author:
- first_name: Robert J
full_name: Beattie, Robert J
id: 2E26DF60-F248-11E8-B48F-1D18A9856A87
last_name: Beattie
orcid: 0000-0002-8483-8753
- first_name: Maria P
full_name: Postiglione, Maria P
id: 2C67902A-F248-11E8-B48F-1D18A9856A87
last_name: Postiglione
- first_name: Laura
full_name: Burnett, Laura
id: 3B717F68-F248-11E8-B48F-1D18A9856A87
last_name: Burnett
orcid: 0000-0002-8937-410X
- first_name: Susanne
full_name: Laukoter, Susanne
id: 2D6B7A9A-F248-11E8-B48F-1D18A9856A87
last_name: Laukoter
orcid: 0000-0002-7903-3010
- first_name: Carmen
full_name: Streicher, Carmen
id: 36BCB99C-F248-11E8-B48F-1D18A9856A87
last_name: Streicher
- first_name: Florian
full_name: Pauler, Florian
id: 48EA0138-F248-11E8-B48F-1D18A9856A87
last_name: Pauler
orcid: 0000-0002-7462-0048
- first_name: Guanxi
full_name: Xiao, Guanxi
last_name: Xiao
- first_name: Olga
full_name: Klezovitch, Olga
last_name: Klezovitch
- first_name: Valeri
full_name: Vasioukhin, Valeri
last_name: Vasioukhin
- first_name: Troy
full_name: Ghashghaei, Troy
last_name: Ghashghaei
- first_name: Simon
full_name: Hippenmeyer, Simon
id: 37B36620-F248-11E8-B48F-1D18A9856A87
last_name: Hippenmeyer
orcid: 0000-0003-2279-1061
citation:
ama: Beattie RJ, Postiglione MP, Burnett L, et al. Mosaic analysis with double markers
reveals distinct sequential functions of Lgl1 in neural stem cells. Neuron.
2017;94(3):517-533.e3. doi:10.1016/j.neuron.2017.04.012
apa: Beattie, R. J., Postiglione, M. P., Burnett, L., Laukoter, S., Streicher, C.,
Pauler, F., … Hippenmeyer, S. (2017). Mosaic analysis with double markers reveals
distinct sequential functions of Lgl1 in neural stem cells. Neuron. Cell
Press. https://doi.org/10.1016/j.neuron.2017.04.012
chicago: Beattie, Robert J, Maria P Postiglione, Laura Burnett, Susanne Laukoter,
Carmen Streicher, Florian Pauler, Guanxi Xiao, et al. “Mosaic Analysis with Double
Markers Reveals Distinct Sequential Functions of Lgl1 in Neural Stem Cells.” Neuron.
Cell Press, 2017. https://doi.org/10.1016/j.neuron.2017.04.012.
ieee: R. J. Beattie et al., “Mosaic analysis with double markers reveals
distinct sequential functions of Lgl1 in neural stem cells,” Neuron, vol.
94, no. 3. Cell Press, p. 517–533.e3, 2017.
ista: Beattie RJ, Postiglione MP, Burnett L, Laukoter S, Streicher C, Pauler F,
Xiao G, Klezovitch O, Vasioukhin V, Ghashghaei T, Hippenmeyer S. 2017. Mosaic
analysis with double markers reveals distinct sequential functions of Lgl1 in
neural stem cells. Neuron. 94(3), 517–533.e3.
mla: Beattie, Robert J., et al. “Mosaic Analysis with Double Markers Reveals Distinct
Sequential Functions of Lgl1 in Neural Stem Cells.” Neuron, vol. 94, no.
3, Cell Press, 2017, p. 517–533.e3, doi:10.1016/j.neuron.2017.04.012.
short: R.J. Beattie, M.P. Postiglione, L. Burnett, S. Laukoter, C. Streicher, F.
Pauler, G. Xiao, O. Klezovitch, V. Vasioukhin, T. Ghashghaei, S. Hippenmeyer,
Neuron 94 (2017) 517–533.e3.
date_created: 2018-12-11T11:49:20Z
date_published: 2017-05-03T00:00:00Z
date_updated: 2023-09-26T15:37:02Z
day: '03'
department:
- _id: SiHi
- _id: MaJö
doi: 10.1016/j.neuron.2017.04.012
ec_funded: 1
external_id:
isi:
- '000400466700011'
intvolume: ' 94'
isi: 1
issue: '3'
language:
- iso: eng
month: '05'
oa_version: None
page: 517 - 533.e3
project:
- _id: 25D61E48-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '618444'
name: Molecular Mechanisms of Cerebral Cortex Development
- _id: 25D7962E-B435-11E9-9278-68D0E5697425
grant_number: RGP0053/2014
name: Quantitative Structure-Function Analysis of Cerebral Cortex Assembly at Clonal
Level
publication: Neuron
publication_identifier:
issn:
- '08966273'
publication_status: published
publisher: Cell Press
publist_id: '6473'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Mosaic analysis with double markers reveals distinct sequential functions of
Lgl1 in neural stem cells
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 94
year: '2017'
...