---
_id: '6013'
abstract:
- lang: eng
  text: The first hundred attoseconds of the electron dynamics during strong field
    tunneling ionization are investigated. We quantify theoretically how the electron’s
    classical trajectories in the continuum emerge from the tunneling process and
    test the results with those achieved in parallel from attoclock measurements.
    An especially high sensitivity on the tunneling barrier is accomplished here by
    comparing the momentum distributions of two atomic species of slightly deviating
    atomic potentials (argon and krypton) being ionized under absolutely identical
    conditions with near-infrared laser pulses (1300 nm). The agreement between experiment
    and theory provides clear evidence for a nonzero tunneling time delay and a nonvanishing
    longitudinal momentum of the electron at the “tunnel exit.”
article_number: '023201'
arxiv: 1
author:
- first_name: Nicolas
  full_name: Camus, Nicolas
  last_name: Camus
- first_name: Enderalp
  full_name: Yakaboylu, Enderalp
  id: 38CB71F6-F248-11E8-B48F-1D18A9856A87
  last_name: Yakaboylu
  orcid: 0000-0001-5973-0874
- first_name: Lutz
  full_name: Fechner, Lutz
  last_name: Fechner
- first_name: Michael
  full_name: Klaiber, Michael
  last_name: Klaiber
- first_name: Martin
  full_name: Laux, Martin
  last_name: Laux
- first_name: Yonghao
  full_name: Mi, Yonghao
  last_name: Mi
- first_name: Karen Z.
  full_name: Hatsagortsyan, Karen Z.
  last_name: Hatsagortsyan
- first_name: Thomas
  full_name: Pfeifer, Thomas
  last_name: Pfeifer
- first_name: Christoph H.
  full_name: Keitel, Christoph H.
  last_name: Keitel
- first_name: Robert
  full_name: Moshammer, Robert
  last_name: Moshammer
citation:
  ama: Camus N, Yakaboylu E, Fechner L, et al. Experimental evidence for quantum tunneling
    time. <i>Physical Review Letters</i>. 2017;119(2). doi:<a href="https://doi.org/10.1103/PhysRevLett.119.023201">10.1103/PhysRevLett.119.023201</a>
  apa: Camus, N., Yakaboylu, E., Fechner, L., Klaiber, M., Laux, M., Mi, Y., … Moshammer,
    R. (2017). Experimental evidence for quantum tunneling time. <i>Physical Review
    Letters</i>. American Physical Society. <a href="https://doi.org/10.1103/PhysRevLett.119.023201">https://doi.org/10.1103/PhysRevLett.119.023201</a>
  chicago: Camus, Nicolas, Enderalp Yakaboylu, Lutz Fechner, Michael Klaiber, Martin
    Laux, Yonghao Mi, Karen Z. Hatsagortsyan, Thomas Pfeifer, Christoph H. Keitel,
    and Robert Moshammer. “Experimental Evidence for Quantum Tunneling Time.” <i>Physical
    Review Letters</i>. American Physical Society, 2017. <a href="https://doi.org/10.1103/PhysRevLett.119.023201">https://doi.org/10.1103/PhysRevLett.119.023201</a>.
  ieee: N. Camus <i>et al.</i>, “Experimental evidence for quantum tunneling time,”
    <i>Physical Review Letters</i>, vol. 119, no. 2. American Physical Society, 2017.
  ista: Camus N, Yakaboylu E, Fechner L, Klaiber M, Laux M, Mi Y, Hatsagortsyan KZ,
    Pfeifer T, Keitel CH, Moshammer R. 2017. Experimental evidence for quantum tunneling
    time. Physical Review Letters. 119(2), 023201.
  mla: Camus, Nicolas, et al. “Experimental Evidence for Quantum Tunneling Time.”
    <i>Physical Review Letters</i>, vol. 119, no. 2, 023201, American Physical Society,
    2017, doi:<a href="https://doi.org/10.1103/PhysRevLett.119.023201">10.1103/PhysRevLett.119.023201</a>.
  short: N. Camus, E. Yakaboylu, L. Fechner, M. Klaiber, M. Laux, Y. Mi, K.Z. Hatsagortsyan,
    T. Pfeifer, C.H. Keitel, R. Moshammer, Physical Review Letters 119 (2017).
date_created: 2019-02-14T15:24:13Z
date_published: 2017-07-14T00:00:00Z
date_updated: 2023-02-23T11:13:36Z
day: '14'
department:
- _id: MiLe
doi: 10.1103/PhysRevLett.119.023201
external_id:
  arxiv:
  - '1611.03701'
intvolume: '       119'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1611.03701
month: '07'
oa: 1
oa_version: Preprint
publication: Physical Review Letters
publication_identifier:
  eissn:
  - 1079-7114
  issn:
  - 0031-9007
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
related_material:
  record:
  - id: '313'
    relation: earlier_version
    status: public
scopus_import: 1
status: public
title: Experimental evidence for quantum tunneling time
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 119
year: '2017'
...
---
_id: '603'
abstract:
- lang: eng
  text: During transcription, RNA polymerase II (Pol II) associates with the conserved
    elongation factor DSIF. DSIF renders the elongation complex stable and functions
    during Pol II pausing and RNA processing. We combined cryo-EM and X-ray crystallography
    to determine the structure of the mammalian Pol II-DSIF elongation complex at
    a nominal resolution of 3.4. Human DSIF has a modular structure with two domains
    forming a DNA clamp, two domains forming an RNA clamp, and one domain buttressing
    the RNA clamp. The clamps maintain the transcription bubble, position upstream
    DNA, and retain the RNA transcript in the exit tunnel. The mobile C-terminal region
    of DSIF is located near exiting RNA, where it can recruit factors for RNA processing.
    The structure provides insight into the roles of DSIF during mRNA synthesis.
article_processing_charge: No
author:
- first_name: Carrie A
  full_name: Bernecky, Carrie A
  id: 2CB9DFE2-F248-11E8-B48F-1D18A9856A87
  last_name: Bernecky
  orcid: 0000-0003-0893-7036
- first_name: Jürgen
  full_name: Plitzko, Jürgen
  last_name: Plitzko
- first_name: Patrick
  full_name: Cramer, Patrick
  last_name: Cramer
citation:
  ama: Bernecky C, Plitzko J, Cramer P. Structure of a transcribing RNA polymerase
    II-DSIF complex reveals a multidentate DNA-RNA clamp. <i>Nature Structural and
    Molecular Biology</i>. 2017;24(10):809-815. doi:<a href="https://doi.org/10.1038/nsmb.3465">10.1038/nsmb.3465</a>
  apa: Bernecky, C., Plitzko, J., &#38; Cramer, P. (2017). Structure of a transcribing
    RNA polymerase II-DSIF complex reveals a multidentate DNA-RNA clamp. <i>Nature
    Structural and Molecular Biology</i>. Nature Publishing Group. <a href="https://doi.org/10.1038/nsmb.3465">https://doi.org/10.1038/nsmb.3465</a>
  chicago: Bernecky, Carrie, Jürgen Plitzko, and Patrick Cramer. “Structure of a Transcribing
    RNA Polymerase II-DSIF Complex Reveals a Multidentate DNA-RNA Clamp.” <i>Nature
    Structural and Molecular Biology</i>. Nature Publishing Group, 2017. <a href="https://doi.org/10.1038/nsmb.3465">https://doi.org/10.1038/nsmb.3465</a>.
  ieee: C. Bernecky, J. Plitzko, and P. Cramer, “Structure of a transcribing RNA polymerase
    II-DSIF complex reveals a multidentate DNA-RNA clamp,” <i>Nature Structural and
    Molecular Biology</i>, vol. 24, no. 10. Nature Publishing Group, pp. 809–815,
    2017.
  ista: Bernecky C, Plitzko J, Cramer P. 2017. Structure of a transcribing RNA polymerase
    II-DSIF complex reveals a multidentate DNA-RNA clamp. Nature Structural and Molecular
    Biology. 24(10), 809–815.
  mla: Bernecky, Carrie, et al. “Structure of a Transcribing RNA Polymerase II-DSIF
    Complex Reveals a Multidentate DNA-RNA Clamp.” <i>Nature Structural and Molecular
    Biology</i>, vol. 24, no. 10, Nature Publishing Group, 2017, pp. 809–15, doi:<a
    href="https://doi.org/10.1038/nsmb.3465">10.1038/nsmb.3465</a>.
  short: C. Bernecky, J. Plitzko, P. Cramer, Nature Structural and Molecular Biology
    24 (2017) 809–815.
date_created: 2018-12-11T11:47:26Z
date_published: 2017-10-05T00:00:00Z
date_updated: 2021-01-12T08:05:47Z
day: '05'
doi: 10.1038/nsmb.3465
extern: '1'
intvolume: '        24'
issue: '10'
language:
- iso: eng
month: '10'
oa_version: None
page: 809 - 815
publication: Nature Structural and Molecular Biology
publication_identifier:
  issn:
  - '15459993'
publication_status: published
publisher: Nature Publishing Group
publist_id: '7202'
quality_controlled: '1'
status: public
title: Structure of a transcribing RNA polymerase II-DSIF complex reveals a multidentate
  DNA-RNA clamp
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 24
year: '2017'
...
---
_id: '604'
abstract:
- lang: eng
  text: In several settings of physics and chemistry one has to deal with molecules
    interacting with some kind of an external environment, be it a gas, a solution,
    or a crystal surface. Understanding molecular processes in the presence of such
    a many-particle bath is inherently challenging, and usually requires large-scale
    numerical computations. Here, we present an alternative approach to the problem,
    based on the notion of the angulon quasiparticle. We show that molecules rotating
    inside superfluid helium nanodroplets and Bose–Einstein condensates form angulons,
    and therefore can be described by straightforward solutions of a simple microscopic
    Hamiltonian. Casting the problem in the language of angulons allows us not only
    to greatly simplify it, but also to gain insights into the origins of the observed
    phenomena and to make predictions for future experimental studies.
alternative_title:
- Theoretical and Computational Chemistry Series
author:
- first_name: Mikhail
  full_name: Lemeshko, Mikhail
  id: 37CB05FA-F248-11E8-B48F-1D18A9856A87
  last_name: Lemeshko
  orcid: 0000-0002-6990-7802
- first_name: Richard
  full_name: Schmidt, Richard
  last_name: Schmidt
citation:
  ama: 'Lemeshko M, Schmidt R. Molecular impurities interacting with a many-particle
    environment: From ultracold gases to helium nanodroplets. In: Dulieu O, Osterwalder
    A, eds. <i>Cold Chemistry: Molecular Scattering and Reactivity Near Absolute Zero
    </i>. Vol 11. Theoretical and Computational Chemistry Series. The Royal Society
    of Chemistry; 2017:444-495. doi:<a href="https://doi.org/10.1039/9781782626800-00444">10.1039/9781782626800-00444</a>'
  apa: 'Lemeshko, M., &#38; Schmidt, R. (2017). Molecular impurities interacting with
    a many-particle environment: From ultracold gases to helium nanodroplets. In O.
    Dulieu &#38; A. Osterwalder (Eds.), <i>Cold Chemistry: Molecular Scattering and
    Reactivity Near Absolute Zero </i> (Vol. 11, pp. 444–495). The Royal Society of
    Chemistry. <a href="https://doi.org/10.1039/9781782626800-00444">https://doi.org/10.1039/9781782626800-00444</a>'
  chicago: 'Lemeshko, Mikhail, and Richard Schmidt. “Molecular Impurities Interacting
    with a Many-Particle Environment: From Ultracold Gases to Helium Nanodroplets.”
    In <i>Cold Chemistry: Molecular Scattering and Reactivity Near Absolute Zero </i>,
    edited by Oliver Dulieu and Andreas Osterwalder, 11:444–95. Theoretical and Computational
    Chemistry Series. The Royal Society of Chemistry, 2017. <a href="https://doi.org/10.1039/9781782626800-00444">https://doi.org/10.1039/9781782626800-00444</a>.'
  ieee: 'M. Lemeshko and R. Schmidt, “Molecular impurities interacting with a many-particle
    environment: From ultracold gases to helium nanodroplets,” in <i>Cold Chemistry:
    Molecular Scattering and Reactivity Near Absolute Zero </i>, vol. 11, O. Dulieu
    and A. Osterwalder, Eds. The Royal Society of Chemistry, 2017, pp. 444–495.'
  ista: 'Lemeshko M, Schmidt R. 2017.Molecular impurities interacting with a many-particle
    environment: From ultracold gases to helium nanodroplets. In: Cold Chemistry:
    Molecular Scattering and Reactivity Near Absolute Zero . Theoretical and Computational
    Chemistry Series, vol. 11, 444–495.'
  mla: 'Lemeshko, Mikhail, and Richard Schmidt. “Molecular Impurities Interacting
    with a Many-Particle Environment: From Ultracold Gases to Helium Nanodroplets.”
    <i>Cold Chemistry: Molecular Scattering and Reactivity Near Absolute Zero </i>,
    edited by Oliver Dulieu and Andreas Osterwalder, vol. 11, The Royal Society of
    Chemistry, 2017, pp. 444–95, doi:<a href="https://doi.org/10.1039/9781782626800-00444">10.1039/9781782626800-00444</a>.'
  short: 'M. Lemeshko, R. Schmidt, in:, O. Dulieu, A. Osterwalder (Eds.), Cold Chemistry:
    Molecular Scattering and Reactivity Near Absolute Zero , The Royal Society of
    Chemistry, 2017, pp. 444–495.'
date_created: 2018-12-11T11:47:27Z
date_published: 2017-12-14T00:00:00Z
date_updated: 2021-01-12T08:05:50Z
day: '14'
department:
- _id: MiLe
doi: 10.1039/9781782626800-00444
editor:
- first_name: Oliver
  full_name: Dulieu, Oliver
  last_name: Dulieu
- first_name: Andreas
  full_name: Osterwalder, Andreas
  last_name: Osterwalder
intvolume: '        11'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1703.06753
month: '12'
oa: 1
oa_version: Submitted Version
page: 444 - 495
publication: 'Cold Chemistry: Molecular Scattering and Reactivity Near Absolute Zero '
publication_identifier:
  issn:
  - '20413181'
publication_status: published
publisher: The Royal Society of Chemistry
publist_id: '7201'
quality_controlled: '1'
scopus_import: 1
series_title: Theoretical and Computational Chemistry Series
status: public
title: 'Molecular impurities interacting with a many-particle environment: From ultracold
  gases to helium nanodroplets'
type: book_chapter
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 11
year: '2017'
...
---
_id: '605'
abstract:
- lang: eng
  text: 'Position based cryptography (PBC), proposed in the seminal work of Chandran,
    Goyal, Moriarty, and Ostrovsky (SIAM J. Computing, 2014), aims at constructing
    cryptographic schemes in which the identity of the user is his geographic position.
    Chandran et al. construct PBC schemes for secure positioning and position-based
    key agreement in the bounded-storage model (Maurer, J. Cryptology, 1992). Apart
    from bounded memory, their security proofs need a strong additional restriction
    on the power of the adversary: he cannot compute joint functions of his inputs.
    Removing this assumption is left as an open problem. We show that an answer to
    this question would resolve a long standing open problem in multiparty communication
    complexity: finding a function that is hard to compute with low communication
    complexity in the simultaneous message model, but easy to compute in the fully
    adaptive model. On a more positive side: we also show some implications in the
    other direction, i.e.: we prove that lower bounds on the communication complexity
    of certain multiparty problems imply existence of PBC primitives. Using this result
    we then show two attractive ways to “bypass” our hardness result: the first uses
    the random oracle model, the second weakens the locality requirement in the bounded-storage
    model to online computability. The random oracle construction is arguably one
    of the simplest proposed so far in this area. Our results indicate that constructing
    improved provably secure protocols for PBC requires a better understanding of
    multiparty communication complexity. This is yet another example where negative
    results in one area (in our case: lower bounds in multiparty communication complexity)
    can be used to construct secure cryptographic schemes.'
alternative_title:
- LNCS
author:
- first_name: Joshua
  full_name: Brody, Joshua
  last_name: Brody
- first_name: Stefan
  full_name: Dziembowski, Stefan
  last_name: Dziembowski
- first_name: Sebastian
  full_name: Faust, Sebastian
  last_name: Faust
- first_name: Krzysztof Z
  full_name: Pietrzak, Krzysztof Z
  id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
  last_name: Pietrzak
  orcid: 0000-0002-9139-1654
citation:
  ama: 'Brody J, Dziembowski S, Faust S, Pietrzak KZ. Position based cryptography
    and multiparty communication complexity. In: Kalai Y, Reyzin L, eds. Vol 10677.
    Springer; 2017:56-81. doi:<a href="https://doi.org/10.1007/978-3-319-70500-2_3">10.1007/978-3-319-70500-2_3</a>'
  apa: 'Brody, J., Dziembowski, S., Faust, S., &#38; Pietrzak, K. Z. (2017). Position
    based cryptography and multiparty communication complexity. In Y. Kalai &#38;
    L. Reyzin (Eds.) (Vol. 10677, pp. 56–81). Presented at the TCC: Theory of Cryptography
    Conference, Baltimore, MD, United States: Springer. <a href="https://doi.org/10.1007/978-3-319-70500-2_3">https://doi.org/10.1007/978-3-319-70500-2_3</a>'
  chicago: Brody, Joshua, Stefan Dziembowski, Sebastian Faust, and Krzysztof Z Pietrzak.
    “Position Based Cryptography and Multiparty Communication Complexity.” edited
    by Yael Kalai and Leonid Reyzin, 10677:56–81. Springer, 2017. <a href="https://doi.org/10.1007/978-3-319-70500-2_3">https://doi.org/10.1007/978-3-319-70500-2_3</a>.
  ieee: 'J. Brody, S. Dziembowski, S. Faust, and K. Z. Pietrzak, “Position based cryptography
    and multiparty communication complexity,” presented at the TCC: Theory of Cryptography
    Conference, Baltimore, MD, United States, 2017, vol. 10677, pp. 56–81.'
  ista: 'Brody J, Dziembowski S, Faust S, Pietrzak KZ. 2017. Position based cryptography
    and multiparty communication complexity. TCC: Theory of Cryptography Conference,
    LNCS, vol. 10677, 56–81.'
  mla: Brody, Joshua, et al. <i>Position Based Cryptography and Multiparty Communication
    Complexity</i>. Edited by Yael Kalai and Leonid Reyzin, vol. 10677, Springer,
    2017, pp. 56–81, doi:<a href="https://doi.org/10.1007/978-3-319-70500-2_3">10.1007/978-3-319-70500-2_3</a>.
  short: J. Brody, S. Dziembowski, S. Faust, K.Z. Pietrzak, in:, Y. Kalai, L. Reyzin
    (Eds.), Springer, 2017, pp. 56–81.
conference:
  end_date: 2017-11-15
  location: Baltimore, MD, United States
  name: 'TCC: Theory of Cryptography Conference'
  start_date: 2017-11-12
date_created: 2018-12-11T11:47:27Z
date_published: 2017-11-05T00:00:00Z
date_updated: 2021-01-12T08:05:53Z
day: '05'
department:
- _id: KrPi
doi: 10.1007/978-3-319-70500-2_3
ec_funded: 1
editor:
- first_name: Yael
  full_name: Kalai, Yael
  last_name: Kalai
- first_name: Leonid
  full_name: Reyzin, Leonid
  last_name: Reyzin
intvolume: '     10677'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://eprint.iacr.org/2016/536
month: '11'
oa: 1
oa_version: Submitted Version
page: 56 - 81
project:
- _id: 258AA5B2-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '682815'
  name: Teaching Old Crypto New Tricks
publication_identifier:
  isbn:
  - 978-331970499-9
publication_status: published
publisher: Springer
publist_id: '7200'
quality_controlled: '1'
scopus_import: 1
status: public
title: Position based cryptography and multiparty communication complexity
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 10677
year: '2017'
...
---
_id: '6059'
abstract:
- lang: eng
  text: Neutrophils or polymorphonuclear cells (PMN) eliminate bacteria via phagocytosis
    and/or NETosis. Apartfrom these conventional roles, PMN also have immune-regulatory
    functions. They can transdifferentiateand upregulate MHCII as well as ligands
    for costimulatory receptors which enables them to behave asantigen presenting
    cells (APC). The initial step for activating T-cells is the formation of an immunesynapse
    between T-cells and antigen-presenting cells. However, the immune synapse that
    develops atthe PMN/T-cell contact zone is as yet hardly investigated due to the
    non-availability of methods foranalysis of large number of PMN interactions. In
    order to overcome these obstacles, we introduce herea workflow to analyse the
    immune synapse of primary human PMN and T-cells using multispectral imag-ing flow
    cytometry (InFlow microscopy) and super-resolution microscopy. For that purpose,
    we used CD3and CD66b as the lineage markers for T-cells and PMN, respectively.
    Thereafter, we applied and criticallydiscussed various ‘‘masks” for identification
    of T-cell PMN interactions. Using this approach, we foundthat a small fraction
    of transdifferentiated PMN (CD66b+CD86high) formed stable PMN/T-cell conjugates.Interestingly,
    while both CD3 and CD66b accumulation in the immune synapse was dependent on thematuration
    state of the PMN, only CD3 accumulation was greatly enhanced by the presence of
    superanti-gen. The actin cytoskeleton was weakly rearranged at the PMN side on
    the immune synapse upon contactwith a T-cell in the presence of superantigen.
    A more detailed analysis using super-resolution microscopy(structured-illumination
    microscopy, SIM) confirmed this finding. Together, we present an InFlow micro-scopy
    based approach for the large scale analysis of PMN/T-cell interactions and – combined
    with SIM – apossibility for an in-depth analysis of protein translocation at the
    site of interactions.
author:
- first_name: Emre
  full_name: Balta, Emre
  last_name: Balta
- first_name: Julian A
  full_name: Stopp, Julian A
  id: 489E3F00-F248-11E8-B48F-1D18A9856A87
  last_name: Stopp
- first_name: Laura
  full_name: Castelletti, Laura
  last_name: Castelletti
- first_name: Henning
  full_name: Kirchgessner, Henning
  last_name: Kirchgessner
- first_name: Yvonne
  full_name: Samstag, Yvonne
  last_name: Samstag
- first_name: Guido H.
  full_name: Wabnitz, Guido H.
  last_name: Wabnitz
citation:
  ama: Balta E, Stopp JA, Castelletti L, Kirchgessner H, Samstag Y, Wabnitz GH. Qualitative
    and quantitative analysis of PMN/T-cell interactions by InFlow and super-resolution
    microscopy. <i>Methods</i>. 2017;112(1):25-38. doi:<a href="https://doi.org/10.1016/j.ymeth.2016.09.013">10.1016/j.ymeth.2016.09.013</a>
  apa: Balta, E., Stopp, J. A., Castelletti, L., Kirchgessner, H., Samstag, Y., &#38;
    Wabnitz, G. H. (2017). Qualitative and quantitative analysis of PMN/T-cell interactions
    by InFlow and super-resolution microscopy. <i>Methods</i>. Elsevier. <a href="https://doi.org/10.1016/j.ymeth.2016.09.013">https://doi.org/10.1016/j.ymeth.2016.09.013</a>
  chicago: Balta, Emre, Julian A Stopp, Laura Castelletti, Henning Kirchgessner, Yvonne
    Samstag, and Guido H. Wabnitz. “Qualitative and Quantitative Analysis of PMN/T-Cell
    Interactions by InFlow and Super-Resolution Microscopy.” <i>Methods</i>. Elsevier,
    2017. <a href="https://doi.org/10.1016/j.ymeth.2016.09.013">https://doi.org/10.1016/j.ymeth.2016.09.013</a>.
  ieee: E. Balta, J. A. Stopp, L. Castelletti, H. Kirchgessner, Y. Samstag, and G.
    H. Wabnitz, “Qualitative and quantitative analysis of PMN/T-cell interactions
    by InFlow and super-resolution microscopy,” <i>Methods</i>, vol. 112, no. 1. Elsevier,
    pp. 25–38, 2017.
  ista: Balta E, Stopp JA, Castelletti L, Kirchgessner H, Samstag Y, Wabnitz GH. 2017.
    Qualitative and quantitative analysis of PMN/T-cell interactions by InFlow and
    super-resolution microscopy. Methods. 112(1), 25–38.
  mla: Balta, Emre, et al. “Qualitative and Quantitative Analysis of PMN/T-Cell Interactions
    by InFlow and Super-Resolution Microscopy.” <i>Methods</i>, vol. 112, no. 1, Elsevier,
    2017, pp. 25–38, doi:<a href="https://doi.org/10.1016/j.ymeth.2016.09.013">10.1016/j.ymeth.2016.09.013</a>.
  short: E. Balta, J.A. Stopp, L. Castelletti, H. Kirchgessner, Y. Samstag, G.H. Wabnitz,
    Methods 112 (2017) 25–38.
date_created: 2019-02-26T13:45:17Z
date_published: 2017-01-01T00:00:00Z
date_updated: 2021-01-12T08:05:57Z
day: '01'
doi: 10.1016/j.ymeth.2016.09.013
extern: '1'
external_id:
  pmid:
  - '27693880'
intvolume: '       112'
issue: '1'
language:
- iso: eng
month: '01'
oa_version: None
page: 25-38
pmid: 1
publication: Methods
publication_identifier:
  issn:
  - 1046-2023
publication_status: published
publisher: Elsevier
quality_controlled: '1'
related_material:
  link:
  - relation: supplementary_material
    url: http://dx.doi.org/10.1016/j.ymeth.2016.09.013
status: public
title: Qualitative and quantitative analysis of PMN/T-cell interactions by InFlow
  and super-resolution microscopy
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 112
year: '2017'
...
---
_id: '609'
abstract:
- lang: eng
  text: Several cryptographic schemes and applications are based on functions that
    are both reasonably efficient to compute and moderately hard to invert, including
    client puzzles for Denial-of-Service protection, password protection via salted
    hashes, or recent proof-of-work blockchain systems. Despite their wide use, a
    definition of this concept has not yet been distilled and formalized explicitly.
    Instead, either the applications are proven directly based on the assumptions
    underlying the function, or some property of the function is proven, but the security
    of the application is argued only informally. The goal of this work is to provide
    a (universal) definition that decouples the efforts of designing new moderately
    hard functions and of building protocols based on them, serving as an interface
    between the two. On a technical level, beyond the mentioned definitions, we instantiate
    the model for four different notions of hardness. We extend the work of Alwen
    and Serbinenko (STOC 2015) by providing a general tool for proving security for
    the first notion of memory-hard functions that allows for provably secure applications.
    The tool allows us to recover all of the graph-theoretic techniques developed
    for proving security under the older, non-composable, notion of security used
    by Alwen and Serbinenko. As an application of our definition of moderately hard
    functions, we prove the security of two different schemes for proofs of effort
    (PoE). We also formalize and instantiate the concept of a non-interactive proof
    of effort (niPoE), in which the proof is not bound to a particular communication
    context but rather any bit-string chosen by the prover.
alternative_title:
- LNCS
author:
- first_name: Joel F
  full_name: Alwen, Joel F
  id: 2A8DFA8C-F248-11E8-B48F-1D18A9856A87
  last_name: Alwen
- first_name: Björn
  full_name: Tackmann, Björn
  last_name: Tackmann
citation:
  ama: 'Alwen JF, Tackmann B. Moderately hard functions: Definition, instantiations,
    and applications. In: Kalai Y, Reyzin L, eds. Vol 10677. Springer; 2017:493-526.
    doi:<a href="https://doi.org/10.1007/978-3-319-70500-2_17">10.1007/978-3-319-70500-2_17</a>'
  apa: 'Alwen, J. F., &#38; Tackmann, B. (2017). Moderately hard functions: Definition,
    instantiations, and applications. In Y. Kalai &#38; L. Reyzin (Eds.) (Vol. 10677,
    pp. 493–526). Presented at the TCC: Theory of Cryptography, Baltimore, MD, United
    States: Springer. <a href="https://doi.org/10.1007/978-3-319-70500-2_17">https://doi.org/10.1007/978-3-319-70500-2_17</a>'
  chicago: 'Alwen, Joel F, and Björn Tackmann. “Moderately Hard Functions: Definition,
    Instantiations, and Applications.” edited by Yael Kalai and Leonid Reyzin, 10677:493–526.
    Springer, 2017. <a href="https://doi.org/10.1007/978-3-319-70500-2_17">https://doi.org/10.1007/978-3-319-70500-2_17</a>.'
  ieee: 'J. F. Alwen and B. Tackmann, “Moderately hard functions: Definition, instantiations,
    and applications,” presented at the TCC: Theory of Cryptography, Baltimore, MD,
    United States, 2017, vol. 10677, pp. 493–526.'
  ista: 'Alwen JF, Tackmann B. 2017. Moderately hard functions: Definition, instantiations,
    and applications. TCC: Theory of Cryptography, LNCS, vol. 10677, 493–526.'
  mla: 'Alwen, Joel F., and Björn Tackmann. <i>Moderately Hard Functions: Definition,
    Instantiations, and Applications</i>. Edited by Yael Kalai and Leonid Reyzin,
    vol. 10677, Springer, 2017, pp. 493–526, doi:<a href="https://doi.org/10.1007/978-3-319-70500-2_17">10.1007/978-3-319-70500-2_17</a>.'
  short: J.F. Alwen, B. Tackmann, in:, Y. Kalai, L. Reyzin (Eds.), Springer, 2017,
    pp. 493–526.
conference:
  end_date: 2017-11-15
  location: Baltimore, MD, United States
  name: 'TCC: Theory of Cryptography'
  start_date: 2017-11-12
date_created: 2018-12-11T11:47:28Z
date_published: 2017-11-05T00:00:00Z
date_updated: 2021-01-12T08:06:04Z
day: '05'
department:
- _id: KrPi
doi: 10.1007/978-3-319-70500-2_17
editor:
- first_name: Yael
  full_name: Kalai, Yael
  last_name: Kalai
- first_name: Leonid
  full_name: Reyzin, Leonid
  last_name: Reyzin
intvolume: '     10677'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://eprint.iacr.org/2017/945
month: '11'
oa: 1
oa_version: Submitted Version
page: 493 - 526
publication_identifier:
  isbn:
  - 978-331970499-9
publication_status: published
publisher: Springer
publist_id: '7196'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'Moderately hard functions: Definition, instantiations, and applications'
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 10677
year: '2017'
...
---
_id: '610'
abstract:
- lang: eng
  text: 'The fact that the complete graph K5 does not embed in the plane has been
    generalized in two independent directions. On the one hand, the solution of the
    classical Heawood problem for graphs on surfaces established that the complete
    graph Kn embeds in a closed surface M (other than the Klein bottle) if and only
    if (n−3)(n−4) ≤ 6b1(M), where b1(M) is the first Z2-Betti number of M. On the
    other hand, van Kampen and Flores proved that the k-skeleton of the n-dimensional
    simplex (the higher-dimensional analogue of Kn+1) embeds in R2k if and only if
    n ≤ 2k + 1. Two decades ago, Kühnel conjectured that the k-skeleton of the n-simplex
    embeds in a compact, (k − 1)-connected 2k-manifold with kth Z2-Betti number bk
    only if the following generalized Heawood inequality holds: (k+1 n−k−1) ≤ (k+1
    2k+1)bk. This is a common generalization of the case of graphs on surfaces as
    well as the van Kampen–Flores theorem. In the spirit of Kühnel’s conjecture, we
    prove that if the k-skeleton of the n-simplex embeds in a compact 2k-manifold
    with kth Z2-Betti number bk, then n ≤ 2bk(k 2k+2)+2k+4. This bound is weaker than
    the generalized Heawood inequality, but does not require the assumption that M
    is (k−1)-connected. Our results generalize to maps without q-covered points, in
    the spirit of Tverberg’s theorem, for q a prime power. Our proof uses a result
    of Volovikov about maps that satisfy a certain homological triviality condition.'
acknowledgement: The work by Z. P. was partially supported by the Israel Science Foundation
  grant ISF-768/12. The work by Z. P. and M. T. was partially supported by the project
  CE-ITI (GACR P202/12/G061) of the Czech Science Foundation and by the ERC Advanced
  Grant No. 267165. Part of the research work of M.T. was conducted at IST Austria,
  supported by an IST Fellowship. The research of P. P. was supported by the ERC Advanced
  grant no. 320924. The work by I. M. and U. W. was supported by the Swiss National
  Science Foundation (grants SNSF-200020-138230 and SNSF-PP00P2-138948). The collaboration
  between U. W. and X. G. was partially supported by the LabEx Bézout (ANR-10-LABX-58).
author:
- first_name: Xavier
  full_name: Goaoc, Xavier
  last_name: Goaoc
- first_name: Isaac
  full_name: Mabillard, Isaac
  id: 32BF9DAA-F248-11E8-B48F-1D18A9856A87
  last_name: Mabillard
- first_name: Pavel
  full_name: Paták, Pavel
  last_name: Paták
- first_name: Zuzana
  full_name: Patakova, Zuzana
  id: 48B57058-F248-11E8-B48F-1D18A9856A87
  last_name: Patakova
  orcid: 0000-0002-3975-1683
- first_name: Martin
  full_name: Tancer, Martin
  id: 38AC689C-F248-11E8-B48F-1D18A9856A87
  last_name: Tancer
  orcid: 0000-0002-1191-6714
- first_name: Uli
  full_name: Wagner, Uli
  id: 36690CA2-F248-11E8-B48F-1D18A9856A87
  last_name: Wagner
  orcid: 0000-0002-1494-0568
citation:
  ama: 'Goaoc X, Mabillard I, Paták P, Patakova Z, Tancer M, Wagner U. On generalized
    Heawood inequalities for manifolds: A van Kampen–Flores type nonembeddability
    result. <i>Israel Journal of Mathematics</i>. 2017;222(2):841-866. doi:<a href="https://doi.org/10.1007/s11856-017-1607-7">10.1007/s11856-017-1607-7</a>'
  apa: 'Goaoc, X., Mabillard, I., Paták, P., Patakova, Z., Tancer, M., &#38; Wagner,
    U. (2017). On generalized Heawood inequalities for manifolds: A van Kampen–Flores
    type nonembeddability result. <i>Israel Journal of Mathematics</i>. Springer.
    <a href="https://doi.org/10.1007/s11856-017-1607-7">https://doi.org/10.1007/s11856-017-1607-7</a>'
  chicago: 'Goaoc, Xavier, Isaac Mabillard, Pavel Paták, Zuzana Patakova, Martin Tancer,
    and Uli Wagner. “On Generalized Heawood Inequalities for Manifolds: A van Kampen–Flores
    Type Nonembeddability Result.” <i>Israel Journal of Mathematics</i>. Springer,
    2017. <a href="https://doi.org/10.1007/s11856-017-1607-7">https://doi.org/10.1007/s11856-017-1607-7</a>.'
  ieee: 'X. Goaoc, I. Mabillard, P. Paták, Z. Patakova, M. Tancer, and U. Wagner,
    “On generalized Heawood inequalities for manifolds: A van Kampen–Flores type nonembeddability
    result,” <i>Israel Journal of Mathematics</i>, vol. 222, no. 2. Springer, pp.
    841–866, 2017.'
  ista: 'Goaoc X, Mabillard I, Paták P, Patakova Z, Tancer M, Wagner U. 2017. On generalized
    Heawood inequalities for manifolds: A van Kampen–Flores type nonembeddability
    result. Israel Journal of Mathematics. 222(2), 841–866.'
  mla: 'Goaoc, Xavier, et al. “On Generalized Heawood Inequalities for Manifolds:
    A van Kampen–Flores Type Nonembeddability Result.” <i>Israel Journal of Mathematics</i>,
    vol. 222, no. 2, Springer, 2017, pp. 841–66, doi:<a href="https://doi.org/10.1007/s11856-017-1607-7">10.1007/s11856-017-1607-7</a>.'
  short: X. Goaoc, I. Mabillard, P. Paták, Z. Patakova, M. Tancer, U. Wagner, Israel
    Journal of Mathematics 222 (2017) 841–866.
date_created: 2018-12-11T11:47:29Z
date_published: 2017-10-01T00:00:00Z
date_updated: 2023-02-23T10:02:13Z
day: '01'
department:
- _id: UlWa
doi: 10.1007/s11856-017-1607-7
ec_funded: 1
intvolume: '       222'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1610.09063
month: '10'
oa: 1
oa_version: Preprint
page: 841 - 866
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
publication: Israel Journal of Mathematics
publication_status: published
publisher: Springer
publist_id: '7194'
quality_controlled: '1'
related_material:
  record:
  - id: '1511'
    relation: earlier_version
    status: public
scopus_import: 1
status: public
title: 'On generalized Heawood inequalities for manifolds: A van Kampen–Flores type
  nonembeddability result'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 222
year: '2017'
...
---
_id: '611'
abstract:
- lang: eng
  text: Small RNAs (sRNAs) regulate genes in plants and animals. Here, we show that
    population-wide differences in color patterns in snapdragon flowers are caused
    by an inverted duplication that generates sRNAs. The complexity and size of the
    transcripts indicate that the duplication represents an intermediate on the pathway
    to microRNA evolution. The sRNAs repress a pigment biosynthesis gene, creating
    a yellow highlight at the site of pollinator entry. The inverted duplication exhibits
    steep clines in allele frequency in a natural hybrid zone, showing that the allele
    is under selection. Thus, regulatory interactions of evolutionarily recent sRNAs
    can be acted upon by selection and contribute to the evolution of phenotypic diversity.
author:
- first_name: Desmond
  full_name: Bradley, Desmond
  last_name: Bradley
- first_name: Ping
  full_name: Xu, Ping
  last_name: Xu
- first_name: Irina
  full_name: Mohorianu, Irina
  last_name: Mohorianu
- first_name: Annabel
  full_name: Whibley, Annabel
  last_name: Whibley
- first_name: David
  full_name: Field, David
  id: 419049E2-F248-11E8-B48F-1D18A9856A87
  last_name: Field
  orcid: 0000-0002-4014-8478
- first_name: Hugo
  full_name: Tavares, Hugo
  last_name: Tavares
- first_name: Matthew
  full_name: Couchman, Matthew
  last_name: Couchman
- first_name: Lucy
  full_name: Copsey, Lucy
  last_name: Copsey
- first_name: Rosemary
  full_name: Carpenter, Rosemary
  last_name: Carpenter
- first_name: Miaomiao
  full_name: Li, Miaomiao
  last_name: Li
- first_name: Qun
  full_name: Li, Qun
  last_name: Li
- first_name: Yongbiao
  full_name: Xue, Yongbiao
  last_name: Xue
- first_name: Tamas
  full_name: Dalmay, Tamas
  last_name: Dalmay
- first_name: Enrico
  full_name: Coen, Enrico
  last_name: Coen
citation:
  ama: Bradley D, Xu P, Mohorianu I, et al. Evolution of flower color pattern through
    selection on regulatory small RNAs. <i>Science</i>. 2017;358(6365):925-928. doi:<a
    href="https://doi.org/10.1126/science.aao3526">10.1126/science.aao3526</a>
  apa: Bradley, D., Xu, P., Mohorianu, I., Whibley, A., Field, D., Tavares, H., …
    Coen, E. (2017). Evolution of flower color pattern through selection on regulatory
    small RNAs. <i>Science</i>. American Association for the Advancement of Science.
    <a href="https://doi.org/10.1126/science.aao3526">https://doi.org/10.1126/science.aao3526</a>
  chicago: Bradley, Desmond, Ping Xu, Irina Mohorianu, Annabel Whibley, David Field,
    Hugo Tavares, Matthew Couchman, et al. “Evolution of Flower Color Pattern through
    Selection on Regulatory Small RNAs.” <i>Science</i>. American Association for
    the Advancement of Science, 2017. <a href="https://doi.org/10.1126/science.aao3526">https://doi.org/10.1126/science.aao3526</a>.
  ieee: D. Bradley <i>et al.</i>, “Evolution of flower color pattern through selection
    on regulatory small RNAs,” <i>Science</i>, vol. 358, no. 6365. American Association
    for the Advancement of Science, pp. 925–928, 2017.
  ista: Bradley D, Xu P, Mohorianu I, Whibley A, Field D, Tavares H, Couchman M, Copsey
    L, Carpenter R, Li M, Li Q, Xue Y, Dalmay T, Coen E. 2017. Evolution of flower
    color pattern through selection on regulatory small RNAs. Science. 358(6365),
    925–928.
  mla: Bradley, Desmond, et al. “Evolution of Flower Color Pattern through Selection
    on Regulatory Small RNAs.” <i>Science</i>, vol. 358, no. 6365, American Association
    for the Advancement of Science, 2017, pp. 925–28, doi:<a href="https://doi.org/10.1126/science.aao3526">10.1126/science.aao3526</a>.
  short: D. Bradley, P. Xu, I. Mohorianu, A. Whibley, D. Field, H. Tavares, M. Couchman,
    L. Copsey, R. Carpenter, M. Li, Q. Li, Y. Xue, T. Dalmay, E. Coen, Science 358
    (2017) 925–928.
date_created: 2018-12-11T11:47:29Z
date_published: 2017-11-17T00:00:00Z
date_updated: 2021-01-12T08:06:10Z
day: '17'
department:
- _id: NiBa
doi: 10.1126/science.aao3526
intvolume: '       358'
issue: '6365'
language:
- iso: eng
month: '11'
oa_version: None
page: 925 - 928
publication: Science
publication_identifier:
  issn:
  - '00368075'
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '7193'
quality_controlled: '1'
scopus_import: 1
status: public
title: Evolution of flower color pattern through selection on regulatory small RNAs
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 358
year: '2017'
...
---
_id: '6113'
author:
- first_name: Shigekazu
  full_name: Oda, Shigekazu
  last_name: Oda
- first_name: Yu
  full_name: Toyoshima, Yu
  last_name: Toyoshima
- first_name: Mario
  full_name: de Bono, Mario
  id: 4E3FF80E-F248-11E8-B48F-1D18A9856A87
  last_name: de Bono
  orcid: 0000-0001-8347-0443
citation:
  ama: Oda S, Toyoshima Y, de Bono M. Modulation of sensory information processing
    by a neuroglobin in Caenorhabditis elegans. <i>Proceedings of the National Academy
    of Sciences</i>. 2017;114(23):E4658-E4665. doi:<a href="https://doi.org/10.1073/pnas.1614596114">10.1073/pnas.1614596114</a>
  apa: Oda, S., Toyoshima, Y., &#38; de Bono, M. (2017). Modulation of sensory information
    processing by a neuroglobin in Caenorhabditis elegans. <i>Proceedings of the National
    Academy of Sciences</i>. National Academy of Sciences. <a href="https://doi.org/10.1073/pnas.1614596114">https://doi.org/10.1073/pnas.1614596114</a>
  chicago: Oda, Shigekazu, Yu Toyoshima, and Mario de Bono. “Modulation of Sensory
    Information Processing by a Neuroglobin in Caenorhabditis Elegans.” <i>Proceedings
    of the National Academy of Sciences</i>. National Academy of Sciences, 2017. <a
    href="https://doi.org/10.1073/pnas.1614596114">https://doi.org/10.1073/pnas.1614596114</a>.
  ieee: S. Oda, Y. Toyoshima, and M. de Bono, “Modulation of sensory information processing
    by a neuroglobin in Caenorhabditis elegans,” <i>Proceedings of the National Academy
    of Sciences</i>, vol. 114, no. 23. National Academy of Sciences, pp. E4658–E4665,
    2017.
  ista: Oda S, Toyoshima Y, de Bono M. 2017. Modulation of sensory information processing
    by a neuroglobin in Caenorhabditis elegans. Proceedings of the National Academy
    of Sciences. 114(23), E4658–E4665.
  mla: Oda, Shigekazu, et al. “Modulation of Sensory Information Processing by a Neuroglobin
    in Caenorhabditis Elegans.” <i>Proceedings of the National Academy of Sciences</i>,
    vol. 114, no. 23, National Academy of Sciences, 2017, pp. E4658–65, doi:<a href="https://doi.org/10.1073/pnas.1614596114">10.1073/pnas.1614596114</a>.
  short: S. Oda, Y. Toyoshima, M. de Bono, Proceedings of the National Academy of
    Sciences 114 (2017) E4658–E4665.
date_created: 2019-03-19T13:29:51Z
date_published: 2017-06-06T00:00:00Z
date_updated: 2021-01-12T08:06:11Z
day: '06'
ddc:
- '570'
doi: 10.1073/pnas.1614596114
extern: '1'
external_id:
  pmid:
  - '28536200'
file:
- access_level: open_access
  checksum: 9e42ce47090ecdad7d76f2dbdebb924e
  content_type: application/pdf
  creator: kschuh
  date_created: 2019-03-19T13:42:58Z
  date_updated: 2020-07-14T12:47:19Z
  file_id: '6114'
  file_name: 2017_PNAS_Oda.pdf
  file_size: 1469622
  relation: main_file
file_date_updated: 2020-07-14T12:47:19Z
has_accepted_license: '1'
intvolume: '       114'
issue: '23'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: E4658-E4665
pmid: 1
publication: Proceedings of the National Academy of Sciences
publication_identifier:
  issn:
  - 0027-8424
  - 1091-6490
publication_status: published
publisher: National Academy of Sciences
quality_controlled: '1'
status: public
title: Modulation of sensory information processing by a neuroglobin in Caenorhabditis
  elegans
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 114
year: '2017'
...
---
_id: '6115'
abstract:
- lang: eng
  text: Animals adjust their behavioral priorities according to momentary needs and
    prior experience. We show that Caenorhabditis elegans changes how it processes
    sensory information according to the oxygen environment it experienced recently.
    C. elegans acclimated to 7% O2 are aroused by CO2 and repelled by pheromones that
    attract animals acclimated to 21% O2. This behavioral plasticity arises from prolonged
    activity differences in a circuit that continuously signals O2 levels. A sustained
    change in the activity of O2-sensing neurons reprograms the properties of their
    postsynaptic partners, the RMG hub interneurons. RMG is gap-junctionally coupled
    to the ASK and ADL pheromone sensors that respectively drive pheromone attraction
    and repulsion. Prior O2 experience has opposite effects on the pheromone responsiveness
    of these neurons. These circuit changes provide a physiological correlate of altered
    pheromone valence. Our results suggest C. elegans stores a memory of recent O2
    experience in the RMG circuit and illustrate how a circuit is flexibly sculpted
    to guide behavioral decisions in a context-dependent manner.
author:
- first_name: Lorenz A.
  full_name: Fenk, Lorenz A.
  last_name: Fenk
- first_name: Mario
  full_name: de Bono, Mario
  id: 4E3FF80E-F248-11E8-B48F-1D18A9856A87
  last_name: de Bono
  orcid: 0000-0001-8347-0443
citation:
  ama: Fenk LA, de Bono M. Memory of recent oxygen experience switches pheromone valence
    inCaenorhabditis elegans. <i>Proceedings of the National Academy of Sciences</i>.
    2017;114(16):4195-4200. doi:<a href="https://doi.org/10.1073/pnas.1618934114">10.1073/pnas.1618934114</a>
  apa: Fenk, L. A., &#38; de Bono, M. (2017). Memory of recent oxygen experience switches
    pheromone valence inCaenorhabditis elegans. <i>Proceedings of the National Academy
    of Sciences</i>. National Academy of Sciences. <a href="https://doi.org/10.1073/pnas.1618934114">https://doi.org/10.1073/pnas.1618934114</a>
  chicago: Fenk, Lorenz A., and Mario de Bono. “Memory of Recent Oxygen Experience
    Switches Pheromone Valence InCaenorhabditis Elegans.” <i>Proceedings of the National
    Academy of Sciences</i>. National Academy of Sciences, 2017. <a href="https://doi.org/10.1073/pnas.1618934114">https://doi.org/10.1073/pnas.1618934114</a>.
  ieee: L. A. Fenk and M. de Bono, “Memory of recent oxygen experience switches pheromone
    valence inCaenorhabditis elegans,” <i>Proceedings of the National Academy of Sciences</i>,
    vol. 114, no. 16. National Academy of Sciences, pp. 4195–4200, 2017.
  ista: Fenk LA, de Bono M. 2017. Memory of recent oxygen experience switches pheromone
    valence inCaenorhabditis elegans. Proceedings of the National Academy of Sciences.
    114(16), 4195–4200.
  mla: Fenk, Lorenz A., and Mario de Bono. “Memory of Recent Oxygen Experience Switches
    Pheromone Valence InCaenorhabditis Elegans.” <i>Proceedings of the National Academy
    of Sciences</i>, vol. 114, no. 16, National Academy of Sciences, 2017, pp. 4195–200,
    doi:<a href="https://doi.org/10.1073/pnas.1618934114">10.1073/pnas.1618934114</a>.
  short: L.A. Fenk, M. de Bono, Proceedings of the National Academy of Sciences 114
    (2017) 4195–4200.
date_created: 2019-03-19T13:46:36Z
date_published: 2017-04-18T00:00:00Z
date_updated: 2021-01-12T08:06:11Z
day: '18'
ddc:
- '570'
doi: 10.1073/pnas.1618934114
extern: '1'
external_id:
  pmid:
  - '28373553'
file:
- access_level: open_access
  checksum: 1801bc8319b752fa17598004ec375279
  content_type: application/pdf
  creator: kschuh
  date_created: 2019-03-19T14:00:42Z
  date_updated: 2020-07-14T12:47:20Z
  file_id: '6116'
  file_name: 2017_PNAS_Fenk.pdf
  file_size: 1217696
  relation: main_file
file_date_updated: 2020-07-14T12:47:20Z
has_accepted_license: '1'
intvolume: '       114'
issue: '16'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 4195-4200
pmid: 1
publication: Proceedings of the National Academy of Sciences
publication_identifier:
  issn:
  - 0027-8424
  - 1091-6490
publication_status: published
publisher: National Academy of Sciences
quality_controlled: '1'
status: public
title: Memory of recent oxygen experience switches pheromone valence inCaenorhabditis
  elegans
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 114
year: '2017'
...
---
_id: '6117'
abstract:
- lang: eng
  text: 'Interleukin-17 (IL-17) is a major pro-inflammatory cytokine: it mediates
    responses to pathogens or tissue damage, and drives autoimmune diseases. Little
    is known about its role in the nervous system. Here we show that IL-17 has neuromodulator-like
    properties in Caenorhabditis elegans. IL-17 can act directly on neurons to alter
    their response properties and contribution to behaviour. Using unbiased genetic
    screens, we delineate an IL-17 signalling pathway and show that it acts in the
    RMG hub interneurons. Disrupting IL-17 signalling reduces RMG responsiveness to
    input from oxygen sensors, and renders sustained escape from 21% oxygen transient
    and contingent on additional stimuli. Over-activating IL-17 receptors abnormally
    heightens responses to 21% oxygen in RMG neurons and whole animals. IL-17 deficiency
    can be bypassed by optogenetic stimulation of RMG. Inducing IL-17 expression in
    adults can rescue mutant defects within 6 h. These findings reveal a non-immunological
    role of IL-17 modulating circuit function and behaviour.'
author:
- first_name: Changchun
  full_name: Chen, Changchun
  last_name: Chen
- first_name: Eisuke
  full_name: Itakura, Eisuke
  last_name: Itakura
- first_name: Geoffrey M.
  full_name: Nelson, Geoffrey M.
  last_name: Nelson
- first_name: Ming
  full_name: Sheng, Ming
  last_name: Sheng
- first_name: Patrick
  full_name: Laurent, Patrick
  last_name: Laurent
- first_name: Lorenz A.
  full_name: Fenk, Lorenz A.
  last_name: Fenk
- first_name: Rebecca A.
  full_name: Butcher, Rebecca A.
  last_name: Butcher
- first_name: Ramanujan S.
  full_name: Hegde, Ramanujan S.
  last_name: Hegde
- first_name: Mario
  full_name: de Bono, Mario
  id: 4E3FF80E-F248-11E8-B48F-1D18A9856A87
  last_name: de Bono
  orcid: 0000-0001-8347-0443
citation:
  ama: Chen C, Itakura E, Nelson GM, et al. IL-17 is a neuromodulator of Caenorhabditis
    elegans sensory responses. <i>Nature</i>. 2017;542(7639):43-48. doi:<a href="https://doi.org/10.1038/nature20818">10.1038/nature20818</a>
  apa: Chen, C., Itakura, E., Nelson, G. M., Sheng, M., Laurent, P., Fenk, L. A.,
    … de Bono, M. (2017). IL-17 is a neuromodulator of Caenorhabditis elegans sensory
    responses. <i>Nature</i>. Springer Nature. <a href="https://doi.org/10.1038/nature20818">https://doi.org/10.1038/nature20818</a>
  chicago: Chen, Changchun, Eisuke Itakura, Geoffrey M. Nelson, Ming Sheng, Patrick
    Laurent, Lorenz A. Fenk, Rebecca A. Butcher, Ramanujan S. Hegde, and Mario de
    Bono. “IL-17 Is a Neuromodulator of Caenorhabditis Elegans Sensory Responses.”
    <i>Nature</i>. Springer Nature, 2017. <a href="https://doi.org/10.1038/nature20818">https://doi.org/10.1038/nature20818</a>.
  ieee: C. Chen <i>et al.</i>, “IL-17 is a neuromodulator of Caenorhabditis elegans
    sensory responses,” <i>Nature</i>, vol. 542, no. 7639. Springer Nature, pp. 43–48,
    2017.
  ista: Chen C, Itakura E, Nelson GM, Sheng M, Laurent P, Fenk LA, Butcher RA, Hegde
    RS, de Bono M. 2017. IL-17 is a neuromodulator of Caenorhabditis elegans sensory
    responses. Nature. 542(7639), 43–48.
  mla: Chen, Changchun, et al. “IL-17 Is a Neuromodulator of Caenorhabditis Elegans
    Sensory Responses.” <i>Nature</i>, vol. 542, no. 7639, Springer Nature, 2017,
    pp. 43–48, doi:<a href="https://doi.org/10.1038/nature20818">10.1038/nature20818</a>.
  short: C. Chen, E. Itakura, G.M. Nelson, M. Sheng, P. Laurent, L.A. Fenk, R.A. Butcher,
    R.S. Hegde, M. de Bono, Nature 542 (2017) 43–48.
date_created: 2019-03-19T14:06:41Z
date_published: 2017-02-02T00:00:00Z
date_updated: 2021-01-12T08:06:12Z
day: '02'
doi: 10.1038/nature20818
extern: '1'
external_id:
  pmid:
  - '    28099418'
intvolume: '       542'
issue: '7639'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pubmed/28099418
month: '02'
oa: 1
oa_version: Submitted Version
page: 43-48
pmid: 1
publication: Nature
publication_identifier:
  issn:
  - 0028-0836
  - 1476-4687
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: IL-17 is a neuromodulator of Caenorhabditis elegans sensory responses
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 542
year: '2017'
...
---
_id: '613'
abstract:
- lang: eng
  text: 'Bacteria in groups vary individually, and interact with other bacteria and
    the environment to produce population-level patterns of gene expression. Investigating
    such behavior in detail requires measuring and controlling populations at the
    single-cell level alongside precisely specified interactions and environmental
    characteristics. Here we present an automated, programmable platform that combines
    image-based gene expression and growth measurements with on-line optogenetic expression
    control for hundreds of individual Escherichia coli cells over days, in a dynamically
    adjustable environment. This integrated platform broadly enables experiments that
    bridge individual and population behaviors. We demonstrate: (i) population structuring
    by independent closed-loop control of gene expression in many individual cells,
    (ii) cell-cell variation control during antibiotic perturbation, (iii) hybrid
    bio-digital circuits in single cells, and freely specifiable digital communication
    between individual bacteria. These examples showcase the potential for real-time
    integration of theoretical models with measurement and control of many individual
    cells to investigate and engineer microbial population behavior.'
acknowledgement: We are grateful to M. Lang, H. Janovjak, M. Khammash, A. Milias-Argeitis,
  M. Rullan, G. Batt, A. Bosma-Moody, Aryan, S. Leibler, and members of the Guet and
  Tkačik groups for helpful discussion, comments, and suggestions. We thank A. Moglich,
  T. Mathes, J. Tabor, and S. Schmidl for kind gifts of strains, and R. Hauschild,
  B. Knep, M. Lang, T. Asenov, E. Papusheva, T. Menner, T. Adletzberger, and J. Merrin
  for technical assistance. The research leading to these results has received funding
  from the People Programme (Marie Curie Actions) of the European Union’s Seventh
  Framework Programme (FP7/2007–2013) under REA grant agreement no. [291734]. (to
  R.C. and J.R.), Austrian Science Fund grant FWF P28844 (to G.T.), and internal IST
  Austria Interdisciplinary Project Support. J.R. acknowledges support from the Agence
  Nationale de la Recherche (ANR) under Grant Nos. ANR-16-CE33-0018 (MEMIP), ANR-16-CE12-0025
  (COGEX) and ANR-10-BINF-06-01 (ICEBERG).
article_number: '1535'
article_processing_charge: Yes (in subscription journal)
author:
- first_name: Remy P
  full_name: Chait, Remy P
  id: 3464AE84-F248-11E8-B48F-1D18A9856A87
  last_name: Chait
  orcid: 0000-0003-0876-3187
- first_name: Jakob
  full_name: Ruess, Jakob
  id: 4A245D00-F248-11E8-B48F-1D18A9856A87
  last_name: Ruess
  orcid: 0000-0003-1615-3282
- first_name: Tobias
  full_name: Bergmiller, Tobias
  id: 2C471CFA-F248-11E8-B48F-1D18A9856A87
  last_name: Bergmiller
  orcid: 0000-0001-5396-4346
- first_name: Gasper
  full_name: Tkacik, Gasper
  id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
  last_name: Tkacik
  orcid: 0000-0002-6699-1455
- first_name: Calin C
  full_name: Guet, Calin C
  id: 47F8433E-F248-11E8-B48F-1D18A9856A87
  last_name: Guet
  orcid: 0000-0001-6220-2052
citation:
  ama: Chait RP, Ruess J, Bergmiller T, Tkačik G, Guet CC. Shaping bacterial population
    behavior through computer interfaced control of individual cells. <i>Nature Communications</i>.
    2017;8(1). doi:<a href="https://doi.org/10.1038/s41467-017-01683-1">10.1038/s41467-017-01683-1</a>
  apa: Chait, R. P., Ruess, J., Bergmiller, T., Tkačik, G., &#38; Guet, C. C. (2017).
    Shaping bacterial population behavior through computer interfaced control of individual
    cells. <i>Nature Communications</i>. Nature Publishing Group. <a href="https://doi.org/10.1038/s41467-017-01683-1">https://doi.org/10.1038/s41467-017-01683-1</a>
  chicago: Chait, Remy P, Jakob Ruess, Tobias Bergmiller, Gašper Tkačik, and Calin
    C Guet. “Shaping Bacterial Population Behavior through Computer Interfaced Control
    of Individual Cells.” <i>Nature Communications</i>. Nature Publishing Group, 2017.
    <a href="https://doi.org/10.1038/s41467-017-01683-1">https://doi.org/10.1038/s41467-017-01683-1</a>.
  ieee: R. P. Chait, J. Ruess, T. Bergmiller, G. Tkačik, and C. C. Guet, “Shaping
    bacterial population behavior through computer interfaced control of individual
    cells,” <i>Nature Communications</i>, vol. 8, no. 1. Nature Publishing Group,
    2017.
  ista: Chait RP, Ruess J, Bergmiller T, Tkačik G, Guet CC. 2017. Shaping bacterial
    population behavior through computer interfaced control of individual cells. Nature
    Communications. 8(1), 1535.
  mla: Chait, Remy P., et al. “Shaping Bacterial Population Behavior through Computer
    Interfaced Control of Individual Cells.” <i>Nature Communications</i>, vol. 8,
    no. 1, 1535, Nature Publishing Group, 2017, doi:<a href="https://doi.org/10.1038/s41467-017-01683-1">10.1038/s41467-017-01683-1</a>.
  short: R.P. Chait, J. Ruess, T. Bergmiller, G. Tkačik, C.C. Guet, Nature Communications
    8 (2017).
date_created: 2018-12-11T11:47:30Z
date_published: 2017-12-01T00:00:00Z
date_updated: 2021-01-12T08:06:15Z
day: '01'
ddc:
- '576'
- '579'
department:
- _id: CaGu
- _id: GaTk
doi: 10.1038/s41467-017-01683-1
ec_funded: 1
file:
- access_level: open_access
  checksum: 44bb5d0229926c23a9955d9fe0f9723f
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:16:05Z
  date_updated: 2020-07-14T12:47:20Z
  file_id: '5190'
  file_name: IST-2017-911-v1+1_s41467-017-01683-1.pdf
  file_size: 1951699
  relation: main_file
file_date_updated: 2020-07-14T12:47:20Z
has_accepted_license: '1'
intvolume: '         8'
issue: '1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '12'
oa: 1
oa_version: Published Version
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
- _id: 254E9036-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P28844-B27
  name: Biophysics of information processing in gene regulation
publication: Nature Communications
publication_identifier:
  issn:
  - '20411723'
publication_status: published
publisher: Nature Publishing Group
publist_id: '7191'
pubrep_id: '911'
quality_controlled: '1'
scopus_import: 1
status: public
title: Shaping bacterial population behavior through computer interfaced control of
  individual cells
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2017'
...
---
_id: '614'
abstract:
- lang: eng
  text: 'Moths and butterflies (Lepidoptera) usually have a pair of differentiated
    WZ sex chromosomes. However, in most lineages outside of the division Ditrysia,
    as well as in the sister order Trichoptera, females lack a W chromosome. The W
    is therefore thought to have been acquired secondarily. Here we compare the genomes
    of three Lepidoptera species (one Dytrisia and two non-Dytrisia) to test three
    models accounting for the origin of the W: (1) a Z-autosome fusion; (2) a sex
    chromosome turnover; and (3) a non-canonical mechanism (e.g., through the recruitment
    of a B chromosome). We show that the gene content of the Z is highly conserved
    across Lepidoptera (rejecting a sex chromosome turnover) and that very few genes
    moved onto the Z in the common ancestor of the Ditrysia (arguing against a Z-autosome
    fusion). Our comparative genomics analysis therefore supports the secondary acquisition
    of the Lepidoptera W by a non-canonical mechanism, and it confirms the extreme
    stability of well-differentiated sex chromosomes.'
article_number: '1486'
article_processing_charge: No
article_type: original
author:
- first_name: Christelle
  full_name: Fraisse, Christelle
  id: 32DF5794-F248-11E8-B48F-1D18A9856A87
  last_name: Fraisse
  orcid: 0000-0001-8441-5075
- first_name: Marion A
  full_name: Picard, Marion A
  id: 2C921A7A-F248-11E8-B48F-1D18A9856A87
  last_name: Picard
  orcid: 0000-0002-8101-2518
- first_name: Beatriz
  full_name: Vicoso, Beatriz
  id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
  last_name: Vicoso
  orcid: 0000-0002-4579-8306
citation:
  ama: Fraisse C, Picard MAL, Vicoso B. The deep conservation of the Lepidoptera Z
    chromosome suggests a non canonical origin of the W. <i>Nature Communications</i>.
    2017;8(1). doi:<a href="https://doi.org/10.1038/s41467-017-01663-5">10.1038/s41467-017-01663-5</a>
  apa: Fraisse, C., Picard, M. A. L., &#38; Vicoso, B. (2017). The deep conservation
    of the Lepidoptera Z chromosome suggests a non canonical origin of the W. <i>Nature
    Communications</i>. Nature Publishing Group. <a href="https://doi.org/10.1038/s41467-017-01663-5">https://doi.org/10.1038/s41467-017-01663-5</a>
  chicago: Fraisse, Christelle, Marion A L Picard, and Beatriz Vicoso. “The Deep Conservation
    of the Lepidoptera Z Chromosome Suggests a Non Canonical Origin of the W.” <i>Nature
    Communications</i>. Nature Publishing Group, 2017. <a href="https://doi.org/10.1038/s41467-017-01663-5">https://doi.org/10.1038/s41467-017-01663-5</a>.
  ieee: C. Fraisse, M. A. L. Picard, and B. Vicoso, “The deep conservation of the
    Lepidoptera Z chromosome suggests a non canonical origin of the W,” <i>Nature
    Communications</i>, vol. 8, no. 1. Nature Publishing Group, 2017.
  ista: Fraisse C, Picard MAL, Vicoso B. 2017. The deep conservation of the Lepidoptera
    Z chromosome suggests a non canonical origin of the W. Nature Communications.
    8(1), 1486.
  mla: Fraisse, Christelle, et al. “The Deep Conservation of the Lepidoptera Z Chromosome
    Suggests a Non Canonical Origin of the W.” <i>Nature Communications</i>, vol.
    8, no. 1, 1486, Nature Publishing Group, 2017, doi:<a href="https://doi.org/10.1038/s41467-017-01663-5">10.1038/s41467-017-01663-5</a>.
  short: C. Fraisse, M.A.L. Picard, B. Vicoso, Nature Communications 8 (2017).
date_created: 2018-12-11T11:47:30Z
date_published: 2017-12-01T00:00:00Z
date_updated: 2024-02-21T13:47:47Z
day: '01'
ddc:
- '570'
- '576'
department:
- _id: BeVi
- _id: NiBa
doi: 10.1038/s41467-017-01663-5
external_id:
  pmid:
  - '29133797'
file:
- access_level: open_access
  checksum: 4da2651303c8afc2f7fc419be42a2433
  content_type: application/pdf
  creator: dernst
  date_created: 2020-03-03T15:55:50Z
  date_updated: 2020-07-14T12:47:20Z
  file_id: '7562'
  file_name: 2017_NatureComm_Fraisse.pdf
  file_size: 1201520
  relation: main_file
file_date_updated: 2020-07-14T12:47:20Z
has_accepted_license: '1'
intvolume: '         8'
issue: '1'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 250ED89C-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P28842-B22
  name: Sex chromosome evolution under male- and female- heterogamety
publication: Nature Communications
publication_identifier:
  issn:
  - '20411723'
publication_status: published
publisher: Nature Publishing Group
publist_id: '7190'
pubrep_id: '910'
quality_controlled: '1'
related_material:
  record:
  - id: '7163'
    relation: popular_science
    status: public
scopus_import: 1
status: public
title: The deep conservation of the Lepidoptera Z chromosome suggests a non canonical
  origin of the W
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2017'
...
---
_id: '615'
abstract:
- lang: eng
  text: We show that the Dyson Brownian Motion exhibits local universality after a
    very short time assuming that local rigidity and level repulsion of the eigenvalues
    hold. These conditions are verified, hence bulk spectral universality is proven,
    for a large class of Wigner-like matrices, including deformed Wigner ensembles
    and ensembles with non-stochastic variance matrices whose limiting densities differ
    from Wigner's semicircle law.
author:
- first_name: László
  full_name: Erdös, László
  id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
  last_name: Erdös
  orcid: 0000-0001-5366-9603
- first_name: Kevin
  full_name: Schnelli, Kevin
  id: 434AD0AE-F248-11E8-B48F-1D18A9856A87
  last_name: Schnelli
  orcid: 0000-0003-0954-3231
citation:
  ama: Erdös L, Schnelli K. Universality for random matrix flows with time dependent
    density. <i>Annales de l’institut Henri Poincare (B) Probability and Statistics</i>.
    2017;53(4):1606-1656. doi:<a href="https://doi.org/10.1214/16-AIHP765">10.1214/16-AIHP765</a>
  apa: Erdös, L., &#38; Schnelli, K. (2017). Universality for random matrix flows
    with time dependent density. <i>Annales de l’institut Henri Poincare (B) Probability
    and Statistics</i>. Institute of Mathematical Statistics. <a href="https://doi.org/10.1214/16-AIHP765">https://doi.org/10.1214/16-AIHP765</a>
  chicago: Erdös, László, and Kevin Schnelli. “Universality for Random Matrix Flows
    with Time Dependent Density.” <i>Annales de l’institut Henri Poincare (B) Probability
    and Statistics</i>. Institute of Mathematical Statistics, 2017. <a href="https://doi.org/10.1214/16-AIHP765">https://doi.org/10.1214/16-AIHP765</a>.
  ieee: L. Erdös and K. Schnelli, “Universality for random matrix flows with time
    dependent density,” <i>Annales de l’institut Henri Poincare (B) Probability and
    Statistics</i>, vol. 53, no. 4. Institute of Mathematical Statistics, pp. 1606–1656,
    2017.
  ista: Erdös L, Schnelli K. 2017. Universality for random matrix flows with time
    dependent density. Annales de l’institut Henri Poincare (B) Probability and Statistics.
    53(4), 1606–1656.
  mla: Erdös, László, and Kevin Schnelli. “Universality for Random Matrix Flows with
    Time Dependent Density.” <i>Annales de l’institut Henri Poincare (B) Probability
    and Statistics</i>, vol. 53, no. 4, Institute of Mathematical Statistics, 2017,
    pp. 1606–56, doi:<a href="https://doi.org/10.1214/16-AIHP765">10.1214/16-AIHP765</a>.
  short: L. Erdös, K. Schnelli, Annales de l’institut Henri Poincare (B) Probability
    and Statistics 53 (2017) 1606–1656.
date_created: 2018-12-11T11:47:30Z
date_published: 2017-11-01T00:00:00Z
date_updated: 2021-01-12T08:06:22Z
day: '01'
department:
- _id: LaEr
doi: 10.1214/16-AIHP765
ec_funded: 1
intvolume: '        53'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1504.00650
month: '11'
oa: 1
oa_version: Submitted Version
page: 1606 - 1656
project:
- _id: 258DCDE6-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '338804'
  name: Random matrices, universality and disordered quantum systems
publication: Annales de l'institut Henri Poincare (B) Probability and Statistics
publication_identifier:
  issn:
  - '02460203'
publication_status: published
publisher: Institute of Mathematical Statistics
publist_id: '7189'
quality_controlled: '1'
scopus_import: 1
status: public
title: Universality for random matrix flows with time dependent density
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 53
year: '2017'
...
---
_id: '618'
abstract:
- lang: eng
  text: 'Background: Increasing temperatures are predicted to strongly impact host-parasite
    interactions, but empirical tests are rare. Host species that are naturally exposed
    to a broad temperature spectrum offer the possibility to investigate the effects
    of elevated temperatures on hosts and parasites. Using three-spined sticklebacks,
    Gasterosteus aculeatus L., and tapeworms, Schistocephalus solidus (Müller, 1776),
    originating from a cold and a warm water site of a volcanic lake, we subjected
    sympatric and allopatric host-parasite combinations to cold and warm conditions
    in a fully crossed design. We predicted that warm temperatures would promote the
    development of the parasites, while the hosts might benefit from cooler temperatures.
    We further expected adaptations to the local temperature and mutual adaptations
    of local host-parasite pairs. Results: Overall, S. solidus parasites grew faster
    at warm temperatures and stickleback hosts at cold temperatures. On a finer scale,
    we observed that parasites were able to exploit their hosts more efficiently at
    the parasite’s temperature of origin. In contrast, host tolerance towards parasite
    infection was higher when sticklebacks were infected with parasites at the parasite’s
    ‘foreign’ temperature. Cold-origin sticklebacks tended to grow faster and parasite
    infection induced a stronger immune response. Conclusions: Our results suggest
    that increasing environmental temperatures promote the parasite rather than the
    host and that host tolerance is dependent on the interaction between parasite
    infection and temperature. Sticklebacks might use tolerance mechanisms towards
    parasite infection in combination with their high plasticity towards temperature
    changes to cope with increasing parasite infection pressures and rising temperatures.'
article_number: '52'
author:
- first_name: Frederik
  full_name: Franke, Frederik
  last_name: Franke
- first_name: Sophie
  full_name: Armitage, Sophie
  last_name: Armitage
- first_name: Megan
  full_name: Kutzer, Megan
  id: 29D0B332-F248-11E8-B48F-1D18A9856A87
  last_name: Kutzer
  orcid: 0000-0002-8696-6978
- first_name: Joachim
  full_name: Kurtz, Joachim
  last_name: Kurtz
- first_name: Jörn
  full_name: Scharsack, Jörn
  last_name: Scharsack
citation:
  ama: Franke F, Armitage S, Kutzer M, Kurtz J, Scharsack J. Environmental temperature
    variation influences fitness trade-offs in a fish-tapeworm association . <i>Parasites
    &#38; Vectors</i>. 2017;10(252). doi:<a href="https://doi.org/10.1186/s13071-017-2192-7">10.1186/s13071-017-2192-7</a>
  apa: Franke, F., Armitage, S., Kutzer, M., Kurtz, J., &#38; Scharsack, J. (2017).
    Environmental temperature variation influences fitness trade-offs in a fish-tapeworm
    association . <i>Parasites &#38; Vectors</i>. BioMed Central. <a href="https://doi.org/10.1186/s13071-017-2192-7">https://doi.org/10.1186/s13071-017-2192-7</a>
  chicago: Franke, Frederik, Sophie Armitage, Megan Kutzer, Joachim Kurtz, and Jörn
    Scharsack. “Environmental Temperature Variation Influences Fitness Trade-Offs
    in a Fish-Tapeworm Association .” <i>Parasites &#38; Vectors</i>. BioMed Central,
    2017. <a href="https://doi.org/10.1186/s13071-017-2192-7">https://doi.org/10.1186/s13071-017-2192-7</a>.
  ieee: F. Franke, S. Armitage, M. Kutzer, J. Kurtz, and J. Scharsack, “Environmental
    temperature variation influences fitness trade-offs in a fish-tapeworm association
    ,” <i>Parasites &#38; Vectors</i>, vol. 10, no. 252. BioMed Central, 2017.
  ista: Franke F, Armitage S, Kutzer M, Kurtz J, Scharsack J. 2017. Environmental
    temperature variation influences fitness trade-offs in a fish-tapeworm association
    . Parasites &#38; Vectors. 10(252), 52.
  mla: Franke, Frederik, et al. “Environmental Temperature Variation Influences Fitness
    Trade-Offs in a Fish-Tapeworm Association .” <i>Parasites &#38; Vectors</i>, vol.
    10, no. 252, 52, BioMed Central, 2017, doi:<a href="https://doi.org/10.1186/s13071-017-2192-7">10.1186/s13071-017-2192-7</a>.
  short: F. Franke, S. Armitage, M. Kutzer, J. Kurtz, J. Scharsack, Parasites &#38;
    Vectors 10 (2017).
date_created: 2018-12-11T11:47:31Z
date_published: 2017-06-02T00:00:00Z
date_updated: 2021-01-12T08:06:35Z
day: '02'
ddc:
- '570'
doi: 10.1186/s13071-017-2192-7
extern: '1'
file:
- access_level: open_access
  checksum: 742943377a38ee208108705b8e2f4dbf
  content_type: application/pdf
  creator: dernst
  date_created: 2019-01-21T13:45:36Z
  date_updated: 2020-07-14T12:47:22Z
  file_id: '5864'
  file_name: 2017_Parasites_Franke.pdf
  file_size: 671807
  relation: main_file
file_date_updated: 2020-07-14T12:47:22Z
has_accepted_license: '1'
intvolume: '        10'
issue: '252'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
publication: Parasites & Vectors
publication_identifier:
  issn:
  - '17563305'
publication_status: published
publisher: BioMed Central
publist_id: '7186'
quality_controlled: '1'
status: public
title: 'Environmental temperature variation influences fitness trade-offs in a fish-tapeworm
  association '
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 10
year: '2017'
...
---
_id: '6196'
abstract:
- lang: eng
  text: PMAC is a simple and parallel block-cipher mode of operation, which was introduced
    by Black and Rogaway at Eurocrypt 2002. If instantiated with a (pseudo)random
    permutation over n-bit strings, PMAC constitutes a provably secure variable input-length
    (pseudo)random function. For adversaries making q queries, each of length at most
    l (in n-bit blocks), and of total length σ ≤ ql, the original paper proves an
    upper bound on the distinguishing advantage of  Ο(σ2/2n), while the currently
    best bound is  Ο (qσ/2n).In this work we show that this bound is tight by giving
    an attack with advantage Ω (q2l/2n). In the PMAC construction one initially XORs
    a mask to every message block, where the mask for the ith block is computed as
    τi := γi·L, where L is a (secret) random value, and γi is the i-th codeword of
    the Gray code. Our attack applies more generally to any sequence of γi’s which
    contains a large coset of a subgroup of GF(2n). We then investigate if the security
    of PMAC can be further improved by using τi’s that are k-wise independent, for
    k > 1 (the original distribution is only 1-wise independent). We observe that
    the security of PMAC will not increase in general, even if the masks are chosen
    from a 2-wise independent distribution, and then prove that the security increases
    to O(q<2/2n), if the τi are 4-wise independent. Due to simple extension attacks,
    this is the best bound one can hope for, using any distribution on the masks.
    Whether 3-wise independence is already sufficient to get this level of security
    is left as an open problem.
author:
- first_name: Peter
  full_name: Gazi, Peter
  id: 3E0BFE38-F248-11E8-B48F-1D18A9856A87
  last_name: Gazi
- first_name: Krzysztof Z
  full_name: Pietrzak, Krzysztof Z
  id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
  last_name: Pietrzak
  orcid: 0000-0002-9139-1654
- first_name: Michal
  full_name: Rybar, Michal
  id: 2B3E3DE8-F248-11E8-B48F-1D18A9856A87
  last_name: Rybar
citation:
  ama: Gazi P, Pietrzak KZ, Rybar M. The exact security of PMAC. <i>IACR Transactions
    on Symmetric Cryptology</i>. 2017;2016(2):145-161. doi:<a href="https://doi.org/10.13154/TOSC.V2016.I2.145-161">10.13154/TOSC.V2016.I2.145-161</a>
  apa: Gazi, P., Pietrzak, K. Z., &#38; Rybar, M. (2017). The exact security of PMAC.
    <i>IACR Transactions on Symmetric Cryptology</i>. Ruhr University Bochum. <a href="https://doi.org/10.13154/TOSC.V2016.I2.145-161">https://doi.org/10.13154/TOSC.V2016.I2.145-161</a>
  chicago: Gazi, Peter, Krzysztof Z Pietrzak, and Michal Rybar. “The Exact Security
    of PMAC.” <i>IACR Transactions on Symmetric Cryptology</i>. Ruhr University Bochum,
    2017. <a href="https://doi.org/10.13154/TOSC.V2016.I2.145-161">https://doi.org/10.13154/TOSC.V2016.I2.145-161</a>.
  ieee: P. Gazi, K. Z. Pietrzak, and M. Rybar, “The exact security of PMAC,” <i>IACR
    Transactions on Symmetric Cryptology</i>, vol. 2016, no. 2. Ruhr University Bochum,
    pp. 145–161, 2017.
  ista: Gazi P, Pietrzak KZ, Rybar M. 2017. The exact security of PMAC. IACR Transactions
    on Symmetric Cryptology. 2016(2), 145–161.
  mla: Gazi, Peter, et al. “The Exact Security of PMAC.” <i>IACR Transactions on Symmetric
    Cryptology</i>, vol. 2016, no. 2, Ruhr University Bochum, 2017, pp. 145–61, doi:<a
    href="https://doi.org/10.13154/TOSC.V2016.I2.145-161">10.13154/TOSC.V2016.I2.145-161</a>.
  short: P. Gazi, K.Z. Pietrzak, M. Rybar, IACR Transactions on Symmetric Cryptology
    2016 (2017) 145–161.
date_created: 2019-04-04T13:48:23Z
date_published: 2017-02-03T00:00:00Z
date_updated: 2023-09-07T12:02:27Z
day: '03'
ddc:
- '000'
department:
- _id: KrPi
doi: 10.13154/TOSC.V2016.I2.145-161
ec_funded: 1
file:
- access_level: open_access
  checksum: f23161d685dd957ae8d7274132999684
  content_type: application/pdf
  creator: dernst
  date_created: 2019-04-04T13:53:58Z
  date_updated: 2020-07-14T12:47:24Z
  file_id: '6197'
  file_name: 2017_IACR_Gazi.pdf
  file_size: 597335
  relation: main_file
file_date_updated: 2020-07-14T12:47:24Z
has_accepted_license: '1'
intvolume: '      2016'
issue: '2'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
page: 145-161
project:
- _id: 258AA5B2-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '682815'
  name: Teaching Old Crypto New Tricks
publication: IACR Transactions on Symmetric Cryptology
publication_identifier:
  eissn:
  - 2519-173X
publication_status: published
publisher: Ruhr University Bochum
quality_controlled: '1'
related_material:
  record:
  - id: '838'
    relation: dissertation_contains
    status: public
status: public
title: The exact security of PMAC
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 2016
year: '2017'
...
---
_id: '621'
abstract:
- lang: eng
  text: The mammalian cerebral cortex is responsible for higher cognitive functions
    such as perception, consciousness, and acquiring and processing information. The
    neocortex is organized into six distinct laminae, each composed of a rich diversity
    of cell types which assemble into highly complex cortical circuits. Radial glia
    progenitors (RGPs) are responsible for producing all neocortical neurons and certain
    glia lineages. Here, we discuss recent discoveries emerging from clonal lineage
    analysis at the single RGP cell level that provide us with an inaugural quantitative
    framework of RGP lineage progression. We further discuss the importance of the
    relative contribution of intrinsic gene functions and non-cell-autonomous or community
    effects in regulating RGP proliferation behavior and lineage progression.
article_processing_charge: Yes (in subscription journal)
author:
- first_name: Robert J
  full_name: Beattie, Robert J
  id: 2E26DF60-F248-11E8-B48F-1D18A9856A87
  last_name: Beattie
  orcid: 0000-0002-8483-8753
- first_name: Simon
  full_name: Hippenmeyer, Simon
  id: 37B36620-F248-11E8-B48F-1D18A9856A87
  last_name: Hippenmeyer
  orcid: 0000-0003-2279-1061
citation:
  ama: Beattie RJ, Hippenmeyer S. Mechanisms of radial glia progenitor cell lineage
    progression. <i>FEBS letters</i>. 2017;591(24):3993-4008. doi:<a href="https://doi.org/10.1002/1873-3468.12906">10.1002/1873-3468.12906</a>
  apa: Beattie, R. J., &#38; Hippenmeyer, S. (2017). Mechanisms of radial glia progenitor
    cell lineage progression. <i>FEBS Letters</i>. Wiley-Blackwell. <a href="https://doi.org/10.1002/1873-3468.12906">https://doi.org/10.1002/1873-3468.12906</a>
  chicago: Beattie, Robert J, and Simon Hippenmeyer. “Mechanisms of Radial Glia Progenitor
    Cell Lineage Progression.” <i>FEBS Letters</i>. Wiley-Blackwell, 2017. <a href="https://doi.org/10.1002/1873-3468.12906">https://doi.org/10.1002/1873-3468.12906</a>.
  ieee: R. J. Beattie and S. Hippenmeyer, “Mechanisms of radial glia progenitor cell
    lineage progression,” <i>FEBS letters</i>, vol. 591, no. 24. Wiley-Blackwell,
    pp. 3993–4008, 2017.
  ista: Beattie RJ, Hippenmeyer S. 2017. Mechanisms of radial glia progenitor cell
    lineage progression. FEBS letters. 591(24), 3993–4008.
  mla: Beattie, Robert J., and Simon Hippenmeyer. “Mechanisms of Radial Glia Progenitor
    Cell Lineage Progression.” <i>FEBS Letters</i>, vol. 591, no. 24, Wiley-Blackwell,
    2017, pp. 3993–4008, doi:<a href="https://doi.org/10.1002/1873-3468.12906">10.1002/1873-3468.12906</a>.
  short: R.J. Beattie, S. Hippenmeyer, FEBS Letters 591 (2017) 3993–4008.
date_created: 2018-12-11T11:47:32Z
date_published: 2017-12-01T00:00:00Z
date_updated: 2024-02-14T12:02:08Z
day: '01'
ddc:
- '571'
- '610'
department:
- _id: SiHi
doi: 10.1002/1873-3468.12906
ec_funded: 1
external_id:
  pmid:
  - '29121403'
file:
- access_level: open_access
  checksum: a46dadc84e0c28d389dd3e9e954464db
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:16:24Z
  date_updated: 2020-07-14T12:47:24Z
  file_id: '5211'
  file_name: IST-2018-928-v1+1_Beattie_et_al-2017-FEBS_Letters.pdf
  file_size: 644149
  relation: main_file
file_date_updated: 2020-07-14T12:47:24Z
has_accepted_license: '1'
intvolume: '       591'
issue: '24'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc/4.0/
month: '12'
oa: 1
oa_version: Published Version
page: 3993  - 4008
pmid: 1
project:
- _id: 25D7962E-B435-11E9-9278-68D0E5697425
  grant_number: RGP0053/2014
  name: Quantitative Structure-Function Analysis of Cerebral Cortex Assembly at Clonal
    Level
- _id: 25D61E48-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '618444'
  name: Molecular Mechanisms of Cerebral Cortex Development
publication: FEBS letters
publication_identifier:
  issn:
  - '00145793'
publication_status: published
publisher: Wiley-Blackwell
publist_id: '7183'
pubrep_id: '928'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Mechanisms of radial glia progenitor cell lineage progression
tmp:
  image: /images/cc_by_nc.png
  legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
  short: CC BY-NC (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 591
year: '2017'
...
---
_id: '623'
abstract:
- lang: eng
  text: Genetic factors might be largely responsible for the development of autism
    spectrum disorder (ASD) that alone or in combination with specific environmental
    risk factors trigger the pathology. Multiple mutations identified in ASD patients
    that impair synaptic function in the central nervous system are well studied in
    animal models. How these mutations might interact with other risk factors is not
    fully understood though. Additionally, how systems outside of the brain are altered
    in the context of ASD is an emerging area of research. Extracerebral influences
    on the physiology could begin in utero and contribute to changes in the brain
    and in the development of other body systems and further lead to epigenetic changes.
    Therefore, multiple recent studies have aimed at elucidating the role of gene-environment
    interactions in ASD. Here we provide an overview on the extracerebral systems
    that might play an important associative role in ASD and review evidence regarding
    the potential roles of inflammation, trace metals, metabolism, genetic susceptibility,
    enteric nervous system function and the microbiota of the gastrointestinal (GI)
    tract on the development of endophenotypes in animal models of ASD. By influencing
    environmental conditions, it might be possible to reduce or limit the severity
    of ASD pathology.
alternative_title:
- ADVSANAT
author:
- first_name: Elisa
  full_name: Hill Yardin, Elisa
  last_name: Hill Yardin
- first_name: Sonja
  full_name: Mckeown, Sonja
  last_name: Mckeown
- first_name: Gaia
  full_name: Novarino, Gaia
  id: 3E57A680-F248-11E8-B48F-1D18A9856A87
  last_name: Novarino
  orcid: 0000-0002-7673-7178
- first_name: Andreas
  full_name: Grabrucker, Andreas
  last_name: Grabrucker
citation:
  ama: 'Hill Yardin E, Mckeown S, Novarino G, Grabrucker A. Extracerebral dysfunction
    in animal models of autism spectrum disorder. In: Schmeisser M, Boekers T, eds.
    <i>Translational Anatomy and Cell Biology of Autism Spectrum Disorder</i>. Vol
    224. Advances in Anatomy Embryology and Cell Biology. Springer; 2017:159-187.
    doi:<a href="https://doi.org/10.1007/978-3-319-52498-6_9">10.1007/978-3-319-52498-6_9</a>'
  apa: Hill Yardin, E., Mckeown, S., Novarino, G., &#38; Grabrucker, A. (2017). Extracerebral
    dysfunction in animal models of autism spectrum disorder. In M. Schmeisser &#38;
    T. Boekers (Eds.), <i>Translational Anatomy and Cell Biology of Autism Spectrum
    Disorder</i> (Vol. 224, pp. 159–187). Springer. <a href="https://doi.org/10.1007/978-3-319-52498-6_9">https://doi.org/10.1007/978-3-319-52498-6_9</a>
  chicago: Hill Yardin, Elisa, Sonja Mckeown, Gaia Novarino, and Andreas Grabrucker.
    “Extracerebral Dysfunction in Animal Models of Autism Spectrum Disorder.” In <i>Translational
    Anatomy and Cell Biology of Autism Spectrum Disorder</i>, edited by Michael Schmeisser
    and Tobias Boekers, 224:159–87. Advances in Anatomy Embryology and Cell Biology.
    Springer, 2017. <a href="https://doi.org/10.1007/978-3-319-52498-6_9">https://doi.org/10.1007/978-3-319-52498-6_9</a>.
  ieee: E. Hill Yardin, S. Mckeown, G. Novarino, and A. Grabrucker, “Extracerebral
    dysfunction in animal models of autism spectrum disorder,” in <i>Translational
    Anatomy and Cell Biology of Autism Spectrum Disorder</i>, vol. 224, M. Schmeisser
    and T. Boekers, Eds. Springer, 2017, pp. 159–187.
  ista: 'Hill Yardin E, Mckeown S, Novarino G, Grabrucker A. 2017.Extracerebral dysfunction
    in animal models of autism spectrum disorder. In: Translational Anatomy and Cell
    Biology of Autism Spectrum Disorder. ADVSANAT, vol. 224, 159–187.'
  mla: Hill Yardin, Elisa, et al. “Extracerebral Dysfunction in Animal Models of Autism
    Spectrum Disorder.” <i>Translational Anatomy and Cell Biology of Autism Spectrum
    Disorder</i>, edited by Michael Schmeisser and Tobias Boekers, vol. 224, Springer,
    2017, pp. 159–87, doi:<a href="https://doi.org/10.1007/978-3-319-52498-6_9">10.1007/978-3-319-52498-6_9</a>.
  short: E. Hill Yardin, S. Mckeown, G. Novarino, A. Grabrucker, in:, M. Schmeisser,
    T. Boekers (Eds.), Translational Anatomy and Cell Biology of Autism Spectrum Disorder,
    Springer, 2017, pp. 159–187.
date_created: 2018-12-11T11:47:33Z
date_published: 2017-05-28T00:00:00Z
date_updated: 2021-01-12T08:06:46Z
day: '28'
department:
- _id: GaNo
doi: 10.1007/978-3-319-52498-6_9
editor:
- first_name: Michael
  full_name: Schmeisser, Michael
  last_name: Schmeisser
- first_name: Tobias
  full_name: Boekers, Tobias
  last_name: Boekers
intvolume: '       224'
language:
- iso: eng
month: '05'
oa_version: None
page: 159 - 187
publication: Translational Anatomy and Cell Biology of Autism Spectrum Disorder
publication_identifier:
  isbn:
  - 978-3-319-52496-2
  issn:
  - '03015556'
publication_status: published
publisher: Springer
publist_id: '7177'
quality_controlled: '1'
scopus_import: 1
series_title: Advances in Anatomy Embryology and Cell Biology
status: public
title: Extracerebral dysfunction in animal models of autism spectrum disorder
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 224
year: '2017'
...
---
_id: '624'
abstract:
- lang: eng
  text: Bacteria adapt to adverse environmental conditions by altering gene expression
    patterns. Recently, a novel stress adaptation mechanism has been described that
    allows Escherichia coli to alter gene expression at the post-transcriptional level.
    The key player in this regulatory pathway is the endoribonuclease MazF, the toxin
    component of the toxin-antitoxin module mazEF that is triggered by various stressful
    conditions. In general, MazF degrades the majority of transcripts by cleaving
    at ACA sites, which results in the retardation of bacterial growth. Furthermore,
    MazF can process a small subset of mRNAs and render them leaderless by removing
    their ribosome binding site. MazF concomitantly modifies ribosomes, making them
    selective for the translation of leaderless mRNAs. In this study, we employed
    fluorescent reporter-systems to investigate mazEF expression during stressful
    conditions, and to infer consequences of the mRNA processing mediated by MazF
    on gene expression at the single-cell level. Our results suggest that mazEF transcription
    is maintained at low levels in single cells encountering adverse conditions, such
    as antibiotic stress or amino acid starvation. Moreover, using the grcA mRNA as
    a model for MazF-mediated mRNA processing, we found that MazF activation promotes
    heterogeneity in the grcA reporter expression, resulting in a subpopulation of
    cells with increased levels of GrcA reporter protein.
acknowledgement: 'Austrian Science Fund (FWF): M1697, P22249; Swiss National Science
  Foundation (SNF): 145706; European Commission;FWF Special Research Program: RNA-REG
  F43'
article_number: '3830'
author:
- first_name: Nela
  full_name: Nikolic, Nela
  id: 42D9CABC-F248-11E8-B48F-1D18A9856A87
  last_name: Nikolic
  orcid: 0000-0001-9068-6090
- first_name: Zrinka
  full_name: Didara, Zrinka
  last_name: Didara
- first_name: Isabella
  full_name: Moll, Isabella
  last_name: Moll
citation:
  ama: Nikolic N, Didara Z, Moll I. MazF activation promotes translational heterogeneity
    of the grcA mRNA in Escherichia coli populations. <i>PeerJ</i>. 2017;2017(9).
    doi:<a href="https://doi.org/10.7717/peerj.3830">10.7717/peerj.3830</a>
  apa: Nikolic, N., Didara, Z., &#38; Moll, I. (2017). MazF activation promotes translational
    heterogeneity of the grcA mRNA in Escherichia coli populations. <i>PeerJ</i>.
    PeerJ. <a href="https://doi.org/10.7717/peerj.3830">https://doi.org/10.7717/peerj.3830</a>
  chicago: Nikolic, Nela, Zrinka Didara, and Isabella Moll. “MazF Activation Promotes
    Translational Heterogeneity of the GrcA MRNA in Escherichia Coli Populations.”
    <i>PeerJ</i>. PeerJ, 2017. <a href="https://doi.org/10.7717/peerj.3830">https://doi.org/10.7717/peerj.3830</a>.
  ieee: N. Nikolic, Z. Didara, and I. Moll, “MazF activation promotes translational
    heterogeneity of the grcA mRNA in Escherichia coli populations,” <i>PeerJ</i>,
    vol. 2017, no. 9. PeerJ, 2017.
  ista: Nikolic N, Didara Z, Moll I. 2017. MazF activation promotes translational
    heterogeneity of the grcA mRNA in Escherichia coli populations. PeerJ. 2017(9),
    3830.
  mla: Nikolic, Nela, et al. “MazF Activation Promotes Translational Heterogeneity
    of the GrcA MRNA in Escherichia Coli Populations.” <i>PeerJ</i>, vol. 2017, no.
    9, 3830, PeerJ, 2017, doi:<a href="https://doi.org/10.7717/peerj.3830">10.7717/peerj.3830</a>.
  short: N. Nikolic, Z. Didara, I. Moll, PeerJ 2017 (2017).
date_created: 2018-12-11T11:47:33Z
date_published: 2017-09-21T00:00:00Z
date_updated: 2021-01-12T08:06:48Z
day: '21'
ddc:
- '579'
department:
- _id: CaGu
doi: 10.7717/peerj.3830
file:
- access_level: open_access
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title: MazF activation promotes translational heterogeneity of the grcA mRNA in Escherichia
  coli populations
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
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type: journal_article
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volume: 2017
year: '2017'
...
---
_id: '625'
abstract:
- lang: eng
  text: In the analysis of reactive systems a quantitative objective assigns a real
    value to every trace of the system. The value decision problem for a quantitative
    objective requires a trace whose value is at least a given threshold, and the
    exact value decision problem requires a trace whose value is exactly the threshold.
    We compare the computational complexity of the value and exact value decision
    problems for classical quantitative objectives, such as sum, discounted sum, energy,
    and mean-payoff for two standard models of reactive systems, namely, graphs and
    graph games.
acknowledgement: 'This research was supported in part by the Austrian Science Fund
  (FWF) under grants S11402-N23 and S11407-N23 (RiSE/SHiNE), and Z211-N23 (Wittgenstein
  Award), ERC Start grant (279307: Graph Games), Vienna Science and Technology Fund
  (WWTF) through project ICT15-003.'
alternative_title:
- LNCS
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author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Laurent
  full_name: Doyen, Laurent
  last_name: Doyen
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
citation:
  ama: 'Chatterjee K, Doyen L, Henzinger TA. The cost of exactness in quantitative
    reachability. In: Aceto L, Bacci G, Ingólfsdóttir A, Legay A, Mardare R, eds.
    <i>Models, Algorithms, Logics and Tools</i>. Vol 10460. Theoretical Computer Science
    and General Issues. Springer; 2017:367-381. doi:<a href="https://doi.org/10.1007/978-3-319-63121-9_18">10.1007/978-3-319-63121-9_18</a>'
  apa: Chatterjee, K., Doyen, L., &#38; Henzinger, T. A. (2017). The cost of exactness
    in quantitative reachability. In L. Aceto, G. Bacci, A. Ingólfsdóttir, A. Legay,
    &#38; R. Mardare (Eds.), <i>Models, Algorithms, Logics and Tools</i> (Vol. 10460,
    pp. 367–381). Springer. <a href="https://doi.org/10.1007/978-3-319-63121-9_18">https://doi.org/10.1007/978-3-319-63121-9_18</a>
  chicago: Chatterjee, Krishnendu, Laurent Doyen, and Thomas A Henzinger. “The Cost
    of Exactness in Quantitative Reachability.” In <i>Models, Algorithms, Logics and
    Tools</i>, edited by Luca Aceto, Giorgio Bacci, Anna Ingólfsdóttir, Axel Legay,
    and Radu Mardare, 10460:367–81. Theoretical Computer Science and General Issues.
    Springer, 2017. <a href="https://doi.org/10.1007/978-3-319-63121-9_18">https://doi.org/10.1007/978-3-319-63121-9_18</a>.
  ieee: K. Chatterjee, L. Doyen, and T. A. Henzinger, “The cost of exactness in quantitative
    reachability,” in <i>Models, Algorithms, Logics and Tools</i>, vol. 10460, L.
    Aceto, G. Bacci, A. Ingólfsdóttir, A. Legay, and R. Mardare, Eds. Springer, 2017,
    pp. 367–381.
  ista: 'Chatterjee K, Doyen L, Henzinger TA. 2017.The cost of exactness in quantitative
    reachability. In: Models, Algorithms, Logics and Tools. LNCS, vol. 10460, 367–381.'
  mla: Chatterjee, Krishnendu, et al. “The Cost of Exactness in Quantitative Reachability.”
    <i>Models, Algorithms, Logics and Tools</i>, edited by Luca Aceto et al., vol.
    10460, Springer, 2017, pp. 367–81, doi:<a href="https://doi.org/10.1007/978-3-319-63121-9_18">10.1007/978-3-319-63121-9_18</a>.
  short: K. Chatterjee, L. Doyen, T.A. Henzinger, in:, L. Aceto, G. Bacci, A. Ingólfsdóttir,
    A. Legay, R. Mardare (Eds.), Models, Algorithms, Logics and Tools, Springer, 2017,
    pp. 367–381.
date_created: 2018-12-11T11:47:34Z
date_published: 2017-07-25T00:00:00Z
date_updated: 2025-06-02T08:53:45Z
day: '25'
ddc:
- '000'
department:
- _id: KrCh
- _id: ToHe
doi: 10.1007/978-3-319-63121-9_18
ec_funded: 1
editor:
- first_name: Luca
  full_name: Aceto, Luca
  last_name: Aceto
- first_name: Giorgio
  full_name: Bacci, Giorgio
  last_name: Bacci
- first_name: Anna
  full_name: Ingólfsdóttir, Anna
  last_name: Ingólfsdóttir
- first_name: Axel
  full_name: Legay, Axel
  last_name: Legay
- first_name: Radu
  full_name: Mardare, Radu
  last_name: Mardare
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oa_version: Submitted Version
page: 367 - 381
project:
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  call_identifier: FWF
  grant_number: S11402-N23
  name: Moderne Concurrency Paradigms
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  grant_number: Z211
  name: The Wittgenstein Prize
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  call_identifier: FP7
  grant_number: '279307'
  name: 'Quantitative Graph Games: Theory and Applications'
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  grant_number: ICT15-003
  name: Efficient Algorithms for Computer Aided Verification
publication: Models, Algorithms, Logics and Tools
publication_identifier:
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  issn:
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series_title: Theoretical Computer Science and General Issues
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title: The cost of exactness in quantitative reachability
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user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 10460
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...
