---
_id: '9813'
abstract:
- lang: eng
  text: 'File S1 contains figures that clarify the following features: (i) effect
    of population size on the average number/frequency of SI classes, (ii) changes
    in the minimal completeness deficit in time for a single class, and (iii) diversification
    diagrams for all studied pathways, including the summary figure for k = 8. File
    S2 contains the code required for a stochastic simulation of the SLF system with
    an example. This file also includes the output in the form of figures and tables.'
article_processing_charge: No
author:
- first_name: Katarína
  full_name: Bod'ová, Katarína
  id: 2BA24EA0-F248-11E8-B48F-1D18A9856A87
  last_name: Bod'ová
  orcid: 0000-0002-7214-0171
- first_name: Tadeas
  full_name: Priklopil, Tadeas
  id: 3C869AA0-F248-11E8-B48F-1D18A9856A87
  last_name: Priklopil
- first_name: David
  full_name: Field, David
  id: 419049E2-F248-11E8-B48F-1D18A9856A87
  last_name: Field
  orcid: 0000-0002-4014-8478
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Melinda
  full_name: Pickup, Melinda
  id: 2C78037E-F248-11E8-B48F-1D18A9856A87
  last_name: Pickup
  orcid: 0000-0001-6118-0541
citation:
  ama: Bodova K, Priklopil T, Field D, Barton NH, Pickup M. Supplemental material
    for Bodova et al., 2018. 2018. doi:<a href="https://doi.org/10.25386/genetics.6148304.v1">10.25386/genetics.6148304.v1</a>
  apa: Bodova, K., Priklopil, T., Field, D., Barton, N. H., &#38; Pickup, M. (2018).
    Supplemental material for Bodova et al., 2018. Genetics Society of America. <a
    href="https://doi.org/10.25386/genetics.6148304.v1">https://doi.org/10.25386/genetics.6148304.v1</a>
  chicago: Bodova, Katarina, Tadeas Priklopil, David Field, Nicholas H Barton, and
    Melinda Pickup. “Supplemental Material for Bodova et Al., 2018.” Genetics Society
    of America, 2018. <a href="https://doi.org/10.25386/genetics.6148304.v1">https://doi.org/10.25386/genetics.6148304.v1</a>.
  ieee: K. Bodova, T. Priklopil, D. Field, N. H. Barton, and M. Pickup, “Supplemental
    material for Bodova et al., 2018.” Genetics Society of America, 2018.
  ista: Bodova K, Priklopil T, Field D, Barton NH, Pickup M. 2018. Supplemental material
    for Bodova et al., 2018, Genetics Society of America, <a href="https://doi.org/10.25386/genetics.6148304.v1">10.25386/genetics.6148304.v1</a>.
  mla: Bodova, Katarina, et al. <i>Supplemental Material for Bodova et Al., 2018</i>.
    Genetics Society of America, 2018, doi:<a href="https://doi.org/10.25386/genetics.6148304.v1">10.25386/genetics.6148304.v1</a>.
  short: K. Bodova, T. Priklopil, D. Field, N.H. Barton, M. Pickup, (2018).
date_created: 2021-08-06T13:04:32Z
date_published: 2018-04-30T00:00:00Z
date_updated: 2025-05-28T11:57:01Z
day: '30'
department:
- _id: NiBa
- _id: GaTk
doi: 10.25386/genetics.6148304.v1
main_file_link:
- open_access: '1'
  url: https://doi.org/10.25386/genetics.6148304.v1
month: '04'
oa: 1
oa_version: Published Version
publisher: Genetics Society of America
related_material:
  record:
  - id: '316'
    relation: used_in_publication
    status: public
status: public
title: Supplemental material for Bodova et al., 2018
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2018'
...
---
_id: '9831'
abstract:
- lang: eng
  text: 'Implementation of the inference method in Matlab, including three applications
    of the method: The first one for the model of ant motion, the second one for bacterial
    chemotaxis, and the third one for the motion of fish.'
article_processing_charge: No
author:
- first_name: Katarína
  full_name: Bod’Ová, Katarína
  last_name: Bod’Ová
- first_name: Gabriel
  full_name: Mitchell, Gabriel
  id: 315BCD80-F248-11E8-B48F-1D18A9856A87
  last_name: Mitchell
- first_name: Roy
  full_name: Harpaz, Roy
  last_name: Harpaz
- first_name: Elad
  full_name: Schneidman, Elad
  last_name: Schneidman
- first_name: Gašper
  full_name: Tkačik, Gašper
  id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
  last_name: Tkačik
  orcid: 0000-0002-6699-1455
citation:
  ama: Bod’Ová K, Mitchell G, Harpaz R, Schneidman E, Tkačik G. Implementation of
    the inference method in Matlab. 2018. doi:<a href="https://doi.org/10.1371/journal.pone.0193049.s001">10.1371/journal.pone.0193049.s001</a>
  apa: Bod’Ová, K., Mitchell, G., Harpaz, R., Schneidman, E., &#38; Tkačik, G. (2018).
    Implementation of the inference method in Matlab. Public Library of Science. <a
    href="https://doi.org/10.1371/journal.pone.0193049.s001">https://doi.org/10.1371/journal.pone.0193049.s001</a>
  chicago: Bod’Ová, Katarína, Gabriel Mitchell, Roy Harpaz, Elad Schneidman, and Gašper
    Tkačik. “Implementation of the Inference Method in Matlab.” Public Library of
    Science, 2018. <a href="https://doi.org/10.1371/journal.pone.0193049.s001">https://doi.org/10.1371/journal.pone.0193049.s001</a>.
  ieee: K. Bod’Ová, G. Mitchell, R. Harpaz, E. Schneidman, and G. Tkačik, “Implementation
    of the inference method in Matlab.” Public Library of Science, 2018.
  ista: Bod’Ová K, Mitchell G, Harpaz R, Schneidman E, Tkačik G. 2018. Implementation
    of the inference method in Matlab, Public Library of Science, <a href="https://doi.org/10.1371/journal.pone.0193049.s001">10.1371/journal.pone.0193049.s001</a>.
  mla: Bod’Ová, Katarína, et al. <i>Implementation of the Inference Method in Matlab</i>.
    Public Library of Science, 2018, doi:<a href="https://doi.org/10.1371/journal.pone.0193049.s001">10.1371/journal.pone.0193049.s001</a>.
  short: K. Bod’Ová, G. Mitchell, R. Harpaz, E. Schneidman, G. Tkačik, (2018).
date_created: 2021-08-09T07:01:24Z
date_published: 2018-03-07T00:00:00Z
date_updated: 2023-09-15T12:06:18Z
day: '07'
department:
- _id: GaTk
doi: 10.1371/journal.pone.0193049.s001
month: '03'
oa_version: Published Version
publisher: Public Library of Science
related_material:
  record:
  - id: '406'
    relation: used_in_publication
    status: public
status: public
title: Implementation of the inference method in Matlab
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2018'
...
---
_id: '9837'
abstract:
- lang: eng
  text: Both classical and recent studies suggest that chromosomal inversion polymorphisms
    are important in adaptation and speciation. However, biases in discovery and reporting
    of inversions make it difficult to assess their prevalence and biological importance.
    Here, we use an approach based on linkage disequilibrium among markers genotyped
    for samples collected across a transect between contrasting habitats to detect
    chromosomal rearrangements de novo. We report 17 polymorphic rearrangements in
    a single locality for the coastal marine snail, Littorina saxatilis. Patterns
    of diversity in the field and of recombination in controlled crosses provide strong
    evidence that at least the majority of these rearrangements are inversions. Most
    show clinal changes in frequency between habitats, suggestive of divergent selection,
    but only one appears to be fixed for different arrangements in the two habitats.
    Consistent with widespread evidence for balancing selection on inversion polymorphisms,
    we argue that a combination of heterosis and divergent selection can explain the
    observed patterns and should be considered in other systems spanning environmental
    gradients.
article_processing_charge: No
author:
- first_name: Rui
  full_name: Faria, Rui
  last_name: Faria
- first_name: Pragya
  full_name: Chaube, Pragya
  last_name: Chaube
- first_name: Hernán E.
  full_name: Morales, Hernán E.
  last_name: Morales
- first_name: Tomas
  full_name: Larsson, Tomas
  last_name: Larsson
- first_name: Alan R.
  full_name: Lemmon, Alan R.
  last_name: Lemmon
- first_name: Emily M.
  full_name: Lemmon, Emily M.
  last_name: Lemmon
- first_name: Marina
  full_name: Rafajlović, Marina
  last_name: Rafajlović
- first_name: Marina
  full_name: Panova, Marina
  last_name: Panova
- first_name: Mark
  full_name: Ravinet, Mark
  last_name: Ravinet
- first_name: Kerstin
  full_name: Johannesson, Kerstin
  last_name: Johannesson
- first_name: Anja M
  full_name: Westram, Anja M
  id: 3C147470-F248-11E8-B48F-1D18A9856A87
  last_name: Westram
  orcid: 0000-0003-1050-4969
- first_name: Roger K.
  full_name: Butlin, Roger K.
  last_name: Butlin
citation:
  ama: 'Faria R, Chaube P, Morales HE, et al. Data from: Multiple chromosomal rearrangements
    in a hybrid zone between Littorina saxatilis ecotypes. 2018. doi:<a href="https://doi.org/10.5061/dryad.72cg113">10.5061/dryad.72cg113</a>'
  apa: 'Faria, R., Chaube, P., Morales, H. E., Larsson, T., Lemmon, A. R., Lemmon,
    E. M., … Butlin, R. K. (2018). Data from: Multiple chromosomal rearrangements
    in a hybrid zone between Littorina saxatilis ecotypes. Dryad. <a href="https://doi.org/10.5061/dryad.72cg113">https://doi.org/10.5061/dryad.72cg113</a>'
  chicago: 'Faria, Rui, Pragya Chaube, Hernán E. Morales, Tomas Larsson, Alan R. Lemmon,
    Emily M. Lemmon, Marina Rafajlović, et al. “Data from: Multiple Chromosomal Rearrangements
    in a Hybrid Zone between Littorina Saxatilis Ecotypes.” Dryad, 2018. <a href="https://doi.org/10.5061/dryad.72cg113">https://doi.org/10.5061/dryad.72cg113</a>.'
  ieee: 'R. Faria <i>et al.</i>, “Data from: Multiple chromosomal rearrangements in
    a hybrid zone between Littorina saxatilis ecotypes.” Dryad, 2018.'
  ista: 'Faria R, Chaube P, Morales HE, Larsson T, Lemmon AR, Lemmon EM, Rafajlović
    M, Panova M, Ravinet M, Johannesson K, Westram AM, Butlin RK. 2018. Data from:
    Multiple chromosomal rearrangements in a hybrid zone between Littorina saxatilis
    ecotypes, Dryad, <a href="https://doi.org/10.5061/dryad.72cg113">10.5061/dryad.72cg113</a>.'
  mla: 'Faria, Rui, et al. <i>Data from: Multiple Chromosomal Rearrangements in a
    Hybrid Zone between Littorina Saxatilis Ecotypes</i>. Dryad, 2018, doi:<a href="https://doi.org/10.5061/dryad.72cg113">10.5061/dryad.72cg113</a>.'
  short: R. Faria, P. Chaube, H.E. Morales, T. Larsson, A.R. Lemmon, E.M. Lemmon,
    M. Rafajlović, M. Panova, M. Ravinet, K. Johannesson, A.M. Westram, R.K. Butlin,
    (2018).
date_created: 2021-08-09T12:46:39Z
date_published: 2018-10-09T00:00:00Z
date_updated: 2023-08-24T14:50:26Z
day: '09'
department:
- _id: NiBa
doi: 10.5061/dryad.72cg113
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5061/dryad.72cg113
month: '10'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
  record:
  - id: '6095'
    relation: used_in_publication
    status: public
status: public
title: 'Data from: Multiple chromosomal rearrangements in a hybrid zone between Littorina
  saxatilis ecotypes'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2018'
...
---
_id: '9838'
abstract:
- lang: eng
  text: 'Facial shape is the basis for facial recognition and categorization. Facial
    features reflect the underlying geometry of the skeletal structures. Here we reveal
    that cartilaginous nasal capsule (corresponding to upper jaw and face) is shaped
    by signals generated by neural structures: brain and olfactory epithelium. Brain-derived
    Sonic Hedgehog (SHH) enables the induction of nasal septum and posterior nasal
    capsule, whereas the formation of a capsule roof is controlled by signals from
    the olfactory epithelium. Unexpectedly, the cartilage of the nasal capsule turned
    out to be important for shaping membranous facial bones during development. This
    suggests that conserved neurosensory structures could benefit from protection
    and have evolved signals inducing cranial cartilages encasing them. Experiments
    with mutant mice revealed that the genomic regulatory regions controlling production
    of SHH in the nervous system contribute to facial cartilage morphogenesis, which
    might be a mechanism responsible for the adaptive evolution of animal faces and
    snouts.'
article_processing_charge: No
author:
- first_name: Marketa
  full_name: Kaucka, Marketa
  last_name: Kaucka
- first_name: Julian
  full_name: Petersen, Julian
  last_name: Petersen
- first_name: Marketa
  full_name: Tesarova, Marketa
  last_name: Tesarova
- first_name: Bara
  full_name: Szarowska, Bara
  last_name: Szarowska
- first_name: Maria Eleni
  full_name: Kastriti, Maria Eleni
  last_name: Kastriti
- first_name: Meng
  full_name: Xie, Meng
  last_name: Xie
- first_name: Anna
  full_name: Kicheva, Anna
  id: 3959A2A0-F248-11E8-B48F-1D18A9856A87
  last_name: Kicheva
  orcid: 0000-0003-4509-4998
- first_name: Karl
  full_name: Annusver, Karl
  last_name: Annusver
- first_name: Maria
  full_name: Kasper, Maria
  last_name: Kasper
- first_name: Orsolya
  full_name: Symmons, Orsolya
  last_name: Symmons
- first_name: Leslie
  full_name: Pan, Leslie
  last_name: Pan
- first_name: Francois
  full_name: Spitz, Francois
  last_name: Spitz
- first_name: Jozef
  full_name: Kaiser, Jozef
  last_name: Kaiser
- first_name: Maria
  full_name: Hovorakova, Maria
  last_name: Hovorakova
- first_name: Tomas
  full_name: Zikmund, Tomas
  last_name: Zikmund
- first_name: Kazunori
  full_name: Sunadome, Kazunori
  last_name: Sunadome
- first_name: Michael P
  full_name: Matise, Michael P
  last_name: Matise
- first_name: Hui
  full_name: Wang, Hui
  last_name: Wang
- first_name: Ulrika
  full_name: Marklund, Ulrika
  last_name: Marklund
- first_name: Hind
  full_name: Abdo, Hind
  last_name: Abdo
- first_name: Patrik
  full_name: Ernfors, Patrik
  last_name: Ernfors
- first_name: Pascal
  full_name: Maire, Pascal
  last_name: Maire
- first_name: Maud
  full_name: Wurmser, Maud
  last_name: Wurmser
- first_name: Andrei S
  full_name: Chagin, Andrei S
  last_name: Chagin
- first_name: Kaj
  full_name: Fried, Kaj
  last_name: Fried
- first_name: Igor
  full_name: Adameyko, Igor
  last_name: Adameyko
citation:
  ama: 'Kaucka M, Petersen J, Tesarova M, et al. Data from: Signals from the brain
    and olfactory epithelium control shaping of the mammalian nasal capsule cartilage.
    2018. doi:<a href="https://doi.org/10.5061/dryad.f1s76f2">10.5061/dryad.f1s76f2</a>'
  apa: 'Kaucka, M., Petersen, J., Tesarova, M., Szarowska, B., Kastriti, M. E., Xie,
    M., … Adameyko, I. (2018). Data from: Signals from the brain and olfactory epithelium
    control shaping of the mammalian nasal capsule cartilage. Dryad. <a href="https://doi.org/10.5061/dryad.f1s76f2">https://doi.org/10.5061/dryad.f1s76f2</a>'
  chicago: 'Kaucka, Marketa, Julian Petersen, Marketa Tesarova, Bara Szarowska, Maria
    Eleni Kastriti, Meng Xie, Anna Kicheva, et al. “Data from: Signals from the Brain
    and Olfactory Epithelium Control Shaping of the Mammalian Nasal Capsule Cartilage.”
    Dryad, 2018. <a href="https://doi.org/10.5061/dryad.f1s76f2">https://doi.org/10.5061/dryad.f1s76f2</a>.'
  ieee: 'M. Kaucka <i>et al.</i>, “Data from: Signals from the brain and olfactory
    epithelium control shaping of the mammalian nasal capsule cartilage.” Dryad, 2018.'
  ista: 'Kaucka M, Petersen J, Tesarova M, Szarowska B, Kastriti ME, Xie M, Kicheva
    A, Annusver K, Kasper M, Symmons O, Pan L, Spitz F, Kaiser J, Hovorakova M, Zikmund
    T, Sunadome K, Matise MP, Wang H, Marklund U, Abdo H, Ernfors P, Maire P, Wurmser
    M, Chagin AS, Fried K, Adameyko I. 2018. Data from: Signals from the brain and
    olfactory epithelium control shaping of the mammalian nasal capsule cartilage,
    Dryad, <a href="https://doi.org/10.5061/dryad.f1s76f2">10.5061/dryad.f1s76f2</a>.'
  mla: 'Kaucka, Marketa, et al. <i>Data from: Signals from the Brain and Olfactory
    Epithelium Control Shaping of the Mammalian Nasal Capsule Cartilage</i>. Dryad,
    2018, doi:<a href="https://doi.org/10.5061/dryad.f1s76f2">10.5061/dryad.f1s76f2</a>.'
  short: M. Kaucka, J. Petersen, M. Tesarova, B. Szarowska, M.E. Kastriti, M. Xie,
    A. Kicheva, K. Annusver, M. Kasper, O. Symmons, L. Pan, F. Spitz, J. Kaiser, M.
    Hovorakova, T. Zikmund, K. Sunadome, M.P. Matise, H. Wang, U. Marklund, H. Abdo,
    P. Ernfors, P. Maire, M. Wurmser, A.S. Chagin, K. Fried, I. Adameyko, (2018).
date_created: 2021-08-09T12:54:35Z
date_published: 2018-06-14T00:00:00Z
date_updated: 2023-09-18T09:29:07Z
day: '14'
department:
- _id: AnKi
doi: 10.5061/dryad.f1s76f2
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5061/dryad.f1s76f2
month: '06'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
  record:
  - id: '162'
    relation: used_in_publication
    status: public
status: public
title: 'Data from: Signals from the brain and olfactory epithelium control shaping
  of the mammalian nasal capsule cartilage'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2018'
...
---
_id: '9840'
abstract:
- lang: eng
  text: Herd immunity, a process in which resistant individuals limit the spread of
    a pathogen among susceptible hosts has been extensively studied in eukaryotes.
    Even though bacteria have evolved multiple immune systems against their phage
    pathogens, herd immunity in bacteria remains unexplored. Here we experimentally
    demonstrate that herd immunity arises during phage epidemics in structured and
    unstructured Escherichia coli populations consisting of differing frequencies
    of susceptible and resistant cells harboring CRISPR immunity. In addition, we
    develop a mathematical model that quantifies how herd immunity is affected by
    spatial population structure, bacterial growth rate, and phage replication rate.
    Using our model we infer a general epidemiological rule describing the relative
    speed of an epidemic in partially resistant spatially structured populations.
    Our experimental and theoretical findings indicate that herd immunity may be important
    in bacterial communities, allowing for stable coexistence of bacteria and their
    phages and the maintenance of polymorphism in bacterial immunity.
article_processing_charge: No
author:
- first_name: Pavel
  full_name: Payne, Pavel
  id: 35F78294-F248-11E8-B48F-1D18A9856A87
  last_name: Payne
  orcid: 0000-0002-2711-9453
- first_name: Lukas
  full_name: Geyrhofer, Lukas
  last_name: Geyrhofer
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Jonathan P
  full_name: Bollback, Jonathan P
  id: 2C6FA9CC-F248-11E8-B48F-1D18A9856A87
  last_name: Bollback
  orcid: 0000-0002-4624-4612
citation:
  ama: 'Payne P, Geyrhofer L, Barton NH, Bollback JP. Data from: CRISPR-based herd
    immunity limits phage epidemics in bacterial populations. 2018. doi:<a href="https://doi.org/10.5061/dryad.42n44">10.5061/dryad.42n44</a>'
  apa: 'Payne, P., Geyrhofer, L., Barton, N. H., &#38; Bollback, J. P. (2018). Data
    from: CRISPR-based herd immunity limits phage epidemics in bacterial populations.
    Dryad. <a href="https://doi.org/10.5061/dryad.42n44">https://doi.org/10.5061/dryad.42n44</a>'
  chicago: 'Payne, Pavel, Lukas Geyrhofer, Nicholas H Barton, and Jonathan P Bollback.
    “Data from: CRISPR-Based Herd Immunity Limits Phage Epidemics in Bacterial Populations.”
    Dryad, 2018. <a href="https://doi.org/10.5061/dryad.42n44">https://doi.org/10.5061/dryad.42n44</a>.'
  ieee: 'P. Payne, L. Geyrhofer, N. H. Barton, and J. P. Bollback, “Data from: CRISPR-based
    herd immunity limits phage epidemics in bacterial populations.” Dryad, 2018.'
  ista: 'Payne P, Geyrhofer L, Barton NH, Bollback JP. 2018. Data from: CRISPR-based
    herd immunity limits phage epidemics in bacterial populations, Dryad, <a href="https://doi.org/10.5061/dryad.42n44">10.5061/dryad.42n44</a>.'
  mla: 'Payne, Pavel, et al. <i>Data from: CRISPR-Based Herd Immunity Limits Phage
    Epidemics in Bacterial Populations</i>. Dryad, 2018, doi:<a href="https://doi.org/10.5061/dryad.42n44">10.5061/dryad.42n44</a>.'
  short: P. Payne, L. Geyrhofer, N.H. Barton, J.P. Bollback, (2018).
date_created: 2021-08-09T13:10:02Z
date_published: 2018-03-12T00:00:00Z
date_updated: 2023-09-11T12:49:17Z
day: '12'
department:
- _id: NiBa
- _id: JoBo
doi: 10.5061/dryad.42n44
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5061/dryad.42n44
month: '03'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
  record:
  - id: '423'
    relation: used_in_publication
    status: public
status: public
title: 'Data from: CRISPR-based herd immunity limits phage epidemics in bacterial
  populations'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2018'
...
---
_id: '9841'
abstract:
- lang: eng
  text: Around 150 million years ago, eusocial termites evolved from within the cockroaches,
    50 million years before eusocial Hymenoptera, such as bees and ants, appeared.
    Here, we report the 2-Gb genome of the German cockroach, Blattella germanica,
    and the 1.3-Gb genome of the drywood termite Cryptotermes secundus. We show evolutionary
    signatures of termite eusociality by comparing the genomes and transcriptomes
    of three termites and the cockroach against the background of 16 other eusocial
    and non-eusocial insects. Dramatic adaptive changes in genes underlying the production
    and perception of pheromones confirm the importance of chemical communication
    in the termites. These are accompanied by major changes in gene regulation and
    the molecular evolution of caste determination. Many of these results parallel
    molecular mechanisms of eusocial evolution in Hymenoptera. However, the specific
    solutions are remarkably different, thus revealing a striking case of convergence
    in one of the major evolutionary transitions in biological complexity.
article_processing_charge: No
author:
- first_name: Mark C.
  full_name: Harrison, Mark C.
  last_name: Harrison
- first_name: Evelien
  full_name: Jongepier, Evelien
  last_name: Jongepier
- first_name: Hugh M.
  full_name: Robertson, Hugh M.
  last_name: Robertson
- first_name: Nicolas
  full_name: Arning, Nicolas
  last_name: Arning
- first_name: Tristan
  full_name: Bitard-Feildel, Tristan
  last_name: Bitard-Feildel
- first_name: Hsu
  full_name: Chao, Hsu
  last_name: Chao
- first_name: Christopher P.
  full_name: Childers, Christopher P.
  last_name: Childers
- first_name: Huyen
  full_name: Dinh, Huyen
  last_name: Dinh
- first_name: Harshavardhan
  full_name: Doddapaneni, Harshavardhan
  last_name: Doddapaneni
- first_name: Shannon
  full_name: Dugan, Shannon
  last_name: Dugan
- first_name: Johannes
  full_name: Gowin, Johannes
  last_name: Gowin
- first_name: Carolin
  full_name: Greiner, Carolin
  last_name: Greiner
- first_name: Yi
  full_name: Han, Yi
  last_name: Han
- first_name: Haofu
  full_name: Hu, Haofu
  last_name: Hu
- first_name: Daniel S. T.
  full_name: Hughes, Daniel S. T.
  last_name: Hughes
- first_name: Ann K
  full_name: Huylmans, Ann K
  id: 4C0A3874-F248-11E8-B48F-1D18A9856A87
  last_name: Huylmans
  orcid: 0000-0001-8871-4961
- first_name: Carsten
  full_name: Kemena, Carsten
  last_name: Kemena
- first_name: Lukas P. M.
  full_name: Kremer, Lukas P. M.
  last_name: Kremer
- first_name: Sandra L.
  full_name: Lee, Sandra L.
  last_name: Lee
- first_name: Alberto
  full_name: Lopez-Ezquerra, Alberto
  last_name: Lopez-Ezquerra
- first_name: Ludovic
  full_name: Mallet, Ludovic
  last_name: Mallet
- first_name: Jose M.
  full_name: Monroy-Kuhn, Jose M.
  last_name: Monroy-Kuhn
- first_name: Annabell
  full_name: Moser, Annabell
  last_name: Moser
- first_name: Shwetha C.
  full_name: Murali, Shwetha C.
  last_name: Murali
- first_name: Donna M.
  full_name: Muzny, Donna M.
  last_name: Muzny
- first_name: Saria
  full_name: Otani, Saria
  last_name: Otani
- first_name: Maria-Dolors
  full_name: Piulachs, Maria-Dolors
  last_name: Piulachs
- first_name: Monica
  full_name: Poelchau, Monica
  last_name: Poelchau
- first_name: Jiaxin
  full_name: Qu, Jiaxin
  last_name: Qu
- first_name: Florentine
  full_name: Schaub, Florentine
  last_name: Schaub
- first_name: Ayako
  full_name: Wada-Katsumata, Ayako
  last_name: Wada-Katsumata
- first_name: Kim C.
  full_name: Worley, Kim C.
  last_name: Worley
- first_name: Qiaolin
  full_name: Xie, Qiaolin
  last_name: Xie
- first_name: Guillem
  full_name: Ylla, Guillem
  last_name: Ylla
- first_name: Michael
  full_name: Poulsen, Michael
  last_name: Poulsen
- first_name: Richard A.
  full_name: Gibbs, Richard A.
  last_name: Gibbs
- first_name: Coby
  full_name: Schal, Coby
  last_name: Schal
- first_name: Stephen
  full_name: Richards, Stephen
  last_name: Richards
- first_name: Xavier
  full_name: Belles, Xavier
  last_name: Belles
- first_name: Judith
  full_name: Korb, Judith
  last_name: Korb
- first_name: Erich
  full_name: Bornberg-Bauer, Erich
  last_name: Bornberg-Bauer
citation:
  ama: 'Harrison MC, Jongepier E, Robertson HM, et al. Data from: Hemimetabolous genomes
    reveal molecular basis of termite eusociality. 2018. doi:<a href="https://doi.org/10.5061/dryad.51d4r">10.5061/dryad.51d4r</a>'
  apa: 'Harrison, M. C., Jongepier, E., Robertson, H. M., Arning, N., Bitard-Feildel,
    T., Chao, H., … Bornberg-Bauer, E. (2018). Data from: Hemimetabolous genomes reveal
    molecular basis of termite eusociality. Dryad. <a href="https://doi.org/10.5061/dryad.51d4r">https://doi.org/10.5061/dryad.51d4r</a>'
  chicago: 'Harrison, Mark C., Evelien Jongepier, Hugh M. Robertson, Nicolas Arning,
    Tristan Bitard-Feildel, Hsu Chao, Christopher P. Childers, et al. “Data from:
    Hemimetabolous Genomes Reveal Molecular Basis of Termite Eusociality.” Dryad,
    2018. <a href="https://doi.org/10.5061/dryad.51d4r">https://doi.org/10.5061/dryad.51d4r</a>.'
  ieee: 'M. C. Harrison <i>et al.</i>, “Data from: Hemimetabolous genomes reveal molecular
    basis of termite eusociality.” Dryad, 2018.'
  ista: 'Harrison MC, Jongepier E, Robertson HM, Arning N, Bitard-Feildel T, Chao
    H, Childers CP, Dinh H, Doddapaneni H, Dugan S, Gowin J, Greiner C, Han Y, Hu
    H, Hughes DST, Huylmans AK, Kemena C, Kremer LPM, Lee SL, Lopez-Ezquerra A, Mallet
    L, Monroy-Kuhn JM, Moser A, Murali SC, Muzny DM, Otani S, Piulachs M-D, Poelchau
    M, Qu J, Schaub F, Wada-Katsumata A, Worley KC, Xie Q, Ylla G, Poulsen M, Gibbs
    RA, Schal C, Richards S, Belles X, Korb J, Bornberg-Bauer E. 2018. Data from:
    Hemimetabolous genomes reveal molecular basis of termite eusociality, Dryad, <a
    href="https://doi.org/10.5061/dryad.51d4r">10.5061/dryad.51d4r</a>.'
  mla: 'Harrison, Mark C., et al. <i>Data from: Hemimetabolous Genomes Reveal Molecular
    Basis of Termite Eusociality</i>. Dryad, 2018, doi:<a href="https://doi.org/10.5061/dryad.51d4r">10.5061/dryad.51d4r</a>.'
  short: M.C. Harrison, E. Jongepier, H.M. Robertson, N. Arning, T. Bitard-Feildel,
    H. Chao, C.P. Childers, H. Dinh, H. Doddapaneni, S. Dugan, J. Gowin, C. Greiner,
    Y. Han, H. Hu, D.S.T. Hughes, A.K. Huylmans, C. Kemena, L.P.M. Kremer, S.L. Lee,
    A. Lopez-Ezquerra, L. Mallet, J.M. Monroy-Kuhn, A. Moser, S.C. Murali, D.M. Muzny,
    S. Otani, M.-D. Piulachs, M. Poelchau, J. Qu, F. Schaub, A. Wada-Katsumata, K.C.
    Worley, Q. Xie, G. Ylla, M. Poulsen, R.A. Gibbs, C. Schal, S. Richards, X. Belles,
    J. Korb, E. Bornberg-Bauer, (2018).
date_created: 2021-08-09T13:13:48Z
date_published: 2018-12-12T00:00:00Z
date_updated: 2023-09-11T14:10:56Z
day: '12'
department:
- _id: BeVi
doi: 10.5061/dryad.51d4r
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5061/dryad.51d4r
month: '12'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
  record:
  - id: '448'
    relation: used_in_publication
    status: public
status: public
title: 'Data from: Hemimetabolous genomes reveal molecular basis of termite eusociality'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2018'
...
---
_id: '9915'
abstract:
- lang: eng
  text: 'The evolution of assortative mating is a key part of the speciation process.
    Stronger assortment, or greater divergence in mating traits, between species pairs
    with overlapping ranges is commonly observed, but possible causes of this pattern
    of reproductive character displacement are difficult to distinguish. We use a
    multidisciplinary approach to provide a rare example where it is possible to distinguish
    among hypotheses concerning the evolution of reproductive character displacement.
    We build on an earlier comparative analysis that illustrated a strong pattern
    of greater divergence in penis form between pairs of sister species with overlapping
    ranges than between allopatric sister-species pairs, in a large clade of marine
    gastropods (Littorinidae). We investigate both assortative mating and divergence
    in male genitalia in one of the sister-species pairs, discriminating among three
    contrasting processes each of which can generate a pattern of reproductive character
    displacement: reinforcement, reproductive interference and the Templeton effect.
    We demonstrate reproductive character displacement in assortative mating, but
    not in genital form between this pair of sister species and use demographic models
    to distinguish among the different processes. Our results support a model with
    no gene flow since secondary contact and thus favor reproductive interference
    as the cause of reproductive character displacement for mate choice, rather than
    reinforcement. High gene flow within species argues against the Templeton effect.
    Secondary contact appears to have had little impact on genital divergence.'
acknowledgement: The authors express a special thanks to Dr Richard Willan at the
  Museum and Art Gallery of the Northern Territory for guidance and support in the
  field, and to Carole Smadja for reading and commenting on the manuscript. The authors
  thank the Government of Western Australia Department of Parks and Wildlife (license
  no. 009254) and Fishery Research Division (exemption no. 2262) for assistance with
  permits. Khalid Belkhir modified the coalescent sampler msnsam for the specific
  needs of this project and Martin Hirsch helped to set up the ABC pipeline and to
  modify the summary statistic calculator mscalc. The authors are grateful to the
  Crafoord Foundation for supporting this project. R.K.B., A.M.W., and L.D. were supported
  by grants from the Natural Environment Research Council, R.K.B. and A.M.W. were
  also supported by the European Research Council and R.K.B. and L.D. by the Leverhulme
  Trust. M.M.R. was supported by Consejo Nacional de Ciencia y Tecnología and Secretaría
  de Educación Pública, Mexico. G.B. was supported by the Centre for Animal Movement
  Research (CAnMove) financed by a Linnaeus grant (No. 349-2007-8690) from the Swedish
  Research Council and Lund University.
article_processing_charge: Yes
article_type: letter_note
author:
- first_name: Johan
  full_name: Hollander, Johan
  last_name: Hollander
- first_name: Mauricio
  full_name: Montaño-Rendón, Mauricio
  last_name: Montaño-Rendón
- first_name: Giuseppe
  full_name: Bianco, Giuseppe
  last_name: Bianco
- first_name: Xi
  full_name: Yang, Xi
  last_name: Yang
- first_name: Anja M
  full_name: Westram, Anja M
  id: 3C147470-F248-11E8-B48F-1D18A9856A87
  last_name: Westram
  orcid: 0000-0003-1050-4969
- first_name: Ludovic
  full_name: Duvaux, Ludovic
  last_name: Duvaux
- first_name: David G.
  full_name: Reid, David G.
  last_name: Reid
- first_name: Roger K.
  full_name: Butlin, Roger K.
  last_name: Butlin
citation:
  ama: Hollander J, Montaño-Rendón M, Bianco G, et al. Are assortative mating and
    genital divergence driven by reinforcement? <i>Evolution Letters</i>. 2018;2(6):557-566.
    doi:<a href="https://doi.org/10.1002/evl3.85">10.1002/evl3.85</a>
  apa: Hollander, J., Montaño-Rendón, M., Bianco, G., Yang, X., Westram, A. M., Duvaux,
    L., … Butlin, R. K. (2018). Are assortative mating and genital divergence driven
    by reinforcement? <i>Evolution Letters</i>. Wiley. <a href="https://doi.org/10.1002/evl3.85">https://doi.org/10.1002/evl3.85</a>
  chicago: Hollander, Johan, Mauricio Montaño-Rendón, Giuseppe Bianco, Xi Yang, Anja
    M Westram, Ludovic Duvaux, David G. Reid, and Roger K. Butlin. “Are Assortative
    Mating and Genital Divergence Driven by Reinforcement?” <i>Evolution Letters</i>.
    Wiley, 2018. <a href="https://doi.org/10.1002/evl3.85">https://doi.org/10.1002/evl3.85</a>.
  ieee: J. Hollander <i>et al.</i>, “Are assortative mating and genital divergence
    driven by reinforcement?,” <i>Evolution Letters</i>, vol. 2, no. 6. Wiley, pp.
    557–566, 2018.
  ista: Hollander J, Montaño-Rendón M, Bianco G, Yang X, Westram AM, Duvaux L, Reid
    DG, Butlin RK. 2018. Are assortative mating and genital divergence driven by reinforcement?
    Evolution Letters. 2(6), 557–566.
  mla: Hollander, Johan, et al. “Are Assortative Mating and Genital Divergence Driven
    by Reinforcement?” <i>Evolution Letters</i>, vol. 2, no. 6, Wiley, 2018, pp. 557–66,
    doi:<a href="https://doi.org/10.1002/evl3.85">10.1002/evl3.85</a>.
  short: J. Hollander, M. Montaño-Rendón, G. Bianco, X. Yang, A.M. Westram, L. Duvaux,
    D.G. Reid, R.K. Butlin, Evolution Letters 2 (2018) 557–566.
date_created: 2021-08-16T07:30:00Z
date_published: 2018-12-13T00:00:00Z
date_updated: 2023-09-19T15:08:53Z
day: '13'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.1002/evl3.85
external_id:
  isi:
  - '000452990000002'
  pmid:
  - '30564439'
file:
- access_level: open_access
  checksum: 997a78ac41c809975ca69cbdea441f88
  content_type: application/pdf
  creator: asandaue
  date_created: 2021-08-16T07:37:28Z
  date_updated: 2021-08-16T07:37:28Z
  file_id: '9916'
  file_name: 2018_EvolutionLetters_Hollander.pdf
  file_size: 584606
  relation: main_file
  success: 1
file_date_updated: 2021-08-16T07:37:28Z
has_accepted_license: '1'
intvolume: '         2'
isi: 1
issue: '6'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '12'
oa: 1
oa_version: Published Version
page: 557-566
pmid: 1
publication: Evolution Letters
publication_identifier:
  eissn:
  - 2056-3744
  issn:
  - ' 2056-3744'
publication_status: published
publisher: Wiley
quality_controlled: '1'
related_material:
  record:
  - id: '9929'
    relation: research_data
    status: public
status: public
title: Are assortative mating and genital divergence driven by reinforcement?
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 2
year: '2018'
...
---
_id: '9917'
abstract:
- lang: eng
  text: Adaptive divergence and speciation may happen despite opposition by gene flow.
    Identifying the genomic basis underlying divergence with gene flow is a major
    task in evolutionary genomics. Most approaches (e.g., outlier scans) focus on
    genomic regions of high differentiation. However, not all genomic architectures
    potentially underlying divergence are expected to show extreme differentiation.
    Here, we develop an approach that combines hybrid zone analysis (i.e., focuses
    on spatial patterns of allele frequency change) with system-specific simulations
    to identify loci inconsistent with neutral evolution. We apply this to a genome-wide
    SNP set from an ideally suited study organism, the intertidal snail Littorina
    saxatilis, which shows primary divergence between ecotypes associated with different
    shore habitats. We detect many SNPs with clinal patterns, most of which are consistent
    with neutrality. Among non-neutral SNPs, most are located within three large putative
    inversions differentiating ecotypes. Many non-neutral SNPs show relatively low
    levels of differentiation. We discuss potential reasons for this pattern, including
    loose linkage to selected variants, polygenic adaptation and a component of balancing
    selection within populations (which may be expected for inversions). Our work
    is in line with theory predicting a role for inversions in divergence, and emphasizes
    that genomic regions contributing to divergence may not always be accessible with
    methods purely based on allele frequency differences. These conclusions call for
    approaches that take spatial patterns of allele frequency change into account
    in other systems.
acknowledgement: We are very grateful to people who helped with fieldwork, snail processing,
  and DNA extractions, particularly Laura Brettell, Mårten Duvetorp, Juan Galindo,
  Anne-Lise Liabot and Irena Senčić. We would also like to thank Magnus Alm Rosenblad
  and Mats Töpel for their contribution to assembling the Littorina saxatilis genome,
  Carl André, Pasi Rastas, and Romain Villoutreix for discussion, and two anonymous
  reviewers for their helpful comments on the manuscript. We are grateful to RapidGenomics
  for library preparation and sequencing. We thank the Natural Environment Research
  Council, the European Research Council and the Swedish Research Councils VR and
  Formas (Linnaeus grant to the Centre for Marine Evolutionary Biology and Tage Erlander
  Guest Professorship) for funding. P.C. was funded by the University of Sheffield
  Vice-chancellor's India scholarship. R.F. is funded by the European Union's Horizon
  2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement
  no. 706376. M. Raf. was supported by the Adlerbert Research Foundation.
article_processing_charge: Yes
article_type: letter_note
author:
- first_name: Anja M
  full_name: Westram, Anja M
  id: 3C147470-F248-11E8-B48F-1D18A9856A87
  last_name: Westram
  orcid: 0000-0003-1050-4969
- first_name: Marina
  full_name: Rafajlović, Marina
  last_name: Rafajlović
- first_name: Pragya
  full_name: Chaube, Pragya
  last_name: Chaube
- first_name: Rui
  full_name: Faria, Rui
  last_name: Faria
- first_name: Tomas
  full_name: Larsson, Tomas
  last_name: Larsson
- first_name: Marina
  full_name: Panova, Marina
  last_name: Panova
- first_name: Mark
  full_name: Ravinet, Mark
  last_name: Ravinet
- first_name: Anders
  full_name: Blomberg, Anders
  last_name: Blomberg
- first_name: Bernhard
  full_name: Mehlig, Bernhard
  last_name: Mehlig
- first_name: Kerstin
  full_name: Johannesson, Kerstin
  last_name: Johannesson
- first_name: Roger
  full_name: Butlin, Roger
  last_name: Butlin
citation:
  ama: 'Westram AM, Rafajlović M, Chaube P, et al. Clines on the seashore: The genomic
    architecture underlying rapid divergence in the face of gene flow. <i>Evolution
    Letters</i>. 2018;2(4):297-309. doi:<a href="https://doi.org/10.1002/evl3.74">10.1002/evl3.74</a>'
  apa: 'Westram, A. M., Rafajlović, M., Chaube, P., Faria, R., Larsson, T., Panova,
    M., … Butlin, R. (2018). Clines on the seashore: The genomic architecture underlying
    rapid divergence in the face of gene flow. <i>Evolution Letters</i>. Wiley. <a
    href="https://doi.org/10.1002/evl3.74">https://doi.org/10.1002/evl3.74</a>'
  chicago: 'Westram, Anja M, Marina Rafajlović, Pragya Chaube, Rui Faria, Tomas Larsson,
    Marina Panova, Mark Ravinet, et al. “Clines on the Seashore: The Genomic Architecture
    Underlying Rapid Divergence in the Face of Gene Flow.” <i>Evolution Letters</i>.
    Wiley, 2018. <a href="https://doi.org/10.1002/evl3.74">https://doi.org/10.1002/evl3.74</a>.'
  ieee: 'A. M. Westram <i>et al.</i>, “Clines on the seashore: The genomic architecture
    underlying rapid divergence in the face of gene flow,” <i>Evolution Letters</i>,
    vol. 2, no. 4. Wiley, pp. 297–309, 2018.'
  ista: 'Westram AM, Rafajlović M, Chaube P, Faria R, Larsson T, Panova M, Ravinet
    M, Blomberg A, Mehlig B, Johannesson K, Butlin R. 2018. Clines on the seashore:
    The genomic architecture underlying rapid divergence in the face of gene flow.
    Evolution Letters. 2(4), 297–309.'
  mla: 'Westram, Anja M., et al. “Clines on the Seashore: The Genomic Architecture
    Underlying Rapid Divergence in the Face of Gene Flow.” <i>Evolution Letters</i>,
    vol. 2, no. 4, Wiley, 2018, pp. 297–309, doi:<a href="https://doi.org/10.1002/evl3.74">10.1002/evl3.74</a>.'
  short: A.M. Westram, M. Rafajlović, P. Chaube, R. Faria, T. Larsson, M. Panova,
    M. Ravinet, A. Blomberg, B. Mehlig, K. Johannesson, R. Butlin, Evolution Letters
    2 (2018) 297–309.
date_created: 2021-08-16T07:45:38Z
date_published: 2018-08-20T00:00:00Z
date_updated: 2023-09-19T15:08:25Z
day: '20'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.1002/evl3.74
external_id:
  isi:
  - '000446774400004'
  pmid:
  - '30283683'
file:
- access_level: open_access
  checksum: 8524e72507d521416be3f8ccfcd5e3f5
  content_type: application/pdf
  creator: asandaue
  date_created: 2021-08-16T07:48:03Z
  date_updated: 2021-08-16T07:48:03Z
  file_id: '9918'
  file_name: 2018_EvolutionLetters_Westram.pdf
  file_size: 764299
  relation: main_file
  success: 1
file_date_updated: 2021-08-16T07:48:03Z
has_accepted_license: '1'
intvolume: '         2'
isi: 1
issue: '4'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: 297-309
pmid: 1
publication: Evolution Letters
publication_identifier:
  eissn:
  - 2056-3744
  issn:
  - 2056-3744
publication_status: published
publisher: Wiley
quality_controlled: '1'
related_material:
  record:
  - id: '9930'
    relation: research_data
    status: public
status: public
title: 'Clines on the seashore: The genomic architecture underlying rapid divergence
  in the face of gene flow'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 2
year: '2018'
...
---
_id: '9929'
abstract:
- lang: eng
  text: 'The evolution of assortative mating is a key part of the speciation process.
    Stronger assortment, or greater divergence in mating traits, between species pairs
    with overlapping ranges is commonly observed, but possible causes of this pattern
    of reproductive character displacement are difficult to distinguish. We use a
    multidisciplinary approach to provide a rare example where it is possible to distinguish
    among hypotheses concerning the evolution of reproductive character displacement.
    We build on an earlier comparative analysis that illustrated a strong pattern
    of greater divergence in penis form between pairs of sister species with overlapping
    ranges than between allopatric sister-species pairs, in a large clade of marine
    gastropods (Littorinidae). We investigate both assortative mating and divergence
    in male genitalia in one of the sister-species pairs, discriminating among three
    contrasting processes each of which can generate a pattern of reproductive character
    displacement: reinforcement, reproductive interference and the Templeton effect.
    We demonstrate reproductive character displacement in assortative mating, but
    not in genital form between this pair of sister species and use demographic models
    to distinguish among the different processes. Our results support a model with
    no gene flow since secondary contact and thus favour reproductive interference
    as the cause of reproductive character displacement for mate choice, rather than
    reinforcement. High gene flow within species argues against the Templeton effect.
    Secondary contact appears to have had little impact on genital divergence.'
article_processing_charge: No
author:
- first_name: Johan
  full_name: Hollander, Johan
  last_name: Hollander
- first_name: Mauricio
  full_name: Montaño-Rendón, Mauricio
  last_name: Montaño-Rendón
- first_name: Giuseppe
  full_name: Bianco, Giuseppe
  last_name: Bianco
- first_name: Xi
  full_name: Yang, Xi
  last_name: Yang
- first_name: Anja M
  full_name: Westram, Anja M
  id: 3C147470-F248-11E8-B48F-1D18A9856A87
  last_name: Westram
  orcid: 0000-0003-1050-4969
- first_name: Ludovic
  full_name: Duvaux, Ludovic
  last_name: Duvaux
- first_name: David G.
  full_name: Reid, David G.
  last_name: Reid
- first_name: Roger K.
  full_name: Butlin, Roger K.
  last_name: Butlin
citation:
  ama: 'Hollander J, Montaño-Rendón M, Bianco G, et al. Data from: Are assortative
    mating and genital divergence driven by reinforcement? 2018. doi:<a href="https://doi.org/10.5061/dryad.51sd2p5">10.5061/dryad.51sd2p5</a>'
  apa: 'Hollander, J., Montaño-Rendón, M., Bianco, G., Yang, X., Westram, A. M., Duvaux,
    L., … Butlin, R. K. (2018). Data from: Are assortative mating and genital divergence
    driven by reinforcement? Dryad. <a href="https://doi.org/10.5061/dryad.51sd2p5">https://doi.org/10.5061/dryad.51sd2p5</a>'
  chicago: 'Hollander, Johan, Mauricio Montaño-Rendón, Giuseppe Bianco, Xi Yang, Anja
    M Westram, Ludovic Duvaux, David G. Reid, and Roger K. Butlin. “Data from: Are
    Assortative Mating and Genital Divergence Driven by Reinforcement?” Dryad, 2018.
    <a href="https://doi.org/10.5061/dryad.51sd2p5">https://doi.org/10.5061/dryad.51sd2p5</a>.'
  ieee: 'J. Hollander <i>et al.</i>, “Data from: Are assortative mating and genital
    divergence driven by reinforcement?” Dryad, 2018.'
  ista: 'Hollander J, Montaño-Rendón M, Bianco G, Yang X, Westram AM, Duvaux L, Reid
    DG, Butlin RK. 2018. Data from: Are assortative mating and genital divergence
    driven by reinforcement?, Dryad, <a href="https://doi.org/10.5061/dryad.51sd2p5">10.5061/dryad.51sd2p5</a>.'
  mla: 'Hollander, Johan, et al. <i>Data from: Are Assortative Mating and Genital
    Divergence Driven by Reinforcement?</i> Dryad, 2018, doi:<a href="https://doi.org/10.5061/dryad.51sd2p5">10.5061/dryad.51sd2p5</a>.'
  short: J. Hollander, M. Montaño-Rendón, G. Bianco, X. Yang, A.M. Westram, L. Duvaux,
    D.G. Reid, R.K. Butlin, (2018).
date_created: 2021-08-17T08:51:06Z
date_published: 2018-10-17T00:00:00Z
date_updated: 2023-09-19T15:08:53Z
day: '17'
department:
- _id: BeVi
doi: 10.5061/dryad.51sd2p5
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5061/dryad.51sd2p5
month: '10'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
  record:
  - id: '9915'
    relation: used_in_publication
    status: public
status: public
title: 'Data from: Are assortative mating and genital divergence driven by reinforcement?'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2018'
...
---
_id: '9930'
abstract:
- lang: eng
  text: Adaptive divergence and speciation may happen despite opposition by gene flow.
    Identifying the genomic basis underlying divergence with gene flow is a major
    task in evolutionary genomics. Most approaches (e.g. outlier scans) focus on genomic
    regions of high differentiation. However, not all genomic architectures potentially
    underlying divergence are expected to show extreme differentiation. Here, we develop
    an approach that combines hybrid zone analysis (i.e. focuses on spatial patterns
    of allele frequency change) with system-specific simulations to identify loci
    inconsistent with neutral evolution. We apply this to a genome-wide SNP set from
    an ideally-suited study organism, the intertidal snail Littorina saxatilis, which
    shows primary divergence between ecotypes associated with different shore habitats.
    We detect many SNPs with clinal patterns, most of which are consistent with neutrality.
    Among non-neutral SNPs, most are located within three large putative inversions
    differentiating ecotypes. Many non-neutral SNPs show relatively low levels of
    differentiation. We discuss potential reasons for this pattern, including loose
    linkage to selected variants, polygenic adaptation and a component of balancing
    selection within populations (which may be expected for inversions). Our work
    is in line with theory predicting a role for inversions in divergence, and emphasises
    that genomic regions contributing to divergence may not always be accessible with
    methods purely based on allele frequency differences. These conclusions call for
    approaches that take spatial patterns of allele frequency change into account
    in other systems.
article_processing_charge: No
author:
- first_name: Anja M
  full_name: Westram, Anja M
  id: 3C147470-F248-11E8-B48F-1D18A9856A87
  last_name: Westram
  orcid: 0000-0003-1050-4969
- first_name: Marina
  full_name: Rafajlović, Marina
  last_name: Rafajlović
- first_name: Pragya
  full_name: Chaube, Pragya
  last_name: Chaube
- first_name: Rui
  full_name: Faria, Rui
  last_name: Faria
- first_name: Tomas
  full_name: Larsson, Tomas
  last_name: Larsson
- first_name: Marina
  full_name: Panova, Marina
  last_name: Panova
- first_name: Mark
  full_name: Ravinet, Mark
  last_name: Ravinet
- first_name: Anders
  full_name: Blomberg, Anders
  last_name: Blomberg
- first_name: Bernhard
  full_name: Mehlig, Bernhard
  last_name: Mehlig
- first_name: Kerstin
  full_name: Johannesson, Kerstin
  last_name: Johannesson
- first_name: Roger
  full_name: Butlin, Roger
  last_name: Butlin
citation:
  ama: 'Westram AM, Rafajlović M, Chaube P, et al. Data from: Clines on the seashore:
    the genomic architecture underlying rapid divergence in the face of gene flow.
    2018. doi:<a href="https://doi.org/10.5061/dryad.bp25b65">10.5061/dryad.bp25b65</a>'
  apa: 'Westram, A. M., Rafajlović, M., Chaube, P., Faria, R., Larsson, T., Panova,
    M., … Butlin, R. (2018). Data from: Clines on the seashore: the genomic architecture
    underlying rapid divergence in the face of gene flow. Dryad. <a href="https://doi.org/10.5061/dryad.bp25b65">https://doi.org/10.5061/dryad.bp25b65</a>'
  chicago: 'Westram, Anja M, Marina Rafajlović, Pragya Chaube, Rui Faria, Tomas Larsson,
    Marina Panova, Mark Ravinet, et al. “Data from: Clines on the Seashore: The Genomic
    Architecture Underlying Rapid Divergence in the Face of Gene Flow.” Dryad, 2018.
    <a href="https://doi.org/10.5061/dryad.bp25b65">https://doi.org/10.5061/dryad.bp25b65</a>.'
  ieee: 'A. M. Westram <i>et al.</i>, “Data from: Clines on the seashore: the genomic
    architecture underlying rapid divergence in the face of gene flow.” Dryad, 2018.'
  ista: 'Westram AM, Rafajlović M, Chaube P, Faria R, Larsson T, Panova M, Ravinet
    M, Blomberg A, Mehlig B, Johannesson K, Butlin R. 2018. Data from: Clines on the
    seashore: the genomic architecture underlying rapid divergence in the face of
    gene flow, Dryad, <a href="https://doi.org/10.5061/dryad.bp25b65">10.5061/dryad.bp25b65</a>.'
  mla: 'Westram, Anja M., et al. <i>Data from: Clines on the Seashore: The Genomic
    Architecture Underlying Rapid Divergence in the Face of Gene Flow</i>. Dryad,
    2018, doi:<a href="https://doi.org/10.5061/dryad.bp25b65">10.5061/dryad.bp25b65</a>.'
  short: A.M. Westram, M. Rafajlović, P. Chaube, R. Faria, T. Larsson, M. Panova,
    M. Ravinet, A. Blomberg, B. Mehlig, K. Johannesson, R. Butlin, (2018).
date_created: 2021-08-17T08:58:47Z
date_published: 2018-07-23T00:00:00Z
date_updated: 2023-09-19T15:08:24Z
day: '23'
department:
- _id: BeVi
doi: 10.5061/dryad.bp25b65
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5061/dryad.bp25b65
month: '07'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
  record:
  - id: '9917'
    relation: used_in_publication
    status: public
status: public
title: 'Data from: Clines on the seashore: the genomic architecture underlying rapid
  divergence in the face of gene flow'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2018'
...
---
_id: '34'
abstract:
- lang: eng
  text: Partially observable Markov decision processes (POMDPs) are widely used in
    probabilistic planning problems in which an agent interacts with an environment
    using noisy and imprecise sensors. We study a setting in which the sensors are
    only partially defined and the goal is to synthesize “weakest” additional sensors,
    such that in the resulting POMDP, there is a small-memory policy for the agent
    that almost-surely (with probability 1) satisfies a reachability objective. We
    show that the problem is NP-complete, and present a symbolic algorithm by encoding
    the problem into SAT instances. We illustrate trade-offs between the amount of
    memory of the policy and the number of additional sensors on a simple example.
    We have implemented our approach and consider three classical POMDP examples from
    the literature, and show that in all the examples the number of sensors can be
    significantly decreased (as compared to the existing solutions in the literature)
    without increasing the complexity of the policies.
alternative_title:
- ICAPS
article_processing_charge: No
arxiv: 1
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Martin
  full_name: Chemlík, Martin
  last_name: Chemlík
- first_name: Ufuk
  full_name: Topcu, Ufuk
  last_name: Topcu
citation:
  ama: 'Chatterjee K, Chemlík M, Topcu U. Sensor synthesis for POMDPs with reachability
    objectives. In: Vol 2018. AAAI Press; 2018:47-55.'
  apa: 'Chatterjee, K., Chemlík, M., &#38; Topcu, U. (2018). Sensor synthesis for
    POMDPs with reachability objectives (Vol. 2018, pp. 47–55). Presented at the ICAPS:
    International Conference on Automated Planning and Scheduling, Delft, Netherlands:
    AAAI Press.'
  chicago: Chatterjee, Krishnendu, Martin Chemlík, and Ufuk Topcu. “Sensor Synthesis
    for POMDPs with Reachability Objectives,” 2018:47–55. AAAI Press, 2018.
  ieee: 'K. Chatterjee, M. Chemlík, and U. Topcu, “Sensor synthesis for POMDPs with
    reachability objectives,” presented at the ICAPS: International Conference on
    Automated Planning and Scheduling, Delft, Netherlands, 2018, vol. 2018, pp. 47–55.'
  ista: 'Chatterjee K, Chemlík M, Topcu U. 2018. Sensor synthesis for POMDPs with
    reachability objectives. ICAPS: International Conference on Automated Planning
    and Scheduling, ICAPS, vol. 2018, 47–55.'
  mla: Chatterjee, Krishnendu, et al. <i>Sensor Synthesis for POMDPs with Reachability
    Objectives</i>. Vol. 2018, AAAI Press, 2018, pp. 47–55.
  short: K. Chatterjee, M. Chemlík, U. Topcu, in:, AAAI Press, 2018, pp. 47–55.
conference:
  end_date: 2018-06-29
  location: Delft, Netherlands
  name: 'ICAPS: International Conference on Automated Planning and Scheduling'
  start_date: 2018-06-24
date_created: 2018-12-11T11:44:16Z
date_published: 2018-06-01T00:00:00Z
date_updated: 2023-09-19T14:44:14Z
day: '01'
department:
- _id: KrCh
ec_funded: 1
external_id:
  arxiv:
  - '1710.00675'
  isi:
  - '000492986200006'
intvolume: '      2018'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1710.00675
month: '06'
oa: 1
oa_version: Preprint
page: 47 - 55
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P 23499-N23
  name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '279307'
  name: 'Quantitative Graph Games: Theory and Applications'
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S 11407_N23
  name: Rigorous Systems Engineering
- _id: 2587B514-B435-11E9-9278-68D0E5697425
  name: Microsoft Research Faculty Fellowship
publication_status: published
publisher: AAAI Press
publist_id: '8021'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Sensor synthesis for POMDPs with reachability objectives
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 2018
year: '2018'
...
---
_id: '35'
abstract:
- lang: eng
  text: 'We consider planning problems for graphs, Markov decision processes (MDPs),
    and games on graphs. While graphs represent the most basic planning model, MDPs
    represent interaction with nature and games on graphs represent interaction with
    an adversarial environment. We consider two planning problems where there are
    k different target sets, and the problems are as follows: (a) the coverage problem
    asks whether there is a plan for each individual target set; and (b) the sequential
    target reachability problem asks whether the targets can be reached in sequence.
    For the coverage problem, we present a linear-time algorithm for graphs, and quadratic
    conditional lower bound for MDPs and games on graphs. For the sequential target
    problem, we present a linear-time algorithm for graphs, a sub-quadratic algorithm
    for MDPs, and a quadratic conditional lower bound for games on graphs. Our results
    with conditional lower bounds establish (i) model-separation results showing that
    for the coverage problem MDPs and games on graphs are harder than graphs and for
    the sequential reachability problem games on graphs are harder than MDPs and graphs;
    and (ii) objective-separation results showing that for MDPs the coverage problem
    is harder than the sequential target problem.'
article_processing_charge: No
arxiv: 1
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Wolfgang
  full_name: Dvorák, Wolfgang
  last_name: Dvorák
- first_name: Monika H
  full_name: Henzinger, Monika H
  id: 540c9bbd-f2de-11ec-812d-d04a5be85630
  last_name: Henzinger
  orcid: 0000-0002-5008-6530
- first_name: Alexander
  full_name: Svozil, Alexander
  last_name: Svozil
citation:
  ama: 'Chatterjee K, Dvorák W, Henzinger MH, Svozil A. Algorithms and conditional
    lower bounds for planning problems. In: <i>28th International Conference on Automated
    Planning and Scheduling </i>. AAAI Press; 2018.'
  apa: 'Chatterjee, K., Dvorák, W., Henzinger, M. H., &#38; Svozil, A. (2018). Algorithms
    and conditional lower bounds for planning problems. In <i>28th International Conference
    on Automated Planning and Scheduling </i>. Delft, Netherlands: AAAI Press.'
  chicago: Chatterjee, Krishnendu, Wolfgang Dvorák, Monika H Henzinger, and Alexander
    Svozil. “Algorithms and Conditional Lower Bounds for Planning Problems.” In <i>28th
    International Conference on Automated Planning and Scheduling </i>. AAAI Press,
    2018.
  ieee: K. Chatterjee, W. Dvorák, M. H. Henzinger, and A. Svozil, “Algorithms and
    conditional lower bounds for planning problems,” in <i>28th International Conference
    on Automated Planning and Scheduling </i>, Delft, Netherlands, 2018.
  ista: 'Chatterjee K, Dvorák W, Henzinger MH, Svozil A. 2018. Algorithms and conditional
    lower bounds for planning problems. 28th International Conference on Automated
    Planning and Scheduling . ICAPS: International Conference on Automated Planning
    and Scheduling.'
  mla: Chatterjee, Krishnendu, et al. “Algorithms and Conditional Lower Bounds for
    Planning Problems.” <i>28th International Conference on Automated Planning and
    Scheduling </i>, AAAI Press, 2018.
  short: K. Chatterjee, W. Dvorák, M.H. Henzinger, A. Svozil, in:, 28th International
    Conference on Automated Planning and Scheduling , AAAI Press, 2018.
conference:
  end_date: 2018-06-29
  location: Delft, Netherlands
  name: 'ICAPS: International Conference on Automated Planning and Scheduling'
  start_date: 2018-06-24
date_created: 2018-12-11T11:44:17Z
date_published: 2018-06-01T00:00:00Z
date_updated: 2023-09-26T10:41:41Z
day: '01'
department:
- _id: KrCh
ec_funded: 1
external_id:
  arxiv:
  - '1804.07031'
  isi:
  - '000492986200007'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1804.07031
month: '06'
oa: 1
oa_version: None
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S 11407_N23
  name: Rigorous Systems Engineering
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '279307'
  name: 'Quantitative Graph Games: Theory and Applications'
publication: '28th International Conference on Automated Planning and Scheduling '
publication_status: published
publisher: AAAI Press
publist_id: '8020'
quality_controlled: '1'
related_material:
  record:
  - id: '9293'
    relation: later_version
    status: public
scopus_import: '1'
status: public
title: Algorithms and conditional lower bounds for planning problems
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2018'
...
---
_id: '36'
abstract:
- lang: eng
  text: Wheat (Triticum ssp.) is one of the most important human food sources. However,
    this crop is very sensitive to temperature changes. Specifically, processes during
    wheat leaf, flower, and seed development and photosynthesis, which all contribute
    to the yield of this crop, are affected by high temperature. While this has to
    some extent been investigated on physiological, developmental, and molecular levels,
    very little is known about early signalling events associated with an increase
    in temperature. Phosphorylation-mediated signalling mechanisms, which are quick
    and dynamic, are associated with plant growth and development, also under abiotic
    stress conditions. Therefore, we probed the impact of a short-term and mild increase
    in temperature on the wheat leaf and spikelet phosphoproteome. In total, 3822
    (containing 5178 phosphosites) and 5581 phosphopeptides (containing 7023 phosphosites)
    were identified in leaf and spikelet samples, respectively. Following statistical
    analysis, the resulting data set provides the scientific community with a first
    large-scale plant phosphoproteome under the control of higher ambient temperature.
    This community resource on the high temperature-mediated wheat phosphoproteome
    will be valuable for future studies. Our analyses also revealed a core set of
    common proteins between leaf and spikelet, suggesting some level of conserved
    regulatory mechanisms. Furthermore, we observed temperature-regulated interconversion
    of phosphoforms, which probably impacts protein activity.
acknowledgement: TZ is supported by a grant from the Chinese Scholarship Council.
article_processing_charge: No
author:
- first_name: Lam
  full_name: Vu, Lam
  last_name: Vu
- first_name: Tingting
  full_name: Zhu, Tingting
  last_name: Zhu
- first_name: Inge
  full_name: Verstraeten, Inge
  id: 362BF7FE-F248-11E8-B48F-1D18A9856A87
  last_name: Verstraeten
  orcid: 0000-0001-7241-2328
- first_name: Brigitte
  full_name: Van De Cotte, Brigitte
  last_name: Van De Cotte
- first_name: Kris
  full_name: Gevaert, Kris
  last_name: Gevaert
- first_name: Ive
  full_name: De Smet, Ive
  last_name: De Smet
citation:
  ama: Vu L, Zhu T, Verstraeten I, Van De Cotte B, Gevaert K, De Smet I. Temperature-induced
    changes in the wheat phosphoproteome reveal temperature-regulated interconversion
    of phosphoforms. <i>Journal of Experimental Botany</i>. 2018;69(19):4609-4624.
    doi:<a href="https://doi.org/10.1093/jxb/ery204">10.1093/jxb/ery204</a>
  apa: Vu, L., Zhu, T., Verstraeten, I., Van De Cotte, B., Gevaert, K., &#38; De Smet,
    I. (2018). Temperature-induced changes in the wheat phosphoproteome reveal temperature-regulated
    interconversion of phosphoforms. <i>Journal of Experimental Botany</i>. Oxford
    University Press. <a href="https://doi.org/10.1093/jxb/ery204">https://doi.org/10.1093/jxb/ery204</a>
  chicago: Vu, Lam, Tingting Zhu, Inge Verstraeten, Brigitte Van De Cotte, Kris Gevaert,
    and Ive De Smet. “Temperature-Induced Changes in the Wheat Phosphoproteome Reveal
    Temperature-Regulated Interconversion of Phosphoforms.” <i>Journal of Experimental
    Botany</i>. Oxford University Press, 2018. <a href="https://doi.org/10.1093/jxb/ery204">https://doi.org/10.1093/jxb/ery204</a>.
  ieee: L. Vu, T. Zhu, I. Verstraeten, B. Van De Cotte, K. Gevaert, and I. De Smet,
    “Temperature-induced changes in the wheat phosphoproteome reveal temperature-regulated
    interconversion of phosphoforms,” <i>Journal of Experimental Botany</i>, vol.
    69, no. 19. Oxford University Press, pp. 4609–4624, 2018.
  ista: Vu L, Zhu T, Verstraeten I, Van De Cotte B, Gevaert K, De Smet I. 2018. Temperature-induced
    changes in the wheat phosphoproteome reveal temperature-regulated interconversion
    of phosphoforms. Journal of Experimental Botany. 69(19), 4609–4624.
  mla: Vu, Lam, et al. “Temperature-Induced Changes in the Wheat Phosphoproteome Reveal
    Temperature-Regulated Interconversion of Phosphoforms.” <i>Journal of Experimental
    Botany</i>, vol. 69, no. 19, Oxford University Press, 2018, pp. 4609–24, doi:<a
    href="https://doi.org/10.1093/jxb/ery204">10.1093/jxb/ery204</a>.
  short: L. Vu, T. Zhu, I. Verstraeten, B. Van De Cotte, K. Gevaert, I. De Smet, Journal
    of Experimental Botany 69 (2018) 4609–4624.
date_created: 2018-12-11T11:44:17Z
date_published: 2018-08-31T00:00:00Z
date_updated: 2023-09-19T10:00:46Z
day: '31'
ddc:
- '581'
department:
- _id: JiFr
doi: 10.1093/jxb/ery204
external_id:
  isi:
  - '000443568700010'
file:
- access_level: open_access
  checksum: 34cb0a1611588b75bd6f4913fb4e30f1
  content_type: application/pdf
  creator: dernst
  date_created: 2018-12-18T09:47:51Z
  date_updated: 2020-07-14T12:46:13Z
  file_id: '5741'
  file_name: 2018_JournalExperimBotany_Vu.pdf
  file_size: 3359316
  relation: main_file
file_date_updated: 2020-07-14T12:46:13Z
has_accepted_license: '1'
intvolume: '        69'
isi: 1
issue: '19'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: 4609 - 4624
publication: Journal of Experimental Botany
publication_status: published
publisher: Oxford University Press
publist_id: '8019'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Temperature-induced changes in the wheat phosphoproteome reveal temperature-regulated
  interconversion of phosphoforms
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 69
year: '2018'
...
---
_id: '37'
abstract:
- lang: eng
  text: Developmental processes are inherently dynamic and understanding them requires
    quantitative measurements of gene and protein expression levels in space and time.
    While live imaging is a powerful approach for obtaining such data, it is still
    a challenge to apply it over long periods of time to large tissues, such as the
    embryonic spinal cord in mouse and chick. Nevertheless, dynamics of gene expression
    and signaling activity patterns in this organ can be studied by collecting tissue
    sections at different developmental stages. In combination with immunohistochemistry,
    this allows for measuring the levels of multiple developmental regulators in a
    quantitative manner with high spatiotemporal resolution. The mean protein expression
    levels over time, as well as embryo-to-embryo variability can be analyzed. A key
    aspect of the approach is the ability to compare protein levels across different
    samples. This requires a number of considerations in sample preparation, imaging
    and data analysis. Here we present a protocol for obtaining time course data of
    dorsoventral expression patterns from mouse and chick neural tube in the first
    3 days of neural tube development. The described workflow starts from embryo dissection
    and ends with a processed dataset. Software scripts for data analysis are included.
    The protocol is adaptable and instructions that allow the user to modify different
    steps are provided. Thus, the procedure can be altered for analysis of time-lapse
    images and applied to systems other than the neural tube.
alternative_title:
- Methods in Molecular Biology
article_processing_charge: No
author:
- first_name: Marcin P
  full_name: Zagórski, Marcin P
  id: 343DA0DC-F248-11E8-B48F-1D18A9856A87
  last_name: Zagórski
  orcid: 0000-0001-7896-7762
- first_name: Anna
  full_name: Kicheva, Anna
  id: 3959A2A0-F248-11E8-B48F-1D18A9856A87
  last_name: Kicheva
  orcid: 0000-0003-4509-4998
citation:
  ama: 'Zagórski MP, Kicheva A. Measuring dorsoventral pattern and morphogen signaling
    profiles in the growing neural tube. In: <i>Morphogen Gradients </i>. Vol 1863.
    MIMB. Springer Nature; 2018:47-63. doi:<a href="https://doi.org/10.1007/978-1-4939-8772-6_4">10.1007/978-1-4939-8772-6_4</a>'
  apa: Zagórski, M. P., &#38; Kicheva, A. (2018). Measuring dorsoventral pattern and
    morphogen signaling profiles in the growing neural tube. In <i>Morphogen Gradients
    </i> (Vol. 1863, pp. 47–63). Springer Nature. <a href="https://doi.org/10.1007/978-1-4939-8772-6_4">https://doi.org/10.1007/978-1-4939-8772-6_4</a>
  chicago: Zagórski, Marcin P, and Anna Kicheva. “Measuring Dorsoventral Pattern and
    Morphogen Signaling Profiles in the Growing Neural Tube.” In <i>Morphogen Gradients
    </i>, 1863:47–63. MIMB. Springer Nature, 2018. <a href="https://doi.org/10.1007/978-1-4939-8772-6_4">https://doi.org/10.1007/978-1-4939-8772-6_4</a>.
  ieee: M. P. Zagórski and A. Kicheva, “Measuring dorsoventral pattern and morphogen
    signaling profiles in the growing neural tube,” in <i>Morphogen Gradients </i>,
    vol. 1863, Springer Nature, 2018, pp. 47–63.
  ista: 'Zagórski MP, Kicheva A. 2018.Measuring dorsoventral pattern and morphogen
    signaling profiles in the growing neural tube. In: Morphogen Gradients . Methods
    in Molecular Biology, vol. 1863, 47–63.'
  mla: Zagórski, Marcin P., and Anna Kicheva. “Measuring Dorsoventral Pattern and
    Morphogen Signaling Profiles in the Growing Neural Tube.” <i>Morphogen Gradients
    </i>, vol. 1863, Springer Nature, 2018, pp. 47–63, doi:<a href="https://doi.org/10.1007/978-1-4939-8772-6_4">10.1007/978-1-4939-8772-6_4</a>.
  short: M.P. Zagórski, A. Kicheva, in:, Morphogen Gradients , Springer Nature, 2018,
    pp. 47–63.
date_created: 2018-12-11T11:44:17Z
date_published: 2018-10-16T00:00:00Z
date_updated: 2021-01-12T07:49:03Z
day: '16'
ddc:
- '570'
department:
- _id: AnKi
doi: 10.1007/978-1-4939-8772-6_4
ec_funded: 1
file:
- access_level: open_access
  checksum: 2a97d0649fdcfcf1bdca7c8ad1dce71b
  content_type: application/pdf
  creator: dernst
  date_created: 2020-10-13T14:20:37Z
  date_updated: 2020-10-13T14:20:37Z
  file_id: '8656'
  file_name: 2018_MIMB_Zagorski.pdf
  file_size: 4906815
  relation: main_file
  success: 1
file_date_updated: 2020-10-13T14:20:37Z
has_accepted_license: '1'
intvolume: '      1863'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Submitted Version
page: 47 - 63
project:
- _id: B6FC0238-B512-11E9-945C-1524E6697425
  call_identifier: H2020
  grant_number: '680037'
  name: Coordination of Patterning And Growth In the Spinal Cord
publication: 'Morphogen Gradients '
publication_identifier:
  isbn:
  - 978-1-4939-8771-9
  issn:
  - 1064-3745
publication_status: published
publisher: Springer Nature
publist_id: '8018'
quality_controlled: '1'
scopus_import: '1'
series_title: MIMB
status: public
title: Measuring dorsoventral pattern and morphogen signaling profiles in the growing
  neural tube
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 1863
year: '2018'
...
---
_id: '38'
abstract:
- lang: eng
  text: 'Genomes of closely-related species or populations often display localized
    regions of enhanced relative sequence divergence, termed genomic islands. It has
    been proposed that these islands arise through selective sweeps and/or barriers
    to gene flow. Here, we genetically dissect a genomic island that controls flower
    color pattern differences between two subspecies of Antirrhinum majus, A.m.striatum
    and A.m.pseudomajus, and relate it to clinal variation across a natural hybrid
    zone. We show that selective sweeps likely raised relative divergence at two tightly-linked
    MYB-like transcription factors, leading to distinct flower patterns in the two
    subspecies. The two patterns provide alternate floral guides and create a strong
    barrier to gene flow where populations come into contact. This barrier affects
    the selected flower color genes and tightlylinked loci, but does not extend outside
    of this domain, allowing gene flow to lower relative divergence for the rest of
    the chromosome. Thus, both selective sweeps and barriers to gene flow play a role
    in shaping genomic islands: sweeps cause elevation in relative divergence, while
    heterogeneous gene flow flattens the surrounding "sea," making the island of divergence
    stand out. By showing how selective sweeps establish alternative adaptive phenotypes
    that lead to barriers to gene flow, our study sheds light on possible mechanisms
    leading to reproductive isolation and speciation.'
acknowledgement: ' ERC Grant 201252 (to N.H.B.)'
article_processing_charge: No
author:
- first_name: Hugo
  full_name: Tavares, Hugo
  last_name: Tavares
- first_name: Annabel
  full_name: Whitley, Annabel
  last_name: Whitley
- first_name: David
  full_name: Field, David
  id: 419049E2-F248-11E8-B48F-1D18A9856A87
  last_name: Field
  orcid: 0000-0002-4014-8478
- first_name: Desmond
  full_name: Bradley, Desmond
  last_name: Bradley
- first_name: Matthew
  full_name: Couchman, Matthew
  last_name: Couchman
- first_name: Lucy
  full_name: Copsey, Lucy
  last_name: Copsey
- first_name: Joane
  full_name: Elleouet, Joane
  last_name: Elleouet
- first_name: Monique
  full_name: Burrus, Monique
  last_name: Burrus
- first_name: Christophe
  full_name: Andalo, Christophe
  last_name: Andalo
- first_name: Miaomiao
  full_name: Li, Miaomiao
  last_name: Li
- first_name: Qun
  full_name: Li, Qun
  last_name: Li
- first_name: Yongbiao
  full_name: Xue, Yongbiao
  last_name: Xue
- first_name: Alexandra B
  full_name: Rebocho, Alexandra B
  last_name: Rebocho
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Enrico
  full_name: Coen, Enrico
  last_name: Coen
citation:
  ama: Tavares H, Whitley A, Field D, et al. Selection and gene flow shape genomic
    islands that control floral guides. <i>PNAS</i>. 2018;115(43):11006-11011. doi:<a
    href="https://doi.org/10.1073/pnas.1801832115">10.1073/pnas.1801832115</a>
  apa: Tavares, H., Whitley, A., Field, D., Bradley, D., Couchman, M., Copsey, L.,
    … Coen, E. (2018). Selection and gene flow shape genomic islands that control
    floral guides. <i>PNAS</i>. National Academy of Sciences. <a href="https://doi.org/10.1073/pnas.1801832115">https://doi.org/10.1073/pnas.1801832115</a>
  chicago: Tavares, Hugo, Annabel Whitley, David Field, Desmond Bradley, Matthew Couchman,
    Lucy Copsey, Joane Elleouet, et al. “Selection and Gene Flow Shape Genomic Islands
    That Control Floral Guides.” <i>PNAS</i>. National Academy of Sciences, 2018.
    <a href="https://doi.org/10.1073/pnas.1801832115">https://doi.org/10.1073/pnas.1801832115</a>.
  ieee: H. Tavares <i>et al.</i>, “Selection and gene flow shape genomic islands that
    control floral guides,” <i>PNAS</i>, vol. 115, no. 43. National Academy of Sciences,
    pp. 11006–11011, 2018.
  ista: Tavares H, Whitley A, Field D, Bradley D, Couchman M, Copsey L, Elleouet J,
    Burrus M, Andalo C, Li M, Li Q, Xue Y, Rebocho AB, Barton NH, Coen E. 2018. Selection
    and gene flow shape genomic islands that control floral guides. PNAS. 115(43),
    11006–11011.
  mla: Tavares, Hugo, et al. “Selection and Gene Flow Shape Genomic Islands That Control
    Floral Guides.” <i>PNAS</i>, vol. 115, no. 43, National Academy of Sciences, 2018,
    pp. 11006–11, doi:<a href="https://doi.org/10.1073/pnas.1801832115">10.1073/pnas.1801832115</a>.
  short: H. Tavares, A. Whitley, D. Field, D. Bradley, M. Couchman, L. Copsey, J.
    Elleouet, M. Burrus, C. Andalo, M. Li, Q. Li, Y. Xue, A.B. Rebocho, N.H. Barton,
    E. Coen, PNAS 115 (2018) 11006–11011.
date_created: 2018-12-11T11:44:18Z
date_published: 2018-10-23T00:00:00Z
date_updated: 2023-09-18T08:36:49Z
day: '23'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1073/pnas.1801832115
external_id:
  isi:
  - '000448040500065'
  pmid:
  - '30297406'
file:
- access_level: open_access
  checksum: d2305d0cc81dbbe4c1c677d64ad6f6d1
  content_type: application/pdf
  creator: dernst
  date_created: 2018-12-17T08:44:03Z
  date_updated: 2020-07-14T12:46:16Z
  file_id: '5683'
  file_name: 11006.full.pdf
  file_size: 1911302
  relation: main_file
file_date_updated: 2020-07-14T12:46:16Z
has_accepted_license: '1'
intvolume: '       115'
isi: 1
issue: '43'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '10'
oa: 1
oa_version: Published Version
page: 11006 - 11011
pmid: 1
publication: PNAS
publication_identifier:
  issn:
  - '00278424'
publication_status: published
publisher: National Academy of Sciences
publist_id: '8017'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Selection and gene flow shape genomic islands that control floral guides
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 115
year: '2018'
...
---
_id: '384'
abstract:
- lang: eng
  text: Can orthologous proteins differ in terms of their ability to be secreted?
    To answer this question, we investigated the distribution of signal peptides within
    the orthologous groups of Enterobacterales. Parsimony analysis and sequence comparisons
    revealed a large number of signal peptide gain and loss events, in which signal
    peptides emerge or disappear in the course of evolution. Signal peptide losses
    prevail over gains, an effect which is especially pronounced in the transition
    from the free-living or commensal to the endosymbiotic lifestyle. The disproportionate
    decline in the number of signal peptide-containing proteins in endosymbionts cannot
    be explained by the overall reduction of their genomes. Signal peptides can be
    gained and lost either by acquisition/elimination of the corresponding N-terminal
    regions or by gradual accumulation of mutations. The evolutionary dynamics of
    signal peptides in bacterial proteins represents a powerful mechanism of functional
    diversification.
acknowledgement: "his work was supported by the Deutsche Forschungsgemeinschaft  (grant
  \ number  FR  1411/9-1).  This work  was  supported  by  the  German  Research  Foundation
  (DFG) and the Technical University of Munich within the fund- ing programme Open
  Access Publish\r\nWe thank Goar Frishman for help with the annotation of the\r\nsymbiont
  status of the organisms and Michael Galperin for\r\nuseful comments. T"
article_processing_charge: No
author:
- first_name: Peter
  full_name: Hönigschmid, Peter
  last_name: Hönigschmid
- first_name: Nadya
  full_name: Bykova, Nadya
  last_name: Bykova
- first_name: René
  full_name: Schneider, René
  last_name: Schneider
- first_name: Dmitry
  full_name: Ivankov, Dmitry
  id: 49FF1036-F248-11E8-B48F-1D18A9856A87
  last_name: Ivankov
- first_name: Dmitrij
  full_name: Frishman, Dmitrij
  last_name: Frishman
citation:
  ama: Hönigschmid P, Bykova N, Schneider R, Ivankov D, Frishman D. Evolutionary interplay
    between symbiotic relationships and patterns of signal peptide gain and loss.
    <i>Genome Biology and Evolution</i>. 2018;10(3):928-938. doi:<a href="https://doi.org/10.1093/gbe/evy049">10.1093/gbe/evy049</a>
  apa: Hönigschmid, P., Bykova, N., Schneider, R., Ivankov, D., &#38; Frishman, D.
    (2018). Evolutionary interplay between symbiotic relationships and patterns of
    signal peptide gain and loss. <i>Genome Biology and Evolution</i>. Oxford University
    Press. <a href="https://doi.org/10.1093/gbe/evy049">https://doi.org/10.1093/gbe/evy049</a>
  chicago: Hönigschmid, Peter, Nadya Bykova, René Schneider, Dmitry Ivankov, and Dmitrij
    Frishman. “Evolutionary Interplay between Symbiotic Relationships and Patterns
    of Signal Peptide Gain and Loss.” <i>Genome Biology and Evolution</i>. Oxford
    University Press, 2018. <a href="https://doi.org/10.1093/gbe/evy049">https://doi.org/10.1093/gbe/evy049</a>.
  ieee: P. Hönigschmid, N. Bykova, R. Schneider, D. Ivankov, and D. Frishman, “Evolutionary
    interplay between symbiotic relationships and patterns of signal peptide gain
    and loss,” <i>Genome Biology and Evolution</i>, vol. 10, no. 3. Oxford University
    Press, pp. 928–938, 2018.
  ista: Hönigschmid P, Bykova N, Schneider R, Ivankov D, Frishman D. 2018. Evolutionary
    interplay between symbiotic relationships and patterns of signal peptide gain
    and loss. Genome Biology and Evolution. 10(3), 928–938.
  mla: Hönigschmid, Peter, et al. “Evolutionary Interplay between Symbiotic Relationships
    and Patterns of Signal Peptide Gain and Loss.” <i>Genome Biology and Evolution</i>,
    vol. 10, no. 3, Oxford University Press, 2018, pp. 928–38, doi:<a href="https://doi.org/10.1093/gbe/evy049">10.1093/gbe/evy049</a>.
  short: P. Hönigschmid, N. Bykova, R. Schneider, D. Ivankov, D. Frishman, Genome
    Biology and Evolution 10 (2018) 928–938.
date_created: 2018-12-11T11:46:10Z
date_published: 2018-03-01T00:00:00Z
date_updated: 2023-09-11T13:56:52Z
day: '01'
ddc:
- '576'
department:
- _id: FyKo
doi: 10.1093/gbe/evy049
external_id:
  isi:
  - '000429483700022'
file:
- access_level: open_access
  checksum: 458a7c2c2e79528567edfeb0f326cbe0
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:08:07Z
  date_updated: 2020-07-14T12:46:16Z
  file_id: '4667'
  file_name: IST-2018-999-v1+1_2018_Ivankov_Evolutionary_interplay.pdf
  file_size: 691602
  relation: main_file
file_date_updated: 2020-07-14T12:46:16Z
has_accepted_license: '1'
intvolume: '        10'
isi: 1
issue: '3'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 928 - 938
publication: Genome Biology and Evolution
publication_status: published
publisher: Oxford University Press
publist_id: '7445'
pubrep_id: '999'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Evolutionary interplay between symbiotic relationships and patterns of signal
  peptide gain and loss
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 10
year: '2018'
...
---
_id: '39'
abstract:
- lang: eng
  text: We study how a block of genome with a large number of weakly selected loci
    introgresses under directional selection into a genetically homogeneous population.
    We derive exact expressions for the expected rate of growth of any fragment of
    the introduced block during the initial phase of introgression, and show that
    the growth rate of a single-locus variant is largely insensitive to its own additive
    effect, but depends instead on the combined effect of all loci within a characteristic
    linkage scale. The expected growth rate of a fragment is highly correlated with
    its long-term introgression probability in populations of moderate size, and can
    hence identify variants that are likely to introgress across replicate populations.
    We clarify how the introgression probability of an individual variant is determined
    by the interplay between hitchhiking with relatively large fragments during the
    early phase of introgression and selection on fine-scale variation within these,
    which at longer times results in differential introgression probabilities for
    beneficial and deleterious loci within successful fragments. By simulating individuals,
    we also investigate how introgression probabilities at individual loci depend
    on the variance of fitness effects, the net fitness of the introduced block, and
    the size of the recipient population, and how this shapes the net advance under
    selection. Our work suggests that even highly replicable substitutions may be
    associated with a range of selective effects, which makes it challenging to fine
    map the causal loci that underlie polygenic adaptation.
article_processing_charge: No
article_type: original
author:
- first_name: Himani
  full_name: Sachdeva, Himani
  id: 42377A0A-F248-11E8-B48F-1D18A9856A87
  last_name: Sachdeva
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
citation:
  ama: Sachdeva H, Barton NH. Replicability of introgression under linked, polygenic
    selection. <i>Genetics</i>. 2018;210(4):1411-1427. doi:<a href="https://doi.org/10.1534/genetics.118.301429">10.1534/genetics.118.301429</a>
  apa: Sachdeva, H., &#38; Barton, N. H. (2018). Replicability of introgression under
    linked, polygenic selection. <i>Genetics</i>. Genetics Society of America. <a
    href="https://doi.org/10.1534/genetics.118.301429">https://doi.org/10.1534/genetics.118.301429</a>
  chicago: Sachdeva, Himani, and Nicholas H Barton. “Replicability of Introgression
    under Linked, Polygenic Selection.” <i>Genetics</i>. Genetics Society of America,
    2018. <a href="https://doi.org/10.1534/genetics.118.301429">https://doi.org/10.1534/genetics.118.301429</a>.
  ieee: H. Sachdeva and N. H. Barton, “Replicability of introgression under linked,
    polygenic selection,” <i>Genetics</i>, vol. 210, no. 4. Genetics Society of America,
    pp. 1411–1427, 2018.
  ista: Sachdeva H, Barton NH. 2018. Replicability of introgression under linked,
    polygenic selection. Genetics. 210(4), 1411–1427.
  mla: Sachdeva, Himani, and Nicholas H. Barton. “Replicability of Introgression under
    Linked, Polygenic Selection.” <i>Genetics</i>, vol. 210, no. 4, Genetics Society
    of America, 2018, pp. 1411–27, doi:<a href="https://doi.org/10.1534/genetics.118.301429">10.1534/genetics.118.301429</a>.
  short: H. Sachdeva, N.H. Barton, Genetics 210 (2018) 1411–1427.
date_created: 2018-12-11T11:44:18Z
date_published: 2018-12-04T00:00:00Z
date_updated: 2023-09-18T08:10:29Z
day: '04'
department:
- _id: NiBa
doi: 10.1534/genetics.118.301429
external_id:
  isi:
  - '000452315900021'
intvolume: '       210'
isi: 1
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.biorxiv.org/content/10.1101/379578v1
month: '12'
oa: 1
oa_version: Preprint
page: 1411-1427
publication: Genetics
publication_identifier:
  issn:
  - '00166731'
publication_status: published
publisher: Genetics Society of America
quality_controlled: '1'
scopus_import: '1'
status: public
title: Replicability of introgression under linked, polygenic selection
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 210
year: '2018'
...
---
_id: '394'
abstract:
- lang: eng
  text: 'The valley pseudospin in monolayer transition metal dichalcogenides (TMDs)
    has been proposed as a new way to manipulate information in various optoelectronic
    devices. This relies on a large valley polarization that remains stable over long
    time scales (hundreds of nanoseconds). However, time-resolved measurements report
    valley lifetimes of only a few picoseconds. This has been attributed to mechanisms
    such as phonon-mediated intervalley scattering and a precession of the valley
    pseudospin through electron-hole exchange. Here we use transient spin grating
    to directly measure the valley depolarization lifetime in monolayer MoSe2. We
    find a fast valley decay rate that scales linearly with the excitation density
    at different temperatures. This establishes the presence of strong exciton-exciton
    Coulomb exchange interactions enhancing the valley depolarization. Our work highlights
    the microscopic processes inhibiting the efficient use of the exciton valley pseudospin
    in monolayer TMDs. '
arxiv: 1
author:
- first_name: Fahad
  full_name: Mahmood, Fahad
  last_name: Mahmood
- first_name: Zhanybek
  full_name: Alpichshev, Zhanybek
  id: 45E67A2A-F248-11E8-B48F-1D18A9856A87
  last_name: Alpichshev
  orcid: 0000-0002-7183-5203
- first_name: Yi
  full_name: Lee, Yi
  last_name: Lee
- first_name: Jing
  full_name: Kong, Jing
  last_name: Kong
- first_name: Nuh
  full_name: Gedik, Nuh
  last_name: Gedik
citation:
  ama: Mahmood F, Alpichshev Z, Lee Y, Kong J, Gedik N. Observation of exciton-exciton
    interaction mediated valley Depolarization in Monolayer MoSe2. <i>Nano Letters</i>.
    2018;18(1):223-228. doi:<a href="https://doi.org/10.1021/acs.nanolett.7b03953">10.1021/acs.nanolett.7b03953</a>
  apa: Mahmood, F., Alpichshev, Z., Lee, Y., Kong, J., &#38; Gedik, N. (2018). Observation
    of exciton-exciton interaction mediated valley Depolarization in Monolayer MoSe2.
    <i>Nano Letters</i>. American Chemical Society. <a href="https://doi.org/10.1021/acs.nanolett.7b03953">https://doi.org/10.1021/acs.nanolett.7b03953</a>
  chicago: Mahmood, Fahad, Zhanybek Alpichshev, Yi Lee, Jing Kong, and Nuh Gedik.
    “Observation of Exciton-Exciton Interaction Mediated Valley Depolarization in
    Monolayer MoSe2.” <i>Nano Letters</i>. American Chemical Society, 2018. <a href="https://doi.org/10.1021/acs.nanolett.7b03953">https://doi.org/10.1021/acs.nanolett.7b03953</a>.
  ieee: F. Mahmood, Z. Alpichshev, Y. Lee, J. Kong, and N. Gedik, “Observation of
    exciton-exciton interaction mediated valley Depolarization in Monolayer MoSe2,”
    <i>Nano Letters</i>, vol. 18, no. 1. American Chemical Society, pp. 223–228, 2018.
  ista: Mahmood F, Alpichshev Z, Lee Y, Kong J, Gedik N. 2018. Observation of exciton-exciton
    interaction mediated valley Depolarization in Monolayer MoSe2. Nano Letters. 18(1),
    223–228.
  mla: Mahmood, Fahad, et al. “Observation of Exciton-Exciton Interaction Mediated
    Valley Depolarization in Monolayer MoSe2.” <i>Nano Letters</i>, vol. 18, no. 1,
    American Chemical Society, 2018, pp. 223–28, doi:<a href="https://doi.org/10.1021/acs.nanolett.7b03953">10.1021/acs.nanolett.7b03953</a>.
  short: F. Mahmood, Z. Alpichshev, Y. Lee, J. Kong, N. Gedik, Nano Letters 18 (2018)
    223–228.
date_created: 2018-12-11T11:46:13Z
date_published: 2018-01-10T00:00:00Z
date_updated: 2021-01-12T07:53:20Z
day: '10'
doi: 10.1021/acs.nanolett.7b03953
extern: '1'
external_id:
  arxiv:
  - '1712.07925'
intvolume: '        18'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1712.07925
month: '01'
oa: 1
oa_version: Submitted Version
page: 223 - 228
publication: Nano Letters
publication_status: published
publisher: American Chemical Society
publist_id: '7435'
quality_controlled: '1'
status: public
title: Observation of exciton-exciton interaction mediated valley Depolarization in
  Monolayer MoSe2
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 18
year: '2018'
...
---
_id: '395'
abstract:
- lang: eng
  text: 'Autism spectrum disorders (ASD) are a group of genetic disorders often overlapping
    with other neurological conditions. Despite the remarkable number of scientific
    breakthroughs of the last 100 years, the treatment of neurodevelopmental disorders
    (e.g. autism spectrum disorder, intellectual disability, epilepsy) remains a great
    challenge. Recent advancements in geno mics, like whole-exome or whole-genome
    sequencing, have enabled scientists to identify numerous mutations underlying
    neurodevelopmental disorders. Given the few hundred risk genes that were discovered,
    the etiological variability and the heterogeneous phenotypic outcomes, the need
    for genotype -along with phenotype- based diagnosis of individual patients becomes
    a requisite. Driven by this rationale, in a previous study our group described
    mutations, identified via whole - exome sequencing, in the gene BCKDK – encoding
    for a key regulator of branched chain amin o acid (BCAA) catabolism - as a cause
    of ASD. Following up on the role of BCAAs, in the study described here we show
    that the solute carrier transporter 7a5 (SLC7A5), a large neutral amino acid transporter
    localized mainly at the blood brain barrier (BBB), has an essential role in maintaining
    normal levels of brain BCAAs. In mice, deletion of Slc7a5 from the endothelial
    cells of the BBB leads to atypical brain amino acid profile, abnormal mRNA translation
    and severe neurolo gical abnormalities. Additionally, deletion of Slc7a5 from
    the neural progenitor cell population leads to microcephaly. Interestingly, we
    demonstrate that BCAA intracerebroventricular administration ameliorates abnormal
    behaviors in adult mutant mice. Furthermore, whole - exome sequencing of patients
    diagnosed with neurological dis o r ders helped us identify several patients with
    autistic traits, microcephaly and motor delay carrying deleterious homozygous
    mutations in the SLC7A5 gene. In conclusion, our data elucidate a neurological
    syndrome defined by SLC7A5 mutations and support an essential role for t he BCAA
    s in human bra in function. Together with r ecent studies (described in chapter
    two) that have successfully made the transition into clinical practice, our findings
    on the role of B CAAs might have a crucial impact on the development of novel
    individualized therapeutic strategies for ASD. '
acknowledged_ssus:
- _id: PreCl
- _id: EM-Fac
- _id: Bio
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Dora-Clara
  full_name: Tarlungeanu, Dora-Clara
  id: 2ABCE612-F248-11E8-B48F-1D18A9856A87
  last_name: Tarlungeanu
citation:
  ama: Tarlungeanu D-C. The branched chain amino acids in autism spectrum disorders
    . 2018. doi:<a href="https://doi.org/10.15479/AT:ISTA:th_992">10.15479/AT:ISTA:th_992</a>
  apa: Tarlungeanu, D.-C. (2018). <i>The branched chain amino acids in autism spectrum
    disorders </i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:th_992">https://doi.org/10.15479/AT:ISTA:th_992</a>
  chicago: Tarlungeanu, Dora-Clara. “The Branched Chain Amino Acids in Autism Spectrum
    Disorders .” Institute of Science and Technology Austria, 2018. <a href="https://doi.org/10.15479/AT:ISTA:th_992">https://doi.org/10.15479/AT:ISTA:th_992</a>.
  ieee: D.-C. Tarlungeanu, “The branched chain amino acids in autism spectrum disorders
    ,” Institute of Science and Technology Austria, 2018.
  ista: Tarlungeanu D-C. 2018. The branched chain amino acids in autism spectrum disorders
    . Institute of Science and Technology Austria.
  mla: Tarlungeanu, Dora-Clara. <i>The Branched Chain Amino Acids in Autism Spectrum
    Disorders </i>. Institute of Science and Technology Austria, 2018, doi:<a href="https://doi.org/10.15479/AT:ISTA:th_992">10.15479/AT:ISTA:th_992</a>.
  short: D.-C. Tarlungeanu, The Branched Chain Amino Acids in Autism Spectrum Disorders
    , Institute of Science and Technology Austria, 2018.
date_created: 2018-12-11T11:46:14Z
date_published: 2018-03-01T00:00:00Z
date_updated: 2023-09-07T12:38:59Z
day: '01'
ddc:
- '570'
- '616'
degree_awarded: PhD
department:
- _id: GaNo
doi: 10.15479/AT:ISTA:th_992
file:
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  date_created: 2019-04-05T09:19:17Z
  date_updated: 2021-02-11T11:17:16Z
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file_date_updated: 2021-02-11T23:30:15Z
has_accepted_license: '1'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: '88'
project:
- _id: 25473368-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: F03523
  name: Transmembrane Transporters in Health and Disease
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
publist_id: '7434'
pubrep_id: '992'
related_material:
  record:
  - id: '1183'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Gaia
  full_name: Novarino, Gaia
  id: 3E57A680-F248-11E8-B48F-1D18A9856A87
  last_name: Novarino
  orcid: 0000-0002-7673-7178
title: 'The branched chain amino acids in autism spectrum disorders '
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2018'
...
---
_id: '397'
abstract:
- lang: eng
  text: 'Concurrent sets with range query operations are highly desirable in applications
    such as in-memory databases. However, few set implementations offer range queries.
    Known techniques for augmenting data structures with range queries (or operations
    that can be used to build range queries) have numerous problems that limit their
    usefulness. For example, they impose high overhead or rely heavily on garbage
    collection. In this work, we show how to augment data structures with highly efficient
    range queries, without relying on garbage collection. We identify a property of
    epoch-based memory reclamation algorithms that makes them ideal for implementing
    range queries, and produce three algorithms, which use locks, transactional memory
    and lock-free techniques, respectively. Our algorithms are applicable to more
    data structures than previous work, and are shown to be highly efficient on a
    large scale Intel system. '
alternative_title:
- PPoPP
article_processing_charge: No
author:
- first_name: Maya
  full_name: Arbel Raviv, Maya
  last_name: Arbel Raviv
- first_name: Trevor A
  full_name: Brown, Trevor A
  id: 3569F0A0-F248-11E8-B48F-1D18A9856A87
  last_name: Brown
citation:
  ama: 'Arbel Raviv M, Brown TA. Harnessing epoch-based reclamation for efficient
    range queries. In: Vol 53. ACM; 2018:14-27. doi:<a href="https://doi.org/10.1145/3178487.3178489">10.1145/3178487.3178489</a>'
  apa: 'Arbel Raviv, M., &#38; Brown, T. A. (2018). Harnessing epoch-based reclamation
    for efficient range queries (Vol. 53, pp. 14–27). Presented at the PPoPP: Principles
    and Practice of Parallel Programming, Vienna, Austria: ACM. <a href="https://doi.org/10.1145/3178487.3178489">https://doi.org/10.1145/3178487.3178489</a>'
  chicago: Arbel Raviv, Maya, and Trevor A Brown. “Harnessing Epoch-Based Reclamation
    for Efficient Range Queries,” 53:14–27. ACM, 2018. <a href="https://doi.org/10.1145/3178487.3178489">https://doi.org/10.1145/3178487.3178489</a>.
  ieee: 'M. Arbel Raviv and T. A. Brown, “Harnessing epoch-based reclamation for efficient
    range queries,” presented at the PPoPP: Principles and Practice of Parallel Programming,
    Vienna, Austria, 2018, vol. 53, no. 1, pp. 14–27.'
  ista: 'Arbel Raviv M, Brown TA. 2018. Harnessing epoch-based reclamation for efficient
    range queries. PPoPP: Principles and Practice of Parallel Programming, PPoPP,
    vol. 53, 14–27.'
  mla: Arbel Raviv, Maya, and Trevor A. Brown. <i>Harnessing Epoch-Based Reclamation
    for Efficient Range Queries</i>. Vol. 53, no. 1, ACM, 2018, pp. 14–27, doi:<a
    href="https://doi.org/10.1145/3178487.3178489">10.1145/3178487.3178489</a>.
  short: M. Arbel Raviv, T.A. Brown, in:, ACM, 2018, pp. 14–27.
conference:
  end_date: 2018-02-28
  location: Vienna, Austria
  name: 'PPoPP: Principles and Practice of Parallel Programming'
  start_date: 2018-02-24
date_created: 2018-12-11T11:46:14Z
date_published: 2018-02-10T00:00:00Z
date_updated: 2023-09-11T14:10:25Z
day: '10'
department:
- _id: DaAl
doi: 10.1145/3178487.3178489
external_id:
  isi:
  - '000446161100002'
intvolume: '        53'
isi: 1
issue: '1'
language:
- iso: eng
month: '02'
oa_version: None
page: 14 - 27
publication_identifier:
  isbn:
  - 978-1-4503-4982-6
publication_status: published
publisher: ACM
publist_id: '7430'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Harnessing epoch-based reclamation for efficient range queries
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 53
year: '2018'
...
