---
_id: '9812'
abstract:
- lang: eng
  text: This document contains the full list of genes with their respective significance
    and dN/dS values. (TXT 4499Â kb)
article_processing_charge: No
author:
- first_name: Luis
  full_name: Zapata, Luis
  last_name: Zapata
- first_name: Oriol
  full_name: Pich, Oriol
  last_name: Pich
- first_name: Luis
  full_name: Serrano, Luis
  last_name: Serrano
- first_name: Fyodor
  full_name: Kondrashov, Fyodor
  id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
  last_name: Kondrashov
  orcid: 0000-0001-8243-4694
- first_name: Stephan
  full_name: Ossowski, Stephan
  last_name: Ossowski
- first_name: Martin
  full_name: Schaefer, Martin
  last_name: Schaefer
citation:
  ama: 'Zapata L, Pich O, Serrano L, Kondrashov F, Ossowski S, Schaefer M. Additional
    file 2: Of negative selection in tumor genome evolution acts on essential cellular
    functions and the immunopeptidome. 2018. doi:<a href="https://doi.org/10.6084/m9.figshare.6401414.v1">10.6084/m9.figshare.6401414.v1</a>'
  apa: 'Zapata, L., Pich, O., Serrano, L., Kondrashov, F., Ossowski, S., &#38; Schaefer,
    M. (2018). Additional file 2: Of negative selection in tumor genome evolution
    acts on essential cellular functions and the immunopeptidome. Springer Nature.
    <a href="https://doi.org/10.6084/m9.figshare.6401414.v1">https://doi.org/10.6084/m9.figshare.6401414.v1</a>'
  chicago: 'Zapata, Luis, Oriol Pich, Luis Serrano, Fyodor Kondrashov, Stephan Ossowski,
    and Martin Schaefer. “Additional File 2: Of Negative Selection in Tumor Genome
    Evolution Acts on Essential Cellular Functions and the Immunopeptidome.” Springer
    Nature, 2018. <a href="https://doi.org/10.6084/m9.figshare.6401414.v1">https://doi.org/10.6084/m9.figshare.6401414.v1</a>.'
  ieee: 'L. Zapata, O. Pich, L. Serrano, F. Kondrashov, S. Ossowski, and M. Schaefer,
    “Additional file 2: Of negative selection in tumor genome evolution acts on essential
    cellular functions and the immunopeptidome.” Springer Nature, 2018.'
  ista: 'Zapata L, Pich O, Serrano L, Kondrashov F, Ossowski S, Schaefer M. 2018.
    Additional file 2: Of negative selection in tumor genome evolution acts on essential
    cellular functions and the immunopeptidome, Springer Nature, <a href="https://doi.org/10.6084/m9.figshare.6401414.v1">10.6084/m9.figshare.6401414.v1</a>.'
  mla: 'Zapata, Luis, et al. <i>Additional File 2: Of Negative Selection in Tumor
    Genome Evolution Acts on Essential Cellular Functions and the Immunopeptidome</i>.
    Springer Nature, 2018, doi:<a href="https://doi.org/10.6084/m9.figshare.6401414.v1">10.6084/m9.figshare.6401414.v1</a>.'
  short: L. Zapata, O. Pich, L. Serrano, F. Kondrashov, S. Ossowski, M. Schaefer,
    (2018).
date_created: 2021-08-06T12:58:25Z
date_published: 2018-05-31T00:00:00Z
date_updated: 2023-09-13T09:01:31Z
day: '31'
department:
- _id: FyKo
doi: 10.6084/m9.figshare.6401414.v1
main_file_link:
- open_access: '1'
  url: https://doi.org/10.6084/m9.figshare.6401414.v1
month: '05'
oa: 1
oa_version: Published Version
publisher: Springer Nature
related_material:
  record:
  - id: '279'
    relation: used_in_publication
    status: public
status: public
title: 'Additional file 2: Of negative selection in tumor genome evolution acts on
  essential cellular functions and the immunopeptidome'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2018'
...
---
_id: '9813'
abstract:
- lang: eng
  text: 'File S1 contains figures that clarify the following features: (i) effect
    of population size on the average number/frequency of SI classes, (ii) changes
    in the minimal completeness deficit in time for a single class, and (iii) diversification
    diagrams for all studied pathways, including the summary figure for k = 8. File
    S2 contains the code required for a stochastic simulation of the SLF system with
    an example. This file also includes the output in the form of figures and tables.'
article_processing_charge: No
author:
- first_name: Katarína
  full_name: Bod'ová, Katarína
  id: 2BA24EA0-F248-11E8-B48F-1D18A9856A87
  last_name: Bod'ová
  orcid: 0000-0002-7214-0171
- first_name: Tadeas
  full_name: Priklopil, Tadeas
  id: 3C869AA0-F248-11E8-B48F-1D18A9856A87
  last_name: Priklopil
- first_name: David
  full_name: Field, David
  id: 419049E2-F248-11E8-B48F-1D18A9856A87
  last_name: Field
  orcid: 0000-0002-4014-8478
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Melinda
  full_name: Pickup, Melinda
  id: 2C78037E-F248-11E8-B48F-1D18A9856A87
  last_name: Pickup
  orcid: 0000-0001-6118-0541
citation:
  ama: Bodova K, Priklopil T, Field D, Barton NH, Pickup M. Supplemental material
    for Bodova et al., 2018. 2018. doi:<a href="https://doi.org/10.25386/genetics.6148304.v1">10.25386/genetics.6148304.v1</a>
  apa: Bodova, K., Priklopil, T., Field, D., Barton, N. H., &#38; Pickup, M. (2018).
    Supplemental material for Bodova et al., 2018. Genetics Society of America. <a
    href="https://doi.org/10.25386/genetics.6148304.v1">https://doi.org/10.25386/genetics.6148304.v1</a>
  chicago: Bodova, Katarina, Tadeas Priklopil, David Field, Nicholas H Barton, and
    Melinda Pickup. “Supplemental Material for Bodova et Al., 2018.” Genetics Society
    of America, 2018. <a href="https://doi.org/10.25386/genetics.6148304.v1">https://doi.org/10.25386/genetics.6148304.v1</a>.
  ieee: K. Bodova, T. Priklopil, D. Field, N. H. Barton, and M. Pickup, “Supplemental
    material for Bodova et al., 2018.” Genetics Society of America, 2018.
  ista: Bodova K, Priklopil T, Field D, Barton NH, Pickup M. 2018. Supplemental material
    for Bodova et al., 2018, Genetics Society of America, <a href="https://doi.org/10.25386/genetics.6148304.v1">10.25386/genetics.6148304.v1</a>.
  mla: Bodova, Katarina, et al. <i>Supplemental Material for Bodova et Al., 2018</i>.
    Genetics Society of America, 2018, doi:<a href="https://doi.org/10.25386/genetics.6148304.v1">10.25386/genetics.6148304.v1</a>.
  short: K. Bodova, T. Priklopil, D. Field, N.H. Barton, M. Pickup, (2018).
date_created: 2021-08-06T13:04:32Z
date_published: 2018-04-30T00:00:00Z
date_updated: 2025-05-28T11:57:01Z
day: '30'
department:
- _id: NiBa
- _id: GaTk
doi: 10.25386/genetics.6148304.v1
main_file_link:
- open_access: '1'
  url: https://doi.org/10.25386/genetics.6148304.v1
month: '04'
oa: 1
oa_version: Published Version
publisher: Genetics Society of America
related_material:
  record:
  - id: '316'
    relation: used_in_publication
    status: public
status: public
title: Supplemental material for Bodova et al., 2018
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2018'
...
---
_id: '9831'
abstract:
- lang: eng
  text: 'Implementation of the inference method in Matlab, including three applications
    of the method: The first one for the model of ant motion, the second one for bacterial
    chemotaxis, and the third one for the motion of fish.'
article_processing_charge: No
author:
- first_name: Katarína
  full_name: Bod’Ová, Katarína
  last_name: Bod’Ová
- first_name: Gabriel
  full_name: Mitchell, Gabriel
  id: 315BCD80-F248-11E8-B48F-1D18A9856A87
  last_name: Mitchell
- first_name: Roy
  full_name: Harpaz, Roy
  last_name: Harpaz
- first_name: Elad
  full_name: Schneidman, Elad
  last_name: Schneidman
- first_name: Gašper
  full_name: Tkačik, Gašper
  id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
  last_name: Tkačik
  orcid: 0000-0002-6699-1455
citation:
  ama: Bod’Ová K, Mitchell G, Harpaz R, Schneidman E, Tkačik G. Implementation of
    the inference method in Matlab. 2018. doi:<a href="https://doi.org/10.1371/journal.pone.0193049.s001">10.1371/journal.pone.0193049.s001</a>
  apa: Bod’Ová, K., Mitchell, G., Harpaz, R., Schneidman, E., &#38; Tkačik, G. (2018).
    Implementation of the inference method in Matlab. Public Library of Science. <a
    href="https://doi.org/10.1371/journal.pone.0193049.s001">https://doi.org/10.1371/journal.pone.0193049.s001</a>
  chicago: Bod’Ová, Katarína, Gabriel Mitchell, Roy Harpaz, Elad Schneidman, and Gašper
    Tkačik. “Implementation of the Inference Method in Matlab.” Public Library of
    Science, 2018. <a href="https://doi.org/10.1371/journal.pone.0193049.s001">https://doi.org/10.1371/journal.pone.0193049.s001</a>.
  ieee: K. Bod’Ová, G. Mitchell, R. Harpaz, E. Schneidman, and G. Tkačik, “Implementation
    of the inference method in Matlab.” Public Library of Science, 2018.
  ista: Bod’Ová K, Mitchell G, Harpaz R, Schneidman E, Tkačik G. 2018. Implementation
    of the inference method in Matlab, Public Library of Science, <a href="https://doi.org/10.1371/journal.pone.0193049.s001">10.1371/journal.pone.0193049.s001</a>.
  mla: Bod’Ová, Katarína, et al. <i>Implementation of the Inference Method in Matlab</i>.
    Public Library of Science, 2018, doi:<a href="https://doi.org/10.1371/journal.pone.0193049.s001">10.1371/journal.pone.0193049.s001</a>.
  short: K. Bod’Ová, G. Mitchell, R. Harpaz, E. Schneidman, G. Tkačik, (2018).
date_created: 2021-08-09T07:01:24Z
date_published: 2018-03-07T00:00:00Z
date_updated: 2023-09-15T12:06:18Z
day: '07'
department:
- _id: GaTk
doi: 10.1371/journal.pone.0193049.s001
month: '03'
oa_version: Published Version
publisher: Public Library of Science
related_material:
  record:
  - id: '406'
    relation: used_in_publication
    status: public
status: public
title: Implementation of the inference method in Matlab
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2018'
...
---
_id: '9837'
abstract:
- lang: eng
  text: Both classical and recent studies suggest that chromosomal inversion polymorphisms
    are important in adaptation and speciation. However, biases in discovery and reporting
    of inversions make it difficult to assess their prevalence and biological importance.
    Here, we use an approach based on linkage disequilibrium among markers genotyped
    for samples collected across a transect between contrasting habitats to detect
    chromosomal rearrangements de novo. We report 17 polymorphic rearrangements in
    a single locality for the coastal marine snail, Littorina saxatilis. Patterns
    of diversity in the field and of recombination in controlled crosses provide strong
    evidence that at least the majority of these rearrangements are inversions. Most
    show clinal changes in frequency between habitats, suggestive of divergent selection,
    but only one appears to be fixed for different arrangements in the two habitats.
    Consistent with widespread evidence for balancing selection on inversion polymorphisms,
    we argue that a combination of heterosis and divergent selection can explain the
    observed patterns and should be considered in other systems spanning environmental
    gradients.
article_processing_charge: No
author:
- first_name: Rui
  full_name: Faria, Rui
  last_name: Faria
- first_name: Pragya
  full_name: Chaube, Pragya
  last_name: Chaube
- first_name: Hernán E.
  full_name: Morales, Hernán E.
  last_name: Morales
- first_name: Tomas
  full_name: Larsson, Tomas
  last_name: Larsson
- first_name: Alan R.
  full_name: Lemmon, Alan R.
  last_name: Lemmon
- first_name: Emily M.
  full_name: Lemmon, Emily M.
  last_name: Lemmon
- first_name: Marina
  full_name: Rafajlović, Marina
  last_name: Rafajlović
- first_name: Marina
  full_name: Panova, Marina
  last_name: Panova
- first_name: Mark
  full_name: Ravinet, Mark
  last_name: Ravinet
- first_name: Kerstin
  full_name: Johannesson, Kerstin
  last_name: Johannesson
- first_name: Anja M
  full_name: Westram, Anja M
  id: 3C147470-F248-11E8-B48F-1D18A9856A87
  last_name: Westram
  orcid: 0000-0003-1050-4969
- first_name: Roger K.
  full_name: Butlin, Roger K.
  last_name: Butlin
citation:
  ama: 'Faria R, Chaube P, Morales HE, et al. Data from: Multiple chromosomal rearrangements
    in a hybrid zone between Littorina saxatilis ecotypes. 2018. doi:<a href="https://doi.org/10.5061/dryad.72cg113">10.5061/dryad.72cg113</a>'
  apa: 'Faria, R., Chaube, P., Morales, H. E., Larsson, T., Lemmon, A. R., Lemmon,
    E. M., … Butlin, R. K. (2018). Data from: Multiple chromosomal rearrangements
    in a hybrid zone between Littorina saxatilis ecotypes. Dryad. <a href="https://doi.org/10.5061/dryad.72cg113">https://doi.org/10.5061/dryad.72cg113</a>'
  chicago: 'Faria, Rui, Pragya Chaube, Hernán E. Morales, Tomas Larsson, Alan R. Lemmon,
    Emily M. Lemmon, Marina Rafajlović, et al. “Data from: Multiple Chromosomal Rearrangements
    in a Hybrid Zone between Littorina Saxatilis Ecotypes.” Dryad, 2018. <a href="https://doi.org/10.5061/dryad.72cg113">https://doi.org/10.5061/dryad.72cg113</a>.'
  ieee: 'R. Faria <i>et al.</i>, “Data from: Multiple chromosomal rearrangements in
    a hybrid zone between Littorina saxatilis ecotypes.” Dryad, 2018.'
  ista: 'Faria R, Chaube P, Morales HE, Larsson T, Lemmon AR, Lemmon EM, Rafajlović
    M, Panova M, Ravinet M, Johannesson K, Westram AM, Butlin RK. 2018. Data from:
    Multiple chromosomal rearrangements in a hybrid zone between Littorina saxatilis
    ecotypes, Dryad, <a href="https://doi.org/10.5061/dryad.72cg113">10.5061/dryad.72cg113</a>.'
  mla: 'Faria, Rui, et al. <i>Data from: Multiple Chromosomal Rearrangements in a
    Hybrid Zone between Littorina Saxatilis Ecotypes</i>. Dryad, 2018, doi:<a href="https://doi.org/10.5061/dryad.72cg113">10.5061/dryad.72cg113</a>.'
  short: R. Faria, P. Chaube, H.E. Morales, T. Larsson, A.R. Lemmon, E.M. Lemmon,
    M. Rafajlović, M. Panova, M. Ravinet, K. Johannesson, A.M. Westram, R.K. Butlin,
    (2018).
date_created: 2021-08-09T12:46:39Z
date_published: 2018-10-09T00:00:00Z
date_updated: 2023-08-24T14:50:26Z
day: '09'
department:
- _id: NiBa
doi: 10.5061/dryad.72cg113
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5061/dryad.72cg113
month: '10'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
  record:
  - id: '6095'
    relation: used_in_publication
    status: public
status: public
title: 'Data from: Multiple chromosomal rearrangements in a hybrid zone between Littorina
  saxatilis ecotypes'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2018'
...
---
_id: '9838'
abstract:
- lang: eng
  text: 'Facial shape is the basis for facial recognition and categorization. Facial
    features reflect the underlying geometry of the skeletal structures. Here we reveal
    that cartilaginous nasal capsule (corresponding to upper jaw and face) is shaped
    by signals generated by neural structures: brain and olfactory epithelium. Brain-derived
    Sonic Hedgehog (SHH) enables the induction of nasal septum and posterior nasal
    capsule, whereas the formation of a capsule roof is controlled by signals from
    the olfactory epithelium. Unexpectedly, the cartilage of the nasal capsule turned
    out to be important for shaping membranous facial bones during development. This
    suggests that conserved neurosensory structures could benefit from protection
    and have evolved signals inducing cranial cartilages encasing them. Experiments
    with mutant mice revealed that the genomic regulatory regions controlling production
    of SHH in the nervous system contribute to facial cartilage morphogenesis, which
    might be a mechanism responsible for the adaptive evolution of animal faces and
    snouts.'
article_processing_charge: No
author:
- first_name: Marketa
  full_name: Kaucka, Marketa
  last_name: Kaucka
- first_name: Julian
  full_name: Petersen, Julian
  last_name: Petersen
- first_name: Marketa
  full_name: Tesarova, Marketa
  last_name: Tesarova
- first_name: Bara
  full_name: Szarowska, Bara
  last_name: Szarowska
- first_name: Maria Eleni
  full_name: Kastriti, Maria Eleni
  last_name: Kastriti
- first_name: Meng
  full_name: Xie, Meng
  last_name: Xie
- first_name: Anna
  full_name: Kicheva, Anna
  id: 3959A2A0-F248-11E8-B48F-1D18A9856A87
  last_name: Kicheva
  orcid: 0000-0003-4509-4998
- first_name: Karl
  full_name: Annusver, Karl
  last_name: Annusver
- first_name: Maria
  full_name: Kasper, Maria
  last_name: Kasper
- first_name: Orsolya
  full_name: Symmons, Orsolya
  last_name: Symmons
- first_name: Leslie
  full_name: Pan, Leslie
  last_name: Pan
- first_name: Francois
  full_name: Spitz, Francois
  last_name: Spitz
- first_name: Jozef
  full_name: Kaiser, Jozef
  last_name: Kaiser
- first_name: Maria
  full_name: Hovorakova, Maria
  last_name: Hovorakova
- first_name: Tomas
  full_name: Zikmund, Tomas
  last_name: Zikmund
- first_name: Kazunori
  full_name: Sunadome, Kazunori
  last_name: Sunadome
- first_name: Michael P
  full_name: Matise, Michael P
  last_name: Matise
- first_name: Hui
  full_name: Wang, Hui
  last_name: Wang
- first_name: Ulrika
  full_name: Marklund, Ulrika
  last_name: Marklund
- first_name: Hind
  full_name: Abdo, Hind
  last_name: Abdo
- first_name: Patrik
  full_name: Ernfors, Patrik
  last_name: Ernfors
- first_name: Pascal
  full_name: Maire, Pascal
  last_name: Maire
- first_name: Maud
  full_name: Wurmser, Maud
  last_name: Wurmser
- first_name: Andrei S
  full_name: Chagin, Andrei S
  last_name: Chagin
- first_name: Kaj
  full_name: Fried, Kaj
  last_name: Fried
- first_name: Igor
  full_name: Adameyko, Igor
  last_name: Adameyko
citation:
  ama: 'Kaucka M, Petersen J, Tesarova M, et al. Data from: Signals from the brain
    and olfactory epithelium control shaping of the mammalian nasal capsule cartilage.
    2018. doi:<a href="https://doi.org/10.5061/dryad.f1s76f2">10.5061/dryad.f1s76f2</a>'
  apa: 'Kaucka, M., Petersen, J., Tesarova, M., Szarowska, B., Kastriti, M. E., Xie,
    M., … Adameyko, I. (2018). Data from: Signals from the brain and olfactory epithelium
    control shaping of the mammalian nasal capsule cartilage. Dryad. <a href="https://doi.org/10.5061/dryad.f1s76f2">https://doi.org/10.5061/dryad.f1s76f2</a>'
  chicago: 'Kaucka, Marketa, Julian Petersen, Marketa Tesarova, Bara Szarowska, Maria
    Eleni Kastriti, Meng Xie, Anna Kicheva, et al. “Data from: Signals from the Brain
    and Olfactory Epithelium Control Shaping of the Mammalian Nasal Capsule Cartilage.”
    Dryad, 2018. <a href="https://doi.org/10.5061/dryad.f1s76f2">https://doi.org/10.5061/dryad.f1s76f2</a>.'
  ieee: 'M. Kaucka <i>et al.</i>, “Data from: Signals from the brain and olfactory
    epithelium control shaping of the mammalian nasal capsule cartilage.” Dryad, 2018.'
  ista: 'Kaucka M, Petersen J, Tesarova M, Szarowska B, Kastriti ME, Xie M, Kicheva
    A, Annusver K, Kasper M, Symmons O, Pan L, Spitz F, Kaiser J, Hovorakova M, Zikmund
    T, Sunadome K, Matise MP, Wang H, Marklund U, Abdo H, Ernfors P, Maire P, Wurmser
    M, Chagin AS, Fried K, Adameyko I. 2018. Data from: Signals from the brain and
    olfactory epithelium control shaping of the mammalian nasal capsule cartilage,
    Dryad, <a href="https://doi.org/10.5061/dryad.f1s76f2">10.5061/dryad.f1s76f2</a>.'
  mla: 'Kaucka, Marketa, et al. <i>Data from: Signals from the Brain and Olfactory
    Epithelium Control Shaping of the Mammalian Nasal Capsule Cartilage</i>. Dryad,
    2018, doi:<a href="https://doi.org/10.5061/dryad.f1s76f2">10.5061/dryad.f1s76f2</a>.'
  short: M. Kaucka, J. Petersen, M. Tesarova, B. Szarowska, M.E. Kastriti, M. Xie,
    A. Kicheva, K. Annusver, M. Kasper, O. Symmons, L. Pan, F. Spitz, J. Kaiser, M.
    Hovorakova, T. Zikmund, K. Sunadome, M.P. Matise, H. Wang, U. Marklund, H. Abdo,
    P. Ernfors, P. Maire, M. Wurmser, A.S. Chagin, K. Fried, I. Adameyko, (2018).
date_created: 2021-08-09T12:54:35Z
date_published: 2018-06-14T00:00:00Z
date_updated: 2023-09-18T09:29:07Z
day: '14'
department:
- _id: AnKi
doi: 10.5061/dryad.f1s76f2
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5061/dryad.f1s76f2
month: '06'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
  record:
  - id: '162'
    relation: used_in_publication
    status: public
status: public
title: 'Data from: Signals from the brain and olfactory epithelium control shaping
  of the mammalian nasal capsule cartilage'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2018'
...
---
_id: '9840'
abstract:
- lang: eng
  text: Herd immunity, a process in which resistant individuals limit the spread of
    a pathogen among susceptible hosts has been extensively studied in eukaryotes.
    Even though bacteria have evolved multiple immune systems against their phage
    pathogens, herd immunity in bacteria remains unexplored. Here we experimentally
    demonstrate that herd immunity arises during phage epidemics in structured and
    unstructured Escherichia coli populations consisting of differing frequencies
    of susceptible and resistant cells harboring CRISPR immunity. In addition, we
    develop a mathematical model that quantifies how herd immunity is affected by
    spatial population structure, bacterial growth rate, and phage replication rate.
    Using our model we infer a general epidemiological rule describing the relative
    speed of an epidemic in partially resistant spatially structured populations.
    Our experimental and theoretical findings indicate that herd immunity may be important
    in bacterial communities, allowing for stable coexistence of bacteria and their
    phages and the maintenance of polymorphism in bacterial immunity.
article_processing_charge: No
author:
- first_name: Pavel
  full_name: Payne, Pavel
  id: 35F78294-F248-11E8-B48F-1D18A9856A87
  last_name: Payne
  orcid: 0000-0002-2711-9453
- first_name: Lukas
  full_name: Geyrhofer, Lukas
  last_name: Geyrhofer
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Jonathan P
  full_name: Bollback, Jonathan P
  id: 2C6FA9CC-F248-11E8-B48F-1D18A9856A87
  last_name: Bollback
  orcid: 0000-0002-4624-4612
citation:
  ama: 'Payne P, Geyrhofer L, Barton NH, Bollback JP. Data from: CRISPR-based herd
    immunity limits phage epidemics in bacterial populations. 2018. doi:<a href="https://doi.org/10.5061/dryad.42n44">10.5061/dryad.42n44</a>'
  apa: 'Payne, P., Geyrhofer, L., Barton, N. H., &#38; Bollback, J. P. (2018). Data
    from: CRISPR-based herd immunity limits phage epidemics in bacterial populations.
    Dryad. <a href="https://doi.org/10.5061/dryad.42n44">https://doi.org/10.5061/dryad.42n44</a>'
  chicago: 'Payne, Pavel, Lukas Geyrhofer, Nicholas H Barton, and Jonathan P Bollback.
    “Data from: CRISPR-Based Herd Immunity Limits Phage Epidemics in Bacterial Populations.”
    Dryad, 2018. <a href="https://doi.org/10.5061/dryad.42n44">https://doi.org/10.5061/dryad.42n44</a>.'
  ieee: 'P. Payne, L. Geyrhofer, N. H. Barton, and J. P. Bollback, “Data from: CRISPR-based
    herd immunity limits phage epidemics in bacterial populations.” Dryad, 2018.'
  ista: 'Payne P, Geyrhofer L, Barton NH, Bollback JP. 2018. Data from: CRISPR-based
    herd immunity limits phage epidemics in bacterial populations, Dryad, <a href="https://doi.org/10.5061/dryad.42n44">10.5061/dryad.42n44</a>.'
  mla: 'Payne, Pavel, et al. <i>Data from: CRISPR-Based Herd Immunity Limits Phage
    Epidemics in Bacterial Populations</i>. Dryad, 2018, doi:<a href="https://doi.org/10.5061/dryad.42n44">10.5061/dryad.42n44</a>.'
  short: P. Payne, L. Geyrhofer, N.H. Barton, J.P. Bollback, (2018).
date_created: 2021-08-09T13:10:02Z
date_published: 2018-03-12T00:00:00Z
date_updated: 2023-09-11T12:49:17Z
day: '12'
department:
- _id: NiBa
- _id: JoBo
doi: 10.5061/dryad.42n44
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5061/dryad.42n44
month: '03'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
  record:
  - id: '423'
    relation: used_in_publication
    status: public
status: public
title: 'Data from: CRISPR-based herd immunity limits phage epidemics in bacterial
  populations'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2018'
...
---
_id: '9841'
abstract:
- lang: eng
  text: Around 150 million years ago, eusocial termites evolved from within the cockroaches,
    50 million years before eusocial Hymenoptera, such as bees and ants, appeared.
    Here, we report the 2-Gb genome of the German cockroach, Blattella germanica,
    and the 1.3-Gb genome of the drywood termite Cryptotermes secundus. We show evolutionary
    signatures of termite eusociality by comparing the genomes and transcriptomes
    of three termites and the cockroach against the background of 16 other eusocial
    and non-eusocial insects. Dramatic adaptive changes in genes underlying the production
    and perception of pheromones confirm the importance of chemical communication
    in the termites. These are accompanied by major changes in gene regulation and
    the molecular evolution of caste determination. Many of these results parallel
    molecular mechanisms of eusocial evolution in Hymenoptera. However, the specific
    solutions are remarkably different, thus revealing a striking case of convergence
    in one of the major evolutionary transitions in biological complexity.
article_processing_charge: No
author:
- first_name: Mark C.
  full_name: Harrison, Mark C.
  last_name: Harrison
- first_name: Evelien
  full_name: Jongepier, Evelien
  last_name: Jongepier
- first_name: Hugh M.
  full_name: Robertson, Hugh M.
  last_name: Robertson
- first_name: Nicolas
  full_name: Arning, Nicolas
  last_name: Arning
- first_name: Tristan
  full_name: Bitard-Feildel, Tristan
  last_name: Bitard-Feildel
- first_name: Hsu
  full_name: Chao, Hsu
  last_name: Chao
- first_name: Christopher P.
  full_name: Childers, Christopher P.
  last_name: Childers
- first_name: Huyen
  full_name: Dinh, Huyen
  last_name: Dinh
- first_name: Harshavardhan
  full_name: Doddapaneni, Harshavardhan
  last_name: Doddapaneni
- first_name: Shannon
  full_name: Dugan, Shannon
  last_name: Dugan
- first_name: Johannes
  full_name: Gowin, Johannes
  last_name: Gowin
- first_name: Carolin
  full_name: Greiner, Carolin
  last_name: Greiner
- first_name: Yi
  full_name: Han, Yi
  last_name: Han
- first_name: Haofu
  full_name: Hu, Haofu
  last_name: Hu
- first_name: Daniel S. T.
  full_name: Hughes, Daniel S. T.
  last_name: Hughes
- first_name: Ann K
  full_name: Huylmans, Ann K
  id: 4C0A3874-F248-11E8-B48F-1D18A9856A87
  last_name: Huylmans
  orcid: 0000-0001-8871-4961
- first_name: Carsten
  full_name: Kemena, Carsten
  last_name: Kemena
- first_name: Lukas P. M.
  full_name: Kremer, Lukas P. M.
  last_name: Kremer
- first_name: Sandra L.
  full_name: Lee, Sandra L.
  last_name: Lee
- first_name: Alberto
  full_name: Lopez-Ezquerra, Alberto
  last_name: Lopez-Ezquerra
- first_name: Ludovic
  full_name: Mallet, Ludovic
  last_name: Mallet
- first_name: Jose M.
  full_name: Monroy-Kuhn, Jose M.
  last_name: Monroy-Kuhn
- first_name: Annabell
  full_name: Moser, Annabell
  last_name: Moser
- first_name: Shwetha C.
  full_name: Murali, Shwetha C.
  last_name: Murali
- first_name: Donna M.
  full_name: Muzny, Donna M.
  last_name: Muzny
- first_name: Saria
  full_name: Otani, Saria
  last_name: Otani
- first_name: Maria-Dolors
  full_name: Piulachs, Maria-Dolors
  last_name: Piulachs
- first_name: Monica
  full_name: Poelchau, Monica
  last_name: Poelchau
- first_name: Jiaxin
  full_name: Qu, Jiaxin
  last_name: Qu
- first_name: Florentine
  full_name: Schaub, Florentine
  last_name: Schaub
- first_name: Ayako
  full_name: Wada-Katsumata, Ayako
  last_name: Wada-Katsumata
- first_name: Kim C.
  full_name: Worley, Kim C.
  last_name: Worley
- first_name: Qiaolin
  full_name: Xie, Qiaolin
  last_name: Xie
- first_name: Guillem
  full_name: Ylla, Guillem
  last_name: Ylla
- first_name: Michael
  full_name: Poulsen, Michael
  last_name: Poulsen
- first_name: Richard A.
  full_name: Gibbs, Richard A.
  last_name: Gibbs
- first_name: Coby
  full_name: Schal, Coby
  last_name: Schal
- first_name: Stephen
  full_name: Richards, Stephen
  last_name: Richards
- first_name: Xavier
  full_name: Belles, Xavier
  last_name: Belles
- first_name: Judith
  full_name: Korb, Judith
  last_name: Korb
- first_name: Erich
  full_name: Bornberg-Bauer, Erich
  last_name: Bornberg-Bauer
citation:
  ama: 'Harrison MC, Jongepier E, Robertson HM, et al. Data from: Hemimetabolous genomes
    reveal molecular basis of termite eusociality. 2018. doi:<a href="https://doi.org/10.5061/dryad.51d4r">10.5061/dryad.51d4r</a>'
  apa: 'Harrison, M. C., Jongepier, E., Robertson, H. M., Arning, N., Bitard-Feildel,
    T., Chao, H., … Bornberg-Bauer, E. (2018). Data from: Hemimetabolous genomes reveal
    molecular basis of termite eusociality. Dryad. <a href="https://doi.org/10.5061/dryad.51d4r">https://doi.org/10.5061/dryad.51d4r</a>'
  chicago: 'Harrison, Mark C., Evelien Jongepier, Hugh M. Robertson, Nicolas Arning,
    Tristan Bitard-Feildel, Hsu Chao, Christopher P. Childers, et al. “Data from:
    Hemimetabolous Genomes Reveal Molecular Basis of Termite Eusociality.” Dryad,
    2018. <a href="https://doi.org/10.5061/dryad.51d4r">https://doi.org/10.5061/dryad.51d4r</a>.'
  ieee: 'M. C. Harrison <i>et al.</i>, “Data from: Hemimetabolous genomes reveal molecular
    basis of termite eusociality.” Dryad, 2018.'
  ista: 'Harrison MC, Jongepier E, Robertson HM, Arning N, Bitard-Feildel T, Chao
    H, Childers CP, Dinh H, Doddapaneni H, Dugan S, Gowin J, Greiner C, Han Y, Hu
    H, Hughes DST, Huylmans AK, Kemena C, Kremer LPM, Lee SL, Lopez-Ezquerra A, Mallet
    L, Monroy-Kuhn JM, Moser A, Murali SC, Muzny DM, Otani S, Piulachs M-D, Poelchau
    M, Qu J, Schaub F, Wada-Katsumata A, Worley KC, Xie Q, Ylla G, Poulsen M, Gibbs
    RA, Schal C, Richards S, Belles X, Korb J, Bornberg-Bauer E. 2018. Data from:
    Hemimetabolous genomes reveal molecular basis of termite eusociality, Dryad, <a
    href="https://doi.org/10.5061/dryad.51d4r">10.5061/dryad.51d4r</a>.'
  mla: 'Harrison, Mark C., et al. <i>Data from: Hemimetabolous Genomes Reveal Molecular
    Basis of Termite Eusociality</i>. Dryad, 2018, doi:<a href="https://doi.org/10.5061/dryad.51d4r">10.5061/dryad.51d4r</a>.'
  short: M.C. Harrison, E. Jongepier, H.M. Robertson, N. Arning, T. Bitard-Feildel,
    H. Chao, C.P. Childers, H. Dinh, H. Doddapaneni, S. Dugan, J. Gowin, C. Greiner,
    Y. Han, H. Hu, D.S.T. Hughes, A.K. Huylmans, C. Kemena, L.P.M. Kremer, S.L. Lee,
    A. Lopez-Ezquerra, L. Mallet, J.M. Monroy-Kuhn, A. Moser, S.C. Murali, D.M. Muzny,
    S. Otani, M.-D. Piulachs, M. Poelchau, J. Qu, F. Schaub, A. Wada-Katsumata, K.C.
    Worley, Q. Xie, G. Ylla, M. Poulsen, R.A. Gibbs, C. Schal, S. Richards, X. Belles,
    J. Korb, E. Bornberg-Bauer, (2018).
date_created: 2021-08-09T13:13:48Z
date_published: 2018-12-12T00:00:00Z
date_updated: 2023-09-11T14:10:56Z
day: '12'
department:
- _id: BeVi
doi: 10.5061/dryad.51d4r
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5061/dryad.51d4r
month: '12'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
  record:
  - id: '448'
    relation: used_in_publication
    status: public
status: public
title: 'Data from: Hemimetabolous genomes reveal molecular basis of termite eusociality'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2018'
...
---
_id: '9915'
abstract:
- lang: eng
  text: 'The evolution of assortative mating is a key part of the speciation process.
    Stronger assortment, or greater divergence in mating traits, between species pairs
    with overlapping ranges is commonly observed, but possible causes of this pattern
    of reproductive character displacement are difficult to distinguish. We use a
    multidisciplinary approach to provide a rare example where it is possible to distinguish
    among hypotheses concerning the evolution of reproductive character displacement.
    We build on an earlier comparative analysis that illustrated a strong pattern
    of greater divergence in penis form between pairs of sister species with overlapping
    ranges than between allopatric sister-species pairs, in a large clade of marine
    gastropods (Littorinidae). We investigate both assortative mating and divergence
    in male genitalia in one of the sister-species pairs, discriminating among three
    contrasting processes each of which can generate a pattern of reproductive character
    displacement: reinforcement, reproductive interference and the Templeton effect.
    We demonstrate reproductive character displacement in assortative mating, but
    not in genital form between this pair of sister species and use demographic models
    to distinguish among the different processes. Our results support a model with
    no gene flow since secondary contact and thus favor reproductive interference
    as the cause of reproductive character displacement for mate choice, rather than
    reinforcement. High gene flow within species argues against the Templeton effect.
    Secondary contact appears to have had little impact on genital divergence.'
acknowledgement: The authors express a special thanks to Dr Richard Willan at the
  Museum and Art Gallery of the Northern Territory for guidance and support in the
  field, and to Carole Smadja for reading and commenting on the manuscript. The authors
  thank the Government of Western Australia Department of Parks and Wildlife (license
  no. 009254) and Fishery Research Division (exemption no. 2262) for assistance with
  permits. Khalid Belkhir modified the coalescent sampler msnsam for the specific
  needs of this project and Martin Hirsch helped to set up the ABC pipeline and to
  modify the summary statistic calculator mscalc. The authors are grateful to the
  Crafoord Foundation for supporting this project. R.K.B., A.M.W., and L.D. were supported
  by grants from the Natural Environment Research Council, R.K.B. and A.M.W. were
  also supported by the European Research Council and R.K.B. and L.D. by the Leverhulme
  Trust. M.M.R. was supported by Consejo Nacional de Ciencia y Tecnología and Secretaría
  de Educación Pública, Mexico. G.B. was supported by the Centre for Animal Movement
  Research (CAnMove) financed by a Linnaeus grant (No. 349-2007-8690) from the Swedish
  Research Council and Lund University.
article_processing_charge: Yes
article_type: letter_note
author:
- first_name: Johan
  full_name: Hollander, Johan
  last_name: Hollander
- first_name: Mauricio
  full_name: Montaño-Rendón, Mauricio
  last_name: Montaño-Rendón
- first_name: Giuseppe
  full_name: Bianco, Giuseppe
  last_name: Bianco
- first_name: Xi
  full_name: Yang, Xi
  last_name: Yang
- first_name: Anja M
  full_name: Westram, Anja M
  id: 3C147470-F248-11E8-B48F-1D18A9856A87
  last_name: Westram
  orcid: 0000-0003-1050-4969
- first_name: Ludovic
  full_name: Duvaux, Ludovic
  last_name: Duvaux
- first_name: David G.
  full_name: Reid, David G.
  last_name: Reid
- first_name: Roger K.
  full_name: Butlin, Roger K.
  last_name: Butlin
citation:
  ama: Hollander J, Montaño-Rendón M, Bianco G, et al. Are assortative mating and
    genital divergence driven by reinforcement? <i>Evolution Letters</i>. 2018;2(6):557-566.
    doi:<a href="https://doi.org/10.1002/evl3.85">10.1002/evl3.85</a>
  apa: Hollander, J., Montaño-Rendón, M., Bianco, G., Yang, X., Westram, A. M., Duvaux,
    L., … Butlin, R. K. (2018). Are assortative mating and genital divergence driven
    by reinforcement? <i>Evolution Letters</i>. Wiley. <a href="https://doi.org/10.1002/evl3.85">https://doi.org/10.1002/evl3.85</a>
  chicago: Hollander, Johan, Mauricio Montaño-Rendón, Giuseppe Bianco, Xi Yang, Anja
    M Westram, Ludovic Duvaux, David G. Reid, and Roger K. Butlin. “Are Assortative
    Mating and Genital Divergence Driven by Reinforcement?” <i>Evolution Letters</i>.
    Wiley, 2018. <a href="https://doi.org/10.1002/evl3.85">https://doi.org/10.1002/evl3.85</a>.
  ieee: J. Hollander <i>et al.</i>, “Are assortative mating and genital divergence
    driven by reinforcement?,” <i>Evolution Letters</i>, vol. 2, no. 6. Wiley, pp.
    557–566, 2018.
  ista: Hollander J, Montaño-Rendón M, Bianco G, Yang X, Westram AM, Duvaux L, Reid
    DG, Butlin RK. 2018. Are assortative mating and genital divergence driven by reinforcement?
    Evolution Letters. 2(6), 557–566.
  mla: Hollander, Johan, et al. “Are Assortative Mating and Genital Divergence Driven
    by Reinforcement?” <i>Evolution Letters</i>, vol. 2, no. 6, Wiley, 2018, pp. 557–66,
    doi:<a href="https://doi.org/10.1002/evl3.85">10.1002/evl3.85</a>.
  short: J. Hollander, M. Montaño-Rendón, G. Bianco, X. Yang, A.M. Westram, L. Duvaux,
    D.G. Reid, R.K. Butlin, Evolution Letters 2 (2018) 557–566.
date_created: 2021-08-16T07:30:00Z
date_published: 2018-12-13T00:00:00Z
date_updated: 2023-09-19T15:08:53Z
day: '13'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.1002/evl3.85
external_id:
  isi:
  - '000452990000002'
  pmid:
  - '30564439'
file:
- access_level: open_access
  checksum: 997a78ac41c809975ca69cbdea441f88
  content_type: application/pdf
  creator: asandaue
  date_created: 2021-08-16T07:37:28Z
  date_updated: 2021-08-16T07:37:28Z
  file_id: '9916'
  file_name: 2018_EvolutionLetters_Hollander.pdf
  file_size: 584606
  relation: main_file
  success: 1
file_date_updated: 2021-08-16T07:37:28Z
has_accepted_license: '1'
intvolume: '         2'
isi: 1
issue: '6'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 557-566
pmid: 1
publication: Evolution Letters
publication_identifier:
  eissn:
  - 2056-3744
  issn:
  - ' 2056-3744'
publication_status: published
publisher: Wiley
quality_controlled: '1'
related_material:
  record:
  - id: '9929'
    relation: research_data
    status: public
status: public
title: Are assortative mating and genital divergence driven by reinforcement?
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 2
year: '2018'
...
---
_id: '9917'
abstract:
- lang: eng
  text: Adaptive divergence and speciation may happen despite opposition by gene flow.
    Identifying the genomic basis underlying divergence with gene flow is a major
    task in evolutionary genomics. Most approaches (e.g., outlier scans) focus on
    genomic regions of high differentiation. However, not all genomic architectures
    potentially underlying divergence are expected to show extreme differentiation.
    Here, we develop an approach that combines hybrid zone analysis (i.e., focuses
    on spatial patterns of allele frequency change) with system-specific simulations
    to identify loci inconsistent with neutral evolution. We apply this to a genome-wide
    SNP set from an ideally suited study organism, the intertidal snail Littorina
    saxatilis, which shows primary divergence between ecotypes associated with different
    shore habitats. We detect many SNPs with clinal patterns, most of which are consistent
    with neutrality. Among non-neutral SNPs, most are located within three large putative
    inversions differentiating ecotypes. Many non-neutral SNPs show relatively low
    levels of differentiation. We discuss potential reasons for this pattern, including
    loose linkage to selected variants, polygenic adaptation and a component of balancing
    selection within populations (which may be expected for inversions). Our work
    is in line with theory predicting a role for inversions in divergence, and emphasizes
    that genomic regions contributing to divergence may not always be accessible with
    methods purely based on allele frequency differences. These conclusions call for
    approaches that take spatial patterns of allele frequency change into account
    in other systems.
acknowledgement: We are very grateful to people who helped with fieldwork, snail processing,
  and DNA extractions, particularly Laura Brettell, Mårten Duvetorp, Juan Galindo,
  Anne-Lise Liabot and Irena Senčić. We would also like to thank Magnus Alm Rosenblad
  and Mats Töpel for their contribution to assembling the Littorina saxatilis genome,
  Carl André, Pasi Rastas, and Romain Villoutreix for discussion, and two anonymous
  reviewers for their helpful comments on the manuscript. We are grateful to RapidGenomics
  for library preparation and sequencing. We thank the Natural Environment Research
  Council, the European Research Council and the Swedish Research Councils VR and
  Formas (Linnaeus grant to the Centre for Marine Evolutionary Biology and Tage Erlander
  Guest Professorship) for funding. P.C. was funded by the University of Sheffield
  Vice-chancellor's India scholarship. R.F. is funded by the European Union's Horizon
  2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement
  no. 706376. M. Raf. was supported by the Adlerbert Research Foundation.
article_processing_charge: Yes
article_type: letter_note
author:
- first_name: Anja M
  full_name: Westram, Anja M
  id: 3C147470-F248-11E8-B48F-1D18A9856A87
  last_name: Westram
  orcid: 0000-0003-1050-4969
- first_name: Marina
  full_name: Rafajlović, Marina
  last_name: Rafajlović
- first_name: Pragya
  full_name: Chaube, Pragya
  last_name: Chaube
- first_name: Rui
  full_name: Faria, Rui
  last_name: Faria
- first_name: Tomas
  full_name: Larsson, Tomas
  last_name: Larsson
- first_name: Marina
  full_name: Panova, Marina
  last_name: Panova
- first_name: Mark
  full_name: Ravinet, Mark
  last_name: Ravinet
- first_name: Anders
  full_name: Blomberg, Anders
  last_name: Blomberg
- first_name: Bernhard
  full_name: Mehlig, Bernhard
  last_name: Mehlig
- first_name: Kerstin
  full_name: Johannesson, Kerstin
  last_name: Johannesson
- first_name: Roger
  full_name: Butlin, Roger
  last_name: Butlin
citation:
  ama: 'Westram AM, Rafajlović M, Chaube P, et al. Clines on the seashore: The genomic
    architecture underlying rapid divergence in the face of gene flow. <i>Evolution
    Letters</i>. 2018;2(4):297-309. doi:<a href="https://doi.org/10.1002/evl3.74">10.1002/evl3.74</a>'
  apa: 'Westram, A. M., Rafajlović, M., Chaube, P., Faria, R., Larsson, T., Panova,
    M., … Butlin, R. (2018). Clines on the seashore: The genomic architecture underlying
    rapid divergence in the face of gene flow. <i>Evolution Letters</i>. Wiley. <a
    href="https://doi.org/10.1002/evl3.74">https://doi.org/10.1002/evl3.74</a>'
  chicago: 'Westram, Anja M, Marina Rafajlović, Pragya Chaube, Rui Faria, Tomas Larsson,
    Marina Panova, Mark Ravinet, et al. “Clines on the Seashore: The Genomic Architecture
    Underlying Rapid Divergence in the Face of Gene Flow.” <i>Evolution Letters</i>.
    Wiley, 2018. <a href="https://doi.org/10.1002/evl3.74">https://doi.org/10.1002/evl3.74</a>.'
  ieee: 'A. M. Westram <i>et al.</i>, “Clines on the seashore: The genomic architecture
    underlying rapid divergence in the face of gene flow,” <i>Evolution Letters</i>,
    vol. 2, no. 4. Wiley, pp. 297–309, 2018.'
  ista: 'Westram AM, Rafajlović M, Chaube P, Faria R, Larsson T, Panova M, Ravinet
    M, Blomberg A, Mehlig B, Johannesson K, Butlin R. 2018. Clines on the seashore:
    The genomic architecture underlying rapid divergence in the face of gene flow.
    Evolution Letters. 2(4), 297–309.'
  mla: 'Westram, Anja M., et al. “Clines on the Seashore: The Genomic Architecture
    Underlying Rapid Divergence in the Face of Gene Flow.” <i>Evolution Letters</i>,
    vol. 2, no. 4, Wiley, 2018, pp. 297–309, doi:<a href="https://doi.org/10.1002/evl3.74">10.1002/evl3.74</a>.'
  short: A.M. Westram, M. Rafajlović, P. Chaube, R. Faria, T. Larsson, M. Panova,
    M. Ravinet, A. Blomberg, B. Mehlig, K. Johannesson, R. Butlin, Evolution Letters
    2 (2018) 297–309.
date_created: 2021-08-16T07:45:38Z
date_published: 2018-08-20T00:00:00Z
date_updated: 2023-09-19T15:08:25Z
day: '20'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.1002/evl3.74
external_id:
  isi:
  - '000446774400004'
  pmid:
  - '30283683'
file:
- access_level: open_access
  checksum: 8524e72507d521416be3f8ccfcd5e3f5
  content_type: application/pdf
  creator: asandaue
  date_created: 2021-08-16T07:48:03Z
  date_updated: 2021-08-16T07:48:03Z
  file_id: '9918'
  file_name: 2018_EvolutionLetters_Westram.pdf
  file_size: 764299
  relation: main_file
  success: 1
file_date_updated: 2021-08-16T07:48:03Z
has_accepted_license: '1'
intvolume: '         2'
isi: 1
issue: '4'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: 297-309
pmid: 1
publication: Evolution Letters
publication_identifier:
  eissn:
  - 2056-3744
  issn:
  - 2056-3744
publication_status: published
publisher: Wiley
quality_controlled: '1'
related_material:
  record:
  - id: '9930'
    relation: research_data
    status: public
status: public
title: 'Clines on the seashore: The genomic architecture underlying rapid divergence
  in the face of gene flow'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 2
year: '2018'
...
---
_id: '9929'
abstract:
- lang: eng
  text: 'The evolution of assortative mating is a key part of the speciation process.
    Stronger assortment, or greater divergence in mating traits, between species pairs
    with overlapping ranges is commonly observed, but possible causes of this pattern
    of reproductive character displacement are difficult to distinguish. We use a
    multidisciplinary approach to provide a rare example where it is possible to distinguish
    among hypotheses concerning the evolution of reproductive character displacement.
    We build on an earlier comparative analysis that illustrated a strong pattern
    of greater divergence in penis form between pairs of sister species with overlapping
    ranges than between allopatric sister-species pairs, in a large clade of marine
    gastropods (Littorinidae). We investigate both assortative mating and divergence
    in male genitalia in one of the sister-species pairs, discriminating among three
    contrasting processes each of which can generate a pattern of reproductive character
    displacement: reinforcement, reproductive interference and the Templeton effect.
    We demonstrate reproductive character displacement in assortative mating, but
    not in genital form between this pair of sister species and use demographic models
    to distinguish among the different processes. Our results support a model with
    no gene flow since secondary contact and thus favour reproductive interference
    as the cause of reproductive character displacement for mate choice, rather than
    reinforcement. High gene flow within species argues against the Templeton effect.
    Secondary contact appears to have had little impact on genital divergence.'
article_processing_charge: No
author:
- first_name: Johan
  full_name: Hollander, Johan
  last_name: Hollander
- first_name: Mauricio
  full_name: Montaño-Rendón, Mauricio
  last_name: Montaño-Rendón
- first_name: Giuseppe
  full_name: Bianco, Giuseppe
  last_name: Bianco
- first_name: Xi
  full_name: Yang, Xi
  last_name: Yang
- first_name: Anja M
  full_name: Westram, Anja M
  id: 3C147470-F248-11E8-B48F-1D18A9856A87
  last_name: Westram
  orcid: 0000-0003-1050-4969
- first_name: Ludovic
  full_name: Duvaux, Ludovic
  last_name: Duvaux
- first_name: David G.
  full_name: Reid, David G.
  last_name: Reid
- first_name: Roger K.
  full_name: Butlin, Roger K.
  last_name: Butlin
citation:
  ama: 'Hollander J, Montaño-Rendón M, Bianco G, et al. Data from: Are assortative
    mating and genital divergence driven by reinforcement? 2018. doi:<a href="https://doi.org/10.5061/dryad.51sd2p5">10.5061/dryad.51sd2p5</a>'
  apa: 'Hollander, J., Montaño-Rendón, M., Bianco, G., Yang, X., Westram, A. M., Duvaux,
    L., … Butlin, R. K. (2018). Data from: Are assortative mating and genital divergence
    driven by reinforcement? Dryad. <a href="https://doi.org/10.5061/dryad.51sd2p5">https://doi.org/10.5061/dryad.51sd2p5</a>'
  chicago: 'Hollander, Johan, Mauricio Montaño-Rendón, Giuseppe Bianco, Xi Yang, Anja
    M Westram, Ludovic Duvaux, David G. Reid, and Roger K. Butlin. “Data from: Are
    Assortative Mating and Genital Divergence Driven by Reinforcement?” Dryad, 2018.
    <a href="https://doi.org/10.5061/dryad.51sd2p5">https://doi.org/10.5061/dryad.51sd2p5</a>.'
  ieee: 'J. Hollander <i>et al.</i>, “Data from: Are assortative mating and genital
    divergence driven by reinforcement?” Dryad, 2018.'
  ista: 'Hollander J, Montaño-Rendón M, Bianco G, Yang X, Westram AM, Duvaux L, Reid
    DG, Butlin RK. 2018. Data from: Are assortative mating and genital divergence
    driven by reinforcement?, Dryad, <a href="https://doi.org/10.5061/dryad.51sd2p5">10.5061/dryad.51sd2p5</a>.'
  mla: 'Hollander, Johan, et al. <i>Data from: Are Assortative Mating and Genital
    Divergence Driven by Reinforcement?</i> Dryad, 2018, doi:<a href="https://doi.org/10.5061/dryad.51sd2p5">10.5061/dryad.51sd2p5</a>.'
  short: J. Hollander, M. Montaño-Rendón, G. Bianco, X. Yang, A.M. Westram, L. Duvaux,
    D.G. Reid, R.K. Butlin, (2018).
date_created: 2021-08-17T08:51:06Z
date_published: 2018-10-17T00:00:00Z
date_updated: 2023-09-19T15:08:53Z
day: '17'
department:
- _id: BeVi
doi: 10.5061/dryad.51sd2p5
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5061/dryad.51sd2p5
month: '10'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
  record:
  - id: '9915'
    relation: used_in_publication
    status: public
status: public
title: 'Data from: Are assortative mating and genital divergence driven by reinforcement?'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2018'
...
---
_id: '9930'
abstract:
- lang: eng
  text: Adaptive divergence and speciation may happen despite opposition by gene flow.
    Identifying the genomic basis underlying divergence with gene flow is a major
    task in evolutionary genomics. Most approaches (e.g. outlier scans) focus on genomic
    regions of high differentiation. However, not all genomic architectures potentially
    underlying divergence are expected to show extreme differentiation. Here, we develop
    an approach that combines hybrid zone analysis (i.e. focuses on spatial patterns
    of allele frequency change) with system-specific simulations to identify loci
    inconsistent with neutral evolution. We apply this to a genome-wide SNP set from
    an ideally-suited study organism, the intertidal snail Littorina saxatilis, which
    shows primary divergence between ecotypes associated with different shore habitats.
    We detect many SNPs with clinal patterns, most of which are consistent with neutrality.
    Among non-neutral SNPs, most are located within three large putative inversions
    differentiating ecotypes. Many non-neutral SNPs show relatively low levels of
    differentiation. We discuss potential reasons for this pattern, including loose
    linkage to selected variants, polygenic adaptation and a component of balancing
    selection within populations (which may be expected for inversions). Our work
    is in line with theory predicting a role for inversions in divergence, and emphasises
    that genomic regions contributing to divergence may not always be accessible with
    methods purely based on allele frequency differences. These conclusions call for
    approaches that take spatial patterns of allele frequency change into account
    in other systems.
article_processing_charge: No
author:
- first_name: Anja M
  full_name: Westram, Anja M
  id: 3C147470-F248-11E8-B48F-1D18A9856A87
  last_name: Westram
  orcid: 0000-0003-1050-4969
- first_name: Marina
  full_name: Rafajlović, Marina
  last_name: Rafajlović
- first_name: Pragya
  full_name: Chaube, Pragya
  last_name: Chaube
- first_name: Rui
  full_name: Faria, Rui
  last_name: Faria
- first_name: Tomas
  full_name: Larsson, Tomas
  last_name: Larsson
- first_name: Marina
  full_name: Panova, Marina
  last_name: Panova
- first_name: Mark
  full_name: Ravinet, Mark
  last_name: Ravinet
- first_name: Anders
  full_name: Blomberg, Anders
  last_name: Blomberg
- first_name: Bernhard
  full_name: Mehlig, Bernhard
  last_name: Mehlig
- first_name: Kerstin
  full_name: Johannesson, Kerstin
  last_name: Johannesson
- first_name: Roger
  full_name: Butlin, Roger
  last_name: Butlin
citation:
  ama: 'Westram AM, Rafajlović M, Chaube P, et al. Data from: Clines on the seashore:
    the genomic architecture underlying rapid divergence in the face of gene flow.
    2018. doi:<a href="https://doi.org/10.5061/dryad.bp25b65">10.5061/dryad.bp25b65</a>'
  apa: 'Westram, A. M., Rafajlović, M., Chaube, P., Faria, R., Larsson, T., Panova,
    M., … Butlin, R. (2018). Data from: Clines on the seashore: the genomic architecture
    underlying rapid divergence in the face of gene flow. Dryad. <a href="https://doi.org/10.5061/dryad.bp25b65">https://doi.org/10.5061/dryad.bp25b65</a>'
  chicago: 'Westram, Anja M, Marina Rafajlović, Pragya Chaube, Rui Faria, Tomas Larsson,
    Marina Panova, Mark Ravinet, et al. “Data from: Clines on the Seashore: The Genomic
    Architecture Underlying Rapid Divergence in the Face of Gene Flow.” Dryad, 2018.
    <a href="https://doi.org/10.5061/dryad.bp25b65">https://doi.org/10.5061/dryad.bp25b65</a>.'
  ieee: 'A. M. Westram <i>et al.</i>, “Data from: Clines on the seashore: the genomic
    architecture underlying rapid divergence in the face of gene flow.” Dryad, 2018.'
  ista: 'Westram AM, Rafajlović M, Chaube P, Faria R, Larsson T, Panova M, Ravinet
    M, Blomberg A, Mehlig B, Johannesson K, Butlin R. 2018. Data from: Clines on the
    seashore: the genomic architecture underlying rapid divergence in the face of
    gene flow, Dryad, <a href="https://doi.org/10.5061/dryad.bp25b65">10.5061/dryad.bp25b65</a>.'
  mla: 'Westram, Anja M., et al. <i>Data from: Clines on the Seashore: The Genomic
    Architecture Underlying Rapid Divergence in the Face of Gene Flow</i>. Dryad,
    2018, doi:<a href="https://doi.org/10.5061/dryad.bp25b65">10.5061/dryad.bp25b65</a>.'
  short: A.M. Westram, M. Rafajlović, P. Chaube, R. Faria, T. Larsson, M. Panova,
    M. Ravinet, A. Blomberg, B. Mehlig, K. Johannesson, R. Butlin, (2018).
date_created: 2021-08-17T08:58:47Z
date_published: 2018-07-23T00:00:00Z
date_updated: 2023-09-19T15:08:24Z
day: '23'
department:
- _id: BeVi
doi: 10.5061/dryad.bp25b65
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5061/dryad.bp25b65
month: '07'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
  record:
  - id: '9917'
    relation: used_in_publication
    status: public
status: public
title: 'Data from: Clines on the seashore: the genomic architecture underlying rapid
  divergence in the face of gene flow'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2018'
...
---
_id: '10864'
abstract:
- lang: eng
  text: We prove that every congruence distributive variety has directed Jónsson terms,
    and every congruence modular variety has directed Gumm terms. The directed terms
    we construct witness every case of absorption witnessed by the original Jónsson
    or Gumm terms. This result is equivalent to a pair of claims about absorption
    for admissible preorders in congruence distributive and congruence modular varieties,
    respectively. For finite algebras, these absorption theorems have already seen
    significant applications, but until now, it was not clear if the theorems hold
    for general algebras as well. Our method also yields a novel proof of a result
    by P. Lipparini about the existence of a chain of terms (which we call Pixley
    terms) in varieties that are at the same time congruence distributive and k-permutable
    for some k.
acknowledgement: The second author was supported by National Science Center grant
  DEC-2011-/01/B/ST6/01006.
article_processing_charge: No
arxiv: 1
author:
- first_name: Alexandr
  full_name: Kazda, Alexandr
  id: 3B32BAA8-F248-11E8-B48F-1D18A9856A87
  last_name: Kazda
- first_name: Marcin
  full_name: Kozik, Marcin
  last_name: Kozik
- first_name: Ralph
  full_name: McKenzie, Ralph
  last_name: McKenzie
- first_name: Matthew
  full_name: Moore, Matthew
  last_name: Moore
citation:
  ama: 'Kazda A, Kozik M, McKenzie R, Moore M. Absorption and directed Jónsson terms.
    In: Czelakowski J, ed. <i>Don Pigozzi on Abstract Algebraic Logic, Universal Algebra,
    and Computer Science</i>. Vol 16. OCTR. Cham: Springer Nature; 2018:203-220. doi:<a
    href="https://doi.org/10.1007/978-3-319-74772-9_7">10.1007/978-3-319-74772-9_7</a>'
  apa: 'Kazda, A., Kozik, M., McKenzie, R., &#38; Moore, M. (2018). Absorption and
    directed Jónsson terms. In J. Czelakowski (Ed.), <i>Don Pigozzi on Abstract Algebraic
    Logic, Universal Algebra, and Computer Science</i> (Vol. 16, pp. 203–220). Cham:
    Springer Nature. <a href="https://doi.org/10.1007/978-3-319-74772-9_7">https://doi.org/10.1007/978-3-319-74772-9_7</a>'
  chicago: 'Kazda, Alexandr, Marcin Kozik, Ralph McKenzie, and Matthew Moore. “Absorption
    and Directed Jónsson Terms.” In <i>Don Pigozzi on Abstract Algebraic Logic, Universal
    Algebra, and Computer Science</i>, edited by J Czelakowski, 16:203–20. OCTR. Cham:
    Springer Nature, 2018. <a href="https://doi.org/10.1007/978-3-319-74772-9_7">https://doi.org/10.1007/978-3-319-74772-9_7</a>.'
  ieee: 'A. Kazda, M. Kozik, R. McKenzie, and M. Moore, “Absorption and directed Jónsson
    terms,” in <i>Don Pigozzi on Abstract Algebraic Logic, Universal Algebra, and
    Computer Science</i>, vol. 16, J. Czelakowski, Ed. Cham: Springer Nature, 2018,
    pp. 203–220.'
  ista: 'Kazda A, Kozik M, McKenzie R, Moore M. 2018.Absorption and directed Jónsson
    terms. In: Don Pigozzi on Abstract Algebraic Logic, Universal Algebra, and Computer
    Science. vol. 16, 203–220.'
  mla: Kazda, Alexandr, et al. “Absorption and Directed Jónsson Terms.” <i>Don Pigozzi
    on Abstract Algebraic Logic, Universal Algebra, and Computer Science</i>, edited
    by J Czelakowski, vol. 16, Springer Nature, 2018, pp. 203–20, doi:<a href="https://doi.org/10.1007/978-3-319-74772-9_7">10.1007/978-3-319-74772-9_7</a>.
  short: A. Kazda, M. Kozik, R. McKenzie, M. Moore, in:, J. Czelakowski (Ed.), Don
    Pigozzi on Abstract Algebraic Logic, Universal Algebra, and Computer Science,
    Springer Nature, Cham, 2018, pp. 203–220.
date_created: 2022-03-18T10:30:32Z
date_published: 2018-03-21T00:00:00Z
date_updated: 2023-09-05T15:37:18Z
day: '21'
department:
- _id: VlKo
doi: 10.1007/978-3-319-74772-9_7
editor:
- first_name: J
  full_name: Czelakowski, J
  last_name: Czelakowski
external_id:
  arxiv:
  - '1502.01072'
intvolume: '        16'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1502.01072
month: '03'
oa: 1
oa_version: Preprint
page: 203-220
place: Cham
publication: Don Pigozzi on Abstract Algebraic Logic, Universal Algebra, and Computer
  Science
publication_identifier:
  eisbn:
  - '9783319747729'
  eissn:
  - 2211-2766
  isbn:
  - '9783319747712'
  issn:
  - 2211-2758
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
series_title: OCTR
status: public
title: Absorption and directed Jónsson terms
type: book_chapter
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 16
year: '2018'
...
---
_id: '10880'
abstract:
- lang: eng
  text: Acquisition of evolutionary novelties is a fundamental process for adapting
    to the external environment and invading new niches and results in the diversification
    of life, which we can see in the world today. How such novel phenotypic traits
    are acquired in the course of evolution and are built up in developing embryos
    has been a central question in biology. Whole-genome duplication (WGD) is a process
    of genome doubling that supplies raw genetic materials and increases genome complexity.
    Recently, it has been gradually revealed that WGD and subsequent fate changes
    of duplicated genes can facilitate phenotypic evolution. Here, we review the current
    understanding of the relationship between WGD and the acquisition of evolutionary
    novelties. We show some examples of this link and discuss how WGD and subsequent
    duplicated genes can facilitate phenotypic evolution as well as when such genomic
    doubling can be advantageous for adaptation.
acknowledgement: This work was supported by JSPS overseas research fellowships (Y.M.)
  and SENSHIN Medical Research Foundation (K.K.T.).
article_processing_charge: No
article_type: original
author:
- first_name: Moriyama
  full_name: Yuuta, Moriyama
  id: 4968E7C8-F248-11E8-B48F-1D18A9856A87
  last_name: Yuuta
  orcid: 0000-0002-2853-8051
- first_name: Kazuko
  full_name: Koshiba-Takeuchi, Kazuko
  last_name: Koshiba-Takeuchi
citation:
  ama: Yuuta M, Koshiba-Takeuchi K. Significance of whole-genome duplications on the
    emergence of evolutionary novelties. <i>Briefings in Functional Genomics</i>.
    2018;17(5):329-338. doi:<a href="https://doi.org/10.1093/bfgp/ely007">10.1093/bfgp/ely007</a>
  apa: Yuuta, M., &#38; Koshiba-Takeuchi, K. (2018). Significance of whole-genome
    duplications on the emergence of evolutionary novelties. <i>Briefings in Functional
    Genomics</i>. Oxford University Press. <a href="https://doi.org/10.1093/bfgp/ely007">https://doi.org/10.1093/bfgp/ely007</a>
  chicago: Yuuta, Moriyama, and Kazuko Koshiba-Takeuchi. “Significance of Whole-Genome
    Duplications on the Emergence of Evolutionary Novelties.” <i>Briefings in Functional
    Genomics</i>. Oxford University Press, 2018. <a href="https://doi.org/10.1093/bfgp/ely007">https://doi.org/10.1093/bfgp/ely007</a>.
  ieee: M. Yuuta and K. Koshiba-Takeuchi, “Significance of whole-genome duplications
    on the emergence of evolutionary novelties,” <i>Briefings in Functional Genomics</i>,
    vol. 17, no. 5. Oxford University Press, pp. 329–338, 2018.
  ista: Yuuta M, Koshiba-Takeuchi K. 2018. Significance of whole-genome duplications
    on the emergence of evolutionary novelties. Briefings in Functional Genomics.
    17(5), 329–338.
  mla: Yuuta, Moriyama, and Kazuko Koshiba-Takeuchi. “Significance of Whole-Genome
    Duplications on the Emergence of Evolutionary Novelties.” <i>Briefings in Functional
    Genomics</i>, vol. 17, no. 5, Oxford University Press, 2018, pp. 329–38, doi:<a
    href="https://doi.org/10.1093/bfgp/ely007">10.1093/bfgp/ely007</a>.
  short: M. Yuuta, K. Koshiba-Takeuchi, Briefings in Functional Genomics 17 (2018)
    329–338.
date_created: 2022-03-18T12:40:35Z
date_published: 2018-09-01T00:00:00Z
date_updated: 2023-09-19T15:11:22Z
day: '01'
department:
- _id: CaHe
doi: 10.1093/bfgp/ely007
external_id:
  isi:
  - '000456054400004'
  pmid:
  - '29579140'
intvolume: '        17'
isi: 1
issue: '5'
keyword:
- Genetics
- Molecular Biology
- Biochemistry
- General Medicine
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1093/bfgp/ely007
month: '09'
oa: 1
oa_version: Published Version
page: 329-338
pmid: 1
publication: Briefings in Functional Genomics
publication_identifier:
  eissn:
  - 2041-2657
  issn:
  - 2041-2649
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Significance of whole-genome duplications on the emergence of evolutionary
  novelties
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 17
year: '2018'
...
---
_id: '10881'
abstract:
- lang: eng
  text: Strigolactones (SLs) are a relatively recent addition to the list of plant
    hormones that control different aspects of plant development. SL signalling is
    perceived by an α/β hydrolase, DWARF 14 (D14). A close homolog of D14, KARRIKIN
    INSENSTIVE2 (KAI2), is involved in perception of an uncharacterized molecule called
    karrikin (KAR). Recent studies in Arabidopsis identified the SUPPRESSOR OF MAX2
    1 (SMAX1) and SMAX1-LIKE 7 (SMXL7) to be potential SCF–MAX2 complex-mediated proteasome
    targets of KAI2 and D14, respectively. Genetic studies on SMXL7 and SMAX1 demonstrated
    distinct developmental roles for each, but very little is known about these repressors
    in terms of their sequence features. In this study, we performed an extensive
    comparative analysis of SMXLs and determined their phylogenetic and evolutionary
    history in the plant lineage. Our results show that SMXL family members can be
    sub-divided into four distinct phylogenetic clades/classes, with an ancient SMAX1.
    Further, we identified the clade-specific motifs that have evolved and that might
    act as determinants of SL-KAR signalling specificity. These specificities resulted
    from functional diversities among the clades. Our results suggest that a gradual
    co-evolution of SMXL members with their upstream receptors D14/KAI2 provided an
    increased specificity to both the SL perception and response in land plants.
acknowledgement: "This project received funding from the European Union’s Horizon
  2020 research and innovation programme under the Marie Skłodowska-Curie Actions
  and it is co-financed by the South Moravian Region under grant agreement No. 665860
  (SS). Access to computing and storage facilities owned by parties and projects contributing
  to the national grid infrastructure, MetaCentrum, provided under the program ‘Projects
  of Large Infrastructure for Research, Development, and Innovations’ (LM2010005)
  was greatly appreciated (RSV). The project was funded by The Ministry of Education,
  Youth and Sports/MES of the Czech Republic under the project CEITEC 2020 (LQ1601)
  (TN, TRM). JF was supported by the European Research Council (project ERC-2011-StG
  20101109-PSDP) and the Czech Science Foundation GAČR (GA13-40637S). We thank Dr
  Kamel Chibani for active discussions on the evolutionary analysis and Nandan Mysore
  Vardarajan for his critical comments on the manuscript. This article reflects\r\nonly
  the authors’ views, and the EU is not responsible for any use that may be made of
  the information it contains. "
article_processing_charge: No
article_type: original
author:
- first_name: Taraka Ramji
  full_name: Moturu, Taraka Ramji
  last_name: Moturu
- first_name: Sravankumar
  full_name: Thula, Sravankumar
  last_name: Thula
- first_name: Ravi Kumar
  full_name: Singh, Ravi Kumar
  last_name: Singh
- first_name: Tomasz
  full_name: Nodzyński, Tomasz
  last_name: Nodzyński
- first_name: Radka Svobodová
  full_name: Vařeková, Radka Svobodová
  last_name: Vařeková
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Sibu
  full_name: Simon, Sibu
  last_name: Simon
citation:
  ama: Moturu TR, Thula S, Singh RK, et al. Molecular evolution and diversification
    of the SMXL gene family. <i>Journal of Experimental Botany</i>. 2018;69(9):2367-2378.
    doi:<a href="https://doi.org/10.1093/jxb/ery097">10.1093/jxb/ery097</a>
  apa: Moturu, T. R., Thula, S., Singh, R. K., Nodzyński, T., Vařeková, R. S., Friml,
    J., &#38; Simon, S. (2018). Molecular evolution and diversification of the SMXL
    gene family. <i>Journal of Experimental Botany</i>. Oxford University Press. <a
    href="https://doi.org/10.1093/jxb/ery097">https://doi.org/10.1093/jxb/ery097</a>
  chicago: Moturu, Taraka Ramji, Sravankumar Thula, Ravi Kumar Singh, Tomasz Nodzyński,
    Radka Svobodová Vařeková, Jiří Friml, and Sibu Simon. “Molecular Evolution and
    Diversification of the SMXL Gene Family.” <i>Journal of Experimental Botany</i>.
    Oxford University Press, 2018. <a href="https://doi.org/10.1093/jxb/ery097">https://doi.org/10.1093/jxb/ery097</a>.
  ieee: T. R. Moturu <i>et al.</i>, “Molecular evolution and diversification of the
    SMXL gene family,” <i>Journal of Experimental Botany</i>, vol. 69, no. 9. Oxford
    University Press, pp. 2367–2378, 2018.
  ista: Moturu TR, Thula S, Singh RK, Nodzyński T, Vařeková RS, Friml J, Simon S.
    2018. Molecular evolution and diversification of the SMXL gene family. Journal
    of Experimental Botany. 69(9), 2367–2378.
  mla: Moturu, Taraka Ramji, et al. “Molecular Evolution and Diversification of the
    SMXL Gene Family.” <i>Journal of Experimental Botany</i>, vol. 69, no. 9, Oxford
    University Press, 2018, pp. 2367–78, doi:<a href="https://doi.org/10.1093/jxb/ery097">10.1093/jxb/ery097</a>.
  short: T.R. Moturu, S. Thula, R.K. Singh, T. Nodzyński, R.S. Vařeková, J. Friml,
    S. Simon, Journal of Experimental Botany 69 (2018) 2367–2378.
date_created: 2022-03-18T12:43:22Z
date_published: 2018-04-13T00:00:00Z
date_updated: 2025-05-07T11:12:33Z
day: '13'
department:
- _id: JiFr
doi: 10.1093/jxb/ery097
ec_funded: 1
external_id:
  isi:
  - '000430727000016'
  pmid:
  - '29538714'
intvolume: '        69'
isi: 1
issue: '9'
keyword:
- Plant Science
- Physiology
language:
- iso: eng
month: '04'
oa_version: None
page: 2367-2378
pmid: 1
project:
- _id: 25716A02-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '282300'
  name: Polarity and subcellular dynamics in plants
publication: Journal of Experimental Botany
publication_identifier:
  eissn:
  - 1460-2431
  issn:
  - 0022-0957
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Molecular evolution and diversification of the SMXL gene family
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 69
year: '2018'
...
---
_id: '10882'
abstract:
- lang: eng
  text: 'We introduce Intelligent Annotation Dialogs for bounding box annotation.
    We train an agent to automatically choose a sequence of actions for a human annotator
    to produce a bounding box in a minimal amount of time. Specifically, we consider
    two actions: box verification [34], where the annotator verifies a box generated
    by an object detector, and manual box drawing. We explore two kinds of agents,
    one based on predicting the probability that a box will be positively verified,
    and the other based on reinforcement learning. We demonstrate that (1) our agents
    are able to learn efficient annotation strategies in several scenarios, automatically
    adapting to the image difficulty, the desired quality of the boxes, and the detector
    strength; (2) in all scenarios the resulting annotation dialogs speed up annotation
    compared to manual box drawing alone and box verification alone, while also outperforming
    any fixed combination of verification and drawing in most scenarios; (3) in a
    realistic scenario where the detector is iteratively re-trained, our agents evolve
    a series of strategies that reflect the shifting trade-off between verification
    and drawing as the detector grows stronger.'
article_processing_charge: No
arxiv: 1
author:
- first_name: Jasper
  full_name: Uijlings, Jasper
  last_name: Uijlings
- first_name: Ksenia
  full_name: Konyushkova, Ksenia
  last_name: Konyushkova
- first_name: Christoph
  full_name: Lampert, Christoph
  id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
  last_name: Lampert
  orcid: 0000-0001-8622-7887
- first_name: Vittorio
  full_name: Ferrari, Vittorio
  last_name: Ferrari
citation:
  ama: 'Uijlings J, Konyushkova K, Lampert C, Ferrari V. Learning intelligent dialogs
    for bounding box annotation. In: <i>2018 IEEE/CVF Conference on Computer Vision
    and Pattern Recognition</i>. IEEE; 2018:9175-9184. doi:<a href="https://doi.org/10.1109/cvpr.2018.00956">10.1109/cvpr.2018.00956</a>'
  apa: 'Uijlings, J., Konyushkova, K., Lampert, C., &#38; Ferrari, V. (2018). Learning
    intelligent dialogs for bounding box annotation. In <i>2018 IEEE/CVF Conference
    on Computer Vision and Pattern Recognition</i> (pp. 9175–9184). Salt Lake City,
    UT, United States: IEEE. <a href="https://doi.org/10.1109/cvpr.2018.00956">https://doi.org/10.1109/cvpr.2018.00956</a>'
  chicago: Uijlings, Jasper, Ksenia Konyushkova, Christoph Lampert, and Vittorio Ferrari.
    “Learning Intelligent Dialogs for Bounding Box Annotation.” In <i>2018 IEEE/CVF
    Conference on Computer Vision and Pattern Recognition</i>, 9175–84. IEEE, 2018.
    <a href="https://doi.org/10.1109/cvpr.2018.00956">https://doi.org/10.1109/cvpr.2018.00956</a>.
  ieee: J. Uijlings, K. Konyushkova, C. Lampert, and V. Ferrari, “Learning intelligent
    dialogs for bounding box annotation,” in <i>2018 IEEE/CVF Conference on Computer
    Vision and Pattern Recognition</i>, Salt Lake City, UT, United States, 2018, pp.
    9175–9184.
  ista: 'Uijlings J, Konyushkova K, Lampert C, Ferrari V. 2018. Learning intelligent
    dialogs for bounding box annotation. 2018 IEEE/CVF Conference on Computer Vision
    and Pattern Recognition. CVF: Conference on Computer Vision and Pattern Recognition,
    9175–9184.'
  mla: Uijlings, Jasper, et al. “Learning Intelligent Dialogs for Bounding Box Annotation.”
    <i>2018 IEEE/CVF Conference on Computer Vision and Pattern Recognition</i>, IEEE,
    2018, pp. 9175–84, doi:<a href="https://doi.org/10.1109/cvpr.2018.00956">10.1109/cvpr.2018.00956</a>.
  short: J. Uijlings, K. Konyushkova, C. Lampert, V. Ferrari, in:, 2018 IEEE/CVF Conference
    on Computer Vision and Pattern Recognition, IEEE, 2018, pp. 9175–9184.
conference:
  end_date: 2018-06-23
  location: Salt Lake City, UT, United States
  name: 'CVF: Conference on Computer Vision and Pattern Recognition'
  start_date: 2018-06-18
date_created: 2022-03-18T12:45:09Z
date_published: 2018-12-17T00:00:00Z
date_updated: 2023-09-19T15:11:49Z
day: '17'
department:
- _id: ChLa
doi: 10.1109/cvpr.2018.00956
external_id:
  arxiv:
  - '1712.08087'
  isi:
  - '000457843609036'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: ' https://doi.org/10.48550/arXiv.1712.08087'
month: '12'
oa: 1
oa_version: Preprint
page: 9175-9184
publication: 2018 IEEE/CVF Conference on Computer Vision and Pattern Recognition
publication_identifier:
  eissn:
  - 2575-7075
  isbn:
  - '9781538664209'
publication_status: published
publisher: IEEE
quality_controlled: '1'
scopus_import: '1'
status: public
title: Learning intelligent dialogs for bounding box annotation
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2018'
...
---
_id: '10883'
abstract:
- lang: eng
  text: 'Solving parity games, which are equivalent to modal μ-calculus model checking,
    is a central algorithmic problem in formal methods, with applications in reactive
    synthesis, program repair, verification of branching-time properties, etc. Besides
    the standard compu- tation model with the explicit representation of games, another
    important theoretical model of computation is that of set-based symbolic algorithms.
    Set-based symbolic algorithms use basic set operations and one-step predecessor
    operations on the implicit description of games, rather than the explicit representation.
    The significance of symbolic algorithms is that they provide scalable algorithms
    for large finite-state systems, as well as for infinite-state systems with finite
    quotient. Consider parity games on graphs with n vertices and parity conditions
    with d priorities. While there is a rich literature of explicit algorithms for
    parity games, the main results for set-based symbolic algorithms are as follows:
    (a) the basic algorithm that requires O(nd) symbolic operations and O(d) symbolic
    space; and (b) an improved algorithm that requires O(nd/3+1) symbolic operations
    and O(n) symbolic space. In this work, our contributions are as follows: (1) We
    present a black-box set-based symbolic algorithm based on the explicit progress
    measure algorithm. Two important consequences of our algorithm are as follows:
    (a) a set-based symbolic algorithm for parity games that requires quasi-polynomially
    many symbolic operations and O(n) symbolic space; and (b) any future improvement
    in progress measure based explicit algorithms immediately imply an efficiency
    improvement in our set-based symbolic algorithm for parity games. (2) We present
    a set-based symbolic algorithm that requires quasi-polynomially many symbolic
    operations and O(d · log n) symbolic space. Moreover, for the important special
    case of d ≤ log n, our algorithm requires only polynomially many symbolic operations
    and poly-logarithmic symbolic space.'
acknowledgement: 'A. S. is fully supported by the Vienna Science and Technology Fund
  (WWTF) through project ICT15-003. K.C. is supported by the Austrian Science Fund
  (FWF) NFN Grant No S11407-N23 (RiSE/SHiNE) and an ERC Starting grant (279307: Graph
  Games). For M.H the research leading to these results has received funding from
  the European Research Council under the European Union’s Seventh Framework Programme
  (FP/2007-2013) /ERC Grant Agreement no. 340506.'
alternative_title:
- EPiC Series in Computing
article_processing_charge: No
arxiv: 1
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Wolfgang
  full_name: Dvořák, Wolfgang
  last_name: Dvořák
- first_name: Monika H
  full_name: Henzinger, Monika H
  id: 540c9bbd-f2de-11ec-812d-d04a5be85630
  last_name: Henzinger
  orcid: 0000-0002-5008-6530
- first_name: Alexander
  full_name: Svozil, Alexander
  last_name: Svozil
citation:
  ama: 'Chatterjee K, Dvořák W, Henzinger MH, Svozil A. Quasipolynomial set-based
    symbolic algorithms for parity games. In: <i>22nd International Conference on
    Logic for Programming, Artificial Intelligence and Reasoning</i>. Vol 57. EasyChair;
    2018:233-253. doi:<a href="https://doi.org/10.29007/5z5k">10.29007/5z5k</a>'
  apa: 'Chatterjee, K., Dvořák, W., Henzinger, M. H., &#38; Svozil, A. (2018). Quasipolynomial
    set-based symbolic algorithms for parity games. In <i>22nd International Conference
    on Logic for Programming, Artificial Intelligence and Reasoning</i> (Vol. 57,
    pp. 233–253). Awassa, Ethiopia: EasyChair. <a href="https://doi.org/10.29007/5z5k">https://doi.org/10.29007/5z5k</a>'
  chicago: Chatterjee, Krishnendu, Wolfgang Dvořák, Monika H Henzinger, and Alexander
    Svozil. “Quasipolynomial Set-Based Symbolic Algorithms for Parity Games.” In <i>22nd
    International Conference on Logic for Programming, Artificial Intelligence and
    Reasoning</i>, 57:233–53. EasyChair, 2018. <a href="https://doi.org/10.29007/5z5k">https://doi.org/10.29007/5z5k</a>.
  ieee: K. Chatterjee, W. Dvořák, M. H. Henzinger, and A. Svozil, “Quasipolynomial
    set-based symbolic algorithms for parity games,” in <i>22nd International Conference
    on Logic for Programming, Artificial Intelligence and Reasoning</i>, Awassa, Ethiopia,
    2018, vol. 57, pp. 233–253.
  ista: 'Chatterjee K, Dvořák W, Henzinger MH, Svozil A. 2018. Quasipolynomial set-based
    symbolic algorithms for parity games. 22nd International Conference on Logic for
    Programming, Artificial Intelligence and Reasoning. LPAR: Conference on Logic
    for Programming, Artificial Intelligence and Reasoning, EPiC Series in Computing,
    vol. 57, 233–253.'
  mla: Chatterjee, Krishnendu, et al. “Quasipolynomial Set-Based Symbolic Algorithms
    for Parity Games.” <i>22nd International Conference on Logic for Programming,
    Artificial Intelligence and Reasoning</i>, vol. 57, EasyChair, 2018, pp. 233–53,
    doi:<a href="https://doi.org/10.29007/5z5k">10.29007/5z5k</a>.
  short: K. Chatterjee, W. Dvořák, M.H. Henzinger, A. Svozil, in:, 22nd International
    Conference on Logic for Programming, Artificial Intelligence and Reasoning, EasyChair,
    2018, pp. 233–253.
conference:
  end_date: 2018-11-21
  location: Awassa, Ethiopia
  name: 'LPAR: Conference on Logic for Programming, Artificial Intelligence and Reasoning'
  start_date: 2018-11-17
date_created: 2022-03-18T12:46:32Z
date_published: 2018-10-23T00:00:00Z
date_updated: 2022-07-29T09:24:31Z
day: '23'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.29007/5z5k
ec_funded: 1
external_id:
  arxiv:
  - '1909.04983'
file:
- access_level: open_access
  checksum: 1229aa8640bd6db610c85decf2265480
  content_type: application/pdf
  creator: dernst
  date_created: 2022-05-17T07:51:08Z
  date_updated: 2022-05-17T07:51:08Z
  file_id: '11392'
  file_name: 2018_EPiCs_Chatterjee.pdf
  file_size: 720893
  relation: main_file
  success: 1
file_date_updated: 2022-05-17T07:51:08Z
has_accepted_license: '1'
intvolume: '        57'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
page: 233-253
project:
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S11407
  name: Game Theory
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '279307'
  name: 'Quantitative Graph Games: Theory and Applications'
publication: 22nd International Conference on Logic for Programming, Artificial Intelligence
  and Reasoning
publication_identifier:
  issn:
  - 2398-7340
publication_status: published
publisher: EasyChair
quality_controlled: '1'
scopus_import: '1'
status: public
title: Quasipolynomial set-based symbolic algorithms for parity games
type: conference
user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd
volume: 57
year: '2018'
...
---
_id: '1092'
abstract:
- lang: eng
  text: 'A graphical model encodes conditional independence relations via the Markov
    properties. For an undirected graph these conditional independence relations can
    be represented by a simple polytope known as the graph associahedron, which can
    be constructed as a Minkowski sum of standard simplices. We show that there is
    an analogous polytope for conditional independence relations coming from a regular
    Gaussian model, and it can be defined using multiinformation or relative entropy.
    For directed acyclic graphical models we give a construction of this polytope
    as a Minkowski sum of matroid polytopes. Finally, we apply this geometric insight
    to construct a new ordering-based search algorithm for causal inference via directed
    acyclic graphical models. '
author:
- first_name: Fatemeh
  full_name: Mohammadi, Fatemeh
  id: 2C29581E-F248-11E8-B48F-1D18A9856A87
  last_name: Mohammadi
- first_name: Caroline
  full_name: Uhler, Caroline
  id: 49ADD78E-F248-11E8-B48F-1D18A9856A87
  last_name: Uhler
  orcid: 0000-0002-7008-0216
- first_name: Charles
  full_name: Wang, Charles
  last_name: Wang
- first_name: Josephine
  full_name: Yu, Josephine
  last_name: Yu
citation:
  ama: Mohammadi F, Uhler C, Wang C, Yu J. Generalized permutohedra from probabilistic
    graphical models. <i>SIAM Journal on Discrete Mathematics</i>. 2018;32(1):64-93.
    doi:<a href="https://doi.org/10.1137/16M107894X">10.1137/16M107894X</a>
  apa: Mohammadi, F., Uhler, C., Wang, C., &#38; Yu, J. (2018). Generalized permutohedra
    from probabilistic graphical models. <i>SIAM Journal on Discrete Mathematics</i>.
    SIAM. <a href="https://doi.org/10.1137/16M107894X">https://doi.org/10.1137/16M107894X</a>
  chicago: Mohammadi, Fatemeh, Caroline Uhler, Charles Wang, and Josephine Yu. “Generalized
    Permutohedra from Probabilistic Graphical Models.” <i>SIAM Journal on Discrete
    Mathematics</i>. SIAM, 2018. <a href="https://doi.org/10.1137/16M107894X">https://doi.org/10.1137/16M107894X</a>.
  ieee: F. Mohammadi, C. Uhler, C. Wang, and J. Yu, “Generalized permutohedra from
    probabilistic graphical models,” <i>SIAM Journal on Discrete Mathematics</i>,
    vol. 32, no. 1. SIAM, pp. 64–93, 2018.
  ista: Mohammadi F, Uhler C, Wang C, Yu J. 2018. Generalized permutohedra from probabilistic
    graphical models. SIAM Journal on Discrete Mathematics. 32(1), 64–93.
  mla: Mohammadi, Fatemeh, et al. “Generalized Permutohedra from Probabilistic Graphical
    Models.” <i>SIAM Journal on Discrete Mathematics</i>, vol. 32, no. 1, SIAM, 2018,
    pp. 64–93, doi:<a href="https://doi.org/10.1137/16M107894X">10.1137/16M107894X</a>.
  short: F. Mohammadi, C. Uhler, C. Wang, J. Yu, SIAM Journal on Discrete Mathematics
    32 (2018) 64–93.
date_created: 2018-12-11T11:50:06Z
date_published: 2018-01-01T00:00:00Z
date_updated: 2021-01-12T06:48:13Z
day: '01'
doi: 10.1137/16M107894X
extern: '1'
intvolume: '        32'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1606.01814
month: '01'
oa: 1
oa_version: Preprint
page: 64-93
publication: SIAM Journal on Discrete Mathematics
publication_status: published
publisher: SIAM
publist_id: '6284'
quality_controlled: '1'
status: public
title: Generalized permutohedra from probabilistic graphical models
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 32
year: '2018'
...
---
_id: '11'
abstract:
- lang: eng
  text: We report on a novel strategy to derive mean-field limits of quantum mechanical
    systems in which a large number of particles weakly couple to a second-quantized
    radiation field. The technique combines the method of counting and the coherent
    state approach to study the growth of the correlations among the particles and
    in the radiation field. As an instructional example, we derive the Schrödinger–Klein–Gordon
    system of equations from the Nelson model with ultraviolet cutoff and possibly
    massless scalar field. In particular, we prove the convergence of the reduced
    density matrices (of the nonrelativistic particles and the field bosons) associated
    with the exact time evolution to the projectors onto the solutions of the Schrödinger–Klein–Gordon
    equations in trace norm. Furthermore, we derive explicit bounds on the rate of
    convergence of the one-particle reduced density matrix of the nonrelativistic
    particles in Sobolev norm.
arxiv: 1
author:
- first_name: Nikolai K
  full_name: Leopold, Nikolai K
  id: 4BC40BEC-F248-11E8-B48F-1D18A9856A87
  last_name: Leopold
  orcid: 0000-0002-0495-6822
- first_name: Peter
  full_name: Pickl, Peter
  last_name: Pickl
citation:
  ama: 'Leopold NK, Pickl P. Mean-field limits of particles in interaction with quantised
    radiation fields. In: Vol 270. Springer; 2018:185-214. doi:<a href="https://doi.org/10.1007/978-3-030-01602-9_9">10.1007/978-3-030-01602-9_9</a>'
  apa: 'Leopold, N. K., &#38; Pickl, P. (2018). Mean-field limits of particles in
    interaction with quantised radiation fields (Vol. 270, pp. 185–214). Presented
    at the MaLiQS: Macroscopic Limits of Quantum Systems, Munich, Germany: Springer.
    <a href="https://doi.org/10.1007/978-3-030-01602-9_9">https://doi.org/10.1007/978-3-030-01602-9_9</a>'
  chicago: Leopold, Nikolai K, and Peter Pickl. “Mean-Field Limits of Particles in
    Interaction with Quantised Radiation Fields,” 270:185–214. Springer, 2018. <a
    href="https://doi.org/10.1007/978-3-030-01602-9_9">https://doi.org/10.1007/978-3-030-01602-9_9</a>.
  ieee: 'N. K. Leopold and P. Pickl, “Mean-field limits of particles in interaction
    with quantised radiation fields,” presented at the MaLiQS: Macroscopic Limits
    of Quantum Systems, Munich, Germany, 2018, vol. 270, pp. 185–214.'
  ista: 'Leopold NK, Pickl P. 2018. Mean-field limits of particles in interaction
    with quantised radiation fields. MaLiQS: Macroscopic Limits of Quantum Systems
    vol. 270, 185–214.'
  mla: Leopold, Nikolai K., and Peter Pickl. <i>Mean-Field Limits of Particles in
    Interaction with Quantised Radiation Fields</i>. Vol. 270, Springer, 2018, pp.
    185–214, doi:<a href="https://doi.org/10.1007/978-3-030-01602-9_9">10.1007/978-3-030-01602-9_9</a>.
  short: N.K. Leopold, P. Pickl, in:, Springer, 2018, pp. 185–214.
conference:
  end_date: 2017-04-01
  location: Munich, Germany
  name: 'MaLiQS: Macroscopic Limits of Quantum Systems'
  start_date: 2017-03-30
date_created: 2018-12-11T11:44:08Z
date_published: 2018-10-27T00:00:00Z
date_updated: 2021-01-12T06:48:16Z
day: '27'
department:
- _id: RoSe
doi: 10.1007/978-3-030-01602-9_9
ec_funded: 1
external_id:
  arxiv:
  - '1806.10843'
intvolume: '       270'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1806.10843
month: '10'
oa: 1
oa_version: Preprint
page: 185 - 214
project:
- _id: 25C6DC12-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '694227'
  name: Analysis of quantum many-body systems
publication_status: published
publisher: Springer
publist_id: '8045'
quality_controlled: '1'
scopus_import: 1
status: public
title: Mean-field limits of particles in interaction with quantised radiation fields
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 270
year: '2018'
...
---
_id: '11063'
abstract:
- lang: eng
  text: The total number of nuclear pore complexes (NPCs) per nucleus varies greatly
    between different cell types and is known to change during cell differentiation
    and cell transformation. However, the underlying mechanisms that control how many
    nuclear transport channels are assembled into a given nuclear envelope remain
    unclear. Here, we report that depletion of the NPC basket protein Tpr, but not
    Nup153, dramatically increases the total NPC number in various cell types. This
    negative regulation of Tpr occurs via a phosphorylation cascade of extracellular
    signal-regulated kinase (ERK), the central kinase of the mitogen-activated protein
    kinase (MAPK) pathway. Tpr serves as a scaffold for ERK to phosphorylate the nucleoporin
    (Nup) Nup153, which is critical for early stages of NPC biogenesis. Our results
    reveal a critical role of the Nup Tpr in coordinating signal transduction pathways
    during cell proliferation and the dynamic organization of the nucleus.
article_processing_charge: No
article_type: original
author:
- first_name: Asako
  full_name: McCloskey, Asako
  last_name: McCloskey
- first_name: Arkaitz
  full_name: Ibarra, Arkaitz
  last_name: Ibarra
- first_name: Martin W
  full_name: HETZER, Martin W
  id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
  last_name: HETZER
  orcid: 0000-0002-2111-992X
citation:
  ama: McCloskey A, Ibarra A, Hetzer M. Tpr regulates the total number of nuclear
    pore complexes per cell nucleus. <i>Genes &#38; Development</i>. 2018;32(19-20):1321-1331.
    doi:<a href="https://doi.org/10.1101/gad.315523.118">10.1101/gad.315523.118</a>
  apa: McCloskey, A., Ibarra, A., &#38; Hetzer, M. (2018). Tpr regulates the total
    number of nuclear pore complexes per cell nucleus. <i>Genes &#38; Development</i>.
    Cold Spring Harbor Laboratory. <a href="https://doi.org/10.1101/gad.315523.118">https://doi.org/10.1101/gad.315523.118</a>
  chicago: McCloskey, Asako, Arkaitz Ibarra, and Martin Hetzer. “Tpr Regulates the
    Total Number of Nuclear Pore Complexes per Cell Nucleus.” <i>Genes &#38; Development</i>.
    Cold Spring Harbor Laboratory, 2018. <a href="https://doi.org/10.1101/gad.315523.118">https://doi.org/10.1101/gad.315523.118</a>.
  ieee: A. McCloskey, A. Ibarra, and M. Hetzer, “Tpr regulates the total number of
    nuclear pore complexes per cell nucleus,” <i>Genes &#38; Development</i>, vol.
    32, no. 19–20. Cold Spring Harbor Laboratory, pp. 1321–1331, 2018.
  ista: McCloskey A, Ibarra A, Hetzer M. 2018. Tpr regulates the total number of nuclear
    pore complexes per cell nucleus. Genes &#38; Development. 32(19–20), 1321–1331.
  mla: McCloskey, Asako, et al. “Tpr Regulates the Total Number of Nuclear Pore Complexes
    per Cell Nucleus.” <i>Genes &#38; Development</i>, vol. 32, no. 19–20, Cold Spring
    Harbor Laboratory, 2018, pp. 1321–31, doi:<a href="https://doi.org/10.1101/gad.315523.118">10.1101/gad.315523.118</a>.
  short: A. McCloskey, A. Ibarra, M. Hetzer, Genes &#38; Development 32 (2018) 1321–1331.
date_created: 2022-04-07T07:45:30Z
date_published: 2018-09-18T00:00:00Z
date_updated: 2022-07-18T08:32:32Z
day: '18'
doi: 10.1101/gad.315523.118
extern: '1'
external_id:
  pmid:
  - '30228202'
intvolume: '        32'
issue: 19-20
keyword:
- Developmental Biology
- Genetics
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1101/gad.315523.118
month: '09'
oa: 1
oa_version: Published Version
page: 1321-1331
pmid: 1
publication: Genes & Development
publication_identifier:
  issn:
  - 0890-9369
  - 1549-5477
publication_status: published
publisher: Cold Spring Harbor Laboratory
quality_controlled: '1'
scopus_import: '1'
status: public
title: Tpr regulates the total number of nuclear pore complexes per cell nucleus
type: journal_article
user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd
volume: 32
year: '2018'
...
---
_id: '11064'
abstract:
- lang: eng
  text: Biomarkers of aging can be used to assess the health of individuals and to
    study aging and age-related diseases. We generate a large dataset of genome-wide
    RNA-seq profiles of human dermal fibroblasts from 133 people aged 1 to 94 years
    old to test whether signatures of aging are encoded within the transcriptome.
    We develop an ensemble machine learning method that predicts age to a median error
    of 4 years, outperforming previous methods used to predict age. The ensemble was
    further validated by testing it on ten progeria patients, and our method is the
    only one that predicts accelerated aging in these patients.
article_number: '221'
article_processing_charge: No
article_type: original
author:
- first_name: Jason G.
  full_name: Fleischer, Jason G.
  last_name: Fleischer
- first_name: Roberta
  full_name: Schulte, Roberta
  last_name: Schulte
- first_name: Hsiao H.
  full_name: Tsai, Hsiao H.
  last_name: Tsai
- first_name: Swati
  full_name: Tyagi, Swati
  last_name: Tyagi
- first_name: Arkaitz
  full_name: Ibarra, Arkaitz
  last_name: Ibarra
- first_name: Maxim N.
  full_name: Shokhirev, Maxim N.
  last_name: Shokhirev
- first_name: Ling
  full_name: Huang, Ling
  last_name: Huang
- first_name: Martin W
  full_name: HETZER, Martin W
  id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
  last_name: HETZER
  orcid: 0000-0002-2111-992X
- first_name: Saket
  full_name: Navlakha, Saket
  last_name: Navlakha
citation:
  ama: Fleischer JG, Schulte R, Tsai HH, et al. Predicting age from the transcriptome
    of human dermal fibroblasts. <i>Genome Biology</i>. 2018;19. doi:<a href="https://doi.org/10.1186/s13059-018-1599-6">10.1186/s13059-018-1599-6</a>
  apa: Fleischer, J. G., Schulte, R., Tsai, H. H., Tyagi, S., Ibarra, A., Shokhirev,
    M. N., … Navlakha, S. (2018). Predicting age from the transcriptome of human dermal
    fibroblasts. <i>Genome Biology</i>. BioMed Central. <a href="https://doi.org/10.1186/s13059-018-1599-6">https://doi.org/10.1186/s13059-018-1599-6</a>
  chicago: Fleischer, Jason G., Roberta Schulte, Hsiao H. Tsai, Swati Tyagi, Arkaitz
    Ibarra, Maxim N. Shokhirev, Ling Huang, Martin Hetzer, and Saket Navlakha. “Predicting
    Age from the Transcriptome of Human Dermal Fibroblasts.” <i>Genome Biology</i>.
    BioMed Central, 2018. <a href="https://doi.org/10.1186/s13059-018-1599-6">https://doi.org/10.1186/s13059-018-1599-6</a>.
  ieee: J. G. Fleischer <i>et al.</i>, “Predicting age from the transcriptome of human
    dermal fibroblasts,” <i>Genome Biology</i>, vol. 19. BioMed Central, 2018.
  ista: Fleischer JG, Schulte R, Tsai HH, Tyagi S, Ibarra A, Shokhirev MN, Huang L,
    Hetzer M, Navlakha S. 2018. Predicting age from the transcriptome of human dermal
    fibroblasts. Genome Biology. 19, 221.
  mla: Fleischer, Jason G., et al. “Predicting Age from the Transcriptome of Human
    Dermal Fibroblasts.” <i>Genome Biology</i>, vol. 19, 221, BioMed Central, 2018,
    doi:<a href="https://doi.org/10.1186/s13059-018-1599-6">10.1186/s13059-018-1599-6</a>.
  short: J.G. Fleischer, R. Schulte, H.H. Tsai, S. Tyagi, A. Ibarra, M.N. Shokhirev,
    L. Huang, M. Hetzer, S. Navlakha, Genome Biology 19 (2018).
date_created: 2022-04-07T07:45:40Z
date_published: 2018-12-20T00:00:00Z
date_updated: 2022-07-18T08:32:34Z
day: '20'
doi: 10.1186/s13059-018-1599-6
extern: '1'
external_id:
  pmid:
  - '30567591'
intvolume: '        19'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1186/s13059-018-1599-6
month: '12'
oa: 1
oa_version: Published Version
pmid: 1
publication: Genome Biology
publication_identifier:
  issn:
  - 1474-760X
publication_status: published
publisher: BioMed Central
quality_controlled: '1'
scopus_import: '1'
status: public
title: Predicting age from the transcriptome of human dermal fibroblasts
type: journal_article
user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd
volume: 19
year: '2018'
...
