---
_id: '198'
abstract:
- lang: eng
  text: We consider a class of students learning a language from a teacher. The situation
    can be interpreted as a group of child learners receiving input from the linguistic
    environment. The teacher provides sample sentences. The students try to learn
    the grammar from the teacher. In addition to just listening to the teacher, the
    students can also communicate with each other. The students hold hypotheses about
    the grammar and change them if they receive counter evidence. The process stops
    when all students have converged to the correct grammar. We study how the time
    to convergence depends on the structure of the classroom by introducing and evaluating
    various complexity measures. We find that structured communication between students,
    although potentially introducing confusion, can greatly reduce some of the complexity
    measures. Our theory can also be interpreted as applying to the scientific process,
    where nature is the teacher and the scientists are the students.
article_number: '20180073'
article_processing_charge: No
article_type: original
author:
- first_name: Rasmus
  full_name: Ibsen-Jensen, Rasmus
  id: 3B699956-F248-11E8-B48F-1D18A9856A87
  last_name: Ibsen-Jensen
  orcid: 0000-0003-4783-0389
- first_name: Josef
  full_name: Tkadlec, Josef
  id: 3F24CCC8-F248-11E8-B48F-1D18A9856A87
  last_name: Tkadlec
  orcid: 0000-0002-1097-9684
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Martin
  full_name: Nowak, Martin
  last_name: Nowak
citation:
  ama: Ibsen-Jensen R, Tkadlec J, Chatterjee K, Nowak M. Language acquisition with
    communication between learners. <i>Journal of the Royal Society Interface</i>.
    2018;15(140). doi:<a href="https://doi.org/10.1098/rsif.2018.0073">10.1098/rsif.2018.0073</a>
  apa: Ibsen-Jensen, R., Tkadlec, J., Chatterjee, K., &#38; Nowak, M. (2018). Language
    acquisition with communication between learners. <i>Journal of the Royal Society
    Interface</i>. The Royal Society. <a href="https://doi.org/10.1098/rsif.2018.0073">https://doi.org/10.1098/rsif.2018.0073</a>
  chicago: Ibsen-Jensen, Rasmus, Josef Tkadlec, Krishnendu Chatterjee, and Martin
    Nowak. “Language Acquisition with Communication between Learners.” <i>Journal
    of the Royal Society Interface</i>. The Royal Society, 2018. <a href="https://doi.org/10.1098/rsif.2018.0073">https://doi.org/10.1098/rsif.2018.0073</a>.
  ieee: R. Ibsen-Jensen, J. Tkadlec, K. Chatterjee, and M. Nowak, “Language acquisition
    with communication between learners,” <i>Journal of the Royal Society Interface</i>,
    vol. 15, no. 140. The Royal Society, 2018.
  ista: Ibsen-Jensen R, Tkadlec J, Chatterjee K, Nowak M. 2018. Language acquisition
    with communication between learners. Journal of the Royal Society Interface. 15(140),
    20180073.
  mla: Ibsen-Jensen, Rasmus, et al. “Language Acquisition with Communication between
    Learners.” <i>Journal of the Royal Society Interface</i>, vol. 15, no. 140, 20180073,
    The Royal Society, 2018, doi:<a href="https://doi.org/10.1098/rsif.2018.0073">10.1098/rsif.2018.0073</a>.
  short: R. Ibsen-Jensen, J. Tkadlec, K. Chatterjee, M. Nowak, Journal of the Royal
    Society Interface 15 (2018).
date_created: 2018-12-11T11:45:09Z
date_published: 2018-03-01T00:00:00Z
date_updated: 2023-10-18T06:36:00Z
day: '01'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.1098/rsif.2018.0073
ec_funded: 1
external_id:
  isi:
  - '000428576200023'
  pmid:
  - '29593089'
file:
- access_level: open_access
  checksum: 444e1a9d98eb0e780671be82b13025f3
  content_type: application/pdf
  creator: dernst
  date_created: 2019-02-12T07:54:37Z
  date_updated: 2020-07-14T12:45:22Z
  file_id: '5955'
  file_name: 2018_RS_IbsenJensen.pdf
  file_size: 219837
  relation: main_file
file_date_updated: 2020-07-14T12:45:22Z
has_accepted_license: '1'
intvolume: '        15'
isi: 1
issue: '140'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Submitted Version
pmid: 1
project:
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '279307'
  name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2584A770-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P 23499-N23
  name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S 11407_N23
  name: Rigorous Systems Engineering
publication: Journal of the Royal Society Interface
publication_identifier:
  eissn:
  - 1742-5662
publication_status: published
publisher: The Royal Society
publist_id: '7715'
quality_controlled: '1'
related_material:
  link:
  - relation: supplementary_material
    url: https://dx.doi.org/10.6084/m9.figshare.c.4028971
  record:
  - id: '9814'
    relation: research_data
    status: public
scopus_import: '1'
status: public
title: Language acquisition with communication between learners
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 15
year: '2018'
...
---
_id: '199'
abstract:
- lang: eng
  text: Sex-biased genes are central to the study of sexual selection, sexual antagonism,
    and sex chromosome evolution. We describe a comprehensive de novo assembled transcriptome
    in the common frog Rana temporaria based on five developmental stages and three
    adult tissues from both sexes, obtained from a population with karyotypically
    homomorphic but genetically differentiated sex chromosomes. This allows the study
    of sex-biased gene expression throughout development, and its effect on the rate
    of gene evolution while accounting for pleiotropic expression, which is known
    to negatively correlate with the evolutionary rate. Overall, sex-biased genes
    had little overlap among developmental stages and adult tissues. Late developmental
    stages and gonad tissues had the highest numbers of stage-or tissue-specific genes.
    We find that pleiotropic gene expression is a better predictor than sex bias for
    the evolutionary rate of genes, though it often interacts with sex bias. Although
    genetically differentiated, the sex chromosomes were not enriched in sex-biased
    genes, possibly due to a very recent arrest of XY recombination. These results
    extend our understanding of the developmental dynamics, tissue specificity, and
    genomic localization of sex-biased genes.
article_number: '294'
article_processing_charge: No
author:
- first_name: Wen
  full_name: Ma, Wen
  last_name: Ma
- first_name: Paris
  full_name: Veltsos, Paris
  last_name: Veltsos
- first_name: Melissa A
  full_name: Toups, Melissa A
  id: 4E099E4E-F248-11E8-B48F-1D18A9856A87
  last_name: Toups
  orcid: 0000-0002-9752-7380
- first_name: Nicolas
  full_name: Rodrigues, Nicolas
  last_name: Rodrigues
- first_name: Roberto
  full_name: Sermier, Roberto
  last_name: Sermier
- first_name: Daniel
  full_name: Jeffries, Daniel
  last_name: Jeffries
- first_name: Nicolas
  full_name: Perrin, Nicolas
  last_name: Perrin
citation:
  ama: Ma W, Veltsos P, Toups MA, et al. Tissue specificity and dynamics of sex biased
    gene expression in a common frog population with differentiated, yet homomorphic,
    sex chromosomes. <i>Genes</i>. 2018;9(6). doi:<a href="https://doi.org/10.3390/genes9060294">10.3390/genes9060294</a>
  apa: Ma, W., Veltsos, P., Toups, M. A., Rodrigues, N., Sermier, R., Jeffries, D.,
    &#38; Perrin, N. (2018). Tissue specificity and dynamics of sex biased gene expression
    in a common frog population with differentiated, yet homomorphic, sex chromosomes.
    <i>Genes</i>. MDPI AG. <a href="https://doi.org/10.3390/genes9060294">https://doi.org/10.3390/genes9060294</a>
  chicago: Ma, Wen, Paris Veltsos, Melissa A Toups, Nicolas Rodrigues, Roberto Sermier,
    Daniel Jeffries, and Nicolas Perrin. “Tissue Specificity and Dynamics of Sex Biased
    Gene Expression in a Common Frog Population with Differentiated, yet Homomorphic,
    Sex Chromosomes.” <i>Genes</i>. MDPI AG, 2018. <a href="https://doi.org/10.3390/genes9060294">https://doi.org/10.3390/genes9060294</a>.
  ieee: W. Ma <i>et al.</i>, “Tissue specificity and dynamics of sex biased gene expression
    in a common frog population with differentiated, yet homomorphic, sex chromosomes,”
    <i>Genes</i>, vol. 9, no. 6. MDPI AG, 2018.
  ista: Ma W, Veltsos P, Toups MA, Rodrigues N, Sermier R, Jeffries D, Perrin N. 2018.
    Tissue specificity and dynamics of sex biased gene expression in a common frog
    population with differentiated, yet homomorphic, sex chromosomes. Genes. 9(6),
    294.
  mla: Ma, Wen, et al. “Tissue Specificity and Dynamics of Sex Biased Gene Expression
    in a Common Frog Population with Differentiated, yet Homomorphic, Sex Chromosomes.”
    <i>Genes</i>, vol. 9, no. 6, 294, MDPI AG, 2018, doi:<a href="https://doi.org/10.3390/genes9060294">10.3390/genes9060294</a>.
  short: W. Ma, P. Veltsos, M.A. Toups, N. Rodrigues, R. Sermier, D. Jeffries, N.
    Perrin, Genes 9 (2018).
date_created: 2018-12-11T11:45:09Z
date_published: 2018-06-12T00:00:00Z
date_updated: 2023-09-19T10:15:31Z
day: '12'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.3390/genes9060294
external_id:
  isi:
  - '000436494200026'
file:
- access_level: open_access
  checksum: 423069beb1cd3cdd25bf3f464b38f1d7
  content_type: application/pdf
  creator: dernst
  date_created: 2019-02-01T07:52:28Z
  date_updated: 2020-07-14T12:45:22Z
  file_id: '5905'
  file_name: 2018_Genes_Ma.pdf
  file_size: 3985796
  relation: main_file
file_date_updated: 2020-07-14T12:45:22Z
has_accepted_license: '1'
intvolume: '         9'
isi: 1
issue: '6'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
publication: Genes
publication_status: published
publisher: MDPI AG
publist_id: '7714'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Tissue specificity and dynamics of sex biased gene expression in a common frog
  population with differentiated, yet homomorphic, sex chromosomes
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 9
year: '2018'
...
---
_id: '2'
abstract:
- lang: eng
  text: Indirect reciprocity explores how humans act when their reputation is at stake,
    and which social norms they use to assess the actions of others. A crucial question
    in indirect reciprocity is which social norms can maintain stable cooperation
    in a society. Past research has highlighted eight such norms, called “leading-eight”
    strategies. This past research, however, is based on the assumption that all relevant
    information about other population members is publicly available and that everyone
    agrees on who is good or bad. Instead, here we explore the reputation dynamics
    when information is private and noisy. We show that under these conditions, most
    leading-eight strategies fail to evolve. Those leading-eight strategies that do
    evolve are unable to sustain full cooperation.Indirect reciprocity is a mechanism
    for cooperation based on shared moral systems and individual reputations. It assumes
    that members of a community routinely observe and assess each other and that they
    use this information to decide who is good or bad, and who deserves cooperation.
    When information is transmitted publicly, such that all community members agree
    on each other’s reputation, previous research has highlighted eight crucial moral
    systems. These “leading-eight” strategies can maintain cooperation and resist
    invasion by defectors. However, in real populations individuals often hold their
    own private views of others. Once two individuals disagree about their opinion
    of some third party, they may also see its subsequent actions in a different light.
    Their opinions may further diverge over time. Herein, we explore indirect reciprocity
    when information transmission is private and noisy. We find that in the presence
    of perception errors, most leading-eight strategies cease to be stable. Even if
    a leading-eight strategy evolves, cooperation rates may drop considerably when
    errors are common. Our research highlights the role of reliable information and
    synchronized reputations to maintain stable moral systems.
article_processing_charge: No
author:
- first_name: Christian
  full_name: Hilbe, Christian
  id: 2FDF8F3C-F248-11E8-B48F-1D18A9856A87
  last_name: Hilbe
  orcid: 0000-0001-5116-955X
- first_name: Laura
  full_name: Schmid, Laura
  id: 38B437DE-F248-11E8-B48F-1D18A9856A87
  last_name: Schmid
  orcid: 0000-0002-6978-7329
- first_name: Josef
  full_name: Tkadlec, Josef
  id: 3F24CCC8-F248-11E8-B48F-1D18A9856A87
  last_name: Tkadlec
  orcid: 0000-0002-1097-9684
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Martin
  full_name: Nowak, Martin
  last_name: Nowak
citation:
  ama: Hilbe C, Schmid L, Tkadlec J, Chatterjee K, Nowak M. Indirect reciprocity with
    private, noisy, and incomplete information. <i>PNAS</i>. 2018;115(48):12241-12246.
    doi:<a href="https://doi.org/10.1073/pnas.1810565115">10.1073/pnas.1810565115</a>
  apa: Hilbe, C., Schmid, L., Tkadlec, J., Chatterjee, K., &#38; Nowak, M. (2018).
    Indirect reciprocity with private, noisy, and incomplete information. <i>PNAS</i>.
    National Academy of Sciences. <a href="https://doi.org/10.1073/pnas.1810565115">https://doi.org/10.1073/pnas.1810565115</a>
  chicago: Hilbe, Christian, Laura Schmid, Josef Tkadlec, Krishnendu Chatterjee, and
    Martin Nowak. “Indirect Reciprocity with Private, Noisy, and Incomplete Information.”
    <i>PNAS</i>. National Academy of Sciences, 2018. <a href="https://doi.org/10.1073/pnas.1810565115">https://doi.org/10.1073/pnas.1810565115</a>.
  ieee: C. Hilbe, L. Schmid, J. Tkadlec, K. Chatterjee, and M. Nowak, “Indirect reciprocity
    with private, noisy, and incomplete information,” <i>PNAS</i>, vol. 115, no. 48.
    National Academy of Sciences, pp. 12241–12246, 2018.
  ista: Hilbe C, Schmid L, Tkadlec J, Chatterjee K, Nowak M. 2018. Indirect reciprocity
    with private, noisy, and incomplete information. PNAS. 115(48), 12241–12246.
  mla: Hilbe, Christian, et al. “Indirect Reciprocity with Private, Noisy, and Incomplete
    Information.” <i>PNAS</i>, vol. 115, no. 48, National Academy of Sciences, 2018,
    pp. 12241–46, doi:<a href="https://doi.org/10.1073/pnas.1810565115">10.1073/pnas.1810565115</a>.
  short: C. Hilbe, L. Schmid, J. Tkadlec, K. Chatterjee, M. Nowak, PNAS 115 (2018)
    12241–12246.
date_created: 2018-12-11T11:44:05Z
date_published: 2018-11-27T00:00:00Z
date_updated: 2025-07-14T09:10:09Z
day: '27'
department:
- _id: KrCh
doi: 10.1073/pnas.1810565115
ec_funded: 1
external_id:
  isi:
  - '000451351000063'
  pmid:
  - '30429320'
intvolume: '       115'
isi: 1
issue: '48'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pubmed/30429320
month: '11'
oa: 1
oa_version: Submitted Version
page: 12241-12246
pmid: 1
project:
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '279307'
  name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2584A770-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P 23499-N23
  name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S 11407_N23
  name: Rigorous Systems Engineering
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
quality_controlled: '1'
related_material:
  link:
  - description: News on IST Homepage
    relation: press_release
    url: https://ist.ac.at/en/news/no-cooperation-without-open-communication/
  record:
  - id: '10293'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Indirect reciprocity with private, noisy, and incomplete information
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 115
year: '2018'
...
---
_id: '20'
abstract:
- lang: eng
  text: 'Background: Norepinephrine (NE) signaling has a key role in white adipose
    tissue (WAT) functions, including lipolysis, free fatty acid liberation and, under
    certain conditions, conversion of white into brite (brown-in-white) adipocytes.
    However, acute effects of NE stimulation have not been described at the transcriptional
    network level. Results: We used RNA-seq to uncover a broad transcriptional response.
    The inference of protein-protein and protein-DNA interaction networks allowed
    us to identify a set of immediate-early genes (IEGs) with high betweenness, validating
    our approach and suggesting a hierarchical control of transcriptional regulation.
    In addition, we identified a transcriptional regulatory network with IEGs as master
    regulators, including HSF1 and NFIL3 as novel NE-induced IEG candidates. Moreover,
    a functional enrichment analysis and gene clustering into functional modules suggest
    a crosstalk between metabolic, signaling, and immune responses. Conclusions: Altogether,
    our network biology approach explores for the first time the immediate-early systems
    level response of human adipocytes to acute sympathetic activation, thereby providing
    a first network basis of early cell fate programs and crosstalks between metabolic
    and transcriptional networks required for proper WAT function.'
acknowledgement: This work was funded by the German Centre for Diabetes Research (DZD)
  and the Austrian Science Fund (FWF, P25729-B19).
article_processing_charge: No
article_type: original
author:
- first_name: Juan
  full_name: Higareda Almaraz, Juan
  last_name: Higareda Almaraz
- first_name: Michael
  full_name: Karbiener, Michael
  last_name: Karbiener
- first_name: Maude
  full_name: Giroud, Maude
  last_name: Giroud
- first_name: Florian
  full_name: Pauler, Florian
  id: 48EA0138-F248-11E8-B48F-1D18A9856A87
  last_name: Pauler
  orcid: 0000-0002-7462-0048
- first_name: Teresa
  full_name: Gerhalter, Teresa
  last_name: Gerhalter
- first_name: Stephan
  full_name: Herzig, Stephan
  last_name: Herzig
- first_name: Marcel
  full_name: Scheideler, Marcel
  last_name: Scheideler
citation:
  ama: Higareda Almaraz J, Karbiener M, Giroud M, et al. Norepinephrine triggers an
    immediate-early regulatory network response in primary human white adipocytes.
    <i>BMC Genomics</i>. 2018;19(1). doi:<a href="https://doi.org/10.1186/s12864-018-5173-0">10.1186/s12864-018-5173-0</a>
  apa: Higareda Almaraz, J., Karbiener, M., Giroud, M., Pauler, F., Gerhalter, T.,
    Herzig, S., &#38; Scheideler, M. (2018). Norepinephrine triggers an immediate-early
    regulatory network response in primary human white adipocytes. <i>BMC Genomics</i>.
    BioMed Central. <a href="https://doi.org/10.1186/s12864-018-5173-0">https://doi.org/10.1186/s12864-018-5173-0</a>
  chicago: Higareda Almaraz, Juan, Michael Karbiener, Maude Giroud, Florian Pauler,
    Teresa Gerhalter, Stephan Herzig, and Marcel Scheideler. “Norepinephrine Triggers
    an Immediate-Early Regulatory Network Response in Primary Human White Adipocytes.”
    <i>BMC Genomics</i>. BioMed Central, 2018. <a href="https://doi.org/10.1186/s12864-018-5173-0">https://doi.org/10.1186/s12864-018-5173-0</a>.
  ieee: J. Higareda Almaraz <i>et al.</i>, “Norepinephrine triggers an immediate-early
    regulatory network response in primary human white adipocytes,” <i>BMC Genomics</i>,
    vol. 19, no. 1. BioMed Central, 2018.
  ista: Higareda Almaraz J, Karbiener M, Giroud M, Pauler F, Gerhalter T, Herzig S,
    Scheideler M. 2018. Norepinephrine triggers an immediate-early regulatory network
    response in primary human white adipocytes. BMC Genomics. 19(1).
  mla: Higareda Almaraz, Juan, et al. “Norepinephrine Triggers an Immediate-Early
    Regulatory Network Response in Primary Human White Adipocytes.” <i>BMC Genomics</i>,
    vol. 19, no. 1, BioMed Central, 2018, doi:<a href="https://doi.org/10.1186/s12864-018-5173-0">10.1186/s12864-018-5173-0</a>.
  short: J. Higareda Almaraz, M. Karbiener, M. Giroud, F. Pauler, T. Gerhalter, S.
    Herzig, M. Scheideler, BMC Genomics 19 (2018).
date_created: 2018-12-11T11:44:12Z
date_published: 2018-11-03T00:00:00Z
date_updated: 2023-09-13T09:10:47Z
day: '03'
ddc:
- '570'
department:
- _id: SiHi
doi: 10.1186/s12864-018-5173-0
external_id:
  isi:
  - '000450976700002'
file:
- access_level: open_access
  checksum: a56516e734dab589dc7f3e1915973b4d
  content_type: application/pdf
  creator: dernst
  date_created: 2018-12-17T14:52:57Z
  date_updated: 2020-07-14T12:45:23Z
  file_id: '5712'
  file_name: 2018_BMCGenomics_Higareda.pdf
  file_size: 4629784
  relation: main_file
file_date_updated: 2020-07-14T12:45:23Z
has_accepted_license: '1'
intvolume: '        19'
isi: 1
issue: '1'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
publication: BMC Genomics
publication_identifier:
  issn:
  - 1471-2164
publication_status: published
publisher: BioMed Central
publist_id: '8035'
quality_controlled: '1'
related_material:
  record:
  - id: '9807'
    relation: research_data
    status: public
  - id: '9808'
    relation: research_data
    status: public
scopus_import: '1'
status: public
title: Norepinephrine triggers an immediate-early regulatory network response in primary
  human white adipocytes
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 19
year: '2018'
...
---
_id: '200'
abstract:
- lang: eng
  text: This thesis is concerned with the inference of current population structure
    based on geo-referenced genetic data. The underlying idea is that population structure
    affects its spatial genetic structure. Therefore, genotype information can be
    utilized to estimate important demographic parameters such as migration rates.
    These indirect estimates of population structure have become very attractive,
    as genotype data is now widely available. However, there also has been much concern
    about these approaches. Importantly, genetic structure can be influenced by many
    complex patterns, which often cannot be disentangled. Moreover, many methods merely
    fit heuristic patterns of genetic structure, and do not build upon population
    genetics theory. Here, I describe two novel inference methods that address these
    shortcomings. In Chapter 2, I introduce an inference scheme based on a new type
    of signal, identity by descent (IBD) blocks. Recently, it has become feasible
    to detect such long blocks of genome shared between pairs of samples. These blocks
    are direct traces of recent coalescence events. As such, they contain ample signal
    for inferring recent demography. I examine sharing of IBD blocks in two-dimensional
    populations with local migration. Using a diffusion approximation, I derive formulas
    for an isolation by distance pattern of long IBD blocks and show that sharing
    of long IBD blocks approaches rapid exponential decay for growing sample distance.
    I describe an inference scheme based on these results. It can robustly estimate
    the dispersal rate and population density, which is demonstrated on simulated
    data. I also show an application to estimate mean migration and the rate of recent
    population growth within Eastern Europe. Chapter 3 is about a novel method to
    estimate barriers to gene flow in a two dimensional population. This inference
    scheme utilizes geographically localized allele frequency fluctuations - a classical
    isolation by distance signal. The strength of these local fluctuations increases
    on average next to a barrier, and there is less correlation across it. I again
    use a framework of diffusion of ancestral lineages to model this effect, and provide
    an efficient numerical implementation to fit the results to geo-referenced biallelic
    SNP data. This inference scheme is able to robustly estimate strong barriers to
    gene flow, as tests on simulated data confirm.
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Harald
  full_name: Ringbauer, Harald
  id: 417FCFF4-F248-11E8-B48F-1D18A9856A87
  last_name: Ringbauer
  orcid: 0000-0002-4884-9682
citation:
  ama: Ringbauer H. Inferring recent demography from spatial genetic structure. 2018.
    doi:<a href="https://doi.org/10.15479/AT:ISTA:th_963">10.15479/AT:ISTA:th_963</a>
  apa: Ringbauer, H. (2018). <i>Inferring recent demography from spatial genetic structure</i>.
    Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:th_963">https://doi.org/10.15479/AT:ISTA:th_963</a>
  chicago: Ringbauer, Harald. “Inferring Recent Demography from Spatial Genetic Structure.”
    Institute of Science and Technology Austria, 2018. <a href="https://doi.org/10.15479/AT:ISTA:th_963">https://doi.org/10.15479/AT:ISTA:th_963</a>.
  ieee: H. Ringbauer, “Inferring recent demography from spatial genetic structure,”
    Institute of Science and Technology Austria, 2018.
  ista: Ringbauer H. 2018. Inferring recent demography from spatial genetic structure.
    Institute of Science and Technology Austria.
  mla: Ringbauer, Harald. <i>Inferring Recent Demography from Spatial Genetic Structure</i>.
    Institute of Science and Technology Austria, 2018, doi:<a href="https://doi.org/10.15479/AT:ISTA:th_963">10.15479/AT:ISTA:th_963</a>.
  short: H. Ringbauer, Inferring Recent Demography from Spatial Genetic Structure,
    Institute of Science and Technology Austria, 2018.
date_created: 2018-12-11T11:45:10Z
date_published: 2018-02-21T00:00:00Z
date_updated: 2025-05-28T11:57:06Z
day: '21'
ddc:
- '576'
degree_awarded: PhD
department:
- _id: NiBa
doi: 10.15479/AT:ISTA:th_963
file:
- access_level: open_access
  checksum: 8cc534d2b528ae017acf80874cce48c9
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:14:55Z
  date_updated: 2020-07-14T12:45:23Z
  file_id: '5111'
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  checksum: 6af18d7e5a7e2728ceda2f41ee24f628
  content_type: application/zip
  creator: dernst
  date_created: 2019-04-05T09:30:12Z
  date_updated: 2020-07-14T12:45:23Z
  file_id: '6224'
  file_name: 2018_thesis_ringbauer_source.zip
  file_size: 113365
  relation: source_file
file_date_updated: 2020-07-14T12:45:23Z
has_accepted_license: '1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc/4.0/
month: '02'
oa: 1
oa_version: Published Version
page: '146'
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
publist_id: '7713'
pubrep_id: '963'
related_material:
  record:
  - id: '563'
    relation: part_of_dissertation
    status: public
  - id: '1074'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
title: Inferring recent demography from spatial genetic structure
tmp:
  image: /images/cc_by_nc.png
  legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
  short: CC BY-NC (4.0)
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2018'
...
---
_id: '201'
abstract:
- lang: eng
  text: 'We describe arrangements of three-dimensional spheres from a geometrical
    and topological point of view. Real data (fitting this setup) often consist of
    soft spheres which show certain degree of deformation while strongly packing against
    each other. In this context, we answer the following questions: If we model a
    soft packing of spheres by hard spheres that are allowed to overlap, can we measure
    the volume in the overlapped areas? Can we be more specific about the overlap
    volume, i.e. quantify how much volume is there covered exactly twice, three times,
    or k times? What would be a good optimization criteria that rule the arrangement
    of soft spheres while making a good use of the available space? Fixing a particular
    criterion, what would be the optimal sphere configuration? The first result of
    this thesis are short formulas for the computation of volumes covered by at least
    k of the balls. The formulas exploit information contained in the order-k Voronoi
    diagrams and its closely related Level-k complex. The used complexes lead to a
    natural generalization into poset diagrams, a theoretical formalism that contains
    the order-k and degree-k diagrams as special cases. In parallel, we define different
    criteria to determine what could be considered an optimal arrangement from a geometrical
    point of view. Fixing a criterion, we find optimal soft packing configurations
    in 2D and 3D where the ball centers lie on a lattice. As a last step, we use tools
    from computational topology on real physical data, to show the potentials of higher-order
    diagrams in the description of melting crystals. The results of the experiments
    leaves us with an open window to apply the theories developed in this thesis in
    real applications.'
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Mabel
  full_name: Iglesias Ham, Mabel
  id: 41B58C0C-F248-11E8-B48F-1D18A9856A87
  last_name: Iglesias Ham
citation:
  ama: Iglesias Ham M. Multiple covers with balls. 2018. doi:<a href="https://doi.org/10.15479/AT:ISTA:th_1026">10.15479/AT:ISTA:th_1026</a>
  apa: Iglesias Ham, M. (2018). <i>Multiple covers with balls</i>. Institute of Science
    and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:th_1026">https://doi.org/10.15479/AT:ISTA:th_1026</a>
  chicago: Iglesias Ham, Mabel. “Multiple Covers with Balls.” Institute of Science
    and Technology Austria, 2018. <a href="https://doi.org/10.15479/AT:ISTA:th_1026">https://doi.org/10.15479/AT:ISTA:th_1026</a>.
  ieee: M. Iglesias Ham, “Multiple covers with balls,” Institute of Science and Technology
    Austria, 2018.
  ista: Iglesias Ham M. 2018. Multiple covers with balls. Institute of Science and
    Technology Austria.
  mla: Iglesias Ham, Mabel. <i>Multiple Covers with Balls</i>. Institute of Science
    and Technology Austria, 2018, doi:<a href="https://doi.org/10.15479/AT:ISTA:th_1026">10.15479/AT:ISTA:th_1026</a>.
  short: M. Iglesias Ham, Multiple Covers with Balls, Institute of Science and Technology
    Austria, 2018.
date_created: 2018-12-11T11:45:10Z
date_published: 2018-06-11T00:00:00Z
date_updated: 2023-09-07T12:25:32Z
day: '11'
ddc:
- '514'
- '516'
degree_awarded: PhD
department:
- _id: HeEd
doi: 10.15479/AT:ISTA:th_1026
file:
- access_level: closed
  checksum: dd699303623e96d1478a6ae07210dd05
  content_type: application/zip
  creator: kschuh
  date_created: 2019-02-05T07:43:31Z
  date_updated: 2020-07-14T12:45:24Z
  file_id: '5918'
  file_name: IST-2018-1025-v2+5_ist-thesis-iglesias-11June2018(1).zip
  file_size: 11827713
  relation: source_file
- access_level: open_access
  checksum: ba163849a190d2b41d66fef0e4983294
  content_type: application/pdf
  creator: kschuh
  date_created: 2019-02-05T07:43:45Z
  date_updated: 2020-07-14T12:45:24Z
  file_id: '5919'
  file_name: IST-2018-1025-v2+4_ThesisIglesiasFinal11June2018.pdf
  file_size: 4783846
  relation: main_file
file_date_updated: 2020-07-14T12:45:24Z
has_accepted_license: '1'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: '171'
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
publist_id: '7712'
pubrep_id: '1026'
status: public
supervisor:
- first_name: Herbert
  full_name: Edelsbrunner, Herbert
  id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
  last_name: Edelsbrunner
  orcid: 0000-0002-9823-6833
title: Multiple covers with balls
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2018'
...
---
_id: '2015'
abstract:
- lang: eng
  text: We consider the problem of learning a Bayesian network or directed acyclic
    graph model from observational data. A number of constraint‐based, score‐based
    and hybrid algorithms have been developed for this purpose. Statistical consistency
    guarantees of these algorithms rely on the faithfulness assumption, which has
    been shown to be restrictive especially for graphs with cycles in the skeleton.
    We here propose the sparsest permutation (SP) algorithm, showing that learning
    Bayesian networks is possible under strictly weaker assumptions than faithfulness.
    This comes at a computational price, thereby indicating a statistical‐computational
    trade‐off for causal inference algorithms. In the Gaussian noiseless setting,
    we prove that the SP algorithm boils down to finding the permutation of the variables
    with the sparsest Cholesky decomposition of the inverse covariance matrix, which
    is equivalent to ℓ0‐penalized maximum likelihood estimation. We end with a simulation
    study showing that in line with the proven stronger consistency guarantees, and
    the SP algorithm compares favourably to standard causal inference algorithms in
    terms of accuracy for a given sample size.
article_number: e183
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Garvesh
  full_name: Raskutti, Garvesh
  last_name: Raskutti
- first_name: Caroline
  full_name: Uhler, Caroline
  id: 49ADD78E-F248-11E8-B48F-1D18A9856A87
  last_name: Uhler
  orcid: 0000-0002-7008-0216
citation:
  ama: Raskutti G, Uhler C. Learning directed acyclic graphs based on sparsest permutations.
    <i>STAT</i>. 2018;7(1). doi:<a href="https://doi.org/10.1002/sta4.183">10.1002/sta4.183</a>
  apa: Raskutti, G., &#38; Uhler, C. (2018). Learning directed acyclic graphs based
    on sparsest permutations. <i>STAT</i>. Wiley. <a href="https://doi.org/10.1002/sta4.183">https://doi.org/10.1002/sta4.183</a>
  chicago: Raskutti, Garvesh, and Caroline Uhler. “Learning Directed Acyclic Graphs
    Based on Sparsest Permutations.” <i>STAT</i>. Wiley, 2018. <a href="https://doi.org/10.1002/sta4.183">https://doi.org/10.1002/sta4.183</a>.
  ieee: G. Raskutti and C. Uhler, “Learning directed acyclic graphs based on sparsest
    permutations,” <i>STAT</i>, vol. 7, no. 1. Wiley, 2018.
  ista: Raskutti G, Uhler C. 2018. Learning directed acyclic graphs based on sparsest
    permutations. STAT. 7(1), e183.
  mla: Raskutti, Garvesh, and Caroline Uhler. “Learning Directed Acyclic Graphs Based
    on Sparsest Permutations.” <i>STAT</i>, vol. 7, no. 1, e183, Wiley, 2018, doi:<a
    href="https://doi.org/10.1002/sta4.183">10.1002/sta4.183</a>.
  short: G. Raskutti, C. Uhler, STAT 7 (2018).
date_created: 2018-12-11T11:55:13Z
date_published: 2018-04-17T00:00:00Z
date_updated: 2021-01-12T06:54:44Z
day: '17'
doi: 10.1002/sta4.183
extern: '1'
external_id:
  arxiv:
  - '1307.0366'
intvolume: '         7'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://arxiv.org/abs/1307.0366
month: '04'
oa: 1
oa_version: Preprint
publication: STAT
publication_status: published
publisher: Wiley
publist_id: '5061'
quality_controlled: '1'
status: public
title: Learning directed acyclic graphs based on sparsest permutations
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2018'
...
---
_id: '203'
abstract:
- lang: eng
  text: Asymmetric auxin distribution is instrumental for the differential growth
    that causes organ bending on tropic stimuli and curvatures during plant development.
    Local differences in auxin concentrations are achieved mainly by polarized cellular
    distribution of PIN auxin transporters, but whether other mechanisms involving
    auxin homeostasis are also relevant for the formation of auxin gradients is not
    clear. Here we show that auxin methylation is required for asymmetric auxin distribution
    across the hypocotyl, particularly during its response to gravity. We found that
    loss-of-function mutants in Arabidopsis IAA CARBOXYL METHYLTRANSFERASE1 (IAMT1)
    prematurely unfold the apical hook, and that their hypocotyls are impaired in
    gravitropic reorientation. This defect is linked to an auxin-dependent increase
    in PIN gene expression, leading to an increased polar auxin transport and lack
    of asymmetric distribution of PIN3 in the iamt1 mutant. Gravitropic reorientation
    in the iamt1 mutant could be restored with either endodermis-specific expression
    of IAMT1 or partial inhibition of polar auxin transport, which also results in
    normal PIN gene expression levels. We propose that IAA methylation is necessary
    in gravity-sensing cells to restrict polar auxin transport within the range of
    auxin levels that allow for differential responses.
article_processing_charge: No
author:
- first_name: Mohamad
  full_name: Abbas, Mohamad
  id: 47E8FC1C-F248-11E8-B48F-1D18A9856A87
  last_name: Abbas
- first_name: García J
  full_name: Hernández, García J
  last_name: Hernández
- first_name: Stephan
  full_name: Pollmann, Stephan
  last_name: Pollmann
- first_name: Sophia L
  full_name: Samodelov, Sophia L
  last_name: Samodelov
- first_name: Martina
  full_name: Kolb, Martina
  last_name: Kolb
- first_name: Jirí
  full_name: Friml, Jirí
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Ulrich Z
  full_name: Hammes, Ulrich Z
  last_name: Hammes
- first_name: Matias D
  full_name: Zurbriggen, Matias D
  last_name: Zurbriggen
- first_name: Miguel
  full_name: Blázquez, Miguel
  last_name: Blázquez
- first_name: David
  full_name: Alabadí, David
  last_name: Alabadí
citation:
  ama: Abbas M, Hernández GJ, Pollmann S, et al. Auxin methylation is required for
    differential growth in Arabidopsis. <i>PNAS</i>. 2018;115(26):6864-6869. doi:<a
    href="https://doi.org/10.1073/pnas.1806565115">10.1073/pnas.1806565115</a>
  apa: Abbas, M., Hernández, G. J., Pollmann, S., Samodelov, S. L., Kolb, M., Friml,
    J., … Alabadí, D. (2018). Auxin methylation is required for differential growth
    in Arabidopsis. <i>PNAS</i>. National Academy of Sciences. <a href="https://doi.org/10.1073/pnas.1806565115">https://doi.org/10.1073/pnas.1806565115</a>
  chicago: Abbas, Mohamad, García J Hernández, Stephan Pollmann, Sophia L Samodelov,
    Martina Kolb, Jiří Friml, Ulrich Z Hammes, Matias D Zurbriggen, Miguel Blázquez,
    and David Alabadí. “Auxin Methylation Is Required for Differential Growth in Arabidopsis.”
    <i>PNAS</i>. National Academy of Sciences, 2018. <a href="https://doi.org/10.1073/pnas.1806565115">https://doi.org/10.1073/pnas.1806565115</a>.
  ieee: M. Abbas <i>et al.</i>, “Auxin methylation is required for differential growth
    in Arabidopsis,” <i>PNAS</i>, vol. 115, no. 26. National Academy of Sciences,
    pp. 6864–6869, 2018.
  ista: Abbas M, Hernández GJ, Pollmann S, Samodelov SL, Kolb M, Friml J, Hammes UZ,
    Zurbriggen MD, Blázquez M, Alabadí D. 2018. Auxin methylation is required for
    differential growth in Arabidopsis. PNAS. 115(26), 6864–6869.
  mla: Abbas, Mohamad, et al. “Auxin Methylation Is Required for Differential Growth
    in Arabidopsis.” <i>PNAS</i>, vol. 115, no. 26, National Academy of Sciences,
    2018, pp. 6864–69, doi:<a href="https://doi.org/10.1073/pnas.1806565115">10.1073/pnas.1806565115</a>.
  short: M. Abbas, G.J. Hernández, S. Pollmann, S.L. Samodelov, M. Kolb, J. Friml,
    U.Z. Hammes, M.D. Zurbriggen, M. Blázquez, D. Alabadí, PNAS 115 (2018) 6864–6869.
date_created: 2018-12-11T11:45:11Z
date_published: 2018-06-26T00:00:00Z
date_updated: 2025-05-07T11:12:32Z
day: '26'
department:
- _id: JiFr
doi: 10.1073/pnas.1806565115
ec_funded: 1
external_id:
  isi:
  - '000436245000096'
intvolume: '       115'
isi: 1
issue: '26'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://eprints.nottingham.ac.uk/52388/
month: '06'
oa: 1
oa_version: None
page: 6864-6869
project:
- _id: 25716A02-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '282300'
  name: Polarity and subcellular dynamics in plants
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '7710'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Auxin methylation is required for differential growth in Arabidopsis
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 115
year: '2018'
...
---
_id: '13374'
abstract:
- lang: eng
  text: Confining molecules to volumes only slightly larger than the molecules themselves
    can profoundly alter their properties. Molecular switches—entities that can be
    toggled between two or more forms upon exposure to an external stimulus—often
    require conformational freedom to isomerize. Therefore, placing these switches
    in confined spaces can render them non-operational. To preserve the switchability
    of these species under confinement, we work with a water-soluble coordination
    cage that is flexible enough to adapt its shape to the conformation of the encapsulated
    guest. We show that owing to its flexibility, the cage is not only capable of
    accommodating—and solubilizing in water—several light-responsive spiropyran-based
    molecular switches, but, more importantly, it also provides an environment suitable
    for the efficient, reversible photoisomerization of the bound guests. Our findings
    pave the way towards studying various molecular switching processes in confined
    environments.
article_number: '641'
article_processing_charge: No
article_type: original
author:
- first_name: Dipak
  full_name: Samanta, Dipak
  last_name: Samanta
- first_name: Daria
  full_name: Galaktionova, Daria
  last_name: Galaktionova
- first_name: Julius
  full_name: Gemen, Julius
  last_name: Gemen
- first_name: Linda J. W.
  full_name: Shimon, Linda J. W.
  last_name: Shimon
- first_name: Yael
  full_name: Diskin-Posner, Yael
  last_name: Diskin-Posner
- first_name: Liat
  full_name: Avram, Liat
  last_name: Avram
- first_name: Petr
  full_name: Král, Petr
  last_name: Král
- first_name: Rafal
  full_name: Klajn, Rafal
  id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
  last_name: Klajn
citation:
  ama: Samanta D, Galaktionova D, Gemen J, et al. Reversible chromism of spiropyran
    in the cavity of a flexible coordination cage. <i>Nature Communications</i>. 2018;9.
    doi:<a href="https://doi.org/10.1038/s41467-017-02715-6">10.1038/s41467-017-02715-6</a>
  apa: Samanta, D., Galaktionova, D., Gemen, J., Shimon, L. J. W., Diskin-Posner,
    Y., Avram, L., … Klajn, R. (2018). Reversible chromism of spiropyran in the cavity
    of a flexible coordination cage. <i>Nature Communications</i>. Springer Nature.
    <a href="https://doi.org/10.1038/s41467-017-02715-6">https://doi.org/10.1038/s41467-017-02715-6</a>
  chicago: Samanta, Dipak, Daria Galaktionova, Julius Gemen, Linda J. W. Shimon, Yael
    Diskin-Posner, Liat Avram, Petr Král, and Rafal Klajn. “Reversible Chromism of
    Spiropyran in the Cavity of a Flexible Coordination Cage.” <i>Nature Communications</i>.
    Springer Nature, 2018. <a href="https://doi.org/10.1038/s41467-017-02715-6">https://doi.org/10.1038/s41467-017-02715-6</a>.
  ieee: D. Samanta <i>et al.</i>, “Reversible chromism of spiropyran in the cavity
    of a flexible coordination cage,” <i>Nature Communications</i>, vol. 9. Springer
    Nature, 2018.
  ista: Samanta D, Galaktionova D, Gemen J, Shimon LJW, Diskin-Posner Y, Avram L,
    Král P, Klajn R. 2018. Reversible chromism of spiropyran in the cavity of a flexible
    coordination cage. Nature Communications. 9, 641.
  mla: Samanta, Dipak, et al. “Reversible Chromism of Spiropyran in the Cavity of
    a Flexible Coordination Cage.” <i>Nature Communications</i>, vol. 9, 641, Springer
    Nature, 2018, doi:<a href="https://doi.org/10.1038/s41467-017-02715-6">10.1038/s41467-017-02715-6</a>.
  short: D. Samanta, D. Galaktionova, J. Gemen, L.J.W. Shimon, Y. Diskin-Posner, L.
    Avram, P. Král, R. Klajn, Nature Communications 9 (2018).
date_created: 2023-08-01T09:39:32Z
date_published: 2018-02-13T00:00:00Z
date_updated: 2023-08-07T10:54:05Z
day: '13'
doi: 10.1038/s41467-017-02715-6
extern: '1'
external_id:
  pmid:
  - '29440687'
intvolume: '         9'
keyword:
- General Physics and Astronomy
- General Biochemistry
- Genetics and Molecular Biology
- General Chemistry
- Multidisciplinary
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1038/s41467-017-02715-6
month: '02'
oa: 1
oa_version: Published Version
pmid: 1
publication: Nature Communications
publication_identifier:
  eissn:
  - 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  link:
  - relation: erratum
    url: https://doi.org/10.1038/s41467-018-03701-2
scopus_import: '1'
status: public
title: Reversible chromism of spiropyran in the cavity of a flexible coordination
  cage
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9
year: '2018'
...
---
_id: '13375'
abstract:
- lang: eng
  text: 'Dissipative self-assembly leads to structures and materials that exist away
    from equilibrium by continuously exchanging energy and materials with the external
    environment. Although this mode of self-assembly is ubiquitous in nature, where
    it gives rise to functions such as signal processing, motility, self-healing,
    self-replication, and ultimately life, examples of dissipative self-assembly processes
    in man-made systems are few and far between. Herein, recent progress in developing
    diverse synthetic dissipative self-assembly systems is discussed. The systems
    reported thus far can be categorized into three classes, in which: i) the fuel
    chemically modifies the building blocks, thus triggering their self-assembly,
    ii) the fuel acts as a template interacting with the building blocks noncovalently,
    and iii) transient states are induced by the addition of two mutually exclusive
    stimuli. These early studies give rise to materials that would be difficult to
    obtain otherwise, including hydrogels with programmable lifetimes, vesicular nanoreactors,
    and membranes exhibiting transient conductivity.'
article_number: '1706750'
article_processing_charge: No
article_type: original
author:
- first_name: Soumen
  full_name: De, Soumen
  last_name: De
- first_name: Rafal
  full_name: Klajn, Rafal
  id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
  last_name: Klajn
citation:
  ama: De S, Klajn R. Dissipative self-assembly driven by the consumption of chemical
    fuels. <i>Advanced Materials</i>. 2018;30(41). doi:<a href="https://doi.org/10.1002/adma.201706750">10.1002/adma.201706750</a>
  apa: De, S., &#38; Klajn, R. (2018). Dissipative self-assembly driven by the consumption
    of chemical fuels. <i>Advanced Materials</i>. Wiley. <a href="https://doi.org/10.1002/adma.201706750">https://doi.org/10.1002/adma.201706750</a>
  chicago: De, Soumen, and Rafal Klajn. “Dissipative Self-Assembly Driven by the Consumption
    of Chemical Fuels.” <i>Advanced Materials</i>. Wiley, 2018. <a href="https://doi.org/10.1002/adma.201706750">https://doi.org/10.1002/adma.201706750</a>.
  ieee: S. De and R. Klajn, “Dissipative self-assembly driven by the consumption of
    chemical fuels,” <i>Advanced Materials</i>, vol. 30, no. 41. Wiley, 2018.
  ista: De S, Klajn R. 2018. Dissipative self-assembly driven by the consumption of
    chemical fuels. Advanced Materials. 30(41), 1706750.
  mla: De, Soumen, and Rafal Klajn. “Dissipative Self-Assembly Driven by the Consumption
    of Chemical Fuels.” <i>Advanced Materials</i>, vol. 30, no. 41, 1706750, Wiley,
    2018, doi:<a href="https://doi.org/10.1002/adma.201706750">10.1002/adma.201706750</a>.
  short: S. De, R. Klajn, Advanced Materials 30 (2018).
date_created: 2023-08-01T09:39:46Z
date_published: 2018-10-11T00:00:00Z
date_updated: 2023-08-07T10:56:26Z
day: '11'
doi: 10.1002/adma.201706750
extern: '1'
external_id:
  pmid:
  - '29520846'
intvolume: '        30'
issue: '41'
keyword:
- Mechanical Engineering
- Mechanics of Materials
- General Materials Science
language:
- iso: eng
month: '10'
oa_version: None
pmid: 1
publication: Advanced Materials
publication_identifier:
  eissn:
  - 1521-4095
  issn:
  - 0935-9648
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Dissipative self-assembly driven by the consumption of chemical fuels
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 30
year: '2018'
...
---
_id: '13376'
abstract:
- lang: eng
  text: Efficient molecular switching in confined spaces is critical for the successful
    development of artificial molecular machines. However, molecular switching events
    often entail large structural changes and therefore require conformational freedom,
    which is typically limited under confinement conditions. Here, we investigated
    the behavior of azobenzene—the key building block of light-controlled molecular
    machines—in a confined environment that is flexible and can adapt its shape to
    that of the bound guest. To this end, we encapsulated several structurally diverse
    azobenzenes within the cavity of a flexible, water-soluble coordination cage,
    and investigated their light-responsive behavior. Using UV/Vis absorption spectroscopy
    and a combination of NMR methods, we showed that each of the encapsulated azobenzenes
    exhibited distinct switching properties. An azobenzene forming a 1:1 host–guest
    inclusion complex could be efficiently photoisomerized in a reversible fashion.
    In contrast, successful switching in inclusion complexes incorporating two azobenzene
    guests was dependent on the availability of free cages in the system, and it involved
    reversible trafficking of azobenzene between the cages. In the absence of extra
    cages, photoswitching was either suppressed or it involved expulsion of azobenzene
    from the cage and consequently its precipitation from the solution. This finding
    was utilized to develop an information storage medium in which messages could
    be written and erased in a reversible fashion using light.
article_processing_charge: No
article_type: original
author:
- first_name: Dipak
  full_name: Samanta, Dipak
  last_name: Samanta
- first_name: Julius
  full_name: Gemen, Julius
  last_name: Gemen
- first_name: Zonglin
  full_name: Chu, Zonglin
  last_name: Chu
- first_name: Yael
  full_name: Diskin-Posner, Yael
  last_name: Diskin-Posner
- first_name: Linda J. W.
  full_name: Shimon, Linda J. W.
  last_name: Shimon
- first_name: Rafal
  full_name: Klajn, Rafal
  id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
  last_name: Klajn
citation:
  ama: Samanta D, Gemen J, Chu Z, Diskin-Posner Y, Shimon LJW, Klajn R. Reversible
    photoswitching of encapsulated azobenzenes in water. <i>Proceedings of the National
    Academy of Sciences</i>. 2018;115(38):9379-9384. doi:<a href="https://doi.org/10.1073/pnas.1712787115">10.1073/pnas.1712787115</a>
  apa: Samanta, D., Gemen, J., Chu, Z., Diskin-Posner, Y., Shimon, L. J. W., &#38;
    Klajn, R. (2018). Reversible photoswitching of encapsulated azobenzenes in water.
    <i>Proceedings of the National Academy of Sciences</i>. Proceedings of the National
    Academy of Sciences. <a href="https://doi.org/10.1073/pnas.1712787115">https://doi.org/10.1073/pnas.1712787115</a>
  chicago: Samanta, Dipak, Julius Gemen, Zonglin Chu, Yael Diskin-Posner, Linda J.
    W. Shimon, and Rafal Klajn. “Reversible Photoswitching of Encapsulated Azobenzenes
    in Water.” <i>Proceedings of the National Academy of Sciences</i>. Proceedings
    of the National Academy of Sciences, 2018. <a href="https://doi.org/10.1073/pnas.1712787115">https://doi.org/10.1073/pnas.1712787115</a>.
  ieee: D. Samanta, J. Gemen, Z. Chu, Y. Diskin-Posner, L. J. W. Shimon, and R. Klajn,
    “Reversible photoswitching of encapsulated azobenzenes in water,” <i>Proceedings
    of the National Academy of Sciences</i>, vol. 115, no. 38. Proceedings of the
    National Academy of Sciences, pp. 9379–9384, 2018.
  ista: Samanta D, Gemen J, Chu Z, Diskin-Posner Y, Shimon LJW, Klajn R. 2018. Reversible
    photoswitching of encapsulated azobenzenes in water. Proceedings of the National
    Academy of Sciences. 115(38), 9379–9384.
  mla: Samanta, Dipak, et al. “Reversible Photoswitching of Encapsulated Azobenzenes
    in Water.” <i>Proceedings of the National Academy of Sciences</i>, vol. 115, no.
    38, Proceedings of the National Academy of Sciences, 2018, pp. 9379–84, doi:<a
    href="https://doi.org/10.1073/pnas.1712787115">10.1073/pnas.1712787115</a>.
  short: D. Samanta, J. Gemen, Z. Chu, Y. Diskin-Posner, L.J.W. Shimon, R. Klajn,
    Proceedings of the National Academy of Sciences 115 (2018) 9379–9384.
date_created: 2023-08-01T09:40:00Z
date_published: 2018-05-01T00:00:00Z
date_updated: 2023-08-07T10:58:11Z
day: '01'
doi: 10.1073/pnas.1712787115
extern: '1'
external_id:
  pmid:
  - '29717041'
intvolume: '       115'
issue: '38'
keyword:
- Multidisciplinary
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1073/pnas.1712787115
month: '05'
oa: 1
oa_version: Published Version
page: 9379-9384
pmid: 1
publication: Proceedings of the National Academy of Sciences
publication_identifier:
  eissn:
  - 1091-6490
  issn:
  - 0027-8424
publication_status: published
publisher: Proceedings of the National Academy of Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: Reversible photoswitching of encapsulated azobenzenes in water
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 115
year: '2018'
...
---
_id: '13377'
abstract:
- lang: eng
  text: Confining organic molecules to the surfaces of inorganic nanoparticles can
    induce intermolecular interactions between them, which can affect the composition
    of the mixed self-assembled monolayers obtained by co-adsorption from solution
    of two different molecules. Two thiolated ligands (a dialkylviologen and a zwitterionic
    sulfobetaine) that can interact with each other electrostatically were coadsorbed
    onto gold nanoparticles. The nanoparticles favor a narrow range of ratios of these
    two molecules that is largely independent of the molar ratio in solution. Changing
    the solution molar ratio of the two ligands by a factor of 5 000 affects the on-nanoparticle
    ratio of these ligands by only threefold. This behavior is reminiscent of the
    formation of insoluble inorganic salts (such as AgCl), which similarly compensate
    positive and negative charges upon crystallizing. Our results pave the way towards
    developing well-defined hybrid organic–inorganic nanostructures.
article_processing_charge: No
article_type: original
author:
- first_name: Zonglin
  full_name: Chu, Zonglin
  last_name: Chu
- first_name: Yanxiao
  full_name: Han, Yanxiao
  last_name: Han
- first_name: Petr
  full_name: Král, Petr
  last_name: Král
- first_name: Rafal
  full_name: Klajn, Rafal
  id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
  last_name: Klajn
citation:
  ama: 'Chu Z, Han Y, Král P, Klajn R. “Precipitation on nanoparticles”: Attractive
    intermolecular interactions stabilize specific ligand ratios on the surfaces of
    nanoparticles. <i>Angewandte Chemie International Edition</i>. 2018;57(24):7023-7027.
    doi:<a href="https://doi.org/10.1002/anie.201800673">10.1002/anie.201800673</a>'
  apa: 'Chu, Z., Han, Y., Král, P., &#38; Klajn, R. (2018). “Precipitation on nanoparticles”:
    Attractive intermolecular interactions stabilize specific ligand ratios on the
    surfaces of nanoparticles. <i>Angewandte Chemie International Edition</i>. Wiley.
    <a href="https://doi.org/10.1002/anie.201800673">https://doi.org/10.1002/anie.201800673</a>'
  chicago: 'Chu, Zonglin, Yanxiao Han, Petr Král, and Rafal Klajn. “‘Precipitation
    on Nanoparticles’: Attractive Intermolecular Interactions Stabilize Specific Ligand
    Ratios on the Surfaces of Nanoparticles.” <i>Angewandte Chemie International Edition</i>.
    Wiley, 2018. <a href="https://doi.org/10.1002/anie.201800673">https://doi.org/10.1002/anie.201800673</a>.'
  ieee: 'Z. Chu, Y. Han, P. Král, and R. Klajn, “‘Precipitation on nanoparticles’:
    Attractive intermolecular interactions stabilize specific ligand ratios on the
    surfaces of nanoparticles,” <i>Angewandte Chemie International Edition</i>, vol.
    57, no. 24. Wiley, pp. 7023–7027, 2018.'
  ista: 'Chu Z, Han Y, Král P, Klajn R. 2018. “Precipitation on nanoparticles”: Attractive
    intermolecular interactions stabilize specific ligand ratios on the surfaces of
    nanoparticles. Angewandte Chemie International Edition. 57(24), 7023–7027.'
  mla: 'Chu, Zonglin, et al. “‘Precipitation on Nanoparticles’: Attractive Intermolecular
    Interactions Stabilize Specific Ligand Ratios on the Surfaces of Nanoparticles.”
    <i>Angewandte Chemie International Edition</i>, vol. 57, no. 24, Wiley, 2018,
    pp. 7023–27, doi:<a href="https://doi.org/10.1002/anie.201800673">10.1002/anie.201800673</a>.'
  short: Z. Chu, Y. Han, P. Král, R. Klajn, Angewandte Chemie International Edition
    57 (2018) 7023–7027.
date_created: 2023-08-01T09:40:16Z
date_published: 2018-06-11T00:00:00Z
date_updated: 2023-08-07T11:14:28Z
day: '11'
doi: 10.1002/anie.201800673
extern: '1'
external_id:
  pmid:
  - '29673022'
intvolume: '        57'
issue: '24'
keyword:
- General Chemistry
- Catalysis
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1002/anie.201800673
month: '06'
oa: 1
oa_version: Published Version
page: 7023-7027
pmid: 1
publication: Angewandte Chemie International Edition
publication_identifier:
  eissn:
  - 1521-3773
  issn:
  - 1433-7851
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: '“Precipitation on nanoparticles”: Attractive intermolecular interactions stabilize
  specific ligand ratios on the surfaces of nanoparticles'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 57
year: '2018'
...
---
_id: '13379'
article_number: '1700827'
article_processing_charge: No
article_type: letter_note
author:
- first_name: David
  full_name: Bléger, David
  last_name: Bléger
- first_name: Rafal
  full_name: Klajn, Rafal
  id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b
  last_name: Klajn
citation:
  ama: Bléger D, Klajn R. Integrating macromolecules with molecular switches. <i>Macromolecular
    Rapid Communications</i>. 2018;39(1). doi:<a href="https://doi.org/10.1002/marc.201700827">10.1002/marc.201700827</a>
  apa: Bléger, D., &#38; Klajn, R. (2018). Integrating macromolecules with molecular
    switches. <i>Macromolecular Rapid Communications</i>. Wiley. <a href="https://doi.org/10.1002/marc.201700827">https://doi.org/10.1002/marc.201700827</a>
  chicago: Bléger, David, and Rafal Klajn. “Integrating Macromolecules with Molecular
    Switches.” <i>Macromolecular Rapid Communications</i>. Wiley, 2018. <a href="https://doi.org/10.1002/marc.201700827">https://doi.org/10.1002/marc.201700827</a>.
  ieee: D. Bléger and R. Klajn, “Integrating macromolecules with molecular switches,”
    <i>Macromolecular Rapid Communications</i>, vol. 39, no. 1. Wiley, 2018.
  ista: Bléger D, Klajn R. 2018. Integrating macromolecules with molecular switches.
    Macromolecular Rapid Communications. 39(1), 1700827.
  mla: Bléger, David, and Rafal Klajn. “Integrating Macromolecules with Molecular
    Switches.” <i>Macromolecular Rapid Communications</i>, vol. 39, no. 1, 1700827,
    Wiley, 2018, doi:<a href="https://doi.org/10.1002/marc.201700827">10.1002/marc.201700827</a>.
  short: D. Bléger, R. Klajn, Macromolecular Rapid Communications 39 (2018).
date_created: 2023-08-01T09:40:48Z
date_published: 2018-01-08T00:00:00Z
date_updated: 2023-08-07T11:16:49Z
day: '08'
doi: 10.1002/marc.201700827
extern: '1'
external_id:
  pmid:
  - '29314396'
intvolume: '        39'
issue: '1'
keyword:
- Materials Chemistry
- Polymers and Plastics
- Organic Chemistry
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1002/marc.201700827
month: '01'
oa: 1
oa_version: Published Version
pmid: 1
publication: Macromolecular Rapid Communications
publication_identifier:
  eissn:
  - 1521-3927
  issn:
  - 1022-1336
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Integrating macromolecules with molecular switches
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 39
year: '2018'
...
---
_id: '134'
abstract:
- lang: eng
  text: "The current state of the art in real-time two-dimensional water wave simulation
    requires developers to choose between efficient Fourier-based methods, which lack
    interactions with moving obstacles, and finite-difference or finite element methods,
    which handle environmental interactions but are significantly more expensive.
    This paper attempts to bridge this long-standing gap between complexity and performance,
    by proposing a new wave simulation method that can faithfully simulate wave interactions
    with moving obstacles in real time while simultaneously preserving minute details
    and accommodating very large simulation domains.\r\n\r\nPrevious methods for simulating
    2D water waves directly compute the change in height of the water surface, a strategy
    which imposes limitations based on the CFL condition (fast moving waves require
    small time steps) and Nyquist's limit (small wave details require closely-spaced
    simulation variables). This paper proposes a novel wavelet transformation that
    discretizes the liquid motion in terms of amplitude-like functions that vary over
    space, frequency, and direction, effectively generalizing Fourier-based methods
    to handle local interactions. Because these new variables change much more slowly
    over space than the original water height function, our change of variables drastically
    reduces the limitations of the CFL condition and Nyquist limit, allowing us to
    simulate highly detailed water waves at very large visual resolutions. Our discretization
    is amenable to fast summation and easy to parallelize. We also present basic extensions
    like pre-computed wave paths and two-way solid fluid coupling. Finally, we argue
    that our discretization provides a convenient set of variables for artistic manipulation,
    which we illustrate with a novel wave-painting interface."
acknowledged_ssus:
- _id: ScienComp
alternative_title:
- SIGGRAPH
article_number: '94'
article_processing_charge: No
author:
- first_name: Stefan
  full_name: Jeschke, Stefan
  id: 44D6411A-F248-11E8-B48F-1D18A9856A87
  last_name: Jeschke
- first_name: Tomas
  full_name: Skrivan, Tomas
  id: 486A5A46-F248-11E8-B48F-1D18A9856A87
  last_name: Skrivan
- first_name: Matthias
  full_name: Mueller Fischer, Matthias
  last_name: Mueller Fischer
- first_name: Nuttapong
  full_name: Chentanez, Nuttapong
  last_name: Chentanez
- first_name: Miles
  full_name: Macklin, Miles
  last_name: Macklin
- first_name: Christopher J
  full_name: Wojtan, Christopher J
  id: 3C61F1D2-F248-11E8-B48F-1D18A9856A87
  last_name: Wojtan
  orcid: 0000-0001-6646-5546
citation:
  ama: Jeschke S, Skrivan T, Mueller Fischer M, Chentanez N, Macklin M, Wojtan C.
    Water surface wavelets. <i>ACM Transactions on Graphics</i>. 2018;37(4). doi:<a
    href="https://doi.org/10.1145/3197517.3201336">10.1145/3197517.3201336</a>
  apa: Jeschke, S., Skrivan, T., Mueller Fischer, M., Chentanez, N., Macklin, M.,
    &#38; Wojtan, C. (2018). Water surface wavelets. <i>ACM Transactions on Graphics</i>.
    ACM. <a href="https://doi.org/10.1145/3197517.3201336">https://doi.org/10.1145/3197517.3201336</a>
  chicago: Jeschke, Stefan, Tomas Skrivan, Matthias Mueller Fischer, Nuttapong Chentanez,
    Miles Macklin, and Chris Wojtan. “Water Surface Wavelets.” <i>ACM Transactions
    on Graphics</i>. ACM, 2018. <a href="https://doi.org/10.1145/3197517.3201336">https://doi.org/10.1145/3197517.3201336</a>.
  ieee: S. Jeschke, T. Skrivan, M. Mueller Fischer, N. Chentanez, M. Macklin, and
    C. Wojtan, “Water surface wavelets,” <i>ACM Transactions on Graphics</i>, vol.
    37, no. 4. ACM, 2018.
  ista: Jeschke S, Skrivan T, Mueller Fischer M, Chentanez N, Macklin M, Wojtan C.
    2018. Water surface wavelets. ACM Transactions on Graphics. 37(4), 94.
  mla: Jeschke, Stefan, et al. “Water Surface Wavelets.” <i>ACM Transactions on Graphics</i>,
    vol. 37, no. 4, 94, ACM, 2018, doi:<a href="https://doi.org/10.1145/3197517.3201336">10.1145/3197517.3201336</a>.
  short: S. Jeschke, T. Skrivan, M. Mueller Fischer, N. Chentanez, M. Macklin, C.
    Wojtan, ACM Transactions on Graphics 37 (2018).
date_created: 2018-12-11T11:44:48Z
date_published: 2018-07-30T00:00:00Z
date_updated: 2024-02-28T13:58:51Z
day: '30'
ddc:
- '000'
department:
- _id: ChWo
doi: 10.1145/3197517.3201336
ec_funded: 1
external_id:
  isi:
  - '000448185000055'
file:
- access_level: open_access
  checksum: db75ebabe2ec432bf41389e614d6ef62
  content_type: application/pdf
  creator: dernst
  date_created: 2018-12-18T09:59:23Z
  date_updated: 2020-07-14T12:44:45Z
  file_id: '5744'
  file_name: 2018_ACM_Jeschke.pdf
  file_size: 22185016
  relation: main_file
file_date_updated: 2020-07-14T12:44:45Z
has_accepted_license: '1'
intvolume: '        37'
isi: 1
issue: '4'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-sa/4.0/
month: '07'
oa: 1
oa_version: Published Version
project:
- _id: 2533E772-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '638176'
  name: Efficient Simulation of Natural Phenomena at Extremely Large Scales
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
publication: ACM Transactions on Graphics
publication_status: published
publisher: ACM
publist_id: '7789'
quality_controlled: '1'
related_material:
  link:
  - description: News on IST Homepage
    relation: press_release
    url: https://ist.ac.at/en/news/new-water-simulation-captures-small-details-even-in-large-scenes/
scopus_import: '1'
status: public
title: Water surface wavelets
tmp:
  image: /images/cc_by_nc_sa.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC
    BY-NC-SA 4.0)
  short: CC BY-NC-SA (4.0)
type: journal_article
user_id: 2EBD1598-F248-11E8-B48F-1D18A9856A87
volume: 37
year: '2018'
...
---
_id: '13473'
abstract:
- lang: eng
  text: Stripped-envelope stars form in binary systems after losing mass through Roche-lobe
    overflow. They bear astrophysical significance as sources of UV and ionizing radiation
    in older stellar populations and, if sufficiently massive, as stripped supernova
    progenitors. Binary evolutionary models predict that they are common, but only
    a handful of subdwarfs with B-type companions are known. The question is whether
    a large population of such systems has evaded detection as a result of biases,
    or whether the model predictions are wrong. We reanalyze the well-studied post-interaction
    binary φ Persei. Recently, new data have improved the orbital solution of the
    system, which contains an ~1.2M⊙ stripped-envelope star and a rapidly rotating
    ~9.6M⊙ Be star. We compare with an extensive grid of evolutionary models using
    a Bayesian approach and constrain the initial masses of the progenitor to 7.2
    ± 0.4M⊙ for the stripped star and 3.8 ± 0.4M⊙ for the Be star. The system must
    have evolved through near-conservative mass transfer. These findings are consistent
    with earlier studies. The age we obtain, 57 ± 9 Myr, is in excellent agreement
    with the age of the α Persei cluster. We note that neither star was initially
    massive enough to produce a core-collapse supernova, but mass exchange pushed
    the Be star above the mass threshold. We find that the subdwarf is overluminous
    for its mass by almost an order of magnitude, compared to the expectations for
    a helium core burning star. We can only reconcile this if the subdwarf resides
    in a late phase of helium shell burning, which lasts only 2–3% of the total lifetime
    as a subdwarf. Assuming continuous star formation implies that up to ~50 less
    evolved, dimmer subdwarfs exist for each system similar to φ Persei, but have
    evaded detection so far. Our findings can be interpreted as a strong indication
    that a substantial population of stripped-envelope stars indeed exists, but has
    so far evaded detection because of observational biases and lack of large-scale
    systematic searches.
article_number: A30
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: A.
  full_name: Schootemeijer, A.
  last_name: Schootemeijer
- first_name: Ylva Louise Linsdotter
  full_name: Götberg, Ylva Louise Linsdotter
  id: d0648d0c-0f64-11ee-a2e0-dd0faa2e4f7d
  last_name: Götberg
  orcid: 0000-0002-6960-6911
- first_name: S. E.
  full_name: de Mink, S. E.
  last_name: de Mink
- first_name: D.
  full_name: Gies, D.
  last_name: Gies
- first_name: E.
  full_name: Zapartas, E.
  last_name: Zapartas
citation:
  ama: Schootemeijer A, Götberg YLL, de Mink SE, Gies D, Zapartas E. Clues about the
    scarcity of stripped-envelope stars from the evolutionary state of the sdO+Be
    binary system φ Persei. <i>Astronomy &#38; Astrophysics</i>. 2018;615. doi:<a
    href="https://doi.org/10.1051/0004-6361/201731194">10.1051/0004-6361/201731194</a>
  apa: Schootemeijer, A., Götberg, Y. L. L., de Mink, S. E., Gies, D., &#38; Zapartas,
    E. (2018). Clues about the scarcity of stripped-envelope stars from the evolutionary
    state of the sdO+Be binary system φ Persei. <i>Astronomy &#38; Astrophysics</i>.
    EDP Sciences. <a href="https://doi.org/10.1051/0004-6361/201731194">https://doi.org/10.1051/0004-6361/201731194</a>
  chicago: Schootemeijer, A., Ylva Louise Linsdotter Götberg, S. E. de Mink, D. Gies,
    and E. Zapartas. “Clues about the Scarcity of Stripped-Envelope Stars from the
    Evolutionary State of the SdO+Be Binary System φ Persei.” <i>Astronomy &#38; Astrophysics</i>.
    EDP Sciences, 2018. <a href="https://doi.org/10.1051/0004-6361/201731194">https://doi.org/10.1051/0004-6361/201731194</a>.
  ieee: A. Schootemeijer, Y. L. L. Götberg, S. E. de Mink, D. Gies, and E. Zapartas,
    “Clues about the scarcity of stripped-envelope stars from the evolutionary state
    of the sdO+Be binary system φ Persei,” <i>Astronomy &#38; Astrophysics</i>, vol.
    615. EDP Sciences, 2018.
  ista: Schootemeijer A, Götberg YLL, de Mink SE, Gies D, Zapartas E. 2018. Clues
    about the scarcity of stripped-envelope stars from the evolutionary state of the
    sdO+Be binary system φ Persei. Astronomy &#38; Astrophysics. 615, A30.
  mla: Schootemeijer, A., et al. “Clues about the Scarcity of Stripped-Envelope Stars
    from the Evolutionary State of the SdO+Be Binary System φ Persei.” <i>Astronomy
    &#38; Astrophysics</i>, vol. 615, A30, EDP Sciences, 2018, doi:<a href="https://doi.org/10.1051/0004-6361/201731194">10.1051/0004-6361/201731194</a>.
  short: A. Schootemeijer, Y.L.L. Götberg, S.E. de Mink, D. Gies, E. Zapartas, Astronomy
    &#38; Astrophysics 615 (2018).
date_created: 2023-08-03T10:14:37Z
date_published: 2018-07-06T00:00:00Z
date_updated: 2023-08-09T12:22:52Z
day: '06'
doi: 10.1051/0004-6361/201731194
extern: '1'
external_id:
  arxiv:
  - '1803.02379'
intvolume: '       615'
keyword:
- Space and Planetary Science
- Astronomy and Astrophysics
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1051/0004-6361/201731194
month: '07'
oa: 1
oa_version: Published Version
publication: Astronomy & Astrophysics
publication_identifier:
  eissn:
  - 1432-0746
  issn:
  - 0004-6361
publication_status: published
publisher: EDP Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: Clues about the scarcity of stripped-envelope stars from the evolutionary state
  of the sdO+Be binary system φ Persei
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 615
year: '2018'
...
---
_id: '13474'
abstract:
- lang: eng
  text: Recent surveys of the Magellanic Clouds have revealed a subtype of Wolf–Rayet
    (WR) star with peculiar properties. WN3/O3 spectra exhibit both WR-like emission
    and O3 V-like absorption – but at lower luminosity than O3 V or WN stars. We examine
    the projected spatial distribution of WN3/O3 stars in the Large Magellanic Cloud
    as compared to O-type stars. Surprisingly, WN3/O3 stars are among the most isolated
    of all classes of massive stars; they have a distribution similar to red supergiants
    dominated by initial masses of 10–15 M⊙, and are far more dispersed than classical
    WR stars or luminous blue variables. Their lack of association with clusters of
    O-type stars suggests strongly that WN3/O3 stars are not the descendants of single
    massive stars (30 M⊙ or above). Instead, they are likely products of interacting
    binaries at lower initial mass (10–18 M⊙). Comparison with binary models suggests
    a probable origin with primaries in this mass range that were stripped of their
    H envelopes through non-conservative mass transfer by a low-mass secondary. We
    show that model spectra and positions on the Hertzsprung–Russell diagram for binary-stripped
    stars are consistent with WN3/O3 stars. Monitoring radial velocities with high-resolution
    spectra can test for low-mass companions or runaway velocities. With lower initial
    mass and environments that avoid very massive stars, the WN3/O3 stars fit expectations
    for progenitors of Type Ib and possibly Type Ibn supernovae.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Nathan
  full_name: Smith, Nathan
  last_name: Smith
- first_name: Ylva Louise Linsdotter
  full_name: Götberg, Ylva Louise Linsdotter
  id: d0648d0c-0f64-11ee-a2e0-dd0faa2e4f7d
  last_name: Götberg
  orcid: 0000-0002-6960-6911
- first_name: Selma E
  full_name: de Mink, Selma E
  last_name: de Mink
citation:
  ama: Smith N, Götberg YLL, de Mink SE. Extreme isolation of WN3/O3 stars and implications
    for their evolutionary origin as the elusive stripped binaries. <i>Monthly Notices
    of the Royal Astronomical Society</i>. 2018;475(1):772-782. doi:<a href="https://doi.org/10.1093/mnras/stx3181">10.1093/mnras/stx3181</a>
  apa: Smith, N., Götberg, Y. L. L., &#38; de Mink, S. E. (2018). Extreme isolation
    of WN3/O3 stars and implications for their evolutionary origin as the elusive
    stripped binaries. <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford
    University Press. <a href="https://doi.org/10.1093/mnras/stx3181">https://doi.org/10.1093/mnras/stx3181</a>
  chicago: Smith, Nathan, Ylva Louise Linsdotter Götberg, and Selma E de Mink. “Extreme
    Isolation of WN3/O3 Stars and Implications for Their Evolutionary Origin as the
    Elusive Stripped Binaries.” <i>Monthly Notices of the Royal Astronomical Society</i>.
    Oxford University Press, 2018. <a href="https://doi.org/10.1093/mnras/stx3181">https://doi.org/10.1093/mnras/stx3181</a>.
  ieee: N. Smith, Y. L. L. Götberg, and S. E. de Mink, “Extreme isolation of WN3/O3
    stars and implications for their evolutionary origin as the elusive stripped binaries,”
    <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 475, no. 1. Oxford
    University Press, pp. 772–782, 2018.
  ista: Smith N, Götberg YLL, de Mink SE. 2018. Extreme isolation of WN3/O3 stars
    and implications for their evolutionary origin as the elusive stripped binaries.
    Monthly Notices of the Royal Astronomical Society. 475(1), 772–782.
  mla: Smith, Nathan, et al. “Extreme Isolation of WN3/O3 Stars and Implications for
    Their Evolutionary Origin as the Elusive Stripped Binaries.” <i>Monthly Notices
    of the Royal Astronomical Society</i>, vol. 475, no. 1, Oxford University Press,
    2018, pp. 772–82, doi:<a href="https://doi.org/10.1093/mnras/stx3181">10.1093/mnras/stx3181</a>.
  short: N. Smith, Y.L.L. Götberg, S.E. de Mink, Monthly Notices of the Royal Astronomical
    Society 475 (2018) 772–782.
date_created: 2023-08-03T10:14:47Z
date_published: 2018-03-01T00:00:00Z
date_updated: 2023-08-09T12:17:34Z
day: '01'
doi: 10.1093/mnras/stx3181
extern: '1'
external_id:
  arxiv:
  - '1704.03516'
intvolume: '       475'
issue: '1'
keyword:
- Space and Planetary Science
- Astronomy and Astrophysics
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1093/mnras/stx3181
month: '03'
oa: 1
oa_version: Published Version
page: 772-782
publication: Monthly Notices of the Royal Astronomical Society
publication_identifier:
  eissn:
  - 1365-2966
  issn:
  - 0035-8711
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Extreme isolation of WN3/O3 stars and implications for their evolutionary origin
  as the elusive stripped binaries
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 475
year: '2018'
...
---
_id: '13475'
abstract:
- lang: eng
  text: Stars stripped of their hydrogen-rich envelope through interaction with a
    binary companion are generally not considered when accounting for ionizing radiation
    from stellar populations, despite the expectation that stripped stars emit hard
    ionizing radiation, form frequently, and live 10–100 times longer than single
    massive stars. We compute the first grid of evolutionary and spectral models specially
    made for stars stripped in binaries for a range of progenitor masses (2–20 M⊙)
    and metallicities ranging from solar to values representative for pop II stars.
    For stripped stars with masses in the range 0.3–7 M⊙, we find consistently high
    effective temperatures (20 000–100 000 K, increasing with mass), small radii (0.2–1
    R⊙), and high bolometric luminosities, comparable to that of their progenitor
    before stripping. The spectra show a continuous sequence that naturally bridges
    subdwarf-type stars at the low-mass end and Wolf-Rayet-like spectra at the high-mass
    end. For intermediate masses we find hybrid spectral classes showing a mixture
    of absorption and emission lines. These appear for stars with mass-loss rates
    of 10−8−10−6 M⊙ yr−1, which have semi-transparent atmospheres. At low metallicity,
    substantial hydrogen-rich layers are left at the surface and we predict spectra
    that resemble O-type stars instead. We obtain spectra undistinguishable from subdwarfs
    for stripped stars with masses up to 1.7 M⊙, which questions whether the widely
    adopted canonical value of 0.47 M⊙ is uniformly valid. Only a handful of stripped
    stars of intermediate mass have currently been identified observationally. Increasing
    this sample will provide necessary tests for the physics of interaction, internal
    mixing, and stellar winds. We use our model spectra to investigate the feasibility
    to detect stripped stars next to an optically bright companion and recommend systematic
    searches for their UV excess and possible emission lines, most notably HeII λ4686
    in the optical and HeII λ1640 in the UV. Our models are publicly available for
    further investigations or inclusion in spectral synthesis simulations.
article_number: A78
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Ylva Louise Linsdotter
  full_name: Götberg, Ylva Louise Linsdotter
  id: d0648d0c-0f64-11ee-a2e0-dd0faa2e4f7d
  last_name: Götberg
  orcid: 0000-0002-6960-6911
- first_name: S. E.
  full_name: de Mink, S. E.
  last_name: de Mink
- first_name: J. H.
  full_name: Groh, J. H.
  last_name: Groh
- first_name: T.
  full_name: Kupfer, T.
  last_name: Kupfer
- first_name: P. A.
  full_name: Crowther, P. A.
  last_name: Crowther
- first_name: E.
  full_name: Zapartas, E.
  last_name: Zapartas
- first_name: M.
  full_name: Renzo, M.
  last_name: Renzo
citation:
  ama: 'Götberg YLL, de Mink SE, Groh JH, et al. Spectral models for binary products:
    Unifying subdwarfs and Wolf-Rayet stars as a sequence of stripped-envelope stars.
    <i>Astronomy &#38;amp; Astrophysics</i>. 2018;615. doi:<a href="https://doi.org/10.1051/0004-6361/201732274">10.1051/0004-6361/201732274</a>'
  apa: 'Götberg, Y. L. L., de Mink, S. E., Groh, J. H., Kupfer, T., Crowther, P. A.,
    Zapartas, E., &#38; Renzo, M. (2018). Spectral models for binary products: Unifying
    subdwarfs and Wolf-Rayet stars as a sequence of stripped-envelope stars. <i>Astronomy
    &#38;amp; Astrophysics</i>. EDP Sciences. <a href="https://doi.org/10.1051/0004-6361/201732274">https://doi.org/10.1051/0004-6361/201732274</a>'
  chicago: 'Götberg, Ylva Louise Linsdotter, S. E. de Mink, J. H. Groh, T. Kupfer,
    P. A. Crowther, E. Zapartas, and M. Renzo. “Spectral Models for Binary Products:
    Unifying Subdwarfs and Wolf-Rayet Stars as a Sequence of Stripped-Envelope Stars.”
    <i>Astronomy &#38;amp; Astrophysics</i>. EDP Sciences, 2018. <a href="https://doi.org/10.1051/0004-6361/201732274">https://doi.org/10.1051/0004-6361/201732274</a>.'
  ieee: 'Y. L. L. Götberg <i>et al.</i>, “Spectral models for binary products: Unifying
    subdwarfs and Wolf-Rayet stars as a sequence of stripped-envelope stars,” <i>Astronomy
    &#38;amp; Astrophysics</i>, vol. 615. EDP Sciences, 2018.'
  ista: 'Götberg YLL, de Mink SE, Groh JH, Kupfer T, Crowther PA, Zapartas E, Renzo
    M. 2018. Spectral models for binary products: Unifying subdwarfs and Wolf-Rayet
    stars as a sequence of stripped-envelope stars. Astronomy &#38;amp; Astrophysics.
    615, A78.'
  mla: 'Götberg, Ylva Louise Linsdotter, et al. “Spectral Models for Binary Products:
    Unifying Subdwarfs and Wolf-Rayet Stars as a Sequence of Stripped-Envelope Stars.”
    <i>Astronomy &#38;amp; Astrophysics</i>, vol. 615, A78, EDP Sciences, 2018, doi:<a
    href="https://doi.org/10.1051/0004-6361/201732274">10.1051/0004-6361/201732274</a>.'
  short: Y.L.L. Götberg, S.E. de Mink, J.H. Groh, T. Kupfer, P.A. Crowther, E. Zapartas,
    M. Renzo, Astronomy &#38;amp; Astrophysics 615 (2018).
date_created: 2023-08-03T10:15:00Z
date_published: 2018-07-17T00:00:00Z
date_updated: 2023-08-09T11:22:17Z
day: '17'
doi: 10.1051/0004-6361/201732274
extern: '1'
external_id:
  arxiv:
  - '1802.03018'
intvolume: '       615'
keyword:
- Space and Planetary Science
- Astronomy and Astrophysics
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1051/0004-6361/201732274
month: '07'
oa: 1
oa_version: Published Version
publication: Astronomy &amp; Astrophysics
publication_identifier:
  eissn:
  - 1432-0746
  issn:
  - 0004-6361
publication_status: published
publisher: EDP Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Spectral models for binary products: Unifying subdwarfs and Wolf-Rayet stars
  as a sequence of stripped-envelope stars'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 615
year: '2018'
...
---
_id: '135'
abstract:
- lang: eng
  text: The Fluid Implicit Particle method (FLIP) reduces numerical dissipation by
    combining particles with grids. To improve performance, the subsequent narrow
    band FLIP method (NB‐FLIP) uses a FLIP‐based fluid simulation only near the liquid
    surface and a traditional grid‐based fluid simulation away from the surface. This
    spatially‐limited FLIP simulation significantly reduces the number of particles
    and alleviates a computational bottleneck. In this paper, we extend the NB‐FLIP
    idea even further, by allowing a simulation to transition between a FLIP‐like
    fluid simulation and a grid‐based simulation in arbitrary locations, not just
    near the surface. This approach leads to even more savings in memory and computation,
    because we can concentrate the particles only in areas where they are needed.
    More importantly, this new method allows us to seamlessly transition to smooth
    implicit surface geometry wherever the particle‐based simulation is unnecessary.
    Consequently, our method leads to a practical algorithm for avoiding the noisy
    surface artifacts associated with particle‐based liquid simulations, while simultaneously
    maintaining the benefits of a FLIP simulation in regions of dynamic motion.
alternative_title:
- Eurographics
article_processing_charge: No
article_type: original
author:
- first_name: Takahiro
  full_name: Sato, Takahiro
  last_name: Sato
- first_name: Christopher J
  full_name: Wojtan, Christopher J
  id: 3C61F1D2-F248-11E8-B48F-1D18A9856A87
  last_name: Wojtan
  orcid: 0000-0001-6646-5546
- first_name: Nils
  full_name: Thuerey, Nils
  last_name: Thuerey
- first_name: Takeo
  full_name: Igarashi, Takeo
  last_name: Igarashi
- first_name: Ryoichi
  full_name: Ando, Ryoichi
  last_name: Ando
citation:
  ama: Sato T, Wojtan C, Thuerey N, Igarashi T, Ando R. Extended narrow band FLIP
    for liquid simulations. <i>Computer Graphics Forum</i>. 2018;37(2):169-177. doi:<a
    href="https://doi.org/10.1111/cgf.13351">10.1111/cgf.13351</a>
  apa: Sato, T., Wojtan, C., Thuerey, N., Igarashi, T., &#38; Ando, R. (2018). Extended
    narrow band FLIP for liquid simulations. <i>Computer Graphics Forum</i>. Wiley.
    <a href="https://doi.org/10.1111/cgf.13351">https://doi.org/10.1111/cgf.13351</a>
  chicago: Sato, Takahiro, Chris Wojtan, Nils Thuerey, Takeo Igarashi, and Ryoichi
    Ando. “Extended Narrow Band FLIP for Liquid Simulations.” <i>Computer Graphics
    Forum</i>. Wiley, 2018. <a href="https://doi.org/10.1111/cgf.13351">https://doi.org/10.1111/cgf.13351</a>.
  ieee: T. Sato, C. Wojtan, N. Thuerey, T. Igarashi, and R. Ando, “Extended narrow
    band FLIP for liquid simulations,” <i>Computer Graphics Forum</i>, vol. 37, no.
    2. Wiley, pp. 169–177, 2018.
  ista: Sato T, Wojtan C, Thuerey N, Igarashi T, Ando R. 2018. Extended narrow band
    FLIP for liquid simulations. Computer Graphics Forum. 37(2), 169–177.
  mla: Sato, Takahiro, et al. “Extended Narrow Band FLIP for Liquid Simulations.”
    <i>Computer Graphics Forum</i>, vol. 37, no. 2, Wiley, 2018, pp. 169–77, doi:<a
    href="https://doi.org/10.1111/cgf.13351">10.1111/cgf.13351</a>.
  short: T. Sato, C. Wojtan, N. Thuerey, T. Igarashi, R. Ando, Computer Graphics Forum
    37 (2018) 169–177.
date_created: 2018-12-11T11:44:49Z
date_published: 2018-05-22T00:00:00Z
date_updated: 2023-09-11T14:00:26Z
day: '22'
ddc:
- '006'
department:
- _id: ChWo
doi: 10.1111/cgf.13351
ec_funded: 1
external_id:
  isi:
  - '000434085600016'
file:
- access_level: open_access
  checksum: 8edb90da8a72395eb5d970580e0925b6
  content_type: application/pdf
  creator: wojtan
  date_created: 2020-10-08T08:38:23Z
  date_updated: 2020-10-08T08:38:23Z
  file_id: '8627'
  file_name: exnbflip.pdf
  file_size: 54309947
  relation: main_file
  success: 1
file_date_updated: 2020-10-08T08:38:23Z
has_accepted_license: '1'
intvolume: '        37'
isi: 1
issue: '2'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Submitted Version
page: 169 - 177
project:
- _id: 2533E772-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '638176'
  name: Efficient Simulation of Natural Phenomena at Extremely Large Scales
publication: Computer Graphics Forum
publication_identifier:
  issn:
  - 0167-7055
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Extended narrow band FLIP for liquid simulations
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 37
year: '2018'
...
---
_id: '136'
abstract:
- lang: eng
  text: Recent studies suggest that unstable, nonchaotic solutions of the Navier-Stokes
    equation may provide deep insights into fluid turbulence. In this article, we
    present a combined experimental and numerical study exploring the dynamical role
    of unstable equilibrium solutions and their invariant manifolds in a weakly turbulent,
    electromagnetically driven, shallow fluid layer. Identifying instants when turbulent
    evolution slows down, we compute 31 unstable equilibria of a realistic two-dimensional
    model of the flow. We establish the dynamical relevance of these unstable equilibria
    by showing that they are closely visited by the turbulent flow. We also establish
    the dynamical relevance of unstable manifolds by verifying that they are shadowed
    by turbulent trajectories departing from the neighborhoods of unstable equilibria
    over large distances in state space.
article_processing_charge: No
arxiv: 1
author:
- first_name: Balachandra
  full_name: Suri, Balachandra
  id: 47A5E706-F248-11E8-B48F-1D18A9856A87
  last_name: Suri
- first_name: Jeffrey
  full_name: Tithof, Jeffrey
  last_name: Tithof
- first_name: Roman
  full_name: Grigoriev, Roman
  last_name: Grigoriev
- first_name: Michael
  full_name: Schatz, Michael
  last_name: Schatz
citation:
  ama: Suri B, Tithof J, Grigoriev R, Schatz M. Unstable equilibria and invariant
    manifolds in quasi-two-dimensional Kolmogorov-like flow. <i>Physical Review E</i>.
    2018;98(2). doi:<a href="https://doi.org/10.1103/PhysRevE.98.023105">10.1103/PhysRevE.98.023105</a>
  apa: Suri, B., Tithof, J., Grigoriev, R., &#38; Schatz, M. (2018). Unstable equilibria
    and invariant manifolds in quasi-two-dimensional Kolmogorov-like flow. <i>Physical
    Review E</i>. American Physical Society. <a href="https://doi.org/10.1103/PhysRevE.98.023105">https://doi.org/10.1103/PhysRevE.98.023105</a>
  chicago: Suri, Balachandra, Jeffrey Tithof, Roman Grigoriev, and Michael Schatz.
    “Unstable Equilibria and Invariant Manifolds in Quasi-Two-Dimensional Kolmogorov-like
    Flow.” <i>Physical Review E</i>. American Physical Society, 2018. <a href="https://doi.org/10.1103/PhysRevE.98.023105">https://doi.org/10.1103/PhysRevE.98.023105</a>.
  ieee: B. Suri, J. Tithof, R. Grigoriev, and M. Schatz, “Unstable equilibria and
    invariant manifolds in quasi-two-dimensional Kolmogorov-like flow,” <i>Physical
    Review E</i>, vol. 98, no. 2. American Physical Society, 2018.
  ista: Suri B, Tithof J, Grigoriev R, Schatz M. 2018. Unstable equilibria and invariant
    manifolds in quasi-two-dimensional Kolmogorov-like flow. Physical Review E. 98(2).
  mla: Suri, Balachandra, et al. “Unstable Equilibria and Invariant Manifolds in Quasi-Two-Dimensional
    Kolmogorov-like Flow.” <i>Physical Review E</i>, vol. 98, no. 2, American Physical
    Society, 2018, doi:<a href="https://doi.org/10.1103/PhysRevE.98.023105">10.1103/PhysRevE.98.023105</a>.
  short: B. Suri, J. Tithof, R. Grigoriev, M. Schatz, Physical Review E 98 (2018).
date_created: 2018-12-11T11:44:49Z
date_published: 2018-08-13T00:00:00Z
date_updated: 2023-10-10T13:29:10Z
day: '13'
department:
- _id: BjHo
doi: 10.1103/PhysRevE.98.023105
external_id:
  arxiv:
  - '1808.02088'
  isi:
  - '000441466800010'
intvolume: '        98'
isi: 1
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1808.02088
month: '08'
oa: 1
oa_version: Submitted Version
publication: Physical Review E
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Unstable equilibria and invariant manifolds in quasi-two-dimensional Kolmogorov-like
  flow
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 98
year: '2018'
...
---
_id: '137'
abstract:
- lang: eng
  text: Fluorescent sensors are an essential part of the experimental toolbox of the
    life sciences, where they are used ubiquitously to visualize intra- and extracellular
    signaling. In the brain, optical neurotransmitter sensors can shed light on temporal
    and spatial aspects of signal transmission by directly observing, for instance,
    neurotransmitter release and spread. Here we report the development and application
    of the first optical sensor for the amino acid glycine, which is both an inhibitory
    neurotransmitter and a co-agonist of the N-methyl-d-aspartate receptors (NMDARs)
    involved in synaptic plasticity. Computational design of a glycine-specific binding
    protein allowed us to produce the optical glycine FRET sensor (GlyFS), which can
    be used with single and two-photon excitation fluorescence microscopy. We took
    advantage of this newly developed sensor to test predictions about the uneven
    spatial distribution of glycine in extracellular space and to demonstrate that
    extracellular glycine levels are controlled by plasticity-inducing stimuli.
article_processing_charge: No
article_type: original
author:
- first_name: William
  full_name: Zhang, William
  last_name: Zhang
- first_name: Michel
  full_name: Herde, Michel
  last_name: Herde
- first_name: Joshua
  full_name: Mitchell, Joshua
  last_name: Mitchell
- first_name: Jason
  full_name: Whitfield, Jason
  last_name: Whitfield
- first_name: Andreas
  full_name: Wulff, Andreas
  last_name: Wulff
- first_name: Vanessa
  full_name: Vongsouthi, Vanessa
  last_name: Vongsouthi
- first_name: Inmaculada
  full_name: Sanchez Romero, Inmaculada
  id: 3D9C5D30-F248-11E8-B48F-1D18A9856A87
  last_name: Sanchez Romero
- first_name: Polina
  full_name: Gulakova, Polina
  last_name: Gulakova
- first_name: Daniel
  full_name: Minge, Daniel
  last_name: Minge
- first_name: Björn
  full_name: Breithausen, Björn
  last_name: Breithausen
- first_name: Susanne
  full_name: Schoch, Susanne
  last_name: Schoch
- first_name: Harald L
  full_name: Janovjak, Harald L
  id: 33BA6C30-F248-11E8-B48F-1D18A9856A87
  last_name: Janovjak
  orcid: 0000-0002-8023-9315
- first_name: Colin
  full_name: Jackson, Colin
  last_name: Jackson
- first_name: Christian
  full_name: Henneberger, Christian
  last_name: Henneberger
citation:
  ama: Zhang W, Herde M, Mitchell J, et al. Monitoring hippocampal glycine with the
    computationally designed optical sensor GlyFS. <i>Nature Chemical Biology</i>.
    2018;14(9):861-869. doi:<a href="https://doi.org/10.1038/s41589-018-0108-2">10.1038/s41589-018-0108-2</a>
  apa: Zhang, W., Herde, M., Mitchell, J., Whitfield, J., Wulff, A., Vongsouthi, V.,
    … Henneberger, C. (2018). Monitoring hippocampal glycine with the computationally
    designed optical sensor GlyFS. <i>Nature Chemical Biology</i>. Nature Publishing
    Group. <a href="https://doi.org/10.1038/s41589-018-0108-2">https://doi.org/10.1038/s41589-018-0108-2</a>
  chicago: Zhang, William, Michel Herde, Joshua Mitchell, Jason Whitfield, Andreas
    Wulff, Vanessa Vongsouthi, Inmaculada Sanchez-Romero, et al. “Monitoring Hippocampal
    Glycine with the Computationally Designed Optical Sensor GlyFS.” <i>Nature Chemical
    Biology</i>. Nature Publishing Group, 2018. <a href="https://doi.org/10.1038/s41589-018-0108-2">https://doi.org/10.1038/s41589-018-0108-2</a>.
  ieee: W. Zhang <i>et al.</i>, “Monitoring hippocampal glycine with the computationally
    designed optical sensor GlyFS,” <i>Nature Chemical Biology</i>, vol. 14, no. 9.
    Nature Publishing Group, pp. 861–869, 2018.
  ista: Zhang W, Herde M, Mitchell J, Whitfield J, Wulff A, Vongsouthi V, Sanchez-Romero
    I, Gulakova P, Minge D, Breithausen B, Schoch S, Janovjak HL, Jackson C, Henneberger
    C. 2018. Monitoring hippocampal glycine with the computationally designed optical
    sensor GlyFS. Nature Chemical Biology. 14(9), 861–869.
  mla: Zhang, William, et al. “Monitoring Hippocampal Glycine with the Computationally
    Designed Optical Sensor GlyFS.” <i>Nature Chemical Biology</i>, vol. 14, no. 9,
    Nature Publishing Group, 2018, pp. 861–69, doi:<a href="https://doi.org/10.1038/s41589-018-0108-2">10.1038/s41589-018-0108-2</a>.
  short: W. Zhang, M. Herde, J. Mitchell, J. Whitfield, A. Wulff, V. Vongsouthi, I.
    Sanchez-Romero, P. Gulakova, D. Minge, B. Breithausen, S. Schoch, H.L. Janovjak,
    C. Jackson, C. Henneberger, Nature Chemical Biology 14 (2018) 861–869.
date_created: 2018-12-11T11:44:49Z
date_published: 2018-07-30T00:00:00Z
date_updated: 2023-09-13T08:58:05Z
day: '30'
department:
- _id: HaJa
doi: 10.1038/s41589-018-0108-2
external_id:
  isi:
  - '000442174500013'
  pmid:
  - '30061718 '
intvolume: '        14'
isi: 1
issue: '9'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pubmed/30061718
month: '07'
oa: 1
oa_version: Submitted Version
page: 861 - 869
pmid: 1
project:
- _id: 255BFFFA-B435-11E9-9278-68D0E5697425
  grant_number: RGY0084/2012
  name: In situ real-time imaging of neurotransmitter signaling using designer optical
    sensors (HFSP Young Investigator)
publication: Nature Chemical Biology
publication_status: published
publisher: Nature Publishing Group
publist_id: '7786'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Monitoring hippocampal glycine with the computationally designed optical sensor
  GlyFS
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 14
year: '2018'
...
