---
_id: '8438'
article_processing_charge: No
article_type: letter_note
author:
- first_name: Vilius
full_name: Kurauskas, Vilius
last_name: Kurauskas
- first_name: Audrey
full_name: Hessel, Audrey
last_name: Hessel
- first_name: François
full_name: Dehez, François
last_name: Dehez
- first_name: Christophe
full_name: Chipot, Christophe
last_name: Chipot
- first_name: Beate
full_name: Bersch, Beate
last_name: Bersch
- first_name: Paul
full_name: Schanda, Paul
id: 7B541462-FAF6-11E9-A490-E8DFE5697425
last_name: Schanda
orcid: 0000-0002-9350-7606
citation:
ama: Kurauskas V, Hessel A, Dehez F, Chipot C, Bersch B, Schanda P. Dynamics and
interactions of AAC3 in DPC are not functionally relevant. Nature Structural
& Molecular Biology. 2018;25(9):745-747. doi:10.1038/s41594-018-0127-4
apa: Kurauskas, V., Hessel, A., Dehez, F., Chipot, C., Bersch, B., & Schanda,
P. (2018). Dynamics and interactions of AAC3 in DPC are not functionally relevant.
Nature Structural & Molecular Biology. Springer Nature. https://doi.org/10.1038/s41594-018-0127-4
chicago: Kurauskas, Vilius, Audrey Hessel, François Dehez, Christophe Chipot, Beate
Bersch, and Paul Schanda. “Dynamics and Interactions of AAC3 in DPC Are Not Functionally
Relevant.” Nature Structural & Molecular Biology. Springer Nature,
2018. https://doi.org/10.1038/s41594-018-0127-4.
ieee: V. Kurauskas, A. Hessel, F. Dehez, C. Chipot, B. Bersch, and P. Schanda, “Dynamics
and interactions of AAC3 in DPC are not functionally relevant,” Nature Structural
& Molecular Biology, vol. 25, no. 9. Springer Nature, pp. 745–747, 2018.
ista: Kurauskas V, Hessel A, Dehez F, Chipot C, Bersch B, Schanda P. 2018. Dynamics
and interactions of AAC3 in DPC are not functionally relevant. Nature Structural
& Molecular Biology. 25(9), 745–747.
mla: Kurauskas, Vilius, et al. “Dynamics and Interactions of AAC3 in DPC Are Not
Functionally Relevant.” Nature Structural & Molecular Biology, vol.
25, no. 9, Springer Nature, 2018, pp. 745–47, doi:10.1038/s41594-018-0127-4.
short: V. Kurauskas, A. Hessel, F. Dehez, C. Chipot, B. Bersch, P. Schanda, Nature
Structural & Molecular Biology 25 (2018) 745–747.
date_created: 2020-09-18T10:04:59Z
date_published: 2018-09-03T00:00:00Z
date_updated: 2021-01-12T08:19:16Z
day: '03'
doi: 10.1038/s41594-018-0127-4
extern: '1'
intvolume: ' 25'
issue: '9'
keyword:
- Molecular Biology
- Structural Biology
language:
- iso: eng
month: '09'
oa_version: None
page: 745-747
publication: Nature Structural & Molecular Biology
publication_identifier:
issn:
- 1545-9993
- 1545-9985
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Dynamics and interactions of AAC3 in DPC are not functionally relevant
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 25
year: '2018'
...
---
_id: '8439'
abstract:
- lang: eng
text: Lipopolysaccharides (LPS) are complex glycolipids forming the outside layer
of Gram-negative bacteria. Their hydrophobic and heterogeneous nature greatly
hampers their structural study in an environment similar to the bacterial surface.
We have studied LPS purified from E. coli and pathogenic P. aeruginosa with long
O-antigen polysaccharides assembled in solution as vesicles or elongated micelles.
Solid-state NMR with magic-angle spinning permitted the identification of NMR
signals arising from regions with different flexibilities in the LPS, from the
lipid components to the O-antigen polysaccharides. Atomic scale data on the LPS
enabled the study of the interaction of gentamicin antibiotic bound to P. aeruginosa
LPS, for which we could confirm that a specific oligosaccharide is involved in
the antibiotic binding. The possibility to study LPS alone and bound to a ligand
when it is assembled in membrane-like structures opens great prospects for the
investigation of proteins and antibiotics that specifically target such an important
molecule at the surface of Gram-negative bacteria.
article_processing_charge: No
article_type: original
author:
- first_name: Cedric
full_name: Laguri, Cedric
last_name: Laguri
- first_name: Alba
full_name: Silipo, Alba
last_name: Silipo
- first_name: Alessandra M.
full_name: Martorana, Alessandra M.
last_name: Martorana
- first_name: Paul
full_name: Schanda, Paul
id: 7B541462-FAF6-11E9-A490-E8DFE5697425
last_name: Schanda
orcid: 0000-0002-9350-7606
- first_name: Roberta
full_name: Marchetti, Roberta
last_name: Marchetti
- first_name: Alessandra
full_name: Polissi, Alessandra
last_name: Polissi
- first_name: Antonio
full_name: Molinaro, Antonio
last_name: Molinaro
- first_name: Jean-Pierre
full_name: Simorre, Jean-Pierre
last_name: Simorre
citation:
ama: Laguri C, Silipo A, Martorana AM, et al. Solid state NMR studies of intact
lipopolysaccharide endotoxin. ACS Chemical Biology. 2018;13(8):2106-2113.
doi:10.1021/acschembio.8b00271
apa: Laguri, C., Silipo, A., Martorana, A. M., Schanda, P., Marchetti, R., Polissi,
A., … Simorre, J.-P. (2018). Solid state NMR studies of intact lipopolysaccharide
endotoxin. ACS Chemical Biology. American Chemical Society. https://doi.org/10.1021/acschembio.8b00271
chicago: Laguri, Cedric, Alba Silipo, Alessandra M. Martorana, Paul Schanda, Roberta
Marchetti, Alessandra Polissi, Antonio Molinaro, and Jean-Pierre Simorre. “Solid
State NMR Studies of Intact Lipopolysaccharide Endotoxin.” ACS Chemical Biology.
American Chemical Society, 2018. https://doi.org/10.1021/acschembio.8b00271.
ieee: C. Laguri et al., “Solid state NMR studies of intact lipopolysaccharide
endotoxin,” ACS Chemical Biology, vol. 13, no. 8. American Chemical Society,
pp. 2106–2113, 2018.
ista: Laguri C, Silipo A, Martorana AM, Schanda P, Marchetti R, Polissi A, Molinaro
A, Simorre J-P. 2018. Solid state NMR studies of intact lipopolysaccharide endotoxin.
ACS Chemical Biology. 13(8), 2106–2113.
mla: Laguri, Cedric, et al. “Solid State NMR Studies of Intact Lipopolysaccharide
Endotoxin.” ACS Chemical Biology, vol. 13, no. 8, American Chemical Society,
2018, pp. 2106–13, doi:10.1021/acschembio.8b00271.
short: C. Laguri, A. Silipo, A.M. Martorana, P. Schanda, R. Marchetti, A. Polissi,
A. Molinaro, J.-P. Simorre, ACS Chemical Biology 13 (2018) 2106–2113.
date_created: 2020-09-18T10:05:09Z
date_published: 2018-07-02T00:00:00Z
date_updated: 2021-01-12T08:19:16Z
day: '02'
doi: 10.1021/acschembio.8b00271
extern: '1'
intvolume: ' 13'
issue: '8'
keyword:
- Molecular Medicine
- Biochemistry
- General Medicine
language:
- iso: eng
month: '07'
oa_version: None
page: 2106-2113
publication: ACS Chemical Biology
publication_identifier:
issn:
- 1554-8929
- 1554-8937
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
status: public
title: Solid state NMR studies of intact lipopolysaccharide endotoxin
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 13
year: '2018'
...
---
_id: '8440'
abstract:
- lang: eng
text: Mycobacterium tuberculosis can remain dormant in the host, an ability that
explains the failure of many current tuberculosis treatments. Recently, the natural
products cyclomarin, ecumicin, and lassomycin have been shown to efficiently kill
Mycobacterium tuberculosis persisters. Their target is the N-terminal domain of
the hexameric AAA+ ATPase ClpC1, which recognizes, unfolds, and translocates protein
substrates, such as proteins containing phosphorylated arginine residues, to the
ClpP1P2 protease for degradation. Surprisingly, these antibiotics do not inhibit
ClpC1 ATPase activity, and how they cause cell death is still unclear. Here, using
NMR and small-angle X-ray scattering, we demonstrate that arginine-phosphate binding
to the ClpC1 N-terminal domain induces millisecond dynamics. We show that these
dynamics are caused by conformational changes and do not result from unfolding
or oligomerization of this domain. Cyclomarin binding to this domain specifically
blocked these N-terminal dynamics. On the basis of these results, we propose a
mechanism of action involving cyclomarin-induced restriction of ClpC1 dynamics,
which modulates the chaperone enzymatic activity leading eventually to cell death.
article_processing_charge: No
article_type: original
author:
- first_name: Katharina
full_name: Weinhäupl, Katharina
last_name: Weinhäupl
- first_name: Martha
full_name: Brennich, Martha
last_name: Brennich
- first_name: Uli
full_name: Kazmaier, Uli
last_name: Kazmaier
- first_name: Joel
full_name: Lelievre, Joel
last_name: Lelievre
- first_name: Lluis
full_name: Ballell, Lluis
last_name: Ballell
- first_name: Alfred
full_name: Goldberg, Alfred
last_name: Goldberg
- first_name: Paul
full_name: Schanda, Paul
id: 7B541462-FAF6-11E9-A490-E8DFE5697425
last_name: Schanda
orcid: 0000-0002-9350-7606
- first_name: Hugo
full_name: Fraga, Hugo
last_name: Fraga
citation:
ama: Weinhäupl K, Brennich M, Kazmaier U, et al. The antibiotic cyclomarin blocks
arginine-phosphate–induced millisecond dynamics in the N-terminal domain of ClpC1
from Mycobacterium tuberculosis. Journal of Biological Chemistry. 2018;293(22):8379-8393.
doi:10.1074/jbc.ra118.002251
apa: Weinhäupl, K., Brennich, M., Kazmaier, U., Lelievre, J., Ballell, L., Goldberg,
A., … Fraga, H. (2018). The antibiotic cyclomarin blocks arginine-phosphate–induced
millisecond dynamics in the N-terminal domain of ClpC1 from Mycobacterium tuberculosis.
Journal of Biological Chemistry. American Society for Biochemistry &
Molecular Biology. https://doi.org/10.1074/jbc.ra118.002251
chicago: Weinhäupl, Katharina, Martha Brennich, Uli Kazmaier, Joel Lelievre, Lluis
Ballell, Alfred Goldberg, Paul Schanda, and Hugo Fraga. “The Antibiotic Cyclomarin
Blocks Arginine-Phosphate–Induced Millisecond Dynamics in the N-Terminal Domain
of ClpC1 from Mycobacterium Tuberculosis.” Journal of Biological Chemistry.
American Society for Biochemistry & Molecular Biology, 2018. https://doi.org/10.1074/jbc.ra118.002251.
ieee: K. Weinhäupl et al., “The antibiotic cyclomarin blocks arginine-phosphate–induced
millisecond dynamics in the N-terminal domain of ClpC1 from Mycobacterium tuberculosis,”
Journal of Biological Chemistry, vol. 293, no. 22. American Society for
Biochemistry & Molecular Biology, pp. 8379–8393, 2018.
ista: Weinhäupl K, Brennich M, Kazmaier U, Lelievre J, Ballell L, Goldberg A, Schanda
P, Fraga H. 2018. The antibiotic cyclomarin blocks arginine-phosphate–induced
millisecond dynamics in the N-terminal domain of ClpC1 from Mycobacterium tuberculosis.
Journal of Biological Chemistry. 293(22), 8379–8393.
mla: Weinhäupl, Katharina, et al. “The Antibiotic Cyclomarin Blocks Arginine-Phosphate–Induced
Millisecond Dynamics in the N-Terminal Domain of ClpC1 from Mycobacterium Tuberculosis.”
Journal of Biological Chemistry, vol. 293, no. 22, American Society for
Biochemistry & Molecular Biology, 2018, pp. 8379–93, doi:10.1074/jbc.ra118.002251.
short: K. Weinhäupl, M. Brennich, U. Kazmaier, J. Lelievre, L. Ballell, A. Goldberg,
P. Schanda, H. Fraga, Journal of Biological Chemistry 293 (2018) 8379–8393.
date_created: 2020-09-18T10:05:18Z
date_published: 2018-06-01T00:00:00Z
date_updated: 2021-01-12T08:19:17Z
day: '01'
doi: 10.1074/jbc.ra118.002251
extern: '1'
intvolume: ' 293'
issue: '22'
keyword:
- Cell Biology
- Biochemistry
- Molecular Biology
language:
- iso: eng
month: '06'
oa_version: None
page: 8379-8393
publication: Journal of Biological Chemistry
publication_identifier:
issn:
- 0021-9258
- 1083-351X
publication_status: published
publisher: American Society for Biochemistry & Molecular Biology
quality_controlled: '1'
status: public
title: The antibiotic cyclomarin blocks arginine-phosphate–induced millisecond dynamics
in the N-terminal domain of ClpC1 from Mycobacterium tuberculosis
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 293
year: '2018'
...
---
_id: '8441'
abstract:
- lang: eng
text: Solid-state near-rotary-resonance measurements of the spin–lattice relaxation
rate in the rotating frame (R1ρ) is a powerful NMR technique for studying molecular
dynamics in the microsecond time scale. The small difference between the spin-lock
(SL) and magic-angle-spinning (MAS) frequencies allows sampling very slow motions,
at the same time it brings up some methodological challenges. In this work, several
issues affecting correct measurements and analysis of 15N R1ρ data are considered
in detail. Among them are signal amplitude as a function of the difference between
SL and MAS frequencies, “dead time” in the initial part of the relaxation decay
caused by transient spin-dynamic oscillations, measurements under HORROR condition
and proper treatment of the multi-exponential relaxation decays. The multiple
15N R1ρ measurements at different SL fields and temperatures have been conducted
in 1D mode (i.e. without site-specific resolution) for a set of four different
microcrystalline protein samples (GB1, SH3, MPD-ubiquitin and cubic-PEG-ubiquitin)
to study the overall protein rocking in a crystal. While the amplitude of this
motion varies very significantly, its correlation time for all four sample is
practically the same, 30–50 μs. The amplitude of the rocking motion correlates
with the packing density of a protein crystal. It has been suggested that the
rocking motion is not diffusive but likely a jump-like dynamic process.
article_processing_charge: No
article_type: original
author:
- first_name: Alexey
full_name: Krushelnitsky, Alexey
last_name: Krushelnitsky
- first_name: Diego
full_name: Gauto, Diego
last_name: Gauto
- first_name: Diana C.
full_name: Rodriguez Camargo, Diana C.
last_name: Rodriguez Camargo
- first_name: Paul
full_name: Schanda, Paul
id: 7B541462-FAF6-11E9-A490-E8DFE5697425
last_name: Schanda
orcid: 0000-0002-9350-7606
- first_name: Kay
full_name: Saalwächter, Kay
last_name: Saalwächter
citation:
ama: 'Krushelnitsky A, Gauto D, Rodriguez Camargo DC, Schanda P, Saalwächter K.
Microsecond motions probed by near-rotary-resonance R1ρ 15N MAS NMR experiments:
The model case of protein overall-rocking in crystals. Journal of Biomolecular
NMR. 2018;71(1):53-67. doi:10.1007/s10858-018-0191-4'
apa: 'Krushelnitsky, A., Gauto, D., Rodriguez Camargo, D. C., Schanda, P., &
Saalwächter, K. (2018). Microsecond motions probed by near-rotary-resonance R1ρ
15N MAS NMR experiments: The model case of protein overall-rocking in crystals.
Journal of Biomolecular NMR. Springer Nature. https://doi.org/10.1007/s10858-018-0191-4'
chicago: 'Krushelnitsky, Alexey, Diego Gauto, Diana C. Rodriguez Camargo, Paul Schanda,
and Kay Saalwächter. “Microsecond Motions Probed by Near-Rotary-Resonance R1ρ
15N MAS NMR Experiments: The Model Case of Protein Overall-Rocking in Crystals.”
Journal of Biomolecular NMR. Springer Nature, 2018. https://doi.org/10.1007/s10858-018-0191-4.'
ieee: 'A. Krushelnitsky, D. Gauto, D. C. Rodriguez Camargo, P. Schanda, and K. Saalwächter,
“Microsecond motions probed by near-rotary-resonance R1ρ 15N MAS NMR experiments:
The model case of protein overall-rocking in crystals,” Journal of Biomolecular
NMR, vol. 71, no. 1. Springer Nature, pp. 53–67, 2018.'
ista: 'Krushelnitsky A, Gauto D, Rodriguez Camargo DC, Schanda P, Saalwächter K.
2018. Microsecond motions probed by near-rotary-resonance R1ρ 15N MAS NMR experiments:
The model case of protein overall-rocking in crystals. Journal of Biomolecular
NMR. 71(1), 53–67.'
mla: 'Krushelnitsky, Alexey, et al. “Microsecond Motions Probed by Near-Rotary-Resonance
R1ρ 15N MAS NMR Experiments: The Model Case of Protein Overall-Rocking in Crystals.”
Journal of Biomolecular NMR, vol. 71, no. 1, Springer Nature, 2018, pp.
53–67, doi:10.1007/s10858-018-0191-4.'
short: A. Krushelnitsky, D. Gauto, D.C. Rodriguez Camargo, P. Schanda, K. Saalwächter,
Journal of Biomolecular NMR 71 (2018) 53–67.
date_created: 2020-09-18T10:05:28Z
date_published: 2018-05-30T00:00:00Z
date_updated: 2021-01-12T08:19:17Z
day: '30'
doi: 10.1007/s10858-018-0191-4
extern: '1'
intvolume: ' 71'
issue: '1'
language:
- iso: eng
month: '05'
oa_version: Published Version
page: 53-67
publication: Journal of Biomolecular NMR
publication_identifier:
issn:
- 0925-2738
- 1573-5001
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: 'Microsecond motions probed by near-rotary-resonance R1ρ 15N MAS NMR experiments:
The model case of protein overall-rocking in crystals'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 71
year: '2018'
...
---
_id: '8442'
abstract:
- lang: eng
text: Membrane proteins perform a host of vital cellular functions. Deciphering
the molecular mechanisms whereby they fulfill these functions requires detailed
biophysical and structural investigations. Detergents have proven pivotal to extract
the protein from its native surroundings. Yet, they provide a milieu that departs
significantly from that of the biological membrane, to the extent that the structure,
the dynamics, and the interactions of membrane proteins in detergents may considerably
vary, as compared to the native environment. Understanding the impact of detergents
on membrane proteins is, therefore, crucial to assess the biological relevance
of results obtained in detergents. Here, we review the strengths and weaknesses
of alkyl phosphocholines (or foscholines), the most widely used detergent in solution-NMR
studies of membrane proteins. While this class of detergents is often successful
for membrane protein solubilization, a growing list of examples points to destabilizing
and denaturing properties, in particular for α-helical membrane proteins. Our
comprehensive analysis stresses the importance of stringent controls when working
with this class of detergents and when analyzing the structure and dynamics of
membrane proteins in alkyl phosphocholine detergents.
article_processing_charge: No
article_type: original
author:
- first_name: Christophe
full_name: Chipot, Christophe
last_name: Chipot
- first_name: François
full_name: Dehez, François
last_name: Dehez
- first_name: Jason R.
full_name: Schnell, Jason R.
last_name: Schnell
- first_name: Nicole
full_name: Zitzmann, Nicole
last_name: Zitzmann
- first_name: Eva
full_name: Pebay-Peyroula, Eva
last_name: Pebay-Peyroula
- first_name: Laurent J.
full_name: Catoire, Laurent J.
last_name: Catoire
- first_name: Bruno
full_name: Miroux, Bruno
last_name: Miroux
- first_name: Edmund R. S.
full_name: Kunji, Edmund R. S.
last_name: Kunji
- first_name: Gianluigi
full_name: Veglia, Gianluigi
last_name: Veglia
- first_name: Timothy A.
full_name: Cross, Timothy A.
last_name: Cross
- first_name: Paul
full_name: Schanda, Paul
id: 7B541462-FAF6-11E9-A490-E8DFE5697425
last_name: Schanda
orcid: 0000-0002-9350-7606
citation:
ama: 'Chipot C, Dehez F, Schnell JR, et al. Perturbations of native membrane protein
structure in alkyl phosphocholine detergents: A critical assessment of NMR and
biophysical studies. Chemical Reviews. 2018;118(7):3559-3607. doi:10.1021/acs.chemrev.7b00570'
apa: 'Chipot, C., Dehez, F., Schnell, J. R., Zitzmann, N., Pebay-Peyroula, E., Catoire,
L. J., … Schanda, P. (2018). Perturbations of native membrane protein structure
in alkyl phosphocholine detergents: A critical assessment of NMR and biophysical
studies. Chemical Reviews. American Chemical Society. https://doi.org/10.1021/acs.chemrev.7b00570'
chicago: 'Chipot, Christophe, François Dehez, Jason R. Schnell, Nicole Zitzmann,
Eva Pebay-Peyroula, Laurent J. Catoire, Bruno Miroux, et al. “Perturbations of
Native Membrane Protein Structure in Alkyl Phosphocholine Detergents: A Critical
Assessment of NMR and Biophysical Studies.” Chemical Reviews. American
Chemical Society, 2018. https://doi.org/10.1021/acs.chemrev.7b00570.'
ieee: 'C. Chipot et al., “Perturbations of native membrane protein structure
in alkyl phosphocholine detergents: A critical assessment of NMR and biophysical
studies,” Chemical Reviews, vol. 118, no. 7. American Chemical Society,
pp. 3559–3607, 2018.'
ista: 'Chipot C, Dehez F, Schnell JR, Zitzmann N, Pebay-Peyroula E, Catoire LJ,
Miroux B, Kunji ERS, Veglia G, Cross TA, Schanda P. 2018. Perturbations of native
membrane protein structure in alkyl phosphocholine detergents: A critical assessment
of NMR and biophysical studies. Chemical Reviews. 118(7), 3559–3607.'
mla: 'Chipot, Christophe, et al. “Perturbations of Native Membrane Protein Structure
in Alkyl Phosphocholine Detergents: A Critical Assessment of NMR and Biophysical
Studies.” Chemical Reviews, vol. 118, no. 7, American Chemical Society,
2018, pp. 3559–607, doi:10.1021/acs.chemrev.7b00570.'
short: C. Chipot, F. Dehez, J.R. Schnell, N. Zitzmann, E. Pebay-Peyroula, L.J. Catoire,
B. Miroux, E.R.S. Kunji, G. Veglia, T.A. Cross, P. Schanda, Chemical Reviews 118
(2018) 3559–3607.
date_created: 2020-09-18T10:05:35Z
date_published: 2018-02-28T00:00:00Z
date_updated: 2021-01-12T08:19:18Z
day: '28'
doi: 10.1021/acs.chemrev.7b00570
extern: '1'
intvolume: ' 118'
issue: '7'
keyword:
- General Chemistry
language:
- iso: eng
month: '02'
oa_version: None
page: 3559-3607
publication: Chemical Reviews
publication_identifier:
issn:
- 0009-2665
- 1520-6890
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
status: public
title: 'Perturbations of native membrane protein structure in alkyl phosphocholine
detergents: A critical assessment of NMR and biophysical studies'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 118
year: '2018'
...
---
_id: '8443'
abstract:
- lang: eng
text: Characterizing the structure of membrane proteins (MPs) generally requires
extraction from their native environment, most commonly with detergents. Yet,
the physicochemical properties of detergent micelles and lipid bilayers differ
markedly and could alter the structural organization of MPs, albeit without general
rules. Dodecylphosphocholine (DPC) is the most widely used detergent for MP structure
determination by NMR, but the physiological relevance of several prominent structures
has been questioned, though indirectly, by other biophysical techniques, e.g.,
functional/thermostability assay (TSA) and molecular dynamics (MD) simulations.
Here, we resolve unambiguously this controversy by probing the functional relevance
of three different mitochondrial carriers (MCs) in DPC at the atomic level, using
an exhaustive set of solution-NMR experiments, complemented by functional/TSA
and MD data. Our results provide atomic-level insight into the structure, substrate
interaction and dynamics of the detergent–membrane protein complexes and demonstrates
cogently that, while high-resolution NMR signals can be obtained for MCs in DPC,
they systematically correspond to nonfunctional states.
article_processing_charge: No
article_type: original
author:
- first_name: Vilius
full_name: Kurauskas, Vilius
last_name: Kurauskas
- first_name: Audrey
full_name: Hessel, Audrey
last_name: Hessel
- first_name: Peixiang
full_name: Ma, Peixiang
last_name: Ma
- first_name: Paola
full_name: Lunetti, Paola
last_name: Lunetti
- first_name: Katharina
full_name: Weinhäupl, Katharina
last_name: Weinhäupl
- first_name: Lionel
full_name: Imbert, Lionel
last_name: Imbert
- first_name: Bernhard
full_name: Brutscher, Bernhard
last_name: Brutscher
- first_name: Martin S.
full_name: King, Martin S.
last_name: King
- first_name: Rémy
full_name: Sounier, Rémy
last_name: Sounier
- first_name: Vincenza
full_name: Dolce, Vincenza
last_name: Dolce
- first_name: Edmund R. S.
full_name: Kunji, Edmund R. S.
last_name: Kunji
- first_name: Loredana
full_name: Capobianco, Loredana
last_name: Capobianco
- first_name: Christophe
full_name: Chipot, Christophe
last_name: Chipot
- first_name: François
full_name: Dehez, François
last_name: Dehez
- first_name: Beate
full_name: Bersch, Beate
last_name: Bersch
- first_name: Paul
full_name: Schanda, Paul
id: 7B541462-FAF6-11E9-A490-E8DFE5697425
last_name: Schanda
orcid: 0000-0002-9350-7606
citation:
ama: 'Kurauskas V, Hessel A, Ma P, et al. How detergent impacts membrane proteins:
Atomic-level views of mitochondrial carriers in dodecylphosphocholine. The
Journal of Physical Chemistry Letters. 2018;9(5):933-938. doi:10.1021/acs.jpclett.8b00269'
apa: 'Kurauskas, V., Hessel, A., Ma, P., Lunetti, P., Weinhäupl, K., Imbert, L.,
… Schanda, P. (2018). How detergent impacts membrane proteins: Atomic-level views
of mitochondrial carriers in dodecylphosphocholine. The Journal of Physical
Chemistry Letters. American Chemical Society. https://doi.org/10.1021/acs.jpclett.8b00269'
chicago: 'Kurauskas, Vilius, Audrey Hessel, Peixiang Ma, Paola Lunetti, Katharina
Weinhäupl, Lionel Imbert, Bernhard Brutscher, et al. “How Detergent Impacts Membrane
Proteins: Atomic-Level Views of Mitochondrial Carriers in Dodecylphosphocholine.”
The Journal of Physical Chemistry Letters. American Chemical Society, 2018.
https://doi.org/10.1021/acs.jpclett.8b00269.'
ieee: 'V. Kurauskas et al., “How detergent impacts membrane proteins: Atomic-level
views of mitochondrial carriers in dodecylphosphocholine,” The Journal of Physical
Chemistry Letters, vol. 9, no. 5. American Chemical Society, pp. 933–938,
2018.'
ista: 'Kurauskas V, Hessel A, Ma P, Lunetti P, Weinhäupl K, Imbert L, Brutscher
B, King MS, Sounier R, Dolce V, Kunji ERS, Capobianco L, Chipot C, Dehez F, Bersch
B, Schanda P. 2018. How detergent impacts membrane proteins: Atomic-level views
of mitochondrial carriers in dodecylphosphocholine. The Journal of Physical Chemistry
Letters. 9(5), 933–938.'
mla: 'Kurauskas, Vilius, et al. “How Detergent Impacts Membrane Proteins: Atomic-Level
Views of Mitochondrial Carriers in Dodecylphosphocholine.” The Journal of Physical
Chemistry Letters, vol. 9, no. 5, American Chemical Society, 2018, pp. 933–38,
doi:10.1021/acs.jpclett.8b00269.'
short: V. Kurauskas, A. Hessel, P. Ma, P. Lunetti, K. Weinhäupl, L. Imbert, B. Brutscher,
M.S. King, R. Sounier, V. Dolce, E.R.S. Kunji, L. Capobianco, C. Chipot, F. Dehez,
B. Bersch, P. Schanda, The Journal of Physical Chemistry Letters 9 (2018) 933–938.
date_created: 2020-09-18T10:05:45Z
date_published: 2018-02-03T00:00:00Z
date_updated: 2021-01-12T08:19:18Z
day: '03'
doi: 10.1021/acs.jpclett.8b00269
extern: '1'
intvolume: ' 9'
issue: '5'
keyword:
- General Materials Science
language:
- iso: eng
month: '02'
oa_version: None
page: 933-938
publication: The Journal of Physical Chemistry Letters
publication_identifier:
issn:
- 1948-7185
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
status: public
title: 'How detergent impacts membrane proteins: Atomic-level views of mitochondrial
carriers in dodecylphosphocholine'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9
year: '2018'
...
---
_id: '85'
abstract:
- lang: eng
text: Concurrent accesses to shared data structures must be synchronized to avoid
data races. Coarse-grained synchronization, which locks the entire data structure,
is easy to implement but does not scale. Fine-grained synchronization can scale
well, but can be hard to reason about. Hand-over-hand locking, in which operations
are pipelined as they traverse the data structure, combines fine-grained synchronization
with ease of use. However, the traditional implementation suffers from inherent
overheads. This paper introduces snapshot-based synchronization (SBS), a novel
hand-over-hand locking mechanism. SBS decouples the synchronization state from
the data, significantly improving cache utilization. Further, it relies on guarantees
provided by pipelining to minimize synchronization that requires cross-thread
communication. Snapshot-based synchronization thus scales much better than traditional
hand-over-hand locking, while maintaining the same ease of use.
acknowledgement: Trevor Brown was supported in part by the ISF (grants 2005/17 & 1749/14)
and by a NSERC post-doctoral fellowship.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Eran
full_name: Gilad, Eran
last_name: Gilad
- first_name: Trevor A
full_name: Brown, Trevor A
id: 3569F0A0-F248-11E8-B48F-1D18A9856A87
last_name: Brown
- first_name: Mark
full_name: Oskin, Mark
last_name: Oskin
- first_name: Yoav
full_name: Etsion, Yoav
last_name: Etsion
citation:
ama: 'Gilad E, Brown TA, Oskin M, Etsion Y. Snapshot based synchronization: A fast
replacement for Hand-over-Hand locking. In: Vol 11014. Springer; 2018:465-479.
doi:10.1007/978-3-319-96983-1_33'
apa: 'Gilad, E., Brown, T. A., Oskin, M., & Etsion, Y. (2018). Snapshot based
synchronization: A fast replacement for Hand-over-Hand locking (Vol. 11014, pp.
465–479). Presented at the Euro-Par: European Conference on Parallel Processing,
Turin, Italy: Springer. https://doi.org/10.1007/978-3-319-96983-1_33'
chicago: 'Gilad, Eran, Trevor A Brown, Mark Oskin, and Yoav Etsion. “Snapshot Based
Synchronization: A Fast Replacement for Hand-over-Hand Locking,” 11014:465–79.
Springer, 2018. https://doi.org/10.1007/978-3-319-96983-1_33.'
ieee: 'E. Gilad, T. A. Brown, M. Oskin, and Y. Etsion, “Snapshot based synchronization:
A fast replacement for Hand-over-Hand locking,” presented at the Euro-Par: European
Conference on Parallel Processing, Turin, Italy, 2018, vol. 11014, pp. 465–479.'
ista: 'Gilad E, Brown TA, Oskin M, Etsion Y. 2018. Snapshot based synchronization:
A fast replacement for Hand-over-Hand locking. Euro-Par: European Conference on
Parallel Processing, LNCS, vol. 11014, 465–479.'
mla: 'Gilad, Eran, et al. Snapshot Based Synchronization: A Fast Replacement
for Hand-over-Hand Locking. Vol. 11014, Springer, 2018, pp. 465–79, doi:10.1007/978-3-319-96983-1_33.'
short: E. Gilad, T.A. Brown, M. Oskin, Y. Etsion, in:, Springer, 2018, pp. 465–479.
conference:
end_date: 2018-08-31
location: Turin, Italy
name: 'Euro-Par: European Conference on Parallel Processing'
start_date: 2018-08-27
date_created: 2018-12-11T11:44:33Z
date_published: 2018-08-01T00:00:00Z
date_updated: 2023-09-18T09:32:36Z
day: '01'
ddc:
- '000'
department:
- _id: DaAl
doi: 10.1007/978-3-319-96983-1_33
external_id:
isi:
- '000851042300031'
file:
- access_level: open_access
checksum: 13a3f250be8878405e791b53c19722ad
content_type: application/pdf
creator: dernst
date_created: 2019-02-12T07:40:40Z
date_updated: 2020-07-14T12:48:14Z
file_id: '5954'
file_name: 2018_Brown.pdf
file_size: 665372
relation: main_file
file_date_updated: 2020-07-14T12:48:14Z
has_accepted_license: '1'
intvolume: ' 11014'
isi: 1
language:
- iso: eng
month: '08'
oa: 1
oa_version: Preprint
page: 465 - 479
project:
- _id: 26450934-B435-11E9-9278-68D0E5697425
name: NSERC Postdoctoral fellowship
publication_identifier:
issn:
- '03029743'
publication_status: published
publisher: Springer
publist_id: '7969'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Snapshot based synchronization: A fast replacement for Hand-over-Hand locking'
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 11014
year: '2018'
...
---
_id: '8547'
abstract:
- lang: eng
text: The cerebral cortex contains multiple hierarchically organized areas with
distinctive cytoarchitectonical patterns, but the cellular mechanisms underlying
the emergence of this diversity remain unclear. Here, we have quantitatively investigated
the neuronal output of individual progenitor cells in the ventricular zone of
the developing mouse neocortex using a combination of methods that together circumvent
the biases and limitations of individual approaches. We found that individual
cortical progenitor cells show a high degree of stochasticity and generate pyramidal
cell lineages that adopt a wide range of laminar configurations. Mathematical
modelling these lineage data suggests that a small number of progenitor cell populations,
each generating pyramidal cells following different stochastic developmental programs,
suffice to generate the heterogenous complement of pyramidal cell lineages that
collectively build the complex cytoarchitecture of the neocortex.
acknowledgement: We thank I. Andrew and S.E. Bae for excellent technical assistance,
F. Gage for plasmids, and K. Nave (Nex-Cre) for mouse colonies. We thank members
of the Marín and Rico laboratories for stimulating discussions and ideas. Our research
on this topic is supported by grants from the European Research Council (ERC-2017-AdG
787355 to O.M and ERC2016-CoG 725780 to S.H.) and Wellcome Trust (103714MA) to O.M.
L.L. was the recipient of an EMBO long-term postdoctoral fellowship, R.B. received
support from FWF Lise-Meitner program (M 2416) and F.K.W. was supported by an EMBO
postdoctoral fellowship and is currently a Marie Skłodowska-Curie Fellow from the
European Commission under the H2020 Programme.
article_processing_charge: No
author:
- first_name: Alfredo
full_name: Llorca, Alfredo
last_name: Llorca
- first_name: Gabriele
full_name: Ciceri, Gabriele
last_name: Ciceri
- first_name: Robert J
full_name: Beattie, Robert J
id: 2E26DF60-F248-11E8-B48F-1D18A9856A87
last_name: Beattie
orcid: 0000-0002-8483-8753
- first_name: Fong K.
full_name: Wong, Fong K.
last_name: Wong
- first_name: Giovanni
full_name: Diana, Giovanni
last_name: Diana
- first_name: Eleni
full_name: Serafeimidou, Eleni
last_name: Serafeimidou
- first_name: Marian
full_name: Fernández-Otero, Marian
last_name: Fernández-Otero
- first_name: Carmen
full_name: Streicher, Carmen
id: 36BCB99C-F248-11E8-B48F-1D18A9856A87
last_name: Streicher
- first_name: Sebastian J.
full_name: Arnold, Sebastian J.
last_name: Arnold
- first_name: Martin
full_name: Meyer, Martin
last_name: Meyer
- first_name: Simon
full_name: Hippenmeyer, Simon
id: 37B36620-F248-11E8-B48F-1D18A9856A87
last_name: Hippenmeyer
orcid: 0000-0003-2279-1061
- first_name: Miguel
full_name: Maravall, Miguel
last_name: Maravall
- first_name: Oscar
full_name: Marín, Oscar
last_name: Marín
citation:
ama: Llorca A, Ciceri G, Beattie RJ, et al. Heterogeneous progenitor cell behaviors
underlie the assembly of neocortical cytoarchitecture. bioRxiv. doi:10.1101/494088
apa: Llorca, A., Ciceri, G., Beattie, R. J., Wong, F. K., Diana, G., Serafeimidou,
E., … Marín, O. (n.d.). Heterogeneous progenitor cell behaviors underlie the assembly
of neocortical cytoarchitecture. bioRxiv. Cold Spring Harbor Laboratory.
https://doi.org/10.1101/494088
chicago: Llorca, Alfredo, Gabriele Ciceri, Robert J Beattie, Fong K. Wong, Giovanni
Diana, Eleni Serafeimidou, Marian Fernández-Otero, et al. “Heterogeneous Progenitor
Cell Behaviors Underlie the Assembly of Neocortical Cytoarchitecture.” BioRxiv.
Cold Spring Harbor Laboratory, n.d. https://doi.org/10.1101/494088.
ieee: A. Llorca et al., “Heterogeneous progenitor cell behaviors underlie
the assembly of neocortical cytoarchitecture,” bioRxiv. Cold Spring Harbor
Laboratory.
ista: Llorca A, Ciceri G, Beattie RJ, Wong FK, Diana G, Serafeimidou E, Fernández-Otero
M, Streicher C, Arnold SJ, Meyer M, Hippenmeyer S, Maravall M, Marín O. Heterogeneous
progenitor cell behaviors underlie the assembly of neocortical cytoarchitecture.
bioRxiv, 10.1101/494088.
mla: Llorca, Alfredo, et al. “Heterogeneous Progenitor Cell Behaviors Underlie the
Assembly of Neocortical Cytoarchitecture.” BioRxiv, Cold Spring Harbor
Laboratory, doi:10.1101/494088.
short: A. Llorca, G. Ciceri, R.J. Beattie, F.K. Wong, G. Diana, E. Serafeimidou,
M. Fernández-Otero, C. Streicher, S.J. Arnold, M. Meyer, S. Hippenmeyer, M. Maravall,
O. Marín, BioRxiv (n.d.).
date_created: 2020-09-21T12:01:50Z
date_published: 2018-12-13T00:00:00Z
date_updated: 2021-01-12T08:20:00Z
day: '13'
department:
- _id: SiHi
doi: 10.1101/494088
ec_funded: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1101/494088
month: '12'
oa: 1
oa_version: Preprint
project:
- _id: 260018B0-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '725780'
name: Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development
- _id: 264E56E2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: M02416
name: Molecular Mechanisms Regulating Gliogenesis in the Cerebral Cortex
publication: bioRxiv
publication_status: submitted
publisher: Cold Spring Harbor Laboratory
status: public
title: Heterogeneous progenitor cell behaviors underlie the assembly of neocortical
cytoarchitecture
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2018'
...
---
_id: '86'
abstract:
- lang: eng
text: Responsiveness—the requirement that every request to a system be eventually
handled—is one of the fundamental liveness properties of a reactive system. Average
response time is a quantitative measure for the responsiveness requirement used
commonly in performance evaluation. We show how average response time can be computed
on state-transition graphs, on Markov chains, and on game graphs. In all three
cases, we give polynomial-time algorithms.
acknowledgement: 'This research was supported in part by the Austrian Science Fund
(FWF) under grants S11402-N23, S11407-N23 (RiSE/SHiNE) and Z211-N23 (Wittgenstein
Award), ERC Start grant (279307: Graph Games), Vienna Science and Technology Fund
(WWTF) through project ICT15-003 and by the National Science Centre (NCN), Poland
under grant 2014/15/D/ST6/04543.'
alternative_title:
- LNCS
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Jan
full_name: Otop, Jan
id: 2FC5DA74-F248-11E8-B48F-1D18A9856A87
last_name: Otop
citation:
ama: 'Chatterjee K, Henzinger TA, Otop J. Computing average response time. In: Lohstroh
M, Derler P, Sirjani M, eds. Principles of Modeling. Vol 10760. Springer;
2018:143-161. doi:10.1007/978-3-319-95246-8_9'
apa: Chatterjee, K., Henzinger, T. A., & Otop, J. (2018). Computing average
response time. In M. Lohstroh, P. Derler, & M. Sirjani (Eds.), Principles
of Modeling (Vol. 10760, pp. 143–161). Springer. https://doi.org/10.1007/978-3-319-95246-8_9
chicago: Chatterjee, Krishnendu, Thomas A Henzinger, and Jan Otop. “Computing Average
Response Time.” In Principles of Modeling, edited by Marten Lohstroh, Patricia
Derler, and Marjan Sirjani, 10760:143–61. Springer, 2018. https://doi.org/10.1007/978-3-319-95246-8_9.
ieee: K. Chatterjee, T. A. Henzinger, and J. Otop, “Computing average response time,”
in Principles of Modeling, vol. 10760, M. Lohstroh, P. Derler, and M. Sirjani,
Eds. Springer, 2018, pp. 143–161.
ista: 'Chatterjee K, Henzinger TA, Otop J. 2018.Computing average response time.
In: Principles of Modeling. LNCS, vol. 10760, 143–161.'
mla: Chatterjee, Krishnendu, et al. “Computing Average Response Time.” Principles
of Modeling, edited by Marten Lohstroh et al., vol. 10760, Springer, 2018,
pp. 143–61, doi:10.1007/978-3-319-95246-8_9.
short: K. Chatterjee, T.A. Henzinger, J. Otop, in:, M. Lohstroh, P. Derler, M. Sirjani
(Eds.), Principles of Modeling, Springer, 2018, pp. 143–161.
date_created: 2018-12-11T11:44:33Z
date_published: 2018-07-20T00:00:00Z
date_updated: 2021-01-12T08:20:14Z
day: '20'
ddc:
- '000'
department:
- _id: KrCh
- _id: ToHe
doi: 10.1007/978-3-319-95246-8_9
ec_funded: 1
editor:
- first_name: Marten
full_name: Lohstroh, Marten
last_name: Lohstroh
- first_name: Patricia
full_name: Derler, Patricia
last_name: Derler
- first_name: Marjan
full_name: Sirjani, Marjan
last_name: Sirjani
file:
- access_level: open_access
checksum: 9995c6ce6957333baf616fc4f20be597
content_type: application/pdf
creator: dernst
date_created: 2019-11-19T08:22:18Z
date_updated: 2020-07-14T12:48:14Z
file_id: '7053'
file_name: 2018_PrinciplesModeling_Chatterjee.pdf
file_size: 516307
relation: main_file
file_date_updated: 2020-07-14T12:48:14Z
has_accepted_license: '1'
intvolume: ' 10760'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Submitted Version
page: 143 - 161
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11407
name: Game Theory
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z211
name: The Wittgenstein Prize
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 25892FC0-B435-11E9-9278-68D0E5697425
grant_number: ICT15-003
name: Efficient Algorithms for Computer Aided Verification
publication: Principles of Modeling
publication_status: published
publisher: Springer
publist_id: '7968'
quality_controlled: '1'
scopus_import: 1
status: public
title: Computing average response time
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 10760
year: '2018'
...
---
_id: '8618'
abstract:
- lang: eng
text: The reversibly switchable fluorescent proteins (RSFPs) commonly used for RESOLFT
nanoscopy have been developed from fluorescent proteins of the GFP superfamily.
These proteins are bright, but exhibit several drawbacks such as relatively large
size, oxygen-dependence, sensitivity to low pH, and limited switching speed. Therefore,
RSFPs from other origins with improved properties need to be explored. Here, we
report the development of two RSFPs based on the LOV domain of the photoreceptor
protein YtvA from Bacillus subtilis. LOV domains obtain their fluorescence by
association with the abundant cellular cofactor flavin mononucleotide (FMN). Under
illumination with blue and ultraviolet light, they undergo a photocycle, making
these proteins inherently photoswitchable. Our first improved variant, rsLOV1,
can be used for RESOLFT imaging, whereas rsLOV2 proved useful for STED nanoscopy
of living cells with a resolution of down to 50 nm. In addition to their smaller
size compared to GFP-related proteins (17 kDa instead of 27 kDa) and their usability
at low pH, rsLOV1 and rsLOV2 exhibit faster switching kinetics, switching on and
off 3 times faster than rsEGFP2, the fastest-switching RSFP reported to date.
Therefore, LOV-domain-based RSFPs have potential for applications where the switching
speed of GFP-based proteins is limiting.
article_number: '2724'
article_processing_charge: No
article_type: original
author:
- first_name: Carola
full_name: Gregor, Carola
last_name: Gregor
- first_name: Sven C.
full_name: Sidenstein, Sven C.
last_name: Sidenstein
- first_name: Martin
full_name: Andresen, Martin
last_name: Andresen
- first_name: Steffen J.
full_name: Sahl, Steffen J.
last_name: Sahl
- first_name: Johann G
full_name: Danzl, Johann G
id: 42EFD3B6-F248-11E8-B48F-1D18A9856A87
last_name: Danzl
orcid: 0000-0001-8559-3973
- first_name: Stefan W.
full_name: Hell, Stefan W.
last_name: Hell
citation:
ama: Gregor C, Sidenstein SC, Andresen M, Sahl SJ, Danzl JG, Hell SW. Novel reversibly
switchable fluorescent proteins for RESOLFT and STED nanoscopy engineered from
the bacterial photoreceptor YtvA. Scientific Reports. 2018;8. doi:10.1038/s41598-018-19947-1
apa: Gregor, C., Sidenstein, S. C., Andresen, M., Sahl, S. J., Danzl, J. G., &
Hell, S. W. (2018). Novel reversibly switchable fluorescent proteins for RESOLFT
and STED nanoscopy engineered from the bacterial photoreceptor YtvA. Scientific
Reports. Springer Nature. https://doi.org/10.1038/s41598-018-19947-1
chicago: Gregor, Carola, Sven C. Sidenstein, Martin Andresen, Steffen J. Sahl, Johann
G Danzl, and Stefan W. Hell. “Novel Reversibly Switchable Fluorescent Proteins
for RESOLFT and STED Nanoscopy Engineered from the Bacterial Photoreceptor YtvA.”
Scientific Reports. Springer Nature, 2018. https://doi.org/10.1038/s41598-018-19947-1.
ieee: C. Gregor, S. C. Sidenstein, M. Andresen, S. J. Sahl, J. G. Danzl, and S.
W. Hell, “Novel reversibly switchable fluorescent proteins for RESOLFT and STED
nanoscopy engineered from the bacterial photoreceptor YtvA,” Scientific Reports,
vol. 8. Springer Nature, 2018.
ista: Gregor C, Sidenstein SC, Andresen M, Sahl SJ, Danzl JG, Hell SW. 2018. Novel
reversibly switchable fluorescent proteins for RESOLFT and STED nanoscopy engineered
from the bacterial photoreceptor YtvA. Scientific Reports. 8, 2724.
mla: Gregor, Carola, et al. “Novel Reversibly Switchable Fluorescent Proteins for
RESOLFT and STED Nanoscopy Engineered from the Bacterial Photoreceptor YtvA.”
Scientific Reports, vol. 8, 2724, Springer Nature, 2018, doi:10.1038/s41598-018-19947-1.
short: C. Gregor, S.C. Sidenstein, M. Andresen, S.J. Sahl, J.G. Danzl, S.W. Hell,
Scientific Reports 8 (2018).
date_created: 2020-10-06T16:33:37Z
date_published: 2018-02-09T00:00:00Z
date_updated: 2023-09-19T15:04:49Z
day: '09'
ddc:
- '570'
department:
- _id: JoDa
doi: 10.1038/s41598-018-19947-1
external_id:
isi:
- '000424630400037'
pmid:
- '29426833'
file:
- access_level: open_access
checksum: e642080fcbde9584c63544f587c74f03
content_type: application/pdf
creator: dernst
date_created: 2020-10-06T16:35:16Z
date_updated: 2020-10-06T16:35:16Z
file_id: '8619'
file_name: 2018_ScientificReports_Gregor.pdf
file_size: 2818077
relation: main_file
success: 1
file_date_updated: 2020-10-06T16:35:16Z
has_accepted_license: '1'
intvolume: ' 8'
isi: 1
keyword:
- Multidisciplinary
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
pmid: 1
publication: Scientific Reports
publication_identifier:
issn:
- 2045-2322
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Novel reversibly switchable fluorescent proteins for RESOLFT and STED nanoscopy
engineered from the bacterial photoreceptor YtvA
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 8
year: '2018'
...
---
_id: '87'
abstract:
- lang: eng
text: Using the geodesic distance on the n-dimensional sphere, we study the expected
radius function of the Delaunay mosaic of a random set of points. Specifically,
we consider the partition of the mosaic into intervals of the radius function
and determine the expected number of intervals whose radii are less than or equal
to a given threshold. We find that the expectations are essentially the same as
for the Poisson–Delaunay mosaic in n-dimensional Euclidean space. Assuming the
points are not contained in a hemisphere, the Delaunay mosaic is isomorphic to
the boundary complex of the convex hull in Rn+1, so we also get the expected number
of faces of a random inscribed polytope. As proved in Antonelli et al. [Adv. in
Appl. Probab. 9–12 (1977–1980)], an orthant section of the n-sphere is isometric
to the standard n-simplex equipped with the Fisher information metric. It follows
that the latter space has similar stochastic properties as the n-dimensional Euclidean
space. Our results are therefore relevant in information geometry and in population
genetics.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Anton
full_name: Nikitenko, Anton
id: 3E4FF1BA-F248-11E8-B48F-1D18A9856A87
last_name: Nikitenko
orcid: 0000-0002-0659-3201
citation:
ama: Edelsbrunner H, Nikitenko A. Random inscribed polytopes have similar radius
functions as Poisson-Delaunay mosaics. Annals of Applied Probability. 2018;28(5):3215-3238.
doi:10.1214/18-AAP1389
apa: Edelsbrunner, H., & Nikitenko, A. (2018). Random inscribed polytopes have
similar radius functions as Poisson-Delaunay mosaics. Annals of Applied Probability.
Institute of Mathematical Statistics. https://doi.org/10.1214/18-AAP1389
chicago: Edelsbrunner, Herbert, and Anton Nikitenko. “Random Inscribed Polytopes
Have Similar Radius Functions as Poisson-Delaunay Mosaics.” Annals of Applied
Probability. Institute of Mathematical Statistics, 2018. https://doi.org/10.1214/18-AAP1389.
ieee: H. Edelsbrunner and A. Nikitenko, “Random inscribed polytopes have similar
radius functions as Poisson-Delaunay mosaics,” Annals of Applied Probability,
vol. 28, no. 5. Institute of Mathematical Statistics, pp. 3215–3238, 2018.
ista: Edelsbrunner H, Nikitenko A. 2018. Random inscribed polytopes have similar
radius functions as Poisson-Delaunay mosaics. Annals of Applied Probability. 28(5),
3215–3238.
mla: Edelsbrunner, Herbert, and Anton Nikitenko. “Random Inscribed Polytopes Have
Similar Radius Functions as Poisson-Delaunay Mosaics.” Annals of Applied Probability,
vol. 28, no. 5, Institute of Mathematical Statistics, 2018, pp. 3215–38, doi:10.1214/18-AAP1389.
short: H. Edelsbrunner, A. Nikitenko, Annals of Applied Probability 28 (2018) 3215–3238.
date_created: 2018-12-11T11:44:33Z
date_published: 2018-10-01T00:00:00Z
date_updated: 2023-09-15T12:10:35Z
day: '01'
department:
- _id: HeEd
doi: 10.1214/18-AAP1389
external_id:
arxiv:
- '1705.02870'
isi:
- '000442893500018'
intvolume: ' 28'
isi: 1
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1705.02870
month: '10'
oa: 1
oa_version: Preprint
page: 3215 - 3238
project:
- _id: 2561EBF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: I02979-N35
name: Persistence and stability of geometric complexes
publication: Annals of Applied Probability
publication_status: published
publisher: Institute of Mathematical Statistics
publist_id: '7967'
quality_controlled: '1'
related_material:
record:
- id: '6287'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Random inscribed polytopes have similar radius functions as Poisson-Delaunay
mosaics
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 28
year: '2018'
...
---
_id: '9'
abstract:
- lang: eng
text: 'Immune cells migrating to the sites of infection navigate through diverse
tissue architectures and switch their migratory mechanisms upon demand. However,
little is known about systemic regulators that could allow the acquisition of
these mechanisms. We performed a genetic screen in Drosophila melanogaster to
identify regulators of germband invasion by embryonic macrophages into the confined
space between the ectoderm and mesoderm. We have found that bZIP circadian transcription
factors (TFs) Kayak (dFos) and Vrille (dNFIL3) have opposite effects on macrophage
germband infiltration: Kayak facilitated and Vrille inhibited it. These TFs are
enriched in the macrophages during migration and genetically interact to control
it. Kayak sets a less coordinated mode of migration of the macrophage group and
increases the probability and length of Levy walks. Intriguingly, the motility
of kayak mutant macrophages was also strongly affected during initial germband
invasion but not along another less confined route. Inhibiting Rho1 signaling
within the tail ectoderm partially rescued the Kayak mutant phenotype, strongly
suggesting that migrating macrophages have to overcome a barrier imposed by the
stiffness of the ectoderm. Also, Kayak appeared to be important for the maintenance
of the round cell shape and the rear edge translocation of the macrophages invading
the germband. Complementary to this, the cortical actin cytoskeleton of Kayak-
deficient macrophages was strongly affected. RNA sequencing revealed the filamin
Cheerio and tetraspanin TM4SF to be downstream of Kayak. Chromatin immunoprecipitation
and immunostaining revealed that the formin Diaphanous is another downstream target
of Kayak. Immunostaining revealed that the formin Diaphanous is another downstream
target of Kayak. Indeed, Cheerio, TM4SF and Diaphanous are required within macrophages
for germband invasion, and expression of constitutively active Diaphanous in macrophages
was able to rescue the kayak mutant phenotype. Moreover, Cher and Diaphanous are
also reduced in the macrophages overexpressing Vrille. We hypothesize that Kayak,
through its targets, increases actin polymerization and cortical tension in macrophages
and thus allows extra force generation necessary for macrophage dissemination
and migration through confined stiff tissues, while Vrille counterbalances it.'
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Vera
full_name: Belyaeva, Vera
id: 47F080FE-F248-11E8-B48F-1D18A9856A87
last_name: Belyaeva
citation:
ama: Belyaeva V. Transcriptional regulation of macrophage migration in the Drosophila
melanogaster embryo . 2018. doi:10.15479/AT:ISTA:th1064
apa: Belyaeva, V. (2018). Transcriptional regulation of macrophage migration
in the Drosophila melanogaster embryo . Institute of Science and Technology
Austria. https://doi.org/10.15479/AT:ISTA:th1064
chicago: Belyaeva, Vera. “Transcriptional Regulation of Macrophage Migration in
the Drosophila Melanogaster Embryo .” Institute of Science and Technology Austria,
2018. https://doi.org/10.15479/AT:ISTA:th1064.
ieee: V. Belyaeva, “Transcriptional regulation of macrophage migration in the Drosophila
melanogaster embryo ,” Institute of Science and Technology Austria, 2018.
ista: Belyaeva V. 2018. Transcriptional regulation of macrophage migration in the
Drosophila melanogaster embryo . Institute of Science and Technology Austria.
mla: Belyaeva, Vera. Transcriptional Regulation of Macrophage Migration in the
Drosophila Melanogaster Embryo . Institute of Science and Technology Austria,
2018, doi:10.15479/AT:ISTA:th1064.
short: V. Belyaeva, Transcriptional Regulation of Macrophage Migration in the Drosophila
Melanogaster Embryo , Institute of Science and Technology Austria, 2018.
date_created: 2018-12-11T11:44:08Z
date_published: 2018-07-01T00:00:00Z
date_updated: 2023-09-07T12:43:10Z
day: '01'
ddc:
- '570'
degree_awarded: PhD
department:
- _id: DaSi
doi: 10.15479/AT:ISTA:th1064
file:
- access_level: closed
checksum: d27b2465cb70d0c9678a0381b9b6ced1
content_type: application/vnd.openxmlformats-officedocument.wordprocessingml.document
creator: dernst
date_created: 2019-04-08T14:13:12Z
date_updated: 2020-07-14T12:48:14Z
embargo_to: open_access
file_id: '6243'
file_name: 2018_Thesis_Belyaeva_source.docx
file_size: 102737483
relation: source_file
- access_level: open_access
checksum: a2939b61bde2de7b8ced77bbae0eaaed
content_type: application/pdf
creator: dernst
date_created: 2019-04-08T14:14:08Z
date_updated: 2021-02-11T11:17:16Z
embargo: 2019-11-19
file_id: '6244'
file_name: 2018_Thesis_Belyaeva.pdf
file_size: 88077843
relation: main_file
file_date_updated: 2021-02-11T11:17:16Z
has_accepted_license: '1'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: '96'
publication_identifier:
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
publist_id: '8047'
pubrep_id: '1064'
status: public
supervisor:
- first_name: Daria E
full_name: Siekhaus, Daria E
id: 3D224B9E-F248-11E8-B48F-1D18A9856A87
last_name: Siekhaus
orcid: 0000-0001-8323-8353
title: 'Transcriptional regulation of macrophage migration in the Drosophila melanogaster
embryo '
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2018'
...
---
_id: '9053'
abstract:
- lang: eng
text: The development of strategies to assemble microscopic machines from dissipative
building blocks are essential on the route to novel active materials. We recently
demonstrated the hierarchical self-assembly of phoretic microswimmers into self-spinning
microgears and their synchronization by diffusiophoretic interactions [Aubret
et al., Nat. Phys., 2018]. In this paper, we adopt a pedagogical approach and
expose our strategy to control self-assembly and build machines using phoretic
phenomena. We notably introduce Highly Inclined Laminated Optical sheets microscopy
(HILO) to image and characterize anisotropic and dynamic diffusiophoretic interactions,
which cannot be performed by conventional fluorescence microscopy. The dynamics
of a (haematite) photocatalytic material immersed in (hydrogen peroxide) fuel
under various illumination patterns is first described and quantitatively rationalized
by a model of diffusiophoresis, the migration of a colloidal particle in a concentration
gradient. It is further exploited to design phototactic microswimmers that direct
towards the high intensity of light, as a result of the reorientation of the haematite
in a light gradient. We finally show the assembly of self-spinning microgears
from colloidal microswimmers and carefully characterize the interactions using
HILO techniques. The results are compared with analytical and numerical predictions
and agree quantitatively, stressing the important role played by concentration
gradients induced by chemical activity to control and design interactions. Because
the approach described hereby is generic, this works paves the way for the rational
design of machines by controlling phoretic phenomena.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Antoine
full_name: Aubret, Antoine
last_name: Aubret
- first_name: Jérémie A
full_name: Palacci, Jérémie A
id: 8fb92548-2b22-11eb-b7c1-a3f0d08d7c7d
last_name: Palacci
orcid: 0000-0002-7253-9465
citation:
ama: Aubret A, Palacci JA. Diffusiophoretic design of self-spinning microgears from
colloidal microswimmers. Soft Matter. 2018;14(47):9577-9588. doi:10.1039/c8sm01760c
apa: Aubret, A., & Palacci, J. A. (2018). Diffusiophoretic design of self-spinning
microgears from colloidal microswimmers. Soft Matter. Royal Society of
Chemistry . https://doi.org/10.1039/c8sm01760c
chicago: Aubret, Antoine, and Jérémie A Palacci. “Diffusiophoretic Design of Self-Spinning
Microgears from Colloidal Microswimmers.” Soft Matter. Royal Society of
Chemistry , 2018. https://doi.org/10.1039/c8sm01760c.
ieee: A. Aubret and J. A. Palacci, “Diffusiophoretic design of self-spinning microgears
from colloidal microswimmers,” Soft Matter, vol. 14, no. 47. Royal Society
of Chemistry , pp. 9577–9588, 2018.
ista: Aubret A, Palacci JA. 2018. Diffusiophoretic design of self-spinning microgears
from colloidal microswimmers. Soft Matter. 14(47), 9577–9588.
mla: Aubret, Antoine, and Jérémie A. Palacci. “Diffusiophoretic Design of Self-Spinning
Microgears from Colloidal Microswimmers.” Soft Matter, vol. 14, no. 47,
Royal Society of Chemistry , 2018, pp. 9577–88, doi:10.1039/c8sm01760c.
short: A. Aubret, J.A. Palacci, Soft Matter 14 (2018) 9577–9588.
date_created: 2021-02-01T13:44:41Z
date_published: 2018-12-21T00:00:00Z
date_updated: 2023-02-23T13:47:43Z
day: '21'
doi: 10.1039/c8sm01760c
extern: '1'
external_id:
arxiv:
- '1909.11121'
pmid:
- '30456407'
intvolume: ' 14'
issue: '47'
keyword:
- General Chemistry
- Condensed Matter Physics
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1909.11121
month: '12'
oa: 1
oa_version: Preprint
page: 9577-9588
pmid: 1
publication: Soft Matter
publication_identifier:
eissn:
- 1744-6848
issn:
- 1744-683X
publication_status: published
publisher: 'Royal Society of Chemistry '
quality_controlled: '1'
scopus_import: '1'
status: public
title: Diffusiophoretic design of self-spinning microgears from colloidal microswimmers
type: journal_article
user_id: D865714E-FA4E-11E9-B85B-F5C5E5697425
volume: 14
year: '2018'
...
---
_id: '9062'
abstract:
- lang: eng
text: 'Self-assembly is the autonomous organization of components into patterns
or structures: an essential ingredient of biology and a desired route to complex
organization1. At equilibrium, the structure is encoded through specific interactions2,3,4,5,6,7,8,
at an unfavourable entropic cost for the system. An alternative approach, widely
used by nature, uses energy input to bypass the entropy bottleneck and develop
features otherwise impossible at equilibrium9. Dissipative building blocks that
inject energy locally were made available by recent advances in colloidal science10,11
but have not been used to control self-assembly. Here we show the targeted formation
of self-powered microgears from active particles and their autonomous synchronization
into dynamical superstructures. We use a photoactive component that consumes fuel,
haematite, to devise phototactic microswimmers that form self-spinning microgears
following spatiotemporal light patterns. The gears are coupled via their chemical
clouds by diffusiophoresis12 and constitute the elementary bricks of synchronized
superstructures, which autonomously regulate their dynamics. The results are quantitatively
rationalized on the basis of a stochastic description of diffusio-phoretic oscillators
dynamically coupled by chemical gradients. Our findings harness non-equilibrium
phoretic phenomena to program interactions and direct self-assembly with fidelity
and specificity. It lays the groundwork for the autonomous construction of dynamical
architectures and functional micro-machinery.'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Antoine
full_name: Aubret, Antoine
last_name: Aubret
- first_name: Mena
full_name: Youssef, Mena
last_name: Youssef
- first_name: Stefano
full_name: Sacanna, Stefano
last_name: Sacanna
- first_name: Jérémie A
full_name: Palacci, Jérémie A
id: 8fb92548-2b22-11eb-b7c1-a3f0d08d7c7d
last_name: Palacci
orcid: 0000-0002-7253-9465
citation:
ama: Aubret A, Youssef M, Sacanna S, Palacci JA. Targeted assembly and synchronization
of self-spinning microgears. Nature Physics. 2018;14(11):1114-1118. doi:10.1038/s41567-018-0227-4
apa: Aubret, A., Youssef, M., Sacanna, S., & Palacci, J. A. (2018). Targeted
assembly and synchronization of self-spinning microgears. Nature Physics.
Springer Nature. https://doi.org/10.1038/s41567-018-0227-4
chicago: Aubret, Antoine, Mena Youssef, Stefano Sacanna, and Jérémie A Palacci.
“Targeted Assembly and Synchronization of Self-Spinning Microgears.” Nature
Physics. Springer Nature, 2018. https://doi.org/10.1038/s41567-018-0227-4.
ieee: A. Aubret, M. Youssef, S. Sacanna, and J. A. Palacci, “Targeted assembly and
synchronization of self-spinning microgears,” Nature Physics, vol. 14,
no. 11. Springer Nature, pp. 1114–1118, 2018.
ista: Aubret A, Youssef M, Sacanna S, Palacci JA. 2018. Targeted assembly and synchronization
of self-spinning microgears. Nature Physics. 14(11), 1114–1118.
mla: Aubret, Antoine, et al. “Targeted Assembly and Synchronization of Self-Spinning
Microgears.” Nature Physics, vol. 14, no. 11, Springer Nature, 2018, pp.
1114–18, doi:10.1038/s41567-018-0227-4.
short: A. Aubret, M. Youssef, S. Sacanna, J.A. Palacci, Nature Physics 14 (2018)
1114–1118.
date_created: 2021-02-02T13:52:49Z
date_published: 2018-11-01T00:00:00Z
date_updated: 2023-02-23T13:48:02Z
day: '01'
doi: 10.1038/s41567-018-0227-4
extern: '1'
external_id:
arxiv:
- '1810.01033'
intvolume: ' 14'
issue: '11'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1810.01033
month: '11'
oa: 1
oa_version: Preprint
page: 1114-1118
publication: Nature Physics
publication_identifier:
eissn:
- 1745-2481
issn:
- 1745-2473
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Targeted assembly and synchronization of self-spinning microgears
type: journal_article
user_id: D865714E-FA4E-11E9-B85B-F5C5E5697425
volume: 14
year: '2018'
...
---
_id: '9066'
abstract:
- lang: eng
text: The novel electronic state of the canted antiferromagnetic (AFM) insulator,
strontium iridate (Sr2IrO4) has been well described by the spin-orbit-entangled
isospin Jeff = 1/2, but the role of isospin in transport phenomena remains poorly
understood. In this study, antiferromagnet-based spintronic functionality is demonstrated
by combining unique characteristics of the isospin state in Sr2IrO4. Based on
magnetic and transport measurements, large and highly anisotropic magnetoresistance
(AMR) is obtained by manipulating the antiferromagnetic isospin domains. First-principles
calculations suggest that electrons whose isospin directions are strongly coupled
to in-plane net magnetic moment encounter the isospin mismatch when moving across
antiferromagnetic domain boundaries, which generates a high resistance state.
By rotating a magnetic field that aligns in-plane net moments and removes domain
boundaries, the macroscopically-ordered isospins govern dynamic transport through
the system, which leads to the extremely angle-sensitive AMR. As with this work
that establishes a link between isospins and magnetotransport in strongly spin-orbit-coupled
AFM Sr2IrO4, the peculiar AMR effect provides a beneficial foundation for fundamental
and applied research on AFM spintronics.
article_number: '1805564'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Nara
full_name: Lee, Nara
last_name: Lee
- first_name: Eunjung
full_name: Ko, Eunjung
last_name: Ko
- first_name: Hwan Young
full_name: Choi, Hwan Young
last_name: Choi
- first_name: Yun Jeong
full_name: Hong, Yun Jeong
last_name: Hong
- first_name: Muhammad
full_name: Nauman, Muhammad
id: 32c21954-2022-11eb-9d5f-af9f93c24e71
last_name: Nauman
orcid: 0000-0002-2111-4846
- first_name: Woun
full_name: Kang, Woun
last_name: Kang
- first_name: Hyoung Joon
full_name: Choi, Hyoung Joon
last_name: Choi
- first_name: Young Jai
full_name: Choi, Young Jai
last_name: Choi
- first_name: Younjung
full_name: Jo, Younjung
last_name: Jo
citation:
ama: Lee N, Ko E, Choi HY, et al. Antiferromagnet‐based spintronic functionality
by controlling isospin domains in a layered perovskite iridate. Advanced Materials.
2018;30(52). doi:10.1002/adma.201805564
apa: Lee, N., Ko, E., Choi, H. Y., Hong, Y. J., Nauman, M., Kang, W., … Jo, Y. (2018).
Antiferromagnet‐based spintronic functionality by controlling isospin domains
in a layered perovskite iridate. Advanced Materials. Wiley. https://doi.org/10.1002/adma.201805564
chicago: Lee, Nara, Eunjung Ko, Hwan Young Choi, Yun Jeong Hong, Muhammad Nauman,
Woun Kang, Hyoung Joon Choi, Young Jai Choi, and Younjung Jo. “Antiferromagnet‐based
Spintronic Functionality by Controlling Isospin Domains in a Layered Perovskite
Iridate.” Advanced Materials. Wiley, 2018. https://doi.org/10.1002/adma.201805564.
ieee: N. Lee et al., “Antiferromagnet‐based spintronic functionality by controlling
isospin domains in a layered perovskite iridate,” Advanced Materials, vol.
30, no. 52. Wiley, 2018.
ista: Lee N, Ko E, Choi HY, Hong YJ, Nauman M, Kang W, Choi HJ, Choi YJ, Jo Y. 2018.
Antiferromagnet‐based spintronic functionality by controlling isospin domains
in a layered perovskite iridate. Advanced Materials. 30(52), 1805564.
mla: Lee, Nara, et al. “Antiferromagnet‐based Spintronic Functionality by Controlling
Isospin Domains in a Layered Perovskite Iridate.” Advanced Materials, vol.
30, no. 52, 1805564, Wiley, 2018, doi:10.1002/adma.201805564.
short: N. Lee, E. Ko, H.Y. Choi, Y.J. Hong, M. Nauman, W. Kang, H.J. Choi, Y.J.
Choi, Y. Jo, Advanced Materials 30 (2018).
date_created: 2021-02-02T15:50:58Z
date_published: 2018-10-29T00:00:00Z
date_updated: 2021-02-03T13:58:39Z
day: '29'
doi: 10.1002/adma.201805564
extern: '1'
external_id:
arxiv:
- '1811.04562'
intvolume: ' 30'
issue: '52'
keyword:
- Mechanical Engineering
- General Materials Science
- Mechanics of Materials
language:
- iso: eng
month: '10'
oa_version: Preprint
publication: Advanced Materials
publication_identifier:
issn:
- 0935-9648
- 1521-4095
publication_status: published
publisher: Wiley
quality_controlled: '1'
status: public
title: Antiferromagnet‐based spintronic functionality by controlling isospin domains
in a layered perovskite iridate
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 30
year: '2018'
...
---
_id: '9068'
abstract:
- lang: eng
text: We report the temperature-dependent resistivity ρ(T) of chalcogenide NiS2-xSex
(x = 0.1) using hydrostatic pressure as a control parameter in the temperature
range of 4–300 K. The insulating behavior of ρ(T) survives at low temperatures
in the pressure regime below 7.5 kbar, whereas a clear insulator-to-metallic transition
is observed above 7.5 kbar. Two types of magnetic transitions, from the paramagnetic
(PM) to the antiferromagnetic (AFM) state and from the AFM state to the weak ferromagnetic
(WF) state, were evaluated and confirmed by magnetization measurement. According
to the temperature–pressure phase diagram, the WF phase survives up to 7.5 kbar,
and the transition temperature of the WF transition decreases as the pressure
increases, whereas the metal–insulator transition temperature increases up to
9.4 kbar. We analyzed the metallic behavior and proposed Fermi-liquid behavior
of NiS1.9Se0.1.
article_processing_charge: No
article_type: original
author:
- first_name: Tayyaba
full_name: Hussain, Tayyaba
last_name: Hussain
- first_name: Myeong-jun
full_name: Oh, Myeong-jun
last_name: Oh
- first_name: Muhammad
full_name: Nauman, Muhammad
id: 32c21954-2022-11eb-9d5f-af9f93c24e71
last_name: Nauman
orcid: 0000-0002-2111-4846
- first_name: Younjung
full_name: Jo, Younjung
last_name: Jo
- first_name: Garam
full_name: Han, Garam
last_name: Han
- first_name: Changyoung
full_name: Kim, Changyoung
last_name: Kim
- first_name: Woun
full_name: Kang, Woun
last_name: Kang
citation:
ama: 'Hussain T, Oh M, Nauman M, et al. Pressure-induced metal–insulator transitions
in chalcogenide NiS2-Se. Physica B: Condensed Matter. 2018;536:235-238.
doi:10.1016/j.physb.2017.11.032'
apa: 'Hussain, T., Oh, M., Nauman, M., Jo, Y., Han, G., Kim, C., & Kang, W.
(2018). Pressure-induced metal–insulator transitions in chalcogenide NiS2-Se.
Physica B: Condensed Matter. Elsevier. https://doi.org/10.1016/j.physb.2017.11.032'
chicago: 'Hussain, Tayyaba, Myeong-jun Oh, Muhammad Nauman, Younjung Jo, Garam Han,
Changyoung Kim, and Woun Kang. “Pressure-Induced Metal–Insulator Transitions in
Chalcogenide NiS2-Se.” Physica B: Condensed Matter. Elsevier, 2018. https://doi.org/10.1016/j.physb.2017.11.032.'
ieee: 'T. Hussain et al., “Pressure-induced metal–insulator transitions in
chalcogenide NiS2-Se,” Physica B: Condensed Matter, vol. 536. Elsevier,
pp. 235–238, 2018.'
ista: 'Hussain T, Oh M, Nauman M, Jo Y, Han G, Kim C, Kang W. 2018. Pressure-induced
metal–insulator transitions in chalcogenide NiS2-Se. Physica B: Condensed Matter.
536, 235–238.'
mla: 'Hussain, Tayyaba, et al. “Pressure-Induced Metal–Insulator Transitions in
Chalcogenide NiS2-Se.” Physica B: Condensed Matter, vol. 536, Elsevier,
2018, pp. 235–38, doi:10.1016/j.physb.2017.11.032.'
short: 'T. Hussain, M. Oh, M. Nauman, Y. Jo, G. Han, C. Kim, W. Kang, Physica B:
Condensed Matter 536 (2018) 235–238.'
date_created: 2021-02-02T15:52:43Z
date_published: 2018-05-01T00:00:00Z
date_updated: 2021-02-04T07:18:57Z
day: '01'
doi: 10.1016/j.physb.2017.11.032
extern: '1'
intvolume: ' 536'
language:
- iso: eng
month: '05'
oa_version: None
page: 235-238
publication: 'Physica B: Condensed Matter'
publication_identifier:
issn:
- 0921-4526
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: Pressure-induced metal–insulator transitions in chalcogenide NiS2-Se
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 536
year: '2018'
...
---
_id: '913'
abstract:
- lang: eng
text: Coordinated cell polarization in developing tissues is a recurrent theme in
multicellular organisms. In plants, a directional distribution of the plant hormone
auxin is at the core of many developmental programs. A feedback regulation of
auxin on the polarized localization of PIN auxin transporters in individual cells
has been proposed as a self-organizing mechanism for coordinated tissue polarization,
but the molecular mechanisms linking auxin signalling to PIN-dependent auxin transport
remain unknown. We performed a microarray-based approach to find regulators of
the auxin-induced PIN relocation in the Arabidopsis thaliana root. We identified
a subset of a family of phosphatidylinositol transfer proteins (PITP), the PATELLINs
(PATL). Here, we show that PATLs are expressed in partially overlapping cells
types in different tissues going through mitosis or initiating differentiation
programs. PATLs are plasma membrane-associated proteins accumulated in Arabidopsis
embryos, primary roots, lateral root primordia, and developing stomata. Higher
order patl mutants display reduced PIN1 repolarization in response to auxin, shorter
root apical meristem, and drastic defects in embryo and seedling development.
This suggests PATLs redundantly play a crucial role in polarity and patterning
in Arabidopsis.
article_number: jcs.204198
article_processing_charge: No
author:
- first_name: Ricardo
full_name: Tejos, Ricardo
last_name: Tejos
- first_name: Cecilia
full_name: Rodríguez Furlán, Cecilia
last_name: Rodríguez Furlán
- first_name: Maciek
full_name: Adamowski, Maciek
id: 45F536D2-F248-11E8-B48F-1D18A9856A87
last_name: Adamowski
orcid: 0000-0001-6463-5257
- first_name: Michael
full_name: Sauer, Michael
last_name: Sauer
- first_name: Lorena
full_name: Norambuena, Lorena
last_name: Norambuena
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Tejos R, Rodríguez Furlán C, Adamowski M, Sauer M, Norambuena L, Friml J. PATELLINS
are regulators of auxin mediated PIN1 relocation and plant development in Arabidopsis
thaliana. Journal of Cell Science. 2018;131(2). doi:10.1242/jcs.204198
apa: Tejos, R., Rodríguez Furlán, C., Adamowski, M., Sauer, M., Norambuena, L.,
& Friml, J. (2018). PATELLINS are regulators of auxin mediated PIN1 relocation
and plant development in Arabidopsis thaliana. Journal of Cell Science.
Company of Biologists. https://doi.org/10.1242/jcs.204198
chicago: Tejos, Ricardo, Cecilia Rodríguez Furlán, Maciek Adamowski, Michael Sauer,
Lorena Norambuena, and Jiří Friml. “PATELLINS Are Regulators of Auxin Mediated
PIN1 Relocation and Plant Development in Arabidopsis Thaliana.” Journal of
Cell Science. Company of Biologists, 2018. https://doi.org/10.1242/jcs.204198.
ieee: R. Tejos, C. Rodríguez Furlán, M. Adamowski, M. Sauer, L. Norambuena, and
J. Friml, “PATELLINS are regulators of auxin mediated PIN1 relocation and plant
development in Arabidopsis thaliana,” Journal of Cell Science, vol. 131,
no. 2. Company of Biologists, 2018.
ista: Tejos R, Rodríguez Furlán C, Adamowski M, Sauer M, Norambuena L, Friml J.
2018. PATELLINS are regulators of auxin mediated PIN1 relocation and plant development
in Arabidopsis thaliana. Journal of Cell Science. 131(2), jcs. 204198.
mla: Tejos, Ricardo, et al. “PATELLINS Are Regulators of Auxin Mediated PIN1 Relocation
and Plant Development in Arabidopsis Thaliana.” Journal of Cell Science,
vol. 131, no. 2, jcs. 204198, Company of Biologists, 2018, doi:10.1242/jcs.204198.
short: R. Tejos, C. Rodríguez Furlán, M. Adamowski, M. Sauer, L. Norambuena, J.
Friml, Journal of Cell Science 131 (2018).
date_created: 2018-12-11T11:49:10Z
date_published: 2018-01-29T00:00:00Z
date_updated: 2025-05-07T11:12:29Z
day: '29'
ddc:
- '581'
department:
- _id: JiFr
doi: 10.1242/jcs.204198
ec_funded: 1
external_id:
isi:
- '000424842400019'
file:
- access_level: open_access
checksum: bf156c20a4f117b4b932370d54cbac8c
content_type: application/pdf
creator: dernst
date_created: 2019-04-12T08:46:32Z
date_updated: 2020-07-14T12:48:15Z
file_id: '6299'
file_name: 2017_adamowski_PATELLINS_are.pdf
file_size: 14925985
relation: main_file
file_date_updated: 2020-07-14T12:48:15Z
has_accepted_license: '1'
intvolume: ' 131'
isi: 1
issue: '2'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
project:
- _id: 25716A02-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '282300'
name: Polarity and subcellular dynamics in plants
publication: Journal of Cell Science
publication_identifier:
issn:
- '00219533'
publication_status: published
publisher: Company of Biologists
publist_id: '6530'
pubrep_id: '988'
quality_controlled: '1'
scopus_import: '1'
status: public
title: PATELLINS are regulators of auxin mediated PIN1 relocation and plant development
in Arabidopsis thaliana
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 131
year: '2018'
...
---
_id: '9134'
abstract:
- lang: eng
text: Several studies have shown the existence of a critical latitude where the
dissipation of internal tides is strongly enhanced. Internal tides are internal
waves generated by barotropic tidal currents impinging rough topography at the
seafloor. Their dissipation and concomitant diapycnal mixing are believed to be
important for water masses and the large‐scale ocean circulation. The purpose
of this study is to clarify the physical processes at the origin of this strong
latitudinal dependence of tidal energy dissipation. We find that different mechanisms
are involved equatorward and poleward of the critical latitude. Triadic resonant
instabilities are responsible for the dissipation of internal tides equatorward
of the critical latitude. In particular, a dominant triad involving the primary
internal tide and near‐inertial waves is key. At the critical latitude, the peak
of energy dissipation is explained by both increased instability growth rates,
and smaller scales of secondary waves thus more prone to break and dissipate their
energy. Surprisingly, poleward of the critical latitude, the generation of evanescent
waves appears to be crucial. Triadic instabilities have been widely studied, but
the transfer of energy to evanescent waves has received comparatively little attention.
Our work suggests that the nonlinear transfer of energy from the internal tide
to evanescent waves (corresponding to the 2f‐pump mechanism described by Young
et al., 2008, https://doi.org/10.1017/S0022112008001742) is an efficient mechanism
to dissipate internal tide energy near and poleward of the critical latitude.
The theoretical results are confirmed in idealized high‐resolution numerical simulations
of a barotropic M2 tide impinging sinusoidal topography in a linearly stratified
fluid.
article_processing_charge: No
article_type: original
author:
- first_name: O.
full_name: Richet, O.
last_name: Richet
- first_name: J.-M.
full_name: Chomaz, J.-M.
last_name: Chomaz
- first_name: Caroline J
full_name: Muller, Caroline J
id: f978ccb0-3f7f-11eb-b193-b0e2bd13182b
last_name: Muller
orcid: 0000-0001-5836-5350
citation:
ama: 'Richet O, Chomaz J-M, Muller CJ. Internal tide dissipation at topography:
Triadic resonant instability equatorward and evanescent waves poleward of the
critical latitude. Journal of Geophysical Research: Oceans. 2018;123(9):6136-6155.
doi:10.1029/2017jc013591'
apa: 'Richet, O., Chomaz, J.-M., & Muller, C. J. (2018). Internal tide dissipation
at topography: Triadic resonant instability equatorward and evanescent waves poleward
of the critical latitude. Journal of Geophysical Research: Oceans. American
Geophysical Union. https://doi.org/10.1029/2017jc013591'
chicago: 'Richet, O., J.-M. Chomaz, and Caroline J Muller. “Internal Tide Dissipation
at Topography: Triadic Resonant Instability Equatorward and Evanescent Waves Poleward
of the Critical Latitude.” Journal of Geophysical Research: Oceans. American
Geophysical Union, 2018. https://doi.org/10.1029/2017jc013591.'
ieee: 'O. Richet, J.-M. Chomaz, and C. J. Muller, “Internal tide dissipation at
topography: Triadic resonant instability equatorward and evanescent waves poleward
of the critical latitude,” Journal of Geophysical Research: Oceans, vol.
123, no. 9. American Geophysical Union, pp. 6136–6155, 2018.'
ista: 'Richet O, Chomaz J-M, Muller CJ. 2018. Internal tide dissipation at topography:
Triadic resonant instability equatorward and evanescent waves poleward of the
critical latitude. Journal of Geophysical Research: Oceans. 123(9), 6136–6155.'
mla: 'Richet, O., et al. “Internal Tide Dissipation at Topography: Triadic Resonant
Instability Equatorward and Evanescent Waves Poleward of the Critical Latitude.”
Journal of Geophysical Research: Oceans, vol. 123, no. 9, American Geophysical
Union, 2018, pp. 6136–55, doi:10.1029/2017jc013591.'
short: 'O. Richet, J.-M. Chomaz, C.J. Muller, Journal of Geophysical Research: Oceans
123 (2018) 6136–6155.'
date_created: 2021-02-15T14:17:25Z
date_published: 2018-09-01T00:00:00Z
date_updated: 2022-01-24T12:39:03Z
day: '01'
doi: 10.1029/2017jc013591
extern: '1'
intvolume: ' 123'
issue: '9'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1029/2017JC013591
month: '09'
oa: 1
oa_version: Published Version
page: 6136-6155
publication: 'Journal of Geophysical Research: Oceans'
publication_identifier:
issn:
- 2169-9275
publication_status: published
publisher: American Geophysical Union
quality_controlled: '1'
status: public
title: 'Internal tide dissipation at topography: Triadic resonant instability equatorward
and evanescent waves poleward of the critical latitude'
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 123
year: '2018'
...
---
_id: '9135'
abstract:
- lang: eng
text: Idealized simulations of tropical moist convection have revealed that clouds
can spontaneously clump together in a process called self-aggregation. This results
in a state where a moist cloudy region with intense deep convection is surrounded
by extremely dry subsiding air devoid of deep convection. Because of the idealized
settings of the simulations where it was discovered, the relevance of self-aggregation
to the real world is still debated. Here, we show that self-aggregation feedbacks
play a leading-order role in the spontaneous genesis of tropical cyclones in cloud-resolving
simulations. Those feedbacks accelerate the cyclogenesis process by a factor of
2, and the feedbacks contributing to the cyclone formation show qualitative and
quantitative agreement with the self-aggregation process. Once the cyclone is
formed, wind-induced surface heat exchange (WISHE) effects dominate, although
we find that self-aggregation feedbacks have a small but nonnegligible contribution
to the maintenance of the mature cyclone. Our results suggest that self-aggregation,
and the framework developed for its study, can help shed more light into the physical
processes leading to cyclogenesis and cyclone intensification. In particular,
our results point out the importance of the longwave radiative cooling outside
the cyclone.
article_processing_charge: No
article_type: original
author:
- first_name: Caroline J
full_name: Muller, Caroline J
id: f978ccb0-3f7f-11eb-b193-b0e2bd13182b
last_name: Muller
orcid: 0000-0001-5836-5350
- first_name: David M.
full_name: Romps, David M.
last_name: Romps
citation:
ama: Muller CJ, Romps DM. Acceleration of tropical cyclogenesis by self-aggregation
feedbacks. Proceedings of the National Academy of Sciences. 2018;115(12):2930-2935.
doi:10.1073/pnas.1719967115
apa: Muller, C. J., & Romps, D. M. (2018). Acceleration of tropical cyclogenesis
by self-aggregation feedbacks. Proceedings of the National Academy of Sciences.
Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1719967115
chicago: Muller, Caroline J, and David M. Romps. “Acceleration of Tropical Cyclogenesis
by Self-Aggregation Feedbacks.” Proceedings of the National Academy of Sciences.
Proceedings of the National Academy of Sciences, 2018. https://doi.org/10.1073/pnas.1719967115.
ieee: C. J. Muller and D. M. Romps, “Acceleration of tropical cyclogenesis by self-aggregation
feedbacks,” Proceedings of the National Academy of Sciences, vol. 115,
no. 12. Proceedings of the National Academy of Sciences, pp. 2930–2935, 2018.
ista: Muller CJ, Romps DM. 2018. Acceleration of tropical cyclogenesis by self-aggregation
feedbacks. Proceedings of the National Academy of Sciences. 115(12), 2930–2935.
mla: Muller, Caroline J., and David M. Romps. “Acceleration of Tropical Cyclogenesis
by Self-Aggregation Feedbacks.” Proceedings of the National Academy of Sciences,
vol. 115, no. 12, Proceedings of the National Academy of Sciences, 2018, pp. 2930–35,
doi:10.1073/pnas.1719967115.
short: C.J. Muller, D.M. Romps, Proceedings of the National Academy of Sciences
115 (2018) 2930–2935.
date_created: 2021-02-15T14:18:16Z
date_published: 2018-03-20T00:00:00Z
date_updated: 2022-01-24T12:39:49Z
day: '20'
doi: 10.1073/pnas.1719967115
extern: '1'
intvolume: ' 115'
issue: '12'
keyword:
- Multidisciplinary
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1073/pnas.1719967115
month: '03'
oa: 1
oa_version: Published Version
page: 2930-2935
publication: Proceedings of the National Academy of Sciences
publication_identifier:
issn:
- 0027-8424
- 1091-6490
publication_status: published
publisher: Proceedings of the National Academy of Sciences
quality_controlled: '1'
status: public
title: Acceleration of tropical cyclogenesis by self-aggregation feedbacks
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 115
year: '2018'
...
---
_id: '9136'
abstract:
- lang: eng
text: In this study we investigate the scaling of precipitation extremes with temperature
in the Mediterranean region by assessing against observations the present day
and future regional climate simulations performed in the frame of the HyMeX and
MED-CORDEX programs. Over the 1979–2008 period, despite differences in quantitative
precipitation simulation across the various models, the change in precipitation
extremes with respect to temperature is robust and consistent. The spatial variability
of the temperature–precipitation extremes relationship displays a hook shape across
the Mediterranean, with negative slope at high temperatures and a slope following
Clausius–Clapeyron (CC)-scaling at low temperatures. The temperature at which
the slope of the temperature–precipitation extreme relation sharply changes (or
temperature break), ranges from about 20 °C in the western Mediterranean to <10
°C in Greece. In addition, this slope is always negative in the arid regions of
the Mediterranean. The scaling of the simulated precipitation extremes is insensitive
to ocean–atmosphere coupling, while it depends very weakly on the resolution at
high temperatures for short precipitation accumulation times. In future climate
scenario simulations covering the 2070–2100 period, the temperature break shifts
to higher temperatures by a value which is on average the mean regional temperature
change due to global warming. The slope of the simulated future temperature–precipitation
extremes relationship is close to CC-scaling at temperatures below the temperature
break, while at high temperatures, the negative slope is close, but somewhat flatter
or steeper, than in the current climate depending on the model. Overall, models
predict more intense precipitation extremes in the future. Adjusting the temperature–precipitation
extremes relationship in the present climate using the CC law and the temperature
shift in the future allows the recovery of the temperature–precipitation extremes
relationship in the future climate. This implies negligible regional changes of
relative humidity in the future despite the large warming and drying over the
Mediterranean. This suggests that the Mediterranean Sea is the primary source
of moisture which counteracts the drying and warming impacts on relative humidity
in parts of the Mediterranean region.
article_processing_charge: No
article_type: original
author:
- first_name: Philippe
full_name: Drobinski, Philippe
last_name: Drobinski
- first_name: Nicolas Da
full_name: Silva, Nicolas Da
last_name: Silva
- first_name: Gérémy
full_name: Panthou, Gérémy
last_name: Panthou
- first_name: Sophie
full_name: Bastin, Sophie
last_name: Bastin
- first_name: Caroline J
full_name: Muller, Caroline J
id: f978ccb0-3f7f-11eb-b193-b0e2bd13182b
last_name: Muller
orcid: 0000-0001-5836-5350
- first_name: Bodo
full_name: Ahrens, Bodo
last_name: Ahrens
- first_name: Marco
full_name: Borga, Marco
last_name: Borga
- first_name: Dario
full_name: Conte, Dario
last_name: Conte
- first_name: Giorgia
full_name: Fosser, Giorgia
last_name: Fosser
- first_name: Filippo
full_name: Giorgi, Filippo
last_name: Giorgi
- first_name: Ivan
full_name: Güttler, Ivan
last_name: Güttler
- first_name: Vassiliki
full_name: Kotroni, Vassiliki
last_name: Kotroni
- first_name: Laurent
full_name: Li, Laurent
last_name: Li
- first_name: Efrat
full_name: Morin, Efrat
last_name: Morin
- first_name: Bariş
full_name: Önol, Bariş
last_name: Önol
- first_name: Pere
full_name: Quintana-Segui, Pere
last_name: Quintana-Segui
- first_name: Raquel
full_name: Romera, Raquel
last_name: Romera
- first_name: Csaba Zsolt
full_name: Torma, Csaba Zsolt
last_name: Torma
citation:
ama: 'Drobinski P, Silva ND, Panthou G, et al. Scaling precipitation extremes with
temperature in the Mediterranean: Past climate assessment and projection in anthropogenic
scenarios. Climate Dynamics. 2018;51(3):1237-1257. doi:10.1007/s00382-016-3083-x'
apa: 'Drobinski, P., Silva, N. D., Panthou, G., Bastin, S., Muller, C. J., Ahrens,
B., … Torma, C. Z. (2018). Scaling precipitation extremes with temperature in
the Mediterranean: Past climate assessment and projection in anthropogenic scenarios.
Climate Dynamics. Springer Nature. https://doi.org/10.1007/s00382-016-3083-x'
chicago: 'Drobinski, Philippe, Nicolas Da Silva, Gérémy Panthou, Sophie Bastin,
Caroline J Muller, Bodo Ahrens, Marco Borga, et al. “Scaling Precipitation Extremes
with Temperature in the Mediterranean: Past Climate Assessment and Projection
in Anthropogenic Scenarios.” Climate Dynamics. Springer Nature, 2018. https://doi.org/10.1007/s00382-016-3083-x.'
ieee: 'P. Drobinski et al., “Scaling precipitation extremes with temperature
in the Mediterranean: Past climate assessment and projection in anthropogenic
scenarios,” Climate Dynamics, vol. 51, no. 3. Springer Nature, pp. 1237–1257,
2018.'
ista: 'Drobinski P, Silva ND, Panthou G, Bastin S, Muller CJ, Ahrens B, Borga M,
Conte D, Fosser G, Giorgi F, Güttler I, Kotroni V, Li L, Morin E, Önol B, Quintana-Segui
P, Romera R, Torma CZ. 2018. Scaling precipitation extremes with temperature in
the Mediterranean: Past climate assessment and projection in anthropogenic scenarios.
Climate Dynamics. 51(3), 1237–1257.'
mla: 'Drobinski, Philippe, et al. “Scaling Precipitation Extremes with Temperature
in the Mediterranean: Past Climate Assessment and Projection in Anthropogenic
Scenarios.” Climate Dynamics, vol. 51, no. 3, Springer Nature, 2018, pp.
1237–57, doi:10.1007/s00382-016-3083-x.'
short: P. Drobinski, N.D. Silva, G. Panthou, S. Bastin, C.J. Muller, B. Ahrens,
M. Borga, D. Conte, G. Fosser, F. Giorgi, I. Güttler, V. Kotroni, L. Li, E. Morin,
B. Önol, P. Quintana-Segui, R. Romera, C.Z. Torma, Climate Dynamics 51 (2018)
1237–1257.
date_created: 2021-02-15T14:18:53Z
date_published: 2018-08-01T00:00:00Z
date_updated: 2022-01-24T12:40:40Z
day: '01'
doi: 10.1007/s00382-016-3083-x
extern: '1'
intvolume: ' 51'
issue: '3'
keyword:
- Atmospheric Science
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1007/s00382-016-3083-x
month: '08'
oa: 1
oa_version: Published Version
page: 1237-1257
publication: Climate Dynamics
publication_identifier:
issn:
- 0930-7575
- 1432-0894
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: 'Scaling precipitation extremes with temperature in the Mediterranean: Past
climate assessment and projection in anthropogenic scenarios'
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 51
year: '2018'
...