---
_id: '279'
abstract:
- lang: eng
text: 'Background: Natural selection shapes cancer genomes. Previous studies used
signatures of positive selection to identify genes driving malignant transformation.
However, the contribution of negative selection against somatic mutations that
affect essential tumor functions or specific domains remains a controversial topic.
Results: Here, we analyze 7546 individual exomes from 26 tumor types from TCGA
data to explore the portion of the cancer exome under negative selection. Although
we find most of the genes neutrally evolving in a pan-cancer framework, we identify
essential cancer genes and immune-exposed protein regions under significant negative
selection. Moreover, our simulations suggest that the amount of negative selection
is underestimated. We therefore choose an empirical approach to identify genes,
functions, and protein regions under negative selection. We find that expression
and mutation status of negatively selected genes is indicative of patient survival.
Processes that are most strongly conserved are those that play fundamental cellular
roles such as protein synthesis, glucose metabolism, and molecular transport.
Intriguingly, we observe strong signals of selection in the immunopeptidome and
proteins controlling peptide exposition, highlighting the importance of immune
surveillance evasion. Additionally, tumor type-specific immune activity correlates
with the strength of negative selection on human epitopes. Conclusions: In summary,
our results show that negative selection is a hallmark of cell essentiality and
immune response in cancer. The functional domains identified could be exploited
therapeutically, ultimately allowing for the development of novel cancer treatments.'
article_number: '67'
article_processing_charge: No
author:
- first_name: Luis
full_name: Zapata, Luis
last_name: Zapata
- first_name: Oriol
full_name: Pich, Oriol
last_name: Pich
- first_name: Luis
full_name: Serrano, Luis
last_name: Serrano
- first_name: Fyodor
full_name: Kondrashov, Fyodor
id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
last_name: Kondrashov
orcid: 0000-0001-8243-4694
- first_name: Stephan
full_name: Ossowski, Stephan
last_name: Ossowski
- first_name: Martin
full_name: Schaefer, Martin
last_name: Schaefer
citation:
ama: Zapata L, Pich O, Serrano L, Kondrashov F, Ossowski S, Schaefer M. Negative
selection in tumor genome evolution acts on essential cellular functions and the
immunopeptidome. Genome Biology. 2018;19. doi:10.1186/s13059-018-1434-0
apa: Zapata, L., Pich, O., Serrano, L., Kondrashov, F., Ossowski, S., & Schaefer,
M. (2018). Negative selection in tumor genome evolution acts on essential cellular
functions and the immunopeptidome. Genome Biology. BioMed Central. https://doi.org/10.1186/s13059-018-1434-0
chicago: Zapata, Luis, Oriol Pich, Luis Serrano, Fyodor Kondrashov, Stephan Ossowski,
and Martin Schaefer. “Negative Selection in Tumor Genome Evolution Acts on Essential
Cellular Functions and the Immunopeptidome.” Genome Biology. BioMed Central,
2018. https://doi.org/10.1186/s13059-018-1434-0.
ieee: L. Zapata, O. Pich, L. Serrano, F. Kondrashov, S. Ossowski, and M. Schaefer,
“Negative selection in tumor genome evolution acts on essential cellular functions
and the immunopeptidome,” Genome Biology, vol. 19. BioMed Central, 2018.
ista: Zapata L, Pich O, Serrano L, Kondrashov F, Ossowski S, Schaefer M. 2018. Negative
selection in tumor genome evolution acts on essential cellular functions and the
immunopeptidome. Genome Biology. 19, 67.
mla: Zapata, Luis, et al. “Negative Selection in Tumor Genome Evolution Acts on
Essential Cellular Functions and the Immunopeptidome.” Genome Biology,
vol. 19, 67, BioMed Central, 2018, doi:10.1186/s13059-018-1434-0.
short: L. Zapata, O. Pich, L. Serrano, F. Kondrashov, S. Ossowski, M. Schaefer,
Genome Biology 19 (2018).
date_created: 2018-12-11T11:45:35Z
date_published: 2018-05-31T00:00:00Z
date_updated: 2023-09-13T09:01:32Z
day: '31'
ddc:
- '570'
department:
- _id: FyKo
doi: 10.1186/s13059-018-1434-0
ec_funded: 1
external_id:
isi:
- '000433986200001'
file:
- access_level: open_access
checksum: f3e4922486bd9bf1483271bdbed394a7
content_type: application/pdf
creator: dernst
date_created: 2018-12-17T14:05:01Z
date_updated: 2020-07-14T12:45:47Z
file_id: '5708'
file_name: 2018_GenomeBiology_Zapata.pdf
file_size: 1414722
relation: main_file
file_date_updated: 2020-07-14T12:45:47Z
has_accepted_license: '1'
intvolume: ' 19'
isi: 1
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
project:
- _id: 26120F5C-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '335980'
name: Systematic investigation of epistasis in molecular evolution
publication: Genome Biology
publication_status: published
publisher: BioMed Central
publist_id: '7620'
quality_controlled: '1'
related_material:
record:
- id: '9811'
relation: research_data
status: public
- id: '9812'
relation: research_data
status: public
scopus_import: '1'
status: public
title: Negative selection in tumor genome evolution acts on essential cellular functions
and the immunopeptidome
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 19
year: '2018'
...
---
_id: '28'
abstract:
- lang: eng
text: 'This scientific commentary refers to ‘NEGR1 and FGFR2 cooperatively regulate
cortical development and core behaviours related to autism disorders in mice’
by Szczurkowska et al. '
article_processing_charge: No
author:
- first_name: Ximena
full_name: Contreras, Ximena
id: 475990FE-F248-11E8-B48F-1D18A9856A87
last_name: Contreras
- first_name: Simon
full_name: Hippenmeyer, Simon
id: 37B36620-F248-11E8-B48F-1D18A9856A87
last_name: Hippenmeyer
orcid: 0000-0003-2279-1061
citation:
ama: Contreras X, Hippenmeyer S. Incorrect trafficking route leads to autism. Brain
a journal of neurology. 2018;141(9):2542-2544. doi:10.1093/brain/awy218
apa: Contreras, X., & Hippenmeyer, S. (2018). Incorrect trafficking route leads
to autism. Brain a Journal of Neurology. Oxford University Press. https://doi.org/10.1093/brain/awy218
chicago: Contreras, Ximena, and Simon Hippenmeyer. “Incorrect Trafficking Route
Leads to Autism.” Brain a Journal of Neurology. Oxford University Press,
2018. https://doi.org/10.1093/brain/awy218.
ieee: X. Contreras and S. Hippenmeyer, “Incorrect trafficking route leads to autism,”
Brain a journal of neurology, vol. 141, no. 9. Oxford University Press,
pp. 2542–2544, 2018.
ista: Contreras X, Hippenmeyer S. 2018. Incorrect trafficking route leads to autism.
Brain a journal of neurology. 141(9), 2542–2544.
mla: Contreras, Ximena, and Simon Hippenmeyer. “Incorrect Trafficking Route Leads
to Autism.” Brain a Journal of Neurology, vol. 141, no. 9, Oxford University
Press, 2018, pp. 2542–44, doi:10.1093/brain/awy218.
short: X. Contreras, S. Hippenmeyer, Brain a Journal of Neurology 141 (2018) 2542–2544.
date_created: 2018-12-11T11:44:14Z
date_published: 2018-09-01T00:00:00Z
date_updated: 2024-03-25T23:30:23Z
day: '01'
department:
- _id: SiHi
doi: 10.1093/brain/awy218
external_id:
isi:
- '000446548100012'
intvolume: ' 141'
isi: 1
issue: '9'
language:
- iso: eng
month: '09'
oa_version: None
page: 2542 - 2544
publication: Brain a journal of neurology
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
related_material:
record:
- id: '7902'
relation: part_of_dissertation
status: public
scopus_import: '1'
status: public
title: Incorrect trafficking route leads to autism
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 141
year: '2018'
...
---
_id: '280'
abstract:
- lang: eng
text: Flowers have a species-specific functional life span that determines the time
window in which pollination, fertilization and seed set can occur. The stigma
tissue plays a key role in flower receptivity by intercepting pollen and initiating
pollen tube growth toward the ovary. In this article, we show that a developmentally
controlled cell death programme terminates the functional life span of stigma
cells in Arabidopsis. We identified the leaf senescence regulator ORESARA1 (also
known as ANAC092) and the previously uncharacterized KIRA1 (also known as ANAC074)
as partially redundant transcription factors that modulate stigma longevity by
controlling the expression of programmed cell death-associated genes. KIRA1 expression
is sufficient to induce cell death and terminate floral receptivity, whereas lack
of both KIRA1 and ORESARA1 substantially increases stigma life span. Surprisingly,
the extension of stigma longevity is accompanied by only a moderate extension
of flower receptivity, suggesting that additional processes participate in the
control of the flower's receptive life span.
acknowledgement: We gratefully acknowledge funding from the Chinese Scholarship Council
(CSC; project number 201206910025 to Z.G.), the Fonds Wetenschappelijk Onderzoek
(FWO; project number G005112N to A.D.; fellowship number 12I7417N to Z.L.), the
Belgian Federal Science Policy Office (BELSPO; to Y.S.), the Agency for Innovation
by Science and Technology of Belgium (IWT; fellowship number 121110 to M.V.D.),
the Hercules foundation (grant AUGE-09-029 to K.D.), and the ERC StG PROCELLDEATH
(project number 639234 to M.K.N.).
article_processing_charge: No
author:
- first_name: Zhen
full_name: Gao, Zhen
last_name: Gao
- first_name: Anna
full_name: Daneva, Anna
last_name: Daneva
- first_name: Yuliya
full_name: Salanenka, Yuliya
id: 46DAAE7E-F248-11E8-B48F-1D18A9856A87
last_name: Salanenka
- first_name: Matthias
full_name: Van Durme, Matthias
last_name: Van Durme
- first_name: Marlies
full_name: Huysmans, Marlies
last_name: Huysmans
- first_name: Zongcheng
full_name: Lin, Zongcheng
last_name: Lin
- first_name: Freya
full_name: De Winter, Freya
last_name: De Winter
- first_name: Steffen
full_name: Vanneste, Steffen
last_name: Vanneste
- first_name: Mansour
full_name: Karimi, Mansour
last_name: Karimi
- first_name: Jan
full_name: Van De Velde, Jan
last_name: Van De Velde
- first_name: Klaas
full_name: Vandepoele, Klaas
last_name: Vandepoele
- first_name: Davy
full_name: Van De Walle, Davy
last_name: Van De Walle
- first_name: Koen
full_name: Dewettinck, Koen
last_name: Dewettinck
- first_name: Bart
full_name: Lambrecht, Bart
last_name: Lambrecht
- first_name: Moritz
full_name: Nowack, Moritz
last_name: Nowack
citation:
ama: Gao Z, Daneva A, Salanenka Y, et al. KIRA1 and ORESARA1 terminate flower receptivity
by promoting cell death in the stigma of Arabidopsis. Nature Plants. 2018;4(6):365-375.
doi:10.1038/s41477-018-0160-7
apa: Gao, Z., Daneva, A., Salanenka, Y., Van Durme, M., Huysmans, M., Lin, Z., …
Nowack, M. (2018). KIRA1 and ORESARA1 terminate flower receptivity by promoting
cell death in the stigma of Arabidopsis. Nature Plants. Nature Publishing
Group. https://doi.org/10.1038/s41477-018-0160-7
chicago: Gao, Zhen, Anna Daneva, Yuliya Salanenka, Matthias Van Durme, Marlies Huysmans,
Zongcheng Lin, Freya De Winter, et al. “KIRA1 and ORESARA1 Terminate Flower Receptivity
by Promoting Cell Death in the Stigma of Arabidopsis.” Nature Plants. Nature
Publishing Group, 2018. https://doi.org/10.1038/s41477-018-0160-7.
ieee: Z. Gao et al., “KIRA1 and ORESARA1 terminate flower receptivity by
promoting cell death in the stigma of Arabidopsis,” Nature Plants, vol.
4, no. 6. Nature Publishing Group, pp. 365–375, 2018.
ista: Gao Z, Daneva A, Salanenka Y, Van Durme M, Huysmans M, Lin Z, De Winter F,
Vanneste S, Karimi M, Van De Velde J, Vandepoele K, Van De Walle D, Dewettinck
K, Lambrecht B, Nowack M. 2018. KIRA1 and ORESARA1 terminate flower receptivity
by promoting cell death in the stigma of Arabidopsis. Nature Plants. 4(6), 365–375.
mla: Gao, Zhen, et al. “KIRA1 and ORESARA1 Terminate Flower Receptivity by Promoting
Cell Death in the Stigma of Arabidopsis.” Nature Plants, vol. 4, no. 6,
Nature Publishing Group, 2018, pp. 365–75, doi:10.1038/s41477-018-0160-7.
short: Z. Gao, A. Daneva, Y. Salanenka, M. Van Durme, M. Huysmans, Z. Lin, F. De
Winter, S. Vanneste, M. Karimi, J. Van De Velde, K. Vandepoele, D. Van De Walle,
K. Dewettinck, B. Lambrecht, M. Nowack, Nature Plants 4 (2018) 365–375.
date_created: 2018-12-11T11:45:35Z
date_published: 2018-05-28T00:00:00Z
date_updated: 2023-09-13T08:24:17Z
day: '28'
department:
- _id: JiFr
doi: 10.1038/s41477-018-0160-7
external_id:
isi:
- '000435571000017'
intvolume: ' 4'
isi: 1
issue: '6'
language:
- iso: eng
month: '05'
oa_version: None
page: 365 - 375
publication: Nature Plants
publication_status: published
publisher: Nature Publishing Group
publist_id: '7619'
quality_controlled: '1'
scopus_import: '1'
status: public
title: KIRA1 and ORESARA1 terminate flower receptivity by promoting cell death in
the stigma of Arabidopsis
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 4
year: '2018'
...
---
_id: '281'
abstract:
- lang: eng
text: 'Although cells respond specifically to environments, how environmental identity
is encoded intracellularly is not understood. Here, we study this organization
of information in budding yeast by estimating the mutual information between environmental
transitions and the dynamics of nuclear translocation for 10 transcription factors.
Our method of estimation is general, scalable, and based on decoding from single
cells. The dynamics of the transcription factors are necessary to encode the highest
amounts of extracellular information, and we show that information is transduced
through two channels: Generalists (Msn2/4, Tod6 and Dot6, Maf1, and Sfp1) can
encode the nature of multiple stresses, but only if stress is high; specialists
(Hog1, Yap1, and Mig1/2) encode one particular stress, but do so more quickly
and for a wider range of magnitudes. In particular, Dot6 encodes almost as much
information as Msn2, the master regulator of the environmental stress response.
Each transcription factor reports differently, and it is only their collective
behavior that distinguishes between multiple environmental states. Changes in
the dynamics of the localization of transcription factors thus constitute a precise,
distributed internal representation of extracellular change. We predict that such
multidimensional representations are common in cellular decision-making.'
acknowledgement: This work was supported by the Biotechnology and Biological Sciences
Research Council (J.M.J.P., I.F., and P.S.S.), the Engineering and Physical Sciences
Research Council (EPSRC) (A.A.G.), and Austrian Science Fund Grant FWF P28844 (to
G.T.).
article_processing_charge: No
article_type: original
author:
- first_name: Alejandro
full_name: Granados, Alejandro
last_name: Granados
- first_name: Julian
full_name: Pietsch, Julian
last_name: Pietsch
- first_name: Sarah A
full_name: Cepeda Humerez, Sarah A
id: 3DEE19A4-F248-11E8-B48F-1D18A9856A87
last_name: Cepeda Humerez
- first_name: Isebail
full_name: Farquhar, Isebail
last_name: Farquhar
- first_name: Gasper
full_name: Tkacik, Gasper
id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
last_name: Tkacik
orcid: 0000-0002-6699-1455
- first_name: Peter
full_name: Swain, Peter
last_name: Swain
citation:
ama: Granados A, Pietsch J, Cepeda Humerez SA, Farquhar I, Tkačik G, Swain P. Distributed
and dynamic intracellular organization of extracellular information. PNAS.
2018;115(23):6088-6093. doi:10.1073/pnas.1716659115
apa: Granados, A., Pietsch, J., Cepeda Humerez, S. A., Farquhar, I., Tkačik, G.,
& Swain, P. (2018). Distributed and dynamic intracellular organization of
extracellular information. PNAS. National Academy of Sciences. https://doi.org/10.1073/pnas.1716659115
chicago: Granados, Alejandro, Julian Pietsch, Sarah A Cepeda Humerez, Isebail Farquhar,
Gašper Tkačik, and Peter Swain. “Distributed and Dynamic Intracellular Organization
of Extracellular Information.” PNAS. National Academy of Sciences, 2018.
https://doi.org/10.1073/pnas.1716659115.
ieee: A. Granados, J. Pietsch, S. A. Cepeda Humerez, I. Farquhar, G. Tkačik, and
P. Swain, “Distributed and dynamic intracellular organization of extracellular
information,” PNAS, vol. 115, no. 23. National Academy of Sciences, pp.
6088–6093, 2018.
ista: Granados A, Pietsch J, Cepeda Humerez SA, Farquhar I, Tkačik G, Swain P. 2018.
Distributed and dynamic intracellular organization of extracellular information.
PNAS. 115(23), 6088–6093.
mla: Granados, Alejandro, et al. “Distributed and Dynamic Intracellular Organization
of Extracellular Information.” PNAS, vol. 115, no. 23, National Academy
of Sciences, 2018, pp. 6088–93, doi:10.1073/pnas.1716659115.
short: A. Granados, J. Pietsch, S.A. Cepeda Humerez, I. Farquhar, G. Tkačik, P.
Swain, PNAS 115 (2018) 6088–6093.
date_created: 2018-12-11T11:45:35Z
date_published: 2018-06-05T00:00:00Z
date_updated: 2023-09-11T12:58:24Z
day: '05'
department:
- _id: GaTk
doi: 10.1073/pnas.1716659115
external_id:
isi:
- '000434114900071'
pmid:
- '29784812'
intvolume: ' 115'
isi: 1
issue: '23'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.biorxiv.org/content/early/2017/09/21/192039
month: '06'
oa: 1
oa_version: Preprint
page: 6088 - 6093
pmid: 1
project:
- _id: 254E9036-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P28844-B27
name: Biophysics of information processing in gene regulation
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '7618'
quality_controlled: '1'
related_material:
record:
- id: '6473'
relation: part_of_dissertation
status: public
scopus_import: '1'
status: public
title: Distributed and dynamic intracellular organization of extracellular information
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 115
year: '2018'
...
---
_id: '282'
abstract:
- lang: eng
text: Adaptive introgression is common in nature and can be driven by selection
acting on multiple, linked genes. We explore the effects of polygenic selection
on introgression under the infinitesimal model with linkage. This model assumes
that the introgressing block has an effectively infinite number of genes, each
with an infinitesimal effect on the trait under selection. The block is assumed
to introgress under directional selection within a native population that is genetically
homogeneous. We use individual-based simulations and a branching process approximation
to compute various statistics of the introgressing block, and explore how these
depend on parameters such as the map length and initial trait value associated
with the introgressing block, the genetic variability along the block, and the
strength of selection. Our results show that the introgression dynamics of a block
under infinitesimal selection is qualitatively different from the dynamics of
neutral introgression. We also find that in the long run, surviving descendant
blocks are likely to have intermediate lengths, and clarify how the length is
shaped by the interplay between linkage and infinitesimal selection. Our results
suggest that it may be difficult to distinguish introgression of single loci from
that of genomic blocks with multiple, tightly linked and weakly selected loci.
article_processing_charge: No
author:
- first_name: Himani
full_name: Sachdeva, Himani
id: 42377A0A-F248-11E8-B48F-1D18A9856A87
last_name: Sachdeva
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: Sachdeva H, Barton NH. Introgression of a block of genome under infinitesimal
selection. Genetics. 2018;209(4):1279-1303. doi:10.1534/genetics.118.301018
apa: Sachdeva, H., & Barton, N. H. (2018). Introgression of a block of genome
under infinitesimal selection. Genetics. Genetics Society of America. https://doi.org/10.1534/genetics.118.301018
chicago: Sachdeva, Himani, and Nicholas H Barton. “Introgression of a Block of Genome
under Infinitesimal Selection.” Genetics. Genetics Society of America,
2018. https://doi.org/10.1534/genetics.118.301018.
ieee: H. Sachdeva and N. H. Barton, “Introgression of a block of genome under infinitesimal
selection,” Genetics, vol. 209, no. 4. Genetics Society of America, pp.
1279–1303, 2018.
ista: Sachdeva H, Barton NH. 2018. Introgression of a block of genome under infinitesimal
selection. Genetics. 209(4), 1279–1303.
mla: Sachdeva, Himani, and Nicholas H. Barton. “Introgression of a Block of Genome
under Infinitesimal Selection.” Genetics, vol. 209, no. 4, Genetics Society
of America, 2018, pp. 1279–303, doi:10.1534/genetics.118.301018.
short: H. Sachdeva, N.H. Barton, Genetics 209 (2018) 1279–1303.
date_created: 2018-12-11T11:45:36Z
date_published: 2018-08-01T00:00:00Z
date_updated: 2023-09-13T08:22:32Z
day: '01'
department:
- _id: NiBa
doi: 10.1534/genetics.118.301018
external_id:
isi:
- '000440014100020'
intvolume: ' 209'
isi: 1
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.biorxiv.org/content/early/2017/11/30/227082
month: '08'
oa: 1
oa_version: Submitted Version
page: 1279 - 1303
publication: Genetics
publication_status: published
publisher: Genetics Society of America
publist_id: '7617'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Introgression of a block of genome under infinitesimal selection
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 209
year: '2018'
...
---
_id: '283'
abstract:
- lang: eng
text: Light represents the principal signal driving circadian clock entrainment.
However, how light influences the evolution of the clock remains poorly understood.
The cavefish Phreatichthys andruzzii represents a fascinating model to explore
how evolution under extreme aphotic conditions shapes the circadian clock, since
in this species the clock is unresponsive to light. We have previously demonstrated
that loss-of-function mutations targeting non-visual opsins contribute in part
to this blind clock phenotype. Here, we have compared orthologs of two core clock
genes that play a key role in photic entrainment, cry1a and per2, in both zebrafish
and P. andruzzii. We encountered aberrantly spliced variants for the P. andruzzii
per2 transcript. The most abundant transcript encodes a truncated protein lacking
the C-terminal Cry binding domain and incorporating an intronic, transposon-derived
coding sequence. We demonstrate that the transposon insertion leads to a predominantly
cytoplasmic localization of the cavefish Per2 protein in contrast to the zebrafish
ortholog which is distributed in both the nucleus and cytoplasm. Thus, it seems
that during evolution in complete darkness, the photic entrainment pathway of
the circadian clock has been subject to mutation at multiple levels, extending
from opsin photoreceptors to nuclear effectors.
article_number: '8754'
article_processing_charge: No
author:
- first_name: Rosa Maria
full_name: Ceinos, Rosa Maria
last_name: Ceinos
- first_name: Elena
full_name: Frigato, Elena
last_name: Frigato
- first_name: Cristina
full_name: Pagano, Cristina
last_name: Pagano
- first_name: Nadine
full_name: Frohlich, Nadine
last_name: Frohlich
- first_name: Pietro
full_name: Negrini, Pietro
last_name: Negrini
- first_name: Nicola
full_name: Cavallari, Nicola
id: 457160E6-F248-11E8-B48F-1D18A9856A87
last_name: Cavallari
- first_name: Daniela
full_name: Vallone, Daniela
last_name: Vallone
- first_name: Silvia
full_name: Fuselli, Silvia
last_name: Fuselli
- first_name: Cristiano
full_name: Bertolucci, Cristiano
last_name: Bertolucci
- first_name: Nicholas S
full_name: Foulkes, Nicholas S
last_name: Foulkes
citation:
ama: Ceinos RM, Frigato E, Pagano C, et al. Mutations in blind cavefish target the
light regulated circadian clock gene period 2. Scientific Reports. 2018;8(1).
doi:10.1038/s41598-018-27080-2
apa: Ceinos, R. M., Frigato, E., Pagano, C., Frohlich, N., Negrini, P., Cavallari,
N., … Foulkes, N. S. (2018). Mutations in blind cavefish target the light regulated
circadian clock gene period 2. Scientific Reports. Nature Publishing Group.
https://doi.org/10.1038/s41598-018-27080-2
chicago: Ceinos, Rosa Maria, Elena Frigato, Cristina Pagano, Nadine Frohlich, Pietro
Negrini, Nicola Cavallari, Daniela Vallone, Silvia Fuselli, Cristiano Bertolucci,
and Nicholas S Foulkes. “Mutations in Blind Cavefish Target the Light Regulated
Circadian Clock Gene Period 2.” Scientific Reports. Nature Publishing Group,
2018. https://doi.org/10.1038/s41598-018-27080-2.
ieee: R. M. Ceinos et al., “Mutations in blind cavefish target the light
regulated circadian clock gene period 2,” Scientific Reports, vol. 8, no.
1. Nature Publishing Group, 2018.
ista: Ceinos RM, Frigato E, Pagano C, Frohlich N, Negrini P, Cavallari N, Vallone
D, Fuselli S, Bertolucci C, Foulkes NS. 2018. Mutations in blind cavefish target
the light regulated circadian clock gene period 2. Scientific Reports. 8(1), 8754.
mla: Ceinos, Rosa Maria, et al. “Mutations in Blind Cavefish Target the Light Regulated
Circadian Clock Gene Period 2.” Scientific Reports, vol. 8, no. 1, 8754,
Nature Publishing Group, 2018, doi:10.1038/s41598-018-27080-2.
short: R.M. Ceinos, E. Frigato, C. Pagano, N. Frohlich, P. Negrini, N. Cavallari,
D. Vallone, S. Fuselli, C. Bertolucci, N.S. Foulkes, Scientific Reports 8 (2018).
date_created: 2018-12-11T11:45:36Z
date_published: 2018-06-08T00:00:00Z
date_updated: 2023-09-13T08:59:27Z
day: '08'
ddc:
- '570'
department:
- _id: EvBe
doi: 10.1038/s41598-018-27080-2
external_id:
isi:
- '000434640800008'
file:
- access_level: open_access
checksum: 9c3942d772f84f3df032ffde0ed9a8ea
content_type: application/pdf
creator: dernst
date_created: 2018-12-17T13:04:46Z
date_updated: 2020-07-14T12:45:49Z
file_id: '5707'
file_name: 2018_ScientificReports_Ceinos.pdf
file_size: 1855324
relation: main_file
file_date_updated: 2020-07-14T12:45:49Z
has_accepted_license: '1'
intvolume: ' 8'
isi: 1
issue: '1'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
publication: Scientific Reports
publication_status: published
publisher: Nature Publishing Group
publist_id: '7616'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Mutations in blind cavefish target the light regulated circadian clock gene
period 2
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 8
year: '2018'
...
---
_id: '284'
abstract:
- lang: eng
text: "Borel probability measures living on metric spaces are fundamental\r\nmathematical
objects. There are several meaningful distance functions that make the collection
of the probability measures living on a certain space a metric space. We are interested
in the description of the structure of the isometries of such metric spaces. We
overview some of the recent results of the topic and we also provide some new
ones concerning the Wasserstein distance. More specifically, we consider the space
of all Borel probability measures on the unit sphere of a Euclidean space endowed
with the Wasserstein metric W_p for arbitrary p >= 1, and we show that the
action of a Wasserstein isometry on the set of Dirac measures is induced by an
isometry of the underlying unit sphere."
acknowledgement: The author was supported by the ISTFELLOW program of the Institute
of Science and Technol- ogy Austria (project code IC1027FELL01) and partially supported
by the Hungarian National Research, Development and Innovation Office, NKFIH (grant
no. K124152).
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Daniel
full_name: Virosztek, Daniel
id: 48DB45DA-F248-11E8-B48F-1D18A9856A87
last_name: Virosztek
orcid: 0000-0003-1109-5511
citation:
ama: Virosztek D. Maps on probability measures preserving certain distances - a
survey and some new results. Acta Scientiarum Mathematicarum. 2018;84(1-2):65-80.
doi:10.14232/actasm-018-753-y
apa: Virosztek, D. (2018). Maps on probability measures preserving certain distances
- a survey and some new results. Acta Scientiarum Mathematicarum. Springer
Nature. https://doi.org/10.14232/actasm-018-753-y
chicago: Virosztek, Daniel. “Maps on Probability Measures Preserving Certain Distances
- a Survey and Some New Results.” Acta Scientiarum Mathematicarum. Springer
Nature, 2018. https://doi.org/10.14232/actasm-018-753-y.
ieee: D. Virosztek, “Maps on probability measures preserving certain distances -
a survey and some new results,” Acta Scientiarum Mathematicarum, vol. 84,
no. 1–2. Springer Nature, pp. 65–80, 2018.
ista: Virosztek D. 2018. Maps on probability measures preserving certain distances
- a survey and some new results. Acta Scientiarum Mathematicarum. 84(1–2), 65–80.
mla: Virosztek, Daniel. “Maps on Probability Measures Preserving Certain Distances
- a Survey and Some New Results.” Acta Scientiarum Mathematicarum, vol.
84, no. 1–2, Springer Nature, 2018, pp. 65–80, doi:10.14232/actasm-018-753-y.
short: D. Virosztek, Acta Scientiarum Mathematicarum 84 (2018) 65–80.
date_created: 2018-12-11T11:45:36Z
date_published: 2018-06-04T00:00:00Z
date_updated: 2023-10-16T10:29:22Z
day: '04'
department:
- _id: LaEr
doi: 10.14232/actasm-018-753-y
ec_funded: 1
external_id:
arxiv:
- '1802.03305'
intvolume: ' 84'
issue: 1-2
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1802.03305
month: '06'
oa: 1
oa_version: Preprint
page: 65 - 80
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: Acta Scientiarum Mathematicarum
publication_identifier:
eissn:
- 2064-8316
issn:
- 0001-6969
publication_status: published
publisher: Springer Nature
publist_id: '7615'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Maps on probability measures preserving certain distances - a survey and some
new results
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 84
year: '2018'
...
---
_id: '285'
abstract:
- lang: eng
text: In graph theory, as well as in 3-manifold topology, there exist several width-type
parameters to describe how "simple" or "thin" a given graph
or 3-manifold is. These parameters, such as pathwidth or treewidth for graphs,
or the concept of thin position for 3-manifolds, play an important role when studying
algorithmic problems; in particular, there is a variety of problems in computational
3-manifold topology - some of them known to be computationally hard in general
- that become solvable in polynomial time as soon as the dual graph of the input
triangulation has bounded treewidth. In view of these algorithmic results, it
is natural to ask whether every 3-manifold admits a triangulation of bounded treewidth.
We show that this is not the case, i.e., that there exists an infinite family
of closed 3-manifolds not admitting triangulations of bounded pathwidth or treewidth
(the latter implies the former, but we present two separate proofs). We derive
these results from work of Agol and of Scharlemann and Thompson, by exhibiting
explicit connections between the topology of a 3-manifold M on the one hand and
width-type parameters of the dual graphs of triangulations of M on the other hand,
answering a question that had been raised repeatedly by researchers in computational
3-manifold topology. In particular, we show that if a closed, orientable, irreducible,
non-Haken 3-manifold M has a triangulation of treewidth (resp. pathwidth) k then
the Heegaard genus of M is at most 48(k+1) (resp. 4(3k+1)).
acknowledgement: Research of the second author was supported by the Einstein Foundation
(project “Einstein Visiting Fellow Santos”) and by the Simons Foundation (“Simons
Visiting Professors” program).
alternative_title:
- LIPIcs
article_number: '46'
article_processing_charge: No
arxiv: 1
author:
- first_name: Kristóf
full_name: Huszár, Kristóf
id: 33C26278-F248-11E8-B48F-1D18A9856A87
last_name: Huszár
orcid: 0000-0002-5445-5057
- first_name: Jonathan
full_name: Spreer, Jonathan
last_name: Spreer
- first_name: Uli
full_name: Wagner, Uli
id: 36690CA2-F248-11E8-B48F-1D18A9856A87
last_name: Wagner
orcid: 0000-0002-1494-0568
citation:
ama: 'Huszár K, Spreer J, Wagner U. On the treewidth of triangulated 3-manifolds.
In: Vol 99. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2018. doi:10.4230/LIPIcs.SoCG.2018.46'
apa: 'Huszár, K., Spreer, J., & Wagner, U. (2018). On the treewidth of triangulated
3-manifolds (Vol. 99). Presented at the SoCG: Symposium on Computational Geometry,
Budapest, Hungary: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. https://doi.org/10.4230/LIPIcs.SoCG.2018.46'
chicago: Huszár, Kristóf, Jonathan Spreer, and Uli Wagner. “On the Treewidth of
Triangulated 3-Manifolds,” Vol. 99. Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
2018. https://doi.org/10.4230/LIPIcs.SoCG.2018.46.
ieee: 'K. Huszár, J. Spreer, and U. Wagner, “On the treewidth of triangulated 3-manifolds,”
presented at the SoCG: Symposium on Computational Geometry, Budapest, Hungary,
2018, vol. 99.'
ista: 'Huszár K, Spreer J, Wagner U. 2018. On the treewidth of triangulated 3-manifolds.
SoCG: Symposium on Computational Geometry, LIPIcs, vol. 99, 46.'
mla: Huszár, Kristóf, et al. On the Treewidth of Triangulated 3-Manifolds.
Vol. 99, 46, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2018, doi:10.4230/LIPIcs.SoCG.2018.46.
short: K. Huszár, J. Spreer, U. Wagner, in:, Schloss Dagstuhl - Leibniz-Zentrum
für Informatik, 2018.
conference:
end_date: 2018-06-14
location: Budapest, Hungary
name: 'SoCG: Symposium on Computational Geometry'
start_date: 2018-06-11
date_created: 2018-12-11T11:45:37Z
date_published: 2018-06-01T00:00:00Z
date_updated: 2023-09-06T11:13:41Z
day: '01'
ddc:
- '516'
- '000'
department:
- _id: UlWa
doi: 10.4230/LIPIcs.SoCG.2018.46
external_id:
arxiv:
- '1712.00434'
file:
- access_level: open_access
checksum: 530d084116778135d5bffaa317479cac
content_type: application/pdf
creator: dernst
date_created: 2018-12-17T15:32:38Z
date_updated: 2020-07-14T12:45:51Z
file_id: '5713'
file_name: 2018_LIPIcs_Huszar.pdf
file_size: 642522
relation: main_file
file_date_updated: 2020-07-14T12:45:51Z
has_accepted_license: '1'
intvolume: ' 99'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Submitted Version
publication_identifier:
issn:
- '18688969'
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
publist_id: '7614'
quality_controlled: '1'
related_material:
record:
- id: '7093'
relation: later_version
status: public
scopus_import: 1
status: public
title: On the treewidth of triangulated 3-manifolds
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 99
year: '2018'
...
---
_id: '286'
abstract:
- lang: eng
text: 'Pedigree and sibship reconstruction are important methods in quantifying
relationships and fitness of individuals in natural populations. Current methods
employ a Markov chain-based algorithm to explore plausible possible pedigrees
iteratively. This provides accurate results, but is time-consuming. Here, we develop
a method to infer sibship and paternity relationships from half-sibling arrays
of known maternity using hierarchical clustering. Given 50 or more unlinked SNP
markers and empirically derived error rates, the method performs as well as the
widely used package Colony, but is faster by two orders of magnitude. Using simulations,
we show that the method performs well across contrasting mating scenarios, even
when samples are large. We then apply the method to open-pollinated arrays of
the snapdragon Antirrhinum majus and find evidence for a high degree of multiple
mating. Although we focus on diploid SNP data, the method does not depend on marker
type and as such has broad applications in nonmodel systems. '
acknowledgement: 'ERC, Grant/Award Number: 250152'
article_processing_charge: No
author:
- first_name: Thomas
full_name: Ellis, Thomas
id: 3153D6D4-F248-11E8-B48F-1D18A9856A87
last_name: Ellis
orcid: 0000-0002-8511-0254
- first_name: David
full_name: Field, David
id: 419049E2-F248-11E8-B48F-1D18A9856A87
last_name: Field
orcid: 0000-0002-4014-8478
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: Ellis T, Field D, Barton NH. Efficient inference of paternity and sibship inference
given known maternity via hierarchical clustering. Molecular Ecology Resources.
2018;18(5):988-999. doi:10.1111/1755-0998.12782
apa: Ellis, T., Field, D., & Barton, N. H. (2018). Efficient inference of paternity
and sibship inference given known maternity via hierarchical clustering. Molecular
Ecology Resources. Wiley. https://doi.org/10.1111/1755-0998.12782
chicago: Ellis, Thomas, David Field, and Nicholas H Barton. “Efficient Inference
of Paternity and Sibship Inference given Known Maternity via Hierarchical Clustering.”
Molecular Ecology Resources. Wiley, 2018. https://doi.org/10.1111/1755-0998.12782.
ieee: T. Ellis, D. Field, and N. H. Barton, “Efficient inference of paternity and
sibship inference given known maternity via hierarchical clustering,” Molecular
Ecology Resources, vol. 18, no. 5. Wiley, pp. 988–999, 2018.
ista: Ellis T, Field D, Barton NH. 2018. Efficient inference of paternity and sibship
inference given known maternity via hierarchical clustering. Molecular Ecology
Resources. 18(5), 988–999.
mla: Ellis, Thomas, et al. “Efficient Inference of Paternity and Sibship Inference
given Known Maternity via Hierarchical Clustering.” Molecular Ecology Resources,
vol. 18, no. 5, Wiley, 2018, pp. 988–99, doi:10.1111/1755-0998.12782.
short: T. Ellis, D. Field, N.H. Barton, Molecular Ecology Resources 18 (2018) 988–999.
date_created: 2018-12-11T11:45:37Z
date_published: 2018-09-01T00:00:00Z
date_updated: 2025-05-28T11:42:43Z
day: '01'
department:
- _id: NiBa
doi: 10.1111/1755-0998.12782
ec_funded: 1
external_id:
isi:
- '000441753000007'
intvolume: ' 18'
isi: 1
issue: '5'
language:
- iso: eng
month: '09'
oa_version: None
page: 988 - 999
project:
- _id: 25B07788-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '250152'
name: Limits to selection in biology and in evolutionary computation
publication: Molecular Ecology Resources
publication_status: published
publisher: Wiley
quality_controlled: '1'
related_material:
record:
- id: '5583'
relation: popular_science
status: public
scopus_import: '1'
status: public
title: Efficient inference of paternity and sibship inference given known maternity
via hierarchical clustering
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 18
year: '2018'
...
---
_id: '287'
abstract:
- lang: eng
text: In this paper, we discuss biological effects of electromagnetic (EM) fields
in the context of cancer biology. In particular, we review the nanomechanical
properties of microtubules (MTs), the latter being one of the most successful
targets for cancer therapy. We propose an investigation on the coupling of electromagnetic
radiation to mechanical vibrations of MTs as an important basis for biological
and medical applications. In our opinion, optomechanical methods can accurately
monitor and control the mechanical properties of isolated MTs in a liquid environment.
Consequently, studying nanomechanical properties of MTs may give useful information
for future applications to diagnostic and therapeutic technologies involving non-invasive
externally applied physical fields. For example, electromagnetic fields or high
intensity ultrasound can be used therapeutically avoiding harmful side effects
of chemotherapeutic agents or classical radiation therapy.
acknowledgement: The work of SB has been supported by the European Unions Horizon
2020 research and innovation program under the Marie Sklodowska Curie grant agreement
No MSC-IF 707438 SUPEREOM. JAT gratefully acknowledges funding support from NSERC
(Canada) for his research. MC acknowledges support from the Czech Science Foundation,
projects 15-17102S and 17-11898S and he participates in COST Action BM1309, CA15211
and bilateral exchange project between Czech and Slovak Academies of Sciences, SAV-15-22.
article_processing_charge: No
author:
- first_name: Vahid
full_name: Salari, Vahid
last_name: Salari
- first_name: Shabir
full_name: Barzanjeh, Shabir
id: 2D25E1F6-F248-11E8-B48F-1D18A9856A87
last_name: Barzanjeh
orcid: 0000-0003-0415-1423
- first_name: Michal
full_name: Cifra, Michal
last_name: Cifra
- first_name: Christoph
full_name: Simon, Christoph
last_name: Simon
- first_name: Felix
full_name: Scholkmann, Felix
last_name: Scholkmann
- first_name: Zahra
full_name: Alirezaei, Zahra
last_name: Alirezaei
- first_name: Jack
full_name: Tuszynski, Jack
last_name: Tuszynski
citation:
ama: Salari V, Barzanjeh S, Cifra M, et al. Electromagnetic fields and optomechanics
In cancer diagnostics and treatment. Frontiers in Bioscience - Landmark.
2018;23(8):1391-1406. doi:10.2741/4651
apa: Salari, V., Barzanjeh, S., Cifra, M., Simon, C., Scholkmann, F., Alirezaei,
Z., & Tuszynski, J. (2018). Electromagnetic fields and optomechanics In cancer
diagnostics and treatment. Frontiers in Bioscience - Landmark. Frontiers
in Bioscience. https://doi.org/10.2741/4651
chicago: Salari, Vahid, Shabir Barzanjeh, Michal Cifra, Christoph Simon, Felix Scholkmann,
Zahra Alirezaei, and Jack Tuszynski. “Electromagnetic Fields and Optomechanics
In Cancer Diagnostics and Treatment.” Frontiers in Bioscience - Landmark.
Frontiers in Bioscience, 2018. https://doi.org/10.2741/4651.
ieee: V. Salari et al., “Electromagnetic fields and optomechanics In cancer
diagnostics and treatment,” Frontiers in Bioscience - Landmark, vol. 23,
no. 8. Frontiers in Bioscience, pp. 1391–1406, 2018.
ista: Salari V, Barzanjeh S, Cifra M, Simon C, Scholkmann F, Alirezaei Z, Tuszynski
J. 2018. Electromagnetic fields and optomechanics In cancer diagnostics and treatment.
Frontiers in Bioscience - Landmark. 23(8), 1391–1406.
mla: Salari, Vahid, et al. “Electromagnetic Fields and Optomechanics In Cancer Diagnostics
and Treatment.” Frontiers in Bioscience - Landmark, vol. 23, no. 8, Frontiers
in Bioscience, 2018, pp. 1391–406, doi:10.2741/4651.
short: V. Salari, S. Barzanjeh, M. Cifra, C. Simon, F. Scholkmann, Z. Alirezaei,
J. Tuszynski, Frontiers in Bioscience - Landmark 23 (2018) 1391–1406.
date_created: 2018-12-11T11:45:37Z
date_published: 2018-03-01T00:00:00Z
date_updated: 2023-09-11T13:38:14Z
day: '01'
department:
- _id: JoFi
doi: 10.2741/4651
ec_funded: 1
external_id:
isi:
- '000439042800001'
pmid:
- '29293441'
intvolume: ' 23'
isi: 1
issue: '8'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.bioscience.org/2018/v23/af/4651/fulltext.htm
month: '03'
oa: 1
oa_version: Submitted Version
page: 1391 - 1406
pmid: 1
project:
- _id: 258047B6-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '707438'
name: 'Microwave-to-Optical Quantum Link: Quantum Teleportation and Quantum Illumination
with cavity Optomechanics SUPEREOM'
publication: Frontiers in Bioscience - Landmark
publication_status: published
publisher: Frontiers in Bioscience
quality_controlled: '1'
scopus_import: '1'
status: public
title: Electromagnetic fields and optomechanics In cancer diagnostics and treatment
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 23
year: '2018'
...
---
_id: '288'
abstract:
- lang: eng
text: Recent lineage tracing studies have revealed that mammary gland homeostasis
relies on unipotent stem cells. However, whether and when lineage restriction
occurs during embryonic mammary development, and which signals orchestrate cell
fate specification, remain unknown. Using a combination of in vivo clonal analysis
with whole mount immunofluorescence and mathematical modelling of clonal dynamics,
we found that embryonic multipotent mammary cells become lineage-restricted surprisingly
early in development, with evidence for unipotency as early as E12.5 and no statistically
discernable bipotency after E15.5. To gain insights into the mechanisms governing
the switch from multipotency to unipotency, we used gain-of-function Notch1 mice
and demonstrated that Notch activation cell autonomously dictates luminal cell
fate specification to both embryonic and basally committed mammary cells. These
functional studies have important implications for understanding the signals underlying
cell plasticity and serve to clarify how reactivation of embryonic programs in
adult cells can lead to cancer.
article_processing_charge: No
article_type: original
author:
- first_name: Anna
full_name: Lilja, Anna
last_name: Lilja
- first_name: Veronica
full_name: Rodilla, Veronica
last_name: Rodilla
- first_name: Mathilde
full_name: Huyghe, Mathilde
last_name: Huyghe
- first_name: Edouard B
full_name: Hannezo, Edouard B
id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
last_name: Hannezo
orcid: 0000-0001-6005-1561
- first_name: Camille
full_name: Landragin, Camille
last_name: Landragin
- first_name: Olivier
full_name: Renaud, Olivier
last_name: Renaud
- first_name: Olivier
full_name: Leroy, Olivier
last_name: Leroy
- first_name: Steffen
full_name: Rulands, Steffen
last_name: Rulands
- first_name: Benjamin
full_name: Simons, Benjamin
last_name: Simons
- first_name: Silvia
full_name: Fré, Silvia
last_name: Fré
citation:
ama: Lilja A, Rodilla V, Huyghe M, et al. Clonal analysis of Notch1-expressing cells
reveals the existence of unipotent stem cells that retain long-term plasticity
in the embryonic mammary gland. Nature Cell Biology. 2018;20(6):677-687.
doi:10.1038/s41556-018-0108-1
apa: Lilja, A., Rodilla, V., Huyghe, M., Hannezo, E. B., Landragin, C., Renaud,
O., … Fré, S. (2018). Clonal analysis of Notch1-expressing cells reveals the existence
of unipotent stem cells that retain long-term plasticity in the embryonic mammary
gland. Nature Cell Biology. Nature Publishing Group. https://doi.org/10.1038/s41556-018-0108-1
chicago: Lilja, Anna, Veronica Rodilla, Mathilde Huyghe, Edouard B Hannezo, Camille
Landragin, Olivier Renaud, Olivier Leroy, Steffen Rulands, Benjamin Simons, and
Silvia Fré. “Clonal Analysis of Notch1-Expressing Cells Reveals the Existence
of Unipotent Stem Cells That Retain Long-Term Plasticity in the Embryonic Mammary
Gland.” Nature Cell Biology. Nature Publishing Group, 2018. https://doi.org/10.1038/s41556-018-0108-1.
ieee: A. Lilja et al., “Clonal analysis of Notch1-expressing cells reveals
the existence of unipotent stem cells that retain long-term plasticity in the
embryonic mammary gland,” Nature Cell Biology, vol. 20, no. 6. Nature Publishing
Group, pp. 677–687, 2018.
ista: Lilja A, Rodilla V, Huyghe M, Hannezo EB, Landragin C, Renaud O, Leroy O,
Rulands S, Simons B, Fré S. 2018. Clonal analysis of Notch1-expressing cells reveals
the existence of unipotent stem cells that retain long-term plasticity in the
embryonic mammary gland. Nature Cell Biology. 20(6), 677–687.
mla: Lilja, Anna, et al. “Clonal Analysis of Notch1-Expressing Cells Reveals the
Existence of Unipotent Stem Cells That Retain Long-Term Plasticity in the Embryonic
Mammary Gland.” Nature Cell Biology, vol. 20, no. 6, Nature Publishing
Group, 2018, pp. 677–87, doi:10.1038/s41556-018-0108-1.
short: A. Lilja, V. Rodilla, M. Huyghe, E.B. Hannezo, C. Landragin, O. Renaud, O.
Leroy, S. Rulands, B. Simons, S. Fré, Nature Cell Biology 20 (2018) 677–687.
date_created: 2018-12-11T11:45:38Z
date_published: 2018-05-21T00:00:00Z
date_updated: 2023-09-11T12:44:08Z
day: '21'
department:
- _id: EdHa
doi: 10.1038/s41556-018-0108-1
external_id:
isi:
- '000433237300003'
pmid:
- '29784917'
intvolume: ' 20'
isi: 1
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984964
month: '05'
oa: 1
oa_version: Submitted Version
page: 677 - 687
pmid: 1
publication: Nature Cell Biology
publication_status: published
publisher: Nature Publishing Group
publist_id: '7594'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Clonal analysis of Notch1-expressing cells reveals the existence of unipotent
stem cells that retain long-term plasticity in the embryonic mammary gland
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 20
year: '2018'
...
---
_id: '289'
abstract:
- lang: eng
text: We report on quantum capacitance measurements of high quality, graphite- and
hexagonal boron nitride encapsulated Bernal stacked trilayer graphene devices.
At zero applied magnetic field, we observe a number of electron density- and electrical
displacement-tuned features in the electronic compressibility associated with
changes in Fermi surface topology. At high displacement field and low density,
strong trigonal warping gives rise to emergent Dirac gullies centered near the
corners of the hexagonal Brillouin and related by three fold rotation symmetry.
At low magnetic fields of B=1.25~T, the gullies manifest as a change in the degeneracy
of the Landau levels from two to three. Weak incompressible states are also observed
at integer filling within these triplets Landau levels, which a Hartree-Fock analysis
indicates are associated with Coulomb-driven nematic phases that spontaneously
break rotation symmetry.
acknowledgement: The experimental work at UCSB was funded by the National Science
Foundation under Grant No. DMR- 1654186. Work at Columbia was supported by the National
Science Foundation under Grant No. DMR- 1507788. K. W. and T. T. acknowledge support
from the Elemental Strategy Initiative conducted by the Ministry of Education, Culture,
Sports, Science and Technology, Japan, and the Japan Society for the Promotion of
Science KAKENHI Grant No. JP15K21722. E. M. S. acknowledges the support of the Elings
Fellowship from the California Nanosystems Institute at the University of California,
Santa Barbara. A. F. Y. acknowledges the support of the David and Lucile Packard
foundation and the Sloan Foundation. Measurements made use of a dilution refrigerator
funded through the Major Research Instrumentation program of the U.S. National Science
Foundation under Grant No. DMR- 1531389, and the MRL Shared Experimental Facilities,
which are supported by the MRSEC Program of the U.S. National Science Foundation
under Grant No. DMR- 1720256.
article_number: '167601'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Alexander
full_name: Zibrov, Alexander
last_name: Zibrov
- first_name: Rao
full_name: Peng, Rao
id: 47C23AC6-02D0-11E9-BD0E-99399A5D3DEB
last_name: Peng
orcid: 0000-0003-1250-0021
- first_name: Carlos
full_name: Kometter, Carlos
last_name: Kometter
- first_name: Jia
full_name: Li, Jia
last_name: Li
- first_name: Cory
full_name: Dean, Cory
last_name: Dean
- first_name: Takashi
full_name: Taniguchi, Takashi
last_name: Taniguchi
- first_name: Kenji
full_name: Watanabe, Kenji
last_name: Watanabe
- first_name: Maksym
full_name: Serbyn, Maksym
id: 47809E7E-F248-11E8-B48F-1D18A9856A87
last_name: Serbyn
orcid: 0000-0002-2399-5827
- first_name: Andrea
full_name: Young, Andrea
last_name: Young
citation:
ama: Zibrov A, Rao P, Kometter C, et al. Emergent dirac gullies and gully-symmetry-breaking
quantum hall states in ABA trilayer graphene. Physical Review Letters.
2018;121(16). doi:10.1103/PhysRevLett.121.167601
apa: Zibrov, A., Rao, P., Kometter, C., Li, J., Dean, C., Taniguchi, T., … Young,
A. (2018). Emergent dirac gullies and gully-symmetry-breaking quantum hall states
in ABA trilayer graphene. Physical Review Letters. American Physical Society.
https://doi.org/10.1103/PhysRevLett.121.167601
chicago: Zibrov, Alexander, Peng Rao, Carlos Kometter, Jia Li, Cory Dean, Takashi
Taniguchi, Kenji Watanabe, Maksym Serbyn, and Andrea Young. “Emergent Dirac Gullies
and Gully-Symmetry-Breaking Quantum Hall States in ABA Trilayer Graphene.” Physical
Review Letters. American Physical Society, 2018. https://doi.org/10.1103/PhysRevLett.121.167601.
ieee: A. Zibrov et al., “Emergent dirac gullies and gully-symmetry-breaking
quantum hall states in ABA trilayer graphene,” Physical Review Letters,
vol. 121, no. 16. American Physical Society, 2018.
ista: Zibrov A, Rao P, Kometter C, Li J, Dean C, Taniguchi T, Watanabe K, Serbyn
M, Young A. 2018. Emergent dirac gullies and gully-symmetry-breaking quantum hall
states in ABA trilayer graphene. Physical Review Letters. 121(16), 167601.
mla: Zibrov, Alexander, et al. “Emergent Dirac Gullies and Gully-Symmetry-Breaking
Quantum Hall States in ABA Trilayer Graphene.” Physical Review Letters,
vol. 121, no. 16, 167601, American Physical Society, 2018, doi:10.1103/PhysRevLett.121.167601.
short: A. Zibrov, P. Rao, C. Kometter, J. Li, C. Dean, T. Taniguchi, K. Watanabe,
M. Serbyn, A. Young, Physical Review Letters 121 (2018).
date_created: 2018-12-11T11:45:38Z
date_published: 2018-10-19T00:00:00Z
date_updated: 2023-09-11T13:39:50Z
day: '19'
department:
- _id: MaSe
doi: 10.1103/PhysRevLett.121.167601
external_id:
arxiv:
- '1805.01038'
isi:
- '000447307500007'
intvolume: ' 121'
isi: 1
issue: '16'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1805.01038
month: '10'
oa: 1
oa_version: Preprint
publication: Physical Review Letters
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Emergent dirac gullies and gully-symmetry-breaking quantum hall states in ABA
trilayer graphene
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 121
year: '2018'
...
---
_id: '29'
abstract:
- lang: eng
text: Social insects have evolved enormous capacities to collectively build nests
and defend their colonies against both predators and pathogens. The latter is
achieved by a combination of individual immune responses and sophisticated collective
behavioral and organizational disease defenses, that is, social immunity. We investigated
how the presence or absence of these social defense lines affects individual-level
immunity in ant queens after bacterial infection. To this end, we injected queens
of the ant Linepithema humile with a mix of gram+ and gram− bacteria or a control
solution, reared them either with workers or alone and analyzed their gene expression
patterns at 2, 4, 8, and 12 hr post-injection, using RNA-seq. This allowed us
to test for the effect of bacterial infection, social context, as well as the
interaction between the two over the course of infection and raising of an immune
response. We found that social isolation per se affected queen gene expression
for metabolism genes, but not for immune genes. When infected, queens reared with
and without workers up-regulated similar numbers of innate immune genes revealing
activation of Toll and Imd signaling pathways and melanization. Interestingly,
however, they mostly regulated different genes along the pathways and showed a
different pattern of overall gene up-regulation or down-regulation. Hence, we
can conclude that the absence of workers does not compromise the onset of an individual
immune response by the queens, but that the social environment impacts the route
of the individual innate immune responses.
article_processing_charge: No
author:
- first_name: Lumi
full_name: Viljakainen, Lumi
last_name: Viljakainen
- first_name: Jaana
full_name: Jurvansuu, Jaana
last_name: Jurvansuu
- first_name: Ida
full_name: Holmberg, Ida
last_name: Holmberg
- first_name: Tobias
full_name: Pamminger, Tobias
last_name: Pamminger
- first_name: Silvio
full_name: Erler, Silvio
last_name: Erler
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
citation:
ama: Viljakainen L, Jurvansuu J, Holmberg I, Pamminger T, Erler S, Cremer S. Social
environment affects the transcriptomic response to bacteria in ant queens. Ecology
and Evolution. 2018;8(22):11031-11070. doi:10.1002/ece3.4573
apa: Viljakainen, L., Jurvansuu, J., Holmberg, I., Pamminger, T., Erler, S., &
Cremer, S. (2018). Social environment affects the transcriptomic response to bacteria
in ant queens. Ecology and Evolution. Wiley. https://doi.org/10.1002/ece3.4573
chicago: Viljakainen, Lumi, Jaana Jurvansuu, Ida Holmberg, Tobias Pamminger, Silvio
Erler, and Sylvia Cremer. “Social Environment Affects the Transcriptomic Response
to Bacteria in Ant Queens.” Ecology and Evolution. Wiley, 2018. https://doi.org/10.1002/ece3.4573.
ieee: L. Viljakainen, J. Jurvansuu, I. Holmberg, T. Pamminger, S. Erler, and S.
Cremer, “Social environment affects the transcriptomic response to bacteria in
ant queens,” Ecology and Evolution, vol. 8, no. 22. Wiley, pp. 11031–11070,
2018.
ista: Viljakainen L, Jurvansuu J, Holmberg I, Pamminger T, Erler S, Cremer S. 2018.
Social environment affects the transcriptomic response to bacteria in ant queens.
Ecology and Evolution. 8(22), 11031–11070.
mla: Viljakainen, Lumi, et al. “Social Environment Affects the Transcriptomic Response
to Bacteria in Ant Queens.” Ecology and Evolution, vol. 8, no. 22, Wiley,
2018, pp. 11031–70, doi:10.1002/ece3.4573.
short: L. Viljakainen, J. Jurvansuu, I. Holmberg, T. Pamminger, S. Erler, S. Cremer,
Ecology and Evolution 8 (2018) 11031–11070.
date_created: 2018-12-11T11:44:15Z
date_published: 2018-11-01T00:00:00Z
date_updated: 2023-09-19T09:29:12Z
day: '01'
ddc:
- '576'
- '591'
department:
- _id: SyCr
doi: 10.1002/ece3.4573
external_id:
isi:
- '000451611000032'
file:
- access_level: open_access
checksum: 0d1355c78627ca7210aadd9a17a01915
content_type: application/pdf
creator: dernst
date_created: 2018-12-17T08:27:04Z
date_updated: 2020-07-14T12:45:52Z
file_id: '5682'
file_name: Viljakainen_et_al-2018-Ecology_and_Evolution.pdf
file_size: 1272096
relation: main_file
file_date_updated: 2020-07-14T12:45:52Z
has_accepted_license: '1'
intvolume: ' 8'
isi: 1
issue: '22'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
page: 11031-11070
publication: Ecology and Evolution
publication_identifier:
issn:
- '20457758'
publication_status: published
publisher: Wiley
publist_id: '8026'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Social environment affects the transcriptomic response to bacteria in ant queens
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 8
year: '2018'
...
---
_id: '291'
abstract:
- lang: eng
text: Over the past decade, the edge of chaos has proven to be a fruitful starting
point for investigations of shear flows when the laminar base flow is linearly
stable. Numerous computational studies of shear flows demonstrated the existence
of states that separate laminar and turbulent regions of the state space. In addition,
some studies determined invariant solutions that reside on this edge. In this
paper, we study the unstable manifold of one such solution with the aid of continuous
symmetry reduction, which we formulate here for the simultaneous quotiening of
axial and azimuthal symmetries. Upon our investigation of the unstable manifold,
we discover a previously unknown traveling-wave solution on the laminar-turbulent
boundary with a relatively complex structure. By means of low-dimensional projections,
we visualize different dynamical paths that connect these solutions to the turbulence.
Our numerical experiments demonstrate that the laminar-turbulent boundary exhibits
qualitatively different regions whose properties are influenced by the nearby
invariant solutions.
article_number: '054401'
article_processing_charge: No
arxiv: 1
author:
- first_name: Nazmi B
full_name: Budanur, Nazmi B
id: 3EA1010E-F248-11E8-B48F-1D18A9856A87
last_name: Budanur
orcid: 0000-0003-0423-5010
- first_name: Björn
full_name: Hof, Björn
id: 3A374330-F248-11E8-B48F-1D18A9856A87
last_name: Hof
orcid: 0000-0003-2057-2754
citation:
ama: Budanur NB, Hof B. Complexity of the laminar-turbulent boundary in pipe flow.
Physical Review Fluids. 2018;3(5). doi:10.1103/PhysRevFluids.3.054401
apa: Budanur, N. B., & Hof, B. (2018). Complexity of the laminar-turbulent boundary
in pipe flow. Physical Review Fluids. American Physical Society. https://doi.org/10.1103/PhysRevFluids.3.054401
chicago: Budanur, Nazmi B, and Björn Hof. “Complexity of the Laminar-Turbulent Boundary
in Pipe Flow.” Physical Review Fluids. American Physical Society, 2018.
https://doi.org/10.1103/PhysRevFluids.3.054401.
ieee: N. B. Budanur and B. Hof, “Complexity of the laminar-turbulent boundary in
pipe flow,” Physical Review Fluids, vol. 3, no. 5. American Physical Society,
2018.
ista: Budanur NB, Hof B. 2018. Complexity of the laminar-turbulent boundary in pipe
flow. Physical Review Fluids. 3(5), 054401.
mla: Budanur, Nazmi B., and Björn Hof. “Complexity of the Laminar-Turbulent Boundary
in Pipe Flow.” Physical Review Fluids, vol. 3, no. 5, 054401, American
Physical Society, 2018, doi:10.1103/PhysRevFluids.3.054401.
short: N.B. Budanur, B. Hof, Physical Review Fluids 3 (2018).
date_created: 2018-12-11T11:45:39Z
date_published: 2018-05-30T00:00:00Z
date_updated: 2023-09-11T12:45:44Z
day: '30'
department:
- _id: BjHo
doi: 10.1103/PhysRevFluids.3.054401
external_id:
arxiv:
- '1802.01918'
isi:
- '000433426200001'
intvolume: ' 3'
isi: 1
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1802.01918
month: '05'
oa: 1
oa_version: Preprint
publication: Physical Review Fluids
publication_status: published
publisher: American Physical Society
publist_id: '7590'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Complexity of the laminar-turbulent boundary in pipe flow
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 3
year: '2018'
...
---
_id: '292'
abstract:
- lang: eng
text: 'Retina is a paradigmatic system for studying sensory encoding: the transformation
of light into spiking activity of ganglion cells. The inverse problem, where stimulus
is reconstructed from spikes, has received less attention, especially for complex
stimuli that should be reconstructed “pixel-by-pixel”. We recorded around a hundred
neurons from a dense patch in a rat retina and decoded movies of multiple small
randomly-moving discs. We constructed nonlinear (kernelized and neural network)
decoders that improved significantly over linear results. An important contribution
to this was the ability of nonlinear decoders to reliably separate between neural
responses driven by locally fluctuating light signals, and responses at locally
constant light driven by spontaneous-like activity. This improvement crucially
depended on the precise, non-Poisson temporal structure of individual spike trains,
which originated in the spike-history dependence of neural responses. We propose
a general principle by which downstream circuitry could discriminate between spontaneous
and stimulus-driven activity based solely on higher-order statistical structure
in the incoming spike trains.'
article_number: e1006057
article_processing_charge: Yes
article_type: original
author:
- first_name: Vicent
full_name: Botella Soler, Vicent
id: 421234E8-F248-11E8-B48F-1D18A9856A87
last_name: Botella Soler
orcid: 0000-0002-8790-1914
- first_name: Stephane
full_name: Deny, Stephane
last_name: Deny
- first_name: Georg S
full_name: Martius, Georg S
last_name: Martius
- first_name: Olivier
full_name: Marre, Olivier
last_name: Marre
- first_name: Gasper
full_name: Tkacik, Gasper
id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
last_name: Tkacik
orcid: 0000-0002-6699-1455
citation:
ama: Botella Soler V, Deny S, Martius GS, Marre O, Tkačik G. Nonlinear decoding
of a complex movie from the mammalian retina. PLoS Computational Biology.
2018;14(5). doi:10.1371/journal.pcbi.1006057
apa: Botella Soler, V., Deny, S., Martius, G. S., Marre, O., & Tkačik, G. (2018).
Nonlinear decoding of a complex movie from the mammalian retina. PLoS Computational
Biology. Public Library of Science. https://doi.org/10.1371/journal.pcbi.1006057
chicago: Botella Soler, Vicente, Stephane Deny, Georg S Martius, Olivier Marre,
and Gašper Tkačik. “Nonlinear Decoding of a Complex Movie from the Mammalian Retina.”
PLoS Computational Biology. Public Library of Science, 2018. https://doi.org/10.1371/journal.pcbi.1006057.
ieee: V. Botella Soler, S. Deny, G. S. Martius, O. Marre, and G. Tkačik, “Nonlinear
decoding of a complex movie from the mammalian retina,” PLoS Computational
Biology, vol. 14, no. 5. Public Library of Science, 2018.
ista: Botella Soler V, Deny S, Martius GS, Marre O, Tkačik G. 2018. Nonlinear decoding
of a complex movie from the mammalian retina. PLoS Computational Biology. 14(5),
e1006057.
mla: Botella Soler, Vicente, et al. “Nonlinear Decoding of a Complex Movie from
the Mammalian Retina.” PLoS Computational Biology, vol. 14, no. 5, e1006057,
Public Library of Science, 2018, doi:10.1371/journal.pcbi.1006057.
short: V. Botella Soler, S. Deny, G.S. Martius, O. Marre, G. Tkačik, PLoS Computational
Biology 14 (2018).
date_created: 2018-12-11T11:45:39Z
date_published: 2018-05-10T00:00:00Z
date_updated: 2024-02-21T13:45:25Z
day: '10'
ddc:
- '570'
department:
- _id: GaTk
doi: 10.1371/journal.pcbi.1006057
ec_funded: 1
external_id:
isi:
- '000434012100002'
file:
- access_level: open_access
checksum: 3026f94d235219e15514505fdbadf34e
content_type: application/pdf
creator: dernst
date_created: 2019-02-13T11:07:15Z
date_updated: 2020-07-14T12:45:53Z
file_id: '5974'
file_name: 2018_Plos_Botella_Soler.pdf
file_size: 3460786
relation: main_file
file_date_updated: 2020-07-14T12:45:53Z
has_accepted_license: '1'
intvolume: ' 14'
isi: 1
issue: '5'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
project:
- _id: 25CBA828-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '720270'
name: Human Brain Project Specific Grant Agreement 1 (HBP SGA 1)
- _id: 254D1A94-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 25651-N26
name: Sensitivity to higher-order statistics in natural scenes
publication: PLoS Computational Biology
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
related_material:
link:
- description: News on IST Homepage
relation: press_release
url: https://ist.ac.at/en/news/video-of-moving-discs-reconstructed-from-rat-retinal-neuron-signals/
record:
- id: '5584'
relation: research_data
status: public
scopus_import: '1'
status: public
title: Nonlinear decoding of a complex movie from the mammalian retina
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 14
year: '2018'
...
---
_id: '293'
abstract:
- lang: eng
text: People sometimes make their admirable deeds and accomplishments hard to spot,
such as by giving anonymously or avoiding bragging. Such ‘buried’ signals are
hard to reconcile with standard models of signalling or indirect reciprocity,
which motivate costly pro-social behaviour by reputational gains. To explain these
phenomena, we design a simple game theory model, which we call the signal-burying
game. This game has the feature that senders can bury their signal by deliberately
reducing the probability of the signal being observed. If the signal is observed,
however, it is identified as having been buried. We show under which conditions
buried signals can be maintained, using static equilibrium concepts and calculations
of the evolutionary dynamics. We apply our analysis to shed light on a number
of otherwise puzzling social phenomena, including modesty, anonymous donations,
subtlety in art and fashion, and overeagerness.
acknowledgement: This work was supported by a grant from the John Templeton Foundation
and by the Office of Naval Research Grant N00014-16-1-2914 (M.A.N.). C.H. acknowledges
generous support from the ISTFELLOW programme and by the Schrödinger scholarship
of the Austrian Science Fund (FWF) J3475.
article_processing_charge: No
article_type: original
author:
- first_name: Moshe
full_name: Hoffman, Moshe
last_name: Hoffman
- first_name: Christian
full_name: Hilbe, Christian
id: 2FDF8F3C-F248-11E8-B48F-1D18A9856A87
last_name: Hilbe
orcid: 0000-0001-5116-955X
- first_name: Martin
full_name: Nowak, Martin
last_name: Nowak
citation:
ama: Hoffman M, Hilbe C, Nowak M. The signal-burying game can explain why we obscure
positive traits and good deeds. Nature Human Behaviour. 2018;2:397-404.
doi:10.1038/s41562-018-0354-z
apa: Hoffman, M., Hilbe, C., & Nowak, M. (2018). The signal-burying game can
explain why we obscure positive traits and good deeds. Nature Human Behaviour.
Nature Publishing Group. https://doi.org/10.1038/s41562-018-0354-z
chicago: Hoffman, Moshe, Christian Hilbe, and Martin Nowak. “The Signal-Burying
Game Can Explain Why We Obscure Positive Traits and Good Deeds.” Nature Human
Behaviour. Nature Publishing Group, 2018. https://doi.org/10.1038/s41562-018-0354-z.
ieee: M. Hoffman, C. Hilbe, and M. Nowak, “The signal-burying game can explain why
we obscure positive traits and good deeds,” Nature Human Behaviour, vol.
2. Nature Publishing Group, pp. 397–404, 2018.
ista: Hoffman M, Hilbe C, Nowak M. 2018. The signal-burying game can explain why
we obscure positive traits and good deeds. Nature Human Behaviour. 2, 397–404.
mla: Hoffman, Moshe, et al. “The Signal-Burying Game Can Explain Why We Obscure
Positive Traits and Good Deeds.” Nature Human Behaviour, vol. 2, Nature
Publishing Group, 2018, pp. 397–404, doi:10.1038/s41562-018-0354-z.
short: M. Hoffman, C. Hilbe, M. Nowak, Nature Human Behaviour 2 (2018) 397–404.
date_created: 2018-12-11T11:45:39Z
date_published: 2018-05-28T00:00:00Z
date_updated: 2023-09-19T10:12:03Z
day: '28'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.1038/s41562-018-0354-z
ec_funded: 1
external_id:
isi:
- '000435551300009'
file:
- access_level: open_access
checksum: 32efaf06a597495c184df91b3fbb19c0
content_type: application/pdf
creator: dernst
date_created: 2019-11-19T08:17:23Z
date_updated: 2020-07-14T12:45:54Z
file_id: '7051'
file_name: 2018_NatureHumanBeh_Hoffman.pdf
file_size: 194734
relation: main_file
file_date_updated: 2020-07-14T12:45:54Z
has_accepted_license: '1'
intvolume: ' 2'
isi: 1
language:
- iso: eng
month: '05'
oa: 1
oa_version: Submitted Version
page: 397 - 404
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: Nature Human Behaviour
publication_status: published
publisher: Nature Publishing Group
publist_id: '7588'
quality_controlled: '1'
related_material:
link:
- description: News on IST Homepage
relation: press_release
url: https://ist.ac.at/en/news/the-logic-of-modesty-why-it-pays-to-be-humble/
scopus_import: '1'
status: public
title: The signal-burying game can explain why we obscure positive traits and good
deeds
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 2
year: '2018'
...
---
_id: '294'
abstract:
- lang: eng
text: We developed a method to calculate two-photon processes in quantum mechanics
that replaces the infinite summation over the intermediate states by a perturbation
expansion. This latter consists of a series of commutators that involve position,
momentum, and Hamiltonian quantum operators. We analyzed several single- and many-particle
cases for which a closed-form solution to the perturbation expansion exists, as
well as more complicated cases for which a solution is found by convergence. Throughout
the article, Rayleigh and Raman scattering are taken as examples of two-photon
processes. The present method provides a clear distinction between the Thomson
scattering, regarded as classical scattering, and quantum contributions. Such
a distinction lets us derive general results concerning light scattering. Finally,
possible extensions to the developed formalism are discussed.
article_processing_charge: No
arxiv: 1
author:
- first_name: Filippo
full_name: Fratini, Filippo
last_name: Fratini
- first_name: Laleh
full_name: Safari, Laleh
id: 3C325E5E-F248-11E8-B48F-1D18A9856A87
last_name: Safari
- first_name: Pedro
full_name: Amaro, Pedro
last_name: Amaro
- first_name: José
full_name: Santos, José
last_name: Santos
citation:
ama: Fratini F, Safari L, Amaro P, Santos J. Two-photon processes based on quantum
commutators. Physical Review A - Atomic, Molecular, and Optical Physics.
2018;97(4). doi:10.1103/PhysRevA.97.043842
apa: Fratini, F., Safari, L., Amaro, P., & Santos, J. (2018). Two-photon processes
based on quantum commutators. Physical Review A - Atomic, Molecular, and Optical
Physics. American Physical Society. https://doi.org/10.1103/PhysRevA.97.043842
chicago: Fratini, Filippo, Laleh Safari, Pedro Amaro, and José Santos. “Two-Photon
Processes Based on Quantum Commutators.” Physical Review A - Atomic, Molecular,
and Optical Physics. American Physical Society, 2018. https://doi.org/10.1103/PhysRevA.97.043842.
ieee: F. Fratini, L. Safari, P. Amaro, and J. Santos, “Two-photon processes based
on quantum commutators,” Physical Review A - Atomic, Molecular, and Optical
Physics, vol. 97, no. 4. American Physical Society, 2018.
ista: Fratini F, Safari L, Amaro P, Santos J. 2018. Two-photon processes based on
quantum commutators. Physical Review A - Atomic, Molecular, and Optical Physics.
97(4).
mla: Fratini, Filippo, et al. “Two-Photon Processes Based on Quantum Commutators.”
Physical Review A - Atomic, Molecular, and Optical Physics, vol. 97, no.
4, American Physical Society, 2018, doi:10.1103/PhysRevA.97.043842.
short: F. Fratini, L. Safari, P. Amaro, J. Santos, Physical Review A - Atomic, Molecular,
and Optical Physics 97 (2018).
date_created: 2018-12-11T11:45:40Z
date_published: 2018-04-18T00:00:00Z
date_updated: 2023-09-19T10:17:56Z
day: '18'
department:
- _id: MiLe
doi: 10.1103/PhysRevA.97.043842
ec_funded: 1
external_id:
arxiv:
- '1801.06892'
isi:
- '000430296800008'
intvolume: ' 97'
isi: 1
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1801.06892
month: '04'
oa: 1
oa_version: Submitted Version
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: Physical Review A - Atomic, Molecular, and Optical Physics
publication_status: published
publisher: American Physical Society
publist_id: '7587'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Two-photon processes based on quantum commutators
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 97
year: '2018'
...
---
_id: '295'
abstract:
- lang: eng
text: We prove upper and lower bounds on the ground-state energy of the ideal two-dimensional
anyon gas. Our bounds are extensive in the particle number, as for fermions, and
linear in the statistics parameter (Formula presented.). The lower bounds extend
to Lieb–Thirring inequalities for all anyons except bosons.
acknowledgement: Financial support from the Swedish Research Council, grant no. 2013-4734
(D. L.), the European Research Council (ERC) under the European Union’s Horizon
2020 research and innovation programme (grant agreement No 694227, R. S.), and by
the Austrian Science Fund (FWF), project Nr. P 27533-N27 (R. S.), is gratefully
acknowledged.
article_processing_charge: No
arxiv: 1
author:
- first_name: Douglas
full_name: Lundholm, Douglas
last_name: Lundholm
- first_name: Robert
full_name: Seiringer, Robert
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
citation:
ama: Lundholm D, Seiringer R. Fermionic behavior of ideal anyons. Letters in
Mathematical Physics. 2018;108(11):2523-2541. doi:10.1007/s11005-018-1091-y
apa: Lundholm, D., & Seiringer, R. (2018). Fermionic behavior of ideal anyons.
Letters in Mathematical Physics. Springer. https://doi.org/10.1007/s11005-018-1091-y
chicago: Lundholm, Douglas, and Robert Seiringer. “Fermionic Behavior of Ideal Anyons.”
Letters in Mathematical Physics. Springer, 2018. https://doi.org/10.1007/s11005-018-1091-y.
ieee: D. Lundholm and R. Seiringer, “Fermionic behavior of ideal anyons,” Letters
in Mathematical Physics, vol. 108, no. 11. Springer, pp. 2523–2541, 2018.
ista: Lundholm D, Seiringer R. 2018. Fermionic behavior of ideal anyons. Letters
in Mathematical Physics. 108(11), 2523–2541.
mla: Lundholm, Douglas, and Robert Seiringer. “Fermionic Behavior of Ideal Anyons.”
Letters in Mathematical Physics, vol. 108, no. 11, Springer, 2018, pp.
2523–41, doi:10.1007/s11005-018-1091-y.
short: D. Lundholm, R. Seiringer, Letters in Mathematical Physics 108 (2018) 2523–2541.
date_created: 2018-12-11T11:45:40Z
date_published: 2018-05-11T00:00:00Z
date_updated: 2023-09-11T14:01:57Z
day: '11'
ddc:
- '510'
department:
- _id: RoSe
doi: 10.1007/s11005-018-1091-y
ec_funded: 1
external_id:
arxiv:
- '1712.06218'
isi:
- '000446491500008'
file:
- access_level: open_access
checksum: 8beb9632fa41bbd19452f55f31286a31
content_type: application/pdf
creator: dernst
date_created: 2018-12-17T12:14:17Z
date_updated: 2020-07-14T12:45:55Z
file_id: '5698'
file_name: 2018_LettMathPhys_Lundholm.pdf
file_size: 551996
relation: main_file
file_date_updated: 2020-07-14T12:45:55Z
has_accepted_license: '1'
intvolume: ' 108'
isi: 1
issue: '11'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: 2523-2541
project:
- _id: 25C6DC12-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '694227'
name: Analysis of quantum many-body systems
- _id: 25C878CE-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P27533_N27
name: Structure of the Excitation Spectrum for Many-Body Quantum Systems
publication: Letters in Mathematical Physics
publication_status: published
publisher: Springer
publist_id: '7586'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Fermionic behavior of ideal anyons
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 108
year: '2018'
...
---
_id: '296'
abstract:
- lang: eng
text: The thermodynamic description of many-particle systems rests on the assumption
of ergodicity, the ability of a system to explore all allowed configurations in
the phase space. Recent studies on many-body localization have revealed the existence
of systems that strongly violate ergodicity in the presence of quenched disorder.
Here, we demonstrate that ergodicity can be weakly broken by a different mechanism,
arising from the presence of special eigenstates in the many-body spectrum that
are reminiscent of quantum scars in chaotic non-interacting systems. In the single-particle
case, quantum scars correspond to wavefunctions that concentrate in the vicinity
of unstable periodic classical trajectories. We show that many-body scars appear
in the Fibonacci chain, a model with a constrained local Hilbert space that has
recently been experimentally realized in a Rydberg-atom quantum simulator. The
quantum scarred eigenstates are embedded throughout the otherwise thermalizing
many-body spectrum but lead to direct experimental signatures, as we show for
periodic recurrences that reproduce those observed in the experiment. Our results
suggest that scarred many-body bands give rise to a new universality class of
quantum dynamics, opening up opportunities for the creation of novel states with
long-lived coherence in systems that are now experimentally realizable.
acknowledgement: C.J.T., A.M. and Z.P. acknowledge support from EPSRC grants EP/P009409/1
and EP/M50807X/1, and Royal Society Research Grant RG160635. D.A. acknowledges support
from the Swiss National Science Foundation.
article_processing_charge: No
article_type: original
author:
- first_name: Christopher
full_name: Turner, Christopher
last_name: Turner
- first_name: Alexios
full_name: Michailidis, Alexios
id: 36EBAD38-F248-11E8-B48F-1D18A9856A87
last_name: Michailidis
orcid: 0000-0002-8443-1064
- first_name: Dmitry
full_name: Abanin, Dmitry
last_name: Abanin
- first_name: Maksym
full_name: Serbyn, Maksym
id: 47809E7E-F248-11E8-B48F-1D18A9856A87
last_name: Serbyn
orcid: 0000-0002-2399-5827
- first_name: Zlatko
full_name: Papić, Zlatko
last_name: Papić
citation:
ama: Turner C, Michailidis A, Abanin D, Serbyn M, Papić Z. Weak ergodicity breaking
from quantum many-body scars. Nature Physics. 2018;14:745-749. doi:10.1038/s41567-018-0137-5
apa: Turner, C., Michailidis, A., Abanin, D., Serbyn, M., & Papić, Z. (2018).
Weak ergodicity breaking from quantum many-body scars. Nature Physics.
Nature Publishing Group. https://doi.org/10.1038/s41567-018-0137-5
chicago: Turner, Christopher, Alexios Michailidis, Dmitry Abanin, Maksym Serbyn,
and Zlatko Papić. “Weak Ergodicity Breaking from Quantum Many-Body Scars.” Nature
Physics. Nature Publishing Group, 2018. https://doi.org/10.1038/s41567-018-0137-5.
ieee: C. Turner, A. Michailidis, D. Abanin, M. Serbyn, and Z. Papić, “Weak ergodicity
breaking from quantum many-body scars,” Nature Physics, vol. 14. Nature
Publishing Group, pp. 745–749, 2018.
ista: Turner C, Michailidis A, Abanin D, Serbyn M, Papić Z. 2018. Weak ergodicity
breaking from quantum many-body scars. Nature Physics. 14, 745–749.
mla: Turner, Christopher, et al. “Weak Ergodicity Breaking from Quantum Many-Body
Scars.” Nature Physics, vol. 14, Nature Publishing Group, 2018, pp. 745–49,
doi:10.1038/s41567-018-0137-5.
short: C. Turner, A. Michailidis, D. Abanin, M. Serbyn, Z. Papić, Nature Physics
14 (2018) 745–749.
date_created: 2018-12-11T11:45:40Z
date_published: 2018-05-14T00:00:00Z
date_updated: 2023-09-19T10:37:55Z
day: '14'
department:
- _id: MaSe
doi: 10.1038/s41567-018-0137-5
external_id:
isi:
- '000438253600028'
intvolume: ' 14'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://eprints.whiterose.ac.uk/130860/
month: '05'
oa: 1
oa_version: Submitted Version
page: 745 - 749
publication: Nature Physics
publication_status: published
publisher: Nature Publishing Group
publist_id: '7585'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Weak ergodicity breaking from quantum many-body scars
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 14
year: '2018'
...
---
_id: '297'
abstract:
- lang: eng
text: Graph games played by two players over finite-state graphs are central in
many problems in computer science. In particular, graph games with ω -regular
winning conditions, specified as parity objectives, which can express properties
such as safety, liveness, fairness, are the basic framework for verification and
synthesis of reactive systems. The decisions for a player at various states of
the graph game are represented as strategies. While the algorithmic problem for
solving graph games with parity objectives has been widely studied, the most prominent
data-structure for strategy representation in graph games has been binary decision
diagrams (BDDs). However, due to the bit-level representation, BDDs do not retain
the inherent flavor of the decisions of strategies, and are notoriously hard to
minimize to obtain succinct representation. In this work we propose decision trees
for strategy representation in graph games. Decision trees retain the flavor of
decisions of strategies and allow entropy-based minimization to obtain succinct
trees. However, decision trees work in settings (e.g., probabilistic models) where
errors are allowed, and overfitting of data is typically avoided. In contrast,
for strategies in graph games no error is allowed, and the decision tree must
represent the entire strategy. We develop new techniques to extend decision trees
to overcome the above obstacles, while retaining the entropy-based techniques
to obtain succinct trees. We have implemented our techniques to extend the existing
decision tree solvers. We present experimental results for problems in reactive
synthesis to show that decision trees provide a much more efficient data-structure
for strategy representation as compared to BDDs.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Tomáš
full_name: Brázdil, Tomáš
last_name: Brázdil
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Jan
full_name: Kretinsky, Jan
id: 44CEF464-F248-11E8-B48F-1D18A9856A87
last_name: Kretinsky
orcid: 0000-0002-8122-2881
- first_name: Viktor
full_name: Toman, Viktor
id: 3AF3DA7C-F248-11E8-B48F-1D18A9856A87
last_name: Toman
orcid: 0000-0001-9036-063X
citation:
ama: 'Brázdil T, Chatterjee K, Kretinsky J, Toman V. Strategy representation by
decision trees in reactive synthesis. In: Vol 10805. Springer; 2018:385-407. doi:10.1007/978-3-319-89960-2_21'
apa: 'Brázdil, T., Chatterjee, K., Kretinsky, J., & Toman, V. (2018). Strategy
representation by decision trees in reactive synthesis (Vol. 10805, pp. 385–407).
Presented at the TACAS 2018: Tools and Algorithms for the Construction and Analysis
of Systems, Thessaloniki, Greece: Springer. https://doi.org/10.1007/978-3-319-89960-2_21'
chicago: Brázdil, Tomáš, Krishnendu Chatterjee, Jan Kretinsky, and Viktor Toman.
“Strategy Representation by Decision Trees in Reactive Synthesis,” 10805:385–407.
Springer, 2018. https://doi.org/10.1007/978-3-319-89960-2_21.
ieee: 'T. Brázdil, K. Chatterjee, J. Kretinsky, and V. Toman, “Strategy representation
by decision trees in reactive synthesis,” presented at the TACAS 2018: Tools and
Algorithms for the Construction and Analysis of Systems, Thessaloniki, Greece,
2018, vol. 10805, pp. 385–407.'
ista: 'Brázdil T, Chatterjee K, Kretinsky J, Toman V. 2018. Strategy representation
by decision trees in reactive synthesis. TACAS 2018: Tools and Algorithms for
the Construction and Analysis of Systems, LNCS, vol. 10805, 385–407.'
mla: Brázdil, Tomáš, et al. Strategy Representation by Decision Trees in Reactive
Synthesis. Vol. 10805, Springer, 2018, pp. 385–407, doi:10.1007/978-3-319-89960-2_21.
short: T. Brázdil, K. Chatterjee, J. Kretinsky, V. Toman, in:, Springer, 2018, pp.
385–407.
conference:
end_date: 2018-04-20
location: Thessaloniki, Greece
name: 'TACAS 2018: Tools and Algorithms for the Construction and Analysis of Systems'
start_date: 2018-04-14
date_created: 2018-12-11T11:45:41Z
date_published: 2018-04-12T00:00:00Z
date_updated: 2025-06-02T08:53:40Z
day: '12'
ddc:
- '000'
department:
- _id: KrCh
- _id: ToHe
doi: 10.1007/978-3-319-89960-2_21
ec_funded: 1
external_id:
isi:
- '000546326300021'
file:
- access_level: open_access
checksum: b13874ffb114932ad9cc2586b7469db4
content_type: application/pdf
creator: dernst
date_created: 2018-12-17T16:29:08Z
date_updated: 2020-07-14T12:45:57Z
file_id: '5723'
file_name: 2018_LNCS_Brazdil.pdf
file_size: 1829940
relation: main_file
file_date_updated: 2020-07-14T12:45:57Z
has_accepted_license: '1'
intvolume: ' 10805'
isi: 1
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 385 - 407
project:
- _id: 25892FC0-B435-11E9-9278-68D0E5697425
grant_number: ICT15-003
name: Efficient Algorithms for Computer Aided Verification
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '665385'
name: International IST Doctoral Program
publication_status: published
publisher: Springer
publist_id: '7584'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Strategy representation by decision trees in reactive synthesis
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 10805
year: '2018'
...