---
_id: '6888'
abstract:
- lang: eng
text: In this paper, we design novel liquid time-constant recurrent neural networks
for robotic control, inspired by the brain of the nematode, C. elegans. In the
worm's nervous system, neurons communicate through nonlinear time-varying synaptic
links established amongst them by their particular wiring structure. This property
enables neurons to express liquid time-constants dynamics and therefore allows
the network to originate complex behaviors with a small number of neurons. We
identify neuron-pair communication motifs as design operators and use them to
configure compact neuronal network structures to govern sequential robotic tasks.
The networks are systematically designed to map the environmental observations
to motor actions, by their hierarchical topology from sensory neurons, through
recurrently-wired interneurons, to motor neurons. The networks are then parametrized
in a supervised-learning scheme by a search-based algorithm. We demonstrate that
obtained networks realize interpretable dynamics. We evaluate their performance
in controlling mobile and arm robots, and compare their attributes to other artificial
neural network-based control agents. Finally, we experimentally show their superior
resilience to environmental noise, compared to the existing machine learning-based
methods.
alternative_title:
- ICRA
article_number: '8793840'
article_processing_charge: No
author:
- first_name: Mathias
full_name: Lechner, Mathias
id: 3DC22916-F248-11E8-B48F-1D18A9856A87
last_name: Lechner
- first_name: Ramin
full_name: Hasani, Ramin
last_name: Hasani
- first_name: Manuel
full_name: Zimmer, Manuel
last_name: Zimmer
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Radu
full_name: Grosu, Radu
last_name: Grosu
citation:
ama: 'Lechner M, Hasani R, Zimmer M, Henzinger TA, Grosu R. Designing worm-inspired
neural networks for interpretable robotic control. In: Proceedings - IEEE International
Conference on Robotics and Automation. Vol 2019-May. IEEE; 2019. doi:10.1109/icra.2019.8793840'
apa: 'Lechner, M., Hasani, R., Zimmer, M., Henzinger, T. A., & Grosu, R. (2019).
Designing worm-inspired neural networks for interpretable robotic control. In
Proceedings - IEEE International Conference on Robotics and Automation
(Vol. 2019–May). Montreal, QC, Canada: IEEE. https://doi.org/10.1109/icra.2019.8793840'
chicago: Lechner, Mathias, Ramin Hasani, Manuel Zimmer, Thomas A Henzinger, and
Radu Grosu. “Designing Worm-Inspired Neural Networks for Interpretable Robotic
Control.” In Proceedings - IEEE International Conference on Robotics and Automation,
Vol. 2019–May. IEEE, 2019. https://doi.org/10.1109/icra.2019.8793840.
ieee: M. Lechner, R. Hasani, M. Zimmer, T. A. Henzinger, and R. Grosu, “Designing
worm-inspired neural networks for interpretable robotic control,” in Proceedings
- IEEE International Conference on Robotics and Automation, Montreal, QC,
Canada, 2019, vol. 2019–May.
ista: 'Lechner M, Hasani R, Zimmer M, Henzinger TA, Grosu R. 2019. Designing worm-inspired
neural networks for interpretable robotic control. Proceedings - IEEE International
Conference on Robotics and Automation. ICRA: International Conference on Robotics
and Automation, ICRA, vol. 2019–May, 8793840.'
mla: Lechner, Mathias, et al. “Designing Worm-Inspired Neural Networks for Interpretable
Robotic Control.” Proceedings - IEEE International Conference on Robotics and
Automation, vol. 2019–May, 8793840, IEEE, 2019, doi:10.1109/icra.2019.8793840.
short: M. Lechner, R. Hasani, M. Zimmer, T.A. Henzinger, R. Grosu, in:, Proceedings
- IEEE International Conference on Robotics and Automation, IEEE, 2019.
conference:
end_date: 2019-05-24
location: Montreal, QC, Canada
name: 'ICRA: International Conference on Robotics and Automation'
start_date: 2019-05-20
date_created: 2019-09-18T08:09:51Z
date_published: 2019-05-01T00:00:00Z
date_updated: 2021-01-12T08:09:28Z
day: '01'
ddc:
- '000'
department:
- _id: ToHe
doi: 10.1109/icra.2019.8793840
file:
- access_level: open_access
checksum: f5545a6b60c3ffd01feb3613f81d03b6
content_type: application/pdf
creator: dernst
date_created: 2020-10-08T17:30:38Z
date_updated: 2020-10-08T17:30:38Z
file_id: '8636'
file_name: 2019_ICRA_Lechner.pdf
file_size: 3265107
relation: main_file
success: 1
file_date_updated: 2020-10-08T17:30:38Z
has_accepted_license: '1'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Submitted Version
project:
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z211
name: The Wittgenstein Prize
publication: Proceedings - IEEE International Conference on Robotics and Automation
publication_identifier:
isbn:
- '9781538660270'
publication_status: published
publisher: IEEE
quality_controlled: '1'
scopus_import: '1'
status: public
title: Designing worm-inspired neural networks for interpretable robotic control
type: conference
user_id: D865714E-FA4E-11E9-B85B-F5C5E5697425
volume: 2019-May
year: '2019'
...
---
_id: '6889'
abstract:
- lang: eng
text: 'We study Markov decision processes and turn-based stochastic games with parity
conditions. There are three qualitative winning criteria, namely, sure winning,
which requires all paths to satisfy the condition, almost-sure winning, which
requires the condition to be satisfied with probability 1, and limit-sure winning,
which requires the condition to be satisfied with probability arbitrarily close
to 1. We study the combination of two of these criteria for parity conditions,
e.g., there are two parity conditions one of which must be won surely, and the
other almost-surely. The problem has been studied recently by Berthon et al. for
MDPs with combination of sure and almost-sure winning, under infinite-memory strategies,
and the problem has been established to be in NP cap co-NP. Even in MDPs there
is a difference between finite-memory and infinite-memory strategies. Our main
results for combination of sure and almost-sure winning are as follows: (a) we
show that for MDPs with finite-memory strategies the problem is in NP cap co-NP;
(b) we show that for turn-based stochastic games the problem is co-NP-complete,
both for finite-memory and infinite-memory strategies; and (c) we present algorithmic
results for the finite-memory case, both for MDPs and turn-based stochastic games,
by reduction to non-stochastic parity games. In addition we show that all the
above complexity results also carry over to combination of sure and limit-sure
winning, and results for all other combinations can be derived from existing results
in the literature. Thus we present a complete picture for the study of combinations
of two qualitative winning criteria for parity conditions in MDPs and turn-based
stochastic games. '
alternative_title:
- LIPIcs
article_number: '6'
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Nir
full_name: Piterman, Nir
last_name: Piterman
citation:
ama: 'Chatterjee K, Piterman N. Combinations of Qualitative Winning for Stochastic
Parity Games. In: Vol 140. Schloss Dagstuhl - Leibniz-Zentrum für Informatik;
2019. doi:10.4230/LIPICS.CONCUR.2019.6'
apa: 'Chatterjee, K., & Piterman, N. (2019). Combinations of Qualitative Winning
for Stochastic Parity Games (Vol. 140). Presented at the CONCUR: International
Conference on Concurrency Theory, Amsterdam, Netherlands: Schloss Dagstuhl - Leibniz-Zentrum
für Informatik. https://doi.org/10.4230/LIPICS.CONCUR.2019.6'
chicago: Chatterjee, Krishnendu, and Nir Piterman. “Combinations of Qualitative
Winning for Stochastic Parity Games,” Vol. 140. Schloss Dagstuhl - Leibniz-Zentrum
für Informatik, 2019. https://doi.org/10.4230/LIPICS.CONCUR.2019.6.
ieee: 'K. Chatterjee and N. Piterman, “Combinations of Qualitative Winning for Stochastic
Parity Games,” presented at the CONCUR: International Conference on Concurrency
Theory, Amsterdam, Netherlands, 2019, vol. 140.'
ista: 'Chatterjee K, Piterman N. 2019. Combinations of Qualitative Winning for Stochastic
Parity Games. CONCUR: International Conference on Concurrency Theory, LIPIcs,
vol. 140, 6.'
mla: Chatterjee, Krishnendu, and Nir Piterman. Combinations of Qualitative Winning
for Stochastic Parity Games. Vol. 140, 6, Schloss Dagstuhl - Leibniz-Zentrum
für Informatik, 2019, doi:10.4230/LIPICS.CONCUR.2019.6.
short: K. Chatterjee, N. Piterman, in:, Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
2019.
conference:
end_date: 2019-08-30
location: Amsterdam, Netherlands
name: 'CONCUR: International Conference on Concurrency Theory'
start_date: 2019-08-27
date_created: 2019-09-18T08:11:43Z
date_published: 2019-08-01T00:00:00Z
date_updated: 2021-01-12T08:09:28Z
day: '01'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.4230/LIPICS.CONCUR.2019.6
file:
- access_level: open_access
checksum: 7b2ecfd4d9d02360308c0ca986fc10a7
content_type: application/pdf
creator: kschuh
date_created: 2019-10-01T08:49:45Z
date_updated: 2020-07-14T12:47:43Z
file_id: '6923'
file_name: 2019_LIPIcs_Chatterjee.pdf
file_size: 509163
relation: main_file
file_date_updated: 2020-07-14T12:47:43Z
has_accepted_license: '1'
intvolume: ' 140'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
project:
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11407
name: Game Theory
- _id: 25892FC0-B435-11E9-9278-68D0E5697425
grant_number: ICT15-003
name: Efficient Algorithms for Computer Aided Verification
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
quality_controlled: '1'
scopus_import: 1
status: public
title: Combinations of Qualitative Winning for Stochastic Parity Games
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 140
year: '2019'
...
---
_id: '6890'
abstract:
- lang: eng
text: Describing the protein interactions that form pleomorphic and asymmetric viruses
represents a considerable challenge to most structural biology techniques, including
X-ray crystallography and single particle cryo-electron microscopy. Obtaining
a detailed understanding of these interactions is nevertheless important, considering
the number of relevant human pathogens that do not follow strict icosahedral or
helical symmetry. Cryo-electron tomography and subtomogram averaging methods provide
structural insights into complex biological environments and are well suited to
go beyond structures of perfectly symmetric viruses. This chapter discusses recent
developments showing that cryo-ET and subtomogram averaging can provide high-resolution
insights into hitherto unknown structural features of pleomorphic and asymmetric
virus particles. It also describes how these methods have significantly added
to our understanding of retrovirus capsid assemblies in immature and mature viruses.
Additional examples of irregular viruses and their associated proteins, whose
structures have been studied via cryo-ET and subtomogram averaging, further support
the versatility of these methods.
article_processing_charge: No
author:
- first_name: Martin
full_name: Obr, Martin
id: 4741CA5A-F248-11E8-B48F-1D18A9856A87
last_name: Obr
orcid: 0000-0003-1756-6564
- first_name: Florian KM
full_name: Schur, Florian KM
id: 48AD8942-F248-11E8-B48F-1D18A9856A87
last_name: Schur
orcid: 0000-0003-4790-8078
citation:
ama: 'Obr M, Schur FK. Structural analysis of pleomorphic and asymmetric viruses
using cryo-electron tomography and subtomogram averaging. In: Rey FA, ed. Complementary
Strategies to Study Virus Structure and Function. Vol 105. Advances in Virus
Research. Elsevier; 2019:117-159. doi:10.1016/bs.aivir.2019.07.008'
apa: Obr, M., & Schur, F. K. (2019). Structural analysis of pleomorphic and
asymmetric viruses using cryo-electron tomography and subtomogram averaging. In
F. A. Rey (Ed.), Complementary Strategies to Study Virus Structure and Function
(Vol. 105, pp. 117–159). Elsevier. https://doi.org/10.1016/bs.aivir.2019.07.008
chicago: Obr, Martin, and Florian KM Schur. “Structural Analysis of Pleomorphic
and Asymmetric Viruses Using Cryo-Electron Tomography and Subtomogram Averaging.”
In Complementary Strategies to Study Virus Structure and Function, edited
by Félix A. Rey, 105:117–59. Advances in Virus Research. Elsevier, 2019. https://doi.org/10.1016/bs.aivir.2019.07.008.
ieee: M. Obr and F. K. Schur, “Structural analysis of pleomorphic and asymmetric
viruses using cryo-electron tomography and subtomogram averaging,” in Complementary
Strategies to Study Virus Structure and Function, vol. 105, F. A. Rey, Ed.
Elsevier, 2019, pp. 117–159.
ista: 'Obr M, Schur FK. 2019.Structural analysis of pleomorphic and asymmetric viruses
using cryo-electron tomography and subtomogram averaging. In: Complementary Strategies
to Study Virus Structure and Function. vol. 105, 117–159.'
mla: Obr, Martin, and Florian KM Schur. “Structural Analysis of Pleomorphic and
Asymmetric Viruses Using Cryo-Electron Tomography and Subtomogram Averaging.”
Complementary Strategies to Study Virus Structure and Function, edited
by Félix A. Rey, vol. 105, Elsevier, 2019, pp. 117–59, doi:10.1016/bs.aivir.2019.07.008.
short: M. Obr, F.K. Schur, in:, F.A. Rey (Ed.), Complementary Strategies to Study
Virus Structure and Function, Elsevier, 2019, pp. 117–159.
date_created: 2019-09-18T08:15:37Z
date_published: 2019-08-27T00:00:00Z
date_updated: 2023-08-30T06:56:00Z
day: '27'
department:
- _id: FlSc
doi: 10.1016/bs.aivir.2019.07.008
editor:
- first_name: Félix A.
full_name: Rey, Félix A.
last_name: Rey
external_id:
isi:
- '000501594500006'
pmid:
- ' 31522703'
intvolume: ' 105'
isi: 1
language:
- iso: eng
month: '08'
oa_version: None
page: 117-159
pmid: 1
publication: Complementary Strategies to Study Virus Structure and Function
publication_identifier:
isbn:
- '9780128184561'
issn:
- 0065-3527
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
series_title: Advances in Virus Research
status: public
title: Structural analysis of pleomorphic and asymmetric viruses using cryo-electron
tomography and subtomogram averaging
type: book_chapter
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 105
year: '2019'
...
---
_id: '6891'
abstract:
- lang: eng
text: "While cells of mesenchymal or epithelial origin perform their effector functions
in a purely anchorage dependent manner, cells derived from the hematopoietic lineage
are not committed to operate only within a specific niche. Instead, these cells
are able to function autonomously of the molecular composition in a broad range
of tissue compartments. By this means, cells of the hematopoietic lineage retain
the capacity to disseminate into connective tissue and recirculate between organs,
building the foundation for essential processes such as tissue regeneration or
immune surveillance. \r\nCells of the immune system, specifically leukocytes,
are extraordinarily good at performing this task. These cells are able to flexibly
shift their mode of migration between an adhesion-mediated and an adhesion-independent
manner, instantaneously accommodating for any changes in molecular composition
of the external scaffold. The key component driving directed leukocyte migration
is the chemokine receptor 7, which guides the cell along gradients of chemokine
ligand. Therefore, the physical destination of migrating leukocytes is purely
deterministic, i.e. given by global directional cues such as chemokine gradients.
\r\nNevertheless, these cells typically reside in three-dimensional scaffolds
of inhomogeneous complexity, raising the question whether cells are able to locally
discriminate between multiple optional migration routes. Current literature provides
evidence that leukocytes, specifically dendritic cells, do indeed probe their
surrounding by virtue of multiple explorative protrusions. However, it remains
enigmatic how these cells decide which one is the more favorable route to follow
and what are the key players involved in performing this task. Due to the heterogeneous
environment of most tissues, and the vast adaptability of migrating leukocytes,
at this time it is not clear to what extent leukocytes are able to optimize their
migratory strategy by adapting their level of adhesiveness. And, given the fact
that leukocyte migration is characterized by branched cell shapes in combination
with high migration velocities, it is reasonable to assume that these cells require
fine tuned shape maintenance mechanisms that tightly coordinate protrusion and
adhesion dynamics in a spatiotemporal manner. \r\nTherefore, this study aimed
to elucidate how rapidly migrating leukocytes opt for an ideal migratory path
while maintaining a continuous cell shape and balancing adhesive forces to efficiently
navigate through complex microenvironments. \r\nThe results of this study unraveled
a role for the microtubule cytoskeleton in promoting the decision making process
during path finding and for the first time point towards a microtubule-mediated
function in cell shape maintenance of highly ramified cells such as dendritic
cells. Furthermore, we found that migrating low-adhesive leukocytes are able to
instantaneously adapt to increased tensile load by engaging adhesion receptors.
This response was only occurring tangential to the substrate while adhesive properties
in the vertical direction were not increased. As leukocytes are primed for rapid
migration velocities, these results demonstrate that leukocyte integrins are able
to confer a high level of traction forces parallel to the cell membrane along
the direction of migration without wasting energy in gluing the cell to the substrate.
\r\nThus, the data in the here presented thesis provide new insights into the
pivotal role of cytoskeletal dynamics and the mechanisms of force transduction
during leukocyte migration. \r\nThereby the here presented results help to further
define fundamental principles underlying leukocyte migration and open up potential
therapeutic avenues of clinical relevance.\r\n"
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Aglaja
full_name: Kopf, Aglaja
id: 31DAC7B6-F248-11E8-B48F-1D18A9856A87
last_name: Kopf
orcid: 0000-0002-2187-6656
citation:
ama: Kopf A. The implication of cytoskeletal dynamics on leukocyte migration. 2019.
doi:10.15479/AT:ISTA:6891
apa: Kopf, A. (2019). The implication of cytoskeletal dynamics on leukocyte migration.
Institute of Science and Technology Austria. https://doi.org/10.15479/AT:ISTA:6891
chicago: Kopf, Aglaja. “The Implication of Cytoskeletal Dynamics on Leukocyte Migration.”
Institute of Science and Technology Austria, 2019. https://doi.org/10.15479/AT:ISTA:6891.
ieee: A. Kopf, “The implication of cytoskeletal dynamics on leukocyte migration,”
Institute of Science and Technology Austria, 2019.
ista: Kopf A. 2019. The implication of cytoskeletal dynamics on leukocyte migration.
Institute of Science and Technology Austria.
mla: Kopf, Aglaja. The Implication of Cytoskeletal Dynamics on Leukocyte Migration.
Institute of Science and Technology Austria, 2019, doi:10.15479/AT:ISTA:6891.
short: A. Kopf, The Implication of Cytoskeletal Dynamics on Leukocyte Migration,
Institute of Science and Technology Austria, 2019.
date_created: 2019-09-19T08:19:44Z
date_published: 2019-07-24T00:00:00Z
date_updated: 2023-10-18T08:49:17Z
day: '24'
ddc:
- '570'
degree_awarded: PhD
department:
- _id: MiSi
doi: 10.15479/AT:ISTA:6891
file:
- access_level: closed
checksum: 00d100d6468e31e583051e0a006b640c
content_type: application/vnd.openxmlformats-officedocument.wordprocessingml.document
creator: akopf
date_created: 2019-10-15T05:28:42Z
date_updated: 2020-10-17T22:30:03Z
embargo_to: open_access
file_id: '6950'
file_name: Kopf_PhD_Thesis.docx
file_size: 74735267
relation: source_file
- access_level: open_access
checksum: 5d1baa899993ae6ca81aebebe1797000
content_type: application/pdf
creator: akopf
date_created: 2019-10-15T05:28:47Z
date_updated: 2020-10-17T22:30:03Z
embargo: 2020-10-16
file_id: '6951'
file_name: Kopf_PhD_Thesis1.pdf
file_size: 52787224
relation: main_file
file_date_updated: 2020-10-17T22:30:03Z
has_accepted_license: '1'
keyword:
- cell biology
- immunology
- leukocyte
- migration
- microfluidics
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: '171'
project:
- _id: 265E2996-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: W01250-B20
name: Nano-Analytics of Cellular Systems
publication_identifier:
eissn:
- 2663-337X
isbn:
- 978-3-99078-002-2
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
link:
- relation: press_release
url: https://ist.ac.at/en/news/feeling-like-a-cell/
record:
- id: '6328'
relation: part_of_dissertation
status: public
- id: '15'
relation: part_of_dissertation
status: public
- id: '6877'
relation: part_of_dissertation
status: public
status: public
supervisor:
- first_name: Michael K
full_name: Sixt, Michael K
id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
last_name: Sixt
orcid: 0000-0002-6620-9179
title: The implication of cytoskeletal dynamics on leukocyte migration
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2019'
...
---
_id: '6894'
abstract:
- lang: eng
text: "Hybrid automata combine finite automata and dynamical systems, and model
the interaction of digital with physical systems. Formal analysis that can guarantee
the safety of all behaviors or rigorously witness failures, while unsolvable in
general, has been tackled algorithmically using, e.g., abstraction, bounded model-checking,
assisted theorem proving.\r\nNevertheless, very few methods have addressed the
time-unbounded reachability analysis of hybrid automata and, for current sound
and automatic tools, scalability remains critical. We develop methods for the
polyhedral abstraction of hybrid automata, which construct coarse overapproximations
and tightens them incrementally, in a CEGAR fashion. We use template polyhedra,
i.e., polyhedra whose facets are normal to a given set of directions.\r\nWhile,
previously, directions were given by the user, we introduce (1) the first method\r\nfor
computing template directions from spurious counterexamples, so as to generalize
and\r\neliminate them. The method applies naturally to convex hybrid automata,
i.e., hybrid\r\nautomata with (possibly non-linear) convex constraints on derivatives
only, while for linear\r\nODE requires further abstraction. Specifically, we introduce
(2) the conic abstractions,\r\nwhich, partitioning the state space into appropriate
(possibly non-uniform) cones, divide\r\ncurvy trajectories into relatively straight
sections, suitable for polyhedral abstractions.\r\nFinally, we introduce (3) space-time
interpolation, which, combining interval arithmetic\r\nand template refinement,
computes appropriate (possibly non-uniform) time partitioning\r\nand template
directions along spurious trajectories, so as to eliminate them.\r\nWe obtain
sound and automatic methods for the reachability analysis over dense\r\nand unbounded
time of convex hybrid automata and hybrid automata with linear ODE.\r\nWe build
prototype tools and compare—favorably—our methods against the respective\r\nstate-of-the-art
tools, on several benchmarks."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Mirco
full_name: Giacobbe, Mirco
id: 3444EA5E-F248-11E8-B48F-1D18A9856A87
last_name: Giacobbe
orcid: 0000-0001-8180-0904
citation:
ama: Giacobbe M. Automatic time-unbounded reachability analysis of hybrid systems.
2019. doi:10.15479/AT:ISTA:6894
apa: Giacobbe, M. (2019). Automatic time-unbounded reachability analysis of hybrid
systems. Institute of Science and Technology Austria. https://doi.org/10.15479/AT:ISTA:6894
chicago: Giacobbe, Mirco. “Automatic Time-Unbounded Reachability Analysis of Hybrid
Systems.” Institute of Science and Technology Austria, 2019. https://doi.org/10.15479/AT:ISTA:6894.
ieee: M. Giacobbe, “Automatic time-unbounded reachability analysis of hybrid systems,”
Institute of Science and Technology Austria, 2019.
ista: Giacobbe M. 2019. Automatic time-unbounded reachability analysis of hybrid
systems. Institute of Science and Technology Austria.
mla: Giacobbe, Mirco. Automatic Time-Unbounded Reachability Analysis of Hybrid
Systems. Institute of Science and Technology Austria, 2019, doi:10.15479/AT:ISTA:6894.
short: M. Giacobbe, Automatic Time-Unbounded Reachability Analysis of Hybrid Systems,
Institute of Science and Technology Austria, 2019.
date_created: 2019-09-22T14:08:44Z
date_published: 2019-09-30T00:00:00Z
date_updated: 2023-09-19T09:30:43Z
day: '30'
ddc:
- '000'
degree_awarded: PhD
department:
- _id: ToHe
doi: 10.15479/AT:ISTA:6894
file:
- access_level: open_access
checksum: 773beaf4a85dc2acc2c12b578fbe1965
content_type: application/pdf
creator: mgiacobbe
date_created: 2019-09-27T14:15:05Z
date_updated: 2020-07-14T12:47:43Z
file_id: '6916'
file_name: giacobbe_thesis.pdf
file_size: 4100685
relation: main_file
- access_level: closed
checksum: 97f1c3da71feefd27e6e625d32b4c75b
content_type: application/gzip
creator: mgiacobbe
date_created: 2019-09-27T14:22:04Z
date_updated: 2020-07-14T12:47:43Z
file_id: '6917'
file_name: giacobbe_thesis_src.tar.gz
file_size: 7959732
relation: source_file
file_date_updated: 2020-07-14T12:47:43Z
has_accepted_license: '1'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: '132'
publication_identifier:
eissn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
record:
- id: '631'
relation: part_of_dissertation
status: public
- id: '647'
relation: part_of_dissertation
status: public
- id: '140'
relation: part_of_dissertation
status: public
status: public
supervisor:
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
title: Automatic time-unbounded reachability analysis of hybrid systems
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2019'
...
---
_id: '6896'
abstract:
- lang: eng
text: "Until recently, a great amount of brain studies have been conducted in human
post mortem tissues, cell lines and model organisms. These researches provided
useful insights regarding cell-cell interactions occurring in the brain. However,
such approaches suffer from technical limitations and inaccurate modeling of the
tissue 3D cytoarchitecture. Importantly, they might lack a human genetic background
essential for disease modeling. With the development of protocols to generate
human cerebral organoids, we are now closer to reproducing the early stages of
human brain development in vitro. As a result, more relevant cell-cell interaction
studies can be conducted.\r\n\r\nIn this review, we discuss the advantages of
3D cultures over 2D in modulating brain cell-cell interactions during physiological
and pathological development, as well as the progress made in developing organoids
in which neurons, macroglia, microglia and vascularization are present. Finally,
we debate the limitations of those models and possible future directions."
article_number: '146458'
article_processing_charge: No
article_type: original
author:
- first_name: Bárbara
full_name: Oliveira, Bárbara
id: 3B03AA1A-F248-11E8-B48F-1D18A9856A87
last_name: Oliveira
- first_name: Aysan Çerağ
full_name: Yahya, Aysan Çerağ
id: 365A65F8-F248-11E8-B48F-1D18A9856A87
last_name: Yahya
- first_name: Gaia
full_name: Novarino, Gaia
id: 3E57A680-F248-11E8-B48F-1D18A9856A87
last_name: Novarino
orcid: 0000-0002-7673-7178
citation:
ama: Oliveira B, Yahya AÇ, Novarino G. Modeling cell-cell interactions in the brain
using cerebral organoids. Brain Research. 2019;1724. doi:10.1016/j.brainres.2019.146458
apa: Oliveira, B., Yahya, A. Ç., & Novarino, G. (2019). Modeling cell-cell interactions
in the brain using cerebral organoids. Brain Research. Elsevier. https://doi.org/10.1016/j.brainres.2019.146458
chicago: Oliveira, Bárbara, Aysan Çerağ Yahya, and Gaia Novarino. “Modeling Cell-Cell
Interactions in the Brain Using Cerebral Organoids.” Brain Research. Elsevier,
2019. https://doi.org/10.1016/j.brainres.2019.146458.
ieee: B. Oliveira, A. Ç. Yahya, and G. Novarino, “Modeling cell-cell interactions
in the brain using cerebral organoids,” Brain Research, vol. 1724. Elsevier,
2019.
ista: Oliveira B, Yahya AÇ, Novarino G. 2019. Modeling cell-cell interactions in
the brain using cerebral organoids. Brain Research. 1724, 146458.
mla: Oliveira, Bárbara, et al. “Modeling Cell-Cell Interactions in the Brain Using
Cerebral Organoids.” Brain Research, vol. 1724, 146458, Elsevier, 2019,
doi:10.1016/j.brainres.2019.146458.
short: B. Oliveira, A.Ç. Yahya, G. Novarino, Brain Research 1724 (2019).
date_created: 2019-09-22T22:00:35Z
date_published: 2019-12-01T00:00:00Z
date_updated: 2023-08-30T06:19:49Z
day: '01'
department:
- _id: GaNo
doi: 10.1016/j.brainres.2019.146458
external_id:
isi:
- '000491646600033'
pmid:
- '31521639'
intvolume: ' 1724'
isi: 1
language:
- iso: eng
month: '12'
oa_version: None
pmid: 1
publication: Brain Research
publication_identifier:
eissn:
- '18726240'
issn:
- '00068993'
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Modeling cell-cell interactions in the brain using cerebral organoids
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 1724
year: '2019'
...
---
_id: '6897'
abstract:
- lang: eng
text: The apical hook is a transiently formed structure that plays a protective
role when the germinating seedling penetrates through the soil towards the surface.
Crucial for proper bending is the local auxin maxima, which defines the concave
(inner) side of the hook curvature. As no sign of asymmetric auxin distribution
has been reported in embryonic hypocotyls prior to hook formation, the question
of how auxin asymmetry is established in the early phases of seedling germination
remains largely unanswered. Here, we analyzed the auxin distribution and expression
of PIN auxin efflux carriers from early phases of germination, and show that bending
of the root in response to gravity is the crucial initial cue that governs the
hypocotyl bending required for apical hook formation. Importantly, polar auxin
transport machinery is established gradually after germination starts as a result
of tight root-hypocotyl interaction and a proper balance between abscisic acid
and gibberellins.
acknowledged_ssus:
- _id: LifeSc
- _id: Bio
acknowledgement: "We thank Jiri Friml and Phillip Brewer for inspiring discussion
and for help in preparing the manuscript. This research was supported by the Scientific
Service Units (SSU) of IST-Austria through resources provided by the Bioimaging
Facility\r\n(BIF), the Life Science Facility (LSF).\r\nThis work was supported by
grants from the European Research Council (Starting Independent Research Grant ERC-2007-Stg-
207362-HCPO to E.B.). J.P. and M.S. received funds from European Regional Development
Fund-Project ‘Centre for Experimental Plant Biology’ (No. CZ.02.1.01/0.0/0.0/16_019/0000738)."
article_number: dev175919
article_processing_charge: No
article_type: original
author:
- first_name: Qiang
full_name: Zhu, Qiang
id: 40A4B9E6-F248-11E8-B48F-1D18A9856A87
last_name: Zhu
- first_name: Marçal
full_name: Gallemi, Marçal
id: 460C6802-F248-11E8-B48F-1D18A9856A87
last_name: Gallemi
orcid: 0000-0003-4675-6893
- first_name: Jiří
full_name: Pospíšil, Jiří
last_name: Pospíšil
- first_name: Petra
full_name: Žádníková, Petra
last_name: Žádníková
- first_name: Miroslav
full_name: Strnad, Miroslav
last_name: Strnad
- first_name: Eva
full_name: Benková, Eva
id: 38F4F166-F248-11E8-B48F-1D18A9856A87
last_name: Benková
orcid: 0000-0002-8510-9739
citation:
ama: Zhu Q, Gallemi M, Pospíšil J, Žádníková P, Strnad M, Benková E. Root gravity
response module guides differential growth determining both root bending and apical
hook formation in Arabidopsis. Development. 2019;146(17). doi:10.1242/dev.175919
apa: Zhu, Q., Gallemi, M., Pospíšil, J., Žádníková, P., Strnad, M., & Benková,
E. (2019). Root gravity response module guides differential growth determining
both root bending and apical hook formation in Arabidopsis. Development.
The Company of Biologists. https://doi.org/10.1242/dev.175919
chicago: Zhu, Qiang, Marçal Gallemi, Jiří Pospíšil, Petra Žádníková, Miroslav Strnad,
and Eva Benková. “Root Gravity Response Module Guides Differential Growth Determining
Both Root Bending and Apical Hook Formation in Arabidopsis.” Development.
The Company of Biologists, 2019. https://doi.org/10.1242/dev.175919.
ieee: Q. Zhu, M. Gallemi, J. Pospíšil, P. Žádníková, M. Strnad, and E. Benková,
“Root gravity response module guides differential growth determining both root
bending and apical hook formation in Arabidopsis,” Development, vol. 146,
no. 17. The Company of Biologists, 2019.
ista: Zhu Q, Gallemi M, Pospíšil J, Žádníková P, Strnad M, Benková E. 2019. Root
gravity response module guides differential growth determining both root bending
and apical hook formation in Arabidopsis. Development. 146(17), dev175919.
mla: Zhu, Qiang, et al. “Root Gravity Response Module Guides Differential Growth
Determining Both Root Bending and Apical Hook Formation in Arabidopsis.” Development,
vol. 146, no. 17, dev175919, The Company of Biologists, 2019, doi:10.1242/dev.175919.
short: Q. Zhu, M. Gallemi, J. Pospíšil, P. Žádníková, M. Strnad, E. Benková, Development
146 (2019).
date_created: 2019-09-22T22:00:36Z
date_published: 2019-09-12T00:00:00Z
date_updated: 2025-05-07T11:10:55Z
day: '12'
department:
- _id: EvBe
doi: 10.1242/dev.175919
ec_funded: 1
external_id:
isi:
- '000486297400011'
pmid:
- '31391194'
intvolume: ' 146'
isi: 1
issue: '17'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1242/dev.175919
month: '09'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 253FCA6A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '207362'
name: Hormonal cross-talk in plant organogenesis
publication: Development
publication_identifier:
eissn:
- '14779129'
publication_status: published
publisher: The Company of Biologists
quality_controlled: '1'
scopus_import: '1'
status: public
title: Root gravity response module guides differential growth determining both root
bending and apical hook formation in Arabidopsis
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 146
year: '2019'
...
---
_id: '6898'
abstract:
- lang: eng
text: "Background\r\n\r\nChlamydia are ancient intracellular pathogens with reduced,
though strikingly conserved genome. Despite their parasitic lifestyle and isolated
intracellular environment, these bacteria managed to avoid accumulation of deleterious
mutations leading to subsequent genome degradation characteristic for many parasitic
bacteria.\r\nResults\r\n\r\nWe report pan-genomic analysis of sixteen species
from genus Chlamydia including identification and functional annotation of orthologous
genes, and characterization of gene gains, losses, and rearrangements. We demonstrate
the overall genome stability of these bacteria as indicated by a large fraction
of common genes with conserved genomic locations. On the other hand, extreme evolvability
is confined to several paralogous gene families such as polymorphic membrane proteins
and phospholipase D, and likely is caused by the pressure from the host immune
system.\r\nConclusions\r\n\r\nThis combination of a large, conserved core genome
and a small, evolvable periphery likely reflect the balance between the selective
pressure towards genome reduction and the need to adapt to escape from the host
immunity."
article_number: '710'
article_processing_charge: No
author:
- first_name: Olga M.
full_name: Sigalova, Olga M.
last_name: Sigalova
- first_name: Andrei V.
full_name: Chaplin, Andrei V.
last_name: Chaplin
- first_name: Olga
full_name: Bochkareva, Olga
id: C4558D3C-6102-11E9-A62E-F418E6697425
last_name: Bochkareva
orcid: 0000-0003-1006-6639
- first_name: Pavel V.
full_name: Shelyakin, Pavel V.
last_name: Shelyakin
- first_name: Vsevolod A.
full_name: Filaretov, Vsevolod A.
last_name: Filaretov
- first_name: Evgeny E.
full_name: Akkuratov, Evgeny E.
last_name: Akkuratov
- first_name: Valentina
full_name: Burskaia, Valentina
last_name: Burskaia
- first_name: Mikhail S.
full_name: Gelfand, Mikhail S.
last_name: Gelfand
citation:
ama: Sigalova OM, Chaplin AV, Bochkareva O, et al. Chlamydia pan-genomic analysis
reveals balance between host adaptation and selective pressure to genome reduction.
BMC Genomics. 2019;20(1). doi:10.1186/s12864-019-6059-5
apa: Sigalova, O. M., Chaplin, A. V., Bochkareva, O., Shelyakin, P. V., Filaretov,
V. A., Akkuratov, E. E., … Gelfand, M. S. (2019). Chlamydia pan-genomic analysis
reveals balance between host adaptation and selective pressure to genome reduction.
BMC Genomics. BioMed Central. https://doi.org/10.1186/s12864-019-6059-5
chicago: Sigalova, Olga M., Andrei V. Chaplin, Olga Bochkareva, Pavel V. Shelyakin,
Vsevolod A. Filaretov, Evgeny E. Akkuratov, Valentina Burskaia, and Mikhail S.
Gelfand. “Chlamydia Pan-Genomic Analysis Reveals Balance between Host Adaptation
and Selective Pressure to Genome Reduction.” BMC Genomics. BioMed Central,
2019. https://doi.org/10.1186/s12864-019-6059-5.
ieee: O. M. Sigalova et al., “Chlamydia pan-genomic analysis reveals balance
between host adaptation and selective pressure to genome reduction,” BMC Genomics,
vol. 20, no. 1. BioMed Central, 2019.
ista: Sigalova OM, Chaplin AV, Bochkareva O, Shelyakin PV, Filaretov VA, Akkuratov
EE, Burskaia V, Gelfand MS. 2019. Chlamydia pan-genomic analysis reveals balance
between host adaptation and selective pressure to genome reduction. BMC Genomics.
20(1), 710.
mla: Sigalova, Olga M., et al. “Chlamydia Pan-Genomic Analysis Reveals Balance between
Host Adaptation and Selective Pressure to Genome Reduction.” BMC Genomics,
vol. 20, no. 1, 710, BioMed Central, 2019, doi:10.1186/s12864-019-6059-5.
short: O.M. Sigalova, A.V. Chaplin, O. Bochkareva, P.V. Shelyakin, V.A. Filaretov,
E.E. Akkuratov, V. Burskaia, M.S. Gelfand, BMC Genomics 20 (2019).
date_created: 2019-09-22T22:00:36Z
date_published: 2019-09-12T00:00:00Z
date_updated: 2023-08-30T06:20:22Z
day: '12'
ddc:
- '570'
department:
- _id: FyKo
doi: 10.1186/s12864-019-6059-5
external_id:
isi:
- '000485256100001'
file:
- access_level: open_access
checksum: b798773c5823012d31c812c9f7975da2
content_type: application/pdf
creator: kschuh
date_created: 2019-10-01T10:33:17Z
date_updated: 2020-07-14T12:47:44Z
file_id: '6924'
file_name: 2019_BioMed_Sigalova.pdf
file_size: 4157175
relation: main_file
file_date_updated: 2020-07-14T12:47:44Z
has_accepted_license: '1'
intvolume: ' 20'
isi: 1
issue: '1'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
publication: BMC Genomics
publication_identifier:
eissn:
- '14712164'
publication_status: published
publisher: BioMed Central
quality_controlled: '1'
related_material:
record:
- id: '9731'
relation: research_data
status: public
- id: '9783'
relation: research_data
status: public
- id: '9890'
relation: research_data
status: public
- id: '9892'
relation: research_data
status: public
- id: '9893'
relation: research_data
status: public
- id: '9894'
relation: research_data
status: public
- id: '9895'
relation: research_data
status: public
- id: '9896'
relation: research_data
status: public
- id: '9897'
relation: research_data
status: public
- id: '9898'
relation: research_data
status: public
- id: '9899'
relation: research_data
status: public
- id: '9900'
relation: research_data
status: public
- id: '9901'
relation: research_data
status: public
scopus_import: '1'
status: public
title: Chlamydia pan-genomic analysis reveals balance between host adaptation and
selective pressure to genome reduction
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 20
year: '2019'
...
---
_id: '6899'
abstract:
- lang: eng
text: Intra-organ communication guides morphogenetic processes that are essential
for an organ to carry out complex physiological functions. In the heart, the growth
of the myocardium is tightly coupled to that of the endocardium, a specialized
endothelial tissue that lines its interior. Several molecular pathways have been
implicated in the communication between these tissues including secreted factors,
components of the extracellular matrix, or proteins involved in cell-cell communication.
Yet, it is unknown how the growth of the endocardium is coordinated with that
of the myocardium. Here, we show that an increased expansion of the myocardial
atrial chamber volume generates higher junctional forces within endocardial cells.
This leads to biomechanical signaling involving VE-cadherin, triggering nuclear
localization of the Hippo pathway transcriptional regulator Yap1 and endocardial
proliferation. Our work suggests that the growth of the endocardium results from
myocardial chamber volume expansion and ends when the tension on the tissue is
relaxed.
article_processing_charge: No
author:
- first_name: Dorothee
full_name: Bornhorst, Dorothee
last_name: Bornhorst
- first_name: Peng
full_name: Xia, Peng
id: 4AB6C7D0-F248-11E8-B48F-1D18A9856A87
last_name: Xia
orcid: 0000-0002-5419-7756
- first_name: Hiroyuki
full_name: Nakajima, Hiroyuki
last_name: Nakajima
- first_name: Chaitanya
full_name: Dingare, Chaitanya
last_name: Dingare
- first_name: Wiebke
full_name: Herzog, Wiebke
last_name: Herzog
- first_name: Virginie
full_name: Lecaudey, Virginie
last_name: Lecaudey
- first_name: Naoki
full_name: Mochizuki, Naoki
last_name: Mochizuki
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
- first_name: Deborah
full_name: Yelon, Deborah
last_name: Yelon
- first_name: Salim
full_name: Abdelilah-Seyfried, Salim
last_name: Abdelilah-Seyfried
citation:
ama: Bornhorst D, Xia P, Nakajima H, et al. Biomechanical signaling within the developing
zebrafish heart attunes endocardial growth to myocardial chamber dimensions. Nature
communications. 2019;10(1):4113. doi:10.1038/s41467-019-12068-x
apa: Bornhorst, D., Xia, P., Nakajima, H., Dingare, C., Herzog, W., Lecaudey, V.,
… Abdelilah-Seyfried, S. (2019). Biomechanical signaling within the developing
zebrafish heart attunes endocardial growth to myocardial chamber dimensions. Nature
Communications. Nature Publishing Group. https://doi.org/10.1038/s41467-019-12068-x
chicago: Bornhorst, Dorothee, Peng Xia, Hiroyuki Nakajima, Chaitanya Dingare, Wiebke
Herzog, Virginie Lecaudey, Naoki Mochizuki, Carl-Philipp J Heisenberg, Deborah
Yelon, and Salim Abdelilah-Seyfried. “Biomechanical Signaling within the Developing
Zebrafish Heart Attunes Endocardial Growth to Myocardial Chamber Dimensions.”
Nature Communications. Nature Publishing Group, 2019. https://doi.org/10.1038/s41467-019-12068-x.
ieee: D. Bornhorst et al., “Biomechanical signaling within the developing
zebrafish heart attunes endocardial growth to myocardial chamber dimensions,”
Nature communications, vol. 10, no. 1. Nature Publishing Group, p. 4113,
2019.
ista: Bornhorst D, Xia P, Nakajima H, Dingare C, Herzog W, Lecaudey V, Mochizuki
N, Heisenberg C-PJ, Yelon D, Abdelilah-Seyfried S. 2019. Biomechanical signaling
within the developing zebrafish heart attunes endocardial growth to myocardial
chamber dimensions. Nature communications. 10(1), 4113.
mla: Bornhorst, Dorothee, et al. “Biomechanical Signaling within the Developing
Zebrafish Heart Attunes Endocardial Growth to Myocardial Chamber Dimensions.”
Nature Communications, vol. 10, no. 1, Nature Publishing Group, 2019, p.
4113, doi:10.1038/s41467-019-12068-x.
short: D. Bornhorst, P. Xia, H. Nakajima, C. Dingare, W. Herzog, V. Lecaudey, N.
Mochizuki, C.-P.J. Heisenberg, D. Yelon, S. Abdelilah-Seyfried, Nature Communications
10 (2019) 4113.
date_created: 2019-09-22T22:00:37Z
date_published: 2019-09-11T00:00:00Z
date_updated: 2023-08-30T06:21:23Z
day: '11'
ddc:
- '570'
department:
- _id: CaHe
doi: 10.1038/s41467-019-12068-x
external_id:
isi:
- '000485216800009'
pmid:
- '31511517'
file:
- access_level: open_access
checksum: 62c2512712e16d27c1797d318d14ba9f
content_type: application/pdf
creator: kschuh
date_created: 2019-10-01T11:18:50Z
date_updated: 2020-07-14T12:47:44Z
file_id: '6926'
file_name: 2019_Nature_Bornhorst.pdf
file_size: 3905793
relation: main_file
file_date_updated: 2020-07-14T12:47:44Z
has_accepted_license: '1'
intvolume: ' 10'
isi: 1
issue: '1'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: '4113'
pmid: 1
publication: Nature communications
publication_identifier:
eissn:
- '20411723'
publication_status: published
publisher: Nature Publishing Group
quality_controlled: '1'
scopus_import: '1'
status: public
title: Biomechanical signaling within the developing zebrafish heart attunes endocardial
growth to myocardial chamber dimensions
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 10
year: '2019'
...
---
_id: '6900'
abstract:
- lang: eng
text: Across diverse biological systems—ranging from neural networks to intracellular
signaling and genetic regulatory networks—the information about changes in the
environment is frequently encoded in the full temporal dynamics of the network
nodes. A pressing data-analysis challenge has thus been to efficiently estimate
the amount of information that these dynamics convey from experimental data. Here
we develop and evaluate decoding-based estimation methods to lower bound the mutual
information about a finite set of inputs, encoded in single-cell high-dimensional
time series data. For biological reaction networks governed by the chemical Master
equation, we derive model-based information approximations and analytical upper
bounds, against which we benchmark our proposed model-free decoding estimators.
In contrast to the frequently-used k-nearest-neighbor estimator, decoding-based
estimators robustly extract a large fraction of the available information from
high-dimensional trajectories with a realistic number of data samples. We apply
these estimators to previously published data on Erk and Ca2+ signaling in mammalian
cells and to yeast stress-response, and find that substantial amount of information
about environmental state can be encoded by non-trivial response statistics even
in stationary signals. We argue that these single-cell, decoding-based information
estimates, rather than the commonly-used tests for significant differences between
selected population response statistics, provide a proper and unbiased measure
for the performance of biological signaling networks.
article_processing_charge: No
author:
- first_name: Sarah A
full_name: Cepeda Humerez, Sarah A
id: 3DEE19A4-F248-11E8-B48F-1D18A9856A87
last_name: Cepeda Humerez
- first_name: Jakob
full_name: Ruess, Jakob
last_name: Ruess
orcid: 0000-0003-1615-3282
- first_name: Gašper
full_name: Tkačik, Gašper
id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
last_name: Tkačik
orcid: 0000-0002-6699-1455
citation:
ama: Cepeda Humerez SA, Ruess J, Tkačik G. Estimating information in time-varying
signals. PLoS computational biology. 2019;15(9):e1007290. doi:10.1371/journal.pcbi.1007290
apa: Cepeda Humerez, S. A., Ruess, J., & Tkačik, G. (2019). Estimating information
in time-varying signals. PLoS Computational Biology. Public Library of
Science. https://doi.org/10.1371/journal.pcbi.1007290
chicago: Cepeda Humerez, Sarah A, Jakob Ruess, and Gašper Tkačik. “Estimating Information
in Time-Varying Signals.” PLoS Computational Biology. Public Library of
Science, 2019. https://doi.org/10.1371/journal.pcbi.1007290.
ieee: S. A. Cepeda Humerez, J. Ruess, and G. Tkačik, “Estimating information in
time-varying signals,” PLoS computational biology, vol. 15, no. 9. Public
Library of Science, p. e1007290, 2019.
ista: Cepeda Humerez SA, Ruess J, Tkačik G. 2019. Estimating information in time-varying
signals. PLoS computational biology. 15(9), e1007290.
mla: Cepeda Humerez, Sarah A., et al. “Estimating Information in Time-Varying Signals.”
PLoS Computational Biology, vol. 15, no. 9, Public Library of Science,
2019, p. e1007290, doi:10.1371/journal.pcbi.1007290.
short: S.A. Cepeda Humerez, J. Ruess, G. Tkačik, PLoS Computational Biology 15 (2019)
e1007290.
date_created: 2019-09-22T22:00:37Z
date_published: 2019-09-03T00:00:00Z
date_updated: 2023-09-07T12:55:21Z
day: '03'
ddc:
- '570'
department:
- _id: GaTk
doi: 10.1371/journal.pcbi.1007290
external_id:
isi:
- '000489741800021'
pmid:
- '31479447'
file:
- access_level: open_access
checksum: 81bdce1361c9aa8395d6fa635fb6ab47
content_type: application/pdf
creator: kschuh
date_created: 2019-10-01T10:53:45Z
date_updated: 2020-07-14T12:47:44Z
file_id: '6925'
file_name: 2019_PLoS_Cepeda-Humerez.pdf
file_size: 3081855
relation: main_file
file_date_updated: 2020-07-14T12:47:44Z
has_accepted_license: '1'
intvolume: ' 15'
isi: 1
issue: '9'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: e1007290
pmid: 1
project:
- _id: 254E9036-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P28844-B27
name: Biophysics of information processing in gene regulation
publication: PLoS computational biology
publication_identifier:
eissn:
- '15537358'
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
related_material:
record:
- id: '6473'
relation: part_of_dissertation
status: public
scopus_import: '1'
status: public
title: Estimating information in time-varying signals
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 15
year: '2019'
...
---
_id: '10065'
abstract:
- lang: eng
text: We study double quantum dots in a Ge/SiGe heterostructure and test their maturity
towards singlet-triplet ($S-T_0$) qubits. We demonstrate a large range of tunability,
from two single quantum dots to a double quantum dot. We measure Pauli spin blockade
and study the anisotropy of the $g$-factor. We use an adjacent quantum dot for
sensing charge transitions in the double quantum dot at interest. In conclusion,
Ge/SiGe possesses all ingredients necessary for building a singlet-triplet qubit.
acknowledged_ssus:
- _id: M-Shop
- _id: NanoFab
acknowledgement: "We thank Matthias Brauns for helpful discussions and careful proofreading
of the manuscript. This project has received funding from the European Union’s Horizon
2020 research and innovation program under the Marie Sklodowska-Curie grant agreement
No 844511 and from the FWF project P30207. The research was supported by the Scientific
Service Units of IST Austria through resources provided by the MIBA machine shop
and the nanofabrication\r\nfacility."
article_number: '1910.05841'
article_processing_charge: No
arxiv: 1
author:
- first_name: Andrea C
full_name: Hofmann, Andrea C
id: 340F461A-F248-11E8-B48F-1D18A9856A87
last_name: Hofmann
- first_name: Daniel
full_name: Jirovec, Daniel
id: 4C473F58-F248-11E8-B48F-1D18A9856A87
last_name: Jirovec
orcid: 0000-0002-7197-4801
- first_name: Maxim
full_name: Borovkov, Maxim
last_name: Borovkov
- first_name: Ivan
full_name: Prieto Gonzalez, Ivan
id: 2A307FE2-F248-11E8-B48F-1D18A9856A87
last_name: Prieto Gonzalez
orcid: 0000-0002-7370-5357
- first_name: Andrea
full_name: Ballabio, Andrea
last_name: Ballabio
- first_name: Jacopo
full_name: Frigerio, Jacopo
last_name: Frigerio
- first_name: Daniel
full_name: Chrastina, Daniel
last_name: Chrastina
- first_name: Giovanni
full_name: Isella, Giovanni
last_name: Isella
- first_name: Georgios
full_name: Katsaros, Georgios
id: 38DB5788-F248-11E8-B48F-1D18A9856A87
last_name: Katsaros
orcid: 0000-0001-8342-202X
citation:
ama: Hofmann AC, Jirovec D, Borovkov M, et al. Assessing the potential of Ge/SiGe
quantum dots as hosts for singlet-triplet qubits. arXiv. doi:10.48550/arXiv.1910.05841
apa: Hofmann, A. C., Jirovec, D., Borovkov, M., Prieto Gonzalez, I., Ballabio, A.,
Frigerio, J., … Katsaros, G. (n.d.). Assessing the potential of Ge/SiGe quantum
dots as hosts for singlet-triplet qubits. arXiv. https://doi.org/10.48550/arXiv.1910.05841
chicago: Hofmann, Andrea C, Daniel Jirovec, Maxim Borovkov, Ivan Prieto Gonzalez,
Andrea Ballabio, Jacopo Frigerio, Daniel Chrastina, Giovanni Isella, and Georgios
Katsaros. “Assessing the Potential of Ge/SiGe Quantum Dots as Hosts for Singlet-Triplet
Qubits.” ArXiv, n.d. https://doi.org/10.48550/arXiv.1910.05841.
ieee: A. C. Hofmann et al., “Assessing the potential of Ge/SiGe quantum dots
as hosts for singlet-triplet qubits,” arXiv. .
ista: Hofmann AC, Jirovec D, Borovkov M, Prieto Gonzalez I, Ballabio A, Frigerio
J, Chrastina D, Isella G, Katsaros G. Assessing the potential of Ge/SiGe quantum
dots as hosts for singlet-triplet qubits. arXiv, 1910.05841.
mla: Hofmann, Andrea C., et al. “Assessing the Potential of Ge/SiGe Quantum Dots
as Hosts for Singlet-Triplet Qubits.” ArXiv, 1910.05841, doi:10.48550/arXiv.1910.05841.
short: A.C. Hofmann, D. Jirovec, M. Borovkov, I. Prieto Gonzalez, A. Ballabio, J.
Frigerio, D. Chrastina, G. Isella, G. Katsaros, ArXiv (n.d.).
date_created: 2021-10-01T12:14:51Z
date_published: 2019-10-13T00:00:00Z
date_updated: 2024-03-25T23:30:14Z
day: '13'
department:
- _id: GeKa
doi: 10.48550/arXiv.1910.05841
ec_funded: 1
external_id:
arxiv:
- '1910.05841'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1910.05841
month: '10'
oa: 1
oa_version: Preprint
project:
- _id: 26A151DA-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '844511'
name: Majorana bound states in Ge/SiGe heterostructures
- _id: 2641CE5E-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P30207
name: Hole spin orbit qubits in Ge quantum wells
publication: arXiv
publication_status: submitted
related_material:
record:
- id: '10058'
relation: dissertation_contains
status: public
status: public
title: Assessing the potential of Ge/SiGe quantum dots as hosts for singlet-triplet
qubits
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2019'
...
---
_id: '10190'
abstract:
- lang: eng
text: 'The verification of concurrent programs remains an open challenge, as thread
interaction has to be accounted for, which leads to state-space explosion. Stateless
model checking battles this problem by exploring traces rather than states of
the program. As there are exponentially many traces, dynamic partial-order reduction
(DPOR) techniques are used to partition the trace space into equivalence classes,
and explore a few representatives from each class. The standard equivalence that
underlies most DPOR techniques is the happens-before equivalence, however recent
works have spawned a vivid interest towards coarser equivalences. The efficiency
of such approaches is a product of two parameters: (i) the size of the partitioning
induced by the equivalence, and (ii) the time spent by the exploration algorithm
in each class of the partitioning. In this work, we present a new equivalence,
called value-happens-before and show that it has two appealing features. First,
value-happens-before is always at least as coarse as the happens-before equivalence,
and can be even exponentially coarser. Second, the value-happens-before partitioning
is efficiently explorable when the number of threads is bounded. We present an
algorithm called value-centric DPOR (VCDPOR), which explores the underlying partitioning
using polynomial time per class. Finally, we perform an experimental evaluation
of VCDPOR on various benchmarks, and compare it against other state-of-the-art
approaches. Our results show that value-happens-before typically induces a significant
reduction in the size of the underlying partitioning, which leads to a considerable
reduction in the running time for exploring the whole partitioning.'
acknowledgement: "The authors would also like to thank anonymous referees for their
valuable comments and helpful suggestions. This work is supported by the Austrian
Science Fund (FWF) NFN grants S11407-N23 (RiSE/SHiNE) and S11402-N23 (RiSE/SHiNE),
by the Vienna Science and Technology Fund (WWTF) Project ICT15-003, and by the Austrian
Science Fund (FWF) Schrodinger grant J-4220.\r\n"
article_number: '124'
article_processing_charge: No
arxiv: 1
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Andreas
full_name: Pavlogiannis, Andreas
id: 49704004-F248-11E8-B48F-1D18A9856A87
last_name: Pavlogiannis
orcid: 0000-0002-8943-0722
- first_name: Viktor
full_name: Toman, Viktor
id: 3AF3DA7C-F248-11E8-B48F-1D18A9856A87
last_name: Toman
orcid: 0000-0001-9036-063X
citation:
ama: 'Chatterjee K, Pavlogiannis A, Toman V. Value-centric dynamic partial order
reduction. In: Proceedings of the 34th ACM International Conference on Object-Oriented
Programming, Systems, Languages, and Applications. Vol 3. ACM; 2019. doi:10.1145/3360550'
apa: 'Chatterjee, K., Pavlogiannis, A., & Toman, V. (2019). Value-centric dynamic
partial order reduction. In Proceedings of the 34th ACM International Conference
on Object-Oriented Programming, Systems, Languages, and Applications (Vol.
3). Athens, Greece: ACM. https://doi.org/10.1145/3360550'
chicago: Chatterjee, Krishnendu, Andreas Pavlogiannis, and Viktor Toman. “Value-Centric
Dynamic Partial Order Reduction.” In Proceedings of the 34th ACM International
Conference on Object-Oriented Programming, Systems, Languages, and Applications,
Vol. 3. ACM, 2019. https://doi.org/10.1145/3360550.
ieee: K. Chatterjee, A. Pavlogiannis, and V. Toman, “Value-centric dynamic partial
order reduction,” in Proceedings of the 34th ACM International Conference on
Object-Oriented Programming, Systems, Languages, and Applications, Athens,
Greece, 2019, vol. 3.
ista: 'Chatterjee K, Pavlogiannis A, Toman V. 2019. Value-centric dynamic partial
order reduction. Proceedings of the 34th ACM International Conference on Object-Oriented
Programming, Systems, Languages, and Applications. OOPSLA: Object-oriented Programming,
Systems, Languages and Applications vol. 3, 124.'
mla: Chatterjee, Krishnendu, et al. “Value-Centric Dynamic Partial Order Reduction.”
Proceedings of the 34th ACM International Conference on Object-Oriented Programming,
Systems, Languages, and Applications, vol. 3, 124, ACM, 2019, doi:10.1145/3360550.
short: K. Chatterjee, A. Pavlogiannis, V. Toman, in:, Proceedings of the 34th ACM
International Conference on Object-Oriented Programming, Systems, Languages, and
Applications, ACM, 2019.
conference:
end_date: 2019-10-25
location: Athens, Greece
name: 'OOPSLA: Object-oriented Programming, Systems, Languages and Applications'
start_date: 2019-10-23
date_created: 2021-10-27T14:57:06Z
date_published: 2019-10-10T00:00:00Z
date_updated: 2025-07-14T09:10:15Z
day: '10'
ddc:
- '000'
department:
- _id: GradSch
- _id: KrCh
doi: 10.1145/3360550
external_id:
arxiv:
- '1909.00989'
file:
- access_level: open_access
checksum: 2149979c46964c4d117af06ccb6c0834
content_type: application/pdf
creator: cchlebak
date_created: 2021-11-12T11:41:56Z
date_updated: 2021-11-12T11:41:56Z
file_id: '10278'
file_name: 2019_ACM_Chatterjee.pdf
file_size: 570829
relation: main_file
success: 1
file_date_updated: 2021-11-12T11:41:56Z
has_accepted_license: '1'
intvolume: ' 3'
keyword:
- safety
- risk
- reliability and quality
- software
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://dl.acm.org/doi/10.1145/3360550
month: '10'
oa: 1
oa_version: Published Version
project:
- _id: 25892FC0-B435-11E9-9278-68D0E5697425
grant_number: ICT15-003
name: Efficient Algorithms for Computer Aided Verification
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11407
name: Game Theory
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 25F5A88A-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11402-N23
name: Moderne Concurrency Paradigms
publication: Proceedings of the 34th ACM International Conference on Object-Oriented
Programming, Systems, Languages, and Applications
publication_identifier:
eissn:
- 2475-1421
publication_status: published
publisher: ACM
quality_controlled: '1'
related_material:
record:
- id: '10199'
relation: dissertation_contains
status: public
status: public
title: Value-centric dynamic partial order reduction
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 3
year: '2019'
...
---
_id: '10354'
abstract:
- lang: eng
text: "Background\r\nESCRT-III is a membrane remodelling filament with the unique
ability to cut membranes from the inside of the membrane neck. It is essential
for the final stage of cell division, the formation of vesicles, the release of
viruses, and membrane repair. Distinct from other cytoskeletal filaments, ESCRT-III
filaments do not consume energy themselves, but work in conjunction with another
ATP-consuming complex. Despite rapid progress in describing the cell biology of
ESCRT-III, we lack an understanding of the physical mechanisms behind its force
production and membrane remodelling.\r\nResults\r\nHere we present a minimal coarse-grained
model that captures all the experimentally reported cases of ESCRT-III driven
membrane sculpting, including the formation of downward and upward cones and tubules.
This model suggests that a change in the geometry of membrane bound ESCRT-III
filaments—from a flat spiral to a 3D helix—drives membrane deformation. We then
show that such repetitive filament geometry transitions can induce the fission
of cargo-containing vesicles.\r\nConclusions\r\nOur model provides a general physical
mechanism that explains the full range of ESCRT-III-dependent membrane remodelling
and scission events observed in cells. This mechanism for filament force production
is distinct from the mechanisms described for other cytoskeletal elements discovered
so far. The mechanistic principles revealed here suggest new ways of manipulating
ESCRT-III-driven processes in cells and could be used to guide the engineering
of synthetic membrane-sculpting systems."
acknowledgement: We thank Jeremy Carlton, Mike Staddon, Geraint Harker, and the Wellcome
Trust Consortium “Archaeal Origins of Eukaryotic Cell Organisation” for fruitful
conversations. We thank Peter Wirnsberger and Tine Curk for discussions about the
membrane model implementation.
article_number: '82'
article_processing_charge: No
article_type: original
author:
- first_name: Lena
full_name: Harker-Kirschneck, Lena
last_name: Harker-Kirschneck
- first_name: Buzz
full_name: Baum, Buzz
last_name: Baum
- first_name: Anđela
full_name: Šarić, Anđela
id: bf63d406-f056-11eb-b41d-f263a6566d8b
last_name: Šarić
orcid: 0000-0002-7854-2139
citation:
ama: Harker-Kirschneck L, Baum B, Šarić A. Changes in ESCRT-III filament geometry
drive membrane remodelling and fission in silico. BMC Biology. 2019;17(1).
doi:10.1186/s12915-019-0700-2
apa: Harker-Kirschneck, L., Baum, B., & Šarić, A. (2019). Changes in ESCRT-III
filament geometry drive membrane remodelling and fission in silico. BMC Biology.
Springer Nature. https://doi.org/10.1186/s12915-019-0700-2
chicago: Harker-Kirschneck, Lena, Buzz Baum, and Anđela Šarić. “Changes in ESCRT-III
Filament Geometry Drive Membrane Remodelling and Fission in Silico.” BMC Biology.
Springer Nature, 2019. https://doi.org/10.1186/s12915-019-0700-2.
ieee: L. Harker-Kirschneck, B. Baum, and A. Šarić, “Changes in ESCRT-III filament
geometry drive membrane remodelling and fission in silico,” BMC Biology,
vol. 17, no. 1. Springer Nature, 2019.
ista: Harker-Kirschneck L, Baum B, Šarić A. 2019. Changes in ESCRT-III filament
geometry drive membrane remodelling and fission in silico. BMC Biology. 17(1),
82.
mla: Harker-Kirschneck, Lena, et al. “Changes in ESCRT-III Filament Geometry Drive
Membrane Remodelling and Fission in Silico.” BMC Biology, vol. 17, no.
1, 82, Springer Nature, 2019, doi:10.1186/s12915-019-0700-2.
short: L. Harker-Kirschneck, B. Baum, A. Šarić, BMC Biology 17 (2019).
date_created: 2021-11-26T11:25:03Z
date_published: 2019-10-22T00:00:00Z
date_updated: 2021-11-26T11:54:29Z
day: '22'
ddc:
- '570'
doi: 10.1186/s12915-019-0700-2
extern: '1'
external_id:
pmid:
- '31640700'
file:
- access_level: open_access
checksum: 31d8bae55a376d30925f53f7e1a02396
content_type: application/pdf
creator: cchlebak
date_created: 2021-11-26T11:37:54Z
date_updated: 2021-11-26T11:37:54Z
file_id: '10356'
file_name: 2019_BMCBio_Harker_Kirschneck.pdf
file_size: 1648926
relation: main_file
success: 1
file_date_updated: 2021-11-26T11:37:54Z
has_accepted_license: '1'
intvolume: ' 17'
issue: '1'
keyword:
- cell biology
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.biorxiv.org/content/10.1101/559898
month: '10'
oa: 1
oa_version: Published Version
pmid: 1
publication: BMC Biology
publication_identifier:
issn:
- 1741-7007
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Changes in ESCRT-III filament geometry drive membrane remodelling and fission
in silico
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 17
year: '2019'
...
---
_id: '10355'
abstract:
- lang: eng
text: The molecular machinery of life is largely created via self-organisation of
individual molecules into functional assemblies. Minimal coarse-grained models,
in which a whole macromolecule is represented by a small number of particles,
can be of great value in identifying the main driving forces behind self-organisation
in cell biology. Such models can incorporate data from both molecular and continuum
scales, and their results can be directly compared to experiments. Here we review
the state of the art of models for studying the formation and biological function
of macromolecular assemblies in living organisms. We outline the key ingredients
of each model and their main findings. We illustrate the contribution of this
class of simulations to identifying the physical mechanisms behind life and diseases,
and discuss their future developments.
acknowledgement: We acknowledge funding from EPSRC (A.E.H. and A.Š.), the Academy
of Medical Sciences (J.K. and A.Š.), the Wellcome Trust (J.K. and A.Š.), and the
Royal Society (A.Š.). We thank Shiladitya Banerjee and Nikola Ojkic for critically
reading the manuscript, and Claudia Flandoli for helping us with figures and illustrations.
article_processing_charge: No
article_type: original
author:
- first_name: Anne E
full_name: Hafner, Anne E
last_name: Hafner
- first_name: Johannes
full_name: Krausser, Johannes
last_name: Krausser
- first_name: Anđela
full_name: Šarić, Anđela
id: bf63d406-f056-11eb-b41d-f263a6566d8b
last_name: Šarić
orcid: 0000-0002-7854-2139
citation:
ama: Hafner AE, Krausser J, Šarić A. Minimal coarse-grained models for molecular
self-organisation in biology. Current Opinion in Structural Biology. 2019;58:43-52.
doi:10.1016/j.sbi.2019.05.018
apa: Hafner, A. E., Krausser, J., & Šarić, A. (2019). Minimal coarse-grained
models for molecular self-organisation in biology. Current Opinion in Structural
Biology. Elsevier. https://doi.org/10.1016/j.sbi.2019.05.018
chicago: Hafner, Anne E, Johannes Krausser, and Anđela Šarić. “Minimal Coarse-Grained
Models for Molecular Self-Organisation in Biology.” Current Opinion in Structural
Biology. Elsevier, 2019. https://doi.org/10.1016/j.sbi.2019.05.018.
ieee: A. E. Hafner, J. Krausser, and A. Šarić, “Minimal coarse-grained models for
molecular self-organisation in biology,” Current Opinion in Structural Biology,
vol. 58. Elsevier, pp. 43–52, 2019.
ista: Hafner AE, Krausser J, Šarić A. 2019. Minimal coarse-grained models for molecular
self-organisation in biology. Current Opinion in Structural Biology. 58, 43–52.
mla: Hafner, Anne E., et al. “Minimal Coarse-Grained Models for Molecular Self-Organisation
in Biology.” Current Opinion in Structural Biology, vol. 58, Elsevier,
2019, pp. 43–52, doi:10.1016/j.sbi.2019.05.018.
short: A.E. Hafner, J. Krausser, A. Šarić, Current Opinion in Structural Biology
58 (2019) 43–52.
date_created: 2021-11-26T11:33:21Z
date_published: 2019-06-18T00:00:00Z
date_updated: 2021-11-26T11:54:25Z
day: '18'
doi: 10.1016/j.sbi.2019.05.018
extern: '1'
external_id:
pmid:
- '31226513'
intvolume: ' 58'
keyword:
- molecular biology
- structural biology
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1906.09349
month: '06'
oa: 1
oa_version: Preprint
page: 43-52
pmid: 1
publication: Current Opinion in Structural Biology
publication_identifier:
issn:
- 0959-440X
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Minimal coarse-grained models for molecular self-organisation in biology
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 58
year: '2019'
...
---
_id: '105'
abstract:
- lang: eng
text: 'Clinical Utility Gene Card. 1. Name of Disease (Synonyms): Pontocerebellar
hypoplasia type 9 (PCH9) and spastic paraplegia-63 (SPG63). 2. OMIM# of the Disease:
615809 and 615686. 3. Name of the Analysed Genes or DNA/Chromosome Segments: AMPD2
at 1p13.3. 4. OMIM# of the Gene(s): 102771.'
acknowledgement: 'This work was supported by EuroGentest2 (Unit 2: “Genetic testing
as part of health care”), a Coordination Action under FP7 (Grant Agreement Number
261469) and the European Society of Human Genetics. We acknowledge the participation
of the patients and their families in these studies, as well as the generous financial
support of the Lefroy and Handbury families. APLM was supported by an Australian
Postgraduate Award. PJL is supported by an NHMRC Career Development Fellowship (GNT1032364).
RJL is supported by a Melbourne Children’s Clinician Scientist Fellowship.'
article_processing_charge: No
article_type: original
author:
- first_name: Ashley
full_name: Marsh, Ashley
last_name: Marsh
- first_name: Gaia
full_name: Novarino, Gaia
id: 3E57A680-F248-11E8-B48F-1D18A9856A87
last_name: Novarino
orcid: 0000-0002-7673-7178
- first_name: Paul
full_name: Lockhart, Paul
last_name: Lockhart
- first_name: Richard
full_name: Leventer, Richard
last_name: Leventer
citation:
ama: Marsh A, Novarino G, Lockhart P, Leventer R. CUGC for pontocerebellar hypoplasia
type 9 and spastic paraplegia-63. European Journal of Human Genetics. 2019;27:161-166.
doi:10.1038/s41431-018-0231-2
apa: Marsh, A., Novarino, G., Lockhart, P., & Leventer, R. (2019). CUGC for
pontocerebellar hypoplasia type 9 and spastic paraplegia-63. European Journal
of Human Genetics. Springer Nature. https://doi.org/10.1038/s41431-018-0231-2
chicago: Marsh, Ashley, Gaia Novarino, Paul Lockhart, and Richard Leventer. “CUGC
for Pontocerebellar Hypoplasia Type 9 and Spastic Paraplegia-63.” European
Journal of Human Genetics. Springer Nature, 2019. https://doi.org/10.1038/s41431-018-0231-2.
ieee: A. Marsh, G. Novarino, P. Lockhart, and R. Leventer, “CUGC for pontocerebellar
hypoplasia type 9 and spastic paraplegia-63,” European Journal of Human Genetics,
vol. 27. Springer Nature, pp. 161–166, 2019.
ista: Marsh A, Novarino G, Lockhart P, Leventer R. 2019. CUGC for pontocerebellar
hypoplasia type 9 and spastic paraplegia-63. European Journal of Human Genetics.
27, 161–166.
mla: Marsh, Ashley, et al. “CUGC for Pontocerebellar Hypoplasia Type 9 and Spastic
Paraplegia-63.” European Journal of Human Genetics, vol. 27, Springer Nature,
2019, pp. 161–66, doi:10.1038/s41431-018-0231-2.
short: A. Marsh, G. Novarino, P. Lockhart, R. Leventer, European Journal of Human
Genetics 27 (2019) 161–166.
date_created: 2018-12-11T11:44:39Z
date_published: 2019-01-01T00:00:00Z
date_updated: 2023-08-24T14:28:24Z
day: '01'
department:
- _id: GaNo
doi: 10.1038/s41431-018-0231-2
external_id:
isi:
- '000454111500019'
pmid:
- '30089829'
intvolume: ' 27'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1038/s41431-018-0231-2
month: '01'
oa: 1
oa_version: Published Version
page: 161-166
pmid: 1
publication: European Journal of Human Genetics
publication_status: published
publisher: Springer Nature
publist_id: '7949'
quality_controlled: '1'
scopus_import: '1'
status: public
title: CUGC for pontocerebellar hypoplasia type 9 and spastic paraplegia-63
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 27
year: '2019'
...
---
_id: '10619'
abstract:
- lang: eng
text: The quantum anomalous Hall (QAH) effect combines topology and magnetism to
produce precisely quantized Hall resistance at zero magnetic field. We report
the observation of a QAH effect in twisted bilayer graphene aligned to hexagonal
boron nitride. The effect is driven by intrinsic strong interactions, which polarize
the electrons into a single spin- and valley-resolved moiré miniband with Chern
number C = 1. In contrast to magnetically doped systems, the measured transport
energy gap is larger than the Curie temperature for magnetic ordering, and quantization
to within 0.1% of the von Klitzing constant persists to temperatures of several
kelvin at zero magnetic field. Electrical currents as small as 1 nanoampere controllably
switch the magnetic order between states of opposite polarization, forming an
electrically rewritable magnetic memory.
acknowledgement: The authors acknowledge discussions with A. Macdonald, Y. Saito,
and M. Zaletel.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: M.
full_name: Serlin, M.
last_name: Serlin
- first_name: C. L.
full_name: Tschirhart, C. L.
last_name: Tschirhart
- first_name: Hryhoriy
full_name: Polshyn, Hryhoriy
id: edfc7cb1-526e-11ec-b05a-e6ecc27e4e48
last_name: Polshyn
orcid: 0000-0001-8223-8896
- first_name: Y.
full_name: Zhang, Y.
last_name: Zhang
- first_name: J.
full_name: Zhu, J.
last_name: Zhu
- first_name: K.
full_name: Watanabe, K.
last_name: Watanabe
- first_name: T.
full_name: Taniguchi, T.
last_name: Taniguchi
- first_name: L.
full_name: Balents, L.
last_name: Balents
- first_name: A. F.
full_name: Young, A. F.
last_name: Young
citation:
ama: Serlin M, Tschirhart CL, Polshyn H, et al. Intrinsic quantized anomalous Hall
effect in a moiré heterostructure. Science. 2019;367(6480):900-903. doi:10.1126/science.aay5533
apa: Serlin, M., Tschirhart, C. L., Polshyn, H., Zhang, Y., Zhu, J., Watanabe, K.,
… Young, A. F. (2019). Intrinsic quantized anomalous Hall effect in a moiré heterostructure.
Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.aay5533
chicago: Serlin, M., C. L. Tschirhart, Hryhoriy Polshyn, Y. Zhang, J. Zhu, K. Watanabe,
T. Taniguchi, L. Balents, and A. F. Young. “Intrinsic Quantized Anomalous Hall
Effect in a Moiré Heterostructure.” Science. American Association for the
Advancement of Science, 2019. https://doi.org/10.1126/science.aay5533.
ieee: M. Serlin et al., “Intrinsic quantized anomalous Hall effect in a moiré
heterostructure,” Science, vol. 367, no. 6480. American Association for
the Advancement of Science, pp. 900–903, 2019.
ista: Serlin M, Tschirhart CL, Polshyn H, Zhang Y, Zhu J, Watanabe K, Taniguchi
T, Balents L, Young AF. 2019. Intrinsic quantized anomalous Hall effect in a moiré
heterostructure. Science. 367(6480), 900–903.
mla: Serlin, M., et al. “Intrinsic Quantized Anomalous Hall Effect in a Moiré Heterostructure.”
Science, vol. 367, no. 6480, American Association for the Advancement of
Science, 2019, pp. 900–03, doi:10.1126/science.aay5533.
short: M. Serlin, C.L. Tschirhart, H. Polshyn, Y. Zhang, J. Zhu, K. Watanabe, T.
Taniguchi, L. Balents, A.F. Young, Science 367 (2019) 900–903.
date_created: 2022-01-13T14:21:32Z
date_published: 2019-12-19T00:00:00Z
date_updated: 2023-02-21T16:00:09Z
day: '19'
doi: 10.1126/science.aay5533
extern: '1'
external_id:
arxiv:
- '1907.00261'
pmid:
- '31857492'
intvolume: ' 367'
issue: '6480'
keyword:
- multidisciplinary
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1907.00261
month: '12'
oa: 1
oa_version: Preprint
page: 900-903
pmid: 1
publication: Science
publication_identifier:
eissn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
related_material:
record:
- id: '10697'
relation: other
status: public
- id: '10698'
relation: other
status: public
- id: '10699'
relation: other
status: public
scopus_import: '1'
status: public
title: Intrinsic quantized anomalous Hall effect in a moiré heterostructure
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 367
year: '2019'
...
---
_id: '10620'
abstract:
- lang: eng
text: Partially filled Landau levels host competing electronic orders. For example,
electron solids may prevail close to integer filling of the Landau levels before
giving way to fractional quantum Hall liquids at higher carrier density1,2. Here,
we report the observation of an electron solid with non-collinear spin texture
in monolayer graphene, consistent with solidification of skyrmions3—topological
spin textures characterized by quantized electrical charge4,5. We probe the spin
texture of the solids using a modified Corbino geometry that allows ferromagnetic
magnons to be launched and detected6,7. We find that magnon transport is highly
efficient when one Landau level is filled (ν=1), consistent with quantum Hall
ferromagnetic spin polarization. However, even minimal doping immediately quenches
the magnon signal while leaving the vanishing low-temperature charge conductivity
unchanged. Our results can be understood by the formation of a solid of charged
skyrmions near ν=1, whose non-collinear spin texture leads to rapid magnon decay.
Data near fractional fillings show evidence of several fractional skyrmion solids,
suggesting that graphene hosts a highly tunable landscape of coupled spin and
charge orders.
acknowledgement: We acknowledge discussions with B. Halperin, C. Huang, A. Macdonald
and M. Zalatel. Experimental work at UCSB was supported by the Army Research Office
under awards nos. MURI W911NF-16-1-0361 and W911NF-16-1-0482. K.W. and T.T. acknowledge
support from the Elemental Strategy Initiative conducted by MEXT (Japan) and CREST
(JPMJCR15F3), JST. A.F.Y. acknowledges the support of the David and Lucile Packard
Foundation and and Alfred. P. Sloan Foundation.
article_processing_charge: No
article_type: original
author:
- first_name: H.
full_name: Zhou, H.
last_name: Zhou
- first_name: Hryhoriy
full_name: Polshyn, Hryhoriy
id: edfc7cb1-526e-11ec-b05a-e6ecc27e4e48
last_name: Polshyn
orcid: 0000-0001-8223-8896
- first_name: T.
full_name: Taniguchi, T.
last_name: Taniguchi
- first_name: K.
full_name: Watanabe, K.
last_name: Watanabe
- first_name: A. F.
full_name: Young, A. F.
last_name: Young
citation:
ama: Zhou H, Polshyn H, Taniguchi T, Watanabe K, Young AF. Solids of quantum Hall
skyrmions in graphene. Nature Physics. 2019;16(2):154-158. doi:10.1038/s41567-019-0729-8
apa: Zhou, H., Polshyn, H., Taniguchi, T., Watanabe, K., & Young, A. F. (2019).
Solids of quantum Hall skyrmions in graphene. Nature Physics. Springer
Nature. https://doi.org/10.1038/s41567-019-0729-8
chicago: Zhou, H., Hryhoriy Polshyn, T. Taniguchi, K. Watanabe, and A. F. Young.
“Solids of Quantum Hall Skyrmions in Graphene.” Nature Physics. Springer
Nature, 2019. https://doi.org/10.1038/s41567-019-0729-8.
ieee: H. Zhou, H. Polshyn, T. Taniguchi, K. Watanabe, and A. F. Young, “Solids of
quantum Hall skyrmions in graphene,” Nature Physics, vol. 16, no. 2. Springer
Nature, pp. 154–158, 2019.
ista: Zhou H, Polshyn H, Taniguchi T, Watanabe K, Young AF. 2019. Solids of quantum
Hall skyrmions in graphene. Nature Physics. 16(2), 154–158.
mla: Zhou, H., et al. “Solids of Quantum Hall Skyrmions in Graphene.” Nature
Physics, vol. 16, no. 2, Springer Nature, 2019, pp. 154–58, doi:10.1038/s41567-019-0729-8.
short: H. Zhou, H. Polshyn, T. Taniguchi, K. Watanabe, A.F. Young, Nature Physics
16 (2019) 154–158.
date_created: 2022-01-13T14:45:16Z
date_published: 2019-12-16T00:00:00Z
date_updated: 2022-01-13T15:34:44Z
day: '16'
doi: 10.1038/s41567-019-0729-8
extern: '1'
intvolume: ' 16'
issue: '2'
keyword:
- General Physics and Astronomy
language:
- iso: eng
month: '12'
oa_version: None
page: 154-158
publication: Nature Physics
publication_identifier:
eissn:
- 1745-2481
issn:
- 1745-2473
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Solids of quantum Hall skyrmions in graphene
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 16
year: '2019'
...
---
_id: '10621'
abstract:
- lang: eng
text: Twisted bilayer graphene has recently emerged as a platform for hosting correlated
phenomena. For twist angles near θ ≈ 1.1°, the low-energy electronic structure
of twisted bilayer graphene features isolated bands with a flat dispersion1,2.
Recent experiments have observed a variety of low-temperature phases that appear
to be driven by electron interactions, including insulating states, superconductivity
and magnetism3,4,5,6. Here we report electrical transport measurements up to room
temperature for twist angles varying between 0.75° and 2°. We find that the resistivity,
ρ, scales linearly with temperature, T, over a wide range of T before falling
again owing to interband activation. The T-linear response is much larger than
observed in monolayer graphene for all measured devices, and in particular increases
by more than three orders of magnitude in the range where the flat band exists.
Our results point to the dominant role of electron–phonon scattering in twisted
bilayer graphene, with possible implications for the origin of the observed superconductivity.
acknowledgement: The authors thank S. Das Sarma and F. Wu for sharing their unpublished
theoretical results, and acknowledge further discussions with L. Balents and T.
Senthil. Work at both Columbia and UCSB was funded by the Army Research Office under
award W911NF-17-1-0323. Sample device design and fabrication was partially supported
by DoE Pro-QM EFRC (DE-SC0019443). A.F.Y. and C.R.D. separately acknowledge the
support of the David and Lucile Packard Foundation. K.W. and T.T. acknowledge support
from the Elemental Strategy Initiative conducted by the MEXT, Japan and the CREST
(JPMJCR15F3), JST. A portion of this work was carried out at the KITP, Santa Barbara,
supported by the National Science Foundation under grant number NSF PHY-1748958.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Hryhoriy
full_name: Polshyn, Hryhoriy
id: edfc7cb1-526e-11ec-b05a-e6ecc27e4e48
last_name: Polshyn
orcid: 0000-0001-8223-8896
- first_name: Matthew
full_name: Yankowitz, Matthew
last_name: Yankowitz
- first_name: Shaowen
full_name: Chen, Shaowen
last_name: Chen
- first_name: Yuxuan
full_name: Zhang, Yuxuan
last_name: Zhang
- first_name: K.
full_name: Watanabe, K.
last_name: Watanabe
- first_name: T.
full_name: Taniguchi, T.
last_name: Taniguchi
- first_name: Cory R.
full_name: Dean, Cory R.
last_name: Dean
- first_name: Andrea F.
full_name: Young, Andrea F.
last_name: Young
citation:
ama: Polshyn H, Yankowitz M, Chen S, et al. Large linear-in-temperature resistivity
in twisted bilayer graphene. Nature Physics. 2019;15(10):1011-1016. doi:10.1038/s41567-019-0596-3
apa: Polshyn, H., Yankowitz, M., Chen, S., Zhang, Y., Watanabe, K., Taniguchi, T.,
… Young, A. F. (2019). Large linear-in-temperature resistivity in twisted bilayer
graphene. Nature Physics. Springer Nature. https://doi.org/10.1038/s41567-019-0596-3
chicago: Polshyn, Hryhoriy, Matthew Yankowitz, Shaowen Chen, Yuxuan Zhang, K. Watanabe,
T. Taniguchi, Cory R. Dean, and Andrea F. Young. “Large Linear-in-Temperature
Resistivity in Twisted Bilayer Graphene.” Nature Physics. Springer Nature,
2019. https://doi.org/10.1038/s41567-019-0596-3.
ieee: H. Polshyn et al., “Large linear-in-temperature resistivity in twisted
bilayer graphene,” Nature Physics, vol. 15, no. 10. Springer Nature, pp.
1011–1016, 2019.
ista: Polshyn H, Yankowitz M, Chen S, Zhang Y, Watanabe K, Taniguchi T, Dean CR,
Young AF. 2019. Large linear-in-temperature resistivity in twisted bilayer graphene.
Nature Physics. 15(10), 1011–1016.
mla: Polshyn, Hryhoriy, et al. “Large Linear-in-Temperature Resistivity in Twisted
Bilayer Graphene.” Nature Physics, vol. 15, no. 10, Springer Nature, 2019,
pp. 1011–16, doi:10.1038/s41567-019-0596-3.
short: H. Polshyn, M. Yankowitz, S. Chen, Y. Zhang, K. Watanabe, T. Taniguchi, C.R.
Dean, A.F. Young, Nature Physics 15 (2019) 1011–1016.
date_created: 2022-01-13T15:00:58Z
date_published: 2019-08-05T00:00:00Z
date_updated: 2022-01-20T09:33:38Z
day: '05'
doi: 10.1038/s41567-019-0596-3
extern: '1'
external_id:
arxiv:
- '1902.00763'
intvolume: ' 15'
issue: '10'
keyword:
- general physics and astronomy
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1902.00763
month: '08'
oa: 1
oa_version: Preprint
page: 1011-1016
publication: Nature Physics
publication_identifier:
eissn:
- 1745-2481
issn:
- 1745-2473
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Large linear-in-temperature resistivity in twisted bilayer graphene
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 15
year: '2019'
...
---
_id: '10622'
abstract:
- lang: eng
text: We demonstrate a method for manipulating small ensembles of vortices in multiply
connected superconducting structures. A micron-size magnetic particle attached
to the tip of a silicon cantilever is used to locally apply magnetic flux through
the superconducting structure. By scanning the tip over the surface of the device
and by utilizing the dynamical coupling between the vortices and the cantilever,
a high-resolution spatial map of the different vortex configurations is obtained.
Moving the tip to a particular location in the map stabilizes a distinct multivortex
configuration. Thus, the scanning of the tip over a particular trajectory in space
permits nontrivial operations to be performed, such as braiding of individual
vortices within a larger vortex ensemble—a key capability required by many proposals
for topological quantum computing.
acknowledgement: We are grateful to Nadya Mason, Taylor Hughes, and Alexey Bezryadin
for useful discussions. This work was supported by the DOE Basic Energy Sciences
under DE-SC0012649 and the Department of Physics and the Frederick Seitz Materials
Research Laboratory Central Facilities at the University of Illinois.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Hryhoriy
full_name: Polshyn, Hryhoriy
id: edfc7cb1-526e-11ec-b05a-e6ecc27e4e48
last_name: Polshyn
orcid: 0000-0001-8223-8896
- first_name: Tyler
full_name: Naibert, Tyler
last_name: Naibert
- first_name: Raffi
full_name: Budakian, Raffi
last_name: Budakian
citation:
ama: Polshyn H, Naibert T, Budakian R. Manipulating multivortex states in superconducting
structures. Nano Letters. 2019;19(8):5476-5482. doi:10.1021/acs.nanolett.9b01983
apa: Polshyn, H., Naibert, T., & Budakian, R. (2019). Manipulating multivortex
states in superconducting structures. Nano Letters. American Chemical Society.
https://doi.org/10.1021/acs.nanolett.9b01983
chicago: Polshyn, Hryhoriy, Tyler Naibert, and Raffi Budakian. “Manipulating Multivortex
States in Superconducting Structures.” Nano Letters. American Chemical
Society, 2019. https://doi.org/10.1021/acs.nanolett.9b01983.
ieee: H. Polshyn, T. Naibert, and R. Budakian, “Manipulating multivortex states
in superconducting structures,” Nano Letters, vol. 19, no. 8. American
Chemical Society, pp. 5476–5482, 2019.
ista: Polshyn H, Naibert T, Budakian R. 2019. Manipulating multivortex states in
superconducting structures. Nano Letters. 19(8), 5476–5482.
mla: Polshyn, Hryhoriy, et al. “Manipulating Multivortex States in Superconducting
Structures.” Nano Letters, vol. 19, no. 8, American Chemical Society, 2019,
pp. 5476–82, doi:10.1021/acs.nanolett.9b01983.
short: H. Polshyn, T. Naibert, R. Budakian, Nano Letters 19 (2019) 5476–5482.
date_created: 2022-01-13T15:11:14Z
date_published: 2019-06-27T00:00:00Z
date_updated: 2022-01-13T15:41:24Z
day: '27'
doi: 10.1021/acs.nanolett.9b01983
extern: '1'
external_id:
arxiv:
- '1905.06303'
pmid:
- '31246034'
intvolume: ' 19'
issue: '8'
keyword:
- mechanical engineering
- condensed matter physics
- general materials science
- general chemistry
- bioengineering
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1905.06303
month: '06'
oa: 1
oa_version: Preprint
page: 5476-5482
pmid: 1
publication: Nano Letters
publication_identifier:
eissn:
- 1530-6992
issn:
- 1530-6984
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Manipulating multivortex states in superconducting structures
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 19
year: '2019'
...
---
_id: '10625'
abstract:
- lang: eng
text: The discovery of superconductivity and exotic insulating phases in twisted
bilayer graphene has established this material as a model system of strongly correlated
electrons. To achieve superconductivity, the two layers of graphene need to be
at a very precise angle with respect to each other. Yankowitz et al. now show
that another experimental knob, hydrostatic pressure, can be used to tune the
phase diagram of twisted bilayer graphene (see the Perspective by Feldman). Applying
pressure increased the coupling between the layers, which shifted the superconducting
transition to higher angles and somewhat higher temperatures.
acknowledgement: We thank J. Zhu and H. Zhou for experimental assistance and D. Shahar,
A. Millis, O. Vafek, M. Zaletel, L. Balents, C. Xu, A. Bernevig, L. Fu, M. Koshino,
and P. Moon for helpful discussions.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Matthew
full_name: Yankowitz, Matthew
last_name: Yankowitz
- first_name: Shaowen
full_name: Chen, Shaowen
last_name: Chen
- first_name: Hryhoriy
full_name: Polshyn, Hryhoriy
id: edfc7cb1-526e-11ec-b05a-e6ecc27e4e48
last_name: Polshyn
orcid: 0000-0001-8223-8896
- first_name: Yuxuan
full_name: Zhang, Yuxuan
last_name: Zhang
- first_name: K.
full_name: Watanabe, K.
last_name: Watanabe
- first_name: T.
full_name: Taniguchi, T.
last_name: Taniguchi
- first_name: David
full_name: Graf, David
last_name: Graf
- first_name: Andrea F.
full_name: Young, Andrea F.
last_name: Young
- first_name: Cory R.
full_name: Dean, Cory R.
last_name: Dean
citation:
ama: Yankowitz M, Chen S, Polshyn H, et al. Tuning superconductivity in twisted
bilayer graphene. Science. 2019;363(6431):1059-1064. doi:10.1126/science.aav1910
apa: Yankowitz, M., Chen, S., Polshyn, H., Zhang, Y., Watanabe, K., Taniguchi, T.,
… Dean, C. R. (2019). Tuning superconductivity in twisted bilayer graphene. Science.
American Association for the Advancement of Science (AAAS). https://doi.org/10.1126/science.aav1910
chicago: Yankowitz, Matthew, Shaowen Chen, Hryhoriy Polshyn, Yuxuan Zhang, K. Watanabe,
T. Taniguchi, David Graf, Andrea F. Young, and Cory R. Dean. “Tuning Superconductivity
in Twisted Bilayer Graphene.” Science. American Association for the Advancement
of Science (AAAS), 2019. https://doi.org/10.1126/science.aav1910.
ieee: M. Yankowitz et al., “Tuning superconductivity in twisted bilayer graphene,”
Science, vol. 363, no. 6431. American Association for the Advancement of
Science (AAAS), pp. 1059–1064, 2019.
ista: Yankowitz M, Chen S, Polshyn H, Zhang Y, Watanabe K, Taniguchi T, Graf D,
Young AF, Dean CR. 2019. Tuning superconductivity in twisted bilayer graphene.
Science. 363(6431), 1059–1064.
mla: Yankowitz, Matthew, et al. “Tuning Superconductivity in Twisted Bilayer Graphene.”
Science, vol. 363, no. 6431, American Association for the Advancement of
Science (AAAS), 2019, pp. 1059–64, doi:10.1126/science.aav1910.
short: M. Yankowitz, S. Chen, H. Polshyn, Y. Zhang, K. Watanabe, T. Taniguchi, D.
Graf, A.F. Young, C.R. Dean, Science 363 (2019) 1059–1064.
date_created: 2022-01-14T12:14:58Z
date_published: 2019-01-24T00:00:00Z
date_updated: 2022-01-14T13:48:32Z
day: '24'
doi: 10.1126/science.aav1910
extern: '1'
external_id:
arxiv:
- '1808.07865'
pmid:
- '30679385 '
intvolume: ' 363'
issue: '6431'
keyword:
- multidisciplinary
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1808.07865
month: '01'
oa: 1
oa_version: Preprint
page: 1059-1064
pmid: 1
publication: Science
publication_identifier:
eissn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science (AAAS)
quality_controlled: '1'
scopus_import: '1'
status: public
title: Tuning superconductivity in twisted bilayer graphene
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 363
year: '2019'
...