---
_id: '7231'
abstract:
- lang: eng
text: Piecewise Barrier Tubes (PBT) is a new technique for flowpipe overapproximation
for nonlinear systems with polynomial dynamics, which leverages a combination
of barrier certificates. PBT has advantages over traditional time-step based methods
in dealing with those nonlinear dynamical systems in which there is a large difference
in speed between trajectories, producing an overapproximation that is time independent.
However, the existing approach for PBT is not efficient due to the application
of interval methods for enclosure-box computation, and it can only deal with continuous
dynamical systems without uncertainty. In this paper, we extend the approach with
the ability to handle both continuous and hybrid dynamical systems with uncertainty
that can reside in parameters and/or noise. We also improve the efficiency of
the method significantly, by avoiding the use of interval-based methods for the
enclosure-box computation without loosing soundness. We have developed a C++ prototype
implementing the proposed approach and we evaluate it on several benchmarks. The
experiments show that our approach is more efficient and precise than other methods
in the literature.
alternative_title:
- LNCS
article_processing_charge: No
arxiv: 1
author:
- first_name: Hui
full_name: Kong, Hui
id: 3BDE25AA-F248-11E8-B48F-1D18A9856A87
last_name: Kong
orcid: 0000-0002-3066-6941
- first_name: Ezio
full_name: Bartocci, Ezio
last_name: Bartocci
- first_name: Yu
full_name: Jiang, Yu
last_name: Jiang
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
citation:
ama: 'Kong H, Bartocci E, Jiang Y, Henzinger TA. Piecewise robust barrier tubes
for nonlinear hybrid systems with uncertainty. In: 17th International Conference
on Formal Modeling and Analysis of Timed Systems. Vol 11750. Springer Nature;
2019:123-141. doi:10.1007/978-3-030-29662-9_8'
apa: 'Kong, H., Bartocci, E., Jiang, Y., & Henzinger, T. A. (2019). Piecewise
robust barrier tubes for nonlinear hybrid systems with uncertainty. In 17th
International Conference on Formal Modeling and Analysis of Timed Systems
(Vol. 11750, pp. 123–141). Amsterdam, The Netherlands: Springer Nature. https://doi.org/10.1007/978-3-030-29662-9_8'
chicago: Kong, Hui, Ezio Bartocci, Yu Jiang, and Thomas A Henzinger. “Piecewise
Robust Barrier Tubes for Nonlinear Hybrid Systems with Uncertainty.” In 17th
International Conference on Formal Modeling and Analysis of Timed Systems,
11750:123–41. Springer Nature, 2019. https://doi.org/10.1007/978-3-030-29662-9_8.
ieee: H. Kong, E. Bartocci, Y. Jiang, and T. A. Henzinger, “Piecewise robust barrier
tubes for nonlinear hybrid systems with uncertainty,” in 17th International
Conference on Formal Modeling and Analysis of Timed Systems, Amsterdam, The
Netherlands, 2019, vol. 11750, pp. 123–141.
ista: 'Kong H, Bartocci E, Jiang Y, Henzinger TA. 2019. Piecewise robust barrier
tubes for nonlinear hybrid systems with uncertainty. 17th International Conference
on Formal Modeling and Analysis of Timed Systems. FORMATS: Formal Modeling and
Analysis of Timed Systems, LNCS, vol. 11750, 123–141.'
mla: Kong, Hui, et al. “Piecewise Robust Barrier Tubes for Nonlinear Hybrid Systems
with Uncertainty.” 17th International Conference on Formal Modeling and Analysis
of Timed Systems, vol. 11750, Springer Nature, 2019, pp. 123–41, doi:10.1007/978-3-030-29662-9_8.
short: H. Kong, E. Bartocci, Y. Jiang, T.A. Henzinger, in:, 17th International Conference
on Formal Modeling and Analysis of Timed Systems, Springer Nature, 2019, pp. 123–141.
conference:
end_date: 2019-08-29
location: Amsterdam, The Netherlands
name: 'FORMATS: Formal Modeling and Analysis of Timed Systems'
start_date: 2019-08-27
date_created: 2020-01-05T23:00:47Z
date_published: 2019-08-13T00:00:00Z
date_updated: 2023-09-06T14:55:15Z
day: '13'
department:
- _id: ToHe
doi: 10.1007/978-3-030-29662-9_8
external_id:
arxiv:
- '1907.11514'
isi:
- '000611677700008'
intvolume: ' 11750'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1907.11514
month: '08'
oa: 1
oa_version: Preprint
page: 123-141
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11407
name: Game Theory
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z211
name: The Wittgenstein Prize
publication: 17th International Conference on Formal Modeling and Analysis of Timed
Systems
publication_identifier:
eissn:
- 1611-3349
isbn:
- 978-3-0302-9661-2
issn:
- 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Piecewise robust barrier tubes for nonlinear hybrid systems with uncertainty
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 11750
year: '2019'
...
---
_id: '7232'
abstract:
- lang: eng
text: 'We present Mixed-time Signal Temporal Logic (STL−MX), a specification formalism
which extends STL by capturing the discrete/ continuous time duality found in
many cyber-physical systems (CPS), as well as mixed-signal electronic designs.
In STL−MX, properties of components with continuous dynamics are expressed in
STL, while specifications of components with discrete dynamics are written in
LTL. To combine the two layers, we evaluate formulas on two traces, discrete-
and continuous-time, and introduce two interface operators that map signals, properties
and their satisfaction signals across the two time domains. We show that STL-mx
has the expressive power of STL supplemented with an implicit T-periodic clock
signal. We develop and implement an algorithm for monitoring STL-mx formulas and
illustrate the approach using a mixed-signal example. '
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Thomas
full_name: Ferrere, Thomas
id: 40960E6E-F248-11E8-B48F-1D18A9856A87
last_name: Ferrere
orcid: 0000-0001-5199-3143
- first_name: Oded
full_name: Maler, Oded
last_name: Maler
- first_name: Dejan
full_name: Nickovic, Dejan
id: 41BCEE5C-F248-11E8-B48F-1D18A9856A87
last_name: Nickovic
citation:
ama: 'Ferrere T, Maler O, Nickovic D. Mixed-time signal temporal logic. In: 17th
International Conference on Formal Modeling and Analysis of Timed Systems.
Vol 11750. Springer Nature; 2019:59-75. doi:10.1007/978-3-030-29662-9_4'
apa: 'Ferrere, T., Maler, O., & Nickovic, D. (2019). Mixed-time signal temporal
logic. In 17th International Conference on Formal Modeling and Analysis of
Timed Systems (Vol. 11750, pp. 59–75). Amsterdam, The Netherlands: Springer
Nature. https://doi.org/10.1007/978-3-030-29662-9_4'
chicago: Ferrere, Thomas, Oded Maler, and Dejan Nickovic. “Mixed-Time Signal Temporal
Logic.” In 17th International Conference on Formal Modeling and Analysis of
Timed Systems, 11750:59–75. Springer Nature, 2019. https://doi.org/10.1007/978-3-030-29662-9_4.
ieee: T. Ferrere, O. Maler, and D. Nickovic, “Mixed-time signal temporal logic,”
in 17th International Conference on Formal Modeling and Analysis of Timed Systems,
Amsterdam, The Netherlands, 2019, vol. 11750, pp. 59–75.
ista: 'Ferrere T, Maler O, Nickovic D. 2019. Mixed-time signal temporal logic. 17th
International Conference on Formal Modeling and Analysis of Timed Systems. FORMATS:
Formal Modeling and Anaysis of Timed Systems, LNCS, vol. 11750, 59–75.'
mla: Ferrere, Thomas, et al. “Mixed-Time Signal Temporal Logic.” 17th International
Conference on Formal Modeling and Analysis of Timed Systems, vol. 11750, Springer
Nature, 2019, pp. 59–75, doi:10.1007/978-3-030-29662-9_4.
short: T. Ferrere, O. Maler, D. Nickovic, in:, 17th International Conference on
Formal Modeling and Analysis of Timed Systems, Springer Nature, 2019, pp. 59–75.
conference:
end_date: 2019-08-29
location: Amsterdam, The Netherlands
name: 'FORMATS: Formal Modeling and Anaysis of Timed Systems'
start_date: 2019-08-27
date_created: 2020-01-05T23:00:48Z
date_published: 2019-08-13T00:00:00Z
date_updated: 2023-09-06T14:57:17Z
day: '13'
department:
- _id: ToHe
doi: 10.1007/978-3-030-29662-9_4
external_id:
isi:
- '000611677700004'
intvolume: ' 11750'
isi: 1
language:
- iso: eng
month: '08'
oa_version: None
page: 59-75
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z211
name: The Wittgenstein Prize
publication: 17th International Conference on Formal Modeling and Analysis of Timed
Systems
publication_identifier:
eissn:
- 1611-3349
isbn:
- 978-3-0302-9661-2
issn:
- 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Mixed-time signal temporal logic
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 11750
year: '2019'
...
---
_id: '7233'
abstract:
- lang: eng
text: We demonstrate electro-optic frequency comb generation using a doubly resonant
system comprising a whispering gallery mode disk resonator made of lithium niobate
mounted inside a three dimensional copper cavity. We observe 180 sidebands centred
at 1550 nm.
article_number: NM2A.5
article_processing_charge: No
author:
- first_name: Alfredo R
full_name: Rueda Sanchez, Alfredo R
id: 3B82B0F8-F248-11E8-B48F-1D18A9856A87
last_name: Rueda Sanchez
orcid: 0000-0001-6249-5860
- first_name: Florian
full_name: Sedlmeir, Florian
last_name: Sedlmeir
- first_name: Gerd
full_name: Leuchs, Gerd
last_name: Leuchs
- first_name: Madhuri
full_name: Kumari, Madhuri
last_name: Kumari
- first_name: Harald G.L.
full_name: Schwefel, Harald G.L.
last_name: Schwefel
citation:
ama: 'Rueda Sanchez AR, Sedlmeir F, Leuchs G, Kumari M, Schwefel HGL. Resonant electro-optic
frequency comb generation in lithium niobate disk resonator inside a microwave
cavity. In: Nonlinear Optics, OSA Technical Digest. Optica Publishing
Group; 2019. doi:10.1364/NLO.2019.NM2A.5'
apa: 'Rueda Sanchez, A. R., Sedlmeir, F., Leuchs, G., Kumari, M., & Schwefel,
H. G. L. (2019). Resonant electro-optic frequency comb generation in lithium niobate
disk resonator inside a microwave cavity. In Nonlinear Optics, OSA Technical
Digest. Waikoloa Beach, Hawaii (HI), United States: Optica Publishing Group.
https://doi.org/10.1364/NLO.2019.NM2A.5'
chicago: Rueda Sanchez, Alfredo R, Florian Sedlmeir, Gerd Leuchs, Madhuri Kumari,
and Harald G.L. Schwefel. “Resonant Electro-Optic Frequency Comb Generation in
Lithium Niobate Disk Resonator inside a Microwave Cavity.” In Nonlinear Optics,
OSA Technical Digest. Optica Publishing Group, 2019. https://doi.org/10.1364/NLO.2019.NM2A.5.
ieee: A. R. Rueda Sanchez, F. Sedlmeir, G. Leuchs, M. Kumari, and H. G. L. Schwefel,
“Resonant electro-optic frequency comb generation in lithium niobate disk resonator
inside a microwave cavity,” in Nonlinear Optics, OSA Technical Digest,
Waikoloa Beach, Hawaii (HI), United States, 2019.
ista: 'Rueda Sanchez AR, Sedlmeir F, Leuchs G, Kumari M, Schwefel HGL. 2019. Resonant
electro-optic frequency comb generation in lithium niobate disk resonator inside
a microwave cavity. Nonlinear Optics, OSA Technical Digest. NLO: Nonlinear Optics,
NM2A.5.'
mla: Rueda Sanchez, Alfredo R., et al. “Resonant Electro-Optic Frequency Comb Generation
in Lithium Niobate Disk Resonator inside a Microwave Cavity.” Nonlinear Optics,
OSA Technical Digest, NM2A.5, Optica Publishing Group, 2019, doi:10.1364/NLO.2019.NM2A.5.
short: A.R. Rueda Sanchez, F. Sedlmeir, G. Leuchs, M. Kumari, H.G.L. Schwefel, in:,
Nonlinear Optics, OSA Technical Digest, Optica Publishing Group, 2019.
conference:
end_date: 2019-07-19
location: Waikoloa Beach, Hawaii (HI), United States
name: 'NLO: Nonlinear Optics'
start_date: 2019-07-15
date_created: 2020-01-05T23:00:48Z
date_published: 2019-07-15T00:00:00Z
date_updated: 2023-10-17T12:14:46Z
day: '15'
department:
- _id: JoFi
doi: 10.1364/NLO.2019.NM2A.5
language:
- iso: eng
month: '07'
oa_version: None
publication: Nonlinear Optics, OSA Technical Digest
publication_identifier:
isbn:
- '9781557528209'
publication_status: published
publisher: Optica Publishing Group
quality_controlled: '1'
scopus_import: '1'
status: public
title: Resonant electro-optic frequency comb generation in lithium niobate disk resonator
inside a microwave cavity
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2019'
...
---
_id: '7275'
abstract:
- lang: eng
text: Aprotic alkali metal–oxygen batteries require reversible formation of metal
superoxide or peroxide on cycling. Severe parasitic reactions cause poor rechargeability,
efficiency, and cycle life and have been shown to be caused by singlet oxygen
(1O2) that forms at all stages of cycling. However, its formation mechanism remains
unclear. We show that disproportionation of superoxide, the product or intermediate
on discharge and charge, to peroxide and oxygen is responsible for 1O2 formation.
While the overall reaction is driven by the stability of peroxide and thus favored
by stronger Lewis acidic cations such as Li+, the 1O2 fraction is enhanced by
weak Lewis acids such as organic cations. Concurrently, the metal peroxide yield
drops with increasing 1O2. The results explain a major parasitic pathway during
cell cycling and the growing severity in K–, Na–, and Li–O2 cells based on the
growing propensity for disproportionation. High capacities and rates with peroxides
are now realized to require solution processes, which form peroxide or release
O2via disproportionation. The results therefore establish the central dilemma
that disproportionation is required for high capacity but also responsible for
irreversible reactions. Highly reversible cell operation requires hence finding
reaction routes that avoid disproportionation.
article_processing_charge: No
article_type: original
author:
- first_name: Eléonore
full_name: Mourad, Eléonore
last_name: Mourad
- first_name: Yann K.
full_name: Petit, Yann K.
last_name: Petit
- first_name: Riccardo
full_name: Spezia, Riccardo
last_name: Spezia
- first_name: Aleksej
full_name: Samojlov, Aleksej
last_name: Samojlov
- first_name: Francesco F.
full_name: Summa, Francesco F.
last_name: Summa
- first_name: Christian
full_name: Prehal, Christian
last_name: Prehal
- first_name: Christian
full_name: Leypold, Christian
last_name: Leypold
- first_name: Nika
full_name: Mahne, Nika
last_name: Mahne
- first_name: Christian
full_name: Slugovc, Christian
last_name: Slugovc
- first_name: Olivier
full_name: Fontaine, Olivier
last_name: Fontaine
- first_name: Sergio
full_name: Brutti, Sergio
last_name: Brutti
- first_name: Stefan Alexander
full_name: Freunberger, Stefan Alexander
id: A8CA28E6-CE23-11E9-AD2D-EC27E6697425
last_name: Freunberger
orcid: 0000-0003-2902-5319
citation:
ama: Mourad E, Petit YK, Spezia R, et al. Singlet oxygen from cation driven superoxide
disproportionation and consequences for aprotic metal–O2 batteries. Energy
& Environmental Science. 2019;12(8):2559-2568. doi:10.1039/c9ee01453e
apa: Mourad, E., Petit, Y. K., Spezia, R., Samojlov, A., Summa, F. F., Prehal, C.,
… Freunberger, S. A. (2019). Singlet oxygen from cation driven superoxide disproportionation
and consequences for aprotic metal–O2 batteries. Energy & Environmental
Science. RSC. https://doi.org/10.1039/c9ee01453e
chicago: Mourad, Eléonore, Yann K. Petit, Riccardo Spezia, Aleksej Samojlov, Francesco
F. Summa, Christian Prehal, Christian Leypold, et al. “Singlet Oxygen from Cation
Driven Superoxide Disproportionation and Consequences for Aprotic Metal–O2 Batteries.”
Energy & Environmental Science. RSC, 2019. https://doi.org/10.1039/c9ee01453e.
ieee: E. Mourad et al., “Singlet oxygen from cation driven superoxide disproportionation
and consequences for aprotic metal–O2 batteries,” Energy & Environmental
Science, vol. 12, no. 8. RSC, pp. 2559–2568, 2019.
ista: Mourad E, Petit YK, Spezia R, Samojlov A, Summa FF, Prehal C, Leypold C, Mahne
N, Slugovc C, Fontaine O, Brutti S, Freunberger SA. 2019. Singlet oxygen from
cation driven superoxide disproportionation and consequences for aprotic metal–O2
batteries. Energy & Environmental Science. 12(8), 2559–2568.
mla: Mourad, Eléonore, et al. “Singlet Oxygen from Cation Driven Superoxide Disproportionation
and Consequences for Aprotic Metal–O2 Batteries.” Energy & Environmental
Science, vol. 12, no. 8, RSC, 2019, pp. 2559–68, doi:10.1039/c9ee01453e.
short: E. Mourad, Y.K. Petit, R. Spezia, A. Samojlov, F.F. Summa, C. Prehal, C.
Leypold, N. Mahne, C. Slugovc, O. Fontaine, S. Brutti, S.A. Freunberger, Energy
& Environmental Science 12 (2019) 2559–2568.
date_created: 2020-01-15T07:18:04Z
date_published: 2019-08-01T00:00:00Z
date_updated: 2021-01-12T08:12:41Z
day: '01'
ddc:
- '530'
- '541'
- '540'
doi: 10.1039/c9ee01453e
extern: '1'
file:
- access_level: open_access
checksum: 94d4cfb2ab0b4c90ef76a7f3cc811feb
content_type: application/pdf
creator: dernst
date_created: 2020-01-30T16:11:05Z
date_updated: 2020-07-14T12:47:55Z
file_id: '7424'
file_name: 2019_EnergyEnvironScienc_Mourad.pdf
file_size: 2888027
relation: main_file
file_date_updated: 2020-07-14T12:47:55Z
has_accepted_license: '1'
intvolume: ' 12'
issue: '8'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: 2559-2568
publication: Energy & Environmental Science
publication_identifier:
issn:
- 1754-5692
- 1754-5706
publication_status: published
publisher: RSC
quality_controlled: '1'
status: public
title: Singlet oxygen from cation driven superoxide disproportionation and consequences
for aprotic metal–O2 batteries
tmp:
image: /images/cc_by_nc.png
legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
short: CC BY-NC (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 12
year: '2019'
...
---
_id: '7276'
abstract:
- lang: eng
text: Singlet oxygen (1O2) causes a major fraction of the parasitic chemistry during
the cycling of non‐aqueous alkali metal‐O2 batteries and also contributes to interfacial
reactivity of transition‐metal oxide intercalation compounds. We introduce DABCOnium,
the mono alkylated form of 1,4‐diazabicyclo[2.2.2]octane (DABCO), as an efficient
1O2 quencher with an unusually high oxidative stability of ca. 4.2 V vs. Li/Li+.
Previous quenchers are strongly Lewis basic amines with too low oxidative stability.
DABCOnium is an ionic liquid, non‐volatile, highly soluble in the electrolyte,
stable against superoxide and peroxide, and compatible with lithium metal. The
electrochemical stability covers the required range for metal–O2 batteries and
greatly reduces 1O2 related parasitic chemistry as demonstrated for the Li–O2
cell.
article_processing_charge: No
article_type: original
author:
- first_name: Yann K.
full_name: Petit, Yann K.
last_name: Petit
- first_name: Christian
full_name: Leypold, Christian
last_name: Leypold
- first_name: Nika
full_name: Mahne, Nika
last_name: Mahne
- first_name: Eléonore
full_name: Mourad, Eléonore
last_name: Mourad
- first_name: Lukas
full_name: Schafzahl, Lukas
last_name: Schafzahl
- first_name: Christian
full_name: Slugovc, Christian
last_name: Slugovc
- first_name: Sergey M.
full_name: Borisov, Sergey M.
last_name: Borisov
- first_name: Stefan Alexander
full_name: Freunberger, Stefan Alexander
id: A8CA28E6-CE23-11E9-AD2D-EC27E6697425
last_name: Freunberger
orcid: 0000-0003-2902-5319
citation:
ama: 'Petit YK, Leypold C, Mahne N, et al. DABCOnium: An efficient and high-voltage
stable singlet oxygen quencher for metal-O2 cells. Angewandte Chemie International
Edition. 2019;58(20):6535-6539. doi:10.1002/anie.201901869'
apa: 'Petit, Y. K., Leypold, C., Mahne, N., Mourad, E., Schafzahl, L., Slugovc,
C., … Freunberger, S. A. (2019). DABCOnium: An efficient and high-voltage stable
singlet oxygen quencher for metal-O2 cells. Angewandte Chemie International
Edition. Wiley. https://doi.org/10.1002/anie.201901869'
chicago: 'Petit, Yann K., Christian Leypold, Nika Mahne, Eléonore Mourad, Lukas
Schafzahl, Christian Slugovc, Sergey M. Borisov, and Stefan Alexander Freunberger.
“DABCOnium: An Efficient and High-Voltage Stable Singlet Oxygen Quencher for Metal-O2
Cells.” Angewandte Chemie International Edition. Wiley, 2019. https://doi.org/10.1002/anie.201901869.'
ieee: 'Y. K. Petit et al., “DABCOnium: An efficient and high-voltage stable
singlet oxygen quencher for metal-O2 cells,” Angewandte Chemie International
Edition, vol. 58, no. 20. Wiley, pp. 6535–6539, 2019.'
ista: 'Petit YK, Leypold C, Mahne N, Mourad E, Schafzahl L, Slugovc C, Borisov SM,
Freunberger SA. 2019. DABCOnium: An efficient and high-voltage stable singlet
oxygen quencher for metal-O2 cells. Angewandte Chemie International Edition. 58(20),
6535–6539.'
mla: 'Petit, Yann K., et al. “DABCOnium: An Efficient and High-Voltage Stable Singlet
Oxygen Quencher for Metal-O2 Cells.” Angewandte Chemie International Edition,
vol. 58, no. 20, Wiley, 2019, pp. 6535–39, doi:10.1002/anie.201901869.'
short: Y.K. Petit, C. Leypold, N. Mahne, E. Mourad, L. Schafzahl, C. Slugovc, S.M.
Borisov, S.A. Freunberger, Angewandte Chemie International Edition 58 (2019) 6535–6539.
date_created: 2020-01-15T07:19:27Z
date_published: 2019-05-13T00:00:00Z
date_updated: 2021-01-12T08:12:42Z
day: '13'
ddc:
- '540'
doi: 10.1002/anie.201901869
extern: '1'
file:
- access_level: open_access
checksum: 9620b6a511a910d7abe1f26c42dc7f83
content_type: application/pdf
creator: dernst
date_created: 2020-01-22T16:16:54Z
date_updated: 2020-07-14T12:47:55Z
file_id: '7356'
file_name: 2019_AngewChemie_Petit.pdf
file_size: 952737
relation: main_file
file_date_updated: 2020-07-14T12:47:55Z
has_accepted_license: '1'
intvolume: ' 58'
issue: '20'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: 6535-6539
publication: Angewandte Chemie International Edition
publication_identifier:
issn:
- 1433-7851
publication_status: published
publisher: Wiley
quality_controlled: '1'
status: public
title: 'DABCOnium: An efficient and high-voltage stable singlet oxygen quencher for
metal-O2 cells'
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 58
year: '2019'
...
---
_id: '7280'
abstract:
- lang: eng
text: Non-aqueous lithium-oxygen batteries cycle by forming lithium peroxide during
discharge and oxidizing it during recharge. The significant problem of oxidizing
the solid insulating lithium peroxide can greatly be facilitated by incorporating
redox mediators that shuttle electron-holes between the porous substrate and lithium
peroxide. Redox mediator stability is thus key for energy efficiency, reversibility,
and cycle life. However, the gradual deactivation of redox mediators during repeated
cycling has not conclusively been explained. Here, we show that organic redox
mediators are predominantly decomposed by singlet oxygen that forms during cycling.
Their reaction with superoxide, previously assumed to mainly trigger their degradation,
peroxide, and dioxygen, is orders of magnitude slower in comparison. The reduced
form of the mediator is markedly more reactive towards singlet oxygen than the
oxidized form, from which we derive reaction mechanisms supported by density functional
theory calculations. Redox mediators must thus be designed for stability against
singlet oxygen.
article_number: '1380'
article_processing_charge: No
article_type: original
author:
- first_name: Won-Jin
full_name: Kwak, Won-Jin
last_name: Kwak
- first_name: Hun
full_name: Kim, Hun
last_name: Kim
- first_name: Yann K.
full_name: Petit, Yann K.
last_name: Petit
- first_name: Christian
full_name: Leypold, Christian
last_name: Leypold
- first_name: Trung Thien
full_name: Nguyen, Trung Thien
last_name: Nguyen
- first_name: Nika
full_name: Mahne, Nika
last_name: Mahne
- first_name: Paul
full_name: Redfern, Paul
last_name: Redfern
- first_name: Larry A.
full_name: Curtiss, Larry A.
last_name: Curtiss
- first_name: Hun-Gi
full_name: Jung, Hun-Gi
last_name: Jung
- first_name: Sergey M.
full_name: Borisov, Sergey M.
last_name: Borisov
- first_name: Stefan Alexander
full_name: Freunberger, Stefan Alexander
id: A8CA28E6-CE23-11E9-AD2D-EC27E6697425
last_name: Freunberger
orcid: 0000-0003-2902-5319
- first_name: Yang-Kook
full_name: Sun, Yang-Kook
last_name: Sun
citation:
ama: Kwak W-J, Kim H, Petit YK, et al. Deactivation of redox mediators in lithium-oxygen
batteries by singlet oxygen. Nature Communications. 2019;10. doi:10.1038/s41467-019-09399-0
apa: Kwak, W.-J., Kim, H., Petit, Y. K., Leypold, C., Nguyen, T. T., Mahne, N.,
… Sun, Y.-K. (2019). Deactivation of redox mediators in lithium-oxygen batteries
by singlet oxygen. Nature Communications. Springer Nature. https://doi.org/10.1038/s41467-019-09399-0
chicago: Kwak, Won-Jin, Hun Kim, Yann K. Petit, Christian Leypold, Trung Thien Nguyen,
Nika Mahne, Paul Redfern, et al. “Deactivation of Redox Mediators in Lithium-Oxygen
Batteries by Singlet Oxygen.” Nature Communications. Springer Nature, 2019.
https://doi.org/10.1038/s41467-019-09399-0.
ieee: W.-J. Kwak et al., “Deactivation of redox mediators in lithium-oxygen
batteries by singlet oxygen,” Nature Communications, vol. 10. Springer
Nature, 2019.
ista: Kwak W-J, Kim H, Petit YK, Leypold C, Nguyen TT, Mahne N, Redfern P, Curtiss
LA, Jung H-G, Borisov SM, Freunberger SA, Sun Y-K. 2019. Deactivation of redox
mediators in lithium-oxygen batteries by singlet oxygen. Nature Communications.
10, 1380.
mla: Kwak, Won-Jin, et al. “Deactivation of Redox Mediators in Lithium-Oxygen Batteries
by Singlet Oxygen.” Nature Communications, vol. 10, 1380, Springer Nature,
2019, doi:10.1038/s41467-019-09399-0.
short: W.-J. Kwak, H. Kim, Y.K. Petit, C. Leypold, T.T. Nguyen, N. Mahne, P. Redfern,
L.A. Curtiss, H.-G. Jung, S.M. Borisov, S.A. Freunberger, Y.-K. Sun, Nature Communications
10 (2019).
date_created: 2020-01-15T12:12:26Z
date_published: 2019-03-26T00:00:00Z
date_updated: 2021-01-12T08:12:44Z
day: '26'
ddc:
- '540'
doi: 10.1038/s41467-019-09399-0
extern: '1'
file:
- access_level: open_access
checksum: 123dd33e7f26761c82c74e10811a1e4d
content_type: application/pdf
creator: dernst
date_created: 2020-01-22T15:58:54Z
date_updated: 2020-07-14T12:47:55Z
file_id: '7355'
file_name: 2019_NatureComm_Kwak.pdf
file_size: 1003676
relation: main_file
file_date_updated: 2020-07-14T12:47:55Z
has_accepted_license: '1'
intvolume: ' 10'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
publication: Nature Communications
publication_identifier:
issn:
- 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Deactivation of redox mediators in lithium-oxygen batteries by singlet oxygen
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 10
year: '2019'
...
---
_id: '7281'
abstract:
- lang: eng
text: Li–O2 batteries are plagued by side reactions that cause poor rechargeability
and efficiency. These reactions were recently revealed to be predominantly caused
by singlet oxygen, which can be neutralized by chemical traps or physical quenchers.
However, traps are irreversibly consumed and thus only active for a limited time,
and so far identified quenchers lack oxidative stability to be suitable for typically
required recharge potentials. Thus, reducing the charge potential within the stability
limit of the quencher and/or finding more stable quenchers is required. Here,
we show that dimethylphenazine as a redox mediator decreases the charge potential
well within the stability limit of the quencher 1,4-diazabicyclo[2.2.2]octane.
The quencher can thus mitigate the parasitic reactions without being oxidatively
decomposed. At the same time the quencher protects the redox mediator from singlet
oxygen attack. The mutual conservation of the redox mediator and the quencher
is rational for stable and effective Li–O2 batteries.
article_processing_charge: No
article_type: original
author:
- first_name: Won-Jin
full_name: Kwak, Won-Jin
last_name: Kwak
- first_name: Stefan Alexander
full_name: Freunberger, Stefan Alexander
id: A8CA28E6-CE23-11E9-AD2D-EC27E6697425
last_name: Freunberger
orcid: 0000-0003-2902-5319
- first_name: Hun
full_name: Kim, Hun
last_name: Kim
- first_name: Jiwon
full_name: Park, Jiwon
last_name: Park
- first_name: Trung Thien
full_name: Nguyen, Trung Thien
last_name: Nguyen
- first_name: Hun-Gi
full_name: Jung, Hun-Gi
last_name: Jung
- first_name: Hye Ryung
full_name: Byon, Hye Ryung
last_name: Byon
- first_name: Yang-Kook
full_name: Sun, Yang-Kook
last_name: Sun
citation:
ama: Kwak W-J, Freunberger SA, Kim H, et al. Mutual conservation of redox mediator
and singlet oxygen quencher in Lithium–Oxygen batteries. ACS Catalysis.
2019;9(11):9914-9922. doi:10.1021/acscatal.9b01337
apa: Kwak, W.-J., Freunberger, S. A., Kim, H., Park, J., Nguyen, T. T., Jung, H.-G.,
… Sun, Y.-K. (2019). Mutual conservation of redox mediator and singlet oxygen
quencher in Lithium–Oxygen batteries. ACS Catalysis. ACS. https://doi.org/10.1021/acscatal.9b01337
chicago: Kwak, Won-Jin, Stefan Alexander Freunberger, Hun Kim, Jiwon Park, Trung
Thien Nguyen, Hun-Gi Jung, Hye Ryung Byon, and Yang-Kook Sun. “Mutual Conservation
of Redox Mediator and Singlet Oxygen Quencher in Lithium–Oxygen Batteries.” ACS
Catalysis. ACS, 2019. https://doi.org/10.1021/acscatal.9b01337.
ieee: W.-J. Kwak et al., “Mutual conservation of redox mediator and singlet
oxygen quencher in Lithium–Oxygen batteries,” ACS Catalysis, vol. 9, no.
11. ACS, pp. 9914–9922, 2019.
ista: Kwak W-J, Freunberger SA, Kim H, Park J, Nguyen TT, Jung H-G, Byon HR, Sun
Y-K. 2019. Mutual conservation of redox mediator and singlet oxygen quencher in
Lithium–Oxygen batteries. ACS Catalysis. 9(11), 9914–9922.
mla: Kwak, Won-Jin, et al. “Mutual Conservation of Redox Mediator and Singlet Oxygen
Quencher in Lithium–Oxygen Batteries.” ACS Catalysis, vol. 9, no. 11, ACS,
2019, pp. 9914–22, doi:10.1021/acscatal.9b01337.
short: W.-J. Kwak, S.A. Freunberger, H. Kim, J. Park, T.T. Nguyen, H.-G. Jung, H.R.
Byon, Y.-K. Sun, ACS Catalysis 9 (2019) 9914–9922.
date_created: 2020-01-15T12:12:40Z
date_published: 2019-11-01T00:00:00Z
date_updated: 2021-01-12T08:12:44Z
day: '01'
ddc:
- '540'
doi: 10.1021/acscatal.9b01337
extern: '1'
file:
- access_level: open_access
checksum: bbaebfe5ff0bcab6235821ba3460b7de
content_type: application/pdf
creator: sfreunbe
date_created: 2020-06-29T15:19:30Z
date_updated: 2020-07-14T12:47:55Z
file_id: '8053'
file_name: Revised Manuscript.pdf
file_size: 1199086
relation: main_file
file_date_updated: 2020-07-14T12:47:55Z
has_accepted_license: '1'
intvolume: ' 9'
issue: '11'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Submitted Version
page: 9914-9922
publication: ACS Catalysis
publication_identifier:
issn:
- 2155-5435
publication_status: published
publisher: ACS
quality_controlled: '1'
status: public
title: Mutual conservation of redox mediator and singlet oxygen quencher in Lithium–Oxygen
batteries
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9
year: '2019'
...
---
_id: '7282'
abstract:
- lang: eng
text: Interphases that form on the anode surface of lithium-ion batteries are critical
for performance and lifetime, but are poorly understood. Now, a decade-old misconception
regarding a main component of the interphase has been revealed, which could potentially
lead to improved devices.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Stefan Alexander
full_name: Freunberger, Stefan Alexander
id: A8CA28E6-CE23-11E9-AD2D-EC27E6697425
last_name: Freunberger
orcid: 0000-0003-2902-5319
citation:
ama: Freunberger SA. Interphase identity crisis. Nature Chemistry. 2019;11(9):761-763.
doi:10.1038/s41557-019-0311-0
apa: Freunberger, S. A. (2019). Interphase identity crisis. Nature Chemistry.
Springer Nature. https://doi.org/10.1038/s41557-019-0311-0
chicago: Freunberger, Stefan Alexander. “Interphase Identity Crisis.” Nature
Chemistry. Springer Nature, 2019. https://doi.org/10.1038/s41557-019-0311-0.
ieee: S. A. Freunberger, “Interphase identity crisis,” Nature Chemistry,
vol. 11, no. 9. Springer Nature, pp. 761–763, 2019.
ista: Freunberger SA. 2019. Interphase identity crisis. Nature Chemistry. 11(9),
761–763.
mla: Freunberger, Stefan Alexander. “Interphase Identity Crisis.” Nature Chemistry,
vol. 11, no. 9, Springer Nature, 2019, pp. 761–63, doi:10.1038/s41557-019-0311-0.
short: S.A. Freunberger, Nature Chemistry 11 (2019) 761–763.
date_created: 2020-01-15T12:12:53Z
date_published: 2019-08-19T00:00:00Z
date_updated: 2021-01-12T08:12:44Z
day: '19'
ddc:
- '540'
- '547'
doi: 10.1038/s41557-019-0311-0
extern: '1'
file:
- access_level: open_access
checksum: 76806cff3d5b62f846499a8617cee7ef
content_type: application/pdf
creator: sfreunbe
date_created: 2020-06-29T15:38:21Z
date_updated: 2020-07-14T12:47:55Z
file_id: '8054'
file_name: Freunberger on Eichhorn.pdf
file_size: 286805
relation: main_file
file_date_updated: 2020-07-14T12:47:55Z
has_accepted_license: '1'
intvolume: ' 11'
issue: '9'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Submitted Version
page: 761-763
publication: Nature Chemistry
publication_identifier:
issn:
- 1755-4330
- 1755-4349
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Interphase identity crisis
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 11
year: '2019'
...
---
_id: '7283'
abstract:
- lang: eng
text: Potassium–air batteries, which suffer from oxygen cathode and potassium metal
anode degradation, can be cycled thousands of times when an organic anode replaces
the metal.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Yann K.
full_name: Petit, Yann K.
last_name: Petit
- first_name: Stefan Alexander
full_name: Freunberger, Stefan Alexander
id: A8CA28E6-CE23-11E9-AD2D-EC27E6697425
last_name: Freunberger
orcid: 0000-0003-2902-5319
citation:
ama: Petit YK, Freunberger SA. Thousands of cycles. Nature Materials. 2019;18(4):301-302.
doi:10.1038/s41563-019-0313-8
apa: Petit, Y. K., & Freunberger, S. A. (2019). Thousands of cycles. Nature
Materials. Springer Nature. https://doi.org/10.1038/s41563-019-0313-8
chicago: Petit, Yann K., and Stefan Alexander Freunberger. “Thousands of Cycles.”
Nature Materials. Springer Nature, 2019. https://doi.org/10.1038/s41563-019-0313-8.
ieee: Y. K. Petit and S. A. Freunberger, “Thousands of cycles,” Nature Materials,
vol. 18, no. 4. Springer Nature, pp. 301–302, 2019.
ista: Petit YK, Freunberger SA. 2019. Thousands of cycles. Nature Materials. 18(4),
301–302.
mla: Petit, Yann K., and Stefan Alexander Freunberger. “Thousands of Cycles.” Nature
Materials, vol. 18, no. 4, Springer Nature, 2019, pp. 301–02, doi:10.1038/s41563-019-0313-8.
short: Y.K. Petit, S.A. Freunberger, Nature Materials 18 (2019) 301–302.
date_created: 2020-01-15T12:13:05Z
date_published: 2019-03-20T00:00:00Z
date_updated: 2021-01-12T08:12:45Z
day: '20'
ddc:
- '540'
- '541'
doi: 10.1038/s41563-019-0313-8
extern: '1'
file:
- access_level: open_access
checksum: 4c9a0314327028a22dd902bc109b8798
content_type: application/pdf
creator: sfreunbe
date_created: 2020-06-29T16:26:54Z
date_updated: 2020-07-14T12:47:55Z
file_id: '8059'
file_name: NaV_final.pdf
file_size: 398123
relation: main_file
file_date_updated: 2020-07-14T12:47:55Z
has_accepted_license: '1'
intvolume: ' 18'
issue: '4'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Submitted Version
page: 301-302
publication: Nature Materials
publication_identifier:
issn:
- 1476-1122
- 1476-4660
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Thousands of cycles
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 18
year: '2019'
...
---
_id: '7284'
abstract:
- lang: eng
text: In this issue of Joule, Dongmin Im and coworkers from Samsung in South Korea
describe a prototype lithium-O2 battery that reaches ∼700 Wh kg–1 and ∼600 Wh
L–1 on the cell level. They cut all components to the minimum to reach this value.
Difficulties filling the pores with discharge product and inhomogeneous cell utilization
turn out to limit the achievable energy. Their work underlines the importance
of reporting performance with respect to full cell weight and volume.
article_processing_charge: No
article_type: review
author:
- first_name: Christian
full_name: Prehal, Christian
last_name: Prehal
- first_name: Stefan Alexander
full_name: Freunberger, Stefan Alexander
id: A8CA28E6-CE23-11E9-AD2D-EC27E6697425
last_name: Freunberger
orcid: 0000-0003-2902-5319
citation:
ama: Prehal C, Freunberger SA. Li-O2 cell-scale energy densities. Joule.
2019;3(2):321-323. doi:10.1016/j.joule.2019.01.020
apa: Prehal, C., & Freunberger, S. A. (2019). Li-O2 cell-scale energy densities.
Joule. Elsevier. https://doi.org/10.1016/j.joule.2019.01.020
chicago: Prehal, Christian, and Stefan Alexander Freunberger. “Li-O2 Cell-Scale
Energy Densities.” Joule. Elsevier, 2019. https://doi.org/10.1016/j.joule.2019.01.020.
ieee: C. Prehal and S. A. Freunberger, “Li-O2 cell-scale energy densities,” Joule,
vol. 3, no. 2. Elsevier, pp. 321–323, 2019.
ista: Prehal C, Freunberger SA. 2019. Li-O2 cell-scale energy densities. Joule.
3(2), 321–323.
mla: Prehal, Christian, and Stefan Alexander Freunberger. “Li-O2 Cell-Scale Energy
Densities.” Joule, vol. 3, no. 2, Elsevier, 2019, pp. 321–23, doi:10.1016/j.joule.2019.01.020.
short: C. Prehal, S.A. Freunberger, Joule 3 (2019) 321–323.
date_created: 2020-01-15T12:13:15Z
date_published: 2019-02-20T00:00:00Z
date_updated: 2021-01-12T08:12:45Z
day: '20'
doi: 10.1016/j.joule.2019.01.020
extern: '1'
intvolume: ' 3'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.doi.org/10.1016/j.joule.2019.01.020
month: '02'
oa: 1
oa_version: Published Version
page: 321-323
publication: Joule
publication_identifier:
issn:
- 2542-4351
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: Li-O2 cell-scale energy densities
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 3
year: '2019'
...
---
_id: '73'
abstract:
- lang: eng
text: We consider the space of probability measures on a discrete set X, endowed
with a dynamical optimal transport metric. Given two probability measures supported
in a subset Y⊆X, it is natural to ask whether they can be connected by a constant
speed geodesic with support in Y at all times. Our main result answers this question
affirmatively, under a suitable geometric condition on Y introduced in this paper.
The proof relies on an extension result for subsolutions to discrete Hamilton-Jacobi
equations, which is of independent interest.
article_number: '19'
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Matthias
full_name: Erbar, Matthias
last_name: Erbar
- first_name: Jan
full_name: Maas, Jan
id: 4C5696CE-F248-11E8-B48F-1D18A9856A87
last_name: Maas
orcid: 0000-0002-0845-1338
- first_name: Melchior
full_name: Wirth, Melchior
last_name: Wirth
citation:
ama: Erbar M, Maas J, Wirth M. On the geometry of geodesics in discrete optimal
transport. Calculus of Variations and Partial Differential Equations. 2019;58(1).
doi:10.1007/s00526-018-1456-1
apa: Erbar, M., Maas, J., & Wirth, M. (2019). On the geometry of geodesics in
discrete optimal transport. Calculus of Variations and Partial Differential
Equations. Springer. https://doi.org/10.1007/s00526-018-1456-1
chicago: Erbar, Matthias, Jan Maas, and Melchior Wirth. “On the Geometry of Geodesics
in Discrete Optimal Transport.” Calculus of Variations and Partial Differential
Equations. Springer, 2019. https://doi.org/10.1007/s00526-018-1456-1.
ieee: M. Erbar, J. Maas, and M. Wirth, “On the geometry of geodesics in discrete
optimal transport,” Calculus of Variations and Partial Differential Equations,
vol. 58, no. 1. Springer, 2019.
ista: Erbar M, Maas J, Wirth M. 2019. On the geometry of geodesics in discrete optimal
transport. Calculus of Variations and Partial Differential Equations. 58(1), 19.
mla: Erbar, Matthias, et al. “On the Geometry of Geodesics in Discrete Optimal Transport.”
Calculus of Variations and Partial Differential Equations, vol. 58, no.
1, 19, Springer, 2019, doi:10.1007/s00526-018-1456-1.
short: M. Erbar, J. Maas, M. Wirth, Calculus of Variations and Partial Differential
Equations 58 (2019).
date_created: 2018-12-11T11:44:29Z
date_published: 2019-02-01T00:00:00Z
date_updated: 2023-09-13T09:12:35Z
day: '01'
ddc:
- '510'
department:
- _id: JaMa
doi: 10.1007/s00526-018-1456-1
ec_funded: 1
external_id:
arxiv:
- '1805.06040'
isi:
- '000452849400001'
file:
- access_level: open_access
checksum: ba05ac2d69de4c58d2cd338b63512798
content_type: application/pdf
creator: dernst
date_created: 2019-01-28T15:37:11Z
date_updated: 2020-07-14T12:47:55Z
file_id: '5895'
file_name: 2018_Calculus_Erbar.pdf
file_size: 645565
relation: main_file
file_date_updated: 2020-07-14T12:47:55Z
has_accepted_license: '1'
intvolume: ' 58'
isi: 1
issue: '1'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
project:
- _id: 256E75B8-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '716117'
name: Optimal Transport and Stochastic Dynamics
- _id: 260482E2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: ' F06504'
name: Taming Complexity in Partial Di erential Systems
- _id: B67AFEDC-15C9-11EA-A837-991A96BB2854
name: IST Austria Open Access Fund
publication: Calculus of Variations and Partial Differential Equations
publication_identifier:
issn:
- '09442669'
publication_status: published
publisher: Springer
quality_controlled: '1'
scopus_import: '1'
status: public
title: On the geometry of geodesics in discrete optimal transport
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 58
year: '2019'
...
---
_id: '7340'
abstract:
- lang: eng
text: Coupling of endoplasmic reticulum stress to dimerisation‑dependent activation
of the UPR transducer IRE1 is incompletely understood. Whilst the luminal co-chaperone
ERdj4 promotes a complex between the Hsp70 BiP and IRE1's stress-sensing luminal
domain (IRE1LD) that favours the latter's monomeric inactive state and loss of
ERdj4 de-represses IRE1, evidence linking these cellular and in vitro observations
is presently lacking. We report that enforced loading of endogenous BiP onto endogenous
IRE1α repressed UPR signalling in CHO cells and deletions in the IRE1α locus that
de-repressed the UPR in cells, encode flexible regions of IRE1LD that mediated
BiP‑induced monomerisation in vitro. Changes in the hydrogen exchange mass spectrometry
profile of IRE1LD induced by ERdj4 and BiP confirmed monomerisation and were consistent
with active destabilisation of the IRE1LD dimer. Together, these observations
support a competition model whereby waning ER stress passively partitions ERdj4
and BiP to IRE1LD to initiate active repression of UPR signalling.
acknowledgement: We thank the CIMR flow cytometry core facility team (Reiner Schulte,
Chiara Cossetti and Gabriela Grondys-Kotarba) for assistance with FACS, the Huntington
lab for access to the Octet machine, Steffen Preissler for advice on data interpretation,
Roman Kityk and Nicole Luebbehusen for help and advice with HX-MS experiments.
article_number: e50793
article_processing_charge: No
article_type: original
author:
- first_name: Niko Paresh
full_name: Amin-Wetzel, Niko Paresh
id: E95D3014-9D8C-11E9-9C80-D2F8E5697425
last_name: Amin-Wetzel
- first_name: Lisa
full_name: Neidhardt, Lisa
last_name: Neidhardt
- first_name: Yahui
full_name: Yan, Yahui
last_name: Yan
- first_name: Matthias P.
full_name: Mayer, Matthias P.
last_name: Mayer
- first_name: David
full_name: Ron, David
last_name: Ron
citation:
ama: Amin-Wetzel NP, Neidhardt L, Yan Y, Mayer MP, Ron D. Unstructured regions in
IRE1α specify BiP-mediated destabilisation of the luminal domain dimer and repression
of the UPR. eLife. 2019;8. doi:10.7554/eLife.50793
apa: Amin-Wetzel, N. P., Neidhardt, L., Yan, Y., Mayer, M. P., & Ron, D. (2019).
Unstructured regions in IRE1α specify BiP-mediated destabilisation of the luminal
domain dimer and repression of the UPR. ELife. eLife Sciences Publications.
https://doi.org/10.7554/eLife.50793
chicago: Amin-Wetzel, Niko Paresh, Lisa Neidhardt, Yahui Yan, Matthias P. Mayer,
and David Ron. “Unstructured Regions in IRE1α Specify BiP-Mediated Destabilisation
of the Luminal Domain Dimer and Repression of the UPR.” ELife. eLife Sciences
Publications, 2019. https://doi.org/10.7554/eLife.50793.
ieee: N. P. Amin-Wetzel, L. Neidhardt, Y. Yan, M. P. Mayer, and D. Ron, “Unstructured
regions in IRE1α specify BiP-mediated destabilisation of the luminal domain dimer
and repression of the UPR,” eLife, vol. 8. eLife Sciences Publications,
2019.
ista: Amin-Wetzel NP, Neidhardt L, Yan Y, Mayer MP, Ron D. 2019. Unstructured regions
in IRE1α specify BiP-mediated destabilisation of the luminal domain dimer and
repression of the UPR. eLife. 8, e50793.
mla: Amin-Wetzel, Niko Paresh, et al. “Unstructured Regions in IRE1α Specify BiP-Mediated
Destabilisation of the Luminal Domain Dimer and Repression of the UPR.” ELife,
vol. 8, e50793, eLife Sciences Publications, 2019, doi:10.7554/eLife.50793.
short: N.P. Amin-Wetzel, L. Neidhardt, Y. Yan, M.P. Mayer, D. Ron, ELife 8 (2019).
date_created: 2020-01-19T23:00:39Z
date_published: 2019-12-24T00:00:00Z
date_updated: 2023-09-06T14:58:02Z
day: '24'
ddc:
- '570'
department:
- _id: MaDe
doi: 10.7554/eLife.50793
external_id:
isi:
- '000512303700001'
pmid:
- '31873072'
file:
- access_level: open_access
checksum: 29fcbcd8c1fc7f11a596ed7f14ea1c82
content_type: application/pdf
creator: dernst
date_created: 2020-11-19T11:37:41Z
date_updated: 2020-11-19T11:37:41Z
file_id: '8777'
file_name: 2019_eLife_AminWetzel.pdf
file_size: 4817384
relation: main_file
success: 1
file_date_updated: 2020-11-19T11:37:41Z
has_accepted_license: '1'
intvolume: ' 8'
isi: 1
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
pmid: 1
publication: eLife
publication_identifier:
eissn:
- 2050084X
publication_status: published
publisher: eLife Sciences Publications
quality_controlled: '1'
scopus_import: '1'
status: public
title: Unstructured regions in IRE1α specify BiP-mediated destabilisation of the luminal
domain dimer and repression of the UPR
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 8
year: '2019'
...
---
_id: '7358'
abstract:
- lang: eng
text: Telencephalic organoids generated from human pluripotent stem cells (hPSCs)
are emerging as an effective system to study the distinct features of the developing
human brain and the underlying causes of many neurological disorders. While progress
in organoid technology has been steadily advancing, many challenges remain including
rampant batch-to-batch and cell line-to-cell line variability and irreproducibility.
Here, we demonstrate that a major contributor to successful cortical organoid
production is the manner in which hPSCs are maintained prior to differentiation.
Optimal results were achieved using fibroblast-feeder-supported hPSCs compared
to feeder-independent cells, related to differences in their transcriptomic states.
Feeder-supported hPSCs display elevated activation of diverse TGFβ superfamily
signaling pathways and increased expression of genes associated with naïve pluripotency.
We further identify combinations of TGFβ-related growth factors that are necessary
and together sufficient to impart broad telencephalic organoid competency to feeder-free
hPSCs and enable reproducible formation of brain structures suitable for disease
modeling.
article_processing_charge: No
author:
- first_name: Momoko
full_name: Watanabe, Momoko
last_name: Watanabe
- first_name: Jillian R.
full_name: Haney, Jillian R.
last_name: Haney
- first_name: Neda
full_name: Vishlaghi, Neda
last_name: Vishlaghi
- first_name: Felix
full_name: Turcios, Felix
last_name: Turcios
- first_name: Jessie E.
full_name: Buth, Jessie E.
last_name: Buth
- first_name: Wen
full_name: Gu, Wen
last_name: Gu
- first_name: Amanda J.
full_name: Collier, Amanda J.
last_name: Collier
- first_name: Osvaldo
full_name: Miranda, Osvaldo
id: 862A3C56-A8BF-11E9-B4FA-D9E3E5697425
last_name: Miranda
orcid: 0000-0001-6618-6889
- first_name: Di
full_name: Chen, Di
last_name: Chen
- first_name: Shan
full_name: Sabri, Shan
last_name: Sabri
- first_name: Amander T.
full_name: Clark, Amander T.
last_name: Clark
- first_name: Kathrin
full_name: Plath, Kathrin
last_name: Plath
- first_name: Heather R.
full_name: Christofk, Heather R.
last_name: Christofk
- first_name: Michael J.
full_name: Gandal, Michael J.
last_name: Gandal
- first_name: Bennett G.
full_name: Novitch, Bennett G.
last_name: Novitch
citation:
ama: Watanabe M, Haney JR, Vishlaghi N, et al. TGFβ superfamily signaling regulates
the state of human stem cell pluripotency and competency to create telencephalic
organoids. bioRxiv. 2019. doi:10.1101/2019.12.13.875773
apa: Watanabe, M., Haney, J. R., Vishlaghi, N., Turcios, F., Buth, J. E., Gu, W.,
… Novitch, B. G. (2019). TGFβ superfamily signaling regulates the state of human
stem cell pluripotency and competency to create telencephalic organoids. bioRxiv.
Cold Spring Harbor Laboratory. https://doi.org/10.1101/2019.12.13.875773
chicago: Watanabe, Momoko, Jillian R. Haney, Neda Vishlaghi, Felix Turcios, Jessie
E. Buth, Wen Gu, Amanda J. Collier, et al. “TGFβ Superfamily Signaling Regulates
the State of Human Stem Cell Pluripotency and Competency to Create Telencephalic
Organoids.” BioRxiv. Cold Spring Harbor Laboratory, 2019. https://doi.org/10.1101/2019.12.13.875773.
ieee: M. Watanabe et al., “TGFβ superfamily signaling regulates the state
of human stem cell pluripotency and competency to create telencephalic organoids,”
bioRxiv. Cold Spring Harbor Laboratory, 2019.
ista: Watanabe M, Haney JR, Vishlaghi N, Turcios F, Buth JE, Gu W, Collier AJ, Miranda
O, Chen D, Sabri S, Clark AT, Plath K, Christofk HR, Gandal MJ, Novitch BG. 2019.
TGFβ superfamily signaling regulates the state of human stem cell pluripotency
and competency to create telencephalic organoids. bioRxiv, 10.1101/2019.12.13.875773.
mla: Watanabe, Momoko, et al. “TGFβ Superfamily Signaling Regulates the State of
Human Stem Cell Pluripotency and Competency to Create Telencephalic Organoids.”
BioRxiv, Cold Spring Harbor Laboratory, 2019, doi:10.1101/2019.12.13.875773.
short: M. Watanabe, J.R. Haney, N. Vishlaghi, F. Turcios, J.E. Buth, W. Gu, A.J.
Collier, O. Miranda, D. Chen, S. Sabri, A.T. Clark, K. Plath, H.R. Christofk,
M.J. Gandal, B.G. Novitch, BioRxiv (2019).
date_created: 2020-01-23T09:53:40Z
date_published: 2019-12-13T00:00:00Z
date_updated: 2022-06-17T08:03:32Z
day: '13'
doi: 10.1101/2019.12.13.875773
extern: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1101/2019.12.13.875773
month: '12'
oa: 1
oa_version: Preprint
page: '75'
publication: bioRxiv
publication_status: published
publisher: Cold Spring Harbor Laboratory
status: public
title: TGFβ superfamily signaling regulates the state of human stem cell pluripotency
and competency to create telencephalic organoids
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2019'
...
---
_id: '7391'
abstract:
- lang: eng
text: Electron microscopy (EM) is a technology that enables visualization of single
proteins at a nanometer resolution. However, current protein analysis by EM mainly
relies on immunolabeling with gold-particle-conjugated antibodies, which is compromised
by large size of antibody, precluding precise detection of protein location in
biological samples. Here, we develop a specific chemical labeling method for EM
detection of proteins at single-molecular level. Rational design of α-helical
peptide tag and probe structure provided a complementary reaction pair that enabled
specific cysteine conjugation of the tag. The developed chemical labeling with
gold-nanoparticle-conjugated probe showed significantly higher labeling efficiency
and detectability of high-density clusters of tag-fused G protein-coupled receptors
in freeze-fracture replicas compared with immunogold labeling. Furthermore, in
ultrathin sections, the spatial resolution of the chemical labeling was significantly
higher than that of antibody-mediated labeling. These results demonstrate substantial
advantages of the chemical labeling approach for single protein visualization
by EM.
article_processing_charge: No
article_type: original
author:
- first_name: Shigekazu
full_name: Tabata, Shigekazu
id: 4427179E-F248-11E8-B48F-1D18A9856A87
last_name: Tabata
- first_name: Marijo
full_name: Jevtic, Marijo
id: 4BE3BC94-F248-11E8-B48F-1D18A9856A87
last_name: Jevtic
- first_name: Nobutaka
full_name: Kurashige, Nobutaka
last_name: Kurashige
- first_name: Hirokazu
full_name: Fuchida, Hirokazu
last_name: Fuchida
- first_name: Munetsugu
full_name: Kido, Munetsugu
last_name: Kido
- first_name: Kazushi
full_name: Tani, Kazushi
last_name: Tani
- first_name: Naoki
full_name: Zenmyo, Naoki
last_name: Zenmyo
- first_name: Shohei
full_name: Uchinomiya, Shohei
last_name: Uchinomiya
- first_name: Harumi
full_name: Harada, Harumi
id: 2E55CDF2-F248-11E8-B48F-1D18A9856A87
last_name: Harada
orcid: 0000-0001-7429-7896
- first_name: Makoto
full_name: Itakura, Makoto
last_name: Itakura
- first_name: Itaru
full_name: Hamachi, Itaru
last_name: Hamachi
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Akio
full_name: Ojida, Akio
last_name: Ojida
citation:
ama: Tabata S, Jevtic M, Kurashige N, et al. Electron microscopic detection of single
membrane proteins by a specific chemical labeling. iScience. 2019;22(12):256-268.
doi:10.1016/j.isci.2019.11.025
apa: Tabata, S., Jevtic, M., Kurashige, N., Fuchida, H., Kido, M., Tani, K., … Ojida,
A. (2019). Electron microscopic detection of single membrane proteins by a specific
chemical labeling. IScience. Elsevier. https://doi.org/10.1016/j.isci.2019.11.025
chicago: Tabata, Shigekazu, Marijo Jevtic, Nobutaka Kurashige, Hirokazu Fuchida,
Munetsugu Kido, Kazushi Tani, Naoki Zenmyo, et al. “Electron Microscopic Detection
of Single Membrane Proteins by a Specific Chemical Labeling.” IScience.
Elsevier, 2019. https://doi.org/10.1016/j.isci.2019.11.025.
ieee: S. Tabata et al., “Electron microscopic detection of single membrane
proteins by a specific chemical labeling,” iScience, vol. 22, no. 12. Elsevier,
pp. 256–268, 2019.
ista: Tabata S, Jevtic M, Kurashige N, Fuchida H, Kido M, Tani K, Zenmyo N, Uchinomiya
S, Harada H, Itakura M, Hamachi I, Shigemoto R, Ojida A. 2019. Electron microscopic
detection of single membrane proteins by a specific chemical labeling. iScience.
22(12), 256–268.
mla: Tabata, Shigekazu, et al. “Electron Microscopic Detection of Single Membrane
Proteins by a Specific Chemical Labeling.” IScience, vol. 22, no. 12, Elsevier,
2019, pp. 256–68, doi:10.1016/j.isci.2019.11.025.
short: S. Tabata, M. Jevtic, N. Kurashige, H. Fuchida, M. Kido, K. Tani, N. Zenmyo,
S. Uchinomiya, H. Harada, M. Itakura, I. Hamachi, R. Shigemoto, A. Ojida, IScience
22 (2019) 256–268.
date_created: 2020-01-29T15:56:56Z
date_published: 2019-12-20T00:00:00Z
date_updated: 2024-03-25T23:30:07Z
day: '20'
ddc:
- '570'
department:
- _id: RySh
doi: 10.1016/j.isci.2019.11.025
ec_funded: 1
external_id:
isi:
- :000504652000020
pmid:
- '31786521'
file:
- access_level: open_access
checksum: f3e90056a49f09b205b1c4f8c739ffd1
content_type: application/pdf
creator: dernst
date_created: 2020-02-04T10:48:36Z
date_updated: 2020-07-14T12:47:57Z
file_id: '7448'
file_name: 2019_iScience_Tabata.pdf
file_size: 7197776
relation: main_file
file_date_updated: 2020-07-14T12:47:57Z
has_accepted_license: '1'
intvolume: ' 22'
issue: '12'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 256-268
pmid: 1
project:
- _id: 25CA28EA-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '694539'
name: 'In situ analysis of single channel subunit composition in neurons: physiological
implication in synaptic plasticity and behaviour'
- _id: 25CBA828-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '720270'
name: Human Brain Project Specific Grant Agreement 1 (HBP SGA 1)
publication: iScience
publication_identifier:
issn:
- 2589-0042
publication_status: published
publisher: Elsevier
quality_controlled: '1'
related_material:
record:
- id: '11393'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Electron microscopic detection of single membrane proteins by a specific chemical
labeling
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 22
year: '2019'
...
---
_id: '7393'
abstract:
- lang: eng
text: The study of parallel ecological divergence provides important clues to the
operation of natural selection. Parallel divergence often occurs in heterogeneous
environments with different kinds of environmental gradients in different locations,
but the genomic basis underlying this process is unknown. We investigated the
genomics of rapid parallel adaptation in the marine snail Littorina saxatilis
in response to two independent environmental axes (crab-predation versus wave-action
and low-shore versus high-shore). Using pooled whole-genome resequencing, we show
that sharing of genomic regions of high differentiation between environments is
generally low but increases at smaller spatial scales. We identify different shared
genomic regions of divergence for each environmental axis and show that most of
these regions overlap with candidate chromosomal inversions. Several inversion
regions are divergent and polymorphic across many localities. We argue that chromosomal
inversions could store shared variation that fuels rapid parallel adaptation to
heterogeneous environments, possibly as balanced polymorphism shared by adaptive
gene flow.
article_number: eaav9963
article_processing_charge: No
article_type: original
author:
- first_name: Hernán E.
full_name: Morales, Hernán E.
last_name: Morales
- first_name: Rui
full_name: Faria, Rui
last_name: Faria
- first_name: Kerstin
full_name: Johannesson, Kerstin
last_name: Johannesson
- first_name: Tomas
full_name: Larsson, Tomas
last_name: Larsson
- first_name: Marina
full_name: Panova, Marina
last_name: Panova
- first_name: Anja M
full_name: Westram, Anja M
id: 3C147470-F248-11E8-B48F-1D18A9856A87
last_name: Westram
orcid: 0000-0003-1050-4969
- first_name: Roger K.
full_name: Butlin, Roger K.
last_name: Butlin
citation:
ama: 'Morales HE, Faria R, Johannesson K, et al. Genomic architecture of parallel
ecological divergence: Beyond a single environmental contrast. Science Advances.
2019;5(12). doi:10.1126/sciadv.aav9963'
apa: 'Morales, H. E., Faria, R., Johannesson, K., Larsson, T., Panova, M., Westram,
A. M., & Butlin, R. K. (2019). Genomic architecture of parallel ecological
divergence: Beyond a single environmental contrast. Science Advances. AAAS.
https://doi.org/10.1126/sciadv.aav9963'
chicago: 'Morales, Hernán E., Rui Faria, Kerstin Johannesson, Tomas Larsson, Marina
Panova, Anja M Westram, and Roger K. Butlin. “Genomic Architecture of Parallel
Ecological Divergence: Beyond a Single Environmental Contrast.” Science Advances.
AAAS, 2019. https://doi.org/10.1126/sciadv.aav9963.'
ieee: 'H. E. Morales et al., “Genomic architecture of parallel ecological
divergence: Beyond a single environmental contrast,” Science Advances,
vol. 5, no. 12. AAAS, 2019.'
ista: 'Morales HE, Faria R, Johannesson K, Larsson T, Panova M, Westram AM, Butlin
RK. 2019. Genomic architecture of parallel ecological divergence: Beyond a single
environmental contrast. Science Advances. 5(12), eaav9963.'
mla: 'Morales, Hernán E., et al. “Genomic Architecture of Parallel Ecological Divergence:
Beyond a Single Environmental Contrast.” Science Advances, vol. 5, no.
12, eaav9963, AAAS, 2019, doi:10.1126/sciadv.aav9963.'
short: H.E. Morales, R. Faria, K. Johannesson, T. Larsson, M. Panova, A.M. Westram,
R.K. Butlin, Science Advances 5 (2019).
date_created: 2020-01-29T15:58:27Z
date_published: 2019-12-04T00:00:00Z
date_updated: 2023-09-06T15:35:56Z
day: '04'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1126/sciadv.aav9963
ec_funded: 1
external_id:
isi:
- '000505069600008'
pmid:
- '31840052'
file:
- access_level: open_access
checksum: af99a5dcdc66c6d6102051faf3be48d8
content_type: application/pdf
creator: dernst
date_created: 2020-02-03T13:33:25Z
date_updated: 2020-07-14T12:47:57Z
file_id: '7442'
file_name: 2019_ScienceAdvances_Morales.pdf
file_size: 1869449
relation: main_file
file_date_updated: 2020-07-14T12:47:57Z
has_accepted_license: '1'
intvolume: ' 5'
isi: 1
issue: '12'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
- _id: 265B41B8-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '797747'
name: Theoretical and empirical approaches to understanding Parallel Adaptation
publication: Science Advances
publication_identifier:
issn:
- 2375-2548
publication_status: published
publisher: AAAS
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Genomic architecture of parallel ecological divergence: Beyond a single environmental
contrast'
tmp:
image: /images/cc_by_nc.png
legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
short: CC BY-NC (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 5
year: '2019'
...
---
_id: '7394'
article_processing_charge: No
article_type: letter_note
author:
- first_name: Eva
full_name: Benková, Eva
id: 38F4F166-F248-11E8-B48F-1D18A9856A87
last_name: Benková
orcid: 0000-0002-8510-9739
- first_name: Yasin
full_name: Dagdas, Yasin
last_name: Dagdas
citation:
ama: 'Benková E, Dagdas Y. Editorial overview: Cell biology in the era of omics?
Current Opinion in Plant Biology. 2019;52(12):A1-A2. doi:10.1016/j.pbi.2019.11.002'
apa: 'Benková, E., & Dagdas, Y. (2019). Editorial overview: Cell biology in
the era of omics? Current Opinion in Plant Biology. Elsevier. https://doi.org/10.1016/j.pbi.2019.11.002'
chicago: 'Benková, Eva, and Yasin Dagdas. “Editorial Overview: Cell Biology in the
Era of Omics?” Current Opinion in Plant Biology. Elsevier, 2019. https://doi.org/10.1016/j.pbi.2019.11.002.'
ieee: 'E. Benková and Y. Dagdas, “Editorial overview: Cell biology in the era of
omics?,” Current Opinion in Plant Biology, vol. 52, no. 12. Elsevier, pp.
A1–A2, 2019.'
ista: 'Benková E, Dagdas Y. 2019. Editorial overview: Cell biology in the era of
omics? Current Opinion in Plant Biology. 52(12), A1–A2.'
mla: 'Benková, Eva, and Yasin Dagdas. “Editorial Overview: Cell Biology in the Era
of Omics?” Current Opinion in Plant Biology, vol. 52, no. 12, Elsevier,
2019, pp. A1–2, doi:10.1016/j.pbi.2019.11.002.'
short: E. Benková, Y. Dagdas, Current Opinion in Plant Biology 52 (2019) A1–A2.
date_created: 2020-01-29T16:00:07Z
date_published: 2019-12-01T00:00:00Z
date_updated: 2023-09-07T14:56:55Z
day: '01'
department:
- _id: EvBe
doi: 10.1016/j.pbi.2019.11.002
external_id:
isi:
- '000502890600001'
pmid:
- '31787165'
intvolume: ' 52'
isi: 1
issue: '12'
language:
- iso: eng
month: '12'
oa_version: None
page: A1-A2
pmid: 1
publication: Current Opinion in Plant Biology
publication_identifier:
issn:
- 1369-5266
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Editorial overview: Cell biology in the era of omics?'
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 52
year: '2019'
...
---
_id: '7395'
abstract:
- lang: eng
text: The mitochondrial electron transport chain complexes are organized into supercomplexes
(SCs) of defined stoichiometry, which have been proposed to regulate electron
flux via substrate channeling. We demonstrate that CoQ trapping in the isolated
SC I+III2 limits complex (C)I turnover, arguing against channeling. The SC structure,
resolved at up to 3.8 Å in four distinct states, suggests that CoQ oxidation may
be rate limiting because of unequal access of CoQ to the active sites of CIII2.
CI shows a transition between “closed” and “open” conformations, accompanied by
the striking rotation of a key transmembrane helix. Furthermore, the state of
CI affects the conformational flexibility within CIII2, demonstrating crosstalk
between the enzymes. CoQ was identified at only three of the four binding sites
in CIII2, suggesting that interaction with CI disrupts CIII2 symmetry in a functionally
relevant manner. Together, these observations indicate a more nuanced functional
role for the SCs.
article_processing_charge: No
article_type: original
author:
- first_name: James A
full_name: Letts, James A
id: 322DA418-F248-11E8-B48F-1D18A9856A87
last_name: Letts
orcid: 0000-0002-9864-3586
- first_name: Karol
full_name: Fiedorczuk, Karol
id: 5BFF67CE-02D1-11E9-B11A-A5A4D7DFFFD0
last_name: Fiedorczuk
- first_name: Gianluca
full_name: Degliesposti, Gianluca
last_name: Degliesposti
- first_name: Mark
full_name: Skehel, Mark
last_name: Skehel
- first_name: Leonid A
full_name: Sazanov, Leonid A
id: 338D39FE-F248-11E8-B48F-1D18A9856A87
last_name: Sazanov
orcid: 0000-0002-0977-7989
citation:
ama: Letts JA, Fiedorczuk K, Degliesposti G, Skehel M, Sazanov LA. Structures of
respiratory supercomplex I+III2 reveal functional and conformational crosstalk.
Molecular Cell. 2019;75(6):1131-1146.e6. doi:10.1016/j.molcel.2019.07.022
apa: Letts, J. A., Fiedorczuk, K., Degliesposti, G., Skehel, M., & Sazanov,
L. A. (2019). Structures of respiratory supercomplex I+III2 reveal functional
and conformational crosstalk. Molecular Cell. Cell Press. https://doi.org/10.1016/j.molcel.2019.07.022
chicago: Letts, James A, Karol Fiedorczuk, Gianluca Degliesposti, Mark Skehel, and
Leonid A Sazanov. “Structures of Respiratory Supercomplex I+III2 Reveal Functional
and Conformational Crosstalk.” Molecular Cell. Cell Press, 2019. https://doi.org/10.1016/j.molcel.2019.07.022.
ieee: J. A. Letts, K. Fiedorczuk, G. Degliesposti, M. Skehel, and L. A. Sazanov,
“Structures of respiratory supercomplex I+III2 reveal functional and conformational
crosstalk,” Molecular Cell, vol. 75, no. 6. Cell Press, p. 1131–1146.e6,
2019.
ista: Letts JA, Fiedorczuk K, Degliesposti G, Skehel M, Sazanov LA. 2019. Structures
of respiratory supercomplex I+III2 reveal functional and conformational crosstalk.
Molecular Cell. 75(6), 1131–1146.e6.
mla: Letts, James A., et al. “Structures of Respiratory Supercomplex I+III2 Reveal
Functional and Conformational Crosstalk.” Molecular Cell, vol. 75, no.
6, Cell Press, 2019, p. 1131–1146.e6, doi:10.1016/j.molcel.2019.07.022.
short: J.A. Letts, K. Fiedorczuk, G. Degliesposti, M. Skehel, L.A. Sazanov, Molecular
Cell 75 (2019) 1131–1146.e6.
date_created: 2020-01-29T16:02:33Z
date_published: 2019-09-19T00:00:00Z
date_updated: 2023-09-07T14:53:06Z
day: '19'
ddc:
- '570'
department:
- _id: LeSa
doi: 10.1016/j.molcel.2019.07.022
ec_funded: 1
external_id:
isi:
- '000486614200006'
pmid:
- '31492636'
file:
- access_level: open_access
checksum: 5202f53a237d6650ece038fbf13bdcea
content_type: application/pdf
creator: dernst
date_created: 2020-02-04T10:37:28Z
date_updated: 2020-07-14T12:47:57Z
file_id: '7447'
file_name: 2019_MolecularCell_Letts.pdf
file_size: 9654895
relation: main_file
file_date_updated: 2020-07-14T12:47:57Z
has_accepted_license: '1'
intvolume: ' 75'
isi: 1
issue: '6'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: 1131-1146.e6
pmid: 1
project:
- _id: 2590DB08-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '701309'
name: Atomic-Resolution Structures of Mitochondrial Respiratory Chain Supercomplexes
publication: Molecular Cell
publication_identifier:
issn:
- 1097-2765
publication_status: published
publisher: Cell Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Structures of respiratory supercomplex I+III2 reveal functional and conformational
crosstalk
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 75
year: '2019'
...
---
_id: '7396'
abstract:
- lang: eng
text: The angular momentum of molecules, or, equivalently, their rotation in three-dimensional
space, is ideally suited for quantum control. Molecular angular momentum is naturally
quantized, time evolution is governed by a well-known Hamiltonian with only a
few accurately known parameters, and transitions between rotational levels can
be driven by external fields from various parts of the electromagnetic spectrum.
Control over the rotational motion can be exerted in one-, two-, and many-body
scenarios, thereby allowing one to probe Anderson localization, target stereoselectivity
of bimolecular reactions, or encode quantum information to name just a few examples.
The corresponding approaches to quantum control are pursued within separate, and
typically disjoint, subfields of physics, including ultrafast science, cold collisions,
ultracold gases, quantum information science, and condensed-matter physics. It
is the purpose of this review to present the various control phenomena, which
all rely on the same underlying physics, within a unified framework. To this end,
recall the Hamiltonian for free rotations, assuming the rigid rotor approximation
to be valid, and summarize the different ways for a rotor to interact with external
electromagnetic fields. These interactions can be exploited for control—from achieving
alignment, orientation, or laser cooling in a one-body framework, steering bimolecular
collisions, or realizing a quantum computer or quantum simulator in the many-body
setting.
article_number: '035005 '
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Christiane P.
full_name: Koch, Christiane P.
last_name: Koch
- first_name: Mikhail
full_name: Lemeshko, Mikhail
id: 37CB05FA-F248-11E8-B48F-1D18A9856A87
last_name: Lemeshko
orcid: 0000-0002-6990-7802
- first_name: Dominique
full_name: Sugny, Dominique
last_name: Sugny
citation:
ama: Koch CP, Lemeshko M, Sugny D. Quantum control of molecular rotation. Reviews
of Modern Physics. 2019;91(3). doi:10.1103/revmodphys.91.035005
apa: Koch, C. P., Lemeshko, M., & Sugny, D. (2019). Quantum control of molecular
rotation. Reviews of Modern Physics. American Physical Society. https://doi.org/10.1103/revmodphys.91.035005
chicago: Koch, Christiane P., Mikhail Lemeshko, and Dominique Sugny. “Quantum Control
of Molecular Rotation.” Reviews of Modern Physics. American Physical Society,
2019. https://doi.org/10.1103/revmodphys.91.035005.
ieee: C. P. Koch, M. Lemeshko, and D. Sugny, “Quantum control of molecular rotation,”
Reviews of Modern Physics, vol. 91, no. 3. American Physical Society, 2019.
ista: Koch CP, Lemeshko M, Sugny D. 2019. Quantum control of molecular rotation.
Reviews of Modern Physics. 91(3), 035005.
mla: Koch, Christiane P., et al. “Quantum Control of Molecular Rotation.” Reviews
of Modern Physics, vol. 91, no. 3, 035005, American Physical Society, 2019,
doi:10.1103/revmodphys.91.035005.
short: C.P. Koch, M. Lemeshko, D. Sugny, Reviews of Modern Physics 91 (2019).
date_created: 2020-01-29T16:04:19Z
date_published: 2019-09-18T00:00:00Z
date_updated: 2024-02-28T13:15:33Z
day: '18'
department:
- _id: MiLe
doi: 10.1103/revmodphys.91.035005
external_id:
arxiv:
- '1810.11338'
isi:
- '000486661700001'
intvolume: ' 91'
isi: 1
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1810.11338
month: '09'
oa: 1
oa_version: Preprint
project:
- _id: 26031614-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P29902
name: Quantum rotations in the presence of a many-body environment
publication: Reviews of Modern Physics
publication_identifier:
eissn:
- 1539-0756
issn:
- 0034-6861
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Quantum control of molecular rotation
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 91
year: '2019'
...
---
_id: '7397'
abstract:
- lang: eng
text: Polymer additives can substantially reduce the drag of turbulent flows and
the upperlimit, the so called “maximum drag reduction” (MDR) asymptote is universal,
i.e. inde-pendent of the type of polymer and solvent used. Until recently, the
consensus was that,in this limit, flows are in a marginal state where only a minimal
level of turbulence activ-ity persists. Observations in direct numerical simulations
using minimal sized channelsappeared to support this view and reported long “hibernation” periods where turbu-lence
is marginalized. In simulations of pipe flow we find that, indeed, with increasingWeissenberg
number (Wi), turbulence expresses long periods of hibernation if the domainsize
is small. However, with increasing pipe length, the temporal hibernation continuouslyalters
to spatio-temporal intermittency and here the flow consists of turbulent puffs
sur-rounded by laminar flow. Moreover, upon an increase in Wi, the flow fully
relaminarises,in agreement with recent experiments. At even larger Wi, a different
instability is en-countered causing a drag increase towards MDR. Our findings
hence link earlier minimalflow unit simulations with recent experiments and confirm
that the addition of polymersinitially suppresses Newtonian turbulence and leads
to a reverse transition. The MDRstate on the other hand results from a separate
instability and the underlying dynamicscorresponds to the recently proposed state
of elasto-inertial-turbulence (EIT).
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Jose M
full_name: Lopez Alonso, Jose M
id: 40770848-F248-11E8-B48F-1D18A9856A87
last_name: Lopez Alonso
orcid: 0000-0002-0384-2022
- first_name: George H
full_name: Choueiri, George H
id: 448BD5BC-F248-11E8-B48F-1D18A9856A87
last_name: Choueiri
- first_name: Björn
full_name: Hof, Björn
id: 3A374330-F248-11E8-B48F-1D18A9856A87
last_name: Hof
orcid: 0000-0003-2057-2754
citation:
ama: Lopez Alonso JM, Choueiri GH, Hof B. Dynamics of viscoelastic pipe flow at
low Reynolds numbers in the maximum drag reduction limit. Journal of Fluid
Mechanics. 2019;874:699-719. doi:10.1017/jfm.2019.486
apa: Lopez Alonso, J. M., Choueiri, G. H., & Hof, B. (2019). Dynamics of viscoelastic
pipe flow at low Reynolds numbers in the maximum drag reduction limit. Journal
of Fluid Mechanics. CUP. https://doi.org/10.1017/jfm.2019.486
chicago: Lopez Alonso, Jose M, George H Choueiri, and Björn Hof. “Dynamics of Viscoelastic
Pipe Flow at Low Reynolds Numbers in the Maximum Drag Reduction Limit.” Journal
of Fluid Mechanics. CUP, 2019. https://doi.org/10.1017/jfm.2019.486.
ieee: J. M. Lopez Alonso, G. H. Choueiri, and B. Hof, “Dynamics of viscoelastic
pipe flow at low Reynolds numbers in the maximum drag reduction limit,” Journal
of Fluid Mechanics, vol. 874. CUP, pp. 699–719, 2019.
ista: Lopez Alonso JM, Choueiri GH, Hof B. 2019. Dynamics of viscoelastic pipe flow
at low Reynolds numbers in the maximum drag reduction limit. Journal of Fluid
Mechanics. 874, 699–719.
mla: Lopez Alonso, Jose M., et al. “Dynamics of Viscoelastic Pipe Flow at Low Reynolds
Numbers in the Maximum Drag Reduction Limit.” Journal of Fluid Mechanics,
vol. 874, CUP, 2019, pp. 699–719, doi:10.1017/jfm.2019.486.
short: J.M. Lopez Alonso, G.H. Choueiri, B. Hof, Journal of Fluid Mechanics 874
(2019) 699–719.
date_created: 2020-01-29T16:05:19Z
date_published: 2019-09-10T00:00:00Z
date_updated: 2023-09-06T15:36:36Z
day: '10'
department:
- _id: BjHo
doi: 10.1017/jfm.2019.486
external_id:
arxiv:
- '1808.04080'
isi:
- '000475349900001'
intvolume: ' 874'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1808.04080
month: '09'
oa: 1
oa_version: Preprint
page: 699-719
publication: Journal of Fluid Mechanics
publication_identifier:
eissn:
- 1469-7645
issn:
- 0022-1120
publication_status: published
publisher: CUP
quality_controlled: '1'
scopus_import: '1'
status: public
title: Dynamics of viscoelastic pipe flow at low Reynolds numbers in the maximum drag
reduction limit
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 874
year: '2019'
...
---
_id: '7398'
abstract:
- lang: eng
text: 'Transporters of the solute carrier 6 (SLC6) family translocate their cognate
substrate together with Na+ and Cl−. Detailed kinetic models exist for the transporters
of GABA (GAT1/SLC6A1) and the monoamines dopamine (DAT/SLC6A3) and serotonin (SERT/SLC6A4).
Here, we posited that the transport cycle of individual SLC6 transporters reflects
the physiological requirements they operate under. We tested this hypothesis by
analyzing the transport cycle of glycine transporter 1 (GlyT1/SLC6A9) and glycine
transporter 2 (GlyT2/SLC6A5). GlyT2 is the only SLC6 family member known to translocate
glycine, Na+, and Cl− in a 1:3:1 stoichiometry. We analyzed partial reactions
in real time by electrophysiological recordings. Contrary to monoamine transporters,
both GlyTs were found to have a high transport capacity driven by rapid return
of the empty transporter after release of Cl− on the intracellular side. Rapid
cycling of both GlyTs was further supported by highly cooperative binding of cosubstrate
ions and substrate such that their forward transport mode was maintained even
under conditions of elevated intracellular Na+ or Cl−. The most important differences
in the transport cycle of GlyT1 and GlyT2 arose from the kinetics of charge movement
and the resulting voltage-dependent rate-limiting reactions: the kinetics of GlyT1
were governed by transition of the substrate-bound transporter from outward- to
inward-facing conformations, whereas the kinetics of GlyT2 were governed by Na+
binding (or a related conformational change). Kinetic modeling showed that the
kinetics of GlyT1 are ideally suited for supplying the extracellular glycine levels
required for NMDA receptor activation.'
article_processing_charge: No
article_type: original
author:
- first_name: Fatma Asli
full_name: Erdem, Fatma Asli
last_name: Erdem
- first_name: Marija
full_name: Ilic, Marija
last_name: Ilic
- first_name: Peter
full_name: Koppensteiner, Peter
id: 3B8B25A8-F248-11E8-B48F-1D18A9856A87
last_name: Koppensteiner
orcid: 0000-0002-3509-1948
- first_name: Jakub
full_name: Gołacki, Jakub
last_name: Gołacki
- first_name: Gert
full_name: Lubec, Gert
last_name: Lubec
- first_name: Michael
full_name: Freissmuth, Michael
last_name: Freissmuth
- first_name: Walter
full_name: Sandtner, Walter
last_name: Sandtner
citation:
ama: Erdem FA, Ilic M, Koppensteiner P, et al. A comparison of the transport kinetics
of glycine transporter 1 and glycine transporter 2. The Journal of General
Physiology. 2019;151(8):1035-1050. doi:10.1085/jgp.201912318
apa: Erdem, F. A., Ilic, M., Koppensteiner, P., Gołacki, J., Lubec, G., Freissmuth,
M., & Sandtner, W. (2019). A comparison of the transport kinetics of glycine
transporter 1 and glycine transporter 2. The Journal of General Physiology.
Rockefeller University Press. https://doi.org/10.1085/jgp.201912318
chicago: Erdem, Fatma Asli, Marija Ilic, Peter Koppensteiner, Jakub Gołacki, Gert
Lubec, Michael Freissmuth, and Walter Sandtner. “A Comparison of the Transport
Kinetics of Glycine Transporter 1 and Glycine Transporter 2.” The Journal of
General Physiology. Rockefeller University Press, 2019. https://doi.org/10.1085/jgp.201912318.
ieee: F. A. Erdem et al., “A comparison of the transport kinetics of glycine
transporter 1 and glycine transporter 2,” The Journal of General Physiology,
vol. 151, no. 8. Rockefeller University Press, pp. 1035–1050, 2019.
ista: Erdem FA, Ilic M, Koppensteiner P, Gołacki J, Lubec G, Freissmuth M, Sandtner
W. 2019. A comparison of the transport kinetics of glycine transporter 1 and glycine
transporter 2. The Journal of General Physiology. 151(8), 1035–1050.
mla: Erdem, Fatma Asli, et al. “A Comparison of the Transport Kinetics of Glycine
Transporter 1 and Glycine Transporter 2.” The Journal of General Physiology,
vol. 151, no. 8, Rockefeller University Press, 2019, pp. 1035–50, doi:10.1085/jgp.201912318.
short: F.A. Erdem, M. Ilic, P. Koppensteiner, J. Gołacki, G. Lubec, M. Freissmuth,
W. Sandtner, The Journal of General Physiology 151 (2019) 1035–1050.
date_created: 2020-01-29T16:06:29Z
date_published: 2019-07-03T00:00:00Z
date_updated: 2023-09-07T14:52:23Z
day: '03'
ddc:
- '570'
department:
- _id: RySh
doi: 10.1085/jgp.201912318
external_id:
isi:
- '000478792500008'
pmid:
- '31270129'
file:
- access_level: open_access
checksum: 5706b4ccd74ee3e50bf7ecb2a203df71
content_type: application/pdf
creator: dernst
date_created: 2020-02-05T07:20:32Z
date_updated: 2020-07-14T12:47:57Z
file_id: '7450'
file_name: 2019_JGP_Erdem.pdf
file_size: 2641297
relation: main_file
file_date_updated: 2020-07-14T12:47:57Z
has_accepted_license: '1'
intvolume: ' 151'
isi: 1
issue: '8'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: 1035-1050
pmid: 1
publication: The Journal of General Physiology
publication_identifier:
eissn:
- 1540-7748
issn:
- 0022-1295
publication_status: published
publisher: Rockefeller University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: A comparison of the transport kinetics of glycine transporter 1 and glycine
transporter 2
tmp:
image: /images/cc_by_nc_sa.png
legal_code_url: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC
BY-NC-SA 4.0)
short: CC BY-NC-SA (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 151
year: '2019'
...