---
_id: '11966'
abstract:
- lang: eng
text: The front cover artwork is provided by the group of Dr. Bartholomäus Pieber
at the Max Planck Institute of Colloids and Interfaces (Germany). The image symbolizes
the activation of a heterogeneous photocatalyst by visible light and its application
for organic synthesis. Read the full text of the Review at 10.1002/cptc.202000014.
article_processing_charge: No
article_type: original
author:
- first_name: Sebastian
full_name: Gisbertz, Sebastian
last_name: Gisbertz
- first_name: Bartholomäus
full_name: Pieber, Bartholomäus
id: 93e5e5b2-0da6-11ed-8a41-af589a024726
last_name: Pieber
orcid: 0000-0001-8689-388X
citation:
ama: Gisbertz S, Pieber B. Heterogeneous photocatalysis in organic synthesis. ChemPhotoChem.
2020;4(7):454-454. doi:10.1002/cptc.202000137
apa: Gisbertz, S., & Pieber, B. (2020). Heterogeneous photocatalysis in organic
synthesis. ChemPhotoChem. Wiley. https://doi.org/10.1002/cptc.202000137
chicago: Gisbertz, Sebastian, and Bartholomäus Pieber. “Heterogeneous Photocatalysis
in Organic Synthesis.” ChemPhotoChem. Wiley, 2020. https://doi.org/10.1002/cptc.202000137.
ieee: S. Gisbertz and B. Pieber, “Heterogeneous photocatalysis in organic synthesis,”
ChemPhotoChem, vol. 4, no. 7. Wiley, pp. 454–454, 2020.
ista: Gisbertz S, Pieber B. 2020. Heterogeneous photocatalysis in organic synthesis.
ChemPhotoChem. 4(7), 454–454.
mla: Gisbertz, Sebastian, and Bartholomäus Pieber. “Heterogeneous Photocatalysis
in Organic Synthesis.” ChemPhotoChem, vol. 4, no. 7, Wiley, 2020, pp. 454–454,
doi:10.1002/cptc.202000137.
short: S. Gisbertz, B. Pieber, ChemPhotoChem 4 (2020) 454–454.
date_created: 2022-08-25T08:33:38Z
date_published: 2020-07-01T00:00:00Z
date_updated: 2023-02-21T10:09:40Z
day: '01'
doi: 10.1002/cptc.202000137
extern: '1'
intvolume: ' 4'
issue: '7'
language:
- iso: eng
month: '07'
oa_version: None
page: 454-454
publication: ChemPhotoChem
publication_identifier:
eissn:
- 2367-0932
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Heterogeneous photocatalysis in organic synthesis
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 4
year: '2020'
...
---
_id: '11969'
abstract:
- lang: eng
text: Photochemistry enables new synthetic means to form carbon–heteroatom bonds.
Photocatalysts can catalyze carbon–heteroatom cross-couplings by electron or energy
transfer either alone or in combination with a second catalyst. Photocatalyst-free
methods are possible using photolabile substrates or by generating photoactive
electron donor-acceptor complexes. This review summarizes and discusses the strategies
used in light-mediated carbon–heteroatom bond formations based on the proposed
mechanisms.
article_processing_charge: No
article_type: review
author:
- first_name: Cristian
full_name: Cavedon, Cristian
last_name: Cavedon
- first_name: Peter H.
full_name: Seeberger, Peter H.
last_name: Seeberger
- first_name: Bartholomäus
full_name: Pieber, Bartholomäus
id: 93e5e5b2-0da6-11ed-8a41-af589a024726
last_name: Pieber
orcid: 0000-0001-8689-388X
citation:
ama: Cavedon C, Seeberger PH, Pieber B. Photochemical strategies for carbon–heteroatom
bond formation. European Journal of Organic Chemistry. 2020;2020(10):1379-1392.
doi:10.1002/ejoc.201901173
apa: Cavedon, C., Seeberger, P. H., & Pieber, B. (2020). Photochemical strategies
for carbon–heteroatom bond formation. European Journal of Organic Chemistry.
Wiley. https://doi.org/10.1002/ejoc.201901173
chicago: Cavedon, Cristian, Peter H. Seeberger, and Bartholomäus Pieber. “Photochemical
Strategies for Carbon–Heteroatom Bond Formation.” European Journal of Organic
Chemistry. Wiley, 2020. https://doi.org/10.1002/ejoc.201901173.
ieee: C. Cavedon, P. H. Seeberger, and B. Pieber, “Photochemical strategies for
carbon–heteroatom bond formation,” European Journal of Organic Chemistry,
vol. 2020, no. 10. Wiley, pp. 1379–1392, 2020.
ista: Cavedon C, Seeberger PH, Pieber B. 2020. Photochemical strategies for carbon–heteroatom
bond formation. European Journal of Organic Chemistry. 2020(10), 1379–1392.
mla: Cavedon, Cristian, et al. “Photochemical Strategies for Carbon–Heteroatom Bond
Formation.” European Journal of Organic Chemistry, vol. 2020, no. 10, Wiley,
2020, pp. 1379–92, doi:10.1002/ejoc.201901173.
short: C. Cavedon, P.H. Seeberger, B. Pieber, European Journal of Organic Chemistry
2020 (2020) 1379–1392.
date_created: 2022-08-25T08:49:25Z
date_published: 2020-03-15T00:00:00Z
date_updated: 2023-02-21T10:09:47Z
day: '15'
doi: 10.1002/ejoc.201901173
extern: '1'
intvolume: ' 2020'
issue: '10'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1002/ejoc.201901173
month: '03'
oa: 1
oa_version: Published Version
page: 1379-1392
publication: European Journal of Organic Chemistry
publication_identifier:
eissn:
- 1099-0690
issn:
- 1434-193X
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Photochemical strategies for carbon–heteroatom bond formation
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2020
year: '2020'
...
---
_id: '11978'
abstract:
- lang: eng
text: Dual photocatalysis and nickel catalysis can effect cross-coupling under mild
conditions, but little is known about the in situ kinetics of this class of reactions.
We report a comprehensive kinetic examination of a model carboxylate O-arylation,
comparing a state-of-the-art homogeneous photocatalyst (Ir(ppy)3) with a competitive
heterogeneous photocatalyst (graphitic carbon nitride). Experimental conditions
were adjusted such that the nickel catalytic cycle is saturated with excited photocatalyst.
This approach was designed to remove the role of the photocatalyst, by which only
the intrinsic behaviors of the nickel catalytic cycles are observed. The two reactions
did not display identical kinetics. Ir(ppy)3 deactivates the nickel catalytic
cycle and creates more dehalogenated side product. Kinetic data for the reaction
using Ir(ppy)3 supports a turnover-limiting reductive elimination. Graphitic carbon
nitride gave higher selectivity, even at high photocatalyst-to-nickel ratios.
The heterogeneous reaction also showed a rate dependence on aryl halide, indicating
that oxidative addition plays a role in rate determination. The results argue
against the current mechanistic hypothesis, which states that the photocatalyst
is only involved to trigger reductive elimination.
article_processing_charge: No
article_type: original
author:
- first_name: Jamal A.
full_name: Malik, Jamal A.
last_name: Malik
- first_name: Amiera
full_name: Madani, Amiera
last_name: Madani
- first_name: Bartholomäus
full_name: Pieber, Bartholomäus
id: 93e5e5b2-0da6-11ed-8a41-af589a024726
last_name: Pieber
orcid: 0000-0001-8689-388X
- first_name: Peter H.
full_name: Seeberger, Peter H.
last_name: Seeberger
citation:
ama: Malik JA, Madani A, Pieber B, Seeberger PH. Evidence for photocatalyst involvement
in oxidative additions of nickel-catalyzed carboxylate O-arylations. Journal
of the American Chemical Society. 2020;142(25):11042-11049. doi:10.1021/jacs.0c02848
apa: Malik, J. A., Madani, A., Pieber, B., & Seeberger, P. H. (2020). Evidence
for photocatalyst involvement in oxidative additions of nickel-catalyzed carboxylate
O-arylations. Journal of the American Chemical Society. American Chemical
Society. https://doi.org/10.1021/jacs.0c02848
chicago: Malik, Jamal A., Amiera Madani, Bartholomäus Pieber, and Peter H. Seeberger.
“Evidence for Photocatalyst Involvement in Oxidative Additions of Nickel-Catalyzed
Carboxylate O-Arylations.” Journal of the American Chemical Society. American
Chemical Society, 2020. https://doi.org/10.1021/jacs.0c02848.
ieee: J. A. Malik, A. Madani, B. Pieber, and P. H. Seeberger, “Evidence for photocatalyst
involvement in oxidative additions of nickel-catalyzed carboxylate O-arylations,”
Journal of the American Chemical Society, vol. 142, no. 25. American Chemical
Society, pp. 11042–11049, 2020.
ista: Malik JA, Madani A, Pieber B, Seeberger PH. 2020. Evidence for photocatalyst
involvement in oxidative additions of nickel-catalyzed carboxylate O-arylations.
Journal of the American Chemical Society. 142(25), 11042–11049.
mla: Malik, Jamal A., et al. “Evidence for Photocatalyst Involvement in Oxidative
Additions of Nickel-Catalyzed Carboxylate O-Arylations.” Journal of the American
Chemical Society, vol. 142, no. 25, American Chemical Society, 2020, pp. 11042–49,
doi:10.1021/jacs.0c02848.
short: J.A. Malik, A. Madani, B. Pieber, P.H. Seeberger, Journal of the American
Chemical Society 142 (2020) 11042–11049.
date_created: 2022-08-25T10:57:38Z
date_published: 2020-06-24T00:00:00Z
date_updated: 2023-02-21T10:10:06Z
day: '24'
doi: 10.1021/jacs.0c02848
extern: '1'
external_id:
pmid:
- '32469219'
intvolume: ' 142'
issue: '25'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1021/jacs.0c02848
month: '06'
oa: 1
oa_version: Published Version
page: 11042-11049
pmid: 1
publication: Journal of the American Chemical Society
publication_identifier:
eissn:
- 1520-5126
issn:
- 0002-7863
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Evidence for photocatalyst involvement in oxidative additions of nickel-catalyzed
carboxylate O-arylations
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 142
year: '2020'
...
---
_id: '11979'
abstract:
- lang: eng
text: Dual photoredox/nickel-catalysed C–N cross-couplings suffer from low yields
for electron-rich aryl halides. The formation of catalytically inactive nickel-black
is responsible for this limitation and causes severe reproducibility issues. Here,
we demonstrate that catalyst deactivation can be avoided by using a carbon nitride
photocatalyst. The broad absorption of the heterogeneous photocatalyst enables
wavelength-dependent control of the rate of reductive elimination to prevent nickel-black
formation during the coupling of cyclic, secondary amines and aryl halides. A
second approach, which is applicable to a broader set of electron-rich aryl halides,
is to run the reactions at high concentrations to increase the rate of oxidative
addition. Less nucleophilic, primary amines can be coupled with electron-rich
aryl halides by stabilizing low-valent nickel intermediates with a suitable additive.
The developed protocols enable reproducible, selective C–N cross-couplings of
electron-rich aryl bromides and can also be applied for electron-poor aryl chlorides.
article_processing_charge: No
article_type: original
author:
- first_name: Sebastian
full_name: Gisbertz, Sebastian
last_name: Gisbertz
- first_name: Susanne
full_name: Reischauer, Susanne
last_name: Reischauer
- first_name: Bartholomäus
full_name: Pieber, Bartholomäus
id: 93e5e5b2-0da6-11ed-8a41-af589a024726
last_name: Pieber
orcid: 0000-0001-8689-388X
citation:
ama: Gisbertz S, Reischauer S, Pieber B. Overcoming limitations in dual photoredox/nickel-catalysed
C–N cross-couplings due to catalyst deactivation. Nature Catalysis. 2020;3(8):611-620.
doi:10.1038/s41929-020-0473-6
apa: Gisbertz, S., Reischauer, S., & Pieber, B. (2020). Overcoming limitations
in dual photoredox/nickel-catalysed C–N cross-couplings due to catalyst deactivation.
Nature Catalysis. Springer Nature. https://doi.org/10.1038/s41929-020-0473-6
chicago: Gisbertz, Sebastian, Susanne Reischauer, and Bartholomäus Pieber. “Overcoming
Limitations in Dual Photoredox/Nickel-Catalysed C–N Cross-Couplings Due to Catalyst
Deactivation.” Nature Catalysis. Springer Nature, 2020. https://doi.org/10.1038/s41929-020-0473-6.
ieee: S. Gisbertz, S. Reischauer, and B. Pieber, “Overcoming limitations in dual
photoredox/nickel-catalysed C–N cross-couplings due to catalyst deactivation,”
Nature Catalysis, vol. 3, no. 8. Springer Nature, pp. 611–620, 2020.
ista: Gisbertz S, Reischauer S, Pieber B. 2020. Overcoming limitations in dual photoredox/nickel-catalysed
C–N cross-couplings due to catalyst deactivation. Nature Catalysis. 3(8), 611–620.
mla: Gisbertz, Sebastian, et al. “Overcoming Limitations in Dual Photoredox/Nickel-Catalysed
C–N Cross-Couplings Due to Catalyst Deactivation.” Nature Catalysis, vol.
3, no. 8, Springer Nature, 2020, pp. 611–20, doi:10.1038/s41929-020-0473-6.
short: S. Gisbertz, S. Reischauer, B. Pieber, Nature Catalysis 3 (2020) 611–620.
date_created: 2022-08-25T11:06:16Z
date_published: 2020-08-01T00:00:00Z
date_updated: 2023-02-21T10:10:09Z
day: '01'
doi: 10.1038/s41929-020-0473-6
extern: '1'
intvolume: ' 3'
issue: '8'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.26434/chemrxiv.10298735
month: '08'
oa: 1
oa_version: Preprint
page: 611-620
publication: Nature Catalysis
publication_identifier:
eissn:
- 2520-1158
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Overcoming limitations in dual photoredox/nickel-catalysed C–N cross-couplings
due to catalyst deactivation
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 3
year: '2020'
...
---
_id: '11980'
abstract:
- lang: eng
text: Small organic radicals are ubiquitous intermediates in photocatalysis and
are used in organic synthesis to install functional groups and to tune electronic
properties and pharmacokinetic parameters of the final molecule. Development of
new methods to generate small organic radicals with added functionality can further
extend the utility of photocatalysis for synthetic needs. Herein, we present a
method to generate dichloromethyl radicals from chloroform using a heterogeneous
potassium poly(heptazine imide) (K-PHI) photocatalyst under visible light irradiation
for C1-extension of the enone backbone. The method is applied on 15 enones, with
γ,γ-dichloroketones yields of 18–89%. Due to negative zeta-potential (−40 mV)
and small particle size (100 nm) K-PHI suspension is used in quasi-homogeneous
flow-photoreactor increasing the productivity by 19 times compared to the batch
approach. The resulting γ,γ-dichloroketones, are used as bifunctional building
blocks to access value-added organic compounds such as substituted furans and
pyrroles.
article_number: '1387'
article_processing_charge: No
article_type: original
author:
- first_name: Stefano
full_name: Mazzanti, Stefano
last_name: Mazzanti
- first_name: Bogdan
full_name: Kurpil, Bogdan
last_name: Kurpil
- first_name: Bartholomäus
full_name: Pieber, Bartholomäus
id: 93e5e5b2-0da6-11ed-8a41-af589a024726
last_name: Pieber
orcid: 0000-0001-8689-388X
- first_name: Markus
full_name: Antonietti, Markus
last_name: Antonietti
- first_name: Aleksandr
full_name: Savateev, Aleksandr
last_name: Savateev
citation:
ama: Mazzanti S, Kurpil B, Pieber B, Antonietti M, Savateev A. Dichloromethylation
of enones by carbon nitride photocatalysis. Nature Communications. 2020;11.
doi:10.1038/s41467-020-15131-0
apa: Mazzanti, S., Kurpil, B., Pieber, B., Antonietti, M., & Savateev, A. (2020).
Dichloromethylation of enones by carbon nitride photocatalysis. Nature Communications.
Springer Nature. https://doi.org/10.1038/s41467-020-15131-0
chicago: Mazzanti, Stefano, Bogdan Kurpil, Bartholomäus Pieber, Markus Antonietti,
and Aleksandr Savateev. “Dichloromethylation of Enones by Carbon Nitride Photocatalysis.”
Nature Communications. Springer Nature, 2020. https://doi.org/10.1038/s41467-020-15131-0.
ieee: S. Mazzanti, B. Kurpil, B. Pieber, M. Antonietti, and A. Savateev, “Dichloromethylation
of enones by carbon nitride photocatalysis,” Nature Communications, vol.
11. Springer Nature, 2020.
ista: Mazzanti S, Kurpil B, Pieber B, Antonietti M, Savateev A. 2020. Dichloromethylation
of enones by carbon nitride photocatalysis. Nature Communications. 11, 1387.
mla: Mazzanti, Stefano, et al. “Dichloromethylation of Enones by Carbon Nitride
Photocatalysis.” Nature Communications, vol. 11, 1387, Springer Nature,
2020, doi:10.1038/s41467-020-15131-0.
short: S. Mazzanti, B. Kurpil, B. Pieber, M. Antonietti, A. Savateev, Nature Communications
11 (2020).
date_created: 2022-08-25T11:10:15Z
date_published: 2020-03-13T00:00:00Z
date_updated: 2023-02-21T10:10:14Z
day: '13'
doi: 10.1038/s41467-020-15131-0
extern: '1'
intvolume: ' 11'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1038/s41467-020-15131-0
month: '03'
oa: 1
oa_version: Published Version
publication: Nature Communications
publication_identifier:
eissn:
- 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Dichloromethylation of enones by carbon nitride photocatalysis
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 11
year: '2020'
...
---
_id: '11986'
abstract:
- lang: eng
text: Carbon nitride materials have emerged as an efficient and sustainable class
of heterogeneous photocatalysts, particularly when paired with nickel in dual
catalytic cross-coupling reactions. Performing these transformations on larger
scales using a continuous process is difficult due to the problems associated
with handling solids in flow. By combining an oscillatory pump with a microstructured
plug flow photoreactor, a stable suspension of the photocatalyst can be maintained,
circumventing clogging of the reactor channels. Through careful tuning of the
oscillator properties, the residence time distribution (RTD) was optimized, whilst
maintaining a stable catalyst suspension. Short residence times (20 min) were
achieved using optimized conditions and the recyclability of the photocatalyst
was demonstrated over 10 cycles with no loss of activity. During a stable 4.5
hour scale-out demonstration, the model substrate could be isolated on 12 g scale
(90% yield, 2.67 g h−1). Moreover, the method was applied for the gram scale synthesis
of an intermediate of the active pharmaceutical ingredient tetracaine.
article_processing_charge: No
article_type: original
author:
- first_name: Cristian
full_name: Rosso, Cristian
last_name: Rosso
- first_name: Sebastian
full_name: Gisbertz, Sebastian
last_name: Gisbertz
- first_name: Jason D.
full_name: Williams, Jason D.
last_name: Williams
- first_name: Hannes P. L.
full_name: Gemoets, Hannes P. L.
last_name: Gemoets
- first_name: Wouter
full_name: Debrouwer, Wouter
last_name: Debrouwer
- first_name: Bartholomäus
full_name: Pieber, Bartholomäus
id: 93e5e5b2-0da6-11ed-8a41-af589a024726
last_name: Pieber
orcid: 0000-0001-8689-388X
- first_name: C. Oliver
full_name: Kappe, C. Oliver
last_name: Kappe
citation:
ama: Rosso C, Gisbertz S, Williams JD, et al. An oscillatory plug flow photoreactor
facilitates semi-heterogeneous dual nickel/carbon nitride photocatalytic C–N couplings.
Reaction Chemistry and Engineering. 2020;5(3):597-604. doi:10.1039/d0re00036a
apa: Rosso, C., Gisbertz, S., Williams, J. D., Gemoets, H. P. L., Debrouwer, W.,
Pieber, B., & Kappe, C. O. (2020). An oscillatory plug flow photoreactor facilitates
semi-heterogeneous dual nickel/carbon nitride photocatalytic C–N couplings. Reaction
Chemistry and Engineering. Royal Society of Chemistry. https://doi.org/10.1039/d0re00036a
chicago: Rosso, Cristian, Sebastian Gisbertz, Jason D. Williams, Hannes P. L. Gemoets,
Wouter Debrouwer, Bartholomäus Pieber, and C. Oliver Kappe. “An Oscillatory Plug
Flow Photoreactor Facilitates Semi-Heterogeneous Dual Nickel/Carbon Nitride Photocatalytic
C–N Couplings.” Reaction Chemistry and Engineering. Royal Society of Chemistry,
2020. https://doi.org/10.1039/d0re00036a.
ieee: C. Rosso et al., “An oscillatory plug flow photoreactor facilitates
semi-heterogeneous dual nickel/carbon nitride photocatalytic C–N couplings,” Reaction
Chemistry and Engineering, vol. 5, no. 3. Royal Society of Chemistry, pp.
597–604, 2020.
ista: Rosso C, Gisbertz S, Williams JD, Gemoets HPL, Debrouwer W, Pieber B, Kappe
CO. 2020. An oscillatory plug flow photoreactor facilitates semi-heterogeneous
dual nickel/carbon nitride photocatalytic C–N couplings. Reaction Chemistry and
Engineering. 5(3), 597–604.
mla: Rosso, Cristian, et al. “An Oscillatory Plug Flow Photoreactor Facilitates
Semi-Heterogeneous Dual Nickel/Carbon Nitride Photocatalytic C–N Couplings.” Reaction
Chemistry and Engineering, vol. 5, no. 3, Royal Society of Chemistry, 2020,
pp. 597–604, doi:10.1039/d0re00036a.
short: C. Rosso, S. Gisbertz, J.D. Williams, H.P.L. Gemoets, W. Debrouwer, B. Pieber,
C.O. Kappe, Reaction Chemistry and Engineering 5 (2020) 597–604.
date_created: 2022-08-25T11:45:02Z
date_published: 2020-03-01T00:00:00Z
date_updated: 2023-02-21T10:10:28Z
day: '01'
doi: 10.1039/d0re00036a
extern: '1'
intvolume: ' 5'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1039/D0RE00036A
month: '03'
oa: 1
oa_version: Published Version
page: 597-604
publication: Reaction Chemistry and Engineering
publication_identifier:
eissn:
- 2058-9883
publication_status: published
publisher: Royal Society of Chemistry
quality_controlled: '1'
scopus_import: '1'
status: public
title: An oscillatory plug flow photoreactor facilitates semi-heterogeneous dual nickel/carbon
nitride photocatalytic C–N couplings
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2020'
...
---
_id: '12188'
abstract:
- lang: eng
text: Molecular mechanisms enabling the switching and maintenance of epigenetic
states are not fully understood. Distinct histone modifications are often associated
with ON/OFF epigenetic states, but how these states are stably maintained through
DNA replication, yet in certain situations switch from one to another remains
unclear. Here, we address this problem through identification of Arabidopsis INCURVATA11
(ICU11) as a Polycomb Repressive Complex 2 accessory protein. ICU11 robustly immunoprecipitated
in vivo with PRC2 core components and the accessory proteins, EMBRYONIC FLOWER
1 (EMF1), LIKE HETEROCHROMATIN PROTEIN1 (LHP1), and TELOMERE_REPEAT_BINDING FACTORS
(TRBs). ICU11 encodes a 2-oxoglutarate-dependent dioxygenase, an activity associated
with histone demethylation in other organisms, and mutant plants show defects
in multiple aspects of the Arabidopsis epigenome. To investigate its primary molecular
function we identified the Arabidopsis FLOWERING LOCUS C (FLC) as a direct target
and found icu11 disrupted the cold-induced, Polycomb-mediated silencing underlying
vernalization. icu11 prevented reduction in H3K36me3 levels normally seen during
the early cold phase, supporting a role for ICU11 in H3K36me3 demethylation. This
was coincident with an attenuation of H3K27me3 at the internal nucleation site
in FLC, and reduction in H3K27me3 levels across the body of the gene after plants
were returned to the warm. Thus, ICU11 is required for the cold-induced epigenetic
switching between the mutually exclusive chromatin states at FLC, from the active
H3K36me3 state to the silenced H3K27me3 state. These data support the importance
of physical coupling of histone modification activities to promote epigenetic
switching between opposing chromatin states.
acknowledgement: We would like to thank Scott Berry for help with ICU-GFP nuclear
localization microscopy, Hao Yu and Lisha Shen for assistance with 6mA DNA methylation
analysis, Donna Gibson for graphic design assistance, and members of the C.D. and
Howard laboratories for helpful discussions. This work was funded by the European
Research Council grants to “MEXTIM” (to C.D.) and “SexMeth” (to X. Feng), by the
Biotechnological and Biological Sciences Research Council (BBSRC) Institute Strategic
Programmes GRO (BB/J004588/1), GEN (BB/P013511/1), BBSRC grant (to X. Feng) (BB/S009620/1),
and the Marie Sklodowska–Curie Postdoctoral Fellowships “UNRAVEL” (to R.H.B.) and
"WISDOM" (to X. Fang). Additional funding via the Wellcome Trust through a Senior
Research Fellowship (to J.R.) (103139) and a multiuser equipment grant (108504).
The Wellcome Centre for Cell Biology is supported by core funding from the Wellcome
Trust (203149).
article_processing_charge: No
article_type: original
author:
- first_name: Rebecca H.
full_name: Bloomer, Rebecca H.
last_name: Bloomer
- first_name: Claire E.
full_name: Hutchison, Claire E.
last_name: Hutchison
- first_name: Isabel
full_name: Bäurle, Isabel
last_name: Bäurle
- first_name: James
full_name: Walker, James
last_name: Walker
- first_name: Xiaofeng
full_name: Fang, Xiaofeng
last_name: Fang
- first_name: Pumi
full_name: Perera, Pumi
last_name: Perera
- first_name: Christos N.
full_name: Velanis, Christos N.
last_name: Velanis
- first_name: Serin
full_name: Gümüs, Serin
last_name: Gümüs
- first_name: Christos
full_name: Spanos, Christos
last_name: Spanos
- first_name: Juri
full_name: Rappsilber, Juri
last_name: Rappsilber
- first_name: Xiaoqi
full_name: Feng, Xiaoqi
id: e0164712-22ee-11ed-b12a-d80fcdf35958
last_name: Feng
orcid: 0000-0002-4008-1234
- first_name: Justin
full_name: Goodrich, Justin
last_name: Goodrich
- first_name: Caroline
full_name: Dean, Caroline
last_name: Dean
citation:
ama: Bloomer RH, Hutchison CE, Bäurle I, et al. The Arabidopsis epigenetic regulator
ICU11 as an accessory protein of polycomb repressive complex 2. Proceedings
of the National Academy of Sciences. 2020;117(28):16660-16666. doi:10.1073/pnas.1920621117
apa: Bloomer, R. H., Hutchison, C. E., Bäurle, I., Walker, J., Fang, X., Perera,
P., … Dean, C. (2020). The Arabidopsis epigenetic regulator ICU11 as an accessory
protein of polycomb repressive complex 2. Proceedings of the National Academy
of Sciences. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1920621117
chicago: Bloomer, Rebecca H., Claire E. Hutchison, Isabel Bäurle, James Walker,
Xiaofeng Fang, Pumi Perera, Christos N. Velanis, et al. “The Arabidopsis Epigenetic
Regulator ICU11 as an Accessory Protein of Polycomb Repressive Complex 2.” Proceedings
of the National Academy of Sciences. Proceedings of the National Academy of
Sciences, 2020. https://doi.org/10.1073/pnas.1920621117.
ieee: R. H. Bloomer et al., “The Arabidopsis epigenetic regulator ICU11
as an accessory protein of polycomb repressive complex 2,” Proceedings of the
National Academy of Sciences, vol. 117, no. 28. Proceedings of the National
Academy of Sciences, pp. 16660–16666, 2020.
ista: Bloomer RH, Hutchison CE, Bäurle I, Walker J, Fang X, Perera P, Velanis CN,
Gümüs S, Spanos C, Rappsilber J, Feng X, Goodrich J, Dean C. 2020. The Arabidopsis
epigenetic regulator ICU11 as an accessory protein of polycomb repressive complex
2. Proceedings of the National Academy of Sciences. 117(28), 16660–16666.
mla: Bloomer, Rebecca H., et al. “The Arabidopsis Epigenetic Regulator ICU11 as
an Accessory Protein of Polycomb Repressive Complex 2.” Proceedings of the
National Academy of Sciences, vol. 117, no. 28, Proceedings of the National
Academy of Sciences, 2020, pp. 16660–66, doi:10.1073/pnas.1920621117.
short: R.H. Bloomer, C.E. Hutchison, I. Bäurle, J. Walker, X. Fang, P. Perera, C.N.
Velanis, S. Gümüs, C. Spanos, J. Rappsilber, X. Feng, J. Goodrich, C. Dean, Proceedings
of the National Academy of Sciences 117 (2020) 16660–16666.
date_created: 2023-01-16T09:15:44Z
date_published: 2020-05-22T00:00:00Z
date_updated: 2023-05-08T10:53:55Z
day: '22'
ddc:
- '580'
department:
- _id: XiFe
doi: 10.1073/pnas.1920621117
extern: '1'
external_id:
pmid:
- '32601198'
file:
- access_level: open_access
checksum: cedee184cb12f454f2fba4158ff47db9
content_type: application/pdf
creator: alisjak
date_created: 2023-02-07T11:29:55Z
date_updated: 2023-02-07T11:29:55Z
file_id: '12526'
file_name: 2020_PNAS_Bloomer.pdf
file_size: 1105414
relation: main_file
success: 1
file_date_updated: 2023-02-07T11:29:55Z
has_accepted_license: '1'
intvolume: ' 117'
issue: '28'
keyword:
- Multidisciplinary
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368280/
month: '05'
oa: 1
oa_version: Published Version
page: 16660-16666
pmid: 1
publication: Proceedings of the National Academy of Sciences
publication_identifier:
issn:
- 0027-8424
- 1091-6490
publication_status: published
publisher: Proceedings of the National Academy of Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: The Arabidopsis epigenetic regulator ICU11 as an accessory protein of polycomb
repressive complex 2
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 117
year: '2020'
...
---
_id: '12189'
abstract:
- lang: eng
text: Meiotic crossovers (COs) are important for reshuffling genetic information
between homologous chromosomes and they are essential for their correct segregation.
COs are unevenly distributed along chromosomes and the underlying mechanisms controlling
CO localization are not well understood. We previously showed that meiotic COs
are mis-localized in the absence of AXR1, an enzyme involved in the neddylation/rubylation
protein modification pathway in Arabidopsis thaliana. Here, we report that in
axr1-/-, male meiocytes show a strong defect in chromosome pairing whereas the
formation of the telomere bouquet is not affected. COs are also redistributed
towards subtelomeric chromosomal ends where they frequently form clusters, in
contrast to large central regions depleted in recombination. The CO suppressed
regions correlate with DNA hypermethylation of transposable elements (TEs) in
the CHH context in axr1-/- meiocytes. Through examining somatic methylomes, we
found axr1-/- affects DNA methylation in a plant, causing hypermethylation in
all sequence contexts (CG, CHG and CHH) in TEs. Impairment of the main pathways
involved in DNA methylation is epistatic over axr1-/- for DNA methylation in somatic
cells but does not restore regular chromosome segregation during meiosis. Collectively,
our findings reveal that the neddylation pathway not only regulates hormonal perception
and CO distribution but is also, directly or indirectly, a major limiting pathway
of TE DNA methylation in somatic cells.
acknowledgement: The authors wish to thank Cécile Raynaud, Eric Jenczewski, Rajeev
Kumar, Raphaël Mercier and Jean Molinier for critical reading of the manuscript.
article_number: e1008894
article_processing_charge: No
article_type: original
author:
- first_name: Nicolas
full_name: Christophorou, Nicolas
last_name: Christophorou
- first_name: Wenjing
full_name: She, Wenjing
last_name: She
- first_name: Jincheng
full_name: Long, Jincheng
last_name: Long
- first_name: Aurélie
full_name: Hurel, Aurélie
last_name: Hurel
- first_name: Sébastien
full_name: Beaubiat, Sébastien
last_name: Beaubiat
- first_name: Yassir
full_name: Idir, Yassir
last_name: Idir
- first_name: Marina
full_name: Tagliaro-Jahns, Marina
last_name: Tagliaro-Jahns
- first_name: Aurélie
full_name: Chambon, Aurélie
last_name: Chambon
- first_name: Victor
full_name: Solier, Victor
last_name: Solier
- first_name: Daniel
full_name: Vezon, Daniel
last_name: Vezon
- first_name: Mathilde
full_name: Grelon, Mathilde
last_name: Grelon
- first_name: Xiaoqi
full_name: Feng, Xiaoqi
id: e0164712-22ee-11ed-b12a-d80fcdf35958
last_name: Feng
orcid: 0000-0002-4008-1234
- first_name: Nicolas
full_name: Bouché, Nicolas
last_name: Bouché
- first_name: Christine
full_name: Mézard, Christine
last_name: Mézard
citation:
ama: Christophorou N, She W, Long J, et al. AXR1 affects DNA methylation independently
of its role in regulating meiotic crossover localization. PLOS Genetics.
2020;16(6). doi:10.1371/journal.pgen.1008894
apa: Christophorou, N., She, W., Long, J., Hurel, A., Beaubiat, S., Idir, Y., …
Mézard, C. (2020). AXR1 affects DNA methylation independently of its role in regulating
meiotic crossover localization. PLOS Genetics. Public Library of Science
(PLoS). https://doi.org/10.1371/journal.pgen.1008894
chicago: Christophorou, Nicolas, Wenjing She, Jincheng Long, Aurélie Hurel, Sébastien
Beaubiat, Yassir Idir, Marina Tagliaro-Jahns, et al. “AXR1 Affects DNA Methylation
Independently of Its Role in Regulating Meiotic Crossover Localization.” PLOS
Genetics. Public Library of Science (PLoS), 2020. https://doi.org/10.1371/journal.pgen.1008894.
ieee: N. Christophorou et al., “AXR1 affects DNA methylation independently
of its role in regulating meiotic crossover localization,” PLOS Genetics,
vol. 16, no. 6. Public Library of Science (PLoS), 2020.
ista: Christophorou N, She W, Long J, Hurel A, Beaubiat S, Idir Y, Tagliaro-Jahns
M, Chambon A, Solier V, Vezon D, Grelon M, Feng X, Bouché N, Mézard C. 2020. AXR1
affects DNA methylation independently of its role in regulating meiotic crossover
localization. PLOS Genetics. 16(6), e1008894.
mla: Christophorou, Nicolas, et al. “AXR1 Affects DNA Methylation Independently
of Its Role in Regulating Meiotic Crossover Localization.” PLOS Genetics,
vol. 16, no. 6, e1008894, Public Library of Science (PLoS), 2020, doi:10.1371/journal.pgen.1008894.
short: N. Christophorou, W. She, J. Long, A. Hurel, S. Beaubiat, Y. Idir, M. Tagliaro-Jahns,
A. Chambon, V. Solier, D. Vezon, M. Grelon, X. Feng, N. Bouché, C. Mézard, PLOS
Genetics 16 (2020).
date_created: 2023-01-16T09:16:10Z
date_published: 2020-06-29T00:00:00Z
date_updated: 2023-05-08T10:54:39Z
day: '29'
department:
- _id: XiFe
doi: 10.1371/journal.pgen.1008894
extern: '1'
external_id:
pmid:
- '32598340'
intvolume: ' 16'
issue: '6'
keyword:
- Cancer Research
- Genetics (clinical)
- Genetics
- Molecular Biology
- Ecology
- Evolution
- Behavior and Systematics
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351236/
month: '06'
oa: 1
oa_version: Published Version
pmid: 1
publication: PLOS Genetics
publication_identifier:
issn:
- 1553-7404
publication_status: published
publisher: Public Library of Science (PLoS)
quality_controlled: '1'
scopus_import: '1'
status: public
title: AXR1 affects DNA methylation independently of its role in regulating meiotic
crossover localization
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 16
year: '2020'
...
---
_id: '12310'
abstract:
- lang: eng
text: Let be a sequence of points on an elliptic curve defined over a number field
K. In this paper, we study the denominators of the x-coordinates of this sequence.
We prove that, if Q is a torsion point of prime order, then for n large enough
there always exists a primitive divisor. Later on, we show the link between the
study of the primitive divisors and a Lang-Trotter conjecture. Indeed, given two
points P and Q on the elliptic curve, we prove a lower bound for the number of
primes p such that P is in the orbit of Q modulo p.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Matteo
full_name: Verzobio, Matteo
id: 7aa8f170-131e-11ed-88e1-a9efd01027cb
last_name: Verzobio
orcid: 0000-0002-0854-0306
citation:
ama: Verzobio M. Primitive divisors of sequences associated to elliptic curves.
Journal of Number Theory. 2020;209(4):378-390. doi:10.1016/j.jnt.2019.09.003
apa: Verzobio, M. (2020). Primitive divisors of sequences associated to elliptic
curves. Journal of Number Theory. Elsevier. https://doi.org/10.1016/j.jnt.2019.09.003
chicago: Verzobio, Matteo. “Primitive Divisors of Sequences Associated to Elliptic
Curves.” Journal of Number Theory. Elsevier, 2020. https://doi.org/10.1016/j.jnt.2019.09.003.
ieee: M. Verzobio, “Primitive divisors of sequences associated to elliptic curves,”
Journal of Number Theory, vol. 209, no. 4. Elsevier, pp. 378–390, 2020.
ista: Verzobio M. 2020. Primitive divisors of sequences associated to elliptic curves.
Journal of Number Theory. 209(4), 378–390.
mla: Verzobio, Matteo. “Primitive Divisors of Sequences Associated to Elliptic Curves.”
Journal of Number Theory, vol. 209, no. 4, Elsevier, 2020, pp. 378–90,
doi:10.1016/j.jnt.2019.09.003.
short: M. Verzobio, Journal of Number Theory 209 (2020) 378–390.
date_created: 2023-01-16T11:45:07Z
date_published: 2020-04-01T00:00:00Z
date_updated: 2023-05-10T11:14:56Z
day: '01'
doi: 10.1016/j.jnt.2019.09.003
extern: '1'
external_id:
arxiv:
- '1906.00632'
intvolume: ' 209'
issue: '4'
keyword:
- Algebra and Number Theory
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.1906.00632
month: '04'
oa: 1
oa_version: Preprint
page: 378-390
publication: Journal of Number Theory
publication_identifier:
issn:
- 0022-314X
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Primitive divisors of sequences associated to elliptic curves
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 209
year: '2020'
...
---
_id: '12593'
abstract:
- lang: eng
text: 'Rock debris can accumulate on glacier surfaces and dramatically reduce glacier
melt. The structure of a debris cover is unique to each glacier and sensitive
to climate. Despite this, debris cover has been omitted from global glacier models
and forecasts of their response to a changing climate. Fundamental to resolving
these omissions is a global map of debris cover and an estimate of its future
spatial evolution. Here we use Landsat imagery and a detailed correction to the
Randolph Glacier Inventory to show that 7.3% of mountain glacier area is debris
covered and over half of Earth’s debris is concentrated in three regions: Alaska
(38.6% of total debris-covered area), Southwest Asia (12.6%) and Greenland (12.0%).
We use a set of new metrics, which include stage, the current position of a glacier
on its trajectory towards reaching its spatial carrying capacity of debris cover,
to quantify the state of glaciers. Debris cover is present on 44% of Earth’s glaciers
and prominent (>1.0 km2) on 15%. Of Earth’s glaciers, 20% have a substantial percentage
of debris cover for which the net stage is 36% and the bulk of individual glaciers
have evolved beyond an optimal moraine configuration favourable for debris-cover
expansion. Use of this dataset in global-scale models will enable improved estimates
of melt over 10.6% of the global glacier domain.'
article_processing_charge: No
article_type: original
author:
- first_name: Sam
full_name: Herreid, Sam
last_name: Herreid
- first_name: Francesca
full_name: Pellicciotti, Francesca
id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
last_name: Pellicciotti
citation:
ama: Herreid S, Pellicciotti F. The state of rock debris covering Earth’s glaciers.
Nature Geoscience. 2020;13(9):621-627. doi:10.1038/s41561-020-0615-0
apa: Herreid, S., & Pellicciotti, F. (2020). The state of rock debris covering
Earth’s glaciers. Nature Geoscience. Springer Nature. https://doi.org/10.1038/s41561-020-0615-0
chicago: Herreid, Sam, and Francesca Pellicciotti. “The State of Rock Debris Covering
Earth’s Glaciers.” Nature Geoscience. Springer Nature, 2020. https://doi.org/10.1038/s41561-020-0615-0.
ieee: S. Herreid and F. Pellicciotti, “The state of rock debris covering Earth’s
glaciers,” Nature Geoscience, vol. 13, no. 9. Springer Nature, pp. 621–627,
2020.
ista: Herreid S, Pellicciotti F. 2020. The state of rock debris covering Earth’s
glaciers. Nature Geoscience. 13(9), 621–627.
mla: Herreid, Sam, and Francesca Pellicciotti. “The State of Rock Debris Covering
Earth’s Glaciers.” Nature Geoscience, vol. 13, no. 9, Springer Nature,
2020, pp. 621–27, doi:10.1038/s41561-020-0615-0.
short: S. Herreid, F. Pellicciotti, Nature Geoscience 13 (2020) 621–627.
date_created: 2023-02-20T08:12:17Z
date_published: 2020-09-02T00:00:00Z
date_updated: 2023-02-28T12:45:37Z
day: '02'
doi: 10.1038/s41561-020-0615-0
extern: '1'
intvolume: ' 13'
issue: '9'
keyword:
- General Earth and Planetary Sciences
language:
- iso: eng
month: '09'
oa_version: None
page: 621-627
publication: Nature Geoscience
publication_identifier:
eissn:
- 1752-0908
issn:
- 1752-0894
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
link:
- relation: erratum
url: https://doi.org/10.1038/s41561-020-0630-1
scopus_import: '1'
status: public
title: The state of rock debris covering Earth’s glaciers
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 13
year: '2020'
...
---
_id: '12594'
abstract:
- lang: eng
text: Information about end-of-winter spatial distribution of snow depth is important
for seasonal forecasts of spring/summer streamflow in high-mountain regions. Nevertheless,
such information typically relies upon extrapolation from a sparse network of
observations at low elevations. Here, we test the potential of high-resolution
snow depth data derived from optical stereophotogrammetry of Pléiades satellites
for improving the representation of snow depth initial conditions (SDICs) in a
glacio-hydrological model and assess potential improvements in the skill of snowmelt
and streamflow simulations in a high-elevation Andean catchment. We calibrate
model parameters controlling glacier mass balance and snow cover evolution using
ground-based and satellite observations, and consider the relative importance
of accurate estimates of SDICs compared to model parameters and forcings. We find
that Pléiades SDICs improve the simulation of snow-covered area, glacier mass
balance, and monthly streamflow compared to alternative SDICs based upon extrapolation
of meteorological variables or statistical methods to estimate SDICs based upon
topography. Model simulations are found to be sensitive to SDICs in the early
spring (up to 48% variability in modeled streamflow compared to the best estimate
model), and to temperature gradients in all months that control albedo and melt
rates over a large elevation range (>2,400 m). As such, appropriately characterizing
the distribution of total snow volume with elevation is important for reproducing
total streamflow and the proportions of snowmelt. Therefore, optical stereo-photogrammetry
offers an advantage for obtaining SDICs that aid both the timing and magnitude
of streamflow simulations, process representation (e.g., snow cover evolution)
and has the potential for large spatial domains.
article_number: e2020WR027188
article_processing_charge: No
article_type: original
author:
- first_name: Thomas E.
full_name: Shaw, Thomas E.
last_name: Shaw
- first_name: Alexis
full_name: Caro, Alexis
last_name: Caro
- first_name: Pablo
full_name: Mendoza, Pablo
last_name: Mendoza
- first_name: Álvaro
full_name: Ayala, Álvaro
last_name: Ayala
- first_name: Francesca
full_name: Pellicciotti, Francesca
id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
last_name: Pellicciotti
- first_name: Simon
full_name: Gascoin, Simon
last_name: Gascoin
- first_name: James
full_name: McPhee, James
last_name: McPhee
citation:
ama: Shaw TE, Caro A, Mendoza P, et al. The utility of optical satellite winter
snow depths for initializing a glacio‐hydrological model of a High‐Elevation,
Andean catchment. Water Resources Research. 2020;56(8). doi:10.1029/2020wr027188
apa: Shaw, T. E., Caro, A., Mendoza, P., Ayala, Á., Pellicciotti, F., Gascoin, S.,
& McPhee, J. (2020). The utility of optical satellite winter snow depths for
initializing a glacio‐hydrological model of a High‐Elevation, Andean catchment.
Water Resources Research. American Geophysical Union. https://doi.org/10.1029/2020wr027188
chicago: Shaw, Thomas E., Alexis Caro, Pablo Mendoza, Álvaro Ayala, Francesca Pellicciotti,
Simon Gascoin, and James McPhee. “The Utility of Optical Satellite Winter Snow
Depths for Initializing a Glacio‐hydrological Model of a High‐Elevation, Andean
Catchment.” Water Resources Research. American Geophysical Union, 2020.
https://doi.org/10.1029/2020wr027188.
ieee: T. E. Shaw et al., “The utility of optical satellite winter snow depths
for initializing a glacio‐hydrological model of a High‐Elevation, Andean catchment,”
Water Resources Research, vol. 56, no. 8. American Geophysical Union, 2020.
ista: Shaw TE, Caro A, Mendoza P, Ayala Á, Pellicciotti F, Gascoin S, McPhee J.
2020. The utility of optical satellite winter snow depths for initializing a glacio‐hydrological
model of a High‐Elevation, Andean catchment. Water Resources Research. 56(8),
e2020WR027188.
mla: Shaw, Thomas E., et al. “The Utility of Optical Satellite Winter Snow Depths
for Initializing a Glacio‐hydrological Model of a High‐Elevation, Andean Catchment.”
Water Resources Research, vol. 56, no. 8, e2020WR027188, American Geophysical
Union, 2020, doi:10.1029/2020wr027188.
short: T.E. Shaw, A. Caro, P. Mendoza, Á. Ayala, F. Pellicciotti, S. Gascoin, J.
McPhee, Water Resources Research 56 (2020).
date_created: 2023-02-20T08:12:22Z
date_published: 2020-08-01T00:00:00Z
date_updated: 2023-02-28T12:41:45Z
day: '01'
doi: 10.1029/2020wr027188
extern: '1'
intvolume: ' 56'
issue: '8'
keyword:
- Water Science and Technology
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1029/2020WR027188
month: '08'
oa: 1
oa_version: Published Version
publication: Water Resources Research
publication_identifier:
eissn:
- 1944-7973
issn:
- 0043-1397
publication_status: published
publisher: American Geophysical Union
quality_controlled: '1'
scopus_import: '1'
status: public
title: The utility of optical satellite winter snow depths for initializing a glacio‐hydrological
model of a High‐Elevation, Andean catchment
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 56
year: '2020'
...
---
_id: '12595'
abstract:
- lang: eng
text: The seasonal dynamic changes of Tibetan glaciers have seen little prior investigation,
despite the increase in geodetic studies of multi-year changes. This study compares
seasonal glacier dynamics (“cold” and “warm” seasons) in the ablation zone of
Parlung No. 4 Glacier, a temperate glacier in the monsoon-influenced southeastern
Tibetan Plateau, by using repeat unpiloted aerial vehicle (UAV) surveys combined
with Structure-from-Motion (SfM) photogrammetry and ground stake measurements.
Our results showed that the surveyed ablation zone had a mean change of −2.7 m
of ice surface elevation during the period of September 2018 to October 2019 but
is characterized by significant seasonal cyclic variations with ice surface elevation
lifting (+2.0 m) in the cold season (September 2018 to June 2019) but lowering
(−4.7 m) in the warm season (June 2019 to October 2019). Over an annual timescale,
surface lowering was greatly suppressed by the resupply of ice from the glacier’s
accumulation area—the annual emergence velocity compensates for about 55% of surface
ablation in our study area. Cold season emergence velocities (3.0 ± 1.2 m) were
~5-times larger than those observed in the warm season (0.6 ± 1.0 m). Distinct
spring precipitation patterns may contribute to these distinct seasonal signals.
Such seasonal dynamic conditions are possibly critical for different glacier responses
to climate change in this region of the Tibetan Plateau, and perhaps further afield.
article_number: '2389'
article_processing_charge: No
article_type: original
author:
- first_name: Wei
full_name: Yang, Wei
last_name: Yang
- first_name: Chuanxi
full_name: Zhao, Chuanxi
last_name: Zhao
- first_name: Matthew
full_name: Westoby, Matthew
last_name: Westoby
- first_name: Tandong
full_name: Yao, Tandong
last_name: Yao
- first_name: Yongjie
full_name: Wang, Yongjie
last_name: Wang
- first_name: Francesca
full_name: Pellicciotti, Francesca
id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
last_name: Pellicciotti
- first_name: Jianmin
full_name: Zhou, Jianmin
last_name: Zhou
- first_name: Zhen
full_name: He, Zhen
last_name: He
- first_name: Evan
full_name: Miles, Evan
last_name: Miles
citation:
ama: Yang W, Zhao C, Westoby M, et al. Seasonal dynamics of a temperate Tibetan
glacier revealed by high-resolution UAV photogrammetry and in situ measurements.
Remote Sensing. 2020;12(15). doi:10.3390/rs12152389
apa: Yang, W., Zhao, C., Westoby, M., Yao, T., Wang, Y., Pellicciotti, F., … Miles,
E. (2020). Seasonal dynamics of a temperate Tibetan glacier revealed by high-resolution
UAV photogrammetry and in situ measurements. Remote Sensing. MDPI. https://doi.org/10.3390/rs12152389
chicago: Yang, Wei, Chuanxi Zhao, Matthew Westoby, Tandong Yao, Yongjie Wang, Francesca
Pellicciotti, Jianmin Zhou, Zhen He, and Evan Miles. “Seasonal Dynamics of a Temperate
Tibetan Glacier Revealed by High-Resolution UAV Photogrammetry and in Situ Measurements.”
Remote Sensing. MDPI, 2020. https://doi.org/10.3390/rs12152389.
ieee: W. Yang et al., “Seasonal dynamics of a temperate Tibetan glacier revealed
by high-resolution UAV photogrammetry and in situ measurements,” Remote Sensing,
vol. 12, no. 15. MDPI, 2020.
ista: Yang W, Zhao C, Westoby M, Yao T, Wang Y, Pellicciotti F, Zhou J, He Z, Miles
E. 2020. Seasonal dynamics of a temperate Tibetan glacier revealed by high-resolution
UAV photogrammetry and in situ measurements. Remote Sensing. 12(15), 2389.
mla: Yang, Wei, et al. “Seasonal Dynamics of a Temperate Tibetan Glacier Revealed
by High-Resolution UAV Photogrammetry and in Situ Measurements.” Remote Sensing,
vol. 12, no. 15, 2389, MDPI, 2020, doi:10.3390/rs12152389.
short: W. Yang, C. Zhao, M. Westoby, T. Yao, Y. Wang, F. Pellicciotti, J. Zhou,
Z. He, E. Miles, Remote Sensing 12 (2020).
date_created: 2023-02-20T08:12:29Z
date_published: 2020-07-24T00:00:00Z
date_updated: 2023-02-28T12:36:22Z
day: '24'
doi: 10.3390/rs12152389
extern: '1'
intvolume: ' 12'
issue: '15'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.3390/rs12152389
month: '07'
oa: 1
oa_version: Published Version
publication: Remote Sensing
publication_identifier:
issn:
- 2072-4292
publication_status: published
publisher: MDPI
quality_controlled: '1'
scopus_import: '1'
status: public
title: Seasonal dynamics of a temperate Tibetan glacier revealed by high-resolution
UAV photogrammetry and in situ measurements
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 12
year: '2020'
...
---
_id: '12596'
abstract:
- lang: eng
text: As glaciers adjust their size in response to climate variations, long-term
changes in meltwater production can be expected, affecting the local availability
of water resources. We investigate glacier runoff in the period 1955–2016 in the
Maipo River basin (4843 km2, 33.0–34.3∘ S, 69.8–70.5∘ W), in the semiarid Andes
of Chile. The basin contains more than 800 glaciers, which cover 378 km2 in total
(inventoried in 2000). We model the mass balance and runoff contribution of 26
glaciers with the physically oriented and fully distributed TOPKAPI (Topographic
Kinematic Approximation and Integration)-ETH glacio-hydrological model and extrapolate
the results to the entire basin. TOPKAPI-ETH is run at a daily time step using
several glaciological and meteorological datasets, and its results are evaluated
against streamflow records, remotely sensed snow cover, and geodetic mass balances
for the periods 1955–2000 and 2000–2013. Results show that in 1955–2016 glacier
mass balance had a general decreasing trend as a basin average but also had differences
between the main sub-catchments. Glacier volume decreased by one-fifth (from 18.6±4.5
to 14.9±2.9 km3). Runoff from the initially glacierized areas was 177±25 mm yr−1
(16±7 % of the total contributions to the basin), but it shows a decreasing sequence
of maxima, which can be linked to the interplay between a decrease in precipitation
since the 1980s and the reduction of ice melt. Glaciers in the Maipo River basin
will continue retreating because they are not in equilibrium with the current
climate. In a hypothetical constant climate scenario, glacier volume would reduce
to 81±38 % of the year 2000 volume, and glacier runoff would be 78±30 % of the
1955–2016 average. This would considerably decrease the drought mitigation capacity
of the basin.
article_processing_charge: No
article_type: original
author:
- first_name: Álvaro
full_name: Ayala, Álvaro
last_name: Ayala
- first_name: David
full_name: Farías-Barahona, David
last_name: Farías-Barahona
- first_name: Matthias
full_name: Huss, Matthias
last_name: Huss
- first_name: Francesca
full_name: Pellicciotti, Francesca
id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
last_name: Pellicciotti
- first_name: James
full_name: McPhee, James
last_name: McPhee
- first_name: Daniel
full_name: Farinotti, Daniel
last_name: Farinotti
citation:
ama: Ayala Á, Farías-Barahona D, Huss M, Pellicciotti F, McPhee J, Farinotti D.
Glacier runoff variations since 1955 in the Maipo River basin, in the semiarid
Andes of central Chile. The Cryosphere. 2020;14(6):2005-2027. doi:10.5194/tc-14-2005-2020
apa: Ayala, Á., Farías-Barahona, D., Huss, M., Pellicciotti, F., McPhee, J., &
Farinotti, D. (2020). Glacier runoff variations since 1955 in the Maipo River
basin, in the semiarid Andes of central Chile. The Cryosphere. Copernicus
Publications. https://doi.org/10.5194/tc-14-2005-2020
chicago: Ayala, Álvaro, David Farías-Barahona, Matthias Huss, Francesca Pellicciotti,
James McPhee, and Daniel Farinotti. “Glacier Runoff Variations since 1955 in the
Maipo River Basin, in the Semiarid Andes of Central Chile.” The Cryosphere.
Copernicus Publications, 2020. https://doi.org/10.5194/tc-14-2005-2020.
ieee: Á. Ayala, D. Farías-Barahona, M. Huss, F. Pellicciotti, J. McPhee, and D.
Farinotti, “Glacier runoff variations since 1955 in the Maipo River basin, in
the semiarid Andes of central Chile,” The Cryosphere, vol. 14, no. 6. Copernicus
Publications, pp. 2005–2027, 2020.
ista: Ayala Á, Farías-Barahona D, Huss M, Pellicciotti F, McPhee J, Farinotti D.
2020. Glacier runoff variations since 1955 in the Maipo River basin, in the semiarid
Andes of central Chile. The Cryosphere. 14(6), 2005–2027.
mla: Ayala, Álvaro, et al. “Glacier Runoff Variations since 1955 in the Maipo River
Basin, in the Semiarid Andes of Central Chile.” The Cryosphere, vol. 14,
no. 6, Copernicus Publications, 2020, pp. 2005–27, doi:10.5194/tc-14-2005-2020.
short: Á. Ayala, D. Farías-Barahona, M. Huss, F. Pellicciotti, J. McPhee, D. Farinotti,
The Cryosphere 14 (2020) 2005–2027.
date_created: 2023-02-20T08:12:36Z
date_published: 2020-06-24T00:00:00Z
date_updated: 2023-02-28T12:32:31Z
day: '24'
doi: 10.5194/tc-14-2005-2020
extern: '1'
intvolume: ' 14'
issue: '6'
keyword:
- Earth-Surface Processes
- Water Science and Technology
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.5194/tc-14-2005-2020
month: '06'
oa: 1
oa_version: Published Version
page: 2005-2027
publication: The Cryosphere
publication_identifier:
issn:
- 1994-0424
publication_status: published
publisher: Copernicus Publications
quality_controlled: '1'
scopus_import: '1'
status: public
title: Glacier runoff variations since 1955 in the Maipo River basin, in the semiarid
Andes of central Chile
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 14
year: '2020'
...
---
_id: '12597'
abstract:
- lang: eng
text: We examine the spatial patterns of near-surface air temperature (Ta) over
a melting glacier using a multi-annual dataset from McCall Glacier, Alaska. The
dataset consists of a 10-year (2005–2014) meteorological record along the glacier
centreline up to an upper glacier cirque, spanning an elevation difference of
900 m. We test the validity of on-glacier linear lapse rates, and a model that
calculates Ta based on the influence of katabatic winds and other heat sources
along the glacier flow line. During the coldest hours of each summer (10% of time),
average lapse rates across the entire glacier range from −4.7 to −6.7°C km−1,
with a strong relationship between Ta and elevation (R2 > 0.7). During warm conditions,
Ta shows more complex, non-linear patterns that are better explained by the flow
line-dependent model, reducing errors by up to 0.5°C compared with linear lapse
rates, although more uncertainty might be associated with these observations due
to occasionally poor sensor ventilation. We conclude that Ta spatial distribution
can vary significantly from year to year, and from one glacier section to another.
Importantly, extrapolations using linear lapse rates from the ablation zone might
lead to large underestimations of Ta on the upper glacier areas.
article_processing_charge: No
article_type: original
author:
- first_name: Patrick
full_name: Troxler, Patrick
last_name: Troxler
- first_name: Álvaro
full_name: Ayala, Álvaro
last_name: Ayala
- first_name: Thomas E.
full_name: Shaw, Thomas E.
last_name: Shaw
- first_name: Matt
full_name: Nolan, Matt
last_name: Nolan
- first_name: Ben W.
full_name: Brock, Ben W.
last_name: Brock
- first_name: Francesca
full_name: Pellicciotti, Francesca
id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
last_name: Pellicciotti
citation:
ama: Troxler P, Ayala Á, Shaw TE, Nolan M, Brock BW, Pellicciotti F. Modelling spatial
patterns of near-surface air temperature over a decade of melt seasons on McCall
Glacier, Alaska. Journal of Glaciology. 2020;66(257):386-400. doi:10.1017/jog.2020.12
apa: Troxler, P., Ayala, Á., Shaw, T. E., Nolan, M., Brock, B. W., & Pellicciotti,
F. (2020). Modelling spatial patterns of near-surface air temperature over a decade
of melt seasons on McCall Glacier, Alaska. Journal of Glaciology. Cambridge
University Press. https://doi.org/10.1017/jog.2020.12
chicago: Troxler, Patrick, Álvaro Ayala, Thomas E. Shaw, Matt Nolan, Ben W. Brock,
and Francesca Pellicciotti. “Modelling Spatial Patterns of Near-Surface Air Temperature
over a Decade of Melt Seasons on McCall Glacier, Alaska.” Journal of Glaciology.
Cambridge University Press, 2020. https://doi.org/10.1017/jog.2020.12.
ieee: P. Troxler, Á. Ayala, T. E. Shaw, M. Nolan, B. W. Brock, and F. Pellicciotti,
“Modelling spatial patterns of near-surface air temperature over a decade of melt
seasons on McCall Glacier, Alaska,” Journal of Glaciology, vol. 66, no.
257. Cambridge University Press, pp. 386–400, 2020.
ista: Troxler P, Ayala Á, Shaw TE, Nolan M, Brock BW, Pellicciotti F. 2020. Modelling
spatial patterns of near-surface air temperature over a decade of melt seasons
on McCall Glacier, Alaska. Journal of Glaciology. 66(257), 386–400.
mla: Troxler, Patrick, et al. “Modelling Spatial Patterns of Near-Surface Air Temperature
over a Decade of Melt Seasons on McCall Glacier, Alaska.” Journal of Glaciology,
vol. 66, no. 257, Cambridge University Press, 2020, pp. 386–400, doi:10.1017/jog.2020.12.
short: P. Troxler, Á. Ayala, T.E. Shaw, M. Nolan, B.W. Brock, F. Pellicciotti, Journal
of Glaciology 66 (2020) 386–400.
date_created: 2023-02-20T08:12:42Z
date_published: 2020-06-01T00:00:00Z
date_updated: 2023-02-28T12:28:45Z
day: '01'
doi: 10.1017/jog.2020.12
extern: '1'
intvolume: ' 66'
issue: '257'
keyword:
- Earth-Surface Processes
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1017/jog.2020.12
month: '06'
oa: 1
oa_version: Published Version
page: 386-400
publication: Journal of Glaciology
publication_identifier:
eissn:
- 1727-5652
issn:
- 0022-1430
publication_status: published
publisher: Cambridge University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Modelling spatial patterns of near-surface air temperature over a decade of
melt seasons on McCall Glacier, Alaska
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 66
year: '2020'
...
---
_id: '12598'
abstract:
- lang: eng
text: Obtaining detailed information about high mountain snowpacks is often limited
by insufficient ground-based observations and uncertainty in the (re)distribution
of solid precipitation. We utilize high-resolution optical images from Pléiades
satellites to generate a snow depth map, at a spatial resolution of 4 m, for a
high mountain catchment of central Chile. Results are negatively biased (median
difference of −0.22 m) when compared against observations from a terrestrial Light
Detection And Ranging scan, though replicate general snow depth variability well.
Additionally, the Pléiades dataset is subject to data gaps (17% of total pixels),
negative values for shallow snow (12%), and noise on slopes >40–50° (2%). We correct
and filter the Pléiades snow depths using surface classification techniques of
snow-free areas and a random forest model for data gap filling. Snow depths (with
an estimated error of ~0.36 m) average 1.66 m and relate well to topographical
parameters such as elevation and northness in a similar way to previous studies.
However, estimations of snow depth based upon topography (TOPO) or physically
based modeling (DBSM) cannot resolve localized processes (i.e., avalanching or
wind scouring) that are detected by Pléiades, even when forced with locally calibrated
data. Comparing these alternative model approaches to corrected Pléiades snow
depths reveals total snow volume differences between −28% (DBSM) and +54% (TOPO)
for the catchment and large differences across most elevation bands. Pléiades
represents an important contribution to understanding snow accumulation at sparsely
monitored catchments, though ideally requires a careful systematic validation
procedure to identify catchment-scale biases and errors in the snow depth derivation.
article_number: e2019WR024880
article_processing_charge: No
article_type: original
author:
- first_name: Thomas E.
full_name: Shaw, Thomas E.
last_name: Shaw
- first_name: Simon
full_name: Gascoin, Simon
last_name: Gascoin
- first_name: Pablo A.
full_name: Mendoza, Pablo A.
last_name: Mendoza
- first_name: Francesca
full_name: Pellicciotti, Francesca
id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
last_name: Pellicciotti
- first_name: James
full_name: McPhee, James
last_name: McPhee
citation:
ama: Shaw TE, Gascoin S, Mendoza PA, Pellicciotti F, McPhee J. Snow depth patterns
in a high mountain Andean catchment from satellite optical tristereoscopic remote
sensing. Water Resources Research. 2020;56(2). doi:10.1029/2019wr024880
apa: Shaw, T. E., Gascoin, S., Mendoza, P. A., Pellicciotti, F., & McPhee, J.
(2020). Snow depth patterns in a high mountain Andean catchment from satellite
optical tristereoscopic remote sensing. Water Resources Research. American
Geophysical Union. https://doi.org/10.1029/2019wr024880
chicago: Shaw, Thomas E., Simon Gascoin, Pablo A. Mendoza, Francesca Pellicciotti,
and James McPhee. “Snow Depth Patterns in a High Mountain Andean Catchment from
Satellite Optical Tristereoscopic Remote Sensing.” Water Resources Research.
American Geophysical Union, 2020. https://doi.org/10.1029/2019wr024880.
ieee: T. E. Shaw, S. Gascoin, P. A. Mendoza, F. Pellicciotti, and J. McPhee, “Snow
depth patterns in a high mountain Andean catchment from satellite optical tristereoscopic
remote sensing,” Water Resources Research, vol. 56, no. 2. American Geophysical
Union, 2020.
ista: Shaw TE, Gascoin S, Mendoza PA, Pellicciotti F, McPhee J. 2020. Snow depth
patterns in a high mountain Andean catchment from satellite optical tristereoscopic
remote sensing. Water Resources Research. 56(2), e2019WR024880.
mla: Shaw, Thomas E., et al. “Snow Depth Patterns in a High Mountain Andean Catchment
from Satellite Optical Tristereoscopic Remote Sensing.” Water Resources Research,
vol. 56, no. 2, e2019WR024880, American Geophysical Union, 2020, doi:10.1029/2019wr024880.
short: T.E. Shaw, S. Gascoin, P.A. Mendoza, F. Pellicciotti, J. McPhee, Water Resources
Research 56 (2020).
date_created: 2023-02-20T08:12:47Z
date_published: 2020-02-01T00:00:00Z
date_updated: 2023-02-28T12:26:14Z
day: '01'
doi: 10.1029/2019wr024880
extern: '1'
intvolume: ' 56'
issue: '2'
keyword:
- Water Science and Technology
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1029/2019WR024880
month: '02'
oa: 1
oa_version: Published Version
publication: Water Resources Research
publication_identifier:
eissn:
- 1944-7973
issn:
- 0043-1397
publication_status: published
publisher: American Geophysical Union
quality_controlled: '1'
scopus_import: '1'
status: public
title: Snow depth patterns in a high mountain Andean catchment from satellite optical
tristereoscopic remote sensing
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 56
year: '2020'
...
---
_id: '12599'
abstract:
- lang: eng
text: Mountains are the water towers of the world, supplying a substantial part
of both natural and anthropogenic water demands1,2. They are highly sensitive
and prone to climate change3,4, yet their importance and vulnerability have not
been quantified at the global scale. Here we present a global water tower index
(WTI), which ranks all water towers in terms of their water-supplying role and
the downstream dependence of ecosystems and society. For each water tower, we
assess its vulnerability related to water stress, governance, hydropolitical tension
and future climatic and socio-economic changes. We conclude that the most important
(highest WTI) water towers are also among the most vulnerable, and that climatic
and socio-economic changes will affect them profoundly. This could negatively
impact 1.9 billion people living in (0.3 billion) or directly downstream of (1.6
billion) mountainous areas. Immediate action is required to safeguard the future
of the world’s most important and vulnerable water towers.
article_processing_charge: No
article_type: original
author:
- first_name: W. W.
full_name: Immerzeel, W. W.
last_name: Immerzeel
- first_name: A. F.
full_name: Lutz, A. F.
last_name: Lutz
- first_name: M.
full_name: Andrade, M.
last_name: Andrade
- first_name: A.
full_name: Bahl, A.
last_name: Bahl
- first_name: H.
full_name: Biemans, H.
last_name: Biemans
- first_name: T.
full_name: Bolch, T.
last_name: Bolch
- first_name: S.
full_name: Hyde, S.
last_name: Hyde
- first_name: S.
full_name: Brumby, S.
last_name: Brumby
- first_name: B. J.
full_name: Davies, B. J.
last_name: Davies
- first_name: A. C.
full_name: Elmore, A. C.
last_name: Elmore
- first_name: A.
full_name: Emmer, A.
last_name: Emmer
- first_name: M.
full_name: Feng, M.
last_name: Feng
- first_name: A.
full_name: Fernández, A.
last_name: Fernández
- first_name: U.
full_name: Haritashya, U.
last_name: Haritashya
- first_name: J. S.
full_name: Kargel, J. S.
last_name: Kargel
- first_name: M.
full_name: Koppes, M.
last_name: Koppes
- first_name: P. D. A.
full_name: Kraaijenbrink, P. D. A.
last_name: Kraaijenbrink
- first_name: A. V.
full_name: Kulkarni, A. V.
last_name: Kulkarni
- first_name: P. A.
full_name: Mayewski, P. A.
last_name: Mayewski
- first_name: S.
full_name: Nepal, S.
last_name: Nepal
- first_name: P.
full_name: Pacheco, P.
last_name: Pacheco
- first_name: T. H.
full_name: Painter, T. H.
last_name: Painter
- first_name: Francesca
full_name: Pellicciotti, Francesca
id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70
last_name: Pellicciotti
- first_name: H.
full_name: Rajaram, H.
last_name: Rajaram
- first_name: S.
full_name: Rupper, S.
last_name: Rupper
- first_name: A.
full_name: Sinisalo, A.
last_name: Sinisalo
- first_name: A. B.
full_name: Shrestha, A. B.
last_name: Shrestha
- first_name: D.
full_name: Viviroli, D.
last_name: Viviroli
- first_name: Y.
full_name: Wada, Y.
last_name: Wada
- first_name: C.
full_name: Xiao, C.
last_name: Xiao
- first_name: T.
full_name: Yao, T.
last_name: Yao
- first_name: J. E. M.
full_name: Baillie, J. E. M.
last_name: Baillie
citation:
ama: Immerzeel WW, Lutz AF, Andrade M, et al. Importance and vulnerability of the
world’s water towers. Nature. 2020;577(7790):364-369. doi:10.1038/s41586-019-1822-y
apa: Immerzeel, W. W., Lutz, A. F., Andrade, M., Bahl, A., Biemans, H., Bolch, T.,
… Baillie, J. E. M. (2020). Importance and vulnerability of the world’s water
towers. Nature. Springer Nature. https://doi.org/10.1038/s41586-019-1822-y
chicago: Immerzeel, W. W., A. F. Lutz, M. Andrade, A. Bahl, H. Biemans, T. Bolch,
S. Hyde, et al. “Importance and Vulnerability of the World’s Water Towers.” Nature.
Springer Nature, 2020. https://doi.org/10.1038/s41586-019-1822-y.
ieee: W. W. Immerzeel et al., “Importance and vulnerability of the world’s
water towers,” Nature, vol. 577, no. 7790. Springer Nature, pp. 364–369,
2020.
ista: Immerzeel WW, Lutz AF, Andrade M, Bahl A, Biemans H, Bolch T, Hyde S, Brumby
S, Davies BJ, Elmore AC, Emmer A, Feng M, Fernández A, Haritashya U, Kargel JS,
Koppes M, Kraaijenbrink PDA, Kulkarni AV, Mayewski PA, Nepal S, Pacheco P, Painter
TH, Pellicciotti F, Rajaram H, Rupper S, Sinisalo A, Shrestha AB, Viviroli D,
Wada Y, Xiao C, Yao T, Baillie JEM. 2020. Importance and vulnerability of the
world’s water towers. Nature. 577(7790), 364–369.
mla: Immerzeel, W. W., et al. “Importance and Vulnerability of the World’s Water
Towers.” Nature, vol. 577, no. 7790, Springer Nature, 2020, pp. 364–69,
doi:10.1038/s41586-019-1822-y.
short: W.W. Immerzeel, A.F. Lutz, M. Andrade, A. Bahl, H. Biemans, T. Bolch, S.
Hyde, S. Brumby, B.J. Davies, A.C. Elmore, A. Emmer, M. Feng, A. Fernández, U.
Haritashya, J.S. Kargel, M. Koppes, P.D.A. Kraaijenbrink, A.V. Kulkarni, P.A.
Mayewski, S. Nepal, P. Pacheco, T.H. Painter, F. Pellicciotti, H. Rajaram, S.
Rupper, A. Sinisalo, A.B. Shrestha, D. Viviroli, Y. Wada, C. Xiao, T. Yao, J.E.M.
Baillie, Nature 577 (2020) 364–369.
date_created: 2023-02-20T08:12:53Z
date_published: 2020-01-16T00:00:00Z
date_updated: 2023-02-28T12:17:38Z
day: '16'
doi: 10.1038/s41586-019-1822-y
extern: '1'
intvolume: ' 577'
issue: '7790'
language:
- iso: eng
month: '01'
oa_version: None
page: 364-369
publication: Nature
publication_identifier:
eissn:
- 1476-4687
issn:
- 0028-0836
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Importance and vulnerability of the world’s water towers
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 577
year: '2020'
...
---
_id: '12939'
abstract:
- lang: eng
text: 'Linear tetrapyrroles, called phyllobilins, are obtained as major catabolites
upon chlorophyll degradation. Primarily, colorless phylloleucobilins featuring
four deconjugated pyrrole units were identified. Their yellow counterparts, phylloxanthobilins,
were discovered more recently. Although the two catabolites differ only by one
double bond, physicochemical properties are very distinct. Moreover, the presence
of the double bond seems to enhance physiologically relevant bioactivities: in
contrast to phylloleucobilin, we identified a potent anti-proliferative activity
for a phylloxanthobilin, and show that this natural product induces apoptotic
cell death and a cell cycle arrest in cancer cells. Interestingly, upon modifying
inactive phylloleucobilin by esterification, an anti-proliferative activity can
be observed that increases with the chain lengths of the alkyl esters. We provide
first evidence for anti-cancer activity of phyllobilins, report a novel plant
source for a phylloxanthobilin, and by using paper spray MS, show that these bioactive
yellow chlorophyll catabolites are more prevalent in Nature than previously assumed.'
article_processing_charge: No
article_type: original
author:
- first_name: Cornelia A.
full_name: Karg, Cornelia A.
last_name: Karg
- first_name: Pengyu
full_name: Wang, Pengyu
last_name: Wang
- first_name: Florian
full_name: Kluibenschedl, Florian
id: 7499e70e-eb2c-11ec-b98b-f925648bc9d9
last_name: Kluibenschedl
- first_name: Thomas
full_name: Müller, Thomas
last_name: Müller
- first_name: Lars
full_name: Allmendinger, Lars
last_name: Allmendinger
- first_name: Angelika M.
full_name: Vollmar, Angelika M.
last_name: Vollmar
- first_name: Simone
full_name: Moser, Simone
last_name: Moser
citation:
ama: Karg CA, Wang P, Kluibenschedl F, et al. Phylloxanthobilins are abundant linear
tetrapyrroles from chlorophyll breakdown with activities against cancer cells.
European Journal of Organic Chemistry. 2020;2020(29):4499-4509. doi:10.1002/ejoc.202000692
apa: Karg, C. A., Wang, P., Kluibenschedl, F., Müller, T., Allmendinger, L., Vollmar,
A. M., & Moser, S. (2020). Phylloxanthobilins are abundant linear tetrapyrroles
from chlorophyll breakdown with activities against cancer cells. European Journal
of Organic Chemistry. Wiley. https://doi.org/10.1002/ejoc.202000692
chicago: Karg, Cornelia A., Pengyu Wang, Florian Kluibenschedl, Thomas Müller, Lars
Allmendinger, Angelika M. Vollmar, and Simone Moser. “Phylloxanthobilins Are Abundant
Linear Tetrapyrroles from Chlorophyll Breakdown with Activities against Cancer
Cells.” European Journal of Organic Chemistry. Wiley, 2020. https://doi.org/10.1002/ejoc.202000692.
ieee: C. A. Karg et al., “Phylloxanthobilins are abundant linear tetrapyrroles
from chlorophyll breakdown with activities against cancer cells,” European
Journal of Organic Chemistry, vol. 2020, no. 29. Wiley, pp. 4499–4509, 2020.
ista: Karg CA, Wang P, Kluibenschedl F, Müller T, Allmendinger L, Vollmar AM, Moser
S. 2020. Phylloxanthobilins are abundant linear tetrapyrroles from chlorophyll
breakdown with activities against cancer cells. European Journal of Organic Chemistry.
2020(29), 4499–4509.
mla: Karg, Cornelia A., et al. “Phylloxanthobilins Are Abundant Linear Tetrapyrroles
from Chlorophyll Breakdown with Activities against Cancer Cells.” European
Journal of Organic Chemistry, vol. 2020, no. 29, Wiley, 2020, pp. 4499–509,
doi:10.1002/ejoc.202000692.
short: C.A. Karg, P. Wang, F. Kluibenschedl, T. Müller, L. Allmendinger, A.M. Vollmar,
S. Moser, European Journal of Organic Chemistry 2020 (2020) 4499–4509.
date_created: 2023-05-10T14:49:30Z
date_published: 2020-08-09T00:00:00Z
date_updated: 2023-05-15T07:57:14Z
day: '09'
doi: 10.1002/ejoc.202000692
extern: '1'
intvolume: ' 2020'
issue: '29'
keyword:
- Organic Chemistry
- Physical and Theoretical Chemistry
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1002/ejoc.202000692
month: '08'
oa: 1
oa_version: Published Version
page: 4499-4509
publication: European Journal of Organic Chemistry
publication_identifier:
issn:
- 1434-193X
- 1099-0690
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Phylloxanthobilins are abundant linear tetrapyrroles from chlorophyll breakdown
with activities against cancer cells
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2020
year: '2020'
...
---
_id: '12940'
abstract:
- lang: eng
text: Desorption electrospray ionization (DESI), easy ambient sonic-spray ionization
(EASI) and low-temperature plasma (LTP) ionization are powerful ambient ionization
techniques for mass spectrometry. However, every single method has its limitation
in terms of polarity and molecular weight of analyte molecules. After the miniaturization
of every possible component of the different ion sources, we finally were able
to embed two emitters and an ion transfer tubing into a small, hand-held device.
The pen-like interface is connected to the mass spectrometer and a separate control
unit via a bundle of flexible tubing and cables. The novel device allows the user
to ionize an extended range of chemicals by simple switching between DESI, voltage-free
EASI, or LTP ionization as well as to freely move the interface over a surface
of interest. A mini camera, which is mounted on the tip of the pen, magnifies
the desorption area and enables a simple positioning of the pen. The interface
was successfully tested using different types of chemicals, pharmaceuticals, and
real life samples. Moreover, the combination of optical data from the camera module
and chemical data obtained by mass analysis facilitates a novel type of imaging
mass spectrometry, which we name “interactive mass spectrometry imaging (IMSI)”.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Christina
full_name: Meisenbichler, Christina
last_name: Meisenbichler
- first_name: Florian
full_name: Kluibenschedl, Florian
id: 7499e70e-eb2c-11ec-b98b-f925648bc9d9
last_name: Kluibenschedl
- first_name: Thomas
full_name: Müller, Thomas
last_name: Müller
citation:
ama: Meisenbichler C, Kluibenschedl F, Müller T. A 3-in-1 hand-held ambient mass
spectrometry interface for identification and 2D localization of chemicals on
surfaces. Analytical Chemistry. 2020;92(21):14314-14318. doi:10.1021/acs.analchem.0c02615
apa: Meisenbichler, C., Kluibenschedl, F., & Müller, T. (2020). A 3-in-1 hand-held
ambient mass spectrometry interface for identification and 2D localization of
chemicals on surfaces. Analytical Chemistry. American Chemical Society.
https://doi.org/10.1021/acs.analchem.0c02615
chicago: Meisenbichler, Christina, Florian Kluibenschedl, and Thomas Müller. “A
3-in-1 Hand-Held Ambient Mass Spectrometry Interface for Identification and 2D
Localization of Chemicals on Surfaces.” Analytical Chemistry. American
Chemical Society, 2020. https://doi.org/10.1021/acs.analchem.0c02615.
ieee: C. Meisenbichler, F. Kluibenschedl, and T. Müller, “A 3-in-1 hand-held ambient
mass spectrometry interface for identification and 2D localization of chemicals
on surfaces,” Analytical Chemistry, vol. 92, no. 21. American Chemical
Society, pp. 14314–14318, 2020.
ista: Meisenbichler C, Kluibenschedl F, Müller T. 2020. A 3-in-1 hand-held ambient
mass spectrometry interface for identification and 2D localization of chemicals
on surfaces. Analytical Chemistry. 92(21), 14314–14318.
mla: Meisenbichler, Christina, et al. “A 3-in-1 Hand-Held Ambient Mass Spectrometry
Interface for Identification and 2D Localization of Chemicals on Surfaces.” Analytical
Chemistry, vol. 92, no. 21, American Chemical Society, 2020, pp. 14314–18,
doi:10.1021/acs.analchem.0c02615.
short: C. Meisenbichler, F. Kluibenschedl, T. Müller, Analytical Chemistry 92 (2020)
14314–14318.
date_created: 2023-05-10T14:50:19Z
date_published: 2020-10-16T00:00:00Z
date_updated: 2023-05-15T08:01:20Z
day: '16'
doi: 10.1021/acs.analchem.0c02615
extern: '1'
external_id:
pmid:
- '33063994'
intvolume: ' 92'
issue: '21'
keyword:
- Analytical Chemistry
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1021/acs.analchem.0c02615
month: '10'
oa: 1
oa_version: Published Version
page: 14314-14318
pmid: 1
publication: Analytical Chemistry
publication_identifier:
issn:
- 0003-2700
- 1520-6882
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: A 3-in-1 hand-held ambient mass spectrometry interface for identification and
2D localization of chemicals on surfaces
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 92
year: '2020'
...
---
_id: '9699'
abstract:
- lang: eng
text: "We investigate the structural similarities between liquid water and 53 ices,
including 20 known crystalline phases. We base such similarity comparison on the
local environments that consist of atoms within a certain cutoff radius of a central
atom. We reveal that liquid water explores the local environments of the diverse
ice phases, by directly comparing the environments in these phases using general
atomic descriptors, and also by demonstrating that a machine-learning potential
trained on liquid water alone can predict the densities, the lattice energies,
and vibrational properties of the\r\nices. The finding that the local environments
characterising the different ice phases are found in water sheds light on water
phase behaviors, and rationalizes the transferability of water models between
different phases."
article_number: '2006.13316'
article_processing_charge: No
arxiv: 1
author:
- first_name: Bartomeu
full_name: Monserrat, Bartomeu
last_name: Monserrat
- first_name: Jan Gerit
full_name: Brandenburg, Jan Gerit
last_name: Brandenburg
- first_name: Edgar A.
full_name: Engel, Edgar A.
last_name: Engel
- first_name: Bingqing
full_name: Cheng, Bingqing
id: cbe3cda4-d82c-11eb-8dc7-8ff94289fcc9
last_name: Cheng
orcid: 0000-0002-3584-9632
citation:
ama: 'Monserrat B, Brandenburg JG, Engel EA, Cheng B. Extracting ice phases from
liquid water: Why a machine-learning water model generalizes so well. arXiv.
doi:10.48550/arXiv.2006.13316'
apa: 'Monserrat, B., Brandenburg, J. G., Engel, E. A., & Cheng, B. (n.d.). Extracting
ice phases from liquid water: Why a machine-learning water model generalizes so
well. arXiv. https://doi.org/10.48550/arXiv.2006.13316'
chicago: 'Monserrat, Bartomeu, Jan Gerit Brandenburg, Edgar A. Engel, and Bingqing
Cheng. “Extracting Ice Phases from Liquid Water: Why a Machine-Learning Water
Model Generalizes so Well.” ArXiv, n.d. https://doi.org/10.48550/arXiv.2006.13316.'
ieee: 'B. Monserrat, J. G. Brandenburg, E. A. Engel, and B. Cheng, “Extracting ice
phases from liquid water: Why a machine-learning water model generalizes so well,”
arXiv. .'
ista: 'Monserrat B, Brandenburg JG, Engel EA, Cheng B. Extracting ice phases from
liquid water: Why a machine-learning water model generalizes so well. arXiv, 2006.13316.'
mla: 'Monserrat, Bartomeu, et al. “Extracting Ice Phases from Liquid Water: Why
a Machine-Learning Water Model Generalizes so Well.” ArXiv, 2006.13316,
doi:10.48550/arXiv.2006.13316.'
short: B. Monserrat, J.G. Brandenburg, E.A. Engel, B. Cheng, ArXiv (n.d.).
date_created: 2021-07-20T11:25:15Z
date_published: 2020-06-23T00:00:00Z
date_updated: 2023-05-10T10:17:48Z
day: '23'
doi: 10.48550/arXiv.2006.13316
extern: '1'
external_id:
arxiv:
- '2006.13316'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/2006.13316
month: '06'
oa: 1
oa_version: Submitted Version
publication: arXiv
publication_status: submitted
status: public
title: 'Extracting ice phases from liquid water: Why a machine-learning water model
generalizes so well'
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2020'
...
---
_id: '9706'
abstract:
- lang: eng
text: 'Additional file 2: Supplementary Tables. The association of pre-adjusted
protein levels with biological and technical covariates. Protein levels were adjusted
for age, sex, array plate and four genetic principal components (population structure)
prior to analyses. Significant associations are emboldened. (Table S1). pQTLs
associated with inflammatory biomarker levels from Bayesian penalised regression
model (Posterior Inclusion Probability > 95%). (Table S2). All pQTLs associated
with inflammatory biomarker levels from ordinary least squares regression model
(P < 7.14 × 10− 10). (Table S3). Summary of lambda values relating to ordinary
least squares GWAS and EWAS performed on inflammatory protein levels (n = 70)
in Lothian Birth Cohort 1936 study. (Table S4). Conditionally significant pQTLs
associated with inflammatory biomarker levels from ordinary least squares regression
model (P < 7.14 × 10− 10). (Table S5). Comparison of variance explained by ordinary
least squares and Bayesian penalised regression models for concordantly identified
SNPs. (Table S6). Estimate of heritability for blood protein levels as well as
proportion of variance explained attributable to different prior mixtures. (Table
S7). Comparison of heritability estimates from Ahsan et al. (maximum likelihood)
and Hillary et al. (Bayesian penalised regression). (Table S8). List of concordant
SNPs identified by linear model and Bayesian penalised regression and whether
they have been previously identified as eQTLs. (Table S9). Bayesian tests of colocalisation
for cis pQTLs and cis eQTLs. (Table S10). Sherlock algorithm: Genes whose expression
are putatively associated with circulating inflammatory proteins that harbour
pQTLs. (Table S11). CpGs associated with inflammatory protein biomarkers as identified
by Bayesian model (Bayesian model; Posterior Inclusion Probability > 95%). (Table
S12). CpGs associated with inflammatory protein biomarkers as identified by linear
model (limma) at P < 5.14 × 10− 10. (Table S13). CpGs associated with inflammatory
protein biomarkers as identified by mixed linear model (OSCA) at P < 5.14 × 10− 10.
(Table S14). Estimate of variance explained for blood protein levels by DNA methylation
as well as proportion of explained attributable to different prior mixtures -
BayesR+. (Table S15). Comparison of variance in protein levels explained by genome-wide
DNA methylation data by mixed linear model (OSCA) and Bayesian penalised regression
model (BayesR+). (Table S16). Variance in circulating inflammatory protein biomarker
levels explained by common genetic and methylation data (joint and conditional
estimates from BayesR+). Ordered by combined variance explained by genetic and
epigenetic data - smallest to largest. Significant results from t-tests comparing
distributions for variance explained by methylation or genetics alone versus combined
estimate are emboldened. (Table S17). Genetic and epigenetic factors identified
by BayesR+ when conditioning on all SNPs and CpGs together. (Table S18). Mendelian
Randomisation analyses to assess whether proteins with concordantly identified
genetic signals are causally associated with Alzheimer’s disease risk. (Table
S19).'
article_processing_charge: No
author:
- first_name: Robert F.
full_name: Hillary, Robert F.
last_name: Hillary
- first_name: Daniel
full_name: Trejo-Banos, Daniel
last_name: Trejo-Banos
- first_name: Athanasios
full_name: Kousathanas, Athanasios
last_name: Kousathanas
- first_name: Daniel L.
full_name: McCartney, Daniel L.
last_name: McCartney
- first_name: Sarah E.
full_name: Harris, Sarah E.
last_name: Harris
- first_name: Anna J.
full_name: Stevenson, Anna J.
last_name: Stevenson
- first_name: Marion
full_name: Patxot, Marion
last_name: Patxot
- first_name: Sven Erik
full_name: Ojavee, Sven Erik
last_name: Ojavee
- first_name: Qian
full_name: Zhang, Qian
last_name: Zhang
- first_name: David C.
full_name: Liewald, David C.
last_name: Liewald
- first_name: Craig W.
full_name: Ritchie, Craig W.
last_name: Ritchie
- first_name: Kathryn L.
full_name: Evans, Kathryn L.
last_name: Evans
- first_name: Elliot M.
full_name: Tucker-Drob, Elliot M.
last_name: Tucker-Drob
- first_name: Naomi R.
full_name: Wray, Naomi R.
last_name: Wray
- first_name: 'Allan F. '
full_name: 'McRae, Allan F. '
last_name: McRae
- first_name: Peter M.
full_name: Visscher, Peter M.
last_name: Visscher
- first_name: Ian J.
full_name: Deary, Ian J.
last_name: Deary
- first_name: Matthew Richard
full_name: Robinson, Matthew Richard
id: E5D42276-F5DA-11E9-8E24-6303E6697425
last_name: Robinson
orcid: 0000-0001-8982-8813
- first_name: 'Riccardo E. '
full_name: 'Marioni, Riccardo E. '
last_name: Marioni
citation:
ama: Hillary RF, Trejo-Banos D, Kousathanas A, et al. Additional file 2 of multi-method
genome- and epigenome-wide studies of inflammatory protein levels in healthy older
adults. 2020. doi:10.6084/m9.figshare.12629697.v1
apa: Hillary, R. F., Trejo-Banos, D., Kousathanas, A., McCartney, D. L., Harris,
S. E., Stevenson, A. J., … Marioni, R. E. (2020). Additional file 2 of multi-method
genome- and epigenome-wide studies of inflammatory protein levels in healthy older
adults. Springer Nature. https://doi.org/10.6084/m9.figshare.12629697.v1
chicago: Hillary, Robert F., Daniel Trejo-Banos, Athanasios Kousathanas, Daniel
L. McCartney, Sarah E. Harris, Anna J. Stevenson, Marion Patxot, et al. “Additional
File 2 of Multi-Method Genome- and Epigenome-Wide Studies of Inflammatory Protein
Levels in Healthy Older Adults.” Springer Nature, 2020. https://doi.org/10.6084/m9.figshare.12629697.v1.
ieee: R. F. Hillary et al., “Additional file 2 of multi-method genome- and
epigenome-wide studies of inflammatory protein levels in healthy older adults.”
Springer Nature, 2020.
ista: Hillary RF, Trejo-Banos D, Kousathanas A, McCartney DL, Harris SE, Stevenson
AJ, Patxot M, Ojavee SE, Zhang Q, Liewald DC, Ritchie CW, Evans KL, Tucker-Drob
EM, Wray NR, McRae AF, Visscher PM, Deary IJ, Robinson MR, Marioni RE. 2020. Additional
file 2 of multi-method genome- and epigenome-wide studies of inflammatory protein
levels in healthy older adults, Springer Nature, 10.6084/m9.figshare.12629697.v1.
mla: Hillary, Robert F., et al. Additional File 2 of Multi-Method Genome- and
Epigenome-Wide Studies of Inflammatory Protein Levels in Healthy Older Adults.
Springer Nature, 2020, doi:10.6084/m9.figshare.12629697.v1.
short: R.F. Hillary, D. Trejo-Banos, A. Kousathanas, D.L. McCartney, S.E. Harris,
A.J. Stevenson, M. Patxot, S.E. Ojavee, Q. Zhang, D.C. Liewald, C.W. Ritchie,
K.L. Evans, E.M. Tucker-Drob, N.R. Wray, A.F. McRae, P.M. Visscher, I.J. Deary,
M.R. Robinson, R.E. Marioni, (2020).
date_created: 2021-07-23T08:59:15Z
date_published: 2020-07-09T00:00:00Z
date_updated: 2023-08-22T07:55:36Z
day: '09'
department:
- _id: MaRo
doi: 10.6084/m9.figshare.12629697.v1
has_accepted_license: '1'
main_file_link:
- open_access: '1'
url: https://doi.org/10.6084/m9.figshare.12629697.v1
month: '07'
oa: 1
oa_version: Published Version
other_data_license: CC0 + CC BY (4.0)
publisher: Springer Nature
related_material:
record:
- id: '8133'
relation: used_in_publication
status: public
status: public
title: Additional file 2 of multi-method genome- and epigenome-wide studies of inflammatory
protein levels in healthy older adults
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2020'
...