---
_id: '7212'
abstract:
- lang: eng
text: The fixation probability of a single mutant invading a population of residents
is among the most widely-studied quantities in evolutionary dynamics. Amplifiers
of natural selection are population structures that increase the fixation probability
of advantageous mutants, compared to well-mixed populations. Extensive studies
have shown that many amplifiers exist for the Birth-death Moran process, some
of them substantially increasing the fixation probability or even guaranteeing
fixation in the limit of large population size. On the other hand, no amplifiers
are known for the death-Birth Moran process, and computer-assisted exhaustive
searches have failed to discover amplification. In this work we resolve this disparity,
by showing that any amplification under death-Birth updating is necessarily bounded
and transient. Our boundedness result states that even if a population structure
does amplify selection, the resulting fixation probability is close to that of
the well-mixed population. Our transience result states that for any population
structure there exists a threshold r⋆ such that the population structure ceases
to amplify selection if the mutant fitness advantage r is larger than r⋆. Finally,
we also extend the above results to δ-death-Birth updating, which is a combination
of Birth-death and death-Birth updating. On the positive side, we identify population
structures that maintain amplification for a wide range of values r and δ. These
results demonstrate that amplification of natural selection depends on the specific
mechanisms of the evolutionary process.
article_number: e1007494
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Josef
full_name: Tkadlec, Josef
id: 3F24CCC8-F248-11E8-B48F-1D18A9856A87
last_name: Tkadlec
orcid: 0000-0002-1097-9684
- first_name: Andreas
full_name: Pavlogiannis, Andreas
id: 49704004-F248-11E8-B48F-1D18A9856A87
last_name: Pavlogiannis
orcid: 0000-0002-8943-0722
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Martin A.
full_name: Nowak, Martin A.
last_name: Nowak
citation:
ama: Tkadlec J, Pavlogiannis A, Chatterjee K, Nowak MA. Limits on amplifiers of
natural selection under death-Birth updating. PLoS computational biology.
2020;16. doi:10.1371/journal.pcbi.1007494
apa: Tkadlec, J., Pavlogiannis, A., Chatterjee, K., & Nowak, M. A. (2020). Limits
on amplifiers of natural selection under death-Birth updating. PLoS Computational
Biology. Public Library of Science. https://doi.org/10.1371/journal.pcbi.1007494
chicago: Tkadlec, Josef, Andreas Pavlogiannis, Krishnendu Chatterjee, and Martin
A. Nowak. “Limits on Amplifiers of Natural Selection under Death-Birth Updating.”
PLoS Computational Biology. Public Library of Science, 2020. https://doi.org/10.1371/journal.pcbi.1007494.
ieee: J. Tkadlec, A. Pavlogiannis, K. Chatterjee, and M. A. Nowak, “Limits on amplifiers
of natural selection under death-Birth updating,” PLoS computational biology,
vol. 16. Public Library of Science, 2020.
ista: Tkadlec J, Pavlogiannis A, Chatterjee K, Nowak MA. 2020. Limits on amplifiers
of natural selection under death-Birth updating. PLoS computational biology. 16,
e1007494.
mla: Tkadlec, Josef, et al. “Limits on Amplifiers of Natural Selection under Death-Birth
Updating.” PLoS Computational Biology, vol. 16, e1007494, Public Library
of Science, 2020, doi:10.1371/journal.pcbi.1007494.
short: J. Tkadlec, A. Pavlogiannis, K. Chatterjee, M.A. Nowak, PLoS Computational
Biology 16 (2020).
date_created: 2019-12-23T13:45:11Z
date_published: 2020-01-17T00:00:00Z
date_updated: 2023-10-17T12:29:47Z
day: '17'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.1371/journal.pcbi.1007494
ec_funded: 1
external_id:
arxiv:
- '1906.02785'
isi:
- '000510916500025'
file:
- access_level: open_access
checksum: ce32ee2d2f53aed832f78bbd47e882df
content_type: application/pdf
creator: dernst
date_created: 2020-02-03T07:32:42Z
date_updated: 2020-07-14T12:47:53Z
file_id: '7441'
file_name: 2020_PlosCompBio_Tkadlec.pdf
file_size: 1817531
relation: main_file
file_date_updated: 2020-07-14T12:47:53Z
has_accepted_license: '1'
intvolume: ' 16'
isi: 1
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
project:
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11407
name: Game Theory
publication: PLoS computational biology
publication_identifier:
eissn:
- '15537358'
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
related_material:
record:
- id: '7196'
relation: part_of_dissertation
status: public
scopus_import: '1'
status: public
title: Limits on amplifiers of natural selection under death-Birth updating
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 16
year: '2020'
...
---
_id: '7213'
abstract:
- lang: eng
text: Persistent homology is a powerful tool in Topological Data Analysis (TDA)
to capture the topological properties of data succinctly at different spatial
resolutions. For graphical data, the shape, and structure of the neighborhood
of individual data items (nodes) are an essential means of characterizing their
properties. We propose the use of persistent homology methods to capture structural
and topological properties of graphs and use it to address the problem of link
prediction. We achieve encouraging results on nine different real-world datasets
that attest to the potential of persistent homology-based methods for network
analysis.
alternative_title:
- SCI
article_processing_charge: No
author:
- first_name: Sumit
full_name: Bhatia, Sumit
last_name: Bhatia
- first_name: Bapi
full_name: Chatterjee, Bapi
id: 3C41A08A-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-2742-4028
- first_name: Deepak
full_name: Nathani, Deepak
last_name: Nathani
- first_name: Manohar
full_name: Kaul, Manohar
last_name: Kaul
citation:
ama: 'Bhatia S, Chatterjee B, Nathani D, Kaul M. A persistent homology perspective
to the link prediction problem. In: Complex Networks and Their Applications
VIII. Vol 881. Springer Nature; 2020:27-39. doi:10.1007/978-3-030-36687-2_3'
apa: 'Bhatia, S., Chatterjee, B., Nathani, D., & Kaul, M. (2020). A persistent
homology perspective to the link prediction problem. In Complex Networks and
their applications VIII (Vol. 881, pp. 27–39). Lisbon, Portugal: Springer
Nature. https://doi.org/10.1007/978-3-030-36687-2_3'
chicago: Bhatia, Sumit, Bapi Chatterjee, Deepak Nathani, and Manohar Kaul. “A Persistent
Homology Perspective to the Link Prediction Problem.” In Complex Networks and
Their Applications VIII, 881:27–39. Springer Nature, 2020. https://doi.org/10.1007/978-3-030-36687-2_3.
ieee: S. Bhatia, B. Chatterjee, D. Nathani, and M. Kaul, “A persistent homology
perspective to the link prediction problem,” in Complex Networks and their
applications VIII, Lisbon, Portugal, 2020, vol. 881, pp. 27–39.
ista: 'Bhatia S, Chatterjee B, Nathani D, Kaul M. 2020. A persistent homology perspective
to the link prediction problem. Complex Networks and their applications VIII.
COMPLEX: International Conference on Complex Networks and their Applications,
SCI, vol. 881, 27–39.'
mla: Bhatia, Sumit, et al. “A Persistent Homology Perspective to the Link Prediction
Problem.” Complex Networks and Their Applications VIII, vol. 881, Springer
Nature, 2020, pp. 27–39, doi:10.1007/978-3-030-36687-2_3.
short: S. Bhatia, B. Chatterjee, D. Nathani, M. Kaul, in:, Complex Networks and
Their Applications VIII, Springer Nature, 2020, pp. 27–39.
conference:
end_date: 2019-12-12
location: Lisbon, Portugal
name: 'COMPLEX: International Conference on Complex Networks and their Applications'
start_date: 2019-12-10
date_created: 2019-12-29T23:00:45Z
date_published: 2020-01-01T00:00:00Z
date_updated: 2024-02-22T13:16:06Z
day: '01'
ddc:
- '004'
department:
- _id: DaAl
doi: 10.1007/978-3-030-36687-2_3
ec_funded: 1
external_id:
isi:
- '000843927300003'
file:
- access_level: open_access
checksum: 8951f094c8c7dae9ff8db885199bc296
content_type: application/pdf
creator: bchatter
date_created: 2020-10-08T08:16:48Z
date_updated: 2020-10-08T08:16:48Z
file_id: '8625'
file_name: main.pdf
file_size: 310598
relation: main_file
success: 1
file_date_updated: 2020-10-08T08:16:48Z
has_accepted_license: '1'
intvolume: ' 881'
isi: 1
language:
- iso: eng
month: '01'
oa: 1
oa_version: Submitted Version
page: 27-39
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: Complex Networks and their applications VIII
publication_identifier:
eissn:
- '18609503'
isbn:
- '9783030366865'
issn:
- 1860949X
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: A persistent homology perspective to the link prediction problem
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 881
year: '2020'
...
---
_id: '7218'
abstract:
- lang: eng
text: The combined resection of skull-infiltrating tumours and immediate cranioplastic
reconstruction predominantly relies on freehand-moulded solutions. Techniques
that enable this procedure to be performed easily in routine clinical practice
would be useful. A cadaveric study was developed in which a new software tool
was used to perform single-stage reconstructions with prefabricated implants after
the resection of skull-infiltrating pathologies. A novel 3D visualization and
interaction framework was developed to create 10 virtual craniotomies in five
cadaveric specimens. Polyether ether ketone (PEEK) implants were manufactured
according to the bone defects. The image-guided craniotomy was reconstructed with
PEEK and compared to polymethyl methacrylate (PMMA). Navigational accuracy and
surgical precision were assessed. The PEEK workflow resulted in up to 10-fold
shorter reconstruction times than the standard technique. Surgical precision was
reflected by the mean 1.1 ± 0.29 mm distance between the virtual and real craniotomy,
with submillimetre precision in 50%. Assessment of the global offset between virtual
and actual craniotomy revealed an average shift of 4.5 ± 3.6 mm. The results validated
the ‘elective single-stage cranioplasty’ technique as a state-of-the-art virtual
planning method and surgical workflow. This patient-tailored workflow could significantly
reduce surgical times compared to the traditional, intraoperative acrylic moulding
method and may be an option for the reconstruction of bone defects in the craniofacial
region.
article_processing_charge: No
article_type: original
author:
- first_name: Philippe
full_name: Dodier, Philippe
last_name: Dodier
- first_name: Fabian
full_name: Winter, Fabian
last_name: Winter
- first_name: Thomas
full_name: Auzinger, Thomas
id: 4718F954-F248-11E8-B48F-1D18A9856A87
last_name: Auzinger
orcid: 0000-0002-1546-3265
- first_name: Gabriel
full_name: Mistelbauer, Gabriel
last_name: Mistelbauer
- first_name: Josa M.
full_name: Frischer, Josa M.
last_name: Frischer
- first_name: Wei Te
full_name: Wang, Wei Te
last_name: Wang
- first_name: Ammar
full_name: Mallouhi, Ammar
last_name: Mallouhi
- first_name: Wolfgang
full_name: Marik, Wolfgang
last_name: Marik
- first_name: Stefan
full_name: Wolfsberger, Stefan
last_name: Wolfsberger
- first_name: Lukas
full_name: Reissig, Lukas
last_name: Reissig
- first_name: Firas
full_name: Hammadi, Firas
last_name: Hammadi
- first_name: Christian
full_name: Matula, Christian
last_name: Matula
- first_name: Arnulf
full_name: Baumann, Arnulf
last_name: Baumann
- first_name: Gerhard
full_name: Bavinzski, Gerhard
last_name: Bavinzski
citation:
ama: 'Dodier P, Winter F, Auzinger T, et al. Single-stage bone resection and cranioplastic
reconstruction: Comparison of a novel software-derived PEEK workflow with the
standard reconstructive method. International Journal of Oral and Maxillofacial
Surgery. 2020;49(8):P1007-1015. doi:10.1016/j.ijom.2019.11.011'
apa: 'Dodier, P., Winter, F., Auzinger, T., Mistelbauer, G., Frischer, J. M., Wang,
W. T., … Bavinzski, G. (2020). Single-stage bone resection and cranioplastic reconstruction:
Comparison of a novel software-derived PEEK workflow with the standard reconstructive
method. International Journal of Oral and Maxillofacial Surgery. Elsevier.
https://doi.org/10.1016/j.ijom.2019.11.011'
chicago: 'Dodier, Philippe, Fabian Winter, Thomas Auzinger, Gabriel Mistelbauer,
Josa M. Frischer, Wei Te Wang, Ammar Mallouhi, et al. “Single-Stage Bone Resection
and Cranioplastic Reconstruction: Comparison of a Novel Software-Derived PEEK
Workflow with the Standard Reconstructive Method.” International Journal of
Oral and Maxillofacial Surgery. Elsevier, 2020. https://doi.org/10.1016/j.ijom.2019.11.011.'
ieee: 'P. Dodier et al., “Single-stage bone resection and cranioplastic reconstruction:
Comparison of a novel software-derived PEEK workflow with the standard reconstructive
method,” International Journal of Oral and Maxillofacial Surgery, vol.
49, no. 8. Elsevier, pp. P1007-1015, 2020.'
ista: 'Dodier P, Winter F, Auzinger T, Mistelbauer G, Frischer JM, Wang WT, Mallouhi
A, Marik W, Wolfsberger S, Reissig L, Hammadi F, Matula C, Baumann A, Bavinzski
G. 2020. Single-stage bone resection and cranioplastic reconstruction: Comparison
of a novel software-derived PEEK workflow with the standard reconstructive method.
International Journal of Oral and Maxillofacial Surgery. 49(8), P1007-1015.'
mla: 'Dodier, Philippe, et al. “Single-Stage Bone Resection and Cranioplastic Reconstruction:
Comparison of a Novel Software-Derived PEEK Workflow with the Standard Reconstructive
Method.” International Journal of Oral and Maxillofacial Surgery, vol.
49, no. 8, Elsevier, 2020, pp. P1007-1015, doi:10.1016/j.ijom.2019.11.011.'
short: P. Dodier, F. Winter, T. Auzinger, G. Mistelbauer, J.M. Frischer, W.T. Wang,
A. Mallouhi, W. Marik, S. Wolfsberger, L. Reissig, F. Hammadi, C. Matula, A. Baumann,
G. Bavinzski, International Journal of Oral and Maxillofacial Surgery 49 (2020)
P1007-1015.
date_created: 2019-12-29T23:00:47Z
date_published: 2020-08-01T00:00:00Z
date_updated: 2023-08-17T14:15:22Z
day: '01'
department:
- _id: BeBi
doi: 10.1016/j.ijom.2019.11.011
external_id:
isi:
- '000556819800005'
pmid:
- '31866145'
intvolume: ' 49'
isi: 1
issue: '8'
language:
- iso: eng
month: '08'
oa_version: None
page: P1007-1015
pmid: 1
publication: International Journal of Oral and Maxillofacial Surgery
publication_identifier:
eissn:
- 1399-0020
issn:
- 0901-5027
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Single-stage bone resection and cranioplastic reconstruction: Comparison of
a novel software-derived PEEK workflow with the standard reconstructive method'
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 49
year: '2020'
...
---
_id: '7219'
abstract:
- lang: eng
text: Root system architecture (RSA), governed by the phytohormone auxin, endows
plants with an adaptive advantage in particular environments. Using geographically
representative arabidopsis (Arabidopsis thaliana) accessions as a resource for
GWA mapping, Waidmann et al. and Ogura et al. recently identified two novel components
involved in modulating auxin-mediated RSA and conferring plant fitness in particular
habitats.
article_processing_charge: No
article_type: original
author:
- first_name: Guanghui
full_name: Xiao, Guanghui
last_name: Xiao
- first_name: Yuzhou
full_name: Zhang, Yuzhou
id: 3B6137F2-F248-11E8-B48F-1D18A9856A87
last_name: Zhang
orcid: 0000-0003-2627-6956
citation:
ama: 'Xiao G, Zhang Y. Adaptive growth: Shaping auxin-mediated root system architecture.
Trends in Plant Science. 2020;25(2):P121-123. doi:10.1016/j.tplants.2019.12.001'
apa: 'Xiao, G., & Zhang, Y. (2020). Adaptive growth: Shaping auxin-mediated
root system architecture. Trends in Plant Science. Elsevier. https://doi.org/10.1016/j.tplants.2019.12.001'
chicago: 'Xiao, Guanghui, and Yuzhou Zhang. “Adaptive Growth: Shaping Auxin-Mediated
Root System Architecture.” Trends in Plant Science. Elsevier, 2020. https://doi.org/10.1016/j.tplants.2019.12.001.'
ieee: 'G. Xiao and Y. Zhang, “Adaptive growth: Shaping auxin-mediated root system
architecture,” Trends in Plant Science, vol. 25, no. 2. Elsevier, pp. P121-123,
2020.'
ista: 'Xiao G, Zhang Y. 2020. Adaptive growth: Shaping auxin-mediated root system
architecture. Trends in Plant Science. 25(2), P121-123.'
mla: 'Xiao, Guanghui, and Yuzhou Zhang. “Adaptive Growth: Shaping Auxin-Mediated
Root System Architecture.” Trends in Plant Science, vol. 25, no. 2, Elsevier,
2020, pp. P121-123, doi:10.1016/j.tplants.2019.12.001.'
short: G. Xiao, Y. Zhang, Trends in Plant Science 25 (2020) P121-123.
date_created: 2019-12-29T23:00:48Z
date_published: 2020-02-01T00:00:00Z
date_updated: 2023-08-17T14:14:50Z
day: '01'
department:
- _id: JiFr
doi: 10.1016/j.tplants.2019.12.001
external_id:
isi:
- '000508637500001'
pmid:
- '31843370'
intvolume: ' 25'
isi: 1
issue: '2'
language:
- iso: eng
month: '02'
oa_version: None
page: P121-123
pmid: 1
publication: Trends in Plant Science
publication_identifier:
issn:
- '13601385'
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Adaptive growth: Shaping auxin-mediated root system architecture'
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 25
year: '2020'
...
---
_id: '7220'
abstract:
- lang: eng
text: BACKGROUND:The introduction of image-guided methods to bypass surgery has
resulted in optimized preoperative identification of the recipients and excellent
patency rates. However, the recently presented methods have also been resource-consuming.
In the present study, we have reported a cost-efficient planning workflow for
extracranial-intracranial (EC-IC) revascularization combined with transdural indocyanine
green videoangiography (tICG-VA). METHODS:We performed a retrospective review
at a single tertiary referral center from 2011 to 2018. A novel software-derived
workflow was applied for 25 of 92 bypass procedures during the study period. The
precision and accuracy were assessed using tICG-VA identification of the cortical
recipients and a comparison of the virtual and actual data. The data from a control
group of 25 traditionally planned procedures were also matched. RESULTS:The intraoperative
transfer time of the calculated coordinates averaged 0.8 minute (range, 0.4-1.9
minutes). The definitive recipients matched the targeted branches in 80%, and
a neighboring branch was used in 16%. Our workflow led to a significant craniotomy
size reduction in the study group compared with that in the control group (P =
0.005). tICG-VA was successfully applied in 19 cases. An average of 2 potential
recipient arteries were identified transdurally, resulting in tailored durotomy
and 3 craniotomy adjustments. Follow-up patency results were available for 49
bypass surgeries, comprising 54 grafts. The overall patency rate was 91% at a
median follow-up period of 26 months. No significant difference was found in the
patency rate between the study and control groups (P = 0.317). CONCLUSIONS:Our
clinical results have validated the presented planning and surgical workflow and
support the routine implementation of tICG-VA for recipient identification before
durotomy.
article_processing_charge: No
article_type: original
author:
- first_name: Philippe
full_name: Dodier, Philippe
last_name: Dodier
- first_name: Thomas
full_name: Auzinger, Thomas
id: 4718F954-F248-11E8-B48F-1D18A9856A87
last_name: Auzinger
orcid: 0000-0002-1546-3265
- first_name: Gabriel
full_name: Mistelbauer, Gabriel
last_name: Mistelbauer
- first_name: Wei Te
full_name: Wang, Wei Te
last_name: Wang
- first_name: Heber
full_name: Ferraz-Leite, Heber
last_name: Ferraz-Leite
- first_name: Andreas
full_name: Gruber, Andreas
last_name: Gruber
- first_name: Wolfgang
full_name: Marik, Wolfgang
last_name: Marik
- first_name: Fabian
full_name: Winter, Fabian
last_name: Winter
- first_name: Gerrit
full_name: Fischer, Gerrit
last_name: Fischer
- first_name: Josa M.
full_name: Frischer, Josa M.
last_name: Frischer
- first_name: Gerhard
full_name: Bavinzski, Gerhard
last_name: Bavinzski
citation:
ama: Dodier P, Auzinger T, Mistelbauer G, et al. Novel software-derived workflow
in extracranial–intracranial bypass surgery validated by transdural indocyanine
green videoangiography. World Neurosurgery. 2020;134(2):e892-e902. doi:10.1016/j.wneu.2019.11.038
apa: Dodier, P., Auzinger, T., Mistelbauer, G., Wang, W. T., Ferraz-Leite, H., Gruber,
A., … Bavinzski, G. (2020). Novel software-derived workflow in extracranial–intracranial
bypass surgery validated by transdural indocyanine green videoangiography. World
Neurosurgery. Elsevier. https://doi.org/10.1016/j.wneu.2019.11.038
chicago: Dodier, Philippe, Thomas Auzinger, Gabriel Mistelbauer, Wei Te Wang, Heber
Ferraz-Leite, Andreas Gruber, Wolfgang Marik, et al. “Novel Software-Derived Workflow
in Extracranial–Intracranial Bypass Surgery Validated by Transdural Indocyanine
Green Videoangiography.” World Neurosurgery. Elsevier, 2020. https://doi.org/10.1016/j.wneu.2019.11.038.
ieee: P. Dodier et al., “Novel software-derived workflow in extracranial–intracranial
bypass surgery validated by transdural indocyanine green videoangiography,” World
Neurosurgery, vol. 134, no. 2. Elsevier, pp. e892–e902, 2020.
ista: Dodier P, Auzinger T, Mistelbauer G, Wang WT, Ferraz-Leite H, Gruber A, Marik
W, Winter F, Fischer G, Frischer JM, Bavinzski G. 2020. Novel software-derived
workflow in extracranial–intracranial bypass surgery validated by transdural indocyanine
green videoangiography. World Neurosurgery. 134(2), e892–e902.
mla: Dodier, Philippe, et al. “Novel Software-Derived Workflow in Extracranial–Intracranial
Bypass Surgery Validated by Transdural Indocyanine Green Videoangiography.” World
Neurosurgery, vol. 134, no. 2, Elsevier, 2020, pp. e892–902, doi:10.1016/j.wneu.2019.11.038.
short: P. Dodier, T. Auzinger, G. Mistelbauer, W.T. Wang, H. Ferraz-Leite, A. Gruber,
W. Marik, F. Winter, G. Fischer, J.M. Frischer, G. Bavinzski, World Neurosurgery
134 (2020) e892–e902.
date_created: 2019-12-29T23:00:48Z
date_published: 2020-02-01T00:00:00Z
date_updated: 2023-08-17T14:14:23Z
day: '01'
department:
- _id: BeBi
doi: 10.1016/j.wneu.2019.11.038
external_id:
isi:
- '000512878200104'
pmid:
- '31733380'
intvolume: ' 134'
isi: 1
issue: '2'
language:
- iso: eng
month: '02'
oa_version: None
page: e892-e902
pmid: 1
publication: World Neurosurgery
publication_identifier:
eissn:
- 1878-8769
issn:
- 1878-8750
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Novel software-derived workflow in extracranial–intracranial bypass surgery
validated by transdural indocyanine green videoangiography
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 134
year: '2020'
...
---
_id: '7224'
abstract:
- lang: eng
text: 'Habitat loss is one of the key drivers of the ongoing decline of biodiversity.
However, ecologists still argue about how fragmentation of habitat (independent
of habitat loss) affects species richness. The recently proposed habitat amount
hypothesis posits that species richness only depends on the total amount of habitat
in a local landscape. In contrast, empirical studies report contrasting patterns:
some find positive and others negative effects of fragmentation per se on species
richness. To explain this apparent disparity, we devise a stochastic, spatially
explicit model of competitive species communities in heterogeneous habitats. The
model shows that habitat loss and fragmentation have complex effects on species
diversity in competitive communities. When the total amount of habitat is large,
fragmentation per se tends to increase species diversity, but if the total amount
of habitat is small, the situation is reversed: fragmentation per se decreases
species diversity.'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Joel
full_name: Rybicki, Joel
id: 334EFD2E-F248-11E8-B48F-1D18A9856A87
last_name: Rybicki
orcid: 0000-0002-6432-6646
- first_name: Nerea
full_name: Abrego, Nerea
last_name: Abrego
- first_name: Otso
full_name: Ovaskainen, Otso
last_name: Ovaskainen
citation:
ama: Rybicki J, Abrego N, Ovaskainen O. Habitat fragmentation and species diversity
in competitive communities. Ecology Letters. 2020;23(3):506-517. doi:10.1111/ele.13450
apa: Rybicki, J., Abrego, N., & Ovaskainen, O. (2020). Habitat fragmentation
and species diversity in competitive communities. Ecology Letters. Wiley.
https://doi.org/10.1111/ele.13450
chicago: Rybicki, Joel, Nerea Abrego, and Otso Ovaskainen. “Habitat Fragmentation
and Species Diversity in Competitive Communities.” Ecology Letters. Wiley,
2020. https://doi.org/10.1111/ele.13450.
ieee: J. Rybicki, N. Abrego, and O. Ovaskainen, “Habitat fragmentation and species
diversity in competitive communities,” Ecology Letters, vol. 23, no. 3.
Wiley, pp. 506–517, 2020.
ista: Rybicki J, Abrego N, Ovaskainen O. 2020. Habitat fragmentation and species
diversity in competitive communities. Ecology Letters. 23(3), 506–517.
mla: Rybicki, Joel, et al. “Habitat Fragmentation and Species Diversity in Competitive
Communities.” Ecology Letters, vol. 23, no. 3, Wiley, 2020, pp. 506–17,
doi:10.1111/ele.13450.
short: J. Rybicki, N. Abrego, O. Ovaskainen, Ecology Letters 23 (2020) 506–517.
date_created: 2020-01-04T11:04:30Z
date_published: 2020-03-01T00:00:00Z
date_updated: 2023-09-05T16:04:30Z
day: '01'
ddc:
- '000'
department:
- _id: DaAl
doi: 10.1111/ele.13450
ec_funded: 1
external_id:
isi:
- '000503625200001'
file:
- access_level: open_access
checksum: 372f67f2744f4b6049e9778364766c22
content_type: application/pdf
creator: dernst
date_created: 2020-02-14T12:02:50Z
date_updated: 2020-07-14T12:47:54Z
file_id: '7486'
file_name: 2020_EcologyLetters_Rybicki.pdf
file_size: 3005474
relation: main_file
file_date_updated: 2020-07-14T12:47:54Z
has_accepted_license: '1'
intvolume: ' 23'
isi: 1
issue: '3'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 506-517
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
- _id: 26A5D39A-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '840605'
name: Coordination in constrained and natural distributed systems
publication: Ecology Letters
publication_identifier:
eissn:
- 1461-0248
issn:
- 1461-023X
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Habitat fragmentation and species diversity in competitive communities
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 23
year: '2020'
...
---
_id: '7227'
abstract:
- lang: eng
text: Gastrulation entails specification and formation of three embryonic germ layers—ectoderm,
mesoderm and endoderm—thereby establishing the basis for the future body plan.
In zebrafish embryos, germ layer specification occurs during blastula and early
gastrula stages (Ho & Kimmel, 1993), a period when the main morphogenetic movements
underlying gastrulation are initiated. Hence, the signals driving progenitor cell
fate specification, such as Nodal ligands from the TGF-β family, also play key
roles in regulating germ layer progenitor cell segregation (Carmany-Rampey & Schier,
2001; David & Rosa, 2001; Feldman et al., 2000; Gritsman et al., 1999; Keller
et al., 2008). In this review, we summarize and discuss the main signaling pathways
involved in germ layer progenitor cell fate specification and segregation, specifically
focusing on recent advances in understanding the interplay between mesoderm and
endoderm specification and the internalization movements at the onset of zebrafish
gastrulation.
acknowledgement: We thank Alexandra Schauer, Nicoletta Petridou and Feyza Nur Arslan
for comments on the manuscript. Research in the Heisenberg laboratory is supported
by an ERC Advanced Grant (MECSPEC 742573), ANR/FWF (I03601) and FWF/DFG (I03196)
International Cooperation Grants. D. Pinheiro acknowledges a fellowship from EMBO
ALTF (850-2017) and is currently supported by HFSP LTF (LT000429/2018-L2).
alternative_title:
- Current Topics in Developmental Biology
article_processing_charge: No
author:
- first_name: Diana C
full_name: Nunes Pinheiro, Diana C
id: 2E839F16-F248-11E8-B48F-1D18A9856A87
last_name: Nunes Pinheiro
orcid: 0000-0003-4333-7503
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: 'Nunes Pinheiro DC, Heisenberg C-PJ. Zebrafish gastrulation: Putting fate in
motion. In: Gastrulation: From Embryonic Pattern to Form. Vol 136. Elsevier;
2020:343-375. doi:10.1016/bs.ctdb.2019.10.009'
apa: 'Nunes Pinheiro, D. C., & Heisenberg, C.-P. J. (2020). Zebrafish gastrulation:
Putting fate in motion. In Gastrulation: From Embryonic Pattern to Form
(Vol. 136, pp. 343–375). Elsevier. https://doi.org/10.1016/bs.ctdb.2019.10.009'
chicago: 'Nunes Pinheiro, Diana C, and Carl-Philipp J Heisenberg. “Zebrafish Gastrulation:
Putting Fate in Motion.” In Gastrulation: From Embryonic Pattern to Form,
136:343–75. Elsevier, 2020. https://doi.org/10.1016/bs.ctdb.2019.10.009.'
ieee: 'D. C. Nunes Pinheiro and C.-P. J. Heisenberg, “Zebrafish gastrulation: Putting
fate in motion,” in Gastrulation: From Embryonic Pattern to Form, vol.
136, Elsevier, 2020, pp. 343–375.'
ista: 'Nunes Pinheiro DC, Heisenberg C-PJ. 2020.Zebrafish gastrulation: Putting
fate in motion. In: Gastrulation: From Embryonic Pattern to Form. Current Topics
in Developmental Biology, vol. 136, 343–375.'
mla: 'Nunes Pinheiro, Diana C., and Carl-Philipp J. Heisenberg. “Zebrafish Gastrulation:
Putting Fate in Motion.” Gastrulation: From Embryonic Pattern to Form,
vol. 136, Elsevier, 2020, pp. 343–75, doi:10.1016/bs.ctdb.2019.10.009.'
short: 'D.C. Nunes Pinheiro, C.-P.J. Heisenberg, in:, Gastrulation: From Embryonic
Pattern to Form, Elsevier, 2020, pp. 343–375.'
date_created: 2020-01-05T23:00:46Z
date_published: 2020-06-01T00:00:00Z
date_updated: 2023-09-06T14:54:36Z
day: '01'
department:
- _id: CaHe
doi: 10.1016/bs.ctdb.2019.10.009
ec_funded: 1
external_id:
isi:
- '000611830600013'
pmid:
- '31959295'
intvolume: ' 136'
isi: 1
language:
- iso: eng
month: '06'
oa_version: None
page: 343-375
pmid: 1
project:
- _id: 260F1432-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '742573'
name: Interaction and feedback between cell mechanics and fate specification in
vertebrate gastrulation
- _id: 2646861A-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: I03601
name: Control of embryonic cleavage pattern
- _id: 2608FC64-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: I03196
name: Control of epithelial cell layer spreading in zebrafish
- _id: 266BC5CE-B435-11E9-9278-68D0E5697425
grant_number: LT000429
name: Coordination of mesendoderm fate specification and internalization during
zebrafish gastrulation
- _id: 26520D1E-B435-11E9-9278-68D0E5697425
grant_number: ALTF 850-2017
name: Coordination of mesendoderm cell fate specification and internalization during
zebrafish gastrulation
publication: 'Gastrulation: From Embryonic Pattern to Form'
publication_identifier:
issn:
- '00702153'
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Zebrafish gastrulation: Putting fate in motion'
type: book_chapter
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 136
year: '2020'
...
---
_id: '7234'
abstract:
- lang: eng
text: T lymphocytes utilize amoeboid migration to navigate effectively within complex
microenvironments. The precise rearrangement of the actin cytoskeleton required
for cellular forward propulsion is mediated by actin regulators, including the
actin‐related protein 2/3 (Arp2/3) complex, a macromolecular machine that nucleates
branched actin filaments at the leading edge. The consequences of modulating Arp2/3
activity on the biophysical properties of the actomyosin cortex and downstream
T cell function are incompletely understood. We report that even a moderate decrease
of Arp3 levels in T cells profoundly affects actin cortex integrity. Reduction
in total F‐actin content leads to reduced cortical tension and disrupted lamellipodia
formation. Instead, in Arp3‐knockdown cells, the motility mode is dominated by
blebbing migration characterized by transient, balloon‐like protrusions at the
leading edge. Although this migration mode seems to be compatible with interstitial
migration in three‐dimensional environments, diminished locomotion kinetics and
impaired cytotoxicity interfere with optimal T cell function. These findings define
the importance of finely tuned, Arp2/3‐dependent mechanophysical membrane integrity
in cytotoxic effector T lymphocyte activities.
article_processing_charge: No
article_type: original
author:
- first_name: Peyman
full_name: Obeidy, Peyman
last_name: Obeidy
- first_name: Lining A.
full_name: Ju, Lining A.
last_name: Ju
- first_name: Stefan H.
full_name: Oehlers, Stefan H.
last_name: Oehlers
- first_name: Nursafwana S.
full_name: Zulkhernain, Nursafwana S.
last_name: Zulkhernain
- first_name: Quintin
full_name: Lee, Quintin
last_name: Lee
- first_name: Jorge L.
full_name: Galeano Niño, Jorge L.
last_name: Galeano Niño
- first_name: Rain Y.Q.
full_name: Kwan, Rain Y.Q.
last_name: Kwan
- first_name: Shweta
full_name: Tikoo, Shweta
last_name: Tikoo
- first_name: Lois L.
full_name: Cavanagh, Lois L.
last_name: Cavanagh
- first_name: Paulus
full_name: Mrass, Paulus
last_name: Mrass
- first_name: Adam J.L.
full_name: Cook, Adam J.L.
last_name: Cook
- first_name: Shaun P.
full_name: Jackson, Shaun P.
last_name: Jackson
- first_name: Maté
full_name: Biro, Maté
last_name: Biro
- first_name: Ben
full_name: Roediger, Ben
last_name: Roediger
- first_name: Michael K
full_name: Sixt, Michael K
id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
last_name: Sixt
orcid: 0000-0002-6620-9179
- first_name: Wolfgang
full_name: Weninger, Wolfgang
last_name: Weninger
citation:
ama: Obeidy P, Ju LA, Oehlers SH, et al. Partial loss of actin nucleator actin-related
protein 2/3 activity triggers blebbing in primary T lymphocytes. Immunology
and Cell Biology. 2020;98(2):93-113. doi:10.1111/imcb.12304
apa: Obeidy, P., Ju, L. A., Oehlers, S. H., Zulkhernain, N. S., Lee, Q., Galeano
Niño, J. L., … Weninger, W. (2020). Partial loss of actin nucleator actin-related
protein 2/3 activity triggers blebbing in primary T lymphocytes. Immunology
and Cell Biology. Wiley. https://doi.org/10.1111/imcb.12304
chicago: Obeidy, Peyman, Lining A. Ju, Stefan H. Oehlers, Nursafwana S. Zulkhernain,
Quintin Lee, Jorge L. Galeano Niño, Rain Y.Q. Kwan, et al. “Partial Loss of Actin
Nucleator Actin-Related Protein 2/3 Activity Triggers Blebbing in Primary T Lymphocytes.”
Immunology and Cell Biology. Wiley, 2020. https://doi.org/10.1111/imcb.12304.
ieee: P. Obeidy et al., “Partial loss of actin nucleator actin-related protein
2/3 activity triggers blebbing in primary T lymphocytes,” Immunology and Cell
Biology, vol. 98, no. 2. Wiley, pp. 93–113, 2020.
ista: Obeidy P, Ju LA, Oehlers SH, Zulkhernain NS, Lee Q, Galeano Niño JL, Kwan
RYQ, Tikoo S, Cavanagh LL, Mrass P, Cook AJL, Jackson SP, Biro M, Roediger B,
Sixt MK, Weninger W. 2020. Partial loss of actin nucleator actin-related protein
2/3 activity triggers blebbing in primary T lymphocytes. Immunology and Cell Biology.
98(2), 93–113.
mla: Obeidy, Peyman, et al. “Partial Loss of Actin Nucleator Actin-Related Protein
2/3 Activity Triggers Blebbing in Primary T Lymphocytes.” Immunology and Cell
Biology, vol. 98, no. 2, Wiley, 2020, pp. 93–113, doi:10.1111/imcb.12304.
short: P. Obeidy, L.A. Ju, S.H. Oehlers, N.S. Zulkhernain, Q. Lee, J.L. Galeano
Niño, R.Y.Q. Kwan, S. Tikoo, L.L. Cavanagh, P. Mrass, A.J.L. Cook, S.P. Jackson,
M. Biro, B. Roediger, M.K. Sixt, W. Weninger, Immunology and Cell Biology 98 (2020)
93–113.
date_created: 2020-01-05T23:00:48Z
date_published: 2020-02-01T00:00:00Z
date_updated: 2023-08-17T14:21:12Z
day: '01'
ddc:
- '570'
department:
- _id: MiSi
doi: 10.1111/imcb.12304
external_id:
isi:
- '000503885600001'
pmid:
- '31698518'
file:
- access_level: open_access
checksum: c389477b4b52172ef76afff8a06c6775
content_type: application/pdf
creator: dernst
date_created: 2020-11-19T11:22:33Z
date_updated: 2020-11-19T11:22:33Z
file_id: '8775'
file_name: 2020_ImmunologyCellBio_Obeidy.pdf
file_size: 8569945
relation: main_file
success: 1
file_date_updated: 2020-11-19T11:22:33Z
has_accepted_license: '1'
intvolume: ' 98'
isi: 1
issue: '2'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
page: 93-113
pmid: 1
publication: Immunology and Cell Biology
publication_identifier:
eissn:
- '14401711'
issn:
- '08189641'
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Partial loss of actin nucleator actin-related protein 2/3 activity triggers
blebbing in primary T lymphocytes
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 98
year: '2020'
...
---
_id: '7235'
abstract:
- lang: eng
text: We consider the Fröhlich model of a polaron, and show that its effective mass
diverges in thestrong coupling limit.
acknowledgement: Open access funding provided by Institute of Science and Technology
(IST Austria). Financial support through the European Research Council (ERC) under
the European Union’s Horizon 2020 research and innovation programme (Grant Agreement
No. 694227; R.S.) is gratefully acknowledged.
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Elliott H.
full_name: Lieb, Elliott H.
last_name: Lieb
- first_name: Robert
full_name: Seiringer, Robert
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
citation:
ama: Lieb EH, Seiringer R. Divergence of the effective mass of a polaron in the
strong coupling limit. Journal of Statistical Physics. 2020;180:23-33.
doi:10.1007/s10955-019-02322-3
apa: Lieb, E. H., & Seiringer, R. (2020). Divergence of the effective mass of
a polaron in the strong coupling limit. Journal of Statistical Physics.
Springer Nature. https://doi.org/10.1007/s10955-019-02322-3
chicago: Lieb, Elliott H., and Robert Seiringer. “Divergence of the Effective Mass
of a Polaron in the Strong Coupling Limit.” Journal of Statistical Physics.
Springer Nature, 2020. https://doi.org/10.1007/s10955-019-02322-3.
ieee: E. H. Lieb and R. Seiringer, “Divergence of the effective mass of a polaron
in the strong coupling limit,” Journal of Statistical Physics, vol. 180.
Springer Nature, pp. 23–33, 2020.
ista: Lieb EH, Seiringer R. 2020. Divergence of the effective mass of a polaron
in the strong coupling limit. Journal of Statistical Physics. 180, 23–33.
mla: Lieb, Elliott H., and Robert Seiringer. “Divergence of the Effective Mass of
a Polaron in the Strong Coupling Limit.” Journal of Statistical Physics,
vol. 180, Springer Nature, 2020, pp. 23–33, doi:10.1007/s10955-019-02322-3.
short: E.H. Lieb, R. Seiringer, Journal of Statistical Physics 180 (2020) 23–33.
date_created: 2020-01-07T09:42:03Z
date_published: 2020-09-01T00:00:00Z
date_updated: 2023-09-05T14:57:29Z
day: '01'
ddc:
- '510'
- '530'
department:
- _id: RoSe
doi: 10.1007/s10955-019-02322-3
ec_funded: 1
external_id:
isi:
- '000556199700003'
file:
- access_level: open_access
checksum: 1e67bee6728592f7bdcea2ad2d9366dc
content_type: application/pdf
creator: dernst
date_created: 2020-11-19T11:13:55Z
date_updated: 2020-11-19T11:13:55Z
file_id: '8774'
file_name: 2020_JourStatPhysics_Lieb.pdf
file_size: 279749
relation: main_file
success: 1
file_date_updated: 2020-11-19T11:13:55Z
has_accepted_license: '1'
intvolume: ' 180'
isi: 1
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: 23-33
project:
- _id: B67AFEDC-15C9-11EA-A837-991A96BB2854
name: IST Austria Open Access Fund
- _id: 25C6DC12-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '694227'
name: Analysis of quantum many-body systems
publication: Journal of Statistical Physics
publication_identifier:
eissn:
- 1572-9613
issn:
- 0022-4715
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Divergence of the effective mass of a polaron in the strong coupling limit
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 180
year: '2020'
...
---
_id: '7236'
abstract:
- lang: eng
text: The biotic interactions hypothesis posits that biotic interactions are more
important drivers of adaptation closer to the equator, evidenced by “stronger”
contemporary interactions (e.g. greater interaction rates) and/or patterns of
trait evolution consistent with a history of stronger interactions. Support for
the hypothesis is mixed, but few studies span tropical and temperate regions while
experimentally controlling for evolutionary history. Here, we integrate field
observations and common garden experiments to quantify the relative importance
of pollination and herbivory in a pair of tropical‐temperate congeneric perennial
herbs. Phytolacca rivinoides and P. americana are pioneer species native to the
Neotropics and the eastern USA, respectively. We compared plant‐pollinator and
plant‐herbivore interactions between three tropical populations of P. rivinoides
from Costa Rica and three temperate populations of P. americana from its northern
range edge in Michigan and Ohio. For some metrics of interaction importance, we
also included three subtropical populations of P. americana from its southern
range edge in Florida. This approach confounds species and region but allows us,
uniquely, to measure complementary proxies of interaction importance across a
tropical‐temperate range in one system. To test the prediction that lower‐latitude
plants are more reliant on insect pollinators, we quantified floral display and
reward, insect visitation rates, and self‐pollination ability (autogamy). To test
the prediction that lower‐latitude plants experience more herbivore pressure,
we quantified herbivory rates, herbivore abundance, and leaf palatability. We
found evidence supporting the biotic interactions hypothesis for most comparisons
between P. rivinoides and north‐temperate P. americana (floral display, insect
visitation, autogamy, herbivory, herbivore abundance, and young‐leaf palatability).
Results for subtropical P. americana populations, however, were typically not
intermediate between P. rivinoides and north‐temperate P. americana, as would
be predicted by a linear latitudinal gradient in interaction importance. Subtropical
young‐leaf palatability was intermediate, but subtropical mature leaves were the
least palatable, and pollination‐related traits did not differ between temperate
and subtropical regions. These nonlinear patterns of interaction importance suggest
future work to relate interaction importance to climatic or biotic thresholds.
In sum, we found that the biotic interactions hypothesis was more consistently
supported at the larger spatial scale of our study.
article_number: e01397
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Carina
full_name: Baskett, Carina
id: 3B4A7CE2-F248-11E8-B48F-1D18A9856A87
last_name: Baskett
orcid: 0000-0002-7354-8574
- first_name: Lucy
full_name: Schroeder, Lucy
last_name: Schroeder
- first_name: Marjorie G.
full_name: Weber, Marjorie G.
last_name: Weber
- first_name: Douglas W.
full_name: Schemske, Douglas W.
last_name: Schemske
citation:
ama: Baskett C, Schroeder L, Weber MG, Schemske DW. Multiple metrics of latitudinal
patterns in insect pollination and herbivory for a tropical‐temperate congener
pair. Ecological Monographs. 2020;90(1). doi:10.1002/ecm.1397
apa: Baskett, C., Schroeder, L., Weber, M. G., & Schemske, D. W. (2020). Multiple
metrics of latitudinal patterns in insect pollination and herbivory for a tropical‐temperate
congener pair. Ecological Monographs. Wiley. https://doi.org/10.1002/ecm.1397
chicago: Baskett, Carina, Lucy Schroeder, Marjorie G. Weber, and Douglas W. Schemske.
“Multiple Metrics of Latitudinal Patterns in Insect Pollination and Herbivory
for a Tropical‐temperate Congener Pair.” Ecological Monographs. Wiley,
2020. https://doi.org/10.1002/ecm.1397.
ieee: C. Baskett, L. Schroeder, M. G. Weber, and D. W. Schemske, “Multiple metrics
of latitudinal patterns in insect pollination and herbivory for a tropical‐temperate
congener pair,” Ecological Monographs, vol. 90, no. 1. Wiley, 2020.
ista: Baskett C, Schroeder L, Weber MG, Schemske DW. 2020. Multiple metrics of latitudinal
patterns in insect pollination and herbivory for a tropical‐temperate congener
pair. Ecological Monographs. 90(1), e01397.
mla: Baskett, Carina, et al. “Multiple Metrics of Latitudinal Patterns in Insect
Pollination and Herbivory for a Tropical‐temperate Congener Pair.” Ecological
Monographs, vol. 90, no. 1, e01397, Wiley, 2020, doi:10.1002/ecm.1397.
short: C. Baskett, L. Schroeder, M.G. Weber, D.W. Schemske, Ecological Monographs
90 (2020).
date_created: 2020-01-07T12:47:07Z
date_published: 2020-02-01T00:00:00Z
date_updated: 2023-09-05T15:43:19Z
day: '01'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1002/ecm.1397
ec_funded: 1
external_id:
isi:
- '000508511600001'
file:
- access_level: open_access
checksum: ab8130c6e68101f5a091d05324c36f08
content_type: application/pdf
creator: dernst
date_created: 2020-02-10T08:18:14Z
date_updated: 2020-07-14T12:47:54Z
file_id: '7469'
file_name: 2020_EcologMono_Baskett.pdf
file_size: 537941
relation: main_file
file_date_updated: 2020-07-14T12:47:54Z
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intvolume: ' 90'
isi: 1
issue: '1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc/4.0/
month: '02'
oa: 1
oa_version: Published Version
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: Ecological Monographs
publication_identifier:
eissn:
- 1557-7015
issn:
- 0012-9615
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Multiple metrics of latitudinal patterns in insect pollination and herbivory
for a tropical‐temperate congener pair
tmp:
image: /images/cc_by_nc.png
legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
short: CC BY-NC (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 90
year: '2020'
...
---
_id: '7253'
abstract:
- lang: eng
text: The cyclin-dependent kinase inhibitor p57KIP2 is encoded by the imprinted
Cdkn1c locus, exhibits maternal expression, and is essential for cerebral cortex
development. How Cdkn1c regulates corticogenesis is however not clear. To this
end we employ Mosaic Analysis with Double Markers (MADM) technology to genetically
dissect Cdkn1c gene function in corticogenesis at single cell resolution. We find
that the previously described growth-inhibitory Cdkn1c function is a non-cell-autonomous
one, acting on the whole organism. In contrast we reveal a growth-promoting cell-autonomous
Cdkn1c function which at the mechanistic level mediates radial glial progenitor
cell and nascent projection neuron survival. Strikingly, the growth-promoting
function of Cdkn1c is highly dosage sensitive but not subject to genomic imprinting.
Collectively, our results suggest that the Cdkn1c locus regulates cortical development
through distinct cell-autonomous and non-cell-autonomous mechanisms. More generally,
our study highlights the importance to probe the relative contributions of cell
intrinsic gene function and tissue-wide mechanisms to the overall phenotype.
acknowledged_ssus:
- _id: PreCl
article_number: '195'
article_processing_charge: No
article_type: original
author:
- first_name: Susanne
full_name: Laukoter, Susanne
id: 2D6B7A9A-F248-11E8-B48F-1D18A9856A87
last_name: Laukoter
orcid: 0000-0002-7903-3010
- first_name: Robert J
full_name: Beattie, Robert J
id: 2E26DF60-F248-11E8-B48F-1D18A9856A87
last_name: Beattie
orcid: 0000-0002-8483-8753
- first_name: Florian
full_name: Pauler, Florian
id: 48EA0138-F248-11E8-B48F-1D18A9856A87
last_name: Pauler
orcid: 0000-0002-7462-0048
- first_name: Nicole
full_name: Amberg, Nicole
id: 4CD6AAC6-F248-11E8-B48F-1D18A9856A87
last_name: Amberg
orcid: 0000-0002-3183-8207
- first_name: Keiichi I.
full_name: Nakayama, Keiichi I.
last_name: Nakayama
- first_name: Simon
full_name: Hippenmeyer, Simon
id: 37B36620-F248-11E8-B48F-1D18A9856A87
last_name: Hippenmeyer
orcid: 0000-0003-2279-1061
citation:
ama: Laukoter S, Beattie RJ, Pauler F, Amberg N, Nakayama KI, Hippenmeyer S. Imprinted
Cdkn1c genomic locus cell-autonomously promotes cell survival in cerebral cortex
development. Nature Communications. 2020;11. doi:10.1038/s41467-019-14077-2
apa: Laukoter, S., Beattie, R. J., Pauler, F., Amberg, N., Nakayama, K. I., &
Hippenmeyer, S. (2020). Imprinted Cdkn1c genomic locus cell-autonomously promotes
cell survival in cerebral cortex development. Nature Communications. Springer
Nature. https://doi.org/10.1038/s41467-019-14077-2
chicago: Laukoter, Susanne, Robert J Beattie, Florian Pauler, Nicole Amberg, Keiichi
I. Nakayama, and Simon Hippenmeyer. “Imprinted Cdkn1c Genomic Locus Cell-Autonomously
Promotes Cell Survival in Cerebral Cortex Development.” Nature Communications.
Springer Nature, 2020. https://doi.org/10.1038/s41467-019-14077-2.
ieee: S. Laukoter, R. J. Beattie, F. Pauler, N. Amberg, K. I. Nakayama, and S. Hippenmeyer,
“Imprinted Cdkn1c genomic locus cell-autonomously promotes cell survival in cerebral
cortex development,” Nature Communications, vol. 11. Springer Nature, 2020.
ista: Laukoter S, Beattie RJ, Pauler F, Amberg N, Nakayama KI, Hippenmeyer S. 2020.
Imprinted Cdkn1c genomic locus cell-autonomously promotes cell survival in cerebral
cortex development. Nature Communications. 11, 195.
mla: Laukoter, Susanne, et al. “Imprinted Cdkn1c Genomic Locus Cell-Autonomously
Promotes Cell Survival in Cerebral Cortex Development.” Nature Communications,
vol. 11, 195, Springer Nature, 2020, doi:10.1038/s41467-019-14077-2.
short: S. Laukoter, R.J. Beattie, F. Pauler, N. Amberg, K.I. Nakayama, S. Hippenmeyer,
Nature Communications 11 (2020).
date_created: 2020-01-11T10:42:48Z
date_published: 2020-01-10T00:00:00Z
date_updated: 2023-08-17T14:23:41Z
day: '10'
ddc:
- '570'
department:
- _id: SiHi
doi: 10.1038/s41467-019-14077-2
ec_funded: 1
external_id:
isi:
- '000551459000005'
file:
- access_level: open_access
checksum: ebf1ed522f4e0be8d94c939c1806a709
content_type: application/pdf
creator: dernst
date_created: 2020-01-13T07:42:31Z
date_updated: 2020-07-14T12:47:54Z
file_id: '7261'
file_name: 2020_NatureComm_Laukoter.pdf
file_size: 8063333
relation: main_file
file_date_updated: 2020-07-14T12:47:54Z
has_accepted_license: '1'
intvolume: ' 11'
isi: 1
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
project:
- _id: 268F8446-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: T0101031
name: Role of Eed in neural stem cell lineage progression
- _id: 264E56E2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: M02416
name: Molecular Mechanisms Regulating Gliogenesis in the Cerebral Cortex
- _id: 260018B0-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '725780'
name: Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development
- _id: 25D92700-B435-11E9-9278-68D0E5697425
grant_number: LS13-002
name: Mapping Cell-Type Specificity of the Genomic Imprintome in the Brain
publication: Nature Communications
publication_identifier:
issn:
- 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
link:
- description: News on IST Homepage
relation: press_release
url: https://ist.ac.at/en/news/new-function-for-potential-tumour-suppressor-in-brain-development/
scopus_import: '1'
status: public
title: Imprinted Cdkn1c genomic locus cell-autonomously promotes cell survival in
cerebral cortex development
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 11
year: '2020'
...
---
_id: '7258'
abstract:
- lang: eng
text: Many flows encountered in nature and applications are characterized by a chaotic
motion known as turbulence. Turbulent flows generate intense friction with pipe
walls and are responsible for considerable amounts of energy losses at world scale.
The nature of turbulent friction and techniques aimed at reducing it have been
subject of extensive research over the last century, but no definite answer has
been found yet. In this thesis we show that in pipes at moderate turbulent Reynolds
numbers friction is better described by the power law first introduced by Blasius
and not by the Prandtl–von Kármán formula. At higher Reynolds numbers, large scale
motions gradually become more important in the flow and can be related to the
change in scaling of friction. Next, we present a series of new techniques that
can relaminarize turbulence by suppressing a key mechanism that regenerates it
at walls, the lift–up effect. In addition, we investigate the process of turbulence
decay in several experiments and discuss the drag reduction potential. Finally,
we examine the behavior of friction under pulsating conditions inspired by the
human heart cycle and we show that under such circumstances turbulent friction
can be reduced to produce energy savings.
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Davide
full_name: Scarselli, Davide
id: 40315C30-F248-11E8-B48F-1D18A9856A87
last_name: Scarselli
orcid: 0000-0001-5227-4271
citation:
ama: Scarselli D. New approaches to reduce friction in turbulent pipe flow. 2020.
doi:10.15479/AT:ISTA:7258
apa: Scarselli, D. (2020). New approaches to reduce friction in turbulent pipe
flow. Institute of Science and Technology Austria. https://doi.org/10.15479/AT:ISTA:7258
chicago: Scarselli, Davide. “New Approaches to Reduce Friction in Turbulent Pipe
Flow.” Institute of Science and Technology Austria, 2020. https://doi.org/10.15479/AT:ISTA:7258.
ieee: D. Scarselli, “New approaches to reduce friction in turbulent pipe flow,”
Institute of Science and Technology Austria, 2020.
ista: Scarselli D. 2020. New approaches to reduce friction in turbulent pipe flow.
Institute of Science and Technology Austria.
mla: Scarselli, Davide. New Approaches to Reduce Friction in Turbulent Pipe Flow.
Institute of Science and Technology Austria, 2020, doi:10.15479/AT:ISTA:7258.
short: D. Scarselli, New Approaches to Reduce Friction in Turbulent Pipe Flow, Institute
of Science and Technology Austria, 2020.
date_created: 2020-01-12T16:07:26Z
date_published: 2020-01-13T00:00:00Z
date_updated: 2023-09-15T12:20:08Z
day: '13'
ddc:
- '532'
degree_awarded: PhD
department:
- _id: BjHo
doi: 10.15479/AT:ISTA:7258
ec_funded: 1
file:
- access_level: closed
checksum: 4df1ab24e9896635106adde5a54615bf
content_type: application/zip
creator: dscarsel
date_created: 2020-01-12T15:57:14Z
date_updated: 2021-01-13T23:30:05Z
embargo_to: open_access
file_id: '7259'
file_name: 2020_Scarselli_Thesis.zip
file_size: 26640830
relation: source_file
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checksum: 48659ab98e3414293c7a721385c2fd1c
content_type: application/pdf
creator: dscarsel
date_created: 2020-01-12T15:56:14Z
date_updated: 2021-01-13T23:30:05Z
embargo: 2021-01-12
file_id: '7260'
file_name: 2020_Scarselli_Thesis.pdf
file_size: 8515844
relation: main_file
file_date_updated: 2021-01-13T23:30:05Z
has_accepted_license: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: None
page: '174'
project:
- _id: 25152F3A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '306589'
name: Decoding the complexity of turbulence at its origin
- _id: 25104D44-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '737549'
name: Eliminating turbulence in oil pipelines
- _id: 25136C54-B435-11E9-9278-68D0E5697425
grant_number: HO 4393/1-2
name: Experimental studies of the turbulence transition and transport processes
in turbulent Taylor-Couette currents
publication_identifier:
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
record:
- id: '6228'
relation: part_of_dissertation
status: public
- id: '6486'
relation: part_of_dissertation
status: public
- id: '461'
relation: part_of_dissertation
status: public
- id: '422'
relation: part_of_dissertation
status: public
status: public
supervisor:
- first_name: Björn
full_name: Hof, Björn
id: 3A374330-F248-11E8-B48F-1D18A9856A87
last_name: Hof
orcid: 0000-0003-2057-2754
title: New approaches to reduce friction in turbulent pipe flow
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2020'
...
---
_id: '7262'
abstract:
- lang: eng
text: Advances in shape-morphing materials, such as hydrogels, shape-memory polymers
and light-responsive polymers have enabled prescribing self-directed deformations
of initially flat geometries. However, most proposed solutions evolve towards
a target geometry without considering time-dependent actuation paths. To achieve
more complex geometries and avoid self-collisions, it is critical to encode a
spatial and temporal shape evolution within the initially flat shell. Recent realizations
of time-dependent morphing are limited to the actuation of few, discrete hinges
and cannot form doubly curved surfaces. Here, we demonstrate a method for encoding
temporal shape evolution in architected shells that assume complex shapes and
doubly curved geometries. The shells are non-periodic tessellations of pre-stressed
contractile unit cells that soften in water at rates prescribed locally by mesostructure
geometry. The ensuing midplane contraction is coupled to the formation of encoded
curvatures. We propose an inverse design tool based on a data-driven model for
unit cells’ temporal responses.
article_number: '237'
article_processing_charge: No
article_type: original
author:
- first_name: Ruslan
full_name: Guseinov, Ruslan
id: 3AB45EE2-F248-11E8-B48F-1D18A9856A87
last_name: Guseinov
orcid: 0000-0001-9819-5077
- first_name: Connor
full_name: McMahan, Connor
last_name: McMahan
- first_name: Jesus
full_name: Perez Rodriguez, Jesus
id: 2DC83906-F248-11E8-B48F-1D18A9856A87
last_name: Perez Rodriguez
- first_name: Chiara
full_name: Daraio, Chiara
last_name: Daraio
- first_name: Bernd
full_name: Bickel, Bernd
id: 49876194-F248-11E8-B48F-1D18A9856A87
last_name: Bickel
orcid: 0000-0001-6511-9385
citation:
ama: Guseinov R, McMahan C, Perez Rodriguez J, Daraio C, Bickel B. Programming temporal
morphing of self-actuated shells. Nature Communications. 2020;11. doi:10.1038/s41467-019-14015-2
apa: Guseinov, R., McMahan, C., Perez Rodriguez, J., Daraio, C., & Bickel, B.
(2020). Programming temporal morphing of self-actuated shells. Nature Communications.
Springer Nature. https://doi.org/10.1038/s41467-019-14015-2
chicago: Guseinov, Ruslan, Connor McMahan, Jesus Perez Rodriguez, Chiara Daraio,
and Bernd Bickel. “Programming Temporal Morphing of Self-Actuated Shells.” Nature
Communications. Springer Nature, 2020. https://doi.org/10.1038/s41467-019-14015-2.
ieee: R. Guseinov, C. McMahan, J. Perez Rodriguez, C. Daraio, and B. Bickel, “Programming
temporal morphing of self-actuated shells,” Nature Communications, vol.
11. Springer Nature, 2020.
ista: Guseinov R, McMahan C, Perez Rodriguez J, Daraio C, Bickel B. 2020. Programming
temporal morphing of self-actuated shells. Nature Communications. 11, 237.
mla: Guseinov, Ruslan, et al. “Programming Temporal Morphing of Self-Actuated Shells.”
Nature Communications, vol. 11, 237, Springer Nature, 2020, doi:10.1038/s41467-019-14015-2.
short: R. Guseinov, C. McMahan, J. Perez Rodriguez, C. Daraio, B. Bickel, Nature
Communications 11 (2020).
date_created: 2020-01-13T16:54:26Z
date_published: 2020-01-13T00:00:00Z
date_updated: 2024-02-21T12:45:02Z
day: '13'
ddc:
- '000'
department:
- _id: BeBi
doi: 10.1038/s41467-019-14015-2
ec_funded: 1
external_id:
isi:
- '000511916800015'
file:
- access_level: open_access
checksum: 7db23fef2f4cda712f17f1004116ddff
content_type: application/pdf
creator: rguseino
date_created: 2020-01-15T14:35:34Z
date_updated: 2020-07-14T12:47:55Z
file_id: '7336'
file_name: 2020_NatureComm_Guseinov.pdf
file_size: 1315270
relation: main_file
file_date_updated: 2020-07-14T12:47:55Z
has_accepted_license: '1'
intvolume: ' 11'
isi: 1
keyword:
- Design
- Synthesis and processing
- Mechanical engineering
- Polymers
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
- _id: 24F9549A-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '715767'
name: 'MATERIALIZABLE: Intelligent fabrication-oriented Computational Design and
Modeling'
publication: Nature Communications
publication_identifier:
issn:
- 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
link:
- description: News on IST Homepage
relation: press_release
url: https://ist.ac.at/en/news/geometry-meets-time/
record:
- id: '8366'
relation: dissertation_contains
status: public
- id: '7154'
relation: research_data
status: public
scopus_import: '1'
status: public
title: Programming temporal morphing of self-actuated shells
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 11
year: '2020'
...
---
_id: '7272'
abstract:
- lang: eng
text: "Many systems rely on optimistic concurrent search trees for multi-core scalability.
In principle, optimistic trees have a simple performance story: searches are read-only
and so run in parallel, with writes to shared memory occurring only when modifying
the data structure. However, this paper shows that in practice, obtaining the
full performance benefits of optimistic search trees is not so simple.\r\n\r\nWe
focus on optimistic binary search trees (BSTs) and perform a detailed performance
analysis of 10 state-of-the-art BSTs on large scale x86-64 hardware, using both
microbenchmarks and an in-memory database system. We find and explain significant
unexpected performance differences between BSTs with similar tree structure and
search implementations, which we trace to subtle performance-degrading interactions
of BSTs with systems software and hardware subsystems. We further derive a prescriptive
approach to avoid this performance degradation, as well as algorithmic insights
on optimistic BST design. Our work underlines the gap between the theory and practice
of multi-core performance, and calls for further research to help bridge this
gap."
article_processing_charge: No
author:
- first_name: Maya
full_name: Arbel-Raviv, Maya
last_name: Arbel-Raviv
- first_name: Trevor A
full_name: Brown, Trevor A
id: 3569F0A0-F248-11E8-B48F-1D18A9856A87
last_name: Brown
- first_name: Adam
full_name: Morrison, Adam
last_name: Morrison
citation:
ama: 'Arbel-Raviv M, Brown TA, Morrison A. Getting to the root of concurrent binary
search tree performance. In: Proceedings of the 2018 USENIX Annual Technical
Conference. USENIX Association; 2020:295-306.'
apa: 'Arbel-Raviv, M., Brown, T. A., & Morrison, A. (2020). Getting to the root
of concurrent binary search tree performance. In Proceedings of the 2018 USENIX
Annual Technical Conference (pp. 295–306). Boston, MA, United States: USENIX
Association.'
chicago: Arbel-Raviv, Maya, Trevor A Brown, and Adam Morrison. “Getting to the Root
of Concurrent Binary Search Tree Performance.” In Proceedings of the 2018 USENIX
Annual Technical Conference, 295–306. USENIX Association, 2020.
ieee: M. Arbel-Raviv, T. A. Brown, and A. Morrison, “Getting to the root of concurrent
binary search tree performance,” in Proceedings of the 2018 USENIX Annual Technical
Conference, Boston, MA, United States, 2020, pp. 295–306.
ista: 'Arbel-Raviv M, Brown TA, Morrison A. 2020. Getting to the root of concurrent
binary search tree performance. Proceedings of the 2018 USENIX Annual Technical
Conference. USENIX: Annual Technical Conference, 295–306.'
mla: Arbel-Raviv, Maya, et al. “Getting to the Root of Concurrent Binary Search
Tree Performance.” Proceedings of the 2018 USENIX Annual Technical Conference,
USENIX Association, 2020, pp. 295–306.
short: M. Arbel-Raviv, T.A. Brown, A. Morrison, in:, Proceedings of the 2018 USENIX
Annual Technical Conference, USENIX Association, 2020, pp. 295–306.
conference:
end_date: 2018-07-13
location: Boston, MA, United States
name: 'USENIX: Annual Technical Conference'
start_date: 2018-07-11
date_created: 2020-01-14T07:27:08Z
date_published: 2020-01-01T00:00:00Z
date_updated: 2021-01-11T15:25:48Z
day: '01'
ddc:
- '000'
department:
- _id: DaAl
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.usenix.org/system/files/conference/atc18/atc18-arbel-raviv.pdf
month: '01'
oa: 1
oa_version: Published Version
page: 295-306
project:
- _id: 26450934-B435-11E9-9278-68D0E5697425
name: NSERC Postdoctoral fellowship
publication: Proceedings of the 2018 USENIX Annual Technical Conference
publication_identifier:
isbn:
- '9781939133021'
publication_status: published
publisher: USENIX Association
quality_controlled: '1'
scopus_import: '1'
status: public
title: Getting to the root of concurrent binary search tree performance
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2020'
...
---
_id: '7339'
abstract:
- lang: eng
text: Cytoskeletal filaments such as microtubules (MTs) and filamentous actin (F-actin)
dynamically support cell structure and functions. In central presynaptic terminals,
F-actin is expressed along the release edge and reportedly plays diverse functional
roles, but whether axonal MTs extend deep into terminals and play any physiological
role remains controversial. At the calyx of Held in rats of either sex, confocal
and high-resolution microscopy revealed that MTs enter deep into presynaptic terminal
swellings and partially colocalize with a subset of synaptic vesicles (SVs). Electrophysiological
analysis demonstrated that depolymerization of MTs specifically prolonged the
slow-recovery time component of EPSCs from short-term depression induced by a
train of high-frequency stimulation, whereas depolymerization of F-actin specifically
prolonged the fast-recovery component. In simultaneous presynaptic and postsynaptic
action potential recordings, depolymerization of MTs or F-actin significantly
impaired the fidelity of high-frequency neurotransmission. We conclude that MTs
and F-actin differentially contribute to slow and fast SV replenishment, thereby
maintaining high-frequency neurotransmission.
article_processing_charge: No
article_type: original
author:
- first_name: Lashmi
full_name: Piriya Ananda Babu, Lashmi
last_name: Piriya Ananda Babu
- first_name: Han Ying
full_name: Wang, Han Ying
last_name: Wang
- first_name: Kohgaku
full_name: Eguchi, Kohgaku
id: 2B7846DC-F248-11E8-B48F-1D18A9856A87
last_name: Eguchi
orcid: 0000-0002-6170-2546
- first_name: Laurent
full_name: Guillaud, Laurent
last_name: Guillaud
- first_name: Tomoyuki
full_name: Takahashi, Tomoyuki
last_name: Takahashi
citation:
ama: Piriya Ananda Babu L, Wang HY, Eguchi K, Guillaud L, Takahashi T. Microtubule
and actin differentially regulate synaptic vesicle cycling to maintain high-frequency
neurotransmission. Journal of neuroscience. 2020;40(1):131-142. doi:10.1523/JNEUROSCI.1571-19.2019
apa: Piriya Ananda Babu, L., Wang, H. Y., Eguchi, K., Guillaud, L., & Takahashi,
T. (2020). Microtubule and actin differentially regulate synaptic vesicle cycling
to maintain high-frequency neurotransmission. Journal of Neuroscience.
Society for Neuroscience. https://doi.org/10.1523/JNEUROSCI.1571-19.2019
chicago: Piriya Ananda Babu, Lashmi, Han Ying Wang, Kohgaku Eguchi, Laurent Guillaud,
and Tomoyuki Takahashi. “Microtubule and Actin Differentially Regulate Synaptic
Vesicle Cycling to Maintain High-Frequency Neurotransmission.” Journal of Neuroscience.
Society for Neuroscience, 2020. https://doi.org/10.1523/JNEUROSCI.1571-19.2019.
ieee: L. Piriya Ananda Babu, H. Y. Wang, K. Eguchi, L. Guillaud, and T. Takahashi,
“Microtubule and actin differentially regulate synaptic vesicle cycling to maintain
high-frequency neurotransmission,” Journal of neuroscience, vol. 40, no.
1. Society for Neuroscience, pp. 131–142, 2020.
ista: Piriya Ananda Babu L, Wang HY, Eguchi K, Guillaud L, Takahashi T. 2020. Microtubule
and actin differentially regulate synaptic vesicle cycling to maintain high-frequency
neurotransmission. Journal of neuroscience. 40(1), 131–142.
mla: Piriya Ananda Babu, Lashmi, et al. “Microtubule and Actin Differentially Regulate
Synaptic Vesicle Cycling to Maintain High-Frequency Neurotransmission.” Journal
of Neuroscience, vol. 40, no. 1, Society for Neuroscience, 2020, pp. 131–42,
doi:10.1523/JNEUROSCI.1571-19.2019.
short: L. Piriya Ananda Babu, H.Y. Wang, K. Eguchi, L. Guillaud, T. Takahashi, Journal
of Neuroscience 40 (2020) 131–142.
date_created: 2020-01-19T23:00:38Z
date_published: 2020-01-02T00:00:00Z
date_updated: 2023-08-17T14:25:23Z
day: '02'
ddc:
- '570'
department:
- _id: RySh
doi: 10.1523/JNEUROSCI.1571-19.2019
external_id:
isi:
- '000505167600013'
pmid:
- '31767677'
file:
- access_level: open_access
checksum: 92f5e8a47f454fc131fb94cd7f106e60
content_type: application/pdf
creator: dernst
date_created: 2020-01-20T14:44:10Z
date_updated: 2020-07-14T12:47:56Z
file_id: '7345'
file_name: 2020_JourNeuroscience_Piriya.pdf
file_size: 4460781
relation: main_file
file_date_updated: 2020-07-14T12:47:56Z
has_accepted_license: '1'
intvolume: ' 40'
isi: 1
issue: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 131-142
pmid: 1
publication: Journal of neuroscience
publication_identifier:
eissn:
- '15292401'
publication_status: published
publisher: Society for Neuroscience
quality_controlled: '1'
scopus_import: '1'
status: public
title: Microtubule and actin differentially regulate synaptic vesicle cycling to maintain
high-frequency neurotransmission
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 40
year: '2020'
...
---
_id: '7343'
abstract:
- lang: eng
text: Coinfections with multiple pathogens can result in complex within‐host dynamics
affecting virulence and transmission. While multiple infections are intensively
studied in solitary hosts, it is so far unresolved how social host interactions
interfere with pathogen competition, and if this depends on coinfection diversity.
We studied how the collective disease defences of ants – their social immunity
– influence pathogen competition in coinfections of same or different fungal pathogen
species. Social immunity reduced virulence for all pathogen combinations, but
interfered with spore production only in different‐species coinfections. Here,
it decreased overall pathogen sporulation success while increasing co‐sporulation
on individual cadavers and maintaining a higher pathogen diversity at the community
level. Mathematical modelling revealed that host sanitary care alone can modulate
competitive outcomes between pathogens, giving advantage to fast‐germinating,
thus less grooming‐sensitive ones. Host social interactions can hence modulate
infection dynamics in coinfected group members, thereby altering pathogen communities
at the host level and population level.
acknowledged_ssus:
- _id: LifeSc
acknowledgement: "We thank Bernhardt Steinwender and Jorgen Eilenberg for the fungal
strains, Xavier Espadaler, Mireia Diaz, Christiane Wanke, Lumi Viljakainen and the
Social Immunity Team at IST Austria, for help with ant collection, and Wanda Gorecka
and Gertraud Stift of the IST Austria Life Science Facility for technical support.
We are thankful to Dieter Ebert for input at all stages of the project, Roger Mundry
for statistical advice, Hinrich Schulenburg, Paul Schmid-Hempel, Yuko\r\nUlrich
and Joachim Kurtz for project discussion, Bor Kavcic for advice on growth curves,
Marcus Roper for advice on modelling work and comments on the manuscript, as well
as Marjon de Vos, Weini Huang and the Social Immunity Team for comments on the manuscript.\r\nThis
study was funded by the German Research Foundation (DFG) within the Priority Programme
1399 Host-parasite Coevolution (CR 118/3 to S.C.) and the People Programme\r\n(Marie
Curie Actions) of the European Union’s Seventh Framework Programme (FP7/2007-2013)
under REA grant agreement no 291734 (ISTFELLOW to B.M.). "
article_processing_charge: Yes (via OA deal)
article_type: letter_note
author:
- first_name: Barbara
full_name: Milutinovic, Barbara
id: 2CDC32B8-F248-11E8-B48F-1D18A9856A87
last_name: Milutinovic
orcid: 0000-0002-8214-4758
- first_name: Miriam
full_name: Stock, Miriam
id: 42462816-F248-11E8-B48F-1D18A9856A87
last_name: Stock
- first_name: Anna V
full_name: Grasse, Anna V
id: 406F989C-F248-11E8-B48F-1D18A9856A87
last_name: Grasse
- first_name: Elisabeth
full_name: Naderlinger, Elisabeth
id: 31757262-F248-11E8-B48F-1D18A9856A87
last_name: Naderlinger
- first_name: Christian
full_name: Hilbe, Christian
id: 2FDF8F3C-F248-11E8-B48F-1D18A9856A87
last_name: Hilbe
orcid: 0000-0001-5116-955X
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
citation:
ama: Milutinovic B, Stock M, Grasse AV, Naderlinger E, Hilbe C, Cremer S. Social
immunity modulates competition between coinfecting pathogens. Ecology Letters.
2020;23(3):565-574. doi:10.1111/ele.13458
apa: Milutinovic, B., Stock, M., Grasse, A. V., Naderlinger, E., Hilbe, C., &
Cremer, S. (2020). Social immunity modulates competition between coinfecting pathogens.
Ecology Letters. Wiley. https://doi.org/10.1111/ele.13458
chicago: Milutinovic, Barbara, Miriam Stock, Anna V Grasse, Elisabeth Naderlinger,
Christian Hilbe, and Sylvia Cremer. “Social Immunity Modulates Competition between
Coinfecting Pathogens.” Ecology Letters. Wiley, 2020. https://doi.org/10.1111/ele.13458.
ieee: B. Milutinovic, M. Stock, A. V. Grasse, E. Naderlinger, C. Hilbe, and S. Cremer,
“Social immunity modulates competition between coinfecting pathogens,” Ecology
Letters, vol. 23, no. 3. Wiley, pp. 565–574, 2020.
ista: Milutinovic B, Stock M, Grasse AV, Naderlinger E, Hilbe C, Cremer S. 2020.
Social immunity modulates competition between coinfecting pathogens. Ecology Letters.
23(3), 565–574.
mla: Milutinovic, Barbara, et al. “Social Immunity Modulates Competition between
Coinfecting Pathogens.” Ecology Letters, vol. 23, no. 3, Wiley, 2020, pp.
565–74, doi:10.1111/ele.13458.
short: B. Milutinovic, M. Stock, A.V. Grasse, E. Naderlinger, C. Hilbe, S. Cremer,
Ecology Letters 23 (2020) 565–574.
date_created: 2020-01-20T13:32:12Z
date_published: 2020-03-01T00:00:00Z
date_updated: 2023-09-05T16:04:49Z
day: '01'
ddc:
- '570'
department:
- _id: SyCr
- _id: KrCh
doi: 10.1111/ele.13458
ec_funded: 1
external_id:
isi:
- '000507515900001'
file:
- access_level: open_access
checksum: 0cd8be386fa219db02845b7c3991ce04
content_type: application/pdf
creator: dernst
date_created: 2020-11-19T11:27:10Z
date_updated: 2020-11-19T11:27:10Z
file_id: '8776'
file_name: 2020_EcologyLetters_Milutinovic.pdf
file_size: 561749
relation: main_file
success: 1
file_date_updated: 2020-11-19T11:27:10Z
has_accepted_license: '1'
intvolume: ' 23'
isi: 1
issue: '3'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 565-574
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
- _id: 25DAF0B2-B435-11E9-9278-68D0E5697425
grant_number: CR-118/3-1
name: Host-Parasite Coevolution
publication: Ecology Letters
publication_identifier:
eissn:
- 1461-0248
issn:
- 1461-023X
publication_status: published
publisher: Wiley
quality_controlled: '1'
related_material:
link:
- description: News on IST Homepage
relation: press_release
url: https://ist.ac.at/en/news/social-ants-shapes-disease-outcome/
record:
- id: '13060'
relation: research_data
status: public
scopus_import: '1'
status: public
title: Social immunity modulates competition between coinfecting pathogens
tmp:
image: /images/cc_by_nc.png
legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
short: CC BY-NC (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 23
year: '2020'
...
---
_id: '7346'
abstract:
- lang: eng
text: 'The Price of Anarchy (PoA) is a well-established game-theoretic concept to
shed light on coordination issues arising in open distributed systems. Leaving
agents to selfishly optimize comes with the risk of ending up in sub-optimal states
(in terms of performance and/or costs), compared to a centralized system design.
However, the PoA relies on strong assumptions about agents'' rationality (e.g.,
resources and information) and interactions, whereas in many distributed systems
agents interact locally with bounded resources. They do so repeatedly over time
(in contrast to "one-shot games"), and their strategies may evolve. Using a more
realistic evolutionary game model, this paper introduces a realized evolutionary
Price of Anarchy (ePoA). The ePoA allows an exploration of equilibrium selection
in dynamic distributed systems with multiple equilibria, based on local interactions
of simple memoryless agents. Considering a fundamental game related to virus propagation
on networks, we present analytical bounds on the ePoA in basic network topologies
and for different strategy update dynamics. In particular, deriving stationary
distributions of the stochastic evolutionary process, we find that the Nash equilibria
are not always the most abundant states, and that different processes can feature
significant off-equilibrium behavior, leading to a significantly higher ePoA compared
to the PoA studied traditionally in the literature. '
alternative_title:
- LIPIcs
article_number: '21'
article_processing_charge: No
arxiv: 1
author:
- first_name: Laura
full_name: Schmid, Laura
id: 38B437DE-F248-11E8-B48F-1D18A9856A87
last_name: Schmid
orcid: 0000-0002-6978-7329
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Stefan
full_name: Schmid, Stefan
last_name: Schmid
citation:
ama: 'Schmid L, Chatterjee K, Schmid S. The evolutionary price of anarchy: Locally
bounded agents in a dynamic virus game. In: Proceedings of the 23rd International
Conference on Principles of Distributed Systems. Vol 153. Schloss Dagstuhl
- Leibniz-Zentrum für Informatik; 2020. doi:10.4230/LIPIcs.OPODIS.2019.21'
apa: 'Schmid, L., Chatterjee, K., & Schmid, S. (2020). The evolutionary price
of anarchy: Locally bounded agents in a dynamic virus game. In Proceedings
of the 23rd International Conference on Principles of Distributed Systems
(Vol. 153). Neuchâtel, Switzerland: Schloss Dagstuhl - Leibniz-Zentrum für Informatik.
https://doi.org/10.4230/LIPIcs.OPODIS.2019.21'
chicago: 'Schmid, Laura, Krishnendu Chatterjee, and Stefan Schmid. “The Evolutionary
Price of Anarchy: Locally Bounded Agents in a Dynamic Virus Game.” In Proceedings
of the 23rd International Conference on Principles of Distributed Systems,
Vol. 153. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2020. https://doi.org/10.4230/LIPIcs.OPODIS.2019.21.'
ieee: 'L. Schmid, K. Chatterjee, and S. Schmid, “The evolutionary price of anarchy:
Locally bounded agents in a dynamic virus game,” in Proceedings of the 23rd
International Conference on Principles of Distributed Systems, Neuchâtel,
Switzerland, 2020, vol. 153.'
ista: 'Schmid L, Chatterjee K, Schmid S. 2020. The evolutionary price of anarchy:
Locally bounded agents in a dynamic virus game. Proceedings of the 23rd International
Conference on Principles of Distributed Systems. OPODIS: International Conference
on Principles of Distributed Systems, LIPIcs, vol. 153, 21.'
mla: 'Schmid, Laura, et al. “The Evolutionary Price of Anarchy: Locally Bounded
Agents in a Dynamic Virus Game.” Proceedings of the 23rd International Conference
on Principles of Distributed Systems, vol. 153, 21, Schloss Dagstuhl - Leibniz-Zentrum
für Informatik, 2020, doi:10.4230/LIPIcs.OPODIS.2019.21.'
short: L. Schmid, K. Chatterjee, S. Schmid, in:, Proceedings of the 23rd International
Conference on Principles of Distributed Systems, Schloss Dagstuhl - Leibniz-Zentrum
für Informatik, 2020.
conference:
end_date: 2019-12-19
location: Neuchâtel, Switzerland
name: 'OPODIS: International Conference on Principles of Distributed Systems'
start_date: 2019-12-17
date_created: 2020-01-21T16:00:26Z
date_published: 2020-02-10T00:00:00Z
date_updated: 2023-02-23T13:05:49Z
day: '10'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.4230/LIPIcs.OPODIS.2019.21
external_id:
arxiv:
- '1906.00110'
file:
- access_level: open_access
checksum: 9a91916ac2c21ab42458fcda39ef0b8d
content_type: application/pdf
creator: dernst
date_created: 2020-03-23T09:14:06Z
date_updated: 2020-07-14T12:47:56Z
file_id: '7608'
file_name: 2019_LIPIcS_Schmid.pdf
file_size: 630752
relation: main_file
file_date_updated: 2020-07-14T12:47:56Z
has_accepted_license: '1'
intvolume: ' 153'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Preprint
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
publication: Proceedings of the 23rd International Conference on Principles of Distributed
Systems
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'The evolutionary price of anarchy: Locally bounded agents in a dynamic virus
game'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 153
year: '2020'
...
---
_id: '7348'
abstract:
- lang: eng
text: 'The monitoring of event frequencies can be used to recognize behavioral anomalies,
to identify trends, and to deduce or discard hypotheses about the underlying system.
For example, the performance of a web server may be monitored based on the ratio
of the total count of requests from the least and most active clients. Exact frequency
monitoring, however, can be prohibitively expensive; in the above example it would
require as many counters as there are clients. In this paper, we propose the efficient
probabilistic monitoring of common frequency properties, including the mode (i.e.,
the most common event) and the median of an event sequence. We define a logic
to express composite frequency properties as a combination of atomic frequency
properties. Our main contribution is an algorithm that, under suitable probabilistic
assumptions, can be used to monitor these important frequency properties with
four counters, independent of the number of different events. Our algorithm samples
longer and longer subwords of an infinite event sequence. We prove the almost-sure
convergence of our algorithm by generalizing ergodic theory from increasing-length
prefixes to increasing-length subwords of an infinite sequence. A similar algorithm
could be used to learn a connected Markov chain of a given structure from observing
its outputs, to arbitrary precision, for a given confidence. '
alternative_title:
- LIPIcs
article_number: '20'
article_processing_charge: No
arxiv: 1
author:
- first_name: Thomas
full_name: Ferrere, Thomas
id: 40960E6E-F248-11E8-B48F-1D18A9856A87
last_name: Ferrere
orcid: 0000-0001-5199-3143
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Bernhard
full_name: Kragl, Bernhard
id: 320FC952-F248-11E8-B48F-1D18A9856A87
last_name: Kragl
orcid: 0000-0001-7745-9117
citation:
ama: 'Ferrere T, Henzinger TA, Kragl B. Monitoring event frequencies. In: 28th
EACSL Annual Conference on Computer Science Logic. Vol 152. Schloss Dagstuhl
- Leibniz-Zentrum für Informatik; 2020. doi:10.4230/LIPIcs.CSL.2020.20'
apa: 'Ferrere, T., Henzinger, T. A., & Kragl, B. (2020). Monitoring event frequencies.
In 28th EACSL Annual Conference on Computer Science Logic (Vol. 152). Barcelona,
Spain: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. https://doi.org/10.4230/LIPIcs.CSL.2020.20'
chicago: Ferrere, Thomas, Thomas A Henzinger, and Bernhard Kragl. “Monitoring Event
Frequencies.” In 28th EACSL Annual Conference on Computer Science Logic,
Vol. 152. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2020. https://doi.org/10.4230/LIPIcs.CSL.2020.20.
ieee: T. Ferrere, T. A. Henzinger, and B. Kragl, “Monitoring event frequencies,”
in 28th EACSL Annual Conference on Computer Science Logic, Barcelona, Spain,
2020, vol. 152.
ista: 'Ferrere T, Henzinger TA, Kragl B. 2020. Monitoring event frequencies. 28th
EACSL Annual Conference on Computer Science Logic. CSL: Computer Science Logic,
LIPIcs, vol. 152, 20.'
mla: Ferrere, Thomas, et al. “Monitoring Event Frequencies.” 28th EACSL Annual
Conference on Computer Science Logic, vol. 152, 20, Schloss Dagstuhl - Leibniz-Zentrum
für Informatik, 2020, doi:10.4230/LIPIcs.CSL.2020.20.
short: T. Ferrere, T.A. Henzinger, B. Kragl, in:, 28th EACSL Annual Conference on
Computer Science Logic, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2020.
conference:
end_date: 2020-01-16
location: Barcelona, Spain
name: 'CSL: Computer Science Logic'
start_date: 2020-01-13
date_created: 2020-01-21T11:22:21Z
date_published: 2020-01-15T00:00:00Z
date_updated: 2021-01-12T08:13:12Z
day: '15'
ddc:
- '000'
department:
- _id: ToHe
doi: 10.4230/LIPIcs.CSL.2020.20
external_id:
arxiv:
- '1910.06097'
file:
- access_level: open_access
checksum: b9a691d658d075c6369d3304d17fb818
content_type: application/pdf
creator: bkragl
date_created: 2020-01-21T11:21:04Z
date_updated: 2020-07-14T12:47:56Z
file_id: '7349'
file_name: main.pdf
file_size: 617206
relation: main_file
file_date_updated: 2020-07-14T12:47:56Z
has_accepted_license: '1'
intvolume: ' 152'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
project:
- _id: 25F2ACDE-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11402-N23
name: Rigorous Systems Engineering
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z211
name: The Wittgenstein Prize
publication: 28th EACSL Annual Conference on Computer Science Logic
publication_identifier:
isbn:
- '9783959771320'
issn:
- 1868-8969
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
quality_controlled: '1'
scopus_import: 1
status: public
title: Monitoring event frequencies
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 152
year: '2020'
...
---
_id: '7350'
abstract:
- lang: eng
text: The ability to sense environmental temperature and to coordinate growth and
development accordingly, is critical to the reproductive success of plants. Flowering
time is regulated at the level of gene expression by a complex network of factors
that integrate environmental and developmental cues. One of the main players,
involved in modulating flowering time in response to changes in ambient temperature
is FLOWERING LOCUS M (FLM). FLM transcripts can undergo extensive alternative
splicing producing multiple variants, of which FLM-β and FLM-δ are the most representative.
While FLM-β codes for the flowering repressor FLM protein, translation of FLM-δ
has the opposite effect on flowering. Here we show that the cyclin-dependent kinase
G2 (CDKG2), together with its cognate cyclin, CYCLYN L1 (CYCL1) affects the alternative
splicing of FLM, balancing the levels of FLM-β and FLM-δ across the ambient temperature
range. In the absence of the CDKG2/CYCL1 complex, FLM-β expression is reduced
while FLM-δ is increased in a temperature dependent manner and these changes are
associated with an early flowering phenotype in the cdkg2 mutant lines. In addition,
we found that transcript variants retaining the full FLM intron 1 are sequestered
in the cell nucleus. Strikingly, FLM intron 1 splicing is also regulated by CDKG2/CYCL1.
Our results provide evidence that temperature and CDKs regulate the alternative
splicing of FLM, contributing to flowering time definition.
article_number: '1680'
article_processing_charge: No
article_type: original
author:
- first_name: Candida
full_name: Nibau, Candida
last_name: Nibau
- first_name: Marçal
full_name: Gallemi, Marçal
id: 460C6802-F248-11E8-B48F-1D18A9856A87
last_name: Gallemi
orcid: 0000-0003-4675-6893
- first_name: Despoina
full_name: Dadarou, Despoina
last_name: Dadarou
- first_name: John H.
full_name: Doonan, John H.
last_name: Doonan
- first_name: Nicola
full_name: Cavallari, Nicola
id: 457160E6-F248-11E8-B48F-1D18A9856A87
last_name: Cavallari
citation:
ama: Nibau C, Gallemi M, Dadarou D, Doonan JH, Cavallari N. Thermo-sensitive alternative
splicing of FLOWERING LOCUS M is modulated by cyclin-dependent kinase G2. Frontiers
in Plant Science. 2020;10. doi:10.3389/fpls.2019.01680
apa: Nibau, C., Gallemi, M., Dadarou, D., Doonan, J. H., & Cavallari, N. (2020).
Thermo-sensitive alternative splicing of FLOWERING LOCUS M is modulated by cyclin-dependent
kinase G2. Frontiers in Plant Science. Frontiers Media. https://doi.org/10.3389/fpls.2019.01680
chicago: Nibau, Candida, Marçal Gallemi, Despoina Dadarou, John H. Doonan, and Nicola
Cavallari. “Thermo-Sensitive Alternative Splicing of FLOWERING LOCUS M Is Modulated
by Cyclin-Dependent Kinase G2.” Frontiers in Plant Science. Frontiers Media,
2020. https://doi.org/10.3389/fpls.2019.01680.
ieee: C. Nibau, M. Gallemi, D. Dadarou, J. H. Doonan, and N. Cavallari, “Thermo-sensitive
alternative splicing of FLOWERING LOCUS M is modulated by cyclin-dependent kinase
G2,” Frontiers in Plant Science, vol. 10. Frontiers Media, 2020.
ista: Nibau C, Gallemi M, Dadarou D, Doonan JH, Cavallari N. 2020. Thermo-sensitive
alternative splicing of FLOWERING LOCUS M is modulated by cyclin-dependent kinase
G2. Frontiers in Plant Science. 10, 1680.
mla: Nibau, Candida, et al. “Thermo-Sensitive Alternative Splicing of FLOWERING
LOCUS M Is Modulated by Cyclin-Dependent Kinase G2.” Frontiers in Plant Science,
vol. 10, 1680, Frontiers Media, 2020, doi:10.3389/fpls.2019.01680.
short: C. Nibau, M. Gallemi, D. Dadarou, J.H. Doonan, N. Cavallari, Frontiers in
Plant Science 10 (2020).
date_created: 2020-01-22T15:23:57Z
date_published: 2020-01-22T00:00:00Z
date_updated: 2023-08-17T14:21:45Z
day: '22'
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publication: Frontiers in Plant Science
publication_identifier:
issn:
- 1664-462X
publication_status: published
publisher: Frontiers Media
quality_controlled: '1'
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status: public
title: Thermo-sensitive alternative splicing of FLOWERING LOCUS M is modulated by
cyclin-dependent kinase G2
tmp:
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legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
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---
_id: '7364'
abstract:
- lang: eng
text: We present nsCouette, a highly scalable software tool to solve the Navier–Stokes
equations for incompressible fluid flow between differentially heated and independently
rotating, concentric cylinders. It is based on a pseudospectral spatial discretization
and dynamic time-stepping. It is implemented in modern Fortran with a hybrid MPI-OpenMP
parallelization scheme and thus designed to compute turbulent flows at high Reynolds
and Rayleigh numbers. An additional GPU implementation (C-CUDA) for intermediate
problem sizes and a version for pipe flow (nsPipe) are also provided.
article_number: '100395'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Jose M
full_name: Lopez Alonso, Jose M
id: 40770848-F248-11E8-B48F-1D18A9856A87
last_name: Lopez Alonso
orcid: 0000-0002-0384-2022
- first_name: Daniel
full_name: Feldmann, Daniel
last_name: Feldmann
- first_name: Markus
full_name: Rampp, Markus
last_name: Rampp
- first_name: Alberto
full_name: Vela-Martín, Alberto
last_name: Vela-Martín
- first_name: Liang
full_name: Shi, Liang
id: 374A3F1A-F248-11E8-B48F-1D18A9856A87
last_name: Shi
- first_name: Marc
full_name: Avila, Marc
last_name: Avila
citation:
ama: Lopez Alonso JM, Feldmann D, Rampp M, Vela-Martín A, Shi L, Avila M. nsCouette
– A high-performance code for direct numerical simulations of turbulent Taylor–Couette
flow. SoftwareX. 2020;11. doi:10.1016/j.softx.2019.100395
apa: Lopez Alonso, J. M., Feldmann, D., Rampp, M., Vela-Martín, A., Shi, L., &
Avila, M. (2020). nsCouette – A high-performance code for direct numerical simulations
of turbulent Taylor–Couette flow. SoftwareX. Elsevier. https://doi.org/10.1016/j.softx.2019.100395
chicago: Lopez Alonso, Jose M, Daniel Feldmann, Markus Rampp, Alberto Vela-Martín,
Liang Shi, and Marc Avila. “NsCouette – A High-Performance Code for Direct Numerical
Simulations of Turbulent Taylor–Couette Flow.” SoftwareX. Elsevier, 2020.
https://doi.org/10.1016/j.softx.2019.100395.
ieee: J. M. Lopez Alonso, D. Feldmann, M. Rampp, A. Vela-Martín, L. Shi, and M.
Avila, “nsCouette – A high-performance code for direct numerical simulations of
turbulent Taylor–Couette flow,” SoftwareX, vol. 11. Elsevier, 2020.
ista: Lopez Alonso JM, Feldmann D, Rampp M, Vela-Martín A, Shi L, Avila M. 2020.
nsCouette – A high-performance code for direct numerical simulations of turbulent
Taylor–Couette flow. SoftwareX. 11, 100395.
mla: Lopez Alonso, Jose M., et al. “NsCouette – A High-Performance Code for Direct
Numerical Simulations of Turbulent Taylor–Couette Flow.” SoftwareX, vol.
11, 100395, Elsevier, 2020, doi:10.1016/j.softx.2019.100395.
short: J.M. Lopez Alonso, D. Feldmann, M. Rampp, A. Vela-Martín, L. Shi, M. Avila,
SoftwareX 11 (2020).
date_created: 2020-01-26T23:00:35Z
date_published: 2020-01-17T00:00:00Z
date_updated: 2023-08-17T14:29:59Z
day: '17'
ddc:
- '000'
department:
- _id: BjHo
doi: 10.1016/j.softx.2019.100395
external_id:
arxiv:
- '1908.00587'
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- '000552271200011'
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file_name: 2020_SoftwareX_Lopez.pdf
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intvolume: ' 11'
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language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '01'
oa: 1
oa_version: Published Version
publication: SoftwareX
publication_identifier:
eissn:
- '23527110'
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: nsCouette – A high-performance code for direct numerical simulations of turbulent
Taylor–Couette flow
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
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short: CC BY-NC-ND (4.0)
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...