---
_id: '9999'
abstract:
- lang: eng
  text: 'The developmental strategies used by progenitor cells to endure a safe journey
    from their induction place towards the site of terminal differentiation are still
    poorly understood. Here we uncovered a progenitor cell allocation mechanism that
    stems from an incomplete process of epithelial delamination that allows progenitors
    to coordinate their movement with adjacent extra-embryonic tissues. Progenitors
    of the zebrafish laterality organ originate from the surface epithelial enveloping
    layer by an apical constriction process of cell delamination. During this process,
    progenitors retain long-term apical contacts that enable the epithelial layer
    to pull a subset of progenitors along their way towards the vegetal pole. The
    remaining delaminated progenitors follow apically-attached progenitors’ movement
    by a co-attraction mechanism, avoiding sequestration by the adjacent endoderm,
    ensuring their fate and collective allocation at the differentiation site. Thus,
    we reveal that incomplete delamination serves as a cellular platform for coordinated
    tissue movements during development. Impact Statement: Incomplete delamination
    serves as a cellular platform for coordinated tissue movements during development,
    guiding newly formed progenitor cell groups to the differentiation site.'
article_number: e66483
article_processing_charge: Yes
article_type: original
author:
- first_name: Eduardo
  full_name: Pulgar, Eduardo
  last_name: Pulgar
- first_name: Cornelia
  full_name: Schwayer, Cornelia
  id: 3436488C-F248-11E8-B48F-1D18A9856A87
  last_name: Schwayer
  orcid: 0000-0001-5130-2226
- first_name: Néstor
  full_name: Guerrero, Néstor
  last_name: Guerrero
- first_name: Loreto
  full_name: López, Loreto
  last_name: López
- first_name: Susana
  full_name: Márquez, Susana
  last_name: Márquez
- first_name: Steffen
  full_name: Härtel, Steffen
  last_name: Härtel
- first_name: Rodrigo
  full_name: Soto, Rodrigo
  last_name: Soto
- first_name: Carl Philipp
  full_name: Heisenberg, Carl Philipp
  last_name: Heisenberg
- first_name: Miguel L.
  full_name: Concha, Miguel L.
  last_name: Concha
citation:
  ama: Pulgar E, Schwayer C, Guerrero N, et al. Apical contacts stemming from incomplete
    delamination guide progenitor cell allocation through a dragging mechanism. <i>eLife</i>.
    2021;10. doi:<a href="https://doi.org/10.7554/eLife.66483">10.7554/eLife.66483</a>
  apa: Pulgar, E., Schwayer, C., Guerrero, N., López, L., Márquez, S., Härtel, S.,
    … Concha, M. L. (2021). Apical contacts stemming from incomplete delamination
    guide progenitor cell allocation through a dragging mechanism. <i>ELife</i>. eLife
    Sciences Publications. <a href="https://doi.org/10.7554/eLife.66483">https://doi.org/10.7554/eLife.66483</a>
  chicago: Pulgar, Eduardo, Cornelia Schwayer, Néstor Guerrero, Loreto López, Susana
    Márquez, Steffen Härtel, Rodrigo Soto, Carl Philipp Heisenberg, and Miguel L.
    Concha. “Apical Contacts Stemming from Incomplete Delamination Guide Progenitor
    Cell Allocation through a Dragging Mechanism.” <i>ELife</i>. eLife Sciences Publications,
    2021. <a href="https://doi.org/10.7554/eLife.66483">https://doi.org/10.7554/eLife.66483</a>.
  ieee: E. Pulgar <i>et al.</i>, “Apical contacts stemming from incomplete delamination
    guide progenitor cell allocation through a dragging mechanism,” <i>eLife</i>,
    vol. 10. eLife Sciences Publications, 2021.
  ista: Pulgar E, Schwayer C, Guerrero N, López L, Márquez S, Härtel S, Soto R, Heisenberg
    CP, Concha ML. 2021. Apical contacts stemming from incomplete delamination guide
    progenitor cell allocation through a dragging mechanism. eLife. 10, e66483.
  mla: Pulgar, Eduardo, et al. “Apical Contacts Stemming from Incomplete Delamination
    Guide Progenitor Cell Allocation through a Dragging Mechanism.” <i>ELife</i>,
    vol. 10, e66483, eLife Sciences Publications, 2021, doi:<a href="https://doi.org/10.7554/eLife.66483">10.7554/eLife.66483</a>.
  short: E. Pulgar, C. Schwayer, N. Guerrero, L. López, S. Márquez, S. Härtel, R.
    Soto, C.P. Heisenberg, M.L. Concha, ELife 10 (2021).
date_created: 2021-09-12T22:01:23Z
date_published: 2021-08-27T00:00:00Z
date_updated: 2023-08-14T06:53:33Z
day: '27'
ddc:
- '570'
department:
- _id: CaHe
doi: 10.7554/eLife.66483
ec_funded: 1
external_id:
  isi:
  - '000700428500001'
  pmid:
  - '34448451'
file:
- access_level: open_access
  checksum: a3f82b0499cc822ac1eab48a01f3f57e
  content_type: application/pdf
  creator: dernst
  date_created: 2022-05-13T08:03:37Z
  date_updated: 2022-05-13T08:03:37Z
  file_id: '11371'
  file_name: 2021_eLife_Pulgar.pdf
  file_size: 9010446
  relation: main_file
  success: 1
file_date_updated: 2022-05-13T08:03:37Z
has_accepted_license: '1'
intvolume: '        10'
isi: 1
keyword:
- cell delamination
- apical constriction
- dragging
- mechanical forces
- collective 18 locomotion
- dorsal forerunner cells
- zebrafish
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '08'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 260F1432-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '742573'
  name: Interaction and feedback between cell mechanics and fate specification in
    vertebrate gastrulation
publication: eLife
publication_identifier:
  eissn:
  - 2050-084X
publication_status: published
publisher: eLife Sciences Publications
quality_controlled: '1'
scopus_import: '1'
status: public
title: Apical contacts stemming from incomplete delamination guide progenitor cell
  allocation through a dragging mechanism
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 10
year: '2021'
...
---
_id: '10672'
abstract:
- lang: eng
  text: The family of feedback alignment (FA) algorithms aims to provide a more biologically
    motivated alternative to backpropagation (BP), by substituting the computations
    that are unrealistic to be implemented in physical brains. While FA algorithms
    have been shown to work well in practice, there is a lack of rigorous theory proofing
    their learning capabilities. Here we introduce the first feedback alignment algorithm
    with provable learning guarantees. In contrast to existing work, we do not require
    any assumption about the size or depth of the network except that it has a single
    output neuron, i.e., such as for binary classification tasks. We show that our
    FA algorithm can deliver its theoretical promises in practice, surpassing the
    learning performance of existing FA methods and matching backpropagation in binary
    classification tasks. Finally, we demonstrate the limits of our FA variant when
    the number of output neurons grows beyond a certain quantity.
acknowledgement: "This research was supported in part by the Austrian Science Fund
  (FWF) under grant Z211-N23\r\n(Wittgenstein Award).\r\n"
article_processing_charge: No
author:
- first_name: Mathias
  full_name: Lechner, Mathias
  id: 3DC22916-F248-11E8-B48F-1D18A9856A87
  last_name: Lechner
citation:
  ama: 'Lechner M. Learning representations for binary-classification without backpropagation.
    In: <i>8th International Conference on Learning Representations</i>. ICLR; 2020.'
  apa: 'Lechner, M. (2020). Learning representations for binary-classification without
    backpropagation. In <i>8th International Conference on Learning Representations</i>.
    Virtual ; Addis Ababa, Ethiopia: ICLR.'
  chicago: Lechner, Mathias. “Learning Representations for Binary-Classification without
    Backpropagation.” In <i>8th International Conference on Learning Representations</i>.
    ICLR, 2020.
  ieee: M. Lechner, “Learning representations for binary-classification without backpropagation,”
    in <i>8th International Conference on Learning Representations</i>, Virtual ;
    Addis Ababa, Ethiopia, 2020.
  ista: 'Lechner M. 2020. Learning representations for binary-classification without
    backpropagation. 8th International Conference on Learning Representations. ICLR:
    International Conference on Learning Representations.'
  mla: Lechner, Mathias. “Learning Representations for Binary-Classification without
    Backpropagation.” <i>8th International Conference on Learning Representations</i>,
    ICLR, 2020.
  short: M. Lechner, in:, 8th International Conference on Learning Representations,
    ICLR, 2020.
conference:
  end_date: 2020-05-01
  location: Virtual ; Addis Ababa, Ethiopia
  name: 'ICLR: International Conference on Learning Representations'
  start_date: 2020-04-26
date_created: 2022-01-25T15:50:00Z
date_published: 2020-03-11T00:00:00Z
date_updated: 2023-04-03T07:33:40Z
day: '11'
ddc:
- '000'
department:
- _id: GradSch
- _id: ToHe
file:
- access_level: open_access
  checksum: ea13d42dd4541ddb239b6a75821fd6c9
  content_type: application/pdf
  creator: mlechner
  date_created: 2022-01-26T07:35:17Z
  date_updated: 2022-01-26T07:35:17Z
  file_id: '10677'
  file_name: iclr_2020.pdf
  file_size: 249431
  relation: main_file
  success: 1
file_date_updated: 2022-01-26T07:35:17Z
has_accepted_license: '1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/3.0/
main_file_link:
- open_access: '1'
  url: https://openreview.net/forum?id=Bke61krFvS
month: '03'
oa: 1
oa_version: Published Version
project:
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: Z211
  name: The Wittgenstein Prize
publication: 8th International Conference on Learning Representations
publication_status: published
publisher: ICLR
quality_controlled: '1'
scopus_import: '1'
status: public
title: Learning representations for binary-classification without backpropagation
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/3.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported (CC BY-NC-ND
    3.0)
  short: CC BY-NC-ND (3.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2020'
...
---
_id: '10673'
abstract:
- lang: eng
  text: We propose a neural information processing system obtained by re-purposing
    the function of a biological neural circuit model to govern simulated and real-world
    control tasks. Inspired by the structure of the nervous system of the soil-worm,
    C. elegans, we introduce ordinary neural circuits (ONCs), defined as the model
    of biological neural circuits reparameterized for the control of alternative tasks.
    We first demonstrate that ONCs realize networks with higher maximum flow compared
    to arbitrary wired networks. We then learn instances of ONCs to control a series
    of robotic tasks, including the autonomous parking of a real-world rover robot.
    For reconfiguration of the purpose of the neural circuit, we adopt a search-based
    optimization algorithm. Ordinary neural circuits perform on par and, in some cases,
    significantly surpass the performance of contemporary deep learning models. ONC
    networks are compact, 77% sparser than their counterpart neural controllers, and
    their neural dynamics are fully interpretable at the cell-level.
acknowledgement: "RH and RG are partially supported by Horizon-2020 ECSEL Project
  grant No. 783163 (iDev40), Productive 4.0, and ATBMBFW CPS-IoT Ecosystem. ML was
  supported in part by the Austrian Science Fund (FWF) under grant Z211-N23\r\n(Wittgenstein
  Award). AA is supported by the National Science Foundation (NSF) Graduate Research
  Fellowship\r\nProgram. RH and DR are partially supported by The Boeing Company and
  JP Morgan Chase. This research work is\r\npartially drawn from the PhD dissertation
  of RH.\r\n"
alternative_title:
- PMLR
article_processing_charge: No
author:
- first_name: Ramin
  full_name: Hasani, Ramin
  last_name: Hasani
- first_name: Mathias
  full_name: Lechner, Mathias
  id: 3DC22916-F248-11E8-B48F-1D18A9856A87
  last_name: Lechner
- first_name: Alexander
  full_name: Amini, Alexander
  last_name: Amini
- first_name: Daniela
  full_name: Rus, Daniela
  last_name: Rus
- first_name: Radu
  full_name: Grosu, Radu
  last_name: Grosu
citation:
  ama: 'Hasani R, Lechner M, Amini A, Rus D, Grosu R. A natural lottery ticket winner:
    Reinforcement learning with ordinary neural circuits. In: <i>Proceedings of the
    37th International Conference on Machine Learning</i>. PMLR. ; 2020:4082-4093.'
  apa: 'Hasani, R., Lechner, M., Amini, A., Rus, D., &#38; Grosu, R. (2020). A natural
    lottery ticket winner: Reinforcement learning with ordinary neural circuits. In
    <i>Proceedings of the 37th International Conference on Machine Learning</i> (pp.
    4082–4093). Virtual.'
  chicago: 'Hasani, Ramin, Mathias Lechner, Alexander Amini, Daniela Rus, and Radu
    Grosu. “A Natural Lottery Ticket Winner: Reinforcement Learning with Ordinary
    Neural Circuits.” In <i>Proceedings of the 37th International Conference on Machine
    Learning</i>, 4082–93. PMLR, 2020.'
  ieee: 'R. Hasani, M. Lechner, A. Amini, D. Rus, and R. Grosu, “A natural lottery
    ticket winner: Reinforcement learning with ordinary neural circuits,” in <i>Proceedings
    of the 37th International Conference on Machine Learning</i>, Virtual, 2020, pp.
    4082–4093.'
  ista: 'Hasani R, Lechner M, Amini A, Rus D, Grosu R. 2020. A natural lottery ticket
    winner: Reinforcement learning with ordinary neural circuits. Proceedings of the
    37th International Conference on Machine Learning. ML: Machine LearningPMLR, PMLR,
    , 4082–4093.'
  mla: 'Hasani, Ramin, et al. “A Natural Lottery Ticket Winner: Reinforcement Learning
    with Ordinary Neural Circuits.” <i>Proceedings of the 37th International Conference
    on Machine Learning</i>, 2020, pp. 4082–93.'
  short: R. Hasani, M. Lechner, A. Amini, D. Rus, R. Grosu, in:, Proceedings of the
    37th International Conference on Machine Learning, 2020, pp. 4082–4093.
conference:
  end_date: 2020-07-18
  location: Virtual
  name: 'ML: Machine Learning'
  start_date: 2020-07-12
date_created: 2022-01-25T15:50:34Z
date_published: 2020-01-01T00:00:00Z
date_updated: 2022-01-26T11:14:27Z
ddc:
- '000'
department:
- _id: GradSch
- _id: ToHe
file:
- access_level: open_access
  checksum: c9a4a29161777fc1a89ef451c040e3b1
  content_type: application/pdf
  creator: cchlebak
  date_created: 2022-01-26T11:08:51Z
  date_updated: 2022-01-26T11:08:51Z
  file_id: '10691'
  file_name: 2020_PMLR_Hasani.pdf
  file_size: 2329798
  relation: main_file
  success: 1
file_date_updated: 2022-01-26T11:08:51Z
has_accepted_license: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://proceedings.mlr.press/v119/hasani20a.html
oa: 1
oa_version: Published Version
page: 4082-4093
project:
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: Z211
  name: The Wittgenstein Prize
publication: Proceedings of the 37th International Conference on Machine Learning
publication_identifier:
  issn:
  - 2640-3498
publication_status: published
quality_controlled: '1'
scopus_import: '1'
series_title: PMLR
status: public
title: 'A natural lottery ticket winner: Reinforcement learning with ordinary neural
  circuits'
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/3.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported (CC BY-NC-ND
    3.0)
  short: CC BY-NC-ND (3.0)
type: conference
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2020'
...
---
_id: '10693'
abstract:
- lang: eng
  text: High quality graphene heterostructures host an array of fractional quantum
    Hall isospin ferromagnets with diverse spin and valley orders. While a variety
    of phase transitions have been observed, disentangling the isospin phase diagram
    of these states is hampered by the absence of direct probes of spin and valley
    order. I will describe nonlocal transport measurements based on launching spin
    waves from a gate defined lateral heterojunction, performed in ultra-clean Corbino
    geometry graphene devices. At high magnetic fields, we find that the spin-wave
    transport signal is detected in all FQH states between ν = 0 and 1; however, between
    ν = 1 and 2 only odd numerator FQH states show finite nonlocal transport, despite
    the identical ground state spin polarizations in odd- and even numerator states.
    The results reveal that the neutral spin-waves are both spin and sublattice polarized
    making them a sensitive probe of ground state sublattice structure. Armed with
    this understanding, we use nonlocal transport signal to a magnetic field tuned
    isospin phase transition, showing that the emergent even denominator state at
    ν = 1/2 in monolayer graphene is indeed a multicomponent state featuring equal
    populations on each sublattice.
alternative_title:
- Bulletin of the American Physical Society
article_number: B54. 00007
article_processing_charge: No
author:
- first_name: Haoxin
  full_name: Zhou, Haoxin
  last_name: Zhou
- first_name: Hryhoriy
  full_name: Polshyn, Hryhoriy
  id: edfc7cb1-526e-11ec-b05a-e6ecc27e4e48
  last_name: Polshyn
  orcid: 0000-0001-8223-8896
- first_name: Takashi
  full_name: Tanaguchi, Takashi
  last_name: Tanaguchi
- first_name: Kenji
  full_name: Watanabe, Kenji
  last_name: Watanabe
- first_name: Andrea
  full_name: Young, Andrea
  last_name: Young
citation:
  ama: 'Zhou H, Polshyn H, Tanaguchi T, Watanabe K, Young A. Sublattice resolved spin
    wave transport through graphene fractional quantum Hall states as a probe of isospin
    order. In: <i>APS March Meeting 2020</i>. Vol 65. American Physical Society; 2020.'
  apa: 'Zhou, H., Polshyn, H., Tanaguchi, T., Watanabe, K., &#38; Young, A. (2020).
    Sublattice resolved spin wave transport through graphene fractional quantum Hall
    states as a probe of isospin order. In <i>APS March Meeting 2020</i> (Vol. 65).
    Denver, CO, United States: American Physical Society.'
  chicago: Zhou, Haoxin, Hryhoriy Polshyn, Takashi Tanaguchi, Kenji Watanabe, and
    Andrea Young. “Sublattice Resolved Spin Wave Transport through Graphene Fractional
    Quantum Hall States as a Probe of Isospin Order.” In <i>APS March Meeting 2020</i>,
    Vol. 65. American Physical Society, 2020.
  ieee: H. Zhou, H. Polshyn, T. Tanaguchi, K. Watanabe, and A. Young, “Sublattice
    resolved spin wave transport through graphene fractional quantum Hall states as
    a probe of isospin order,” in <i>APS March Meeting 2020</i>, Denver, CO, United
    States, 2020, vol. 65, no. 1.
  ista: 'Zhou H, Polshyn H, Tanaguchi T, Watanabe K, Young A. 2020. Sublattice resolved
    spin wave transport through graphene fractional quantum Hall states as a probe
    of isospin order. APS March Meeting 2020. APS: American Physical Society, Bulletin
    of the American Physical Society, vol. 65, B54. 00007.'
  mla: Zhou, Haoxin, et al. “Sublattice Resolved Spin Wave Transport through Graphene
    Fractional Quantum Hall States as a Probe of Isospin Order.” <i>APS March Meeting
    2020</i>, vol. 65, no. 1, B54. 00007, American Physical Society, 2020.
  short: H. Zhou, H. Polshyn, T. Tanaguchi, K. Watanabe, A. Young, in:, APS March
    Meeting 2020, American Physical Society, 2020.
conference:
  end_date: 2020-03-06
  location: Denver, CO, United States
  name: 'APS: American Physical Society'
  start_date: 2020-03-02
date_created: 2022-01-27T10:50:10Z
date_published: 2020-03-01T00:00:00Z
date_updated: 2022-01-27T10:58:38Z
day: '01'
extern: '1'
intvolume: '        65'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://meetings.aps.org/Meeting/MAR20/Session/B54.7
month: '03'
oa: 1
oa_version: Published Version
publication: APS March Meeting 2020
publication_identifier:
  issn:
  - 0003-0503
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
status: public
title: Sublattice resolved spin wave transport through graphene fractional quantum
  Hall states as a probe of isospin order
type: conference
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 65
year: '2020'
...
---
_id: '10696'
abstract:
- lang: eng
  text: We experimentally investigate twisted van der Waals heterostructures of monolayer
    graphene rotated with respect to a bernal stacked graphene bilayer. We report
    transport measurements for devices with twist angles between 0.9 and 1.4°. The
    electric field allows efficient tuning of the width, isolation and the topology
    of the moiré bands in this system. By comparing magnetoresistance measurements
    to numerical simulations, we develop an understanding of the band structure. Finally,
    we observe correlated states at half- and quarter-fillings, which arise when narrow
    moire sublattice band is isolated by energy gaps from dispersive bands. We investigate
    the effects of in-plane and out-of-plane magnetic field on these states and discuss
    the implication for their spin- and valley- polarization.
alternative_title:
- Bulletin of the American Physical Society
article_number: B51.00005
article_processing_charge: No
author:
- first_name: Hryhoriy
  full_name: Polshyn, Hryhoriy
  id: edfc7cb1-526e-11ec-b05a-e6ecc27e4e48
  last_name: Polshyn
  orcid: 0000-0001-8223-8896
- first_name: Jihang
  full_name: Zhu, Jihang
  last_name: Zhu
- first_name: Manish
  full_name: Kumar, Manish
  last_name: Kumar
- first_name: Takashi
  full_name: Taniguchi, Takashi
  last_name: Taniguchi
- first_name: Kenji
  full_name: Watanabe, Kenji
  last_name: Watanabe
- first_name: Allan
  full_name: MacDonald, Allan
  last_name: MacDonald
- first_name: Andrea
  full_name: Young, Andrea
  last_name: Young
citation:
  ama: 'Polshyn H, Zhu J, Kumar M, et al. Correlated states and tunable topological
    bands in twisted monolayer-bilayer graphene heterostructures. In: <i>APS March
    Meeting 2020</i>. Vol 65. American Physical Society; 2020.'
  apa: 'Polshyn, H., Zhu, J., Kumar, M., Taniguchi, T., Watanabe, K., MacDonald, A.,
    &#38; Young, A. (2020). Correlated states and tunable topological bands in twisted
    monolayer-bilayer graphene heterostructures. In <i>APS March Meeting 2020</i>
    (Vol. 65). Denver, CO, United States: American Physical Society.'
  chicago: Polshyn, Hryhoriy, Jihang Zhu, Manish Kumar, Takashi Taniguchi, Kenji Watanabe,
    Allan MacDonald, and Andrea Young. “Correlated States and Tunable Topological
    Bands in Twisted Monolayer-Bilayer Graphene Heterostructures.” In <i>APS March
    Meeting 2020</i>, Vol. 65. American Physical Society, 2020.
  ieee: H. Polshyn <i>et al.</i>, “Correlated states and tunable topological bands
    in twisted monolayer-bilayer graphene heterostructures,” in <i>APS March Meeting
    2020</i>, Denver, CO, United States, 2020, vol. 65, no. 1.
  ista: 'Polshyn H, Zhu J, Kumar M, Taniguchi T, Watanabe K, MacDonald A, Young A.
    2020. Correlated states and tunable topological bands in twisted monolayer-bilayer
    graphene heterostructures. APS March Meeting 2020. APS: American Physical Society,
    Bulletin of the American Physical Society, vol. 65, B51.00005.'
  mla: Polshyn, Hryhoriy, et al. “Correlated States and Tunable Topological Bands
    in Twisted Monolayer-Bilayer Graphene Heterostructures.” <i>APS March Meeting
    2020</i>, vol. 65, no. 1, B51.00005, American Physical Society, 2020.
  short: H. Polshyn, J. Zhu, M. Kumar, T. Taniguchi, K. Watanabe, A. MacDonald, A.
    Young, in:, APS March Meeting 2020, American Physical Society, 2020.
conference:
  end_date: 2020-03-06
  location: Denver, CO, United States
  name: 'APS: American Physical Society'
  start_date: 2020-03-02
date_created: 2022-01-28T10:09:19Z
date_published: 2020-03-01T00:00:00Z
date_updated: 2022-02-08T10:22:08Z
day: '01'
extern: '1'
intvolume: '        65'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://meetings.aps.org/Meeting/MAR20/Session/B51.5
month: '03'
oa: 1
oa_version: Published Version
publication: APS March Meeting 2020
publication_identifier:
  issn:
  - 0003-0503
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
status: public
title: Correlated states and tunable topological bands in twisted monolayer-bilayer
  graphene heterostructures
type: conference
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 65
year: '2020'
...
---
_id: '10697'
abstract:
- lang: eng
  text: We report the observation of a quantized anomalous Hall effect in a moiré
    heterostructure consisting of twisted bilayer graphene aligned to an encapsulating
    hBN substrate. The effect occurs at a density of 3 electrons per superlattice
    unit cell, where we observe magnetic hysteresis and a Hall resistance quantized
    to within 0.1% of the resistance quantum at temperatures as high as 3K. In this
    first of 3 talks, I will describe the fabrication procedure for our device as
    well as basic transport characterization measurements. I will introduce the phenomenology
    of twisted bilayer graphene and present evidence for hBN alignment as manifested
    in the hierarchy of symmetry-breaking gaps and anomalous magnetoresistance.
acknowledgement: I would like to thank the MURI program, Sloan foundation, AFOSR,
  and ARO for their generous support of this work.
alternative_title:
- Bulletin of the American Physical Society
article_number: B59.00012
article_processing_charge: No
arxiv: 1
author:
- first_name: Yuxuan
  full_name: Zhang, Yuxuan
  last_name: Zhang
- first_name: Marec
  full_name: Serlin, Marec
  last_name: Serlin
- first_name: Charles
  full_name: Tschirhart, Charles
  last_name: Tschirhart
- first_name: Hryhoriy
  full_name: Polshyn, Hryhoriy
  id: edfc7cb1-526e-11ec-b05a-e6ecc27e4e48
  last_name: Polshyn
  orcid: 0000-0001-8223-8896
- first_name: Jiacheng
  full_name: Zhu, Jiacheng
  last_name: Zhu
- first_name: Leon
  full_name: Balents, Leon
  last_name: Balents
- first_name: Martin E.
  full_name: Huber, Martin E.
  last_name: Huber
- first_name: Takashi
  full_name: Taniguchi, Takashi
  last_name: Taniguchi
- first_name: Kenji
  full_name: Watanabe, Kenji
  last_name: Watanabe
- first_name: Andrea
  full_name: Young, Andrea
  last_name: Young
citation:
  ama: 'Zhang Y, Serlin M, Tschirhart C, et al. Intrinsic quantized anomalous Hall
    effect in a moiré heterostructure, part I: Device fabrication and transport. In:
    <i>APS March Meeting 2020</i>. Vol 65. American Physical Society; 2020.'
  apa: 'Zhang, Y., Serlin, M., Tschirhart, C., Polshyn, H., Zhu, J., Balents, L.,
    … Young, A. (2020). Intrinsic quantized anomalous Hall effect in a moiré heterostructure,
    part I: Device fabrication and transport. In <i>APS March Meeting 2020</i> (Vol.
    65). Denver, CO, United States: American Physical Society.'
  chicago: 'Zhang, Yuxuan, Marec Serlin, Charles Tschirhart, Hryhoriy Polshyn, Jiacheng
    Zhu, Leon Balents, Martin E. Huber, Takashi Taniguchi, Kenji Watanabe, and Andrea
    Young. “Intrinsic Quantized Anomalous Hall Effect in a Moiré Heterostructure,
    Part I: Device Fabrication and Transport.” In <i>APS March Meeting 2020</i>, Vol.
    65. American Physical Society, 2020.'
  ieee: 'Y. Zhang <i>et al.</i>, “Intrinsic quantized anomalous Hall effect in a moiré
    heterostructure, part I: Device fabrication and transport,” in <i>APS March Meeting
    2020</i>, Denver, CO, United States, 2020, vol. 65, no. 1.'
  ista: 'Zhang Y, Serlin M, Tschirhart C, Polshyn H, Zhu J, Balents L, Huber ME, Taniguchi
    T, Watanabe K, Young A. 2020. Intrinsic quantized anomalous Hall effect in a moiré
    heterostructure, part I: Device fabrication and transport. APS March Meeting 2020.
    APS: American Physical Society, Bulletin of the American Physical Society, vol.
    65, B59.00012.'
  mla: 'Zhang, Yuxuan, et al. “Intrinsic Quantized Anomalous Hall Effect in a Moiré
    Heterostructure, Part I: Device Fabrication and Transport.” <i>APS March Meeting
    2020</i>, vol. 65, no. 1, B59.00012, American Physical Society, 2020.'
  short: Y. Zhang, M. Serlin, C. Tschirhart, H. Polshyn, J. Zhu, L. Balents, M.E.
    Huber, T. Taniguchi, K. Watanabe, A. Young, in:, APS March Meeting 2020, American
    Physical Society, 2020.
conference:
  end_date: 2020-03-06
  location: Denver, CO, United States
  name: 'APS: American Physical Society'
  start_date: 2020-03-02
date_created: 2022-01-28T10:28:35Z
date_published: 2020-03-01T00:00:00Z
date_updated: 2023-02-21T15:57:52Z
day: '01'
extern: '1'
external_id:
  arxiv:
  - '1907.00261'
intvolume: '        65'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://meetings.aps.org/Meeting/MAR20/Session/B59.12
month: '03'
oa: 1
oa_version: Published Version
publication: APS March Meeting 2020
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
related_material:
  record:
  - id: '10619'
    relation: other
    status: public
status: public
title: 'Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part
  I: Device fabrication and transport'
type: conference
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 65
year: '2020'
...
---
_id: '10698'
abstract:
- lang: eng
  text: This is the second of three talks describing the observation and characterization
    of a ferromagnetic moiré heterostructure based on twisted bilayer graphene aligned
    to hexagonal boron nitride. I will compare the qualitative and quantitative features
    of this observed quantum anomalous Hall state to traditional systems engineered
    from thin film (Bi,Sb)2Te3 topological insulators. In particular, we find that
    the measured electronic energy gap of ~30K is several times higher than the Curie
    temperature, consistent with a lack of disorder associated with magnetic dopants.
    In this system, the quantization arises from spontaneous ferromagnetic polarization
    into a single spin and valley moiré subband, which is topological despite the
    lack of spin orbit coupling. I will also discuss the observation of current induced
    switching, which allows the magnetic state of the heterostructure to be controllably
    reversed with currents as small as a few nanoamperes.
acknowledgement: I would like to thank the MURI Program, AFOSR, Sloan Foundation,
  and the ARO for their generous support of this work.
alternative_title:
- Bulletin of the American Physical Society
article_number: B59.00011
article_processing_charge: No
arxiv: 1
author:
- first_name: Marec
  full_name: Serlin, Marec
  last_name: Serlin
- first_name: Charles
  full_name: Tschirhart, Charles
  last_name: Tschirhart
- first_name: Hryhoriy
  full_name: Polshyn, Hryhoriy
  id: edfc7cb1-526e-11ec-b05a-e6ecc27e4e48
  last_name: Polshyn
  orcid: 0000-0001-8223-8896
- first_name: Yuxuan
  full_name: Zhang, Yuxuan
  last_name: Zhang
- first_name: Jiacheng
  full_name: Zhu, Jiacheng
  last_name: Zhu
- first_name: Martin E.
  full_name: Huber, Martin E.
  last_name: Huber
- first_name: Leon
  full_name: Balents, Leon
  last_name: Balents
- first_name: Kenji
  full_name: Watanabe, Kenji
  last_name: Watanabe
- first_name: Takashi
  full_name: Tanaguchi, Takashi
  last_name: Tanaguchi
- first_name: Andrea
  full_name: Young, Andrea
  last_name: Young
citation:
  ama: 'Serlin M, Tschirhart C, Polshyn H, et al. Intrinsic quantized anomalous Hall
    effect in a moiré heterostructure, part II: Temperature dependence and current
    switching. In: <i>APS March Meeting 2020</i>. Vol 65. American Physical Society;
    2020.'
  apa: 'Serlin, M., Tschirhart, C., Polshyn, H., Zhang, Y., Zhu, J., Huber, M. E.,
    … Young, A. (2020). Intrinsic quantized anomalous Hall effect in a moiré heterostructure,
    part II: Temperature dependence and current switching. In <i>APS March Meeting
    2020</i> (Vol. 65). Denver, CO, United States: American Physical Society.'
  chicago: 'Serlin, Marec, Charles Tschirhart, Hryhoriy Polshyn, Yuxuan Zhang, Jiacheng
    Zhu, Martin E. Huber, Leon Balents, Kenji Watanabe, Takashi Tanaguchi, and Andrea
    Young. “Intrinsic Quantized Anomalous Hall Effect in a Moiré Heterostructure,
    Part II: Temperature Dependence and Current Switching.” In <i>APS March Meeting
    2020</i>, Vol. 65. American Physical Society, 2020.'
  ieee: 'M. Serlin <i>et al.</i>, “Intrinsic quantized anomalous Hall effect in a
    moiré heterostructure, part II: Temperature dependence and current switching,”
    in <i>APS March Meeting 2020</i>, Denver, CO, United States, 2020, vol. 65, no.
    1.'
  ista: 'Serlin M, Tschirhart C, Polshyn H, Zhang Y, Zhu J, Huber ME, Balents L, Watanabe
    K, Tanaguchi T, Young A. 2020. Intrinsic quantized anomalous Hall effect in a
    moiré heterostructure, part II: Temperature dependence and current switching.
    APS March Meeting 2020. APS: American Physical Society, Bulletin of the American
    Physical Society, vol. 65, B59.00011.'
  mla: 'Serlin, Marec, et al. “Intrinsic Quantized Anomalous Hall Effect in a Moiré
    Heterostructure, Part II: Temperature Dependence and Current Switching.” <i>APS
    March Meeting 2020</i>, vol. 65, no. 1, B59.00011, American Physical Society,
    2020.'
  short: M. Serlin, C. Tschirhart, H. Polshyn, Y. Zhang, J. Zhu, M.E. Huber, L. Balents,
    K. Watanabe, T. Tanaguchi, A. Young, in:, APS March Meeting 2020, American Physical
    Society, 2020.
conference:
  end_date: 2020-03-06
  location: Denver, CO, United States
  name: 'APS: American Physical Society'
  start_date: 2020-03-02
date_created: 2022-01-28T10:46:57Z
date_published: 2020-03-01T00:00:00Z
date_updated: 2023-02-21T15:57:52Z
day: '01'
extern: '1'
external_id:
  arxiv:
  - '1907.00261'
intvolume: '        65'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://meetings.aps.org/Meeting/MAR20/Session/B59.11
month: '03'
oa: 1
oa_version: Published Version
publication: APS March Meeting 2020
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
related_material:
  record:
  - id: '10619'
    relation: other
    status: public
status: public
title: 'Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part
  II: Temperature dependence and current switching'
type: conference
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 65
year: '2020'
...
---
_id: '10699'
abstract:
- lang: eng
  text: This is the third of three talks describing the observation and characterization
    of a ferromagnetic moiré heterostructure based on twisted bilayer graphene aligned
    to hexagonal boron nitride. In this segment I will present scanning probe magnetometry
    data acquired using a nanoSQUID-on-tip microscope, which provides ~150 nm spatial
    resolution and a field sensitivity of ~10 nT/rtHz. We study the distribution of
    magnetic domains within the device as a function of density, magnetic field training,
    and DC current. Our data allow us to constrain the magnitude of the orbital magnetic
    moment of the electrons in the QAH state. Comparison with simultaneously acquired
    transport data allows us to precisely correlate single domain dynamics with discrete
    jumps in the observed anomalous Hall signal.
acknowledgement: I would like to thank the MURI program, Sloan foundation, AFOSR,
  and ARO for their generous support of this work. I would also like to thank the
  NSF GRFP and the Hertz foundation for their generous support of my graduate studies.
alternative_title:
- Bulletin of the American Physical Society
article_number: B59.00013
article_processing_charge: No
arxiv: 1
author:
- first_name: Charles
  full_name: Tschirhart, Charles
  last_name: Tschirhart
- first_name: Marec
  full_name: Serlin, Marec
  last_name: Serlin
- first_name: Hryhoriy
  full_name: Polshyn, Hryhoriy
  id: edfc7cb1-526e-11ec-b05a-e6ecc27e4e48
  last_name: Polshyn
  orcid: 0000-0001-8223-8896
- first_name: Yuxuan
  full_name: Zhang, Yuxuan
  last_name: Zhang
- first_name: Jiacheng
  full_name: Zhu, Jiacheng
  last_name: Zhu
- first_name: Leon
  full_name: Balents, Leon
  last_name: Balents
- first_name: Martin E.
  full_name: Huber, Martin E.
  last_name: Huber
- first_name: Kenji
  full_name: Watanabe, Kenji
  last_name: Watanabe
- first_name: Takashi
  full_name: Tanaguchi, Takashi
  last_name: Tanaguchi
- first_name: Andrea
  full_name: Young, Andrea
  last_name: Young
citation:
  ama: 'Tschirhart C, Serlin M, Polshyn H, et al. Intrinsic quantized anomalous Hall
    effect in a moiré heterostructure, part III: Scanning probe magnetometry. In:
    <i>APS March Meeting 2020</i>. Vol 65. American Physical Society; 2020.'
  apa: 'Tschirhart, C., Serlin, M., Polshyn, H., Zhang, Y., Zhu, J., Balents, L.,
    … Young, A. (2020). Intrinsic quantized anomalous Hall effect in a moiré heterostructure,
    part III: Scanning probe magnetometry. In <i>APS March Meeting 2020</i> (Vol.
    65). Denver, CO, United States: American Physical Society.'
  chicago: 'Tschirhart, Charles, Marec Serlin, Hryhoriy Polshyn, Yuxuan Zhang, Jiacheng
    Zhu, Leon Balents, Martin E. Huber, Kenji Watanabe, Takashi Tanaguchi, and Andrea
    Young. “Intrinsic Quantized Anomalous Hall Effect in a Moiré Heterostructure,
    Part III: Scanning Probe Magnetometry.” In <i>APS March Meeting 2020</i>, Vol.
    65. American Physical Society, 2020.'
  ieee: 'C. Tschirhart <i>et al.</i>, “Intrinsic quantized anomalous Hall effect in
    a moiré heterostructure, part III: Scanning probe magnetometry,” in <i>APS March
    Meeting 2020</i>, Denver, CO, United States, 2020, vol. 65, no. 1.'
  ista: 'Tschirhart C, Serlin M, Polshyn H, Zhang Y, Zhu J, Balents L, Huber ME, Watanabe
    K, Tanaguchi T, Young A. 2020. Intrinsic quantized anomalous Hall effect in a
    moiré heterostructure, part III: Scanning probe magnetometry. APS March Meeting
    2020. APS: American Physical Society, Bulletin of the American Physical Society,
    vol. 65, B59.00013.'
  mla: 'Tschirhart, Charles, et al. “Intrinsic Quantized Anomalous Hall Effect in
    a Moiré Heterostructure, Part III: Scanning Probe Magnetometry.” <i>APS March
    Meeting 2020</i>, vol. 65, no. 1, B59.00013, American Physical Society, 2020.'
  short: C. Tschirhart, M. Serlin, H. Polshyn, Y. Zhang, J. Zhu, L. Balents, M.E.
    Huber, K. Watanabe, T. Tanaguchi, A. Young, in:, APS March Meeting 2020, American
    Physical Society, 2020.
conference:
  end_date: 2020-03-06
  location: Denver, CO, United States
  name: 'APS: American Physical Society'
  start_date: 2020-03-02
date_created: 2022-01-28T10:57:49Z
date_published: 2020-03-01T00:00:00Z
date_updated: 2023-02-21T15:57:52Z
day: '01'
extern: '1'
external_id:
  arxiv:
  - '1907.00261'
intvolume: '        65'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://meetings.aps.org/Meeting/MAR20/Session/B59.13
month: '03'
oa: 1
oa_version: Published Version
publication: APS March Meeting 2020
publication_identifier:
  issn:
  - 0003-0503
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
related_material:
  record:
  - id: '10619'
    relation: other
    status: public
status: public
title: 'Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part
  III: Scanning probe magnetometry'
type: conference
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 65
year: '2020'
...
---
_id: '10701'
abstract:
- lang: eng
  text: Partially filled Landau levels host competing electronic orders. For example,
    electron solids may prevail close to integer filling of the Landau levels before
    giving way to fractional quantum Hall liquids at higher carrier density1,2. Here,
    we report the observation of an electron solid with non-collinear spin texture
    in monolayer graphene, consistent with solidification of skyrmions3—topological
    spin textures characterized by quantized electrical charge4,5. We probe the spin
    texture of the solids using a modified Corbino geometry that allows ferromagnetic
    magnons to be launched and detected6,7. We find that magnon transport is highly
    efficient when one Landau level is filled (ν=1), consistent with quantum Hall
    ferromagnetic spin polarization. However, even minimal doping immediately quenches
    the magnon signal while leaving the vanishing low-temperature charge conductivity
    unchanged. Our results can be understood by the formation of a solid of charged
    skyrmions near ν=1, whose non-collinear spin texture leads to rapid magnon decay.
    Data near fractional fillings show evidence of several fractional skyrmion solids,
    suggesting that graphene hosts a highly tunable landscape of coupled spin and
    charge orders.
acknowledgement: We acknowledge discussions with B. Halperin, C. Huang, A. Macdonald
  and M. Zalatel. Experimental work at UCSB was supported by the Army Research Office
  under awards nos. MURI W911NF-16-1-0361 and W911NF-16-1-0482. K.W. and T.T. acknowledge
  support from the Elemental Strategy Initiative conducted by MEXT (Japan) and CREST
  (JPMJCR15F3), JST. A.F.Y. acknowledges the support of the David and Lucile Packard
  Foundation and and Alfred. P. Sloan Foundation.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Haoxin
  full_name: Zhou, Haoxin
  last_name: Zhou
- first_name: Hryhoriy
  full_name: Polshyn, Hryhoriy
  id: edfc7cb1-526e-11ec-b05a-e6ecc27e4e48
  last_name: Polshyn
  orcid: 0000-0001-8223-8896
- first_name: Takashi
  full_name: Taniguchi, Takashi
  last_name: Taniguchi
- first_name: Kenji
  full_name: Watanabe, Kenji
  last_name: Watanabe
- first_name: Andrea F.
  full_name: Young, Andrea F.
  last_name: Young
citation:
  ama: Zhou H, Polshyn H, Taniguchi T, Watanabe K, Young AF. Skyrmion solids in monolayer
    graphene. <i>Nature Physics</i>. 2020;16(2):154-158. doi:<a href="https://doi.org/10.1038/s41567-019-0729-8">10.1038/s41567-019-0729-8</a>
  apa: Zhou, H., Polshyn, H., Taniguchi, T., Watanabe, K., &#38; Young, A. F. (2020).
    Skyrmion solids in monolayer graphene. <i>Nature Physics</i>. Springer Nature.
    <a href="https://doi.org/10.1038/s41567-019-0729-8">https://doi.org/10.1038/s41567-019-0729-8</a>
  chicago: Zhou, Haoxin, Hryhoriy Polshyn, Takashi Taniguchi, Kenji Watanabe, and
    Andrea F. Young. “Skyrmion Solids in Monolayer Graphene.” <i>Nature Physics</i>.
    Springer Nature, 2020. <a href="https://doi.org/10.1038/s41567-019-0729-8">https://doi.org/10.1038/s41567-019-0729-8</a>.
  ieee: H. Zhou, H. Polshyn, T. Taniguchi, K. Watanabe, and A. F. Young, “Skyrmion
    solids in monolayer graphene,” <i>Nature Physics</i>, vol. 16, no. 2. Springer
    Nature, pp. 154–158, 2020.
  ista: Zhou H, Polshyn H, Taniguchi T, Watanabe K, Young AF. 2020. Skyrmion solids
    in monolayer graphene. Nature Physics. 16(2), 154–158.
  mla: Zhou, Haoxin, et al. “Skyrmion Solids in Monolayer Graphene.” <i>Nature Physics</i>,
    vol. 16, no. 2, Springer Nature, 2020, pp. 154–58, doi:<a href="https://doi.org/10.1038/s41567-019-0729-8">10.1038/s41567-019-0729-8</a>.
  short: H. Zhou, H. Polshyn, T. Taniguchi, K. Watanabe, A.F. Young, Nature Physics
    16 (2020) 154–158.
date_created: 2022-01-28T12:04:09Z
date_published: 2020-02-01T00:00:00Z
date_updated: 2022-01-31T07:10:07Z
day: '01'
doi: 10.1038/s41567-019-0729-8
extern: '1'
external_id:
  arxiv:
  - '1904.11485'
intvolume: '        16'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1904.11485
month: '02'
oa: 1
oa_version: Preprint
page: 154-158
publication: Nature Physics
publication_identifier:
  eissn:
  - 1745-2481
  issn:
  - 1745-2473
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Skyrmion solids in monolayer graphene
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 16
year: '2020'
...
---
_id: '10861'
abstract:
- lang: eng
  text: We introduce in this paper AMT2.0, a tool for qualitative and quantitative
    analysis of hybrid continuous and Boolean signals that combine numerical values
    and discrete events. The evaluation of the signals is based on rich temporal specifications
    expressed in extended signal temporal logic, which integrates timed regular expressions
    within signal temporal logic. The tool features qualitative monitoring (property
    satisfaction checking), trace diagnostics for explaining and justifying property
    violations and specification-driven measurement of quantitative features of the
    signal. We demonstrate the tool functionality on several running examples and
    case studies, and evaluate its performance.
article_processing_charge: No
article_type: original
author:
- first_name: Dejan
  full_name: Nickovic, Dejan
  id: 41BCEE5C-F248-11E8-B48F-1D18A9856A87
  last_name: Nickovic
- first_name: Olivier
  full_name: Lebeltel, Olivier
  last_name: Lebeltel
- first_name: Oded
  full_name: Maler, Oded
  last_name: Maler
- first_name: Thomas
  full_name: Ferrere, Thomas
  id: 40960E6E-F248-11E8-B48F-1D18A9856A87
  last_name: Ferrere
  orcid: 0000-0001-5199-3143
- first_name: Dogan
  full_name: Ulus, Dogan
  last_name: Ulus
citation:
  ama: 'Nickovic D, Lebeltel O, Maler O, Ferrere T, Ulus D. AMT 2.0: Qualitative and
    quantitative trace analysis with extended signal temporal logic. <i>International
    Journal on Software Tools for Technology Transfer</i>. 2020;22(6):741-758. doi:<a
    href="https://doi.org/10.1007/s10009-020-00582-z">10.1007/s10009-020-00582-z</a>'
  apa: 'Nickovic, D., Lebeltel, O., Maler, O., Ferrere, T., &#38; Ulus, D. (2020).
    AMT 2.0: Qualitative and quantitative trace analysis with extended signal temporal
    logic. <i>International Journal on Software Tools for Technology Transfer</i>.
    Springer Nature. <a href="https://doi.org/10.1007/s10009-020-00582-z">https://doi.org/10.1007/s10009-020-00582-z</a>'
  chicago: 'Nickovic, Dejan, Olivier Lebeltel, Oded Maler, Thomas Ferrere, and Dogan
    Ulus. “AMT 2.0: Qualitative and Quantitative Trace Analysis with Extended Signal
    Temporal Logic.” <i>International Journal on Software Tools for Technology Transfer</i>.
    Springer Nature, 2020. <a href="https://doi.org/10.1007/s10009-020-00582-z">https://doi.org/10.1007/s10009-020-00582-z</a>.'
  ieee: 'D. Nickovic, O. Lebeltel, O. Maler, T. Ferrere, and D. Ulus, “AMT 2.0: Qualitative
    and quantitative trace analysis with extended signal temporal logic,” <i>International
    Journal on Software Tools for Technology Transfer</i>, vol. 22, no. 6. Springer
    Nature, pp. 741–758, 2020.'
  ista: 'Nickovic D, Lebeltel O, Maler O, Ferrere T, Ulus D. 2020. AMT 2.0: Qualitative
    and quantitative trace analysis with extended signal temporal logic. International
    Journal on Software Tools for Technology Transfer. 22(6), 741–758.'
  mla: 'Nickovic, Dejan, et al. “AMT 2.0: Qualitative and Quantitative Trace Analysis
    with Extended Signal Temporal Logic.” <i>International Journal on Software Tools
    for Technology Transfer</i>, vol. 22, no. 6, Springer Nature, 2020, pp. 741–58,
    doi:<a href="https://doi.org/10.1007/s10009-020-00582-z">10.1007/s10009-020-00582-z</a>.'
  short: D. Nickovic, O. Lebeltel, O. Maler, T. Ferrere, D. Ulus, International Journal
    on Software Tools for Technology Transfer 22 (2020) 741–758.
date_created: 2022-03-18T10:10:53Z
date_published: 2020-08-03T00:00:00Z
date_updated: 2023-09-08T11:52:02Z
day: '03'
department:
- _id: ToHe
doi: 10.1007/s10009-020-00582-z
external_id:
  isi:
  - '000555398600001'
intvolume: '        22'
isi: 1
issue: '6'
keyword:
- Information Systems
- Software
language:
- iso: eng
month: '08'
oa_version: None
page: 741-758
publication: International Journal on Software Tools for Technology Transfer
publication_identifier:
  eissn:
  - 1433-2787
  issn:
  - 1433-2779
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  record:
  - id: '299'
    relation: earlier_version
    status: public
scopus_import: '1'
status: public
title: 'AMT 2.0: Qualitative and quantitative trace analysis with extended signal
  temporal logic'
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 22
year: '2020'
...
---
_id: '10862'
abstract:
- lang: eng
  text: We consider the sum of two large Hermitian matrices A and B with a Haar unitary
    conjugation bringing them into a general relative position. We prove that the
    eigenvalue density on the scale slightly above the local eigenvalue spacing is
    asymptotically given by the free additive convolution of the laws of A and B as
    the dimension of the matrix increases. This implies optimal rigidity of the eigenvalues
    and optimal rate of convergence in Voiculescu's theorem. Our previous works [4],
    [5] established these results in the bulk spectrum, the current paper completely
    settles the problem at the spectral edges provided they have the typical square-root
    behavior. The key element of our proof is to compensate the deterioration of the
    stability of the subordination equations by sharp error estimates that properly
    account for the local density near the edge. Our results also hold if the Haar
    unitary matrix is replaced by the Haar orthogonal matrix.
acknowledgement: Partially supported by ERC Advanced Grant RANMAT No. 338804.
article_number: '108639'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Zhigang
  full_name: Bao, Zhigang
  id: 442E6A6C-F248-11E8-B48F-1D18A9856A87
  last_name: Bao
  orcid: 0000-0003-3036-1475
- first_name: László
  full_name: Erdös, László
  id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
  last_name: Erdös
  orcid: 0000-0001-5366-9603
- first_name: Kevin
  full_name: Schnelli, Kevin
  last_name: Schnelli
citation:
  ama: Bao Z, Erdös L, Schnelli K. Spectral rigidity for addition of random matrices
    at the regular edge. <i>Journal of Functional Analysis</i>. 2020;279(7). doi:<a
    href="https://doi.org/10.1016/j.jfa.2020.108639">10.1016/j.jfa.2020.108639</a>
  apa: Bao, Z., Erdös, L., &#38; Schnelli, K. (2020). Spectral rigidity for addition
    of random matrices at the regular edge. <i>Journal of Functional Analysis</i>.
    Elsevier. <a href="https://doi.org/10.1016/j.jfa.2020.108639">https://doi.org/10.1016/j.jfa.2020.108639</a>
  chicago: Bao, Zhigang, László Erdös, and Kevin Schnelli. “Spectral Rigidity for
    Addition of Random Matrices at the Regular Edge.” <i>Journal of Functional Analysis</i>.
    Elsevier, 2020. <a href="https://doi.org/10.1016/j.jfa.2020.108639">https://doi.org/10.1016/j.jfa.2020.108639</a>.
  ieee: Z. Bao, L. Erdös, and K. Schnelli, “Spectral rigidity for addition of random
    matrices at the regular edge,” <i>Journal of Functional Analysis</i>, vol. 279,
    no. 7. Elsevier, 2020.
  ista: Bao Z, Erdös L, Schnelli K. 2020. Spectral rigidity for addition of random
    matrices at the regular edge. Journal of Functional Analysis. 279(7), 108639.
  mla: Bao, Zhigang, et al. “Spectral Rigidity for Addition of Random Matrices at
    the Regular Edge.” <i>Journal of Functional Analysis</i>, vol. 279, no. 7, 108639,
    Elsevier, 2020, doi:<a href="https://doi.org/10.1016/j.jfa.2020.108639">10.1016/j.jfa.2020.108639</a>.
  short: Z. Bao, L. Erdös, K. Schnelli, Journal of Functional Analysis 279 (2020).
date_created: 2022-03-18T10:18:59Z
date_published: 2020-10-15T00:00:00Z
date_updated: 2023-08-24T14:08:42Z
day: '15'
department:
- _id: LaEr
doi: 10.1016/j.jfa.2020.108639
ec_funded: 1
external_id:
  arxiv:
  - '1708.01597'
  isi:
  - '000559623200009'
intvolume: '       279'
isi: 1
issue: '7'
keyword:
- Analysis
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1708.01597
month: '10'
oa: 1
oa_version: Preprint
project:
- _id: 258DCDE6-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '338804'
  name: Random matrices, universality and disordered quantum systems
publication: Journal of Functional Analysis
publication_identifier:
  issn:
  - 0022-1236
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Spectral rigidity for addition of random matrices at the regular edge
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 279
year: '2020'
...
---
_id: '10865'
abstract:
- lang: eng
  text: "We introduce the notion of Witness Maps as a cryptographic notion of a proof
    system. A Unique Witness Map (UWM) deterministically maps all witnesses for an
    \  NP  statement to a single representative witness, resulting in a computationally
    sound, deterministic-prover, non-interactive witness independent proof system.
    A relaxation of UWM, called Compact Witness Map (CWM), maps all the witnesses
    to a small number of witnesses, resulting in a “lossy” deterministic-prover, non-interactive
    proof-system. We also define a Dual Mode Witness Map (DMWM) which adds an “extractable”
    mode to a CWM.\r\nOur main construction is a DMWM for all   NP  relations, assuming
    sub-exponentially secure indistinguishability obfuscation (  iO ), along with
    standard cryptographic assumptions. The DMWM construction relies on a CWM and
    a new primitive called Cumulative All-Lossy-But-One Trapdoor Functions (C-ALBO-TDF),
    both of which are in turn instantiated based on   iO  and other primitives. Our
    instantiation of a CWM is in fact a UWM; in turn, we show that a UWM implies Witness
    Encryption. Along the way to constructing UWM and C-ALBO-TDF, we also construct,
    from standard assumptions, Puncturable Digital Signatures and a new primitive
    called Cumulative Lossy Trapdoor Functions (C-LTDF). The former improves up on
    a construction of Bellare et al. (Eurocrypt 2016), who relied on sub-exponentially
    secure   iO  and sub-exponentially secure OWF.\r\nAs an application of our constructions,
    we show how to use a DMWM to construct the first leakage and tamper-resilient
    signatures with a deterministic signer, thereby solving a decade old open problem
    posed by Katz and Vaikunthanathan (Asiacrypt 2009), by Boyle, Segev and Wichs
    (Eurocrypt 2011), as well as by Faonio and Venturi (Asiacrypt 2016). Our construction
    achieves the optimal leakage rate of   1−o(1) ."
acknowledgement: We would like to thank the anonymous reviewers of PKC 2019 for their
  useful comments and suggestions. We thank Omer Paneth for pointing out to us the
  connection between Unique Witness Maps (UWM) and Witness encryption (WE). The first
  author would like to acknowledge Pandu Rangan for his involvement during the initial
  discussion phase of the project.
article_processing_charge: No
author:
- first_name: Suvradip
  full_name: Chakraborty, Suvradip
  id: B9CD0494-D033-11E9-B219-A439E6697425
  last_name: Chakraborty
- first_name: Manoj
  full_name: Prabhakaran, Manoj
  last_name: Prabhakaran
- first_name: Daniel
  full_name: Wichs, Daniel
  last_name: Wichs
citation:
  ama: 'Chakraborty S, Prabhakaran M, Wichs D. Witness maps and applications. In:
    Kiayias A, ed. <i>Public-Key Cryptography</i>. Vol 12110. LNCS. Cham: Springer
    Nature; 2020:220-246. doi:<a href="https://doi.org/10.1007/978-3-030-45374-9_8">10.1007/978-3-030-45374-9_8</a>'
  apa: 'Chakraborty, S., Prabhakaran, M., &#38; Wichs, D. (2020). Witness maps and
    applications. In A. Kiayias (Ed.), <i>Public-Key Cryptography</i> (Vol. 12110,
    pp. 220–246). Cham: Springer Nature. <a href="https://doi.org/10.1007/978-3-030-45374-9_8">https://doi.org/10.1007/978-3-030-45374-9_8</a>'
  chicago: 'Chakraborty, Suvradip, Manoj Prabhakaran, and Daniel Wichs. “Witness Maps
    and Applications.” In <i>Public-Key Cryptography</i>, edited by A Kiayias, 12110:220–46.
    LNCS. Cham: Springer Nature, 2020. <a href="https://doi.org/10.1007/978-3-030-45374-9_8">https://doi.org/10.1007/978-3-030-45374-9_8</a>.'
  ieee: 'S. Chakraborty, M. Prabhakaran, and D. Wichs, “Witness maps and applications,”
    in <i>Public-Key Cryptography</i>, vol. 12110, A. Kiayias, Ed. Cham: Springer
    Nature, 2020, pp. 220–246.'
  ista: 'Chakraborty S, Prabhakaran M, Wichs D. 2020.Witness maps and applications.
    In: Public-Key Cryptography. vol. 12110, 220–246.'
  mla: Chakraborty, Suvradip, et al. “Witness Maps and Applications.” <i>Public-Key
    Cryptography</i>, edited by A Kiayias, vol. 12110, Springer Nature, 2020, pp.
    220–46, doi:<a href="https://doi.org/10.1007/978-3-030-45374-9_8">10.1007/978-3-030-45374-9_8</a>.
  short: S. Chakraborty, M. Prabhakaran, D. Wichs, in:, A. Kiayias (Ed.), Public-Key
    Cryptography, Springer Nature, Cham, 2020, pp. 220–246.
date_created: 2022-03-18T11:35:51Z
date_published: 2020-04-29T00:00:00Z
date_updated: 2023-09-05T15:10:02Z
day: '29'
doi: 10.1007/978-3-030-45374-9_8
editor:
- first_name: A
  full_name: Kiayias, A
  last_name: Kiayias
intvolume: '     12110'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://eprint.iacr.org/2020/090
month: '04'
oa: 1
oa_version: Preprint
page: 220-246
place: Cham
publication: Public-Key Cryptography
publication_identifier:
  eissn:
  - 1611-3349
  isbn:
  - '9783030453732'
  - '9783030453749'
  issn:
  - 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
series_title: LNCS
status: public
title: Witness maps and applications
type: book_chapter
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 12110
year: '2020'
...
---
_id: '10866'
abstract:
- lang: eng
  text: Recent discoveries have shown that, when two layers of van der Waals (vdW)
    materials are superimposed with a relative twist angle between them, the electronic
    properties of the coupled system can be dramatically altered. Here, we demonstrate
    that a similar concept can be extended to the optics realm, particularly to propagating
    phonon polaritons–hybrid light-matter interactions. To do this, we fabricate stacks
    composed of two twisted slabs of a vdW crystal (α-MoO3) supporting anisotropic
    phonon polaritons (PhPs), and image the propagation of the latter when launched
    by localized sources. Our images reveal that, under a critical angle, the PhPs
    isofrequency curve undergoes a topological transition, in which the propagation
    of PhPs is strongly guided (canalization regime) along predetermined directions
    without geometric spreading. These results demonstrate a new degree of freedom
    (twist angle) for controlling the propagation of polaritons at the nanoscale with
    potential for nanoimaging, (bio)-sensing, or heat management.
acknowledgement: "J.T.-G. and G.Á.-P. acknowledge support through the Severo Ochoa
  Program from the\r\nGovernment of the Principality of Asturias (nos. PA-18-PF-BP17-126
  and PA20-PF-BP19-053,\r\nrespectively). J. M-S acknowledges financial support through
  the Ramón y Cajal Program from\r\nthe Government of Spain (RYC2018-026196-I). A.Y.N.
  acknowledges the Spanish Ministry of\r\nScience, Innovation and Universities (national
  project no. MAT201788358-C3-3-R). P.A.-G.\r\nacknowledges support from the European
  Research Council under starting grant no. 715496,\r\n2DNANOPTICA."
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Jiahua
  full_name: Duan, Jiahua
  last_name: Duan
- first_name: Nathaniel
  full_name: Capote-Robayna, Nathaniel
  last_name: Capote-Robayna
- first_name: Javier
  full_name: Taboada-Gutiérrez, Javier
  last_name: Taboada-Gutiérrez
- first_name: Gonzalo
  full_name: Álvarez-Pérez, Gonzalo
  last_name: Álvarez-Pérez
- first_name: Ivan
  full_name: Prieto Gonzalez, Ivan
  id: 2A307FE2-F248-11E8-B48F-1D18A9856A87
  last_name: Prieto Gonzalez
  orcid: 0000-0002-7370-5357
- first_name: Javier
  full_name: Martín-Sánchez, Javier
  last_name: Martín-Sánchez
- first_name: Alexey Y.
  full_name: Nikitin, Alexey Y.
  last_name: Nikitin
- first_name: Pablo
  full_name: Alonso-González, Pablo
  last_name: Alonso-González
citation:
  ama: 'Duan J, Capote-Robayna N, Taboada-Gutiérrez J, et al. Twisted nano-optics:
    Manipulating light at the nanoscale with twisted phonon polaritonic slabs. <i>Nano
    Letters</i>. 2020;20(7):5323-5329. doi:<a href="https://doi.org/10.1021/acs.nanolett.0c01673">10.1021/acs.nanolett.0c01673</a>'
  apa: 'Duan, J., Capote-Robayna, N., Taboada-Gutiérrez, J., Álvarez-Pérez, G., Prieto
    Gonzalez, I., Martín-Sánchez, J., … Alonso-González, P. (2020). Twisted nano-optics:
    Manipulating light at the nanoscale with twisted phonon polaritonic slabs. <i>Nano
    Letters</i>. American Chemical Society. <a href="https://doi.org/10.1021/acs.nanolett.0c01673">https://doi.org/10.1021/acs.nanolett.0c01673</a>'
  chicago: 'Duan, Jiahua, Nathaniel Capote-Robayna, Javier Taboada-Gutiérrez, Gonzalo
    Álvarez-Pérez, Ivan Prieto Gonzalez, Javier Martín-Sánchez, Alexey Y. Nikitin,
    and Pablo Alonso-González. “Twisted Nano-Optics: Manipulating Light at the Nanoscale
    with Twisted Phonon Polaritonic Slabs.” <i>Nano Letters</i>. American Chemical
    Society, 2020. <a href="https://doi.org/10.1021/acs.nanolett.0c01673">https://doi.org/10.1021/acs.nanolett.0c01673</a>.'
  ieee: 'J. Duan <i>et al.</i>, “Twisted nano-optics: Manipulating light at the nanoscale
    with twisted phonon polaritonic slabs,” <i>Nano Letters</i>, vol. 20, no. 7. American
    Chemical Society, pp. 5323–5329, 2020.'
  ista: 'Duan J, Capote-Robayna N, Taboada-Gutiérrez J, Álvarez-Pérez G, Prieto Gonzalez
    I, Martín-Sánchez J, Nikitin AY, Alonso-González P. 2020. Twisted nano-optics:
    Manipulating light at the nanoscale with twisted phonon polaritonic slabs. Nano
    Letters. 20(7), 5323–5329.'
  mla: 'Duan, Jiahua, et al. “Twisted Nano-Optics: Manipulating Light at the Nanoscale
    with Twisted Phonon Polaritonic Slabs.” <i>Nano Letters</i>, vol. 20, no. 7, American
    Chemical Society, 2020, pp. 5323–29, doi:<a href="https://doi.org/10.1021/acs.nanolett.0c01673">10.1021/acs.nanolett.0c01673</a>.'
  short: J. Duan, N. Capote-Robayna, J. Taboada-Gutiérrez, G. Álvarez-Pérez, I. Prieto
    Gonzalez, J. Martín-Sánchez, A.Y. Nikitin, P. Alonso-González, Nano Letters 20
    (2020) 5323–5329.
date_created: 2022-03-18T11:37:38Z
date_published: 2020-07-01T00:00:00Z
date_updated: 2023-09-05T12:05:58Z
day: '01'
department:
- _id: NanoFab
doi: 10.1021/acs.nanolett.0c01673
external_id:
  arxiv:
  - '2004.14599'
  isi:
  - '000548893200082'
  pmid:
  - '32530634'
intvolume: '        20'
isi: 1
issue: '7'
keyword:
- Mechanical Engineering
- Condensed Matter Physics
- General Materials Science
- General Chemistry
- Bioengineering
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2004.14599
month: '07'
oa: 1
oa_version: Preprint
page: 5323-5329
pmid: 1
publication: Nano Letters
publication_identifier:
  eissn:
  - 1530-6992
  issn:
  - 1530-6984
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Twisted nano-optics: Manipulating light at the nanoscale with twisted phonon
  polaritonic slabs'
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 20
year: '2020'
...
---
_id: '10867'
abstract:
- lang: eng
  text: In this paper we find a tight estimate for Gromov’s waist of the balls in
    spaces of constant curvature, deduce the estimates for the balls in Riemannian
    manifolds with upper bounds on the curvature (CAT(ϰ)-spaces), and establish similar
    result for normed spaces.
acknowledgement: ' Supported by the Russian Foundation for Basic Research grant 18-01-00036.'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Arseniy
  full_name: Akopyan, Arseniy
  id: 430D2C90-F248-11E8-B48F-1D18A9856A87
  last_name: Akopyan
  orcid: 0000-0002-2548-617X
- first_name: Roman
  full_name: Karasev, Roman
  last_name: Karasev
citation:
  ama: Akopyan A, Karasev R. Waist of balls in hyperbolic and spherical spaces. <i>International
    Mathematics Research Notices</i>. 2020;2020(3):669-697. doi:<a href="https://doi.org/10.1093/imrn/rny037">10.1093/imrn/rny037</a>
  apa: Akopyan, A., &#38; Karasev, R. (2020). Waist of balls in hyperbolic and spherical
    spaces. <i>International Mathematics Research Notices</i>. Oxford University Press.
    <a href="https://doi.org/10.1093/imrn/rny037">https://doi.org/10.1093/imrn/rny037</a>
  chicago: Akopyan, Arseniy, and Roman Karasev. “Waist of Balls in Hyperbolic and
    Spherical Spaces.” <i>International Mathematics Research Notices</i>. Oxford University
    Press, 2020. <a href="https://doi.org/10.1093/imrn/rny037">https://doi.org/10.1093/imrn/rny037</a>.
  ieee: A. Akopyan and R. Karasev, “Waist of balls in hyperbolic and spherical spaces,”
    <i>International Mathematics Research Notices</i>, vol. 2020, no. 3. Oxford University
    Press, pp. 669–697, 2020.
  ista: Akopyan A, Karasev R. 2020. Waist of balls in hyperbolic and spherical spaces.
    International Mathematics Research Notices. 2020(3), 669–697.
  mla: Akopyan, Arseniy, and Roman Karasev. “Waist of Balls in Hyperbolic and Spherical
    Spaces.” <i>International Mathematics Research Notices</i>, vol. 2020, no. 3,
    Oxford University Press, 2020, pp. 669–97, doi:<a href="https://doi.org/10.1093/imrn/rny037">10.1093/imrn/rny037</a>.
  short: A. Akopyan, R. Karasev, International Mathematics Research Notices 2020 (2020)
    669–697.
date_created: 2022-03-18T11:39:30Z
date_published: 2020-02-01T00:00:00Z
date_updated: 2023-08-24T14:19:55Z
day: '01'
department:
- _id: HeEd
doi: 10.1093/imrn/rny037
external_id:
  arxiv:
  - '1702.07513'
  isi:
  - '000522852700002'
intvolume: '      2020'
isi: 1
issue: '3'
keyword:
- General Mathematics
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1702.07513
month: '02'
oa: 1
oa_version: Preprint
page: 669-697
publication: International Mathematics Research Notices
publication_identifier:
  eissn:
  - 1687-0247
  issn:
  - 1073-7928
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Waist of balls in hyperbolic and spherical spaces
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 2020
year: '2020'
...
---
_id: '11054'
abstract:
- lang: eng
  text: In recent years, the nuclear pore complex (NPC) has emerged as a key player
    in genome regulation and cellular homeostasis. New discoveries have revealed that
    the NPC has multiple cellular functions besides mediating the molecular exchange
    between the nucleus and the cytoplasm. In this review, we discuss non-transport
    aspects of the NPC focusing on the NPC-genome interaction, the extreme longevity
    of the NPC proteins, and NPC dysfunction in age-related diseases. The examples
    summarized herein demonstrate that the NPC, which first evolved to enable the
    biochemical communication between the nucleus and the cytoplasm, now doubles as
    the gatekeeper of cellular identity and aging.
article_processing_charge: No
article_type: review
author:
- first_name: Ukrae H.
  full_name: Cho, Ukrae H.
  last_name: Cho
- first_name: Martin W
  full_name: HETZER, Martin W
  id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
  last_name: HETZER
  orcid: 0000-0002-2111-992X
citation:
  ama: 'Cho UH, Hetzer M. Nuclear periphery takes center stage: The role of nuclear
    pore complexes in cell identity and aging. <i>Neuron</i>. 2020;106(6):899-911.
    doi:<a href="https://doi.org/10.1016/j.neuron.2020.05.031">10.1016/j.neuron.2020.05.031</a>'
  apa: 'Cho, U. H., &#38; Hetzer, M. (2020). Nuclear periphery takes center stage:
    The role of nuclear pore complexes in cell identity and aging. <i>Neuron</i>.
    Elsevier. <a href="https://doi.org/10.1016/j.neuron.2020.05.031">https://doi.org/10.1016/j.neuron.2020.05.031</a>'
  chicago: 'Cho, Ukrae H., and Martin Hetzer. “Nuclear Periphery Takes Center Stage:
    The Role of Nuclear Pore Complexes in Cell Identity and Aging.” <i>Neuron</i>.
    Elsevier, 2020. <a href="https://doi.org/10.1016/j.neuron.2020.05.031">https://doi.org/10.1016/j.neuron.2020.05.031</a>.'
  ieee: 'U. H. Cho and M. Hetzer, “Nuclear periphery takes center stage: The role
    of nuclear pore complexes in cell identity and aging,” <i>Neuron</i>, vol. 106,
    no. 6. Elsevier, pp. 899–911, 2020.'
  ista: 'Cho UH, Hetzer M. 2020. Nuclear periphery takes center stage: The role of
    nuclear pore complexes in cell identity and aging. Neuron. 106(6), 899–911.'
  mla: 'Cho, Ukrae H., and Martin Hetzer. “Nuclear Periphery Takes Center Stage: The
    Role of Nuclear Pore Complexes in Cell Identity and Aging.” <i>Neuron</i>, vol.
    106, no. 6, Elsevier, 2020, pp. 899–911, doi:<a href="https://doi.org/10.1016/j.neuron.2020.05.031">10.1016/j.neuron.2020.05.031</a>.'
  short: U.H. Cho, M. Hetzer, Neuron 106 (2020) 899–911.
date_created: 2022-04-07T07:43:36Z
date_published: 2020-06-17T00:00:00Z
date_updated: 2022-07-18T08:29:35Z
day: '17'
doi: 10.1016/j.neuron.2020.05.031
extern: '1'
external_id:
  pmid:
  - '32553207'
intvolume: '       106'
issue: '6'
keyword:
- General Neuroscience
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.neuron.2020.05.031
month: '06'
oa: 1
oa_version: Published Version
page: 899-911
pmid: 1
publication: Neuron
publication_identifier:
  issn:
  - 0896-6273
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Nuclear periphery takes center stage: The role of nuclear pore complexes in
  cell identity and aging'
type: journal_article
user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd
volume: 106
year: '2020'
...
---
_id: '11055'
abstract:
- lang: eng
  text: Vascular dysfunctions are a common feature of multiple age-related diseases.
    However, modeling healthy and pathological aging of the human vasculature represents
    an unresolved experimental challenge. Here, we generated induced vascular endothelial
    cells (iVECs) and smooth muscle cells (iSMCs) by direct reprogramming of healthy
    human fibroblasts from donors of different ages and Hutchinson-Gilford Progeria
    Syndrome (HGPS) patients. iVECs induced from old donors revealed upregulation
    of GSTM1 and PALD1, genes linked to oxidative stress, inflammation and endothelial
    junction stability, as vascular aging markers. A functional assay performed on
    PALD1 KD VECs demonstrated a recovery in vascular permeability. We found that
    iSMCs from HGPS donors overexpressed bone morphogenetic protein (BMP)−4, which
    plays a key role in both vascular calcification and endothelial barrier damage
    observed in HGPS. Strikingly, BMP4 concentrations are higher in serum from HGPS
    vs. age-matched mice. Furthermore, targeting BMP4 with blocking antibody recovered
    the functionality of the vascular barrier in vitro, hence representing a potential
    future therapeutic strategy to limit cardiovascular dysfunction in HGPS. These
    results show that iVECs and iSMCs retain disease-related signatures, allowing
    modeling of vascular aging and HGPS in vitro.
article_number: e54383
article_processing_charge: No
article_type: original
author:
- first_name: Simone
  full_name: Bersini, Simone
  last_name: Bersini
- first_name: Roberta
  full_name: Schulte, Roberta
  last_name: Schulte
- first_name: Ling
  full_name: Huang, Ling
  last_name: Huang
- first_name: Hannah
  full_name: Tsai, Hannah
  last_name: Tsai
- first_name: Martin W
  full_name: HETZER, Martin W
  id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
  last_name: HETZER
  orcid: 0000-0002-2111-992X
citation:
  ama: Bersini S, Schulte R, Huang L, Tsai H, Hetzer M. Direct reprogramming of human
    smooth muscle and vascular endothelial cells reveals defects associated with aging
    and Hutchinson-Gilford progeria syndrome. <i>eLife</i>. 2020;9. doi:<a href="https://doi.org/10.7554/elife.54383">10.7554/elife.54383</a>
  apa: Bersini, S., Schulte, R., Huang, L., Tsai, H., &#38; Hetzer, M. (2020). Direct
    reprogramming of human smooth muscle and vascular endothelial cells reveals defects
    associated with aging and Hutchinson-Gilford progeria syndrome. <i>ELife</i>.
    eLife Sciences Publications. <a href="https://doi.org/10.7554/elife.54383">https://doi.org/10.7554/elife.54383</a>
  chicago: Bersini, Simone, Roberta Schulte, Ling Huang, Hannah Tsai, and Martin Hetzer.
    “Direct Reprogramming of Human Smooth Muscle and Vascular Endothelial Cells Reveals
    Defects Associated with Aging and Hutchinson-Gilford Progeria Syndrome.” <i>ELife</i>.
    eLife Sciences Publications, 2020. <a href="https://doi.org/10.7554/elife.54383">https://doi.org/10.7554/elife.54383</a>.
  ieee: S. Bersini, R. Schulte, L. Huang, H. Tsai, and M. Hetzer, “Direct reprogramming
    of human smooth muscle and vascular endothelial cells reveals defects associated
    with aging and Hutchinson-Gilford progeria syndrome,” <i>eLife</i>, vol. 9. eLife
    Sciences Publications, 2020.
  ista: Bersini S, Schulte R, Huang L, Tsai H, Hetzer M. 2020. Direct reprogramming
    of human smooth muscle and vascular endothelial cells reveals defects associated
    with aging and Hutchinson-Gilford progeria syndrome. eLife. 9, e54383.
  mla: Bersini, Simone, et al. “Direct Reprogramming of Human Smooth Muscle and Vascular
    Endothelial Cells Reveals Defects Associated with Aging and Hutchinson-Gilford
    Progeria Syndrome.” <i>ELife</i>, vol. 9, e54383, eLife Sciences Publications,
    2020, doi:<a href="https://doi.org/10.7554/elife.54383">10.7554/elife.54383</a>.
  short: S. Bersini, R. Schulte, L. Huang, H. Tsai, M. Hetzer, ELife 9 (2020).
date_created: 2022-04-07T07:43:48Z
date_published: 2020-09-08T00:00:00Z
date_updated: 2022-07-18T08:30:37Z
day: '08'
ddc:
- '570'
doi: 10.7554/elife.54383
extern: '1'
external_id:
  pmid:
  - '32896271'
file:
- access_level: open_access
  checksum: f8b3821349a194050be02570d8fe7d4b
  content_type: application/pdf
  creator: dernst
  date_created: 2022-04-08T06:53:10Z
  date_updated: 2022-04-08T06:53:10Z
  file_id: '11132'
  file_name: 2020_eLife_Bersini.pdf
  file_size: 4399825
  relation: main_file
  success: 1
file_date_updated: 2022-04-08T06:53:10Z
has_accepted_license: '1'
intvolume: '         9'
keyword:
- General Immunology and Microbiology
- General Biochemistry
- Genetics and Molecular Biology
- General Medicine
- General Neuroscience
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
pmid: 1
publication: eLife
publication_identifier:
  issn:
  - 2050-084X
publication_status: published
publisher: eLife Sciences Publications
quality_controlled: '1'
scopus_import: '1'
status: public
title: Direct reprogramming of human smooth muscle and vascular endothelial cells
  reveals defects associated with aging and Hutchinson-Gilford progeria syndrome
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd
volume: 9
year: '2020'
...
---
_id: '11056'
abstract:
- lang: eng
  text: Aging of the circulatory system correlates with the pathogenesis of a large
    spectrum of diseases. However, it is largely unknown which factors drive the age-dependent
    or pathological decline of the vasculature and how vascular defects relate to
    tissue aging. The goal of the study is to design a multianalytical approach to
    identify how the cellular microenvironment (i.e., fibroblasts) and serum from
    healthy donors of different ages or Alzheimer disease (AD) patients can modulate
    the functionality of organ-specific vascular endothelial cells (VECs). Long-living
    human microvascular networks embedding VECs and fibroblasts from skin biopsies
    are generated. RNA-seq, secretome analyses, and microfluidic assays demonstrate
    that fibroblasts from young donors restore the functionality of aged endothelial
    cells, an effect also achieved by serum from young donors. New biomarkers of vascular
    aging are validated in human biopsies and it is shown that young serum induces
    angiopoietin-like-4, which can restore compromised vascular barriers. This strategy
    is then employed to characterize transcriptional/functional changes induced on
    the blood–brain barrier by AD serum, demonstrating the importance of PTP4A3 in
    the regulation of permeability. Features of vascular degeneration during aging
    and AD are recapitulated, and a tool to identify novel biomarkers that can be
    exploited to develop future therapeutics modulating vascular function is established.
article_number: '2000044'
article_processing_charge: No
article_type: original
author:
- first_name: Simone
  full_name: Bersini, Simone
  last_name: Bersini
- first_name: Rafael
  full_name: Arrojo e Drigo, Rafael
  last_name: Arrojo e Drigo
- first_name: Ling
  full_name: Huang, Ling
  last_name: Huang
- first_name: Maxim N.
  full_name: Shokhirev, Maxim N.
  last_name: Shokhirev
- first_name: Martin W
  full_name: HETZER, Martin W
  id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
  last_name: HETZER
  orcid: 0000-0002-2111-992X
citation:
  ama: Bersini S, Arrojo e Drigo R, Huang L, Shokhirev MN, Hetzer M. Transcriptional
    and functional changes of the human microvasculature during physiological aging
    and Alzheimer disease. <i>Advanced Biosystems</i>. 2020;4(5). doi:<a href="https://doi.org/10.1002/adbi.202000044">10.1002/adbi.202000044</a>
  apa: Bersini, S., Arrojo e Drigo, R., Huang, L., Shokhirev, M. N., &#38; Hetzer,
    M. (2020). Transcriptional and functional changes of the human microvasculature
    during physiological aging and Alzheimer disease. <i>Advanced Biosystems</i>.
    Wiley. <a href="https://doi.org/10.1002/adbi.202000044">https://doi.org/10.1002/adbi.202000044</a>
  chicago: Bersini, Simone, Rafael Arrojo e Drigo, Ling Huang, Maxim N. Shokhirev,
    and Martin Hetzer. “Transcriptional and Functional Changes of the Human Microvasculature
    during Physiological Aging and Alzheimer Disease.” <i>Advanced Biosystems</i>.
    Wiley, 2020. <a href="https://doi.org/10.1002/adbi.202000044">https://doi.org/10.1002/adbi.202000044</a>.
  ieee: S. Bersini, R. Arrojo e Drigo, L. Huang, M. N. Shokhirev, and M. Hetzer, “Transcriptional
    and functional changes of the human microvasculature during physiological aging
    and Alzheimer disease,” <i>Advanced Biosystems</i>, vol. 4, no. 5. Wiley, 2020.
  ista: Bersini S, Arrojo e Drigo R, Huang L, Shokhirev MN, Hetzer M. 2020. Transcriptional
    and functional changes of the human microvasculature during physiological aging
    and Alzheimer disease. Advanced Biosystems. 4(5), 2000044.
  mla: Bersini, Simone, et al. “Transcriptional and Functional Changes of the Human
    Microvasculature during Physiological Aging and Alzheimer Disease.” <i>Advanced
    Biosystems</i>, vol. 4, no. 5, 2000044, Wiley, 2020, doi:<a href="https://doi.org/10.1002/adbi.202000044">10.1002/adbi.202000044</a>.
  short: S. Bersini, R. Arrojo e Drigo, L. Huang, M.N. Shokhirev, M. Hetzer, Advanced
    Biosystems 4 (2020).
date_created: 2022-04-07T07:43:57Z
date_published: 2020-05-01T00:00:00Z
date_updated: 2022-07-18T08:30:48Z
day: '01'
ddc:
- '570'
doi: 10.1002/adbi.202000044
extern: '1'
external_id:
  pmid:
  - '32402127'
file:
- access_level: open_access
  checksum: 5584d9a1609812dc75c02ce1e35d2ec0
  content_type: application/pdf
  creator: dernst
  date_created: 2022-04-08T07:06:05Z
  date_updated: 2022-04-08T07:06:05Z
  file_id: '11134'
  file_name: 2020_AdvancedBiosystems_Bersini.pdf
  file_size: 2490829
  relation: main_file
  success: 1
file_date_updated: 2022-04-08T07:06:05Z
has_accepted_license: '1'
intvolume: '         4'
issue: '5'
keyword:
- General Biochemistry
- Genetics and Molecular Biology
- Biomedical Engineering
- Biomaterials
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '05'
oa: 1
oa_version: Published Version
pmid: 1
publication: Advanced Biosystems
publication_identifier:
  issn:
  - 2366-7478
  - 2366-7478
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Transcriptional and functional changes of the human microvasculature during
  physiological aging and Alzheimer disease
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd
volume: 4
year: '2020'
...
---
_id: '11057'
abstract:
- lang: eng
  text: During mitosis, transcription of genomic DNA is dramatically reduced, before
    it is reactivated during nuclear reformation in anaphase/telophase. Many aspects
    of the underlying principles that mediate transcriptional memory and reactivation
    in the daughter cells remain unclear. Here, we used ChIP-seq on synchronized cells
    at different stages after mitosis to generate genome-wide maps of histone modifications.
    Combined with EU-RNA-seq and Hi-C analyses, we found that during prometaphase,
    promoters, enhancers, and insulators retain H3K4me3 and H3K4me1, while losing
    H3K27ac. Enhancers globally retaining mitotic H3K4me1 or locally retaining mitotic
    H3K27ac are associated with cell type-specific genes and their transcription factors
    for rapid transcriptional activation. As cells exit mitosis, promoters regain
    H3K27ac, which correlates with transcriptional reactivation. Insulators also gain
    H3K27ac and CCCTC-binding factor (CTCF) in anaphase/telophase. This increase of
    H3K27ac in anaphase/telophase is required for posttranscriptional activation and
    may play a role in the establishment of topologically associating domains (TADs).
    Together, our results suggest that the genome is reorganized in a sequential order,
    in which histone methylations occur first in prometaphase, histone acetylation,
    and CTCF in anaphase/telophase, transcription in cytokinesis, and long-range chromatin
    interactions in early G1. We thus provide insights into the histone modification
    landscape that allows faithful reestablishment of the transcriptional program
    and TADs during cell division.
article_processing_charge: No
article_type: original
author:
- first_name: Hyeseon
  full_name: Kang, Hyeseon
  last_name: Kang
- first_name: Maxim N.
  full_name: Shokhirev, Maxim N.
  last_name: Shokhirev
- first_name: Zhichao
  full_name: Xu, Zhichao
  last_name: Xu
- first_name: Sahaana
  full_name: Chandran, Sahaana
  last_name: Chandran
- first_name: Jesse R.
  full_name: Dixon, Jesse R.
  last_name: Dixon
- first_name: Martin W
  full_name: HETZER, Martin W
  id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
  last_name: HETZER
  orcid: 0000-0002-2111-992X
citation:
  ama: Kang H, Shokhirev MN, Xu Z, Chandran S, Dixon JR, Hetzer M. Dynamic regulation
    of histone modifications and long-range chromosomal interactions during postmitotic
    transcriptional reactivation. <i>Genes &#38; Development</i>. 2020;34(13-14):913-930.
    doi:<a href="https://doi.org/10.1101/gad.335794.119">10.1101/gad.335794.119</a>
  apa: Kang, H., Shokhirev, M. N., Xu, Z., Chandran, S., Dixon, J. R., &#38; Hetzer,
    M. (2020). Dynamic regulation of histone modifications and long-range chromosomal
    interactions during postmitotic transcriptional reactivation. <i>Genes &#38; Development</i>.
    Cold Spring Harbor Laboratory Press. <a href="https://doi.org/10.1101/gad.335794.119">https://doi.org/10.1101/gad.335794.119</a>
  chicago: Kang, Hyeseon, Maxim N. Shokhirev, Zhichao Xu, Sahaana Chandran, Jesse
    R. Dixon, and Martin Hetzer. “Dynamic Regulation of Histone Modifications and
    Long-Range Chromosomal Interactions during Postmitotic Transcriptional Reactivation.”
    <i>Genes &#38; Development</i>. Cold Spring Harbor Laboratory Press, 2020. <a
    href="https://doi.org/10.1101/gad.335794.119">https://doi.org/10.1101/gad.335794.119</a>.
  ieee: H. Kang, M. N. Shokhirev, Z. Xu, S. Chandran, J. R. Dixon, and M. Hetzer,
    “Dynamic regulation of histone modifications and long-range chromosomal interactions
    during postmitotic transcriptional reactivation,” <i>Genes &#38; Development</i>,
    vol. 34, no. 13–14. Cold Spring Harbor Laboratory Press, pp. 913–930, 2020.
  ista: Kang H, Shokhirev MN, Xu Z, Chandran S, Dixon JR, Hetzer M. 2020. Dynamic
    regulation of histone modifications and long-range chromosomal interactions during
    postmitotic transcriptional reactivation. Genes &#38; Development. 34(13–14),
    913–930.
  mla: Kang, Hyeseon, et al. “Dynamic Regulation of Histone Modifications and Long-Range
    Chromosomal Interactions during Postmitotic Transcriptional Reactivation.” <i>Genes
    &#38; Development</i>, vol. 34, no. 13–14, Cold Spring Harbor Laboratory Press,
    2020, pp. 913–30, doi:<a href="https://doi.org/10.1101/gad.335794.119">10.1101/gad.335794.119</a>.
  short: H. Kang, M.N. Shokhirev, Z. Xu, S. Chandran, J.R. Dixon, M. Hetzer, Genes
    &#38; Development 34 (2020) 913–930.
date_created: 2022-04-07T07:44:09Z
date_published: 2020-04-28T00:00:00Z
date_updated: 2022-07-18T08:31:08Z
day: '28'
ddc:
- '570'
doi: 10.1101/gad.335794.119
extern: '1'
external_id:
  pmid:
  - '32499403'
file:
- access_level: open_access
  checksum: 84e92d40e67936c739628315c238daf9
  content_type: application/pdf
  creator: dernst
  date_created: 2022-04-08T07:12:33Z
  date_updated: 2022-04-08T07:12:33Z
  file_id: '11136'
  file_name: 2020_GenesDevelopment_Kang.pdf
  file_size: 4406772
  relation: main_file
  success: 1
file_date_updated: 2022-04-08T07:12:33Z
has_accepted_license: '1'
intvolume: '        34'
issue: 13-14
keyword:
- Developmental Biology
- Genetics
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 913-930
pmid: 1
publication: Genes & Development
publication_identifier:
  issn:
  - 0890-9369
  - 1549-5477
publication_status: published
publisher: Cold Spring Harbor Laboratory Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Dynamic regulation of histone modifications and long-range chromosomal interactions
  during postmitotic transcriptional reactivation
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd
volume: 34
year: '2020'
...
---
_id: '11058'
abstract:
- lang: eng
  text: Nucleoporin 93 (Nup93) expression inversely correlates with the survival of
    triple-negative breast cancer patients. However, our knowledge of Nup93 function
    in breast cancer besides its role as structural component of the nuclear pore
    complex is not understood. Combination of functional assays and genetic analyses
    suggested that chromatin interaction of Nup93 partially modulates the expression
    of genes associated with actin cytoskeleton remodeling and epithelial to mesenchymal
    transition, resulting in impaired invasion of triple-negative, claudin-low breast
    cancer cells. Nup93 depletion induced stress fiber formation associated with reduced
    cell migration/proliferation and impaired expression of mesenchymal-like genes.
    Silencing LIMCH1, a gene responsible for actin cytoskeleton remodeling and up-regulated
    upon Nup93 depletion, partially restored the invasive phenotype of cancer cells.
    Loss of Nup93 led to significant defects in tumor establishment/propagation in
    vivo, whereas patient samples revealed that high Nup93 and low LIMCH1 expression
    correlate with late tumor stage. Our approach identified Nup93 as contributor
    of triple-negative, claudin-low breast cancer cell invasion and paves the way
    to study the role of nuclear envelope proteins during breast cancer tumorigenesis.
article_number: e201900623
article_processing_charge: No
article_type: original
author:
- first_name: Simone
  full_name: Bersini, Simone
  last_name: Bersini
- first_name: Nikki K
  full_name: Lytle, Nikki K
  last_name: Lytle
- first_name: Roberta
  full_name: Schulte, Roberta
  last_name: Schulte
- first_name: Ling
  full_name: Huang, Ling
  last_name: Huang
- first_name: Geoffrey M
  full_name: Wahl, Geoffrey M
  last_name: Wahl
- first_name: Martin W
  full_name: HETZER, Martin W
  id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
  last_name: HETZER
  orcid: 0000-0002-2111-992X
citation:
  ama: Bersini S, Lytle NK, Schulte R, Huang L, Wahl GM, Hetzer M. Nup93 regulates
    breast tumor growth by modulating cell proliferation and actin cytoskeleton remodeling.
    <i>Life Science Alliance</i>. 2020;3(1). doi:<a href="https://doi.org/10.26508/lsa.201900623">10.26508/lsa.201900623</a>
  apa: Bersini, S., Lytle, N. K., Schulte, R., Huang, L., Wahl, G. M., &#38; Hetzer,
    M. (2020). Nup93 regulates breast tumor growth by modulating cell proliferation
    and actin cytoskeleton remodeling. <i>Life Science Alliance</i>. Life Science
    Alliance. <a href="https://doi.org/10.26508/lsa.201900623">https://doi.org/10.26508/lsa.201900623</a>
  chicago: Bersini, Simone, Nikki K Lytle, Roberta Schulte, Ling Huang, Geoffrey M
    Wahl, and Martin Hetzer. “Nup93 Regulates Breast Tumor Growth by Modulating Cell
    Proliferation and Actin Cytoskeleton Remodeling.” <i>Life Science Alliance</i>.
    Life Science Alliance, 2020. <a href="https://doi.org/10.26508/lsa.201900623">https://doi.org/10.26508/lsa.201900623</a>.
  ieee: S. Bersini, N. K. Lytle, R. Schulte, L. Huang, G. M. Wahl, and M. Hetzer,
    “Nup93 regulates breast tumor growth by modulating cell proliferation and actin
    cytoskeleton remodeling,” <i>Life Science Alliance</i>, vol. 3, no. 1. Life Science
    Alliance, 2020.
  ista: Bersini S, Lytle NK, Schulte R, Huang L, Wahl GM, Hetzer M. 2020. Nup93 regulates
    breast tumor growth by modulating cell proliferation and actin cytoskeleton remodeling.
    Life Science Alliance. 3(1), e201900623.
  mla: Bersini, Simone, et al. “Nup93 Regulates Breast Tumor Growth by Modulating
    Cell Proliferation and Actin Cytoskeleton Remodeling.” <i>Life Science Alliance</i>,
    vol. 3, no. 1, e201900623, Life Science Alliance, 2020, doi:<a href="https://doi.org/10.26508/lsa.201900623">10.26508/lsa.201900623</a>.
  short: S. Bersini, N.K. Lytle, R. Schulte, L. Huang, G.M. Wahl, M. Hetzer, Life
    Science Alliance 3 (2020).
date_created: 2022-04-07T07:44:18Z
date_published: 2020-01-01T00:00:00Z
date_updated: 2022-07-18T08:31:20Z
day: '01'
ddc:
- '570'
doi: 10.26508/lsa.201900623
extern: '1'
external_id:
  pmid:
  - '31959624'
file:
- access_level: open_access
  checksum: 3bf33e7e93bef7823287807206b69b38
  content_type: application/pdf
  creator: dernst
  date_created: 2022-04-08T07:33:01Z
  date_updated: 2022-04-08T07:33:01Z
  file_id: '11137'
  file_name: 2020_LifeScienceAlliance_Bersini.pdf
  file_size: 2653960
  relation: main_file
  success: 1
file_date_updated: 2022-04-08T07:33:01Z
has_accepted_license: '1'
intvolume: '         3'
issue: '1'
keyword:
- Health
- Toxicology and Mutagenesis
- Plant Science
- Biochemistry
- Genetics and Molecular Biology (miscellaneous)
- Ecology
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
pmid: 1
publication: Life Science Alliance
publication_identifier:
  issn:
  - 2575-1077
publication_status: published
publisher: Life Science Alliance
quality_controlled: '1'
scopus_import: '1'
status: public
title: Nup93 regulates breast tumor growth by modulating cell proliferation and actin
  cytoskeleton remodeling
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd
volume: 3
year: '2020'
...
---
_id: '11501'
abstract:
- lang: eng
  text: We investigated the ultraviolet (UV) spectral properties of faint Lyman-α
    emitters (LAEs) in the redshift range 2.9 ≤ z ≤ 4.6, and we provide material to
    prepare future observations of the faint Universe. We used data from the MUSE
    Hubble Ultra Deep Survey to construct mean rest-frame spectra of continuum-faint
    (median MUV of −18 and down to MUV of −16), low stellar mass (median value of
    108.4 M⊙ and down to 107 M⊙) LAEs at redshift z ≳ 3. We computed various averaged
    spectra of LAEs, subsampled on the basis of their observational (e.g., Lyα strength,
    UV magnitude and spectral slope) and physical (e.g., stellar mass and star-formation
    rate) properties. We searched for UV spectral features other than Lyα, such as
    higher ionization nebular emission lines and absorption features. We successfully
    observed the O III]λ1666 and [C III]λ1907+C III]λ1909 collisionally excited emission
    lines and the He IIλ1640 recombination feature, as well as the resonant C IVλλ1548,1551
    doublet either in emission or P-Cygni. We compared the observed spectral properties
    of the different mean spectra and find the emission lines to vary with the observational
    and physical properties of the LAEs. In particular, the mean spectra of LAEs with
    larger Lyα equivalent widths, fainter UV magnitudes, bluer UV spectral slopes,
    and lower stellar masses show the strongest nebular emission. The line ratios
    of these lines are similar to those measured in the spectra of local metal-poor
    galaxies, while their equivalent widths are weaker compared to the handful of
    extreme values detected in individual spectra of z >  2 galaxies. This suggests
    that weak UV features are likely ubiquitous in high z, low-mass, and faint LAEs.
    We publicly released the stacked spectra, as they can serve as empirical templates
    for the design of future observations, such as those with the James Webb Space
    Telescope and the Extremely Large Telescope.
acknowledgement: 'We thank Margherita Talia, Stéphane Charlot, Adele Plat and Alba
  Vidal-García for helpful discussions. This work is supported by the ERC advanced
  grant 339659-MUSICOS (R. Bacon). AF acknowledges the support from grant PRIN MIUR
  2017 20173ML3WW. MVM and JP would like to thank the Leiden/ESA Astrophysics Program
  for Summer Students (LEAPS) for funding at the outset of this project. FL, HK, and
  AV acknowledge support from the ERC starting grant ERC-757258-TRIPLE. TH was supported
  by Leading Initiative for Excellent Young Researchers, MEXT, Japan. JB acknowledges
  support by FCT/MCTES through national funds by the grant UID/FIS/04434/2019, UIDB/04434/2020
  and UIDP/04434/2020 and through the Investigador FCT Contract No. IF/01654/2014/CP1215/CT0003.
  HI acknowledges support from JSPS KAKENHI Grant Number JP19K23462. We would also
  like to thank the organizers and participants of the Leiden Lorentz Center workshop:
  Revolutionary Spectroscopy of Today as a Springboard to Webb. This work made use
  of several open source python packages: NUMPY (van der Walt et al. 2011), MATPLOTLIB
  (Hunter 2007), ASTROPY (Astropy Collaboration 2013) and MPDAF (MUSE Python Data
  Analysis Framework, Piqueras et al. 2019).'
article_number: A118
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Anna
  full_name: Feltre, Anna
  last_name: Feltre
- first_name: Michael V.
  full_name: Maseda, Michael V.
  last_name: Maseda
- first_name: Roland
  full_name: Bacon, Roland
  last_name: Bacon
- first_name: Jayadev
  full_name: Pradeep, Jayadev
  last_name: Pradeep
- first_name: Floriane
  full_name: Leclercq, Floriane
  last_name: Leclercq
- first_name: Haruka
  full_name: Kusakabe, Haruka
  last_name: Kusakabe
- first_name: Lutz
  full_name: Wisotzki, Lutz
  last_name: Wisotzki
- first_name: Takuya
  full_name: Hashimoto, Takuya
  last_name: Hashimoto
- first_name: Kasper B.
  full_name: Schmidt, Kasper B.
  last_name: Schmidt
- first_name: Jeremy
  full_name: Blaizot, Jeremy
  last_name: Blaizot
- first_name: Jarle
  full_name: Brinchmann, Jarle
  last_name: Brinchmann
- first_name: Leindert
  full_name: Boogaard, Leindert
  last_name: Boogaard
- first_name: Sebastiano
  full_name: Cantalupo, Sebastiano
  last_name: Cantalupo
- first_name: David
  full_name: Carton, David
  last_name: Carton
- first_name: Hanae
  full_name: Inami, Hanae
  last_name: Inami
- first_name: Wolfram
  full_name: Kollatschny, Wolfram
  last_name: Kollatschny
- first_name: Raffaella A.
  full_name: Marino, Raffaella A.
  last_name: Marino
- first_name: Jorryt J
  full_name: Matthee, Jorryt J
  id: 7439a258-f3c0-11ec-9501-9df22fe06720
  last_name: Matthee
  orcid: 0000-0003-2871-127X
- first_name: Themiya
  full_name: Nanayakkara, Themiya
  last_name: Nanayakkara
- first_name: Johan
  full_name: Richard, Johan
  last_name: Richard
- first_name: Joop
  full_name: Schaye, Joop
  last_name: Schaye
- first_name: Laurence
  full_name: Tresse, Laurence
  last_name: Tresse
- first_name: Tanya
  full_name: Urrutia, Tanya
  last_name: Urrutia
- first_name: Anne
  full_name: Verhamme, Anne
  last_name: Verhamme
- first_name: Peter M.
  full_name: Weilbacher, Peter M.
  last_name: Weilbacher
citation:
  ama: 'Feltre A, Maseda MV, Bacon R, et al. The MUSE Hubble Ultra Deep Field Survey:
    XV. The mean rest-UV spectra of Lyα emitters at z &#62; 3. <i>Astronomy &#38;
    Astrophysics</i>. 2020;641. doi:<a href="https://doi.org/10.1051/0004-6361/202038133">10.1051/0004-6361/202038133</a>'
  apa: 'Feltre, A., Maseda, M. V., Bacon, R., Pradeep, J., Leclercq, F., Kusakabe,
    H., … Weilbacher, P. M. (2020). The MUSE Hubble Ultra Deep Field Survey: XV. The
    mean rest-UV spectra of Lyα emitters at z &#62; 3. <i>Astronomy &#38; Astrophysics</i>.
    EDP Sciences. <a href="https://doi.org/10.1051/0004-6361/202038133">https://doi.org/10.1051/0004-6361/202038133</a>'
  chicago: 'Feltre, Anna, Michael V. Maseda, Roland Bacon, Jayadev Pradeep, Floriane
    Leclercq, Haruka Kusakabe, Lutz Wisotzki, et al. “The MUSE Hubble Ultra Deep Field
    Survey: XV. The Mean Rest-UV Spectra of Lyα Emitters at z &#62; 3.” <i>Astronomy
    &#38; Astrophysics</i>. EDP Sciences, 2020. <a href="https://doi.org/10.1051/0004-6361/202038133">https://doi.org/10.1051/0004-6361/202038133</a>.'
  ieee: 'A. Feltre <i>et al.</i>, “The MUSE Hubble Ultra Deep Field Survey: XV. The
    mean rest-UV spectra of Lyα emitters at z &#62; 3,” <i>Astronomy &#38; Astrophysics</i>,
    vol. 641. EDP Sciences, 2020.'
  ista: 'Feltre A, Maseda MV, Bacon R, Pradeep J, Leclercq F, Kusakabe H, Wisotzki
    L, Hashimoto T, Schmidt KB, Blaizot J, Brinchmann J, Boogaard L, Cantalupo S,
    Carton D, Inami H, Kollatschny W, Marino RA, Matthee JJ, Nanayakkara T, Richard
    J, Schaye J, Tresse L, Urrutia T, Verhamme A, Weilbacher PM. 2020. The MUSE Hubble
    Ultra Deep Field Survey: XV. The mean rest-UV spectra of Lyα emitters at z &#62;
    3. Astronomy &#38; Astrophysics. 641, A118.'
  mla: 'Feltre, Anna, et al. “The MUSE Hubble Ultra Deep Field Survey: XV. The Mean
    Rest-UV Spectra of Lyα Emitters at z &#62; 3.” <i>Astronomy &#38; Astrophysics</i>,
    vol. 641, A118, EDP Sciences, 2020, doi:<a href="https://doi.org/10.1051/0004-6361/202038133">10.1051/0004-6361/202038133</a>.'
  short: A. Feltre, M.V. Maseda, R. Bacon, J. Pradeep, F. Leclercq, H. Kusakabe, L.
    Wisotzki, T. Hashimoto, K.B. Schmidt, J. Blaizot, J. Brinchmann, L. Boogaard,
    S. Cantalupo, D. Carton, H. Inami, W. Kollatschny, R.A. Marino, J.J. Matthee,
    T. Nanayakkara, J. Richard, J. Schaye, L. Tresse, T. Urrutia, A. Verhamme, P.M.
    Weilbacher, Astronomy &#38; Astrophysics 641 (2020).
date_created: 2022-07-06T09:38:16Z
date_published: 2020-09-18T00:00:00Z
date_updated: 2022-07-19T09:35:43Z
day: '18'
doi: 10.1051/0004-6361/202038133
extern: '1'
external_id:
  arxiv:
  - '2007.01878'
intvolume: '       641'
keyword:
- Space and Planetary Science
- Astronomy and Astrophysics
- 'galaxies: evolution / galaxies: high-redshift / ISM: lines and bands / ultraviolet:
  ISM / ultraviolet: galaxies'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2007.01878
month: '09'
oa: 1
oa_version: Published Version
publication: Astronomy & Astrophysics
publication_identifier:
  eissn:
  - 1432-0746
  issn:
  - 0004-6361
publication_status: published
publisher: EDP Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'The MUSE Hubble Ultra Deep Field Survey: XV. The mean rest-UV spectra of Lyα
  emitters at z > 3'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 641
year: '2020'
...
