---
_id: '12016'
abstract:
- lang: eng
text: We consider the problem of coded distributed computing using polar codes.
The average execution time of a coded computing system is related to the error
probability for transmission over the binary erasure channel in recent work by
Soleymani, Jamali and Mahdavifar, where the performance of binary linear codes
is investigated. In this paper, we focus on polar codes and unveil a connection
between the average execution time and the scaling exponent μ of the family of
codes. In the finite-length characterization of polar codes, the scaling exponent
is a key object capturing the speed of convergence to capacity. In particular,
we show that (i) the gap between the normalized average execution time of polar
codes and that of optimal MDS codes is O(n –1/μ ), and (ii) this upper bound can
be improved to roughly O(n –1/2 ) by considering polar codes with large kernels.
We conjecture that these bounds could be improved to O(n –2/μ ) and O(n –1 ),
respectively, and provide a heuristic argument as well as numerical evidence supporting
this view.
acknowledgement: D. Fathollahi and M. Mondelli were partially supported by the 2019
Lopez-Loreta Prize. The authors thank Hamed Hassani and Hessam Mahdavifar for helpful
discussions.
article_processing_charge: No
arxiv: 1
author:
- first_name: Dorsa
full_name: Fathollahi, Dorsa
last_name: Fathollahi
- first_name: Marco
full_name: Mondelli, Marco
id: 27EB676C-8706-11E9-9510-7717E6697425
last_name: Mondelli
orcid: 0000-0002-3242-7020
citation:
ama: 'Fathollahi D, Mondelli M. Polar coded computing: The role of the scaling exponent.
In: 2022 IEEE International Symposium on Information Theory. Vol 2022.
IEEE; 2022:2154-2159. doi:10.1109/ISIT50566.2022.9834712'
apa: 'Fathollahi, D., & Mondelli, M. (2022). Polar coded computing: The role
of the scaling exponent. In 2022 IEEE International Symposium on Information
Theory (Vol. 2022, pp. 2154–2159). Espoo, Finland: IEEE. https://doi.org/10.1109/ISIT50566.2022.9834712'
chicago: 'Fathollahi, Dorsa, and Marco Mondelli. “Polar Coded Computing: The Role
of the Scaling Exponent.” In 2022 IEEE International Symposium on Information
Theory, 2022:2154–59. IEEE, 2022. https://doi.org/10.1109/ISIT50566.2022.9834712.'
ieee: 'D. Fathollahi and M. Mondelli, “Polar coded computing: The role of the scaling
exponent,” in 2022 IEEE International Symposium on Information Theory,
Espoo, Finland, 2022, vol. 2022, pp. 2154–2159.'
ista: 'Fathollahi D, Mondelli M. 2022. Polar coded computing: The role of the scaling
exponent. 2022 IEEE International Symposium on Information Theory. ISIT: Internation
Symposium on Information Theory vol. 2022, 2154–2159.'
mla: 'Fathollahi, Dorsa, and Marco Mondelli. “Polar Coded Computing: The Role of
the Scaling Exponent.” 2022 IEEE International Symposium on Information Theory,
vol. 2022, IEEE, 2022, pp. 2154–59, doi:10.1109/ISIT50566.2022.9834712.'
short: D. Fathollahi, M. Mondelli, in:, 2022 IEEE International Symposium on Information
Theory, IEEE, 2022, pp. 2154–2159.
conference:
end_date: 2022-07-01
location: Espoo, Finland
name: 'ISIT: Internation Symposium on Information Theory'
start_date: 2022-06-26
date_created: 2022-09-04T22:02:05Z
date_published: 2022-08-03T00:00:00Z
date_updated: 2024-09-10T13:03:17Z
day: '03'
department:
- _id: MaMo
doi: 10.1109/ISIT50566.2022.9834712
external_id:
arxiv:
- '2201.10082'
intvolume: ' 2022'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.2201.10082
month: '08'
oa: 1
oa_version: Preprint
page: 2154-2159
project:
- _id: 059876FA-7A3F-11EA-A408-12923DDC885E
name: Prix Lopez-Loretta 2019 - Marco Mondelli
publication: 2022 IEEE International Symposium on Information Theory
publication_identifier:
isbn:
- '9781665421591'
issn:
- 2157-8095
publication_status: published
publisher: IEEE
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Polar coded computing: The role of the scaling exponent'
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2022
year: '2022'
...
---
_id: '12017'
abstract:
- lang: eng
text: 'In the classic adversarial communication problem, two parties communicate
over a noisy channel in the presence of a malicious jamming adversary. The arbitrarily
varying channels (AVCs) offer an elegant framework to study a wide range of interesting
adversary models. The optimal throughput or capacity over such AVCs is intimately
tied to the underlying adversary model; in some cases, capacity is unknown and
the problem is known to be notoriously hard. The omniscient adversary, one which
knows the sender’s entire channel transmission a priori, is one of such classic
models of interest; the capacity under such an adversary remains an exciting open
problem. The myopic adversary is a generalization of that model where the adversary’s
observation may be corrupted over a noisy discrete memoryless channel. Through
the adversary’s myopicity, one can unify the slew of different adversary models,
ranging from the omniscient adversary to one that is completely blind to the transmission
(the latter is the well known oblivious model where the capacity is fully characterized).In
this work, we present new results on the capacity under both the omniscient and
myopic adversary models. We completely characterize the positive capacity threshold
over general AVCs with omniscient adversaries. The characterization is in terms
of two key combinatorial objects: the set of completely positive distributions
and the CP-confusability set. For omniscient AVCs with positive capacity, we present
non-trivial lower and upper bounds on the capacity; unlike some of the previous
bounds, our bounds hold under fairly general input and jamming constraints. Our
lower bound improves upon the generalized Gilbert-Varshamov bound for general
AVCs while the upper bound generalizes the well known Elias-Bassalygo bound (known
for binary and q-ary alphabets). For the myopic AVCs, we build on prior results
known for the so-called sufficiently myopic model, and present new results on
the positive rate communication threshold over the so-called insufficiently myopic
regime (a completely insufficient myopic adversary specializes to an omniscient
adversary). We present interesting examples for the widely studied models of adversarial
bit-flip and bit-erasure channels. In fact, for the bit-flip AVC with additive
adversarial noise as well as random noise, we completely characterize the omniscient
model capacity when the random noise is sufficiently large vis-a-vis the adversary’s
budget.'
article_processing_charge: No
author:
- first_name: Anuj Kumar
full_name: Yadav, Anuj Kumar
last_name: Yadav
- first_name: Mohammadreza
full_name: Alimohammadi, Mohammadreza
last_name: Alimohammadi
- first_name: Yihan
full_name: Zhang, Yihan
id: 2ce5da42-b2ea-11eb-bba5-9f264e9d002c
last_name: Zhang
- first_name: Amitalok J.
full_name: Budkuley, Amitalok J.
last_name: Budkuley
- first_name: Sidharth
full_name: Jaggi, Sidharth
last_name: Jaggi
citation:
ama: 'Yadav AK, Alimohammadi M, Zhang Y, Budkuley AJ, Jaggi S. New results on AVCs
with omniscient and myopic adversaries. In: 2022 IEEE International Symposium
on Information Theory. Vol 2022. Institute of Electrical and Electronics Engineers;
2022:2535-2540. doi:10.1109/ISIT50566.2022.9834632'
apa: 'Yadav, A. K., Alimohammadi, M., Zhang, Y., Budkuley, A. J., & Jaggi, S.
(2022). New results on AVCs with omniscient and myopic adversaries. In 2022
IEEE International Symposium on Information Theory (Vol. 2022, pp. 2535–2540).
Espoo, Finland: Institute of Electrical and Electronics Engineers. https://doi.org/10.1109/ISIT50566.2022.9834632'
chicago: Yadav, Anuj Kumar, Mohammadreza Alimohammadi, Yihan Zhang, Amitalok J.
Budkuley, and Sidharth Jaggi. “New Results on AVCs with Omniscient and Myopic
Adversaries.” In 2022 IEEE International Symposium on Information Theory,
2022:2535–40. Institute of Electrical and Electronics Engineers, 2022. https://doi.org/10.1109/ISIT50566.2022.9834632.
ieee: A. K. Yadav, M. Alimohammadi, Y. Zhang, A. J. Budkuley, and S. Jaggi, “New
results on AVCs with omniscient and myopic adversaries,” in 2022 IEEE International
Symposium on Information Theory, Espoo, Finland, 2022, vol. 2022, pp. 2535–2540.
ista: 'Yadav AK, Alimohammadi M, Zhang Y, Budkuley AJ, Jaggi S. 2022. New results
on AVCs with omniscient and myopic adversaries. 2022 IEEE International Symposium
on Information Theory. ISIT: Internation Symposium on Information Theory vol.
2022, 2535–2540.'
mla: Yadav, Anuj Kumar, et al. “New Results on AVCs with Omniscient and Myopic Adversaries.”
2022 IEEE International Symposium on Information Theory, vol. 2022, Institute
of Electrical and Electronics Engineers, 2022, pp. 2535–40, doi:10.1109/ISIT50566.2022.9834632.
short: A.K. Yadav, M. Alimohammadi, Y. Zhang, A.J. Budkuley, S. Jaggi, in:, 2022
IEEE International Symposium on Information Theory, Institute of Electrical and
Electronics Engineers, 2022, pp. 2535–2540.
conference:
end_date: 2022-07-01
location: Espoo, Finland
name: 'ISIT: Internation Symposium on Information Theory'
start_date: 2022-06-26
date_created: 2022-09-04T22:02:06Z
date_published: 2022-08-03T00:00:00Z
date_updated: 2023-02-13T09:00:14Z
day: '03'
department:
- _id: MaMo
doi: 10.1109/ISIT50566.2022.9834632
intvolume: ' 2022'
language:
- iso: eng
month: '08'
oa_version: None
page: 2535-2540
publication: 2022 IEEE International Symposium on Information Theory
publication_identifier:
isbn:
- '9781665421591'
issn:
- 2157-8095
publication_status: published
publisher: Institute of Electrical and Electronics Engineers
quality_controlled: '1'
scopus_import: '1'
status: public
title: New results on AVCs with omniscient and myopic adversaries
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2022
year: '2022'
...
---
_id: '12018'
abstract:
- lang: eng
text: We study the problem of characterizing the maximal rates of list decoding
in Euclidean spaces for finite list sizes. For any positive integer L ≥ 2 and
real N > 0, we say that a subset C⊂Rn is an (N,L – 1)-multiple packing or an (N,L–
1)-list decodable code if every Euclidean ball of radius nN−−−√ in ℝ n contains
no more than L − 1 points of C. We study this problem with and without ℓ 2 norm
constraints on C, and derive the best-known lower bounds on the maximal rate for
(N,L−1) multiple packing. Our bounds are obtained via error exponents for list
decoding over Additive White Gaussian Noise (AWGN) channels. We establish a curious
inequality which relates the error exponent, a quantity of average-case nature,
to the list-decoding radius, a quantity of worst-case nature. We derive various
bounds on the error exponent for list decoding in both bounded and unbounded settings
which could be of independent interest beyond multiple packing.
article_processing_charge: No
author:
- first_name: Yihan
full_name: Zhang, Yihan
id: 2ce5da42-b2ea-11eb-bba5-9f264e9d002c
last_name: Zhang
- first_name: Shashank
full_name: Vatedka, Shashank
last_name: Vatedka
citation:
ama: 'Zhang Y, Vatedka S. Lower bounds on list decoding capacity using error exponents.
In: 2022 IEEE International Symposium on Information Theory. Vol 2022.
Institute of Electrical and Electronics Engineers; 2022:1324-1329. doi:10.1109/ISIT50566.2022.9834815'
apa: 'Zhang, Y., & Vatedka, S. (2022). Lower bounds on list decoding capacity
using error exponents. In 2022 IEEE International Symposium on Information
Theory (Vol. 2022, pp. 1324–1329). Espoo, Finland: Institute of Electrical
and Electronics Engineers. https://doi.org/10.1109/ISIT50566.2022.9834815'
chicago: Zhang, Yihan, and Shashank Vatedka. “Lower Bounds on List Decoding Capacity
Using Error Exponents.” In 2022 IEEE International Symposium on Information
Theory, 2022:1324–29. Institute of Electrical and Electronics Engineers, 2022.
https://doi.org/10.1109/ISIT50566.2022.9834815.
ieee: Y. Zhang and S. Vatedka, “Lower bounds on list decoding capacity using error
exponents,” in 2022 IEEE International Symposium on Information Theory,
Espoo, Finland, 2022, vol. 2022, pp. 1324–1329.
ista: 'Zhang Y, Vatedka S. 2022. Lower bounds on list decoding capacity using error
exponents. 2022 IEEE International Symposium on Information Theory. ISIT: Internation
Symposium on Information Theory vol. 2022, 1324–1329.'
mla: Zhang, Yihan, and Shashank Vatedka. “Lower Bounds on List Decoding Capacity
Using Error Exponents.” 2022 IEEE International Symposium on Information Theory,
vol. 2022, Institute of Electrical and Electronics Engineers, 2022, pp. 1324–29,
doi:10.1109/ISIT50566.2022.9834815.
short: Y. Zhang, S. Vatedka, in:, 2022 IEEE International Symposium on Information
Theory, Institute of Electrical and Electronics Engineers, 2022, pp. 1324–1329.
conference:
end_date: 2022-07-01
location: Espoo, Finland
name: 'ISIT: Internation Symposium on Information Theory'
start_date: 2022-06-26
date_created: 2022-09-04T22:02:06Z
date_published: 2022-08-03T00:00:00Z
date_updated: 2023-02-13T09:02:06Z
day: '03'
department:
- _id: MaMo
doi: 10.1109/ISIT50566.2022.9834815
intvolume: ' 2022'
language:
- iso: eng
month: '08'
oa_version: None
page: 1324-1329
publication: 2022 IEEE International Symposium on Information Theory
publication_identifier:
isbn:
- '9781665421591'
issn:
- 2157-8095
publication_status: published
publisher: Institute of Electrical and Electronics Engineers
quality_controlled: '1'
scopus_import: '1'
status: public
title: Lower bounds on list decoding capacity using error exponents
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2022
year: '2022'
...
---
_id: '12019'
abstract:
- lang: eng
text: This paper studies combinatorial properties of codes for the Z-channel. A
Z-channel with error fraction τ takes as input a length-n binary codeword and
injects in an adversarial manner up to nτ asymmetric errors, i.e., errors that
only zero out bits but do not flip 0’s to 1’s. It is known that the largest (L
− 1)-list-decodable code for the Z-channel with error fraction τ has exponential
(in n) size if τ is less than a critical value that we call the Plotkin point
and has constant size if τ is larger than the threshold. The (L−1)-list-decoding
Plotkin point is known to be L−1L−1−L−LL−1. In this paper, we show that the largest
(L−1)-list-decodable code ε-above the Plotkin point has size Θ L (ε −3/2 ) for
any L − 1 ≥ 1.
article_processing_charge: No
author:
- first_name: Nikita
full_name: Polyanskii, Nikita
last_name: Polyanskii
- first_name: Yihan
full_name: Zhang, Yihan
id: 2ce5da42-b2ea-11eb-bba5-9f264e9d002c
last_name: Zhang
citation:
ama: 'Polyanskii N, Zhang Y. List-decodable zero-rate codes for the Z-channel. In:
2022 IEEE International Symposium on Information Theory. Vol 2022. Institute
of Electrical and Electronics Engineers; 2022:2553-2558. doi:10.1109/ISIT50566.2022.9834829'
apa: 'Polyanskii, N., & Zhang, Y. (2022). List-decodable zero-rate codes for
the Z-channel. In 2022 IEEE International Symposium on Information Theory
(Vol. 2022, pp. 2553–2558). Espoo, Finland: Institute of Electrical and Electronics
Engineers. https://doi.org/10.1109/ISIT50566.2022.9834829'
chicago: Polyanskii, Nikita, and Yihan Zhang. “List-Decodable Zero-Rate Codes for
the Z-Channel.” In 2022 IEEE International Symposium on Information Theory,
2022:2553–58. Institute of Electrical and Electronics Engineers, 2022. https://doi.org/10.1109/ISIT50566.2022.9834829.
ieee: N. Polyanskii and Y. Zhang, “List-decodable zero-rate codes for the Z-channel,”
in 2022 IEEE International Symposium on Information Theory, Espoo, Finland,
2022, vol. 2022, pp. 2553–2558.
ista: 'Polyanskii N, Zhang Y. 2022. List-decodable zero-rate codes for the Z-channel.
2022 IEEE International Symposium on Information Theory. ISIT: Internation Symposium
on Information Theory vol. 2022, 2553–2558.'
mla: Polyanskii, Nikita, and Yihan Zhang. “List-Decodable Zero-Rate Codes for the
Z-Channel.” 2022 IEEE International Symposium on Information Theory, vol.
2022, Institute of Electrical and Electronics Engineers, 2022, pp. 2553–58, doi:10.1109/ISIT50566.2022.9834829.
short: N. Polyanskii, Y. Zhang, in:, 2022 IEEE International Symposium on Information
Theory, Institute of Electrical and Electronics Engineers, 2022, pp. 2553–2558.
conference:
end_date: 2022-07-01
location: Espoo, Finland
name: 'ISIT: Internation Symposium on Information Theory'
start_date: 2022-06-26
date_created: 2022-09-04T22:02:07Z
date_published: 2022-08-03T00:00:00Z
date_updated: 2023-02-13T09:02:18Z
day: '03'
department:
- _id: MaMo
doi: 10.1109/ISIT50566.2022.9834829
intvolume: ' 2022'
language:
- iso: eng
month: '08'
oa_version: None
page: 2553-2558
publication: 2022 IEEE International Symposium on Information Theory
publication_identifier:
isbn:
- '9781665421591'
issn:
- 2157-8095
publication_status: published
publisher: Institute of Electrical and Electronics Engineers
quality_controlled: '1'
scopus_import: '1'
status: public
title: List-decodable zero-rate codes for the Z-channel
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2022
year: '2022'
...
---
_id: '12051'
abstract:
- lang: eng
text: Transcription of the ribosomal RNA precursor by RNA polymerase (Pol) I is
a major determinant of cellular growth, and dysregulation is observed in many
cancer types. Here, we present the purification of human Pol I from cells carrying
a genomic GFP fusion on the largest subunit allowing the structural and functional
analysis of the enzyme across species. In contrast to yeast, human Pol I carries
a single-subunit stalk, and in vitro transcription indicates a reduced proofreading
activity. Determination of the human Pol I cryo-EM reconstruction in a close-to-native
state rationalizes the effects of disease-associated mutations and uncovers an
additional domain that is built into the sequence of Pol I subunit RPA1. This
“dock II” domain resembles a truncated HMG box incapable of DNA binding which
may serve as a downstream transcription factor–binding platform in metazoans.
Biochemical analysis, in situ modelling, and ChIP data indicate that Topoisomerase
2a can be recruited to Pol I via the domain and cooperates with the HMG box domain–containing
factor UBF. These adaptations of the metazoan Pol I transcription system may allow
efficient release of positive DNA supercoils accumulating downstream of the transcription
bubble.
acknowledgement: "The authors especially thank Philip Gunkel for his contribution.
We thank all\r\npast and present members of the Engel lab, Achim Griesenbeck, Colyn
Crane-\r\nRobinson, Christophe Lotz, Marlene Vayssieres, Klaus Grasser, Herbert
Tschochner, and Philipp Milkereit for help and discussion; Gerhard Lehmann and Nobert
Eichner for IT support; Joost Zomerdijk for UBF-constructs, Volker Cordes for the
Hela P2 cell line; Remco Sprangers for shared cell culture; Dina Grohmann and the
Archaea Center for fermentation; and Thomas\r\nDresselhaus for access to fluorescence
microscopes. This work was in part supported by the Emmy-Noether Programm (DFG grant
no. EN 1204/1-1 to C Engel) of the German Research Council and Collaborative Research
Center 960 (TP-A8 to C Engel)."
article_number: e202201568
article_processing_charge: No
article_type: original
author:
- first_name: Julia L
full_name: Daiß, Julia L
last_name: Daiß
- first_name: Michael
full_name: Pilsl, Michael
last_name: Pilsl
- first_name: Kristina
full_name: Straub, Kristina
last_name: Straub
- first_name: Andrea
full_name: Bleckmann, Andrea
last_name: Bleckmann
- first_name: Mona
full_name: Höcherl, Mona
last_name: Höcherl
- first_name: Florian B
full_name: Heiss, Florian B
last_name: Heiss
- first_name: Guillermo
full_name: Abascal-Palacios, Guillermo
last_name: Abascal-Palacios
- first_name: Ewan P
full_name: Ramsay, Ewan P
last_name: Ramsay
- first_name: Katarina
full_name: Tluckova, Katarina
id: 4AC7D980-F248-11E8-B48F-1D18A9856A87
last_name: Tluckova
- first_name: Jean-Clement
full_name: Mars, Jean-Clement
last_name: Mars
- first_name: Torben
full_name: Fürtges, Torben
last_name: Fürtges
- first_name: Astrid
full_name: Bruckmann, Astrid
last_name: Bruckmann
- first_name: Till
full_name: Rudack, Till
last_name: Rudack
- first_name: Carrie A
full_name: Bernecky, Carrie A
id: 2CB9DFE2-F248-11E8-B48F-1D18A9856A87
last_name: Bernecky
orcid: 0000-0003-0893-7036
- first_name: Valérie
full_name: Lamour, Valérie
last_name: Lamour
- first_name: Konstantin
full_name: Panov, Konstantin
last_name: Panov
- first_name: Alessandro
full_name: Vannini, Alessandro
last_name: Vannini
- first_name: Tom
full_name: Moss, Tom
last_name: Moss
- first_name: Christoph
full_name: Engel, Christoph
last_name: Engel
citation:
ama: Daiß JL, Pilsl M, Straub K, et al. The human RNA polymerase I structure reveals
an HMG-like docking domain specific to metazoans. Life Science Alliance.
2022;5(11). doi:10.26508/lsa.202201568
apa: Daiß, J. L., Pilsl, M., Straub, K., Bleckmann, A., Höcherl, M., Heiss, F. B.,
… Engel, C. (2022). The human RNA polymerase I structure reveals an HMG-like docking
domain specific to metazoans. Life Science Alliance. Life Science Alliance.
https://doi.org/10.26508/lsa.202201568
chicago: Daiß, Julia L, Michael Pilsl, Kristina Straub, Andrea Bleckmann, Mona Höcherl,
Florian B Heiss, Guillermo Abascal-Palacios, et al. “The Human RNA Polymerase
I Structure Reveals an HMG-like Docking Domain Specific to Metazoans.” Life
Science Alliance. Life Science Alliance, 2022. https://doi.org/10.26508/lsa.202201568.
ieee: J. L. Daiß et al., “The human RNA polymerase I structure reveals an
HMG-like docking domain specific to metazoans,” Life Science Alliance,
vol. 5, no. 11. Life Science Alliance, 2022.
ista: Daiß JL, Pilsl M, Straub K, Bleckmann A, Höcherl M, Heiss FB, Abascal-Palacios
G, Ramsay EP, Tluckova K, Mars J-C, Fürtges T, Bruckmann A, Rudack T, Bernecky
C, Lamour V, Panov K, Vannini A, Moss T, Engel C. 2022. The human RNA polymerase
I structure reveals an HMG-like docking domain specific to metazoans. Life Science
Alliance. 5(11), e202201568.
mla: Daiß, Julia L., et al. “The Human RNA Polymerase I Structure Reveals an HMG-like
Docking Domain Specific to Metazoans.” Life Science Alliance, vol. 5, no.
11, e202201568, Life Science Alliance, 2022, doi:10.26508/lsa.202201568.
short: J.L. Daiß, M. Pilsl, K. Straub, A. Bleckmann, M. Höcherl, F.B. Heiss, G.
Abascal-Palacios, E.P. Ramsay, K. Tluckova, J.-C. Mars, T. Fürtges, A. Bruckmann,
T. Rudack, C. Bernecky, V. Lamour, K. Panov, A. Vannini, T. Moss, C. Engel, Life
Science Alliance 5 (2022).
date_created: 2022-09-06T18:45:23Z
date_published: 2022-09-01T00:00:00Z
date_updated: 2023-08-03T13:39:36Z
day: '01'
ddc:
- '570'
department:
- _id: CaBe
doi: 10.26508/lsa.202201568
external_id:
isi:
- '000972702600001'
file:
- access_level: open_access
checksum: 4201d876a3e5e8b65e319d03300014ad
content_type: application/pdf
creator: dernst
date_created: 2022-09-08T06:41:14Z
date_updated: 2022-09-08T06:41:14Z
file_id: '12062'
file_name: 2022_LifeScienceAlliance_Daiss.pdf
file_size: 3183129
relation: main_file
success: 1
file_date_updated: 2022-09-08T06:41:14Z
has_accepted_license: '1'
intvolume: ' 5'
isi: 1
issue: '11'
keyword:
- Health
- Toxicology and Mutagenesis
- Plant Science
- Biochemistry
- Genetics and Molecular Biology (miscellaneous)
- Ecology
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '09'
oa: 1
oa_version: Published Version
publication: Life Science Alliance
publication_identifier:
issn:
- 2575-1077
publication_status: published
publisher: Life Science Alliance
quality_controlled: '1'
status: public
title: The human RNA polymerase I structure reveals an HMG-like docking domain specific
to metazoans
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 5
year: '2022'
...
---
_id: '12052'
abstract:
- lang: eng
text: Directionality in the intercellular transport of the plant hormone auxin is
determined by polar plasma membrane localization of PIN-FORMED (PIN) auxin transport
proteins. However, apart from PIN phosphorylation at conserved motifs, no further
determinants explicitly controlling polar PIN sorting decisions have been identified.
Here we present Arabidopsis WAVY GROWTH 3 (WAV3) and closely related RING-finger
E3 ubiquitin ligases, whose loss-of-function mutants show a striking apical-to-basal
polarity switch in PIN2 localization in root meristem cells. WAV3 E3 ligases function
as essential determinants for PIN polarity, acting independently from PINOID/WAG-dependent
PIN phosphorylation. They antagonize ectopic deposition of de novo synthesized
PIN proteins already immediately following completion of cell division, presumably
via preventing PIN sorting into basal, ARF GEF-mediated trafficking. Our findings
reveal an involvement of E3 ligases in the selective targeting of apically localized
PINs in higher plants.
acknowledgement: We would like to thank Tatsuo Sakai, Marcus Heisler, Toru Fujiwara,
Lucia Strader, Christian Hardtke, Malcolm Bennett, Claus Schwechheimer, Gerd Jürgens
and Remko Offringa for sharing published materials and Alba Grau Gimeno for support.
We are greatly indebted to Bert de Rybel for supporting N.K. and M.G. to work on
the final stages of manuscript preparation as postdocs in his laboratory. A full-length
SOR1 cDNA clone (J090099M14) was obtained from the National Agriculture and Food
Research Organization (NARO, Japan). Support by the Multiscale Imaging Core Facility
at the BOKU is greatly acknowledged. This work has been supported by grants from
the Austrian Science Fund (FWF P25931-B16; P31493-B25 to Christian Luschnig; I3630-B25
to Jiří Friml; P30850-B32 to Barbara Korbei) and from the Swiss National Funds (31003A-165877/1
to Markus Geisler) and the European Union’s Horizon 2020 research and innovation
program (Marie Skłodowska-Curie grant agreement No 885979 to Matouš Glanc).
article_number: '5147'
article_processing_charge: No
article_type: original
author:
- first_name: N
full_name: Konstantinova, N
last_name: Konstantinova
- first_name: Lukas
full_name: Hörmayer, Lukas
id: 2EEE7A2A-F248-11E8-B48F-1D18A9856A87
last_name: Hörmayer
- first_name: Matous
full_name: Glanc, Matous
id: 1AE1EA24-02D0-11E9-9BAA-DAF4881429F2
last_name: Glanc
orcid: 0000-0003-0619-7783
- first_name: R
full_name: Keshkeih, R
last_name: Keshkeih
- first_name: Shutang
full_name: Tan, Shutang
id: 2DE75584-F248-11E8-B48F-1D18A9856A87
last_name: Tan
orcid: 0000-0002-0471-8285
- first_name: M
full_name: Di Donato, M
last_name: Di Donato
- first_name: K
full_name: Retzer, K
last_name: Retzer
- first_name: J
full_name: Moulinier-Anzola, J
last_name: Moulinier-Anzola
- first_name: M
full_name: Schwihla, M
last_name: Schwihla
- first_name: B
full_name: Korbei, B
last_name: Korbei
- first_name: M
full_name: Geisler, M
last_name: Geisler
- first_name: Jiří
full_name: Friml, Jiří
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: C
full_name: Luschnig, C
last_name: Luschnig
citation:
ama: Konstantinova N, Hörmayer L, Glanc M, et al. WAVY GROWTH Arabidopsis E3 ubiquitin
ligases affect apical PIN sorting decisions. Nature Communications. 2022;13.
doi:10.1038/s41467-022-32888-8
apa: Konstantinova, N., Hörmayer, L., Glanc, M., Keshkeih, R., Tan, S., Di Donato,
M., … Luschnig, C. (2022). WAVY GROWTH Arabidopsis E3 ubiquitin ligases affect
apical PIN sorting decisions. Nature Communications. Springer Nature. https://doi.org/10.1038/s41467-022-32888-8
chicago: Konstantinova, N, Lukas Hörmayer, Matous Glanc, R Keshkeih, Shutang Tan,
M Di Donato, K Retzer, et al. “WAVY GROWTH Arabidopsis E3 Ubiquitin Ligases Affect
Apical PIN Sorting Decisions.” Nature Communications. Springer Nature,
2022. https://doi.org/10.1038/s41467-022-32888-8.
ieee: N. Konstantinova et al., “WAVY GROWTH Arabidopsis E3 ubiquitin ligases
affect apical PIN sorting decisions,” Nature Communications, vol. 13. Springer
Nature, 2022.
ista: Konstantinova N, Hörmayer L, Glanc M, Keshkeih R, Tan S, Di Donato M, Retzer
K, Moulinier-Anzola J, Schwihla M, Korbei B, Geisler M, Friml J, Luschnig C. 2022.
WAVY GROWTH Arabidopsis E3 ubiquitin ligases affect apical PIN sorting decisions.
Nature Communications. 13, 5147.
mla: Konstantinova, N., et al. “WAVY GROWTH Arabidopsis E3 Ubiquitin Ligases Affect
Apical PIN Sorting Decisions.” Nature Communications, vol. 13, 5147, Springer
Nature, 2022, doi:10.1038/s41467-022-32888-8.
short: N. Konstantinova, L. Hörmayer, M. Glanc, R. Keshkeih, S. Tan, M. Di Donato,
K. Retzer, J. Moulinier-Anzola, M. Schwihla, B. Korbei, M. Geisler, J. Friml,
C. Luschnig, Nature Communications 13 (2022).
date_created: 2022-09-07T14:19:26Z
date_published: 2022-09-01T00:00:00Z
date_updated: 2023-08-03T13:40:32Z
day: '01'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1038/s41467-022-32888-8
external_id:
isi:
- '000848744900004'
pmid:
- '36050482'
file:
- access_level: open_access
checksum: 43336758c89cd6c045839089af070afe
content_type: application/pdf
creator: dernst
date_created: 2022-09-08T07:46:16Z
date_updated: 2022-09-08T07:46:16Z
file_id: '12063'
file_name: 2022_NatureCommunications_Konstantinova.pdf
file_size: 6678579
relation: main_file
success: 1
file_date_updated: 2022-09-08T07:46:16Z
has_accepted_license: '1'
intvolume: ' 13'
isi: 1
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 26538374-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: I03630
name: Molecular mechanisms of endocytic cargo recognition in plants
publication: Nature Communications
publication_identifier:
issn:
- 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
link:
- relation: erratum
url: https://doi.org/10.1038/s41467-022-33198-9
status: public
title: WAVY GROWTH Arabidopsis E3 ubiquitin ligases affect apical PIN sorting decisions
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 13
year: '2022'
...
---
_id: '12053'
abstract:
- lang: eng
text: Strigolactones (SLs) are a class of phytohormones that regulate plant shoot
branching and adventitious root development. However, little is known regarding
the role of SLs in controlling the behavior of the smallest unit of the organism,
the single cell. Here, taking advantage of a classic single-cell model offered
by the cotton (Gossypium hirsutum) fiber cell, we show that SLs, whose biosynthesis
is fine-tuned by gibberellins (GAs), positively regulate cell elongation and cell
wall thickness by promoting the biosynthesis of very-long-chain fatty acids (VLCFAs)
and cellulose, respectively. Furthermore, we identified two layers of transcription
factors (TFs) involved in the hierarchical regulation of this GA-SL crosstalk.
The top-layer TF GROWTH-REGULATING FACTOR 4 (GhGRF4) directly activates expression
of the SL biosynthetic gene DWARF27 (D27) to increase SL accumulation in fiber
cells and GAs induce GhGRF4 expression. SLs induce the expression of four second-layer
TF genes (GhNAC100-2, GhBLH51, GhGT2, and GhB9SHZ1), which transmit SL signals
downstream to two ketoacyl-CoA synthase genes (KCS) and three cellulose synthase
(CesA) genes by directly activating their transcription. Finally, the KCS and
CesA enzymes catalyze the biosynthesis of very long chain fatty acids and cellulose,
respectively, to regulate development of high-grade cotton fibers. In addition
to providing a theoretical basis for cotton fiber improvement, our results shed
light on SL signaling in plant development at the single-cell level.
acknowledgement: This work was supported by the National Natural Science Foundation
of China (32070549), Shaanxi Youth Entrusted Talent Program (20190205), Fundamental
Research Funds for the Central Universities (GK202002005 and GK202201017), Young
Elite Scientists Sponsorship Program by China Association for Science and Technology
(CAST) (2019-2021QNRC001), State Key Laboratory of Cotton Biology Open Fund (CB2020A12
and CB2021A21) and FWF Stand-alone Project (P29988).
article_processing_charge: No
article_type: original
author:
- first_name: Z
full_name: Tian, Z
last_name: Tian
- first_name: Yuzhou
full_name: Zhang, Yuzhou
id: 3B6137F2-F248-11E8-B48F-1D18A9856A87
last_name: Zhang
orcid: 0000-0003-2627-6956
- first_name: L
full_name: Zhu, L
last_name: Zhu
- first_name: B
full_name: Jiang, B
last_name: Jiang
- first_name: H
full_name: Wang, H
last_name: Wang
- first_name: R
full_name: Gao, R
last_name: Gao
- first_name: Jiří
full_name: Friml, Jiří
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: G
full_name: Xiao, G
last_name: Xiao
citation:
ama: Tian Z, Zhang Y, Zhu L, et al. Strigolactones act downstream of gibberellins
to regulate fiber cell elongation and cell wall thickness in cotton (Gossypium
hirsutum). The Plant Cell. 2022;34(12):4816-4839. doi:10.1093/plcell/koac270
apa: Tian, Z., Zhang, Y., Zhu, L., Jiang, B., Wang, H., Gao, R., … Xiao, G. (2022).
Strigolactones act downstream of gibberellins to regulate fiber cell elongation
and cell wall thickness in cotton (Gossypium hirsutum). The Plant Cell.
Oxford University Press. https://doi.org/10.1093/plcell/koac270
chicago: Tian, Z, Yuzhou Zhang, L Zhu, B Jiang, H Wang, R Gao, Jiří Friml, and G
Xiao. “Strigolactones Act Downstream of Gibberellins to Regulate Fiber Cell Elongation
and Cell Wall Thickness in Cotton (Gossypium Hirsutum).” The Plant Cell.
Oxford University Press, 2022. https://doi.org/10.1093/plcell/koac270.
ieee: Z. Tian et al., “Strigolactones act downstream of gibberellins to regulate
fiber cell elongation and cell wall thickness in cotton (Gossypium hirsutum),”
The Plant Cell, vol. 34, no. 12. Oxford University Press, pp. 4816–4839,
2022.
ista: Tian Z, Zhang Y, Zhu L, Jiang B, Wang H, Gao R, Friml J, Xiao G. 2022. Strigolactones
act downstream of gibberellins to regulate fiber cell elongation and cell wall
thickness in cotton (Gossypium hirsutum). The Plant Cell. 34(12), 4816–4839.
mla: Tian, Z., et al. “Strigolactones Act Downstream of Gibberellins to Regulate
Fiber Cell Elongation and Cell Wall Thickness in Cotton (Gossypium Hirsutum).”
The Plant Cell, vol. 34, no. 12, Oxford University Press, 2022, pp. 4816–39,
doi:10.1093/plcell/koac270.
short: Z. Tian, Y. Zhang, L. Zhu, B. Jiang, H. Wang, R. Gao, J. Friml, G. Xiao,
The Plant Cell 34 (2022) 4816–4839.
date_created: 2022-09-07T14:19:39Z
date_published: 2022-12-01T00:00:00Z
date_updated: 2023-08-03T13:41:06Z
day: '01'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1093/plcell/koac270
external_id:
isi:
- '000852753000001'
pmid:
- '36040191'
file:
- access_level: open_access
checksum: 1c606d9545f29dfca15235f69ad27b58
content_type: application/pdf
creator: dernst
date_created: 2023-01-20T08:29:12Z
date_updated: 2023-01-20T08:29:12Z
file_id: '12318'
file_name: 2022_PlantCell_Tian.pdf
file_size: 3282540
relation: main_file
success: 1
file_date_updated: 2023-01-20T08:29:12Z
has_accepted_license: '1'
intvolume: ' 34'
isi: 1
issue: '12'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '12'
oa: 1
oa_version: Published Version
page: 4816-4839
pmid: 1
project:
- _id: 262EF96E-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P29988
name: RNA-directed DNA methylation in plant development
publication: The Plant Cell
publication_identifier:
eissn:
- 1532-298X
issn:
- 1040-4651
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
related_material:
link:
- relation: erratum
url: https://doi.org/10.1093/plcell/koac342
scopus_import: '1'
status: public
title: Strigolactones act downstream of gibberellins to regulate fiber cell elongation
and cell wall thickness in cotton (Gossypium hirsutum)
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 34
year: '2022'
...
---
_id: '12054'
abstract:
- lang: eng
text: 'Polar auxin transport is unique to plants and coordinates their growth and
development1,2. The PIN-FORMED (PIN) auxin transporters exhibit highly asymmetrical
localizations at the plasma membrane and drive polar auxin transport3,4; however,
their structures and transport mechanisms remain largely unknown. Here, we report
three inward-facing conformation structures of Arabidopsis thaliana PIN1: the
apo state, bound to the natural auxin indole-3-acetic acid (IAA), and in complex
with the polar auxin transport inhibitor N-1-naphthylphthalamic acid (NPA). The
transmembrane domain of PIN1 shares a conserved NhaA fold5. In the substrate-bound
structure, IAA is coordinated by both hydrophobic stacking and hydrogen bonding.
NPA competes with IAA for the same site at the intracellular pocket, but with
a much higher affinity. These findings inform our understanding of the substrate
recognition and transport mechanisms of PINs and set up a framework for future
research on directional auxin transport, one of the most crucial processes underlying
plant development.'
acknowledgement: We thank the Cryo-EM Center of the University of Science and Technology
of China (USTC) and the Center for Biological Imaging (CBI), Institute of Biophysics,
Chinese Academy of Science, for the EM facility support; we thank B. Zhu, X. Huang
and all the other staff members for their technical support on cryo-EM data collection.
We thank J. Ren for his technical support with the transport assays and M. Seeger
for providing the sybody libraries. This work was supported by the Strategic Priority
Research Program of Chinese Academy of Sciences (XDB 37020204 to D.L. and XDB37020103
to Linfeng Sun), National Natural Science Foundation of China (82151215 and 31870726
to D.L., 31900885 to X.L., and 31870732 to Linfeng Sun), Natural Science Foundation
of Anhui Province (2008085MC90 to X.L. and 2008085J15 to Linfeng Sun), the Fundamental
Research Funds for the Central Universities (WK9100000031 to Linfeng Sun), and the
USTC Research Funds of the Double First-Class Initiative (YD9100002004 to Linfeng
Sun). Linfeng Sun is supported by an Outstanding Young Scholar Award from the Qiu
Shi Science and Technologies Foundation, and a Young Scholar Award from the Cyrus
Tang Foundation.
article_processing_charge: No
article_type: original
author:
- first_name: Z
full_name: Yang, Z
last_name: Yang
- first_name: J
full_name: Xia, J
last_name: Xia
- first_name: J
full_name: Hong, J
last_name: Hong
- first_name: C
full_name: Zhang, C
last_name: Zhang
- first_name: H
full_name: Wei, H
last_name: Wei
- first_name: W
full_name: Ying, W
last_name: Ying
- first_name: C
full_name: Sun, C
last_name: Sun
- first_name: L
full_name: Sun, L
last_name: Sun
- first_name: Y
full_name: Mao, Y
last_name: Mao
- first_name: Y
full_name: Gao, Y
last_name: Gao
- first_name: S
full_name: Tan, S
last_name: Tan
- first_name: Jiří
full_name: Friml, Jiří
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: D
full_name: Li, D
last_name: Li
- first_name: X
full_name: Liu, X
last_name: Liu
- first_name: L
full_name: Sun, L
last_name: Sun
citation:
ama: Yang Z, Xia J, Hong J, et al. Structural insights into auxin recognition and
efflux by Arabidopsis PIN1. Nature. 2022;609(7927):611-615. doi:10.1038/s41586-022-05143-9
apa: Yang, Z., Xia, J., Hong, J., Zhang, C., Wei, H., Ying, W., … Sun, L. (2022).
Structural insights into auxin recognition and efflux by Arabidopsis PIN1. Nature.
Springer Nature. https://doi.org/10.1038/s41586-022-05143-9
chicago: Yang, Z, J Xia, J Hong, C Zhang, H Wei, W Ying, C Sun, et al. “Structural
Insights into Auxin Recognition and Efflux by Arabidopsis PIN1.” Nature.
Springer Nature, 2022. https://doi.org/10.1038/s41586-022-05143-9.
ieee: Z. Yang et al., “Structural insights into auxin recognition and efflux
by Arabidopsis PIN1,” Nature, vol. 609, no. 7927. Springer Nature, pp.
611–615, 2022.
ista: Yang Z, Xia J, Hong J, Zhang C, Wei H, Ying W, Sun C, Sun L, Mao Y, Gao Y,
Tan S, Friml J, Li D, Liu X, Sun L. 2022. Structural insights into auxin recognition
and efflux by Arabidopsis PIN1. Nature. 609(7927), 611–615.
mla: Yang, Z., et al. “Structural Insights into Auxin Recognition and Efflux by
Arabidopsis PIN1.” Nature, vol. 609, no. 7927, Springer Nature, 2022, pp.
611–15, doi:10.1038/s41586-022-05143-9.
short: Z. Yang, J. Xia, J. Hong, C. Zhang, H. Wei, W. Ying, C. Sun, L. Sun, Y. Mao,
Y. Gao, S. Tan, J. Friml, D. Li, X. Liu, L. Sun, Nature 609 (2022) 611–615.
date_created: 2022-09-07T14:19:52Z
date_published: 2022-08-02T00:00:00Z
date_updated: 2023-08-03T13:41:44Z
day: '02'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1038/s41586-022-05143-9
external_id:
isi:
- '000848082900002'
pmid:
- '35917925'
file:
- access_level: open_access
checksum: 3136a585f8e1c7e73b5e1418b3d01898
content_type: application/pdf
creator: dernst
date_created: 2022-09-08T08:02:54Z
date_updated: 2022-09-08T08:02:54Z
file_id: '12064'
file_name: 2022_Nature_Yang.pdf
file_size: 32344580
relation: main_file
success: 1
file_date_updated: 2022-09-08T08:02:54Z
has_accepted_license: '1'
intvolume: ' 609'
isi: 1
issue: '7927'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: 611-615
pmid: 1
publication: Nature
publication_identifier:
eissn:
- 1476-4687
issn:
- 0028-0836
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Structural insights into auxin recognition and efflux by Arabidopsis PIN1
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 609
year: '2022'
...
---
_id: '12065'
abstract:
- lang: eng
text: Capacity, rate performance, and cycle life of aprotic Li–O2 batteries critically
depend on reversible electrodeposition of Li2O2. Current understanding states
surface-adsorbed versus solvated LiO2 controls Li2O2 growth as surface film or
as large particles. Herein, we show that Li2O2 forms across a wide range of electrolytes,
carbons, and current densities as particles via solution-mediated LiO2 disproportionation,
bringing into question the prevalence of any surface growth under practical conditions.
We describe a unified O2 reduction mechanism, which can explain all found capacity
relations and Li2O2 morphologies with exclusive solution discharge. Determining
particle morphology and achievable capacities are species mobilities, true areal
rate, and the degree of LiO2 association in solution. Capacity is conclusively
limited by mass transport through the tortuous Li2O2 rather than electron transport
through a passivating Li2O2 film. Provided that species mobilities and surface
growth are high, high capacities are also achieved with weakly solvating electrolytes,
which were previously considered prototypical for low capacity via surface growth.
acknowledged_ssus:
- _id: EM-Fac
- _id: M-Shop
acknowledgement: S.A.F. and C.P. are indebted to the European Research Council (ERC)
under the European Union’s Horizon 2020 research and innovation program (Grant Agreement
No. 636069). This project has received funding from the European Union’s Horizon
2020 research and innovation program under the Marie Skłodowska-Curie Grant NanoEvolution,
Grant Agreement No. 894042. S.A.F. and S.M. are indebted to Institute of Science
and Technology Austria (ISTA) for support. This research was supported by the Scientific
Service Units of ISTA through resources provided by the Electron Microscopy Facility
and the Miba Machine Shop. C.P. thanks Vanessa Wood (ETH Zürich) for her continuing
support.
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Christian
full_name: Prehal, Christian
last_name: Prehal
- first_name: Soumyadip
full_name: Mondal, Soumyadip
id: d25d21ef-dc8d-11ea-abe3-ec4576307f48
last_name: Mondal
- first_name: Ludek
full_name: Lovicar, Ludek
id: 36DB3A20-F248-11E8-B48F-1D18A9856A87
last_name: Lovicar
- first_name: Stefan Alexander
full_name: Freunberger, Stefan Alexander
id: A8CA28E6-CE23-11E9-AD2D-EC27E6697425
last_name: Freunberger
orcid: 0000-0003-2902-5319
citation:
ama: Prehal C, Mondal S, Lovicar L, Freunberger SA. Exclusive solution discharge
in Li-O₂ batteries? ACS Energy Letters. 2022;7(9):3112-3119. doi:10.1021/acsenergylett.2c01711
apa: Prehal, C., Mondal, S., Lovicar, L., & Freunberger, S. A. (2022). Exclusive
solution discharge in Li-O₂ batteries? ACS Energy Letters. American Chemical
Society. https://doi.org/10.1021/acsenergylett.2c01711
chicago: Prehal, Christian, Soumyadip Mondal, Ludek Lovicar, and Stefan Alexander
Freunberger. “Exclusive Solution Discharge in Li-O₂ Batteries?” ACS Energy
Letters. American Chemical Society, 2022. https://doi.org/10.1021/acsenergylett.2c01711.
ieee: C. Prehal, S. Mondal, L. Lovicar, and S. A. Freunberger, “Exclusive solution
discharge in Li-O₂ batteries?,” ACS Energy Letters, vol. 7, no. 9. American
Chemical Society, pp. 3112–3119, 2022.
ista: Prehal C, Mondal S, Lovicar L, Freunberger SA. 2022. Exclusive solution discharge
in Li-O₂ batteries? ACS Energy Letters. 7(9), 3112–3119.
mla: Prehal, Christian, et al. “Exclusive Solution Discharge in Li-O₂ Batteries?”
ACS Energy Letters, vol. 7, no. 9, American Chemical Society, 2022, pp.
3112–19, doi:10.1021/acsenergylett.2c01711.
short: C. Prehal, S. Mondal, L. Lovicar, S.A. Freunberger, ACS Energy Letters 7
(2022) 3112–3119.
date_created: 2022-09-08T09:51:09Z
date_published: 2022-08-29T00:00:00Z
date_updated: 2023-08-03T13:47:56Z
day: '29'
ddc:
- '540'
department:
- _id: StFr
- _id: EM-Fac
doi: 10.1021/acsenergylett.2c01711
external_id:
isi:
- '000860787000001'
file:
- access_level: open_access
checksum: cf0bed3a2535c11d27244cd029dbc1d0
content_type: application/pdf
creator: dernst
date_created: 2023-01-20T08:43:51Z
date_updated: 2023-01-20T08:43:51Z
file_id: '12319'
file_name: 2022_ACSEnergyLetters_Prehal.pdf
file_size: 3827583
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success: 1
file_date_updated: 2023-01-20T08:43:51Z
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intvolume: ' 7'
isi: 1
issue: '9'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: 3112-3119
publication: ACS Energy Letters
publication_identifier:
eissn:
- 2380-8195
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Exclusive solution discharge in Li-O₂ batteries?
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 7
year: '2022'
...
---
_id: '12067'
abstract:
- lang: eng
text: We present a divergent strategy for the fluorination of phenylacetic acid
derivatives that is induced by a charge-transfer complex between Selectfluor and
4-(dimethylamino)pyridine. A comprehensive investigation of the conditions revealed
a critical role of the solvent on the reaction outcome. In the presence of water,
decarboxylative fluorination through a single-electron oxidation is dominant.
Non-aqueous conditions result in the clean formation of α-fluoro-α-arylcarboxylic
acids.
article_processing_charge: No
article_type: original
author:
- first_name: Amiera
full_name: Madani, Amiera
last_name: Madani
- first_name: Lucia
full_name: Anghileri, Lucia
last_name: Anghileri
- first_name: Matthias
full_name: Heydenreich, Matthias
last_name: Heydenreich
- first_name: Heiko M.
full_name: Möller, Heiko M.
last_name: Möller
- first_name: Bartholomäus
full_name: Pieber, Bartholomäus
id: 93e5e5b2-0da6-11ed-8a41-af589a024726
last_name: Pieber
orcid: 0000-0001-8689-388X
citation:
ama: Madani A, Anghileri L, Heydenreich M, Möller HM, Pieber B. Benzylic fluorination
induced by a charge-transfer complex with a solvent-dependent selectivity switch.
Organic Letters. 2022;24(29):5376–5380. doi:10.1021/acs.orglett.2c02050
apa: Madani, A., Anghileri, L., Heydenreich, M., Möller, H. M., & Pieber, B.
(2022). Benzylic fluorination induced by a charge-transfer complex with a solvent-dependent
selectivity switch. Organic Letters. American Chemical Society. https://doi.org/10.1021/acs.orglett.2c02050
chicago: Madani, Amiera, Lucia Anghileri, Matthias Heydenreich, Heiko M. Möller,
and Bartholomäus Pieber. “Benzylic Fluorination Induced by a Charge-Transfer Complex
with a Solvent-Dependent Selectivity Switch.” Organic Letters. American
Chemical Society, 2022. https://doi.org/10.1021/acs.orglett.2c02050.
ieee: A. Madani, L. Anghileri, M. Heydenreich, H. M. Möller, and B. Pieber, “Benzylic
fluorination induced by a charge-transfer complex with a solvent-dependent selectivity
switch,” Organic Letters, vol. 24, no. 29. American Chemical Society, pp.
5376–5380, 2022.
ista: Madani A, Anghileri L, Heydenreich M, Möller HM, Pieber B. 2022. Benzylic
fluorination induced by a charge-transfer complex with a solvent-dependent selectivity
switch. Organic Letters. 24(29), 5376–5380.
mla: Madani, Amiera, et al. “Benzylic Fluorination Induced by a Charge-Transfer
Complex with a Solvent-Dependent Selectivity Switch.” Organic Letters,
vol. 24, no. 29, American Chemical Society, 2022, pp. 5376–5380, doi:10.1021/acs.orglett.2c02050.
short: A. Madani, L. Anghileri, M. Heydenreich, H.M. Möller, B. Pieber, Organic
Letters 24 (2022) 5376–5380.
date_created: 2022-09-08T11:34:30Z
date_published: 2022-07-17T00:00:00Z
date_updated: 2023-05-08T08:39:34Z
day: '17'
doi: 10.1021/acs.orglett.2c02050
extern: '1'
intvolume: ' 24'
issue: '29'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.26434/chemrxiv-2022-mstv5
month: '07'
oa: 1
oa_version: Published Version
page: 5376–5380
publication: Organic Letters
publication_identifier:
eissn:
- 1523-7052
issn:
- 1523-7060
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Benzylic fluorination induced by a charge-transfer complex with a solvent-dependent
selectivity switch
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 24
year: '2022'
...
---
_id: '12072'
abstract:
- lang: eng
text: "In this thesis, we study two of the most important questions in Arithmetic
geometry: that of the existence and density of solutions to Diophantine equations.
In order for a Diophantine equation to have any solutions over the rational numbers,
it must have solutions everywhere locally, i.e., over R and over Qp for every
prime p. The converse, called the Hasse principle, is known to fail in general.
However, it is still a central question in Arithmetic geometry to determine for
which varieties the Hasse principle does hold. In this work, we establish the
Hasse principle for a wide new family of varieties of the form f(t) = NK/Q(x)
̸= 0, where f is a polynomial with integer coefficients and NK/Q denotes the norm\r\nform
associated to a number field K. Our results cover products of arbitrarily many
linear, quadratic or cubic factors, and generalise an argument of Irving [69],
which makes use of the beta sieve of Rosser and Iwaniec. We also demonstrate how
our main sieve results can be applied to treat new cases of a conjecture of Harpaz
and Wittenberg on locally split values of polynomials over number fields, and
discuss consequences for rational points in fibrations.\r\nIn the second question,
about the density of solutions, one defines a height function and seeks to estimate
asymptotically the number of points of height bounded by B as B → ∞. Traditionally,
one either counts rational points, or\r\nintegral points with respect to a suitable
model. However, in this thesis, we study an emerging area of interest in Arithmetic
geometry known as Campana points, which in some sense interpolate between rational
and integral points.\r\nMore precisely, we count the number of nonzero integers
z1, z2, z3 such that gcd(z1, z2, z3) = 1, and z1, z2, z3, z1 + z2 + z3 are all
squareful and bounded by B. Using the circle method, we obtain an asymptotic formula
which agrees in\r\nthe power of B and log B with a bold new generalisation of
Manin’s conjecture to the setting of Campana points, recently formulated by Pieropan,
Smeets, Tanimoto and Várilly-Alvarado [96]. However, in this thesis we also provide
the first known counterexamples to leading constant predicted by their conjecture. "
acknowledgement: I acknowledge the received funding from the European Union’s Horizon
2020 research and innovation programme under the Marie Sklodowska Curie Grant Agreement
No. 665385.
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Alec L
full_name: Shute, Alec L
id: 440EB050-F248-11E8-B48F-1D18A9856A87
last_name: Shute
orcid: 0000-0002-1812-2810
citation:
ama: 'Shute AL. Existence and density problems in Diophantine geometry: From norm
forms to Campana points. 2022. doi:10.15479/at:ista:12072'
apa: 'Shute, A. L. (2022). Existence and density problems in Diophantine geometry:
From norm forms to Campana points. Institute of Science and Technology Austria.
https://doi.org/10.15479/at:ista:12072'
chicago: 'Shute, Alec L. “Existence and Density Problems in Diophantine Geometry:
From Norm Forms to Campana Points.” Institute of Science and Technology Austria,
2022. https://doi.org/10.15479/at:ista:12072.'
ieee: 'A. L. Shute, “Existence and density problems in Diophantine geometry: From
norm forms to Campana points,” Institute of Science and Technology Austria, 2022.'
ista: 'Shute AL. 2022. Existence and density problems in Diophantine geometry: From
norm forms to Campana points. Institute of Science and Technology Austria.'
mla: 'Shute, Alec L. Existence and Density Problems in Diophantine Geometry:
From Norm Forms to Campana Points. Institute of Science and Technology Austria,
2022, doi:10.15479/at:ista:12072.'
short: 'A.L. Shute, Existence and Density Problems in Diophantine Geometry: From
Norm Forms to Campana Points, Institute of Science and Technology Austria, 2022.'
date_created: 2022-09-08T21:53:03Z
date_published: 2022-09-08T00:00:00Z
date_updated: 2023-02-21T16:37:35Z
day: '08'
ddc:
- '512'
degree_awarded: PhD
department:
- _id: GradSch
- _id: TiBr
doi: 10.15479/at:ista:12072
ec_funded: 1
file:
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content_type: application/pdf
creator: ashute
date_created: 2022-09-08T21:50:34Z
date_updated: 2022-09-08T21:50:34Z
file_id: '12073'
file_name: Thesis_final_draft.pdf
file_size: 1907386
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success: 1
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creator: ashute
date_created: 2022-09-08T21:50:42Z
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file_id: '12074'
file_name: athesis.tex
file_size: 495393
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creator: ashute
date_created: 2022-09-09T12:05:00Z
date_updated: 2022-09-12T11:24:21Z
file_id: '12078'
file_name: qfcjsfmtvtbfrjjvhdzrnqxfvgjvxtbf.zip
file_size: 944534
relation: source_file
file_date_updated: 2022-09-12T11:24:21Z
has_accepted_license: '1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-sa/4.0/
month: '09'
oa: 1
oa_version: Published Version
page: '208'
project:
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '665385'
name: International IST Doctoral Program
publication_identifier:
isbn:
- 978-3-99078-023-7
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
record:
- id: '12076'
relation: part_of_dissertation
status: public
- id: '12077'
relation: part_of_dissertation
status: public
status: public
supervisor:
- first_name: Timothy D
full_name: Browning, Timothy D
id: 35827D50-F248-11E8-B48F-1D18A9856A87
last_name: Browning
orcid: 0000-0002-8314-0177
title: 'Existence and density problems in Diophantine geometry: From norm forms to
Campana points'
tmp:
image: /images/cc_by_nc_sa.png
legal_code_url: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC
BY-NC-SA 4.0)
short: CC BY-NC-SA (4.0)
type: dissertation
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2022'
...
---
_id: '12079'
abstract:
- lang: eng
text: We extend the recent rigorous convergence result of Abels and Moser (SIAM
J Math Anal 54(1):114–172, 2022. https://doi.org/10.1137/21M1424925) concerning
convergence rates for solutions of the Allen–Cahn equation with a nonlinear Robin
boundary condition towards evolution by mean curvature flow with constant contact
angle. More precisely, in the present work we manage to remove the perturbative
assumption on the contact angle being close to 90∘. We establish under usual double-well
type assumptions on the potential and for a certain class of boundary energy densities
the sub-optimal convergence rate of order ε12 for general contact angles α∈(0,π).
For a very specific form of the boundary energy density, we even obtain from our
methods a sharp convergence rate of order ε; again for general contact angles
α∈(0,π). Our proof deviates from the popular strategy based on rigorous asymptotic
expansions and stability estimates for the linearized Allen–Cahn operator. Instead,
we follow the recent approach by Fischer et al. (SIAM J Math Anal 52(6):6222–6233,
2020. https://doi.org/10.1137/20M1322182), thus relying on a relative entropy
technique. We develop a careful adaptation of their approach in order to encode
the constant contact angle condition. In fact, we perform this task at the level
of the notion of gradient flow calibrations. This concept was recently introduced
in the context of weak-strong uniqueness for multiphase mean curvature flow by
Fischer et al. (arXiv:2003.05478v2).
acknowledgement: "This Project has received funding from the European Research Council
(ERC) under the European Union’s Horizon 2020 research and innovation programme
(Grant Agreement No 948819) , and from the Deutsche Forschungsgemeinschaft (DFG,
German Research Foundation) under Germany’s Excellence Strategy—EXC-2047/1 - 390685813.\r\nOpen
Access funding enabled and organized by Projekt DEAL."
article_number: '201'
article_processing_charge: No
article_type: original
author:
- first_name: Sebastian
full_name: Hensel, Sebastian
id: 4D23B7DA-F248-11E8-B48F-1D18A9856A87
last_name: Hensel
orcid: 0000-0001-7252-8072
- first_name: Maximilian
full_name: Moser, Maximilian
id: a60047a9-da77-11eb-85b4-c4dc385ebb8c
last_name: Moser
citation:
ama: 'Hensel S, Moser M. Convergence rates for the Allen–Cahn equation with boundary
contact energy: The non-perturbative regime. Calculus of Variations and Partial
Differential Equations. 2022;61(6). doi:10.1007/s00526-022-02307-3'
apa: 'Hensel, S., & Moser, M. (2022). Convergence rates for the Allen–Cahn equation
with boundary contact energy: The non-perturbative regime. Calculus of Variations
and Partial Differential Equations. Springer Nature. https://doi.org/10.1007/s00526-022-02307-3'
chicago: 'Hensel, Sebastian, and Maximilian Moser. “Convergence Rates for the Allen–Cahn
Equation with Boundary Contact Energy: The Non-Perturbative Regime.” Calculus
of Variations and Partial Differential Equations. Springer Nature, 2022. https://doi.org/10.1007/s00526-022-02307-3.'
ieee: 'S. Hensel and M. Moser, “Convergence rates for the Allen–Cahn equation with
boundary contact energy: The non-perturbative regime,” Calculus of Variations
and Partial Differential Equations, vol. 61, no. 6. Springer Nature, 2022.'
ista: 'Hensel S, Moser M. 2022. Convergence rates for the Allen–Cahn equation with
boundary contact energy: The non-perturbative regime. Calculus of Variations and
Partial Differential Equations. 61(6), 201.'
mla: 'Hensel, Sebastian, and Maximilian Moser. “Convergence Rates for the Allen–Cahn
Equation with Boundary Contact Energy: The Non-Perturbative Regime.” Calculus
of Variations and Partial Differential Equations, vol. 61, no. 6, 201, Springer
Nature, 2022, doi:10.1007/s00526-022-02307-3.'
short: S. Hensel, M. Moser, Calculus of Variations and Partial Differential Equations
61 (2022).
date_created: 2022-09-11T22:01:54Z
date_published: 2022-08-24T00:00:00Z
date_updated: 2023-08-03T13:48:30Z
day: '24'
ddc:
- '510'
department:
- _id: JuFi
doi: 10.1007/s00526-022-02307-3
ec_funded: 1
external_id:
isi:
- '000844247300008'
file:
- access_level: open_access
checksum: b2da020ce50440080feedabeab5b09c4
content_type: application/pdf
creator: dernst
date_created: 2023-01-20T08:56:01Z
date_updated: 2023-01-20T08:56:01Z
file_id: '12320'
file_name: 2022_Calculus_Hensel.pdf
file_size: 1278493
relation: main_file
success: 1
file_date_updated: 2023-01-20T08:56:01Z
has_accepted_license: '1'
intvolume: ' 61'
isi: 1
issue: '6'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
project:
- _id: 0aa76401-070f-11eb-9043-b5bb049fa26d
call_identifier: H2020
grant_number: '948819'
name: Bridging Scales in Random Materials
publication: Calculus of Variations and Partial Differential Equations
publication_identifier:
eissn:
- 1432-0835
issn:
- 0944-2669
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Convergence rates for the Allen–Cahn equation with boundary contact energy:
The non-perturbative regime'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 61
year: '2022'
...
---
_id: '12080'
abstract:
- lang: eng
text: 'Endocytosis is a multistep process involving the sequential recruitment and
action of numerous proteins. This process can be divided into two phases: an early
phase, in which sites of endocytosis are formed, and a late phase in which clathrin-coated
vesicles are formed and internalized into the cytosol, but how these phases link
to each other remains unclear. In this study, we demonstrate that anchoring the
yeast Eps15-like protein Pan1p to the peroxisome triggers most of the events occurring
during the late phase at the peroxisome. At this ectopic location, Pan1p recruits
most proteins that function in the late phases—including actin nucleation promoting
factors—and then initiates actin polymerization. Pan1p also recruited Prk1 kinase
and actin depolymerizing factors, thereby triggering disassembly immediately after
actin assembly and inducing dissociation of endocytic proteins from the peroxisome.
These observations suggest that Pan1p is a key regulator for initiating, processing,
and completing the late phase of endocytosis.'
acknowledgement: 'This work was supported by JSPS KAKENHI GRANT #18K062291, and the
Takeda Science Foundation to J.Y. Toshima, as well as JSPS KAKENHI GRANT #19K065710,
the Uehara Memorial Foundation, and Life Science Foundation of JAPAN to J. Toshima.'
article_number: e202112138
article_processing_charge: No
article_type: original
author:
- first_name: Mariko
full_name: Enshoji, Mariko
last_name: Enshoji
- first_name: Yoshiko
full_name: Miyano, Yoshiko
last_name: Miyano
- first_name: Nao
full_name: Yoshida, Nao
last_name: Yoshida
- first_name: Makoto
full_name: Nagano, Makoto
last_name: Nagano
- first_name: Minami
full_name: Watanabe, Minami
last_name: Watanabe
- first_name: Mayumi
full_name: Kunihiro, Mayumi
last_name: Kunihiro
- first_name: Daria E
full_name: Siekhaus, Daria E
id: 3D224B9E-F248-11E8-B48F-1D18A9856A87
last_name: Siekhaus
orcid: 0000-0001-8323-8353
- first_name: Junko Y.
full_name: Toshima, Junko Y.
last_name: Toshima
- first_name: Jiro
full_name: Toshima, Jiro
last_name: Toshima
citation:
ama: Enshoji M, Miyano Y, Yoshida N, et al. Eps15/Pan1p is a master regulator of
the late stages of the endocytic pathway. Journal of Cell Biology. 2022;221(10).
doi:10.1083/jcb.202112138
apa: Enshoji, M., Miyano, Y., Yoshida, N., Nagano, M., Watanabe, M., Kunihiro, M.,
… Toshima, J. (2022). Eps15/Pan1p is a master regulator of the late stages of
the endocytic pathway. Journal of Cell Biology. Rockefeller University
Press. https://doi.org/10.1083/jcb.202112138
chicago: Enshoji, Mariko, Yoshiko Miyano, Nao Yoshida, Makoto Nagano, Minami Watanabe,
Mayumi Kunihiro, Daria E Siekhaus, Junko Y. Toshima, and Jiro Toshima. “Eps15/Pan1p
Is a Master Regulator of the Late Stages of the Endocytic Pathway.” Journal
of Cell Biology. Rockefeller University Press, 2022. https://doi.org/10.1083/jcb.202112138.
ieee: M. Enshoji et al., “Eps15/Pan1p is a master regulator of the late stages
of the endocytic pathway,” Journal of Cell Biology, vol. 221, no. 10. Rockefeller
University Press, 2022.
ista: Enshoji M, Miyano Y, Yoshida N, Nagano M, Watanabe M, Kunihiro M, Siekhaus
DE, Toshima JY, Toshima J. 2022. Eps15/Pan1p is a master regulator of the late
stages of the endocytic pathway. Journal of Cell Biology. 221(10), e202112138.
mla: Enshoji, Mariko, et al. “Eps15/Pan1p Is a Master Regulator of the Late Stages
of the Endocytic Pathway.” Journal of Cell Biology, vol. 221, no. 10, e202112138,
Rockefeller University Press, 2022, doi:10.1083/jcb.202112138.
short: M. Enshoji, Y. Miyano, N. Yoshida, M. Nagano, M. Watanabe, M. Kunihiro, D.E.
Siekhaus, J.Y. Toshima, J. Toshima, Journal of Cell Biology 221 (2022).
date_created: 2022-09-11T22:01:54Z
date_published: 2022-08-19T00:00:00Z
date_updated: 2023-08-03T13:49:07Z
day: '19'
ddc:
- '570'
department:
- _id: DaSi
doi: 10.1083/jcb.202112138
external_id:
isi:
- '000932770500001'
pmid:
- '35984332'
file:
- access_level: open_access
checksum: f2e581e66b5cdab9df81b56e850b3eaa
content_type: application/pdf
creator: dernst
date_created: 2023-01-20T09:32:53Z
date_updated: 2023-02-21T23:30:39Z
embargo: 2023-02-20
file_id: '12321'
file_name: 2022_JCB_Enshoji.pdf
file_size: 7816875
relation: main_file
file_date_updated: 2023-02-21T23:30:39Z
has_accepted_license: '1'
intvolume: ' 221'
isi: 1
issue: '10'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
pmid: 1
publication: Journal of Cell Biology
publication_identifier:
eissn:
- 1540-8140
issn:
- 0021-9525
publication_status: published
publisher: Rockefeller University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Eps15/Pan1p is a master regulator of the late stages of the endocytic pathway
tmp:
image: /images/cc_by_nc_sa.png
legal_code_url: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC
BY-NC-SA 4.0)
short: CC BY-NC-SA (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 221
year: '2022'
...
---
_id: '12081'
abstract:
- lang: eng
text: 'Selection accumulates information in the genome—it guides stochastically
evolving populations toward states (genotype frequencies) that would be unlikely
under neutrality. This can be quantified as the Kullback–Leibler (KL) divergence
between the actual distribution of genotype frequencies and the corresponding
neutral distribution. First, we show that this population-level information sets
an upper bound on the information at the level of genotype and phenotype, limiting
how precisely they can be specified by selection. Next, we study how the accumulation
and maintenance of information is limited by the cost of selection, measured as
the genetic load or the relative fitness variance, both of which we connect to
the control-theoretic KL cost of control. The information accumulation rate is
upper bounded by the population size times the cost of selection. This bound is
very general, and applies across models (Wright–Fisher, Moran, diffusion) and
to arbitrary forms of selection, mutation, and recombination. Finally, the cost
of maintaining information depends on how it is encoded: Specifying a single allele
out of two is expensive, but one bit encoded among many weakly specified loci
(as in a polygenic trait) is cheap.'
acknowledgement: We thank Ksenia Khudiakova, Wiktor Młynarski, Sean Stankowski, and
two anonymous reviewers for discussions and comments on the manuscript. G.T. and
M.H. acknowledge funding from the Human Frontier Science Program Grant RGP0032/2018.
N.B. acknowledges funding from ERC Grant 250152 “Information and Evolution.”
article_number: e2123152119
article_processing_charge: No
article_type: original
author:
- first_name: Michal
full_name: Hledik, Michal
id: 4171253A-F248-11E8-B48F-1D18A9856A87
last_name: Hledik
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: Gašper
full_name: Tkačik, Gašper
id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
last_name: Tkačik
orcid: '1'
citation:
ama: Hledik M, Barton NH, Tkačik G. Accumulation and maintenance of information
in evolution. Proceedings of the National Academy of Sciences. 2022;119(36).
doi:10.1073/pnas.2123152119
apa: Hledik, M., Barton, N. H., & Tkačik, G. (2022). Accumulation and maintenance
of information in evolution. Proceedings of the National Academy of Sciences.
Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.2123152119
chicago: Hledik, Michal, Nicholas H Barton, and Gašper Tkačik. “Accumulation and
Maintenance of Information in Evolution.” Proceedings of the National Academy
of Sciences. Proceedings of the National Academy of Sciences, 2022. https://doi.org/10.1073/pnas.2123152119.
ieee: M. Hledik, N. H. Barton, and G. Tkačik, “Accumulation and maintenance of information
in evolution,” Proceedings of the National Academy of Sciences, vol. 119,
no. 36. Proceedings of the National Academy of Sciences, 2022.
ista: Hledik M, Barton NH, Tkačik G. 2022. Accumulation and maintenance of information
in evolution. Proceedings of the National Academy of Sciences. 119(36), e2123152119.
mla: Hledik, Michal, et al. “Accumulation and Maintenance of Information in Evolution.”
Proceedings of the National Academy of Sciences, vol. 119, no. 36, e2123152119,
Proceedings of the National Academy of Sciences, 2022, doi:10.1073/pnas.2123152119.
short: M. Hledik, N.H. Barton, G. Tkačik, Proceedings of the National Academy of
Sciences 119 (2022).
date_created: 2022-09-11T22:01:55Z
date_published: 2022-08-29T00:00:00Z
date_updated: 2025-06-30T13:21:05Z
day: '29'
ddc:
- '570'
department:
- _id: NiBa
- _id: GaTk
doi: 10.1073/pnas.2123152119
ec_funded: 1
external_id:
isi:
- '000889278400014'
pmid:
- '36037343'
file:
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checksum: 6dec51f6567da9039982a571508a8e4d
content_type: application/pdf
creator: dernst
date_created: 2022-09-12T08:08:12Z
date_updated: 2022-09-12T08:08:12Z
file_id: '12091'
file_name: 2022_PNAS_Hledik.pdf
file_size: 2165752
relation: main_file
success: 1
file_date_updated: 2022-09-12T08:08:12Z
has_accepted_license: '1'
intvolume: ' 119'
isi: 1
issue: '36'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 25B07788-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '250152'
name: Limits to selection in biology and in evolutionary computation
- _id: 2665AAFE-B435-11E9-9278-68D0E5697425
grant_number: RGP0034/2018
name: Can evolution minimize spurious signaling crosstalk to reach optimal performance?
publication: Proceedings of the National Academy of Sciences
publication_identifier:
eissn:
- 1091-6490
issn:
- 0027-8424
publication_status: published
publisher: Proceedings of the National Academy of Sciences
quality_controlled: '1'
related_material:
record:
- id: '15020'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Accumulation and maintenance of information in evolution
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 119
year: '2022'
...
---
_id: '12082'
abstract:
- lang: eng
text: Proximity-dependent protein labeling provides a powerful in vivo strategy
to characterize the interactomes of specific proteins. We previously optimized
a proximity labeling protocol for Caenorhabditis elegans using the highly active
biotin ligase TurboID. A significant constraint on the sensitivity of TurboID
is the presence of abundant endogenously biotinylated proteins that take up bandwidth
in the mass spectrometer, notably carboxylases that use biotin as a cofactor.
In C. elegans, these comprise POD-2/acetyl-CoA carboxylase alpha, PCCA-1/propionyl-CoA
carboxylase alpha, PYC-1/pyruvate carboxylase, and MCCC-1/methylcrotonyl-CoA carboxylase
alpha. Here, we developed ways to remove these carboxylases prior to streptavidin
purification and mass spectrometry by engineering their corresponding genes to
add a C-terminal His10 tag. This allows us to deplete them from C. elegans lysates
using immobilized metal affinity chromatography. To demonstrate the method's efficacy,
we use it to expand the interactome map of the presynaptic active zone protein
ELKS-1. We identify many known active zone proteins, including UNC-10/RIM, SYD-2/liprin-alpha,
SAD-1/BRSK1, CLA-1/CLArinet, C16E9.2/Sentryn, as well as previously uncharacterized
potentially synaptic proteins such as the ortholog of human angiomotin, F59C12.3
and the uncharacterized protein R148.3. Our approach provides a quick and inexpensive
solution to a common contaminant problem in biotin-dependent proximity labeling.
The approach may be applicable to other model organisms and will enable deeper
and more complete analysis of interactors for proteins of interest.
acknowledged_ssus:
- _id: Bio
acknowledgement: "We thank de Bono laboratory members for helpful comments on the
article and the Mass Spec Facilities at IST Austria and Max Perutz Labs for invaluable
discussions and comments on how to optimize mass spec analyses of worm samples.
We are grateful to Ekaterina Lashmanova for designing the degron knock-in constructs
and preparing the injection mixes for CRISPR/Cas9-mediated genome editing. All LC–MS/MS
analyses were performed on instruments of the Vienna BioCenter Core Facilities instrument
pool.\r\nThis work was supported by a Wellcome Investigator Award (grant no.: 209504/Z/17/Z
) to M.d.B. and an ISTplus Fellowship to M.A. (Marie Sklodowska-Curie agreement
no.: 754411)."
article_number: '102343'
article_processing_charge: No
article_type: original
author:
- first_name: Murat
full_name: Artan, Murat
id: C407B586-6052-11E9-B3AE-7006E6697425
last_name: Artan
- first_name: Markus
full_name: Hartl, Markus
last_name: Hartl
- first_name: Weiqiang
full_name: Chen, Weiqiang
last_name: Chen
- first_name: Mario
full_name: De Bono, Mario
id: 4E3FF80E-F248-11E8-B48F-1D18A9856A87
last_name: De Bono
orcid: 0000-0001-8347-0443
citation:
ama: Artan M, Hartl M, Chen W, de Bono M. Depletion of endogenously biotinylated
carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in
Caenorhabditis elegans. Journal of Biological Chemistry. 2022;298(9). doi:10.1016/j.jbc.2022.102343
apa: Artan, M., Hartl, M., Chen, W., & de Bono, M. (2022). Depletion of endogenously
biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity
labeling in Caenorhabditis elegans. Journal of Biological Chemistry. Elsevier.
https://doi.org/10.1016/j.jbc.2022.102343
chicago: Artan, Murat, Markus Hartl, Weiqiang Chen, and Mario de Bono. “Depletion
of Endogenously Biotinylated Carboxylases Enhances the Sensitivity of TurboID-Mediated
Proximity Labeling in Caenorhabditis Elegans.” Journal of Biological Chemistry.
Elsevier, 2022. https://doi.org/10.1016/j.jbc.2022.102343.
ieee: M. Artan, M. Hartl, W. Chen, and M. de Bono, “Depletion of endogenously biotinylated
carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in
Caenorhabditis elegans,” Journal of Biological Chemistry, vol. 298, no.
9. Elsevier, 2022.
ista: Artan M, Hartl M, Chen W, de Bono M. 2022. Depletion of endogenously biotinylated
carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in
Caenorhabditis elegans. Journal of Biological Chemistry. 298(9), 102343.
mla: Artan, Murat, et al. “Depletion of Endogenously Biotinylated Carboxylases Enhances
the Sensitivity of TurboID-Mediated Proximity Labeling in Caenorhabditis Elegans.”
Journal of Biological Chemistry, vol. 298, no. 9, 102343, Elsevier, 2022,
doi:10.1016/j.jbc.2022.102343.
short: M. Artan, M. Hartl, W. Chen, M. de Bono, Journal of Biological Chemistry
298 (2022).
date_created: 2022-09-11T22:01:55Z
date_published: 2022-09-01T00:00:00Z
date_updated: 2023-08-03T13:56:46Z
day: '01'
ddc:
- '570'
department:
- _id: MaDe
doi: 10.1016/j.jbc.2022.102343
ec_funded: 1
external_id:
isi:
- '000884241800011'
pmid:
- '35933017'
file:
- access_level: open_access
checksum: e726c7b9315230e6710e0b1f1d1677e9
content_type: application/pdf
creator: dernst
date_created: 2022-09-12T08:14:50Z
date_updated: 2022-09-12T08:14:50Z
file_id: '12092'
file_name: 2022_JBC_Artan.pdf
file_size: 2101656
relation: main_file
success: 1
file_date_updated: 2022-09-12T08:14:50Z
has_accepted_license: '1'
intvolume: ' 298'
isi: 1
issue: '9'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 23870BE8-32DE-11EA-91FC-C7463DDC885E
grant_number: 209504/A/17/Z
name: Molecular mechanisms of neural circuit function
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: Journal of Biological Chemistry
publication_identifier:
eissn:
- 1083-351X
issn:
- 0021-9258
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Depletion of endogenously biotinylated carboxylases enhances the sensitivity
of TurboID-mediated proximity labeling in Caenorhabditis elegans
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 298
year: '2022'
...
---
_id: '12083'
abstract:
- lang: eng
text: We consider the many-body time evolution of weakly interacting bosons in the
mean field regime for initial coherent states. We show that bounded k-particle
operators, corresponding to dependent random variables, satisfy both a law of
large numbers and a central limit theorem.
acknowledgement: S.R. would like to thank Robert Seiringer and Benedikt Stufler for
helpful discussions. Funding from the European Union’s Horizon 2020 Research and
Innovation Program under the ERC grant (Grant Agreement No. 694227) and under the
Marie Skłodowska-Curie grant (Agreement No. 754411) is acknowledged.
article_number: '081902'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Simone Anna Elvira
full_name: Rademacher, Simone Anna Elvira
id: 856966FE-A408-11E9-977E-802DE6697425
last_name: Rademacher
orcid: 0000-0001-5059-4466
citation:
ama: Rademacher SAE. Dependent random variables in quantum dynamics. Journal
of Mathematical Physics. 2022;63(8). doi:10.1063/5.0086712
apa: Rademacher, S. A. E. (2022). Dependent random variables in quantum dynamics.
Journal of Mathematical Physics. AIP Publishing. https://doi.org/10.1063/5.0086712
chicago: Rademacher, Simone Anna Elvira. “Dependent Random Variables in Quantum
Dynamics.” Journal of Mathematical Physics. AIP Publishing, 2022. https://doi.org/10.1063/5.0086712.
ieee: S. A. E. Rademacher, “Dependent random variables in quantum dynamics,” Journal
of Mathematical Physics, vol. 63, no. 8. AIP Publishing, 2022.
ista: Rademacher SAE. 2022. Dependent random variables in quantum dynamics. Journal
of Mathematical Physics. 63(8), 081902.
mla: Rademacher, Simone Anna Elvira. “Dependent Random Variables in Quantum Dynamics.”
Journal of Mathematical Physics, vol. 63, no. 8, 081902, AIP Publishing,
2022, doi:10.1063/5.0086712.
short: S.A.E. Rademacher, Journal of Mathematical Physics 63 (2022).
date_created: 2022-09-11T22:01:56Z
date_published: 2022-08-25T00:00:00Z
date_updated: 2023-08-03T13:57:19Z
day: '25'
ddc:
- '510'
department:
- _id: RoSe
doi: 10.1063/5.0086712
ec_funded: 1
external_id:
arxiv:
- '2112.04817'
isi:
- '000844402500001'
file:
- access_level: open_access
checksum: e6fb0cf3f0327739c5e69a2cfc4020eb
content_type: application/pdf
creator: dernst
date_created: 2022-09-12T07:35:34Z
date_updated: 2022-09-12T07:35:34Z
file_id: '12089'
file_name: 2022_JourMathPhysics_Rademacher.pdf
file_size: 4552261
relation: main_file
success: 1
file_date_updated: 2022-09-12T07:35:34Z
has_accepted_license: '1'
intvolume: ' 63'
isi: 1
issue: '8'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
project:
- _id: 25C6DC12-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '694227'
name: Analysis of quantum many-body systems
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: Journal of Mathematical Physics
publication_identifier:
issn:
- 0022-2488
publication_status: published
publisher: AIP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: Dependent random variables in quantum dynamics
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 63
year: '2022'
...
---
_id: '12084'
abstract:
- lang: eng
text: Neuronal networks encode information through patterns of activity that define
the networks’ function. The neurons’ activity relies on specific connectivity
structures, yet the link between structure and function is not fully understood.
Here, we tackle this structure-function problem with a new conceptual approach.
Instead of manipulating the connectivity directly, we focus on upper triangular
matrices, which represent the network dynamics in a given orthonormal basis obtained
by the Schur decomposition. This abstraction allows us to independently manipulate
the eigenspectrum and feedforward structures of a connectivity matrix. Using this
method, we describe a diverse repertoire of non-normal transient amplification,
and to complement the analysis of the dynamical regimes, we quantify the geometry
of output trajectories through the effective rank of both the eigenvector and
the dynamics matrices. Counter-intuitively, we find that shrinking the eigenspectrum’s
imaginary distribution leads to highly amplifying regimes in linear and long-lasting
dynamics in nonlinear networks. We also find a trade-off between amplification
and dimensionality of neuronal dynamics, i.e., trajectories in neuronal state-space.
Networks that can amplify a large number of orthogonal initial conditions produce
neuronal trajectories that lie in the same subspace of the neuronal state-space.
Finally, we examine networks of excitatory and inhibitory neurons. We find that
the strength of global inhibition is directly linked with the amplitude of amplification,
such that weakening inhibitory weights also decreases amplification, and that
the eigenspectrum’s imaginary distribution grows with an increase in the ratio
between excitatory-to-inhibitory and excitatory-to-excitatory connectivity strengths.
Consequently, the strength of global inhibition reveals itself as a strong signature
for amplification and a potential control mechanism to switch dynamical regimes.
Our results shed a light on how biological networks, i.e., networks constrained
by Dale’s law, may be optimised for specific dynamical regimes.
acknowledgement: 'We thank Friedemann Zenke for his comments, especially on the effect
of the self loops on the spectrum. We also thank Ken Miller and Bill Podlaski for
helpful comments. This research was funded by a Wellcome Trust and Royal Society
Henry Dale Research Fellowship (WT100000; TPV), a Wellcome Senior Research Fellowship
(214316/Z/18/Z; GC, EJA, and TPV), and a Research Project Grant by the Leverhulme
Trust (RPG-2016-446; EJA and TPV). '
article_number: e1010365
article_processing_charge: No
article_type: original
author:
- first_name: Georgia
full_name: Christodoulou, Georgia
last_name: Christodoulou
- first_name: Tim P
full_name: Vogels, Tim P
id: CB6FF8D2-008F-11EA-8E08-2637E6697425
last_name: Vogels
orcid: 0000-0003-3295-6181
- first_name: Everton J.
full_name: Agnes, Everton J.
last_name: Agnes
citation:
ama: Christodoulou G, Vogels TP, Agnes EJ. Regimes and mechanisms of transient amplification
in abstract and biological neural networks. PLoS Computational Biology.
2022;18(8). doi:10.1371/journal.pcbi.1010365
apa: Christodoulou, G., Vogels, T. P., & Agnes, E. J. (2022). Regimes and mechanisms
of transient amplification in abstract and biological neural networks. PLoS
Computational Biology. Public Library of Science. https://doi.org/10.1371/journal.pcbi.1010365
chicago: Christodoulou, Georgia, Tim P Vogels, and Everton J. Agnes. “Regimes and
Mechanisms of Transient Amplification in Abstract and Biological Neural Networks.”
PLoS Computational Biology. Public Library of Science, 2022. https://doi.org/10.1371/journal.pcbi.1010365.
ieee: G. Christodoulou, T. P. Vogels, and E. J. Agnes, “Regimes and mechanisms of
transient amplification in abstract and biological neural networks,” PLoS Computational
Biology, vol. 18, no. 8. Public Library of Science, 2022.
ista: Christodoulou G, Vogels TP, Agnes EJ. 2022. Regimes and mechanisms of transient
amplification in abstract and biological neural networks. PLoS Computational Biology.
18(8), e1010365.
mla: Christodoulou, Georgia, et al. “Regimes and Mechanisms of Transient Amplification
in Abstract and Biological Neural Networks.” PLoS Computational Biology,
vol. 18, no. 8, e1010365, Public Library of Science, 2022, doi:10.1371/journal.pcbi.1010365.
short: G. Christodoulou, T.P. Vogels, E.J. Agnes, PLoS Computational Biology 18
(2022).
date_created: 2022-09-11T22:01:56Z
date_published: 2022-08-15T00:00:00Z
date_updated: 2023-08-03T14:06:29Z
day: '15'
ddc:
- '570'
department:
- _id: TiVo
doi: 10.1371/journal.pcbi.1010365
external_id:
isi:
- '000937227700001'
file:
- access_level: open_access
checksum: 8a81ab29f837991ee0ea770817c4a50e
content_type: application/pdf
creator: dernst
date_created: 2022-09-12T07:47:55Z
date_updated: 2022-09-12T07:47:55Z
file_id: '12090'
file_name: 2022_PLoSCompBio_Christodoulou.pdf
file_size: 2867337
relation: main_file
success: 1
file_date_updated: 2022-09-12T07:47:55Z
has_accepted_license: '1'
intvolume: ' 18'
isi: 1
issue: '8'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
project:
- _id: c084a126-5a5b-11eb-8a69-d75314a70a87
grant_number: 214316/Z/18/Z
name: What’s in a memory? Spatiotemporal dynamics in strongly coupled recurrent
neuronal networks.
publication: PLoS Computational Biology
publication_identifier:
eissn:
- 1553-7358
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Regimes and mechanisms of transient amplification in abstract and biological
neural networks
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 18
year: '2022'
...
---
_id: '12085'
abstract:
- lang: eng
text: Molecular catch bonds are ubiquitous in biology and essential for processes
like leucocyte extravasion1 and cellular mechanosensing2. Unlike normal (slip)
bonds, catch bonds strengthen under tension. The current paradigm is that this
feature provides ‘strength on demand3’, thus enabling cells to increase rigidity
under stress1,4,5,6. However, catch bonds are often weaker than slip bonds because
they have cryptic binding sites that are usually buried7,8. Here we show that
catch bonds render reconstituted cytoskeletal actin networks stronger than slip
bonds, even though the individual bonds are weaker. Simulations show that slip
bonds remain trapped in stress-free areas, whereas weak binding allows catch bonds
to mitigate crack initiation by moving to high-tension areas. This ‘dissociation
on demand’ explains how cells combine mechanical strength with the adaptability
required for shape change, and is relevant to diseases where catch bonding is
compromised7,9, including focal segmental glomerulosclerosis10 caused by the α-actinin-4
mutant studied here. We surmise that catch bonds are the key to create life-like
materials.
acknowledgement: 'We thank M. van Hecke and C. Alkemade for critical reading of the
manuscript. We thank P. R. ten Wolde, K. Storm, W. Ellenbroek, C. Broedersz, D.
Brueckner and M. Berger for fruitful discussions. We thank W. Brieher and V. Tang
from the University of Illinois for the kind gift of purified α-actinin-4 (WT and
the K255E point mutant) and their plasmids; M. Kuit-Vinkenoog and J. den Haan for
actin and further purification of α-actinin-4; A. Goutou and I. Isturiz-Petitjean
for co-sedimentation measurements and V. Sunderlíková for the design, mutagenesis,
cloning and purifying of the α-actinin-4 constructs used in the single-molecule
experiments. We gratefully acknowledge financial support from the following sources:
research program of the Netherlands Organization for Scientific Research (NWO) (S.J.T.,
A.R. and M.J.A.); ERC Starting Grant (335672-MINICELL) (G.H.K. and Y.M.). ‘BaSyC—Building
a Synthetic Cell’ Gravitation grant (024.003.019) of the Netherlands Ministry of
Education, Culture and Science (OCW) and the Netherlands Organisation for Scientific
Research (G.H.K. and L.B.); and support from the National Institutes of Health (1R01GM126256)
(T.K. and W.J.).'
article_processing_charge: No
article_type: original
author:
- first_name: Yuval
full_name: Mulla, Yuval
last_name: Mulla
- first_name: Mario
full_name: Avellaneda Sarrió, Mario
id: DC4BA84C-56E6-11EA-AD5D-348C3DDC885E
last_name: Avellaneda Sarrió
orcid: 0000-0001-6406-524X
- first_name: Antoine
full_name: Roland, Antoine
last_name: Roland
- first_name: Lucia
full_name: Baldauf, Lucia
last_name: Baldauf
- first_name: Wonyeong
full_name: Jung, Wonyeong
last_name: Jung
- first_name: Taeyoon
full_name: Kim, Taeyoon
last_name: Kim
- first_name: Sander J.
full_name: Tans, Sander J.
last_name: Tans
- first_name: Gijsje H.
full_name: Koenderink, Gijsje H.
last_name: Koenderink
citation:
ama: Mulla Y, Avellaneda Sarrió M, Roland A, et al. Weak catch bonds make strong
networks. Nature Materials. 2022;21(9):1019-1023. doi:10.1038/s41563-022-01288-0
apa: Mulla, Y., Avellaneda Sarrió, M., Roland, A., Baldauf, L., Jung, W., Kim, T.,
… Koenderink, G. H. (2022). Weak catch bonds make strong networks. Nature Materials.
Springer Nature. https://doi.org/10.1038/s41563-022-01288-0
chicago: Mulla, Yuval, Mario Avellaneda Sarrió, Antoine Roland, Lucia Baldauf, Wonyeong
Jung, Taeyoon Kim, Sander J. Tans, and Gijsje H. Koenderink. “Weak Catch Bonds
Make Strong Networks.” Nature Materials. Springer Nature, 2022. https://doi.org/10.1038/s41563-022-01288-0.
ieee: Y. Mulla et al., “Weak catch bonds make strong networks,” Nature
Materials, vol. 21, no. 9. Springer Nature, pp. 1019–1023, 2022.
ista: Mulla Y, Avellaneda Sarrió M, Roland A, Baldauf L, Jung W, Kim T, Tans SJ,
Koenderink GH. 2022. Weak catch bonds make strong networks. Nature Materials.
21(9), 1019–1023.
mla: Mulla, Yuval, et al. “Weak Catch Bonds Make Strong Networks.” Nature Materials,
vol. 21, no. 9, Springer Nature, 2022, pp. 1019–23, doi:10.1038/s41563-022-01288-0.
short: Y. Mulla, M. Avellaneda Sarrió, A. Roland, L. Baldauf, W. Jung, T. Kim, S.J.
Tans, G.H. Koenderink, Nature Materials 21 (2022) 1019–1023.
date_created: 2022-09-11T22:01:57Z
date_published: 2022-09-01T00:00:00Z
date_updated: 2023-08-03T14:08:47Z
day: '01'
department:
- _id: MiSi
doi: 10.1038/s41563-022-01288-0
external_id:
isi:
- '000844592000002'
pmid:
- '36008604'
intvolume: ' 21'
isi: 1
issue: '9'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1101/2020.07.27.219618
month: '09'
oa: 1
oa_version: Preprint
page: 1019-1023
pmid: 1
publication: Nature Materials
publication_identifier:
eissn:
- 1476-4660
issn:
- 1476-1122
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Weak catch bonds make strong networks
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 21
year: '2022'
...
---
_id: '12088'
abstract:
- lang: eng
text: We present a quantum-enabled microwave-telecom interface with bidirectional
conversion efficiencies up to 15% and added input noise quanta as low as 0.16.
Moreover, we observe evidence for electro-optic laser cooling and vacuum amplification.
article_number: FW4D.4
article_processing_charge: No
author:
- first_name: Rishabh
full_name: Sahu, Rishabh
id: 47D26E34-F248-11E8-B48F-1D18A9856A87
last_name: Sahu
orcid: 0000-0001-6264-2162
- first_name: William J
full_name: Hease, William J
id: 29705398-F248-11E8-B48F-1D18A9856A87
last_name: Hease
- first_name: Alfredo R
full_name: Rueda Sanchez, Alfredo R
id: 3B82B0F8-F248-11E8-B48F-1D18A9856A87
last_name: Rueda Sanchez
orcid: 0000-0001-6249-5860
- first_name: Georg M
full_name: Arnold, Georg M
id: 3770C838-F248-11E8-B48F-1D18A9856A87
last_name: Arnold
- first_name: Liu
full_name: Qiu, Liu
id: 45e99c0d-1eb1-11eb-9b96-ed8ab2983cac
last_name: Qiu
orcid: 0000-0003-4345-4267
- first_name: Johannes M
full_name: Fink, Johannes M
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
citation:
ama: 'Sahu R, Hease WJ, Rueda Sanchez AR, Arnold GM, Qiu L, Fink JM. Realizing a
quantum-enabled interconnect between microwave and telecom light. In: Conference
on Lasers and Electro-Optics. Optica Publishing Group; 2022. doi:10.1364/CLEO_QELS.2022.FW4D.4'
apa: 'Sahu, R., Hease, W. J., Rueda Sanchez, A. R., Arnold, G. M., Qiu, L., &
Fink, J. M. (2022). Realizing a quantum-enabled interconnect between microwave
and telecom light. In Conference on Lasers and Electro-Optics. San Jose,
CA, United States: Optica Publishing Group. https://doi.org/10.1364/CLEO_QELS.2022.FW4D.4'
chicago: Sahu, Rishabh, William J Hease, Alfredo R Rueda Sanchez, Georg M Arnold,
Liu Qiu, and Johannes M Fink. “Realizing a Quantum-Enabled Interconnect between
Microwave and Telecom Light.” In Conference on Lasers and Electro-Optics.
Optica Publishing Group, 2022. https://doi.org/10.1364/CLEO_QELS.2022.FW4D.4.
ieee: R. Sahu, W. J. Hease, A. R. Rueda Sanchez, G. M. Arnold, L. Qiu, and J. M.
Fink, “Realizing a quantum-enabled interconnect between microwave and telecom
light,” in Conference on Lasers and Electro-Optics, San Jose, CA, United
States, 2022.
ista: 'Sahu R, Hease WJ, Rueda Sanchez AR, Arnold GM, Qiu L, Fink JM. 2022. Realizing
a quantum-enabled interconnect between microwave and telecom light. Conference
on Lasers and Electro-Optics. CLEO: QELS Fundamental Science, FW4D.4.'
mla: Sahu, Rishabh, et al. “Realizing a Quantum-Enabled Interconnect between Microwave
and Telecom Light.” Conference on Lasers and Electro-Optics, FW4D.4, Optica
Publishing Group, 2022, doi:10.1364/CLEO_QELS.2022.FW4D.4.
short: R. Sahu, W.J. Hease, A.R. Rueda Sanchez, G.M. Arnold, L. Qiu, J.M. Fink,
in:, Conference on Lasers and Electro-Optics, Optica Publishing Group, 2022.
conference:
end_date: 2022-05-20
location: San Jose, CA, United States
name: 'CLEO: QELS Fundamental Science'
start_date: 2022-05-15
date_created: 2022-09-11T22:01:58Z
date_published: 2022-05-01T00:00:00Z
date_updated: 2023-02-13T09:06:10Z
day: '01'
department:
- _id: JoFi
doi: 10.1364/CLEO_QELS.2022.FW4D.4
language:
- iso: eng
month: '05'
oa_version: None
publication: Conference on Lasers and Electro-Optics
publication_identifier:
isbn:
- '9781557528209'
publication_status: published
publisher: Optica Publishing Group
quality_controlled: '1'
scopus_import: '1'
status: public
title: Realizing a quantum-enabled interconnect between microwave and telecom light
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2022'
...
---
_id: '12101'
abstract:
- lang: eng
text: 'Spatial games form a widely-studied class of games from biology and physics
modeling the evolution of social behavior. Formally, such a game is defined by
a square (d by d) payoff matrix M and an undirected graph G. Each vertex of G
represents an individual, that initially follows some strategy i ∈ {1,2,…,d}.
In each round of the game, every individual plays the matrix game with each of
its neighbors: An individual following strategy i meeting a neighbor following
strategy j receives a payoff equal to the entry (i,j) of M. Then, each individual
updates its strategy to its neighbors'' strategy with the highest sum of payoffs,
and the next round starts. The basic computational problems consist of reachability
between configurations and the average frequency of a strategy. For general spatial
games and graphs, these problems are in PSPACE. In this paper, we examine restricted
setting: the game is a prisoner’s dilemma; and G is a subgraph of grid. We prove
that basic computational problems for spatial games with prisoner’s dilemma on
a subgraph of a grid are PSPACE-hard.'
acknowledgement: "Krishnendu Chatterjee: The research was partially supported by the
ERC CoG 863818\r\n(ForM-SMArt).\r\nIsmaël Jecker: The research was partially supported
by the ERC grant 950398 (INFSYS).\r\nJakub Svoboda: The research was partially supported
by the ERC CoG 863818 (ForM-SMArt)"
article_number: 11:1-11:14
article_processing_charge: No
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Rasmus
full_name: Ibsen-Jensen, Rasmus
id: 3B699956-F248-11E8-B48F-1D18A9856A87
last_name: Ibsen-Jensen
orcid: 0000-0003-4783-0389
- first_name: Ismael R
full_name: Jecker, Ismael R
id: 85D7C63E-7D5D-11E9-9C0F-98C4E5697425
last_name: Jecker
- first_name: Jakub
full_name: Svoboda, Jakub
id: 130759D2-D7DD-11E9-87D2-DE0DE6697425
last_name: Svoboda
orcid: 0000-0002-1419-3267
citation:
ama: 'Chatterjee K, Ibsen-Jensen R, Jecker IR, Svoboda J. Complexity of spatial
games. In: 42nd IARCS Annual Conference on Foundations of Software Technology
and Theoretical Computer Science. Vol 250. Schloss Dagstuhl - Leibniz-Zentrum
für Informatik; 2022. doi:10.4230/LIPIcs.FSTTCS.2022.11'
apa: 'Chatterjee, K., Ibsen-Jensen, R., Jecker, I. R., & Svoboda, J. (2022).
Complexity of spatial games. In 42nd IARCS Annual Conference on Foundations
of Software Technology and Theoretical Computer Science (Vol. 250). Madras,
India: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. https://doi.org/10.4230/LIPIcs.FSTTCS.2022.11'
chicago: Chatterjee, Krishnendu, Rasmus Ibsen-Jensen, Ismael R Jecker, and Jakub
Svoboda. “Complexity of Spatial Games.” In 42nd IARCS Annual Conference on
Foundations of Software Technology and Theoretical Computer Science, Vol.
250. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2022. https://doi.org/10.4230/LIPIcs.FSTTCS.2022.11.
ieee: K. Chatterjee, R. Ibsen-Jensen, I. R. Jecker, and J. Svoboda, “Complexity
of spatial games,” in 42nd IARCS Annual Conference on Foundations of Software
Technology and Theoretical Computer Science, Madras, India, 2022, vol. 250.
ista: 'Chatterjee K, Ibsen-Jensen R, Jecker IR, Svoboda J. 2022. Complexity of spatial
games. 42nd IARCS Annual Conference on Foundations of Software Technology and
Theoretical Computer Science. FSTTC: Foundations of Software Technology and Theoretical
Computer Science vol. 250, 11:1-11:14.'
mla: Chatterjee, Krishnendu, et al. “Complexity of Spatial Games.” 42nd IARCS
Annual Conference on Foundations of Software Technology and Theoretical Computer
Science, vol. 250, 11:1-11:14, Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
2022, doi:10.4230/LIPIcs.FSTTCS.2022.11.
short: K. Chatterjee, R. Ibsen-Jensen, I.R. Jecker, J. Svoboda, in:, 42nd IARCS
Annual Conference on Foundations of Software Technology and Theoretical Computer
Science, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2022.
conference:
end_date: 2022-12-20
location: Madras, India
name: 'FSTTC: Foundations of Software Technology and Theoretical Computer Science'
start_date: 2022-12-18
date_created: 2023-01-01T23:00:50Z
date_published: 2022-12-14T00:00:00Z
date_updated: 2025-07-14T09:09:55Z
day: '14'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.4230/LIPIcs.FSTTCS.2022.11
ec_funded: 1
file:
- access_level: open_access
checksum: a21e3ba2421e2c4a06aa2cb6d530ede1
content_type: application/pdf
creator: dernst
date_created: 2023-01-20T10:19:19Z
date_updated: 2023-01-20T10:19:19Z
file_id: '12323'
file_name: 2022_LIPICs_Chatterjee.pdf
file_size: 657396
relation: main_file
success: 1
file_date_updated: 2023-01-20T10:19:19Z
has_accepted_license: '1'
intvolume: ' 250'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
project:
- _id: 0599E47C-7A3F-11EA-A408-12923DDC885E
call_identifier: H2020
grant_number: '863818'
name: 'Formal Methods for Stochastic Models: Algorithms and Applications'
publication: 42nd IARCS Annual Conference on Foundations of Software Technology and
Theoretical Computer Science
publication_identifier:
isbn:
- '9783959772617'
issn:
- 1868-8969
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
quality_controlled: '1'
scopus_import: '1'
status: public
title: Complexity of spatial games
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 250
year: '2022'
...