[{"publisher":"Springer","article_type":"original","volume":225,"issue":"2","status":"public","month":"02","date_created":"2018-12-11T11:59:21Z","publist_id":"4153","intvolume":"       225","year":"2002","extern":"1","quality_controlled":"1","author":[{"id":"4DBD5372-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5366-9603","full_name":"Erdös, László","last_name":"Erdös","first_name":"László"},{"full_name":"Vougalter, Vitali","last_name":"Vougalter","first_name":"Vitali"}],"citation":{"mla":"Erdös, László, and Vitali Vougalter. “Pauli Operator and Aharonov–Casher Theorem¶ for Measure Valued Magnetic Fields.” <i>Communications in Mathematical Physics</i>, vol. 225, no. 2, Springer, 2002, pp. 399–421, doi:<a href=\"https://doi.org/10.1007/s002200100585\">10.1007/s002200100585</a>.","apa":"Erdös, L., &#38; Vougalter, V. (2002). Pauli operator and Aharonov–Casher theorem¶ for measure valued magnetic fields. <i>Communications in Mathematical Physics</i>. Springer. <a href=\"https://doi.org/10.1007/s002200100585\">https://doi.org/10.1007/s002200100585</a>","ama":"Erdös L, Vougalter V. Pauli operator and Aharonov–Casher theorem¶ for measure valued magnetic fields. <i>Communications in Mathematical Physics</i>. 2002;225(2):399-421. doi:<a href=\"https://doi.org/10.1007/s002200100585\">10.1007/s002200100585</a>","ieee":"L. Erdös and V. Vougalter, “Pauli operator and Aharonov–Casher theorem¶ for measure valued magnetic fields,” <i>Communications in Mathematical Physics</i>, vol. 225, no. 2. Springer, pp. 399–421, 2002.","chicago":"Erdös, László, and Vitali Vougalter. “Pauli Operator and Aharonov–Casher Theorem¶ for Measure Valued Magnetic Fields.” <i>Communications in Mathematical Physics</i>. Springer, 2002. <a href=\"https://doi.org/10.1007/s002200100585\">https://doi.org/10.1007/s002200100585</a>.","short":"L. Erdös, V. Vougalter, Communications in Mathematical Physics 225 (2002) 399–421.","ista":"Erdös L, Vougalter V. 2002. Pauli operator and Aharonov–Casher theorem¶ for measure valued magnetic fields. Communications in Mathematical Physics. 225(2), 399–421."},"abstract":[{"lang":"eng","text":"We define the two dimensional Pauli operator and identify its core for magnetic fields that are regular Borel measures. The magnetic field is generated by a scalar potential hence we bypass the usual A L 2loc condition on the vector potential, which does not allow to consider such singular fields. We extend the Aharonov-Casher theorem for magnetic fields that are measures with finite total variation and we present a counterexample in case of infinite total variation. One of the key technical tools is a weighted L 2 estimate on a singular integral operator."}],"publication_status":"published","_id":"2739","publication":"Communications in Mathematical Physics","title":"Pauli operator and Aharonov–Casher theorem¶ for measure valued magnetic fields","page":"399 - 421","external_id":{"arxiv":["math-ph/0109015v1"]},"date_published":"2002-02-01T00:00:00Z","arxiv":1,"scopus_import":"1","publication_identifier":{"issn":["0010-3616"]},"day":"01","oa_version":"None","date_updated":"2023-07-18T08:57:54Z","type":"journal_article","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","article_processing_charge":"No","acknowledgement":"This work started during the first author’s visit at the Erwin Schrödinger Institute, Vienna.\r\nValuable discussions with T. Hoffmann-Ostenhof and M. Loss are gratefully acknowledged. The authors thank\r\nthe referee for careful reading and comments","doi":"10.1007/s002200100585","language":[{"iso":"eng"}]},{"publication_identifier":{"issn":["0373-0956"]},"scopus_import":"1","page":"1833-1874","date_published":"2002-01-01T00:00:00Z","doi":"10.5802/aif.1936","language":[{"iso":"eng"}],"day":"01","type":"journal_article","date_updated":"2023-07-18T08:38:34Z","oa_version":"None","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","article_processing_charge":"No","status":"public","date_created":"2018-12-11T11:59:21Z","month":"01","publist_id":"4152","intvolume":"        52","article_type":"original","publisher":"Association des Annales de l'Institut Fourier","volume":52,"issue":"6","publication_status":"published","abstract":[{"lang":"eng","text":"We show that the lowest eigenvalue of the magnetic Schrödinger operator on a line bundle over a compact Riemann surface M is bounded by the L1-norm of the magnetic field B. This implies a similar bound on the multiplicity of the ground state. An example shows that this degeneracy can indeed be comparable with ∫M |B| even in case of the trivial bundle."}],"_id":"2740","publication":"Annales de l'Institut Fourier","title":"Spectral shift and multiplicity of the first eigenvalue of the magnetic Schrödinger operator in two dimensions","year":"2002","quality_controlled":"1","extern":"1","author":[{"last_name":"Erdös","first_name":"László","full_name":"Erdös, László","orcid":"0000-0001-5366-9603","id":"4DBD5372-F248-11E8-B48F-1D18A9856A87"}],"citation":{"apa":"Erdös, L. (2002). Spectral shift and multiplicity of the first eigenvalue of the magnetic Schrödinger operator in two dimensions. <i>Annales de l’Institut Fourier</i>. Association des Annales de l’Institut Fourier. <a href=\"https://doi.org/10.5802/aif.1936\">https://doi.org/10.5802/aif.1936</a>","mla":"Erdös, László. “Spectral Shift and Multiplicity of the First Eigenvalue of the Magnetic Schrödinger Operator in Two Dimensions.” <i>Annales de l’Institut Fourier</i>, vol. 52, no. 6, Association des Annales de l’Institut Fourier, 2002, pp. 1833–74, doi:<a href=\"https://doi.org/10.5802/aif.1936\">10.5802/aif.1936</a>.","chicago":"Erdös, László. “Spectral Shift and Multiplicity of the First Eigenvalue of the Magnetic Schrödinger Operator in Two Dimensions.” <i>Annales de l’Institut Fourier</i>. Association des Annales de l’Institut Fourier, 2002. <a href=\"https://doi.org/10.5802/aif.1936\">https://doi.org/10.5802/aif.1936</a>.","short":"L. Erdös, Annales de l’Institut Fourier 52 (2002) 1833–1874.","ista":"Erdös L. 2002. Spectral shift and multiplicity of the first eigenvalue of the magnetic Schrödinger operator in two dimensions. Annales de l’Institut Fourier. 52(6), 1833–1874.","ama":"Erdös L. Spectral shift and multiplicity of the first eigenvalue of the magnetic Schrödinger operator in two dimensions. <i>Annales de l’Institut Fourier</i>. 2002;52(6):1833-1874. doi:<a href=\"https://doi.org/10.5802/aif.1936\">10.5802/aif.1936</a>","ieee":"L. Erdös, “Spectral shift and multiplicity of the first eigenvalue of the magnetic Schrödinger operator in two dimensions,” <i>Annales de l’Institut Fourier</i>, vol. 52, no. 6. Association des Annales de l’Institut Fourier, pp. 1833–1874, 2002."}},{"scopus_import":"1","publication_identifier":{"issn":["0890-9369"]},"page":"1610 - 1615","external_id":{"pmid":["12101120"]},"date_published":"2002-07-01T00:00:00Z","acknowledgement":"We thank C. Maulbetsch for isolating BDL cDNA clones; T. Berleth and J. Friml for providing clones for in situ probes; K. Harter for making available the parsley protoplast system; and J. Friml, N. Geldner, M. Griffith, C. Schwechheimer, D. Weigel, and D. Weijers for helpful comments and critical reading of the manuscript. This work was supported by Sonderforschungsbereich 446 “Mechanismen des Zellverhaltens bei Eukaryoten.”\r\n\r\nThe publication costs of this article were defrayed in part by payment of page charges. This article must therefore be hereby marked “advertisement” in accordance with 18 USC section 1734 solely to indicate this fact.","doi":"10.1101/gad.229402","language":[{"iso":"eng"}],"day":"01","oa_version":"Published Version","date_updated":"2023-07-18T08:26:58Z","type":"journal_article","article_processing_charge":"No","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","status":"public","month":"07","date_created":"2018-12-11T12:00:01Z","publist_id":"3921","intvolume":"        16","article_type":"original","publisher":"Cold Spring Harbor Laboratory Press","issue":"13","volume":16,"abstract":[{"text":"Developmental responses to the plant hormone auxin are thought to be mediated by interacting pairs from two protein families: short-lived inhibitory IAA proteins and ARF transcription factors binding to auxin-response elements. Monopteros mutants lacking activating ARF5 and the auxin-insensitive mutant bodenlos fail to initiate the root meristem during early embryogenesis. Here we show that the bodenlos phenotype results from an amino-acid exchange in the conserved degradation domain of IAA12. BODENLOS and MONOPTEROS interact in the yeast two-hybrid assay and the two genes are coexpressed in early embryogenesis, suggesting that BODENLOS inhibits MONOPTEROS action in root meristem initiation.","lang":"eng"}],"publication_status":"published","_id":"2866","oa":1,"pmid":1,"title":"The Arabidopsis BODENLOS gene encodes an auxin response protein inhibiting MONOPTEROS-mediated embryo patterning","publication":"Genes and Development","year":"2002","author":[{"full_name":"Hamann, Thorsten","last_name":"Hamann","first_name":"Thorsten"},{"id":"38F4F166-F248-11E8-B48F-1D18A9856A87","full_name":"Benková, Eva","orcid":"0000-0002-8510-9739","last_name":"Benková","first_name":"Eva"},{"full_name":"Bäurle, Isabel","first_name":"Isabel","last_name":"Bäurle"},{"first_name":"Marika","last_name":"Kientz","full_name":"Kientz, Marika"},{"first_name":"Gerd","last_name":"Jürgens","full_name":"Jürgens, Gerd"}],"extern":"1","quality_controlled":"1","citation":{"apa":"Hamann, T., Benková, E., Bäurle, I., Kientz, M., &#38; Jürgens, G. (2002). The Arabidopsis BODENLOS gene encodes an auxin response protein inhibiting MONOPTEROS-mediated embryo patterning. <i>Genes and Development</i>. Cold Spring Harbor Laboratory Press. <a href=\"https://doi.org/10.1101/gad.229402\">https://doi.org/10.1101/gad.229402</a>","mla":"Hamann, Thorsten, et al. “The Arabidopsis BODENLOS Gene Encodes an Auxin Response Protein Inhibiting MONOPTEROS-Mediated Embryo Patterning.” <i>Genes and Development</i>, vol. 16, no. 13, Cold Spring Harbor Laboratory Press, 2002, pp. 1610–15, doi:<a href=\"https://doi.org/10.1101/gad.229402\">10.1101/gad.229402</a>.","ista":"Hamann T, Benková E, Bäurle I, Kientz M, Jürgens G. 2002. The Arabidopsis BODENLOS gene encodes an auxin response protein inhibiting MONOPTEROS-mediated embryo patterning. Genes and Development. 16(13), 1610–1615.","chicago":"Hamann, Thorsten, Eva Benková, Isabel Bäurle, Marika Kientz, and Gerd Jürgens. “The Arabidopsis BODENLOS Gene Encodes an Auxin Response Protein Inhibiting MONOPTEROS-Mediated Embryo Patterning.” <i>Genes and Development</i>. Cold Spring Harbor Laboratory Press, 2002. <a href=\"https://doi.org/10.1101/gad.229402\">https://doi.org/10.1101/gad.229402</a>.","short":"T. Hamann, E. Benková, I. Bäurle, M. Kientz, G. Jürgens, Genes and Development 16 (2002) 1610–1615.","ama":"Hamann T, Benková E, Bäurle I, Kientz M, Jürgens G. The Arabidopsis BODENLOS gene encodes an auxin response protein inhibiting MONOPTEROS-mediated embryo patterning. <i>Genes and Development</i>. 2002;16(13):1610-1615. doi:<a href=\"https://doi.org/10.1101/gad.229402\">10.1101/gad.229402</a>","ieee":"T. Hamann, E. Benková, I. Bäurle, M. Kientz, and G. Jürgens, “The Arabidopsis BODENLOS gene encodes an auxin response protein inhibiting MONOPTEROS-mediated embryo patterning,” <i>Genes and Development</i>, vol. 16, no. 13. Cold Spring Harbor Laboratory Press, pp. 1610–1615, 2002."},"main_file_link":[{"open_access":"1","url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC186366/"}]},{"citation":{"ama":"Kolmogorov V, Zabih R. Multi-camera scene reconstruction via graph cuts. In: <i>Proceedings of the 7th European Conference on Computer Vision</i>. Springer; 2002:65-81. doi:<a href=\"https://doi.org/10.1007/3-540-47977-5_5\">10.1007/3-540-47977-5_5</a>","ieee":"V. Kolmogorov and R. Zabih, “Multi-camera scene reconstruction via graph cuts,” in <i>Proceedings of the 7th European Conference on Computer Vision</i>, Copenhagen, Denmark, 2002, pp. 65–81.","short":"V. Kolmogorov, R. Zabih, in:, Proceedings of the 7th European Conference on Computer Vision, Springer, 2002, pp. 65–81.","chicago":"Kolmogorov, Vladimir, and Ramin Zabih. “Multi-Camera Scene Reconstruction via Graph Cuts.” In <i>Proceedings of the 7th European Conference on Computer Vision</i>, 65–81. Springer, 2002. <a href=\"https://doi.org/10.1007/3-540-47977-5_5\">https://doi.org/10.1007/3-540-47977-5_5</a>.","ista":"Kolmogorov V, Zabih R. 2002. Multi-camera scene reconstruction via graph cuts. Proceedings of the 7th European Conference on Computer Vision. ECCV: European Conference on Computer Vision, 65–81.","apa":"Kolmogorov, V., &#38; Zabih, R. (2002). Multi-camera scene reconstruction via graph cuts. In <i>Proceedings of the 7th European Conference on Computer Vision</i> (pp. 65–81). Copenhagen, Denmark: Springer. <a href=\"https://doi.org/10.1007/3-540-47977-5_5\">https://doi.org/10.1007/3-540-47977-5_5</a>","mla":"Kolmogorov, Vladimir, and Ramin Zabih. “Multi-Camera Scene Reconstruction via Graph Cuts.” <i>Proceedings of the 7th European Conference on Computer Vision</i>, Springer, 2002, pp. 65–81, doi:<a href=\"https://doi.org/10.1007/3-540-47977-5_5\">10.1007/3-540-47977-5_5</a>."},"article_processing_charge":"No","extern":"1","author":[{"full_name":"Kolmogorov, Vladimir","id":"3D50B0BA-F248-11E8-B48F-1D18A9856A87","first_name":"Vladimir","last_name":"Kolmogorov"},{"last_name":"Zabih","first_name":"Ramin","full_name":"Zabih, Ramin"}],"quality_controlled":"1","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","date_updated":"2023-07-18T08:20:02Z","type":"conference","oa_version":"None","day":"01","year":"2002","title":"Multi-camera scene reconstruction via graph cuts","publication":"Proceedings of the 7th European Conference on Computer Vision","doi":"10.1007/3-540-47977-5_5","language":[{"iso":"eng"}],"_id":"2927","acknowledgement":"We thank Olga Veksler and Yuri Boykov for their careful reading of this paper, and for valuable comments which greatly improved itsreadibility. We also thank Ian Jermyn for helping us clarify the paper’s motivation. This research was supported by NSF grants IIS-9900115 and CCR-0113371, and by a grant from Microsoft Research.","publication_status":"published","abstract":[{"text":"In the last few years, several new algorithms based on graph cuts have been developed to solve energy minimization problems in computer vision. Each of these techniques constructs a graph such that the minimum cut on the graph also minimizes the energy. Yet because these graph constructions are complex and highly specific to a particular energy function, graph cuts have seen limited application to date. In this paper we characterize the energy functions that can be minimized by graph cuts. Our results are restricted to energy functions with binary variables. However, our work generalizes many previous constructions, and is easily applicable to vision problems that involve large numbers of labels, such as stereo, motion, image restoration and scene reconstruction. We present three main results: a necessary condition for any energy function that can be minimized by graph cuts; a sufficient condition for energy functions that can be written as a sum of functions of up to three variables at a time; and a general-purpose construction to minimize such an energy function. Researchers who are considering the use of graph cuts to optimize a particular energy function can use our results to determine if this is possible, and then follow our construction to create the appropriate graph.","lang":"eng"}],"date_published":"2002-01-01T00:00:00Z","page":"65 - 81","publisher":"Springer","publist_id":"3810","publication_identifier":{"isbn":["9783540437468"]},"scopus_import":"1","date_created":"2018-12-11T12:00:23Z","month":"01","conference":{"start_date":"2002-05-28","location":"Copenhagen, Denmark","end_date":"2002-05-31","name":"ECCV: European Conference on Computer Vision"},"status":"public"},{"extern":"1","author":[{"first_name":"Jirí","last_name":"Friml","orcid":"0000-0002-8302-7596","full_name":"Friml, Jirí","id":"4159519E-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Wiśniewska, Justyna","first_name":"Justyna","last_name":"Wiśniewska"},{"id":"38F4F166-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8510-9739","full_name":"Benková, Eva","last_name":"Benková","first_name":"Eva"},{"first_name":"Kurt","last_name":"Mendgen","full_name":"Mendgen, Kurt"},{"full_name":"Palme, Klaus","last_name":"Palme","first_name":"Klaus"}],"quality_controlled":"1","citation":{"mla":"Friml, Jiří, et al. “Lateral Relocation of Auxin Efflux Regulator PIN3 Mediates Tropism in Arabidopsis.” <i>Nature</i>, vol. 415, no. 6873, Nature Publishing Group, 2002, pp. 806–09, doi:<a href=\"https://doi.org/10.1038/415806a\">10.1038/415806a</a>.","apa":"Friml, J., Wiśniewska, J., Benková, E., Mendgen, K., &#38; Palme, K. (2002). Lateral relocation of auxin efflux regulator PIN3 mediates tropism in Arabidopsis. <i>Nature</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/415806a\">https://doi.org/10.1038/415806a</a>","ista":"Friml J, Wiśniewska J, Benková E, Mendgen K, Palme K. 2002. Lateral relocation of auxin efflux regulator PIN3 mediates tropism in Arabidopsis. Nature. 415(6873), 806–809.","chicago":"Friml, Jiří, Justyna Wiśniewska, Eva Benková, Kurt Mendgen, and Klaus Palme. “Lateral Relocation of Auxin Efflux Regulator PIN3 Mediates Tropism in Arabidopsis.” <i>Nature</i>. Nature Publishing Group, 2002. <a href=\"https://doi.org/10.1038/415806a\">https://doi.org/10.1038/415806a</a>.","short":"J. Friml, J. Wiśniewska, E. Benková, K. Mendgen, K. Palme, Nature 415 (2002) 806–809.","ama":"Friml J, Wiśniewska J, Benková E, Mendgen K, Palme K. Lateral relocation of auxin efflux regulator PIN3 mediates tropism in Arabidopsis. <i>Nature</i>. 2002;415(6873):806-809. doi:<a href=\"https://doi.org/10.1038/415806a\">10.1038/415806a</a>","ieee":"J. Friml, J. Wiśniewska, E. Benková, K. Mendgen, and K. Palme, “Lateral relocation of auxin efflux regulator PIN3 mediates tropism in Arabidopsis,” <i>Nature</i>, vol. 415, no. 6873. Nature Publishing Group, pp. 806–809, 2002."},"year":"2002","_id":"2986","pmid":1,"publication":"Nature","title":"Lateral relocation of auxin efflux regulator PIN3 mediates tropism in Arabidopsis","abstract":[{"text":"Long-standing models propose that plant growth responses to light or gravity are mediated by asymmetric distribution of the phytohormone auxin. Physiological studies implicated a specific transport system that relocates auxin laterally, thereby effecting differential growth; however, neither the molecular components of this system nor the cellular mechanism of auxin redistribution on light or gravity perception have been identified. Here, we show that auxin accumulates asymmetrically during differential growth in an efflux-dependent manner. Mutations in the Arabidopsis gene PIN3, a regulator of auxin efflux, alter differential growth. PIN3 is expressed in gravity-sensing tissues, with PIN3 protein accumulating predominantly at the lateral cell surface. PIN3 localizes to the plasma membrane and to vesicles that cycle in an actin-dependent manner. In the root columella, PIN3 is positioned symmetrically at the plasma membrane but rapidly relocalizes laterally on gravity stimulation. Our data indicate that PIN3 is a component of the lateral auxin transport system regulating tropic growth. In addition, actin-dependent relocalization of PIN3 in response to gravity provides a mechanism for redirecting auxin flux to trigger asymmetric growth.","lang":"eng"}],"publication_status":"published","issue":"6873","volume":415,"publisher":"Nature Publishing Group","article_type":"original","publist_id":"3715","intvolume":"       415","status":"public","month":"02","date_created":"2018-12-11T12:00:42Z","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","article_processing_charge":"No","day":"14","oa_version":"None","date_updated":"2023-07-18T07:30:27Z","type":"journal_article","language":[{"iso":"eng"}],"doi":"10.1038/415806a","acknowledgement":"We thank G. Jürgens for enabling J.F. to accomplish part of this work in his laboratory; P. Tänzler and M. Sauer for technical assistance; H. Vahlenkamp for technical assistance in immunocytochemistry; M. Estelle for providing material and suggestions; T. Altman for BAC filter sets; the ADIS (Automated DNA Isolation and Sequencing) service group for DNA sequencing; ZIGIA (Center for Functional Genomics in Arabidopsis) for the En lines; and N. Geldner, T. Hamann, G. Jürgens, K. Schrick and C. Schwechheimer for comments and critical reading of the manuscript. This work was supported by a fellowship of the DAAD (J.F.), the DFG (Schwerpunktprogramm Phytohormone), the Fonds der chemischen Industrie, the European Communities Biotechnology Programs, the INCO-Copernicus Program and the European Space Agency MAP-Biotechnology Programme","page":"806 - 809","external_id":{"pmid":["11845211 "]},"date_published":"2002-02-14T00:00:00Z","scopus_import":"1","publication_identifier":{"issn":["0028-0836"]}},{"issue":"5","volume":14,"article_type":"original","publisher":"American Society of Plant Biologists","publist_id":"3716","intvolume":"        14","status":"public","month":"05","date_created":"2018-12-11T12:00:42Z","quality_controlled":"1","author":[{"full_name":"Souter, Martin","first_name":"Martin","last_name":"Souter"},{"full_name":"Topping, Jennifer","last_name":"Topping","first_name":"Jennifer"},{"last_name":"Pullen","first_name":"Margaret","full_name":"Pullen, Margaret"},{"last_name":"Friml","first_name":"Jirí","id":"4159519E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8302-7596","full_name":"Friml, Jirí"},{"first_name":"Klaus","last_name":"Palme","full_name":"Palme, Klaus"},{"full_name":"Hackett, Rachel","first_name":"Rachel","last_name":"Hackett"},{"full_name":"Grierson, Don","last_name":"Grierson","first_name":"Don"},{"last_name":"Lindsey","first_name":"Keith","full_name":"Lindsey, Keith"}],"extern":"1","citation":{"mla":"Souter, Martin, et al. “Hydra Mutants of Arabidopsis Are Defective in Sterol Profiles and Auxin and Ethylene Signaling.” <i>Plant Cell</i>, vol. 14, no. 5, American Society of Plant Biologists, 2002, pp. 1017–31, doi:<a href=\"https://doi.org/10.1105/tpc.001248\">10.1105/tpc.001248</a>.","apa":"Souter, M., Topping, J., Pullen, M., Friml, J., Palme, K., Hackett, R., … Lindsey, K. (2002). Hydra mutants of Arabidopsis are defective in sterol profiles and auxin and ethylene signaling. <i>Plant Cell</i>. American Society of Plant Biologists. <a href=\"https://doi.org/10.1105/tpc.001248\">https://doi.org/10.1105/tpc.001248</a>","ama":"Souter M, Topping J, Pullen M, et al. Hydra mutants of Arabidopsis are defective in sterol profiles and auxin and ethylene signaling. <i>Plant Cell</i>. 2002;14(5):1017-1031. doi:<a href=\"https://doi.org/10.1105/tpc.001248\">10.1105/tpc.001248</a>","ieee":"M. Souter <i>et al.</i>, “Hydra mutants of Arabidopsis are defective in sterol profiles and auxin and ethylene signaling,” <i>Plant Cell</i>, vol. 14, no. 5. American Society of Plant Biologists, pp. 1017–1031, 2002.","ista":"Souter M, Topping J, Pullen M, Friml J, Palme K, Hackett R, Grierson D, Lindsey K. 2002. Hydra mutants of Arabidopsis are defective in sterol profiles and auxin and ethylene signaling. Plant Cell. 14(5), 1017–1031.","chicago":"Souter, Martin, Jennifer Topping, Margaret Pullen, Jiří Friml, Klaus Palme, Rachel Hackett, Don Grierson, and Keith Lindsey. “Hydra Mutants of Arabidopsis Are Defective in Sterol Profiles and Auxin and Ethylene Signaling.” <i>Plant Cell</i>. American Society of Plant Biologists, 2002. <a href=\"https://doi.org/10.1105/tpc.001248\">https://doi.org/10.1105/tpc.001248</a>.","short":"M. Souter, J. Topping, M. Pullen, J. Friml, K. Palme, R. Hackett, D. Grierson, K. Lindsey, Plant Cell 14 (2002) 1017–1031."},"main_file_link":[{"open_access":"1","url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC150604/"}],"year":"2002","_id":"2987","oa":1,"pmid":1,"title":"Hydra mutants of Arabidopsis are defective in sterol profiles and auxin and ethylene signaling","publication":"Plant Cell","abstract":[{"text":"The hydra mutants of Arabidopsis are characterized by a pleiotropic phenotype that shows defective embryonic and seedling cell patterning, morphogenesis, and root growth. We demonstrate that the HYDRA1 gene encodes a Δ8-Δ7 sterol isomerase, whereas HYDRA2 encodes a sterol C14 reductase, previously identified as the FACKEL gene product. Seedlings mutant for each gene are similarly defective in the concentrations of the three major Arabidopsis sterols. Promoter::reporter gene analysis showed misexpression of the auxin-regulated DR5 and ACS1 promoters and of the epidermal cell file-specific GL2 promoter in the mutants. The mutants exhibit enhanced responses to auxin. The phenotypes can be rescued partially by inhibition of auxin and ethylene signaling but not by exogenous sterols or brassinosteroids. We propose a model in which correct sterol profiles are required for regulated auxin and ethylene signaling through effects on membrane function.","lang":"eng"}],"publication_status":"published","page":"1017 - 1031","external_id":{"pmid":["12034894"]},"date_published":"2002-05-01T00:00:00Z","scopus_import":"1","publication_identifier":{"issn":["1040-4651"]},"article_processing_charge":"No","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","day":"01","oa_version":"None","type":"journal_article","date_updated":"2023-07-18T07:34:32Z","language":[{"iso":"eng"}],"doi":"10.1105/tpc.001248","acknowledgement":"We thank Dr. Ken Feldmann for providing prospective hyd alleles, Dr. Jane Murfett for providing DR5::GUS seed, Dr. D. Van Der Straeten for providing ACS1::GUS seed, Dr. John Schiefelbein for providing GL2::GFP seed, and Dr. Ottoline Leyser for axr1-12 and axr3-1 seed. etr1 and fk seed was obtained from the Nottingham Arabidopsis Stock Centre. This work was supported by a Biotechnology and Biological Science Research Council research studentship to M.S., a Durham University studentship to M.P., and Biotechnology and Biological Science Research Council Grant 12/P02330 to J.T."},{"doi":"10.1016/S0960-9822(02)00654-1","language":[{"iso":"eng"}],"article_processing_charge":"No","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","day":"19","oa_version":"None","type":"journal_article","date_updated":"2023-07-17T12:15:28Z","scopus_import":"1","publication_identifier":{"issn":["0960-9822"]},"page":"329 - 334","external_id":{"pmid":["11864575"]},"date_published":"2002-02-19T00:00:00Z","_id":"2988","pmid":1,"title":"Cell polarity signaling in Arabidopsis involves a BFA sensitive auxin influx pathway","publication":"Current Biology","abstract":[{"text":"Coordination of cell and tissue polarity commonly involves directional signaling [1]. In the Arabidopsis root epidermis, cell polarity is revealed by basal, root tip-oriented, hair outgrowth from hair-forming cells (trichoblasts) [2]. The plant hormone auxin displays polar movements [1, 3] and accumulates at maximum concentration in the root tip [4, 5]. The application of polar auxin transport inhibitors [3] evokes changes in trichoblast polarity only at high concentrations and after long-term application [2, 4]. Thus, it remains open whether components of the auxin transport machinery mediate establishment of trichoblast polarity. Here we report that the presumptive auxin influx carrier AUX1 [6, 7] contributes to apical-basal hair cell polarity. AUX1 function is required for polarity changes induced by exogenous application of the auxin 2,4-D, a preferential influx carrier substrate. Similar to aux1 mutants, the vesicle trafficking inhibitor brefeldin A (BFA) interferes with polar hair initiation, and AUX1 function is required for BFA-mediated polarity changes. Consistently, BFA inhibits membrane trafficking of AUX1, trichoblast hyperpolarization induced by 2,4-D, and alters the distal auxin maximum. Our results identify AUX1 as one component of a novel BFA-sensitive auxin transport pathway polarizing cells toward a hormone maximum.","lang":"eng"}],"publication_status":"published","extern":"1","author":[{"first_name":"Markus","last_name":"Grebe","full_name":"Grebe, Markus"},{"orcid":"0000-0002-8302-7596","full_name":"Friml, Jirí","id":"4159519E-F248-11E8-B48F-1D18A9856A87","last_name":"Friml","first_name":"Jirí"},{"full_name":"Swarup, Ranjan","last_name":"Swarup","first_name":"Ranjan"},{"last_name":"Ljung","first_name":"Karin","full_name":"Ljung, Karin"},{"full_name":"Sandberg, Göran","first_name":"Göran","last_name":"Sandberg"},{"first_name":"Maarten","last_name":"Terlou","full_name":"Terlou, Maarten"},{"full_name":"Palme, Klaus","first_name":"Klaus","last_name":"Palme"},{"last_name":"Bennett","first_name":"Malcolm","full_name":"Bennett, Malcolm"},{"full_name":"Scheres, Ben","first_name":"Ben","last_name":"Scheres"}],"quality_controlled":"1","citation":{"ista":"Grebe M, Friml J, Swarup R, Ljung K, Sandberg G, Terlou M, Palme K, Bennett M, Scheres B. 2002. Cell polarity signaling in Arabidopsis involves a BFA sensitive auxin influx pathway. Current Biology. 12(4), 329–334.","short":"M. Grebe, J. Friml, R. Swarup, K. Ljung, G. Sandberg, M. Terlou, K. Palme, M. Bennett, B. Scheres, Current Biology 12 (2002) 329–334.","chicago":"Grebe, Markus, Jiří Friml, Ranjan Swarup, Karin Ljung, Göran Sandberg, Maarten Terlou, Klaus Palme, Malcolm Bennett, and Ben Scheres. “Cell Polarity Signaling in Arabidopsis Involves a BFA Sensitive Auxin Influx Pathway.” <i>Current Biology</i>. Cell Press, 2002. <a href=\"https://doi.org/10.1016/S0960-9822(02)00654-1\">https://doi.org/10.1016/S0960-9822(02)00654-1</a>.","ieee":"M. Grebe <i>et al.</i>, “Cell polarity signaling in Arabidopsis involves a BFA sensitive auxin influx pathway,” <i>Current Biology</i>, vol. 12, no. 4. Cell Press, pp. 329–334, 2002.","ama":"Grebe M, Friml J, Swarup R, et al. Cell polarity signaling in Arabidopsis involves a BFA sensitive auxin influx pathway. <i>Current Biology</i>. 2002;12(4):329-334. doi:<a href=\"https://doi.org/10.1016/S0960-9822(02)00654-1\">10.1016/S0960-9822(02)00654-1</a>","apa":"Grebe, M., Friml, J., Swarup, R., Ljung, K., Sandberg, G., Terlou, M., … Scheres, B. (2002). Cell polarity signaling in Arabidopsis involves a BFA sensitive auxin influx pathway. <i>Current Biology</i>. Cell Press. <a href=\"https://doi.org/10.1016/S0960-9822(02)00654-1\">https://doi.org/10.1016/S0960-9822(02)00654-1</a>","mla":"Grebe, Markus, et al. “Cell Polarity Signaling in Arabidopsis Involves a BFA Sensitive Auxin Influx Pathway.” <i>Current Biology</i>, vol. 12, no. 4, Cell Press, 2002, pp. 329–34, doi:<a href=\"https://doi.org/10.1016/S0960-9822(02)00654-1\">10.1016/S0960-9822(02)00654-1</a>."},"year":"2002","publist_id":"3714","intvolume":"        12","status":"public","month":"02","date_created":"2018-12-11T12:00:43Z","volume":12,"issue":"4","publisher":"Cell Press","article_type":"original"},{"volume":108,"issue":"5","article_type":"original","publisher":"Cell Press","intvolume":"       108","publist_id":"3713","date_created":"2018-12-11T12:00:43Z","month":"03","status":"public","citation":{"short":"J. Friml, E. Benková, I. Blilou, J. Wiśniewska, T. Hamann, K. Ljung, S. Woody, G. Sandberg, B. Scheres, G. Jürgens, K. Palme, Cell 108 (2002) 661–673.","chicago":"Friml, Jiří, Eva Benková, Ikram Blilou, Justyna Wiśniewska, Thorsten Hamann, Karin Ljung, Scott Woody, et al. “AtPIN4 Mediates Sink-Driven Auxin Gradients and Root Patterning in Arabidopsis.” <i>Cell</i>. Cell Press, 2002. <a href=\"https://doi.org/10.1016/S0092-8674(02)00656-6\">https://doi.org/10.1016/S0092-8674(02)00656-6</a>.","ista":"Friml J, Benková E, Blilou I, Wiśniewska J, Hamann T, Ljung K, Woody S, Sandberg G, Scheres B, Jürgens G, Palme K. 2002. AtPIN4 mediates sink-driven auxin gradients and root patterning in Arabidopsis. Cell. 108(5), 661–673.","ama":"Friml J, Benková E, Blilou I, et al. AtPIN4 mediates sink-driven auxin gradients and root patterning in Arabidopsis. <i>Cell</i>. 2002;108(5):661-673. doi:<a href=\"https://doi.org/10.1016/S0092-8674(02)00656-6\">10.1016/S0092-8674(02)00656-6</a>","ieee":"J. Friml <i>et al.</i>, “AtPIN4 mediates sink-driven auxin gradients and root patterning in Arabidopsis,” <i>Cell</i>, vol. 108, no. 5. Cell Press, pp. 661–673, 2002.","mla":"Friml, Jiří, et al. “AtPIN4 Mediates Sink-Driven Auxin Gradients and Root Patterning in Arabidopsis.” <i>Cell</i>, vol. 108, no. 5, Cell Press, 2002, pp. 661–73, doi:<a href=\"https://doi.org/10.1016/S0092-8674(02)00656-6\">10.1016/S0092-8674(02)00656-6</a>.","apa":"Friml, J., Benková, E., Blilou, I., Wiśniewska, J., Hamann, T., Ljung, K., … Palme, K. (2002). AtPIN4 mediates sink-driven auxin gradients and root patterning in Arabidopsis. <i>Cell</i>. Cell Press. <a href=\"https://doi.org/10.1016/S0092-8674(02)00656-6\">https://doi.org/10.1016/S0092-8674(02)00656-6</a>"},"extern":"1","quality_controlled":"1","author":[{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8302-7596","full_name":"Friml, Jirí","last_name":"Friml","first_name":"Jirí"},{"orcid":"0000-0002-8510-9739","full_name":"Benková, Eva","id":"38F4F166-F248-11E8-B48F-1D18A9856A87","first_name":"Eva","last_name":"Benková"},{"first_name":"Ikram","last_name":"Blilou","full_name":"Blilou, Ikram"},{"first_name":"Justyna","last_name":"Wiśniewska","full_name":"Wiśniewska, Justyna"},{"full_name":"Hamann, Thorsten","first_name":"Thorsten","last_name":"Hamann"},{"full_name":"Ljung, Karin","first_name":"Karin","last_name":"Ljung"},{"first_name":"Scott","last_name":"Woody","full_name":"Woody, Scott"},{"first_name":"Göran","last_name":"Sandberg","full_name":"Sandberg, Göran"},{"first_name":"Ben","last_name":"Scheres","full_name":"Scheres, Ben"},{"first_name":"Gerd","last_name":"Jürgens","full_name":"Jürgens, Gerd"},{"full_name":"Palme, Klaus","last_name":"Palme","first_name":"Klaus"}],"year":"2002","publication":"Cell","title":"AtPIN4 mediates sink-driven auxin gradients and root patterning in Arabidopsis","pmid":1,"_id":"2989","publication_status":"published","abstract":[{"lang":"eng","text":"In contrast to animals, little is known about pattern formation in plants. Physiological and genetic data suggest the involvement of the phytohormone auxin in this process. Here, we characterize a novel member of the PIN family of putative auxin efflux carriers, Arabidopsis PIN4, that is localized in developing and mature root meristems. Atpin4 mutants are defective in establishment and maintenance of endogenous auxin gradients, fail to canalize externally applied auxin, and display various patterning defects in both embryonic and seedling roots. We propose a role for AtPIN4 in generating a sink for auxin below the quiescent center of the root meristem that is essential for auxin distribution and patterning."}],"date_published":"2002-03-08T00:00:00Z","external_id":{"pmid":["11893337"]},"page":"661 - 673","publication_identifier":{"issn":["0092-8674"]},"scopus_import":"1","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","article_processing_charge":"No","type":"journal_article","date_updated":"2023-07-17T11:57:40Z","oa_version":"None","day":"08","doi":"10.1016/S0092-8674(02)00656-6","language":[{"iso":"eng"}],"acknowledgement":"We thank Petra Tänzler, Michaela Lehnen, and Thomas Steinmann for technical help. We acknowledge the Arabidopsis Biological Resource Center (Columbus, OH) and Thomas Altman for providing material. We also gratefully acknowledge the ADIS service group for DNA sequencing and ZIGIA (Center for Functional Genomics in Arabidopsis) for the En lines. We are grateful to our colleagues, particularly Leo Gälweiler, Niko Geldner, Matthias Godde, and Kathrin Schrick for critical reading of the manuscript. This work was supported by a fellowship of the Deutscher Akademischer Austauschdienset (J.F.), the Deutsche Forschungsgemeinschaft (Schwerpunktprogramm Phytohormone), the European Communities Biotechnology Programs, the Fonds der Chemischen Industrie, and the INCO-Copernicus Program."},{"quality_controlled":"1","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","extern":"1","author":[{"first_name":"Jirí","last_name":"Friml","orcid":"0000-0002-8302-7596","full_name":"Friml, Jirí","id":"4159519E-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Palme","first_name":"Klaus","full_name":"Palme, Klaus"}],"citation":{"apa":"Friml, J., &#38; Palme, K. (2002). Polar auxin transport - Old questions and new concepts? <i>Plant Molecular Biology</i>. Springer. <a href=\"https://doi.org/10.1023/A:1015248926412\">https://doi.org/10.1023/A:1015248926412</a>","mla":"Friml, Jiří, and Klaus Palme. “Polar Auxin Transport - Old Questions and New Concepts?” <i>Plant Molecular Biology</i>, vol. 49, no. 3–4, Springer, 2002, pp. 273–84, doi:<a href=\"https://doi.org/10.1023/A:1015248926412\">10.1023/A:1015248926412</a>.","ista":"Friml J, Palme K. 2002. Polar auxin transport - Old questions and new concepts? Plant Molecular Biology. 49(3–4), 273–284.","short":"J. Friml, K. Palme, Plant Molecular Biology 49 (2002) 273–284.","chicago":"Friml, Jiří, and Klaus Palme. “Polar Auxin Transport - Old Questions and New Concepts?” <i>Plant Molecular Biology</i>. Springer, 2002. <a href=\"https://doi.org/10.1023/A:1015248926412\">https://doi.org/10.1023/A:1015248926412</a>.","ieee":"J. Friml and K. Palme, “Polar auxin transport - Old questions and new concepts?,” <i>Plant Molecular Biology</i>, vol. 49, no. 3–4. Springer, pp. 273–284, 2002.","ama":"Friml J, Palme K. Polar auxin transport - Old questions and new concepts? <i>Plant Molecular Biology</i>. 2002;49(3-4):273-284. doi:<a href=\"https://doi.org/10.1023/A:1015248926412\">10.1023/A:1015248926412</a>"},"year":"2002","day":"01","oa_version":"None","type":"journal_article","date_updated":"2021-01-12T07:40:17Z","_id":"2991","language":[{"iso":"eng"}],"doi":"10.1023/A:1015248926412","publication":"Plant Molecular Biology","title":"Polar auxin transport - Old questions and new concepts?","abstract":[{"text":"Polar auxin transport controls multiple aspects of plant development including differential growth, embryo and root patterning and vascular tissue differentiation. Identification of proteins involved in this process and availability of new tools enabling `visualization' of auxin and auxin routes in planta largely contributed to the significant progress that has recently been made. New data support classical concepts, but several recent findings are likely to challenge our view on the mechanism of auxin transport. The aim of this review is to provide a comprehensive overview of the polar auxin transport field. It starts with classical models resulting from physiological studies, describes the genetic contributions and discusses the molecular basis of auxin influx and efflux. Finally, selected questions are presented in the context of developmental biology, integrating available data from different fields.","lang":"eng"}],"publication_status":"published","volume":49,"page":"273 - 284","issue":"3-4","date_published":"2002-06-01T00:00:00Z","publisher":"Springer","publist_id":"3712","intvolume":"        49","status":"public","month":"06","date_created":"2018-12-11T12:00:44Z"},{"page":"1035 - 1049","external_id":{"pmid":["12495620"]},"date_published":"2002-12-19T00:00:00Z","scopus_import":"1","publication_identifier":{"issn":["0896-6273"]},"user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","article_processing_charge":"No","day":"19","oa_version":"None","type":"journal_article","date_updated":"2023-07-17T11:46:43Z","language":[{"iso":"eng"}],"doi":"10.1016/S0896-6273(02)01101-7","acknowledgement":"We thank L. Role for generously providing the CRD-Nrg1 mutant allele for these studies, L. Parada and D. Anderson for sharing the TrkC and Ngn1 mouse strains, W. Tourtellotte for providing Egr3 mutant mice, E. Avetisova for expert technical assistance, X. Yang for experimental help in the initial phase of these studies, A. Garratt for advice with ErbB antibodies, and L. Role and G. Fischbach for helpful discussions. The CRD-Nrg1 mutant allele was generated in the lab of Dr. Lorna Role, with the support of NIH grant NS29071. S.A. and S.H. were supported by a grant from the Swiss National Science Foundation and the Kanton of Basel-Stadt. S.J.B. was supported by grants from the NINDS. N.A.S. was supported by a Howard Hughes Medical Institute Postdoctoral Fellowship for Physicians and a Career Development Award from the NINDS. T.M.J. was supported by grants from NINDS and is an Investigator of the Howard Hughes Medical Institute.","volume":36,"issue":"6","publisher":"Elsevier","article_type":"original","publist_id":"3558","intvolume":"        36","status":"public","month":"12","date_created":"2018-12-11T12:01:37Z","quality_controlled":"1","extern":"1","author":[{"first_name":"Simon","last_name":"Hippenmeyer","orcid":"0000-0003-2279-1061","full_name":"Hippenmeyer, Simon","id":"37B36620-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Shneider, Neil","last_name":"Shneider","first_name":"Neil"},{"full_name":"Birchmeier, Carmen","first_name":"Carmen","last_name":"Birchmeier"},{"full_name":"Burden, Steven","last_name":"Burden","first_name":"Steven"},{"full_name":"Jessell, Thomas","first_name":"Thomas","last_name":"Jessell"},{"full_name":"Arber, Silvia","last_name":"Arber","first_name":"Silvia"}],"citation":{"ama":"Hippenmeyer S, Shneider N, Birchmeier C, Burden S, Jessell T, Arber S. A role for Neuregulin1 signaling in muscle spindle differentiation. <i>Neuron</i>. 2002;36(6):1035-1049. doi:<a href=\"https://doi.org/10.1016/S0896-6273(02)01101-7\">10.1016/S0896-6273(02)01101-7</a>","ieee":"S. Hippenmeyer, N. Shneider, C. Birchmeier, S. Burden, T. Jessell, and S. Arber, “A role for Neuregulin1 signaling in muscle spindle differentiation,” <i>Neuron</i>, vol. 36, no. 6. Elsevier, pp. 1035–1049, 2002.","short":"S. Hippenmeyer, N. Shneider, C. Birchmeier, S. Burden, T. Jessell, S. Arber, Neuron 36 (2002) 1035–1049.","chicago":"Hippenmeyer, Simon, Neil Shneider, Carmen Birchmeier, Steven Burden, Thomas Jessell, and Silvia Arber. “A Role for Neuregulin1 Signaling in Muscle Spindle Differentiation.” <i>Neuron</i>. Elsevier, 2002. <a href=\"https://doi.org/10.1016/S0896-6273(02)01101-7\">https://doi.org/10.1016/S0896-6273(02)01101-7</a>.","ista":"Hippenmeyer S, Shneider N, Birchmeier C, Burden S, Jessell T, Arber S. 2002. A role for Neuregulin1 signaling in muscle spindle differentiation. Neuron. 36(6), 1035–1049.","apa":"Hippenmeyer, S., Shneider, N., Birchmeier, C., Burden, S., Jessell, T., &#38; Arber, S. (2002). A role for Neuregulin1 signaling in muscle spindle differentiation. <i>Neuron</i>. Elsevier. <a href=\"https://doi.org/10.1016/S0896-6273(02)01101-7\">https://doi.org/10.1016/S0896-6273(02)01101-7</a>","mla":"Hippenmeyer, Simon, et al. “A Role for Neuregulin1 Signaling in Muscle Spindle Differentiation.” <i>Neuron</i>, vol. 36, no. 6, Elsevier, 2002, pp. 1035–49, doi:<a href=\"https://doi.org/10.1016/S0896-6273(02)01101-7\">10.1016/S0896-6273(02)01101-7</a>."},"year":"2002","_id":"3140","pmid":1,"title":"A role for Neuregulin1 signaling in muscle spindle differentiation","publication":"Neuron","abstract":[{"lang":"eng","text":"The maturation of synaptic structures depends on inductive interactions between axons and their prospective targets. One example of such an interaction is the influence of proprioceptive sensory axons on the differentiation of muscle spindles. We have monitored the expression of three transcription factors, Egr3, Pea3, and Erm, that delineate early muscle spindle development in an assay of muscle spindle-inducing signals. We provide genetic evidence that Neuregulin1 (Nrg1) is required for proprioceptive afferent-evoked induction of muscle spindle differentiation in the mouse. Ig-Nrg1 isoforms are preferentially expressed by proprioceptive sensory neurons and are sufficient to induce muscle spindle differentiation in vivo, whereas CRD-Nrg1 isoforms are broadly expressed in sensory and motor neurons but are not required for muscle spindle induction."}],"publication_status":"published"},{"user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","article_processing_charge":"No","day":"01","type":"journal_article","date_updated":"2023-07-17T11:36:32Z","oa_version":"None","language":[{"iso":"eng"}],"doi":"10.1016/S0079-6107(02)00009-3","page":"1 - 43","date_published":"2002-05-01T00:00:00Z","external_id":{"pmid":["12225775"]},"publication_identifier":{"issn":["0079-6107"]},"scopus_import":"1","extern":"1","author":[{"first_name":"Daniel","last_name":"Mueller","full_name":"Mueller, Daniel"},{"orcid":"0000-0002-8023-9315","full_name":"Janovjak, Harald L","id":"33BA6C30-F248-11E8-B48F-1D18A9856A87","last_name":"Janovjak","first_name":"Harald L"},{"last_name":"Lehto","first_name":"Tiina","full_name":"Lehto, Tiina"},{"full_name":"Kuerschner, Lars","first_name":"Lars","last_name":"Kuerschner"},{"first_name":"Kurt","last_name":"Anderson","full_name":"Anderson, Kurt"}],"quality_controlled":"1","citation":{"ama":"Mueller D, Janovjak HL, Lehto T, Kuerschner L, Anderson K. Observing structure, function and assembly of single proteins by AFM. <i>Progress in Biophysics and Molecular Biology</i>. 2002;79(1-3):1-43. doi:<a href=\"https://doi.org/10.1016/S0079-6107(02)00009-3\">10.1016/S0079-6107(02)00009-3</a>","ieee":"D. Mueller, H. L. Janovjak, T. Lehto, L. Kuerschner, and K. Anderson, “Observing structure, function and assembly of single proteins by AFM,” <i>Progress in Biophysics and Molecular Biology</i>, vol. 79, no. 1–3. Elsevier, pp. 1–43, 2002.","short":"D. Mueller, H.L. Janovjak, T. Lehto, L. Kuerschner, K. Anderson, Progress in Biophysics and Molecular Biology 79 (2002) 1–43.","chicago":"Mueller, Daniel, Harald L Janovjak, Tiina Lehto, Lars Kuerschner, and Kurt Anderson. “Observing Structure, Function and Assembly of Single Proteins by AFM.” <i>Progress in Biophysics and Molecular Biology</i>. Elsevier, 2002. <a href=\"https://doi.org/10.1016/S0079-6107(02)00009-3\">https://doi.org/10.1016/S0079-6107(02)00009-3</a>.","ista":"Mueller D, Janovjak HL, Lehto T, Kuerschner L, Anderson K. 2002. Observing structure, function and assembly of single proteins by AFM. Progress in Biophysics and Molecular Biology. 79(1–3), 1–43.","apa":"Mueller, D., Janovjak, H. L., Lehto, T., Kuerschner, L., &#38; Anderson, K. (2002). Observing structure, function and assembly of single proteins by AFM. <i>Progress in Biophysics and Molecular Biology</i>. Elsevier. <a href=\"https://doi.org/10.1016/S0079-6107(02)00009-3\">https://doi.org/10.1016/S0079-6107(02)00009-3</a>","mla":"Mueller, Daniel, et al. “Observing Structure, Function and Assembly of Single Proteins by AFM.” <i>Progress in Biophysics and Molecular Biology</i>, vol. 79, no. 1–3, Elsevier, 2002, pp. 1–43, doi:<a href=\"https://doi.org/10.1016/S0079-6107(02)00009-3\">10.1016/S0079-6107(02)00009-3</a>."},"year":"2002","_id":"3421","publication":"Progress in Biophysics and Molecular Biology","title":"Observing structure, function and assembly of single proteins by AFM","pmid":1,"publication_status":"published","abstract":[{"text":"Single molecule experiments provide insight into the individuality of biological macromolecules, their unique function, reaction pathways, trajectories and molecular interactions. The exceptional signal-to-noise ratio of the atomic force microscope allows individual proteins to be imaged under physiologically relevant conditions at a lateral resolution of 0.5–1 nm and a vertical resolution of 0.1–0.2 nm. Recently, it has become possible to observe single molecule events using this technique. This capability is reviewed on various water-soluble and membrane proteins. Examples of the observation of function, variability, and assembly of single proteins are discussed. Statistical analysis is important to extend conclusions derived from single molecule experiments to protein species. Such approaches allow the classification of protein conformations and movements. Recent developments of probe microscopy techniques allow simultaneous measurement of multiple signals on individual macromolecules, and greatly extend the range of experiments possible for probing biological systems at the molecular level. Biologists exploring molecular mechanisms will benefit from a burgeoning of scanning probe microscopes and of their future combination with molecular biological experiments.","lang":"eng"}],"volume":79,"issue":"1-3","article_type":"review","publisher":"Elsevier","publist_id":"2980","intvolume":"        79","status":"public","date_created":"2018-12-11T12:03:14Z","month":"05"},{"page":"1372 - 1379","external_id":{"pmid":["12074169"]},"date_published":"2002-06-01T00:00:00Z","scopus_import":"1","publication_identifier":{"issn":["0736-6205"]},"day":"01","oa_version":"None","date_updated":"2023-07-17T11:29:06Z","type":"journal_article","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","article_processing_charge":"No","language":[{"iso":"eng"}],"publisher":"Informa Healthcare","article_type":"original","volume":32,"issue":"6","status":"public","month":"06","date_created":"2018-12-11T12:03:15Z","publist_id":"2979","intvolume":"        32","year":"2002","quality_controlled":"1","extern":"1","author":[{"full_name":"Müller, Patrick","first_name":"Patrick","last_name":"Müller"},{"first_name":"Harald L","last_name":"Janovjak","full_name":"Janovjak, Harald L","orcid":"0000-0002-8023-9315","id":"33BA6C30-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Miserez, Andre","first_name":"Andre","last_name":"Miserez"},{"full_name":"Dobbie, Zuzana","last_name":"Dobbie","first_name":"Zuzana"}],"citation":{"mla":"Müller, Patrick, et al. “Processing of Gene Expression Data Generated by Quantitative Real-Time RT-PCR.” <i>Biotechniques</i>, vol. 32, no. 6, Informa Healthcare, 2002, pp. 1372–79.","apa":"Müller, P., Janovjak, H. L., Miserez, A., &#38; Dobbie, Z. (2002). Processing of gene expression data generated by quantitative real-time RT-PCR. <i>Biotechniques</i>. Informa Healthcare.","ieee":"P. Müller, H. L. Janovjak, A. Miserez, and Z. Dobbie, “Processing of gene expression data generated by quantitative real-time RT-PCR,” <i>Biotechniques</i>, vol. 32, no. 6. Informa Healthcare, pp. 1372–1379, 2002.","ama":"Müller P, Janovjak HL, Miserez A, Dobbie Z. Processing of gene expression data generated by quantitative real-time RT-PCR. <i>Biotechniques</i>. 2002;32(6):1372-1379.","ista":"Müller P, Janovjak HL, Miserez A, Dobbie Z. 2002. Processing of gene expression data generated by quantitative real-time RT-PCR. Biotechniques. 32(6), 1372–1379.","short":"P. Müller, H.L. Janovjak, A. Miserez, Z. Dobbie, Biotechniques 32 (2002) 1372–1379.","chicago":"Müller, Patrick, Harald L Janovjak, Andre Miserez, and Zuzana Dobbie. “Processing of Gene Expression Data Generated by Quantitative Real-Time RT-PCR.” <i>Biotechniques</i>. Informa Healthcare, 2002."},"abstract":[{"text":"Quantitative real-time PCR represents a highly sensitive and powerful technique for the quantitation of nucleic acids. It has a tremendous potential for the high-throughput analysis of gene expression in research and routine diagnostics. However, the major hurdle is not the practical performance of the experiments themselves but rather the efficient evaluation and the mathematical and statistical analysis of the enormous amount of data gained by this technology, as these functions are not included in the software provided by the manufacturers of the detection systems. In this work, we focus on the mathematical evaluation and analysis of the data generated by quantitative real-time PCR, the calculation of the final results, the propagation of experimental variation of the measured values to the final results, and the statistical analysis. We developed a Microsoft Excel-based software application coded in Visual Basic for Applications, called Q-Gene, which addresses these points. Q-Gene manages and expedites the planning, performance, and evaluation of quantitative real-time PCR experiments, as well as the mathematical and statistical analysis, storage, and graphical presentation of the data. The Q-Gene software application is a tool to cope with complex quantitative real-time PCR experiments at a high-throughput scale and considerably expedites and rationalizes the experimental setup, data analysis, and data management while ensuring highest reproducibility.","lang":"eng"}],"publication_status":"published","_id":"3422","pmid":1,"title":"Processing of gene expression data generated by quantitative real-time RT-PCR","publication":"Biotechniques"},{"publist_id":"2978","status":"public","date_created":"2018-12-11T12:03:15Z","month":"01","conference":{"location":"Nassau, Bahamas","start_date":"2002-01-20","name":"Winter Workshop on Nuclear Dynamics","end_date":"2002-01-22"},"page":"111 - 118","date_published":"2002-01-01T00:00:00Z","publisher":"EP Systema","language":[{"iso":"eng"}],"_id":"3423","title":"The percolation interpretation of the nuclear fragmentation phase transition","publication":"Proceedings of the 18th Winter Workshop on Nuclear Dynamics","publication_status":"published","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","extern":"1","author":[{"last_name":"Bauer","first_name":"Wolfgang","full_name":"Bauer, Wolfgang"},{"id":"3E6DB97A-F248-11E8-B48F-1D18A9856A87","full_name":"Bollenbach, Mark Tobias","orcid":"0000-0003-4398-476X","last_name":"Bollenbach","first_name":"Mark Tobias"},{"full_name":"Kleine Berkenbusch, Marko","last_name":"Kleine Berkenbusch","first_name":"Marko"},{"first_name":"Holger","last_name":"Harreis","full_name":"Harreis, Holger"}],"article_processing_charge":"No","citation":{"mla":"Bauer, Wolfgang, et al. “The Percolation Interpretation of the Nuclear Fragmentation Phase Transition.” <i>Proceedings of the 18th Winter Workshop on Nuclear Dynamics</i>, EP Systema, 2002, pp. 111–18.","apa":"Bauer, W., Bollenbach, M. T., Kleine Berkenbusch, M., &#38; Harreis, H. (2002). The percolation interpretation of the nuclear fragmentation phase transition. In <i>Proceedings of the 18th Winter Workshop on Nuclear Dynamics</i> (pp. 111–118). Nassau, Bahamas: EP Systema.","short":"W. Bauer, M.T. Bollenbach, M. Kleine Berkenbusch, H. Harreis, in:, Proceedings of the 18th Winter Workshop on Nuclear Dynamics, EP Systema, 2002, pp. 111–118.","chicago":"Bauer, Wolfgang, Mark Tobias Bollenbach, Marko Kleine Berkenbusch, and Holger Harreis. “The Percolation Interpretation of the Nuclear Fragmentation Phase Transition.” In <i>Proceedings of the 18th Winter Workshop on Nuclear Dynamics</i>, 111–18. EP Systema, 2002.","ista":"Bauer W, Bollenbach MT, Kleine Berkenbusch M, Harreis H. 2002. The percolation interpretation of the nuclear fragmentation phase transition. Proceedings of the 18th Winter Workshop on Nuclear Dynamics. Winter Workshop on Nuclear Dynamics, 111–118.","ieee":"W. Bauer, M. T. Bollenbach, M. Kleine Berkenbusch, and H. Harreis, “The percolation interpretation of the nuclear fragmentation phase transition,” in <i>Proceedings of the 18th Winter Workshop on Nuclear Dynamics</i>, Nassau, Bahamas, 2002, pp. 111–118.","ama":"Bauer W, Bollenbach MT, Kleine Berkenbusch M, Harreis H. The percolation interpretation of the nuclear fragmentation phase transition. In: <i>Proceedings of the 18th Winter Workshop on Nuclear Dynamics</i>. EP Systema; 2002:111-118."},"day":"01","year":"2002","type":"conference","date_updated":"2023-07-17T11:15:14Z","oa_version":"None"},{"publist_id":"2977","publication_identifier":{"isbn":["9781510832008"]},"alternative_title":["Exotic Clustering, American Institute of Physics Conference Proceedings"],"intvolume":"       644","status":"public","month":"11","conference":{"name":"CRIS: Catania Relativistic Ion Studies ","end_date":"2002-06-14","start_date":"2002-06-10","location":"Catania, Italy"},"date_created":"2018-12-11T12:03:15Z","volume":644,"page":"219 - 232","date_published":"2002-11-26T00:00:00Z","publisher":"American Institute of Physics","_id":"3424","doi":"10.1063/1.1523196 ","language":[{"iso":"eng"}],"title":"3d supernovae collapse calculations","abstract":[{"lang":"eng","text":"We give a brief overview of the current understanding of the explosion mechanism of core collapse supernovae. Our main focus is the impact of rotation on the explosion. Recent observations of the polarization of the light emitted by supernova explosions indicate that there are large deviations from spherical symmetry in the very heart of the explosion the origin of which is unknown. We use the new approach of a three dimensional test particle based simulation to simulate the infall phase of a supernova event. The underlying microphysics is simplified to make this computationally possible. A systematic study of the influence of rotation mainly during the infall phase of the collapse of a typical iron core is performed. Indications for significant deviations from spherical symmetry are found in our very rapidly rotating models. © 2002 American Institute of Physics\r\n"}],"publication_status":"published","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","extern":"1","quality_controlled":"1","author":[{"orcid":"0000-0003-4398-476X","full_name":"Bollenbach, Mark Tobias","id":"3E6DB97A-F248-11E8-B48F-1D18A9856A87","first_name":"Mark Tobias","last_name":"Bollenbach"},{"first_name":"Wolfgang","last_name":"Bauer","full_name":"Bauer, Wolfgang"}],"article_processing_charge":"No","citation":{"ista":"Bollenbach MT, Bauer W. 2002. 3d supernovae collapse calculations. CRIS: Catania Relativistic Ion Studies , Exotic Clustering, American Institute of Physics Conference Proceedings, vol. 644, 219–232.","chicago":"Bollenbach, Mark Tobias, and Wolfgang Bauer. “3d Supernovae Collapse Calculations,” 644:219–32. American Institute of Physics, 2002. <a href=\"https://doi.org/10.1063/1.1523196 \">https://doi.org/10.1063/1.1523196 </a>.","short":"M.T. Bollenbach, W. Bauer, in:, American Institute of Physics, 2002, pp. 219–232.","ieee":"M. T. Bollenbach and W. Bauer, “3d supernovae collapse calculations,” presented at the CRIS: Catania Relativistic Ion Studies , Catania, Italy, 2002, vol. 644, pp. 219–232.","ama":"Bollenbach MT, Bauer W. 3d supernovae collapse calculations. In: Vol 644. American Institute of Physics; 2002:219-232. doi:<a href=\"https://doi.org/10.1063/1.1523196 \">10.1063/1.1523196 </a>","apa":"Bollenbach, M. T., &#38; Bauer, W. (2002). 3d supernovae collapse calculations (Vol. 644, pp. 219–232). Presented at the CRIS: Catania Relativistic Ion Studies , Catania, Italy: American Institute of Physics. <a href=\"https://doi.org/10.1063/1.1523196 \">https://doi.org/10.1063/1.1523196 </a>","mla":"Bollenbach, Mark Tobias, and Wolfgang Bauer. <i>3d Supernovae Collapse Calculations</i>. Vol. 644, American Institute of Physics, 2002, pp. 219–32, doi:<a href=\"https://doi.org/10.1063/1.1523196 \">10.1063/1.1523196 </a>."},"year":"2002","day":"26","oa_version":"None","date_updated":"2023-07-17T11:05:27Z","type":"conference"},{"publication_status":"published","_id":"3448","title":"Implementation of shape grammar for plan analysis","day":"15","year":"2002","type":"conference","date_updated":"2021-01-12T07:43:31Z","author":[{"first_name":"Sanhita","last_name":"Mallick","full_name":"Mallick, Sanhita"},{"first_name":"Krishnendu","last_name":"Chatterjee","full_name":"Krishnendu Chatterjee","orcid":"0000-0002-4561-241X","id":"2E5DCA20-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Merchant","first_name":"Arif","full_name":"Merchant, Arif N"},{"first_name":"Pallab","last_name":"Dasgupta","full_name":"Dasgupta, Pallab"}],"extern":1,"quality_controlled":0,"citation":{"ama":"Mallick S, Chatterjee K, Merchant A, Dasgupta P. Implementation of shape grammar for plan analysis. In: Elsevier; 2002.","ieee":"S. Mallick, K. Chatterjee, A. Merchant, and P. Dasgupta, “Implementation of shape grammar for plan analysis,” presented at the IT-Built: Information Technology For Built Environment, 2002.","ista":"Mallick S, Chatterjee K, Merchant A, Dasgupta P. 2002. Implementation of shape grammar for plan analysis. IT-Built: Information Technology For Built Environment.","short":"S. Mallick, K. Chatterjee, A. Merchant, P. Dasgupta, in:, Elsevier, 2002.","chicago":"Mallick, Sanhita, Krishnendu Chatterjee, Arif Merchant, and Pallab Dasgupta. “Implementation of Shape Grammar for Plan Analysis.” Elsevier, 2002.","apa":"Mallick, S., Chatterjee, K., Merchant, A., &#38; Dasgupta, P. (2002). Implementation of shape grammar for plan analysis. Presented at the IT-Built: Information Technology For Built Environment, Elsevier.","mla":"Mallick, Sanhita, et al. <i>Implementation of Shape Grammar for Plan Analysis</i>. Elsevier, 2002."},"status":"public","date_created":"2018-12-11T12:03:23Z","month":"01","conference":{"name":"IT-Built: Information Technology For Built Environment"},"publist_id":"2939","publisher":"Elsevier","date_published":"2002-01-15T00:00:00Z"},{"doi":"10.1007/s00424-001-0735-3","language":[{"iso":"eng"}],"acknowledgement":"We thank Dr. M. Frotscher for reading the manuscript, and H. Kressner, R. Laufersweiler, and A. Bühler for help with the construction of several prototypes of vibroslicer and vibroprobe. We also thank A. Blomenkamp, K. Winterhalter, B. Joch, and A. Schneider for technical assistance. This work was supported by grants of the Deutsche Forschungsgemeinschaft\r\n(SFB 505/C5, C6) and the Human Frontiers Science Program Organization (RG0017/1998-B).","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","article_processing_charge":"No","oa_version":"None","date_updated":"2023-07-17T07:36:37Z","type":"journal_article","day":"01","scopus_import":"1","publication_identifier":{"issn":["0031-6768"]},"external_id":{"pmid":["11810221"]},"date_published":"2002-01-01T00:00:00Z","page":"491 - 501","pmid":1,"title":"Patch-clamp recording in brain slices with improved slicer technology","publication":"Pflugers Archiv : European Journal of Physiology","_id":"3497","abstract":[{"lang":"eng","text":"The use of advanced patch-clamp recording techniques in brain slices, such as simultaneous recording from multiple neurons and recording from dendrites or presynaptic terminals, demands slices of the highest quality. In this context the mechanics of the tissue slicer are an important factor. Ideally, a tissue slicer should generate large-amplitude and high-frequency movements of the cutting blade in a horizontal axis, with minimal vibrations in the vertical axis. We developed a vibroslicer that fulfils these in part conflicting requirements. The oscillator is a permanent-magnet-coil-leaf-spring system. Using an auto-resonant mechano-electrical feedback circuit, large horizontal oscillations (up to 3 mm peak-to-peak) with high frequency (,90 Hz) are generated. To minimize vertical vibrations, an adjustment mechanism was employed that allowed alignment of the cutting edge of the blade with the major axis of the oscillation. A vibroprobe device was used to monitor vertical vibrations during adjustment. The system is based on the shading of the light path between a light-emitting diode (LED) and a photodiode. Vibroprobe monitoring revealed that the vibroslicer, after appropriate adjustment, generated vertical vibrations of &lt;1 µm, significantly less than many commercial tissue slicers. Light- and electron-microscopic analysis of surface layers of slices cut with the vibroslicer showed that cellular elements, dendritic processes and presynaptic terminals are well preserved under these conditions, as required for patch-clamp recording from these structures."}],"publication_status":"published","citation":{"apa":"Geiger, J., Bischofberger, J., Vida, I., Fröbe, U., Pfitzinger, S., Weber, H., … Jonas, P. M. (2002). Patch-clamp recording in brain slices with improved slicer technology. <i>Pflugers Archiv : European Journal of Physiology</i>. Springer. <a href=\"https://doi.org/10.1007/s00424-001-0735-3\">https://doi.org/10.1007/s00424-001-0735-3</a>","mla":"Geiger, Jörg, et al. “Patch-Clamp Recording in Brain Slices with Improved Slicer Technology.” <i>Pflugers Archiv : European Journal of Physiology</i>, vol. 443, no. 3, Springer, 2002, pp. 491–501, doi:<a href=\"https://doi.org/10.1007/s00424-001-0735-3\">10.1007/s00424-001-0735-3</a>.","ista":"Geiger J, Bischofberger J, Vida I, Fröbe U, Pfitzinger S, Weber H, Haverkampf K, Jonas PM. 2002. Patch-clamp recording in brain slices with improved slicer technology. Pflugers Archiv : European Journal of Physiology. 443(3), 491–501.","short":"J. Geiger, J. Bischofberger, I. Vida, U. Fröbe, S. Pfitzinger, H. Weber, K. Haverkampf, P.M. Jonas, Pflugers Archiv : European Journal of Physiology 443 (2002) 491–501.","chicago":"Geiger, Jörg, Joseph Bischofberger, Imre Vida, Ulrich Fröbe, S Pfitzinger, H. Weber, Klaus Haverkampf, and Peter M Jonas. “Patch-Clamp Recording in Brain Slices with Improved Slicer Technology.” <i>Pflugers Archiv : European Journal of Physiology</i>. Springer, 2002. <a href=\"https://doi.org/10.1007/s00424-001-0735-3\">https://doi.org/10.1007/s00424-001-0735-3</a>.","ama":"Geiger J, Bischofberger J, Vida I, et al. Patch-clamp recording in brain slices with improved slicer technology. <i>Pflugers Archiv : European Journal of Physiology</i>. 2002;443(3):491-501. doi:<a href=\"https://doi.org/10.1007/s00424-001-0735-3\">10.1007/s00424-001-0735-3</a>","ieee":"J. Geiger <i>et al.</i>, “Patch-clamp recording in brain slices with improved slicer technology,” <i>Pflugers Archiv : European Journal of Physiology</i>, vol. 443, no. 3. Springer, pp. 491–501, 2002."},"quality_controlled":"1","extern":"1","author":[{"full_name":"Geiger, Jörg","last_name":"Geiger","first_name":"Jörg"},{"first_name":"Joseph","last_name":"Bischofberger","full_name":"Bischofberger, Joseph"},{"last_name":"Vida","first_name":"Imre","full_name":"Vida, Imre"},{"full_name":"Fröbe, Ulrich","last_name":"Fröbe","first_name":"Ulrich"},{"first_name":"S","last_name":"Pfitzinger","full_name":"Pfitzinger, S"},{"full_name":"Weber, H.","first_name":"H.","last_name":"Weber"},{"full_name":"Haverkampf, Klaus","last_name":"Haverkampf","first_name":"Klaus"},{"id":"353C1B58-F248-11E8-B48F-1D18A9856A87","full_name":"Jonas, Peter M","orcid":"0000-0001-5001-4804","first_name":"Peter M","last_name":"Jonas"}],"year":"2002","intvolume":"       443","publist_id":"2890","month":"01","date_created":"2018-12-11T12:03:38Z","status":"public","volume":443,"issue":"3","publisher":"Springer","article_type":"original"},{"title":"Methods of generating three-dimensional digital models of objects by wrapping point cloud data points","_id":"3508","oa":1,"abstract":[{"lang":"eng","text":"A method of automatic conversion of a physical object into a three-dimensional digital model. The method acquires a set of measured data points on the surface of a physical model. From the measured data points, the method reconstructs a digital model of the physical object using a Delaunay complex of the points, a flow strcuture of the simplicies in the Delaunay complex and retracting the Delaunay complex into a digital model of the physical object using the flow structure. The method then outputs the digital model of the physical object."}],"applicant":["Raindrop Geomagic, Inc."],"citation":{"ista":"Edelsbrunner H, Fu P. 2002. Methods of generating three-dimensional digital models of objects by wrapping point cloud data points.","short":"H. Edelsbrunner, P. Fu, (2002).","chicago":"Edelsbrunner, Herbert, and Ping Fu. “Methods of Generating Three-Dimensional Digital Models of Objects by Wrapping Point Cloud Data Points,” 2002.","ieee":"H. Edelsbrunner and P. Fu, “Methods of generating three-dimensional digital models of objects by wrapping point cloud data points.” 2002.","ama":"Edelsbrunner H, Fu P. Methods of generating three-dimensional digital models of objects by wrapping point cloud data points. 2002.","mla":"Edelsbrunner, Herbert, and Ping Fu. <i>Methods of Generating Three-Dimensional Digital Models of Objects by Wrapping Point Cloud Data Points</i>. 2002.","apa":"Edelsbrunner, H., &#38; Fu, P. (2002). Methods of generating three-dimensional digital models of objects by wrapping point cloud data points."},"main_file_link":[{"url":"https://patents.google.com/patent/US6377865B1","open_access":"1"}],"ipc":"G16Z99/00 ; G06K9/28 ; G06T17/10 ; G06T17/20","extern":"1","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","author":[{"first_name":"Herbert","last_name":"Edelsbrunner","full_name":"Edelsbrunner, Herbert","orcid":"0000-0002-9823-6833","id":"3FB178DA-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Ping","last_name":"Fu","full_name":"Fu, Ping"}],"article_processing_charge":"No","oa_version":"Published Version","type":"patent","date_updated":"2022-01-05T14:09:36Z","year":"2002","ipn":"US6377865B1","day":"23","publist_id":"2879","month":"04","date_created":"2018-12-11T12:03:42Z","status":"public","date_published":"2002-04-23T00:00:00Z","publication_date":"2002-04-23"},{"publication_identifier":{"issn":["1047-3211"]},"scopus_import":"1","date_published":"2002-09-01T00:00:00Z","external_id":{"pmid":["12183388"]},"page":"893 - 899","language":[{"iso":"eng"}],"doi":"10.1093/cercor/12.9.893","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","article_processing_charge":"No","date_updated":"2023-07-17T07:27:12Z","type":"journal_article","oa_version":"None","day":"01","intvolume":"        12","publist_id":"2851","date_created":"2018-12-11T12:03:50Z","month":"09","status":"public","volume":12,"issue":"9","publisher":"Oxford University Press","article_type":"original","publication":"Cerebral Cortex","title":"Homeostatic maintenance of neuronal excitability by burst discharges in vivo","pmid":1,"_id":"3533","publication_status":"published","abstract":[{"lang":"eng","text":"Information in neuronal networks is thought to be represented by the rate of discharge and the temporal relationship between the discharging neurons. The discharge frequency of neurons is affected by their afferents and intrinsic properties, and shows great individual variability. The temporal coordination of neurons is greatly facilitated by network oscillations. In the hippocampus, population synchrony fluctuates during theta and gamma oscillations (10-100 ms scale) and can increase almost 10-fold during sharp wave bursts. Despite these large changes in excitability in the sub-second scale, longer-term (minute-scale) firing rates of individual neurons are relatively constant in an unchanging environment. As a result, mean hippocampal output remains stable over time. To understand the mechanisms responsible for this homeostasis, we address the following issues: (i) Can firing rates of single cells be modified? (ii) Once modified, what mechanism(s) can maintain the changes? We show that firing rates of hippocampal pyramidal cells can be altered in a novel environment and by Hebbian pairing of physiological input patterns with postsynaptic burst discharge. We also illustrate a competition between single spikes and the occurrence of spike bursts. Since spike-inducing (suprathreshold) inputs decrease the ability of strong ('teaching') inputs to induce a burst discharge, we propose that the single spike versus burst competition presents a homeostatic regulatory mechanism to maintain synaptic strength and, consequently, firing rate in pyramidal cells."}],"citation":{"apa":"Buzsáki, G., Csicsvari, J. L., Dragoi, G., Harris, K., Henze, D., &#38; Hirase, H. (2002). Homeostatic maintenance of neuronal excitability by burst discharges in vivo. <i>Cerebral Cortex</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/cercor/12.9.893\">https://doi.org/10.1093/cercor/12.9.893</a>","mla":"Buzsáki, György, et al. “Homeostatic Maintenance of Neuronal Excitability by Burst Discharges in Vivo.” <i>Cerebral Cortex</i>, vol. 12, no. 9, Oxford University Press, 2002, pp. 893–99, doi:<a href=\"https://doi.org/10.1093/cercor/12.9.893\">10.1093/cercor/12.9.893</a>.","short":"G. Buzsáki, J.L. Csicsvari, G. Dragoi, K. Harris, D. Henze, H. Hirase, Cerebral Cortex 12 (2002) 893–899.","chicago":"Buzsáki, György, Jozsef L Csicsvari, George Dragoi, Kenneth Harris, D. Henze, and Hajima Hirase. “Homeostatic Maintenance of Neuronal Excitability by Burst Discharges in Vivo.” <i>Cerebral Cortex</i>. Oxford University Press, 2002. <a href=\"https://doi.org/10.1093/cercor/12.9.893\">https://doi.org/10.1093/cercor/12.9.893</a>.","ista":"Buzsáki G, Csicsvari JL, Dragoi G, Harris K, Henze D, Hirase H. 2002. Homeostatic maintenance of neuronal excitability by burst discharges in vivo. Cerebral Cortex. 12(9), 893–899.","ieee":"G. Buzsáki, J. L. Csicsvari, G. Dragoi, K. Harris, D. Henze, and H. Hirase, “Homeostatic maintenance of neuronal excitability by burst discharges in vivo,” <i>Cerebral Cortex</i>, vol. 12, no. 9. Oxford University Press, pp. 893–899, 2002.","ama":"Buzsáki G, Csicsvari JL, Dragoi G, Harris K, Henze D, Hirase H. Homeostatic maintenance of neuronal excitability by burst discharges in vivo. <i>Cerebral Cortex</i>. 2002;12(9):893-899. doi:<a href=\"https://doi.org/10.1093/cercor/12.9.893\">10.1093/cercor/12.9.893</a>"},"quality_controlled":"1","author":[{"last_name":"Buzsáki","first_name":"György","full_name":"Buzsáki, György"},{"last_name":"Csicsvari","first_name":"Jozsef L","id":"3FA14672-F248-11E8-B48F-1D18A9856A87","full_name":"Csicsvari, Jozsef L","orcid":"0000-0002-5193-4036"},{"full_name":"Dragoi, George","first_name":"George","last_name":"Dragoi"},{"full_name":"Harris, Kenneth","first_name":"Kenneth","last_name":"Harris"},{"first_name":"D.","last_name":"Henze","full_name":"Henze, D."},{"last_name":"Hirase","first_name":"Hajima","full_name":"Hirase, Hajima"}],"extern":"1","year":"2002"},{"intvolume":"       161","publist_id":"2762","date_created":"2018-12-11T12:04:17Z","month":"08","status":"public","issue":"4","volume":161,"publisher":"Genetics Society of America","article_type":"original","publication":"Genetics","title":"General models of multilocus evolution","pmid":1,"oa":1,"_id":"3621","publication_status":"published","abstract":[{"text":"In 1991, Barton and Turelli developed recursions to describe the evolution of multilocus systems under arbitrary forms of selection. This article generalizes their approach to allow for arbitrary modes of inheritance, including diploidy, polyploidy, sex linkage, cytoplasmic inheritance, and genomic imprinting. The framework is also extended to allow for other deterministic evolutionary forces, including migration and mutation. Exact recursions that fully describe the state of the population are presented; these are implemented in a computer algebra package (available on the Web at http://helios.bto.ed.ac.uk/evolgen). Despite the generality of our framework, it can describe evolutionary dynamics exactly by just two equations. These recursions can be further simplified using a &quot;quasi-linkage equilibrium&quot; (QLE) approximation. We illustrate the methods by finding the effect of natural selection, sexual selection, mutation, and migration on the genetic composition of a population.","lang":"eng"}],"main_file_link":[{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462196/","open_access":"1"}],"citation":{"ama":"Kirkpatrick M, Johnson T, Barton NH. General models of multilocus evolution. <i>Genetics</i>. 2002;161(4):1727-1750. doi:<a href=\"https://doi.org/10.1093/genetics/161.4.1727\">10.1093/genetics/161.4.1727</a>","ieee":"M. Kirkpatrick, T. Johnson, and N. H. Barton, “General models of multilocus evolution,” <i>Genetics</i>, vol. 161, no. 4. Genetics Society of America, pp. 1727–1750, 2002.","ista":"Kirkpatrick M, Johnson T, Barton NH. 2002. General models of multilocus evolution. Genetics. 161(4), 1727–1750.","chicago":"Kirkpatrick, Mark, Toby Johnson, and Nicholas H Barton. “General Models of Multilocus Evolution.” <i>Genetics</i>. Genetics Society of America, 2002. <a href=\"https://doi.org/10.1093/genetics/161.4.1727\">https://doi.org/10.1093/genetics/161.4.1727</a>.","short":"M. Kirkpatrick, T. Johnson, N.H. Barton, Genetics 161 (2002) 1727–1750.","mla":"Kirkpatrick, Mark, et al. “General Models of Multilocus Evolution.” <i>Genetics</i>, vol. 161, no. 4, Genetics Society of America, 2002, pp. 1727–50, doi:<a href=\"https://doi.org/10.1093/genetics/161.4.1727\">10.1093/genetics/161.4.1727</a>.","apa":"Kirkpatrick, M., Johnson, T., &#38; Barton, N. H. (2002). General models of multilocus evolution. <i>Genetics</i>. Genetics Society of America. <a href=\"https://doi.org/10.1093/genetics/161.4.1727\">https://doi.org/10.1093/genetics/161.4.1727</a>"},"quality_controlled":"1","author":[{"full_name":"Kirkpatrick, Mark","first_name":"Mark","last_name":"Kirkpatrick"},{"full_name":"Johnson, Toby","first_name":"Toby","last_name":"Johnson"},{"last_name":"Barton","first_name":"Nicholas H","full_name":"Barton, Nicholas H","orcid":"0000-0002-8548-5240","id":"4880FE40-F248-11E8-B48F-1D18A9856A87"}],"extern":"1","year":"2002","publication_identifier":{"issn":["0016-6731"]},"scopus_import":"1","date_published":"2002-08-01T00:00:00Z","external_id":{"pmid":["12196414"]},"page":"1727 - 1750","language":[{"iso":"eng"}],"doi":"10.1093/genetics/161.4.1727","article_processing_charge":"No","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","date_updated":"2023-07-11T13:20:26Z","type":"journal_article","oa_version":"Published Version","day":"01"},{"scopus_import":"1","publication_identifier":{"issn":["0036-8075"]},"page":"1466 - 1470","external_id":{"pmid":["12029133"]},"date_published":"2002-05-24T00:00:00Z","language":[{"iso":"eng"}],"doi":"10.1126/science.1067407","article_processing_charge":"No","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","day":"24","oa_version":"None","date_updated":"2023-07-11T12:48:53Z","type":"journal_article","publist_id":"2471","intvolume":"       296","status":"public","month":"05","date_created":"2018-12-11T12:05:00Z","volume":296,"issue":"5572","article_type":"original","publisher":"American Association for the Advancement of Science","_id":"3757","pmid":1,"publication":"Science","title":"Combinatorial synthesis of genetic networks","abstract":[{"text":"A central problem in biology is determining how genes interact as parts of functional networks. Creation and analysis of synthetic networks, composed of well-characterized genetic elements, provide a framework for theoretical modeling. Here, with the use of a combinatorial method, a library of networks with varying connectivity was generated in Escherichia coli. These networks were composed of genes encoding the transcriptional regulators Lacl, TetR, and lambda Cl, as well as the corresponding promoters. They displayed phenotypic behaviors resembling binary logical circuits, with two chemical “inputs” and a fluorescent protein “output.” Within this simple system, diverse computational functions arose through changes in network connectivity. Combinatorial synthesis provides an alternative approach for studying biological networks, as well as an efficient method for producing diverse phenotypes in vivo.","lang":"eng"}],"publication_status":"published","extern":"1","quality_controlled":"1","author":[{"id":"47F8433E-F248-11E8-B48F-1D18A9856A87","full_name":"Guet, Calin C","orcid":"0000-0001-6220-2052","last_name":"Guet","first_name":"Calin C"},{"full_name":"Elowitz, Michael","last_name":"Elowitz","first_name":"Michael"},{"last_name":"Hsing","first_name":"Weihong","full_name":"Hsing, Weihong"},{"first_name":"Stanislas","last_name":"Leibler","full_name":"Leibler, Stanislas"}],"citation":{"mla":"Guet, Calin C., et al. “Combinatorial Synthesis of Genetic Networks.” <i>Science</i>, vol. 296, no. 5572, American Association for the Advancement of Science, 2002, pp. 1466–70, doi:<a href=\"https://doi.org/10.1126/science.1067407\">10.1126/science.1067407</a>.","apa":"Guet, C. C., Elowitz, M., Hsing, W., &#38; Leibler, S. (2002). Combinatorial synthesis of genetic networks. <i>Science</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/science.1067407\">https://doi.org/10.1126/science.1067407</a>","ista":"Guet CC, Elowitz M, Hsing W, Leibler S. 2002. Combinatorial synthesis of genetic networks. Science. 296(5572), 1466–1470.","chicago":"Guet, Calin C, Michael Elowitz, Weihong Hsing, and Stanislas Leibler. “Combinatorial Synthesis of Genetic Networks.” <i>Science</i>. American Association for the Advancement of Science, 2002. <a href=\"https://doi.org/10.1126/science.1067407\">https://doi.org/10.1126/science.1067407</a>.","short":"C.C. Guet, M. Elowitz, W. Hsing, S. Leibler, Science 296 (2002) 1466–1470.","ieee":"C. C. Guet, M. Elowitz, W. Hsing, and S. Leibler, “Combinatorial synthesis of genetic networks,” <i>Science</i>, vol. 296, no. 5572. American Association for the Advancement of Science, pp. 1466–1470, 2002.","ama":"Guet CC, Elowitz M, Hsing W, Leibler S. Combinatorial synthesis of genetic networks. <i>Science</i>. 2002;296(5572):1466-1470. doi:<a href=\"https://doi.org/10.1126/science.1067407\">10.1126/science.1067407</a>"},"year":"2002"}]