[{"issue":"6","volume":277,"article_type":"original","publisher":"Elsevier","file_date_updated":"2023-08-01T12:44:09Z","intvolume":"       277","status":"public","date_created":"2023-08-01T12:37:50Z","month":"02","quality_controlled":"1","extern":"1","author":[{"full_name":"Fürst, Johannes","last_name":"Fürst","first_name":"Johannes"},{"full_name":"Ritter, Markus","last_name":"Ritter","first_name":"Markus"},{"last_name":"Rudzki","first_name":"Jakob","full_name":"Rudzki, Jakob"},{"id":"42EFD3B6-F248-11E8-B48F-1D18A9856A87","full_name":"Danzl, Johann G","orcid":"0000-0001-8559-3973","first_name":"Johann G","last_name":"Danzl"},{"last_name":"Gschwentner","first_name":"Martin","full_name":"Gschwentner, Martin"},{"first_name":"Elke","last_name":"Scandella","full_name":"Scandella, Elke"},{"full_name":"Jakab, Martin","first_name":"Martin","last_name":"Jakab"},{"full_name":"König, Matthias","first_name":"Matthias","last_name":"König"},{"first_name":"Bernhard","last_name":"Oehl","full_name":"Oehl, Bernhard"},{"full_name":"Lang, Florian","last_name":"Lang","first_name":"Florian"},{"full_name":"Deetjen, Peter","last_name":"Deetjen","first_name":"Peter"},{"last_name":"Paulmichl","first_name":"Markus","full_name":"Paulmichl, Markus"}],"citation":{"ama":"Fürst J, Ritter M, Rudzki J, et al. ICln Ion channel splice variants in Caenorhabditis elegans. <i>Journal of Biological Chemistry</i>. 2002;277(6):4435-4445. doi:<a href=\"https://doi.org/10.1074/jbc.m107372200\">10.1074/jbc.m107372200</a>","ieee":"J. Fürst <i>et al.</i>, “ICln Ion channel splice variants in Caenorhabditis elegans,” <i>Journal of Biological Chemistry</i>, vol. 277, no. 6. Elsevier, pp. 4435–4445, 2002.","ista":"Fürst J, Ritter M, Rudzki J, Danzl JG, Gschwentner M, Scandella E, Jakab M, König M, Oehl B, Lang F, Deetjen P, Paulmichl M. 2002. ICln Ion channel splice variants in Caenorhabditis elegans. Journal of Biological Chemistry. 277(6), 4435–4445.","short":"J. Fürst, M. Ritter, J. Rudzki, J.G. Danzl, M. Gschwentner, E. Scandella, M. Jakab, M. König, B. Oehl, F. Lang, P. Deetjen, M. Paulmichl, Journal of Biological Chemistry 277 (2002) 4435–4445.","chicago":"Fürst, Johannes, Markus Ritter, Jakob Rudzki, Johann G Danzl, Martin Gschwentner, Elke Scandella, Martin Jakab, et al. “ICln Ion Channel Splice Variants in Caenorhabditis Elegans.” <i>Journal of Biological Chemistry</i>. Elsevier, 2002. <a href=\"https://doi.org/10.1074/jbc.m107372200\">https://doi.org/10.1074/jbc.m107372200</a>.","mla":"Fürst, Johannes, et al. “ICln Ion Channel Splice Variants in Caenorhabditis Elegans.” <i>Journal of Biological Chemistry</i>, vol. 277, no. 6, Elsevier, 2002, pp. 4435–45, doi:<a href=\"https://doi.org/10.1074/jbc.m107372200\">10.1074/jbc.m107372200</a>.","apa":"Fürst, J., Ritter, M., Rudzki, J., Danzl, J. G., Gschwentner, M., Scandella, E., … Paulmichl, M. (2002). ICln Ion channel splice variants in Caenorhabditis elegans. <i>Journal of Biological Chemistry</i>. Elsevier. <a href=\"https://doi.org/10.1074/jbc.m107372200\">https://doi.org/10.1074/jbc.m107372200</a>"},"year":"2002","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"ddc":["570"],"oa":1,"_id":"13438","publication":"Journal of Biological Chemistry","title":"ICln Ion channel splice variants in Caenorhabditis elegans","pmid":1,"publication_status":"published","abstract":[{"text":"ICln is an ion channel identified by expression cloning using a cDNA library from Madin-Darby canine kidney cells. In all organisms tested so far, only one transcript for the ICln protein could be identified. Here we show that two splice variants of the ICln ion channel can be found in Caenorhabditis elegans. Moreover, we show that these two splice variants of the ICln channel protein, which we termed IClnN1 and IClnN2, can be functionally reconstituted and tested in an artificial lipid bilayer. In these experiments, the IClnN1-induced currents showed no voltage-dependent inactivation, whereas the IClnN2-induced currents fully inactivated at positive potentials. The molecular entity responsible for the voltage-dependent inactivation of IClnN2 is a cluster of positively charged amino acids encoded by exon 2a, which is absent in IClnN1. Our experiments suggest a mechanism of channel inactivation that is similar to the “ball and chain” model proposed for the Shaker potassium channel,i.e. a cluster of positively charged amino acids hinders ion permeation through the channel by a molecular and voltage-dependent interaction at the inner vestibulum of the pore. This hypothesis is supported by the finding that synthetic peptides with the same amino acid sequence as the positive cluster can transform the IClnN1-induced current to the current observed after reconstitution of IClnN2. Furthermore, we show that the nematode ICln gene is embedded in an operon harboring two additional genes, which we termed Nx and Ny. Co-reconstitution of Nx and IClnN2 and functional analysis of the related currents revealed a functional interaction between the two proteins, as evidenced by the fact that the IClnN2-induced current in the presence of Nx was no longer voltage-sensitive. The experiments described indicate that the genome organization in nematodes allows an effective approach for the identification of functional partner proteins of ion channels.","lang":"eng"}],"page":"4435-4445","date_published":"2002-02-08T00:00:00Z","keyword":["Cell Biology","Molecular Biology","Biochemistry"],"external_id":{"pmid":["11706026"]},"file":[{"content_type":"application/pdf","creator":"alisjak","file_size":798920,"date_created":"2023-08-01T12:44:09Z","relation":"main_file","access_level":"open_access","checksum":"13abe20f78eb37ab62beb006f62c69b7","file_name":"2002_JBC_Fuerst.pdf","file_id":"13439","date_updated":"2023-08-01T12:44:09Z","success":1}],"publication_identifier":{"issn":["0021-9258"]},"scopus_import":"1","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","article_processing_charge":"No","day":"08","type":"journal_article","date_updated":"2023-08-01T12:55:54Z","oa_version":"Published Version","language":[{"iso":"eng"}],"doi":"10.1074/jbc.m107372200","has_accepted_license":"1","acknowledgement":"We are grateful to D. E. Clapham, E. Wöll, G. Meyer, and G. Botta for helpful discussion and/or reading of the manuscript. We also thank T. Stiernagle for providing the N2 strain of C. elegans and A. Wimmer and M. Frick for technical assistance"},{"arxiv":1,"scopus_import":"1","publication_identifier":{"issn":["1431-0635"]},"external_id":{"arxiv":["math/0203096"]},"date_published":"2002-01-01T00:00:00Z","page":"495 - 534","acknowledgement":"Both authors were supported by the Miller Institute for Basic Research in Science, in the form of a Miller Research Fellowship (1999-2002) for the first author and a Miller Professorship (2000-2001) for the second author. The second author was also supported by the National Science\r\nFoundation (DMS-9970254).","language":[{"iso":"eng"}],"doi":"10.4171/DM/130","oa_version":"Published Version","date_updated":"2023-07-26T09:16:33Z","type":"journal_article","day":"01","article_processing_charge":"No","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","month":"01","date_created":"2018-12-11T11:52:06Z","status":"public","intvolume":"         7","publist_id":"5741","article_type":"original","publisher":"Deutsche Mathematiker Vereinigung","volume":7,"issue":"1","abstract":[{"text":"Extending work of Bielawski-Dancer 3 and Konno 14, we develop a theory of toric hyperkähler varieties, which involves toric geometry, matroid theory and convex polyhedra. The framework is a detailed study of semi-projective toric varieties, meaning GIT quotients of affine spaces by torus actions, and specifically, of Lawrence toric varieties, meaning GIT quotients of even-dimensional affine spaces by symplectic torus actions. A toric hyperkähler variety is a complete intersection in a Lawrence toric variety. Both varieties are non-compact, and they share the same cohomology ring, namely, the Stanley-Reisner ring of a matroid modulo a linear system of parameters. Familiar applications of toric geometry to combinatorics, including the Hard Lefschetz Theorem and the volume polynomials of Khovanskii-Pukhlikov 11, are extended to the hyperkähler setting. When the matroid is graphic, our construction gives the toric quiver varieties, in the sense of Nakajima 17.","lang":"eng"}],"publication_status":"published","title":"Toric hyperkähler varieties","publication":"Documenta Mathematica","_id":"1451","oa":1,"year":"2002","citation":{"apa":"Hausel, T., &#38; Sturmfels, B. (2002). Toric hyperkähler varieties. <i>Documenta Mathematica</i>. Deutsche Mathematiker Vereinigung. <a href=\"https://doi.org/10.4171/DM/130\">https://doi.org/10.4171/DM/130</a>","mla":"Hausel, Tamás, and Bernd Sturmfels. “Toric Hyperkähler Varieties.” <i>Documenta Mathematica</i>, vol. 7, no. 1, Deutsche Mathematiker Vereinigung, 2002, pp. 495–534, doi:<a href=\"https://doi.org/10.4171/DM/130\">10.4171/DM/130</a>.","ama":"Hausel T, Sturmfels B. Toric hyperkähler varieties. <i>Documenta Mathematica</i>. 2002;7(1):495-534. doi:<a href=\"https://doi.org/10.4171/DM/130\">10.4171/DM/130</a>","ieee":"T. Hausel and B. Sturmfels, “Toric hyperkähler varieties,” <i>Documenta Mathematica</i>, vol. 7, no. 1. Deutsche Mathematiker Vereinigung, pp. 495–534, 2002.","chicago":"Hausel, Tamás, and Bernd Sturmfels. “Toric Hyperkähler Varieties.” <i>Documenta Mathematica</i>. Deutsche Mathematiker Vereinigung, 2002. <a href=\"https://doi.org/10.4171/DM/130\">https://doi.org/10.4171/DM/130</a>.","short":"T. Hausel, B. Sturmfels, Documenta Mathematica 7 (2002) 495–534.","ista":"Hausel T, Sturmfels B. 2002. Toric hyperkähler varieties. Documenta Mathematica. 7(1), 495–534."},"main_file_link":[{"url":"https://ems.press/journals/dm/articles/8965058","open_access":"1"}],"extern":"1","quality_controlled":"1","author":[{"first_name":"Tamas","last_name":"Hausel","full_name":"Hausel, Tamas","id":"4A0666D8-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Sturmfels, Bernd","first_name":"Bernd","last_name":"Sturmfels"}]},{"page":"925-929","issue":"6910","volume":419,"external_id":{"pmid":["12410311"]},"date_published":"2002-10-31T00:00:00Z","publisher":"Springer Nature","publication_identifier":{"issn":["0028-0836"]},"intvolume":"       419","status":"public","month":"10","date_created":"2019-03-21T10:09:20Z","extern":"1","author":[{"full_name":"Coates, Juliet C.","first_name":"Juliet C.","last_name":"Coates"},{"last_name":"de Bono","first_name":"Mario","id":"4E3FF80E-F248-11E8-B48F-1D18A9856A87","full_name":"de Bono, Mario","orcid":"0000-0001-8347-0443"}],"quality_controlled":"1","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","citation":{"apa":"Coates, J. C., &#38; de Bono, M. (2002). Antagonistic pathways in neurons exposed to body fluid regulate social feeding in Caenorhabditis elegans. <i>Nature</i>. Springer Nature. <a href=\"https://doi.org/10.1038/nature01170\">https://doi.org/10.1038/nature01170</a>","mla":"Coates, Juliet C., and Mario de Bono. “Antagonistic Pathways in Neurons Exposed to Body Fluid Regulate Social Feeding in Caenorhabditis Elegans.” <i>Nature</i>, vol. 419, no. 6910, Springer Nature, 2002, pp. 925–29, doi:<a href=\"https://doi.org/10.1038/nature01170\">10.1038/nature01170</a>.","chicago":"Coates, Juliet C., and Mario de Bono. “Antagonistic Pathways in Neurons Exposed to Body Fluid Regulate Social Feeding in Caenorhabditis Elegans.” <i>Nature</i>. Springer Nature, 2002. <a href=\"https://doi.org/10.1038/nature01170\">https://doi.org/10.1038/nature01170</a>.","short":"J.C. Coates, M. de Bono, Nature 419 (2002) 925–929.","ista":"Coates JC, de Bono M. 2002. Antagonistic pathways in neurons exposed to body fluid regulate social feeding in Caenorhabditis elegans. Nature. 419(6910), 925–929.","ieee":"J. C. Coates and M. de Bono, “Antagonistic pathways in neurons exposed to body fluid regulate social feeding in Caenorhabditis elegans,” <i>Nature</i>, vol. 419, no. 6910. Springer Nature, pp. 925–929, 2002.","ama":"Coates JC, de Bono M. Antagonistic pathways in neurons exposed to body fluid regulate social feeding in Caenorhabditis elegans. <i>Nature</i>. 2002;419(6910):925-929. doi:<a href=\"https://doi.org/10.1038/nature01170\">10.1038/nature01170</a>"},"year":"2002","day":"31","oa_version":"None","type":"journal_article","date_updated":"2021-01-12T08:06:26Z","_id":"6158","doi":"10.1038/nature01170","language":[{"iso":"eng"}],"pmid":1,"publication":"Nature","title":"Antagonistic pathways in neurons exposed to body fluid regulate social feeding in Caenorhabditis elegans","abstract":[{"lang":"eng","text":"Wild isolates of Caenorhabditis elegans can feed either alone or in groups1,2. This natural variation in behaviour is associated with a single residue difference in NPR-1, a predicted G-protein-coupled neuropeptide receptor related to Neuropeptide Y receptors2. Here we show that the NPR-1 isoform associated with solitary feeding acts in neurons exposed to the body fluid to inhibit social feeding. Furthermore, suppressing the activity of these neurons, called AQR, PQR and URX, using an activated K+ channel, inhibits social feeding. NPR-1 activity in AQR, PQR and URX neurons seems to suppress social feeding by antagonizing signalling through a cyclic GMP-gated ion channel encoded by tax-2 and tax-4. We show that mutations in tax-2 or tax-4 disrupt social feeding, and that tax-4 is required in several neurons for social feeding, including one or more of AQR, PQR and URX. The AQR, PQR and URX neurons are unusual in C. elegans because they are directly exposed to the pseudocoelomic body fluid3. Our data suggest a model in which these neurons integrate antagonistic signals to control the choice between social and solitary feeding behaviour."}],"publication_status":"published"},{"_id":"6159","doi":"10.1038/nature01169","language":[{"iso":"eng"}],"pmid":1,"publication":"Nature","title":"Social feeding in Caenorhabditis elegans is induced by neurons that detect aversive stimuli","abstract":[{"text":"Natural Caenorhabditis elegans isolates exhibit either social or solitary feeding on bacteria. We show here that social feeding is induced by nociceptive neurons that detect adverse or stressful conditions. Ablation of the nociceptive neurons ASH and ADL transforms social animals into solitary feeders. Social feeding is probably due to the sensation of noxious chemicals by ASH and ADL neurons; it requires the genes ocr-2 and osm-9, which encode TRP-related transduction channels, and odr-4 and odr-8, which are required to localize sensory chemoreceptors to cilia. Other sensory neurons may suppress social feeding, as social feeding in ocr-2 and odr-4 mutants is restored by mutations in osm-3, a gene required for the development of 26 ciliated sensory neurons. Our data suggest a model for regulation of social feeding by opposing sensory inputs: aversive inputs to nociceptive neurons promote social feeding, whereas antagonistic inputs from neurons that express osm-3 inhibit aggregation.","lang":"eng"}],"publication_status":"published","extern":"1","author":[{"first_name":"Mario","last_name":"de Bono","id":"4E3FF80E-F248-11E8-B48F-1D18A9856A87","full_name":"de Bono, Mario","orcid":"0000-0001-8347-0443"},{"full_name":"Tobin, David M.","last_name":"Tobin","first_name":"David M."},{"first_name":"M. Wayne","last_name":"Davis","full_name":"Davis, M. Wayne"},{"full_name":"Avery, Leon","first_name":"Leon","last_name":"Avery"},{"full_name":"Bargmann, Cornelia I.","first_name":"Cornelia I.","last_name":"Bargmann"}],"quality_controlled":"1","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","citation":{"ista":"de Bono M, Tobin DM, Davis MW, Avery L, Bargmann CI. 2002. Social feeding in Caenorhabditis elegans is induced by neurons that detect aversive stimuli. Nature. 419(6910), 899–903.","short":"M. de Bono, D.M. Tobin, M.W. Davis, L. Avery, C.I. Bargmann, Nature 419 (2002) 899–903.","chicago":"Bono, Mario de, David M. Tobin, M. Wayne Davis, Leon Avery, and Cornelia I. Bargmann. “Social Feeding in Caenorhabditis Elegans Is Induced by Neurons That Detect Aversive Stimuli.” <i>Nature</i>. Springer Nature, 2002. <a href=\"https://doi.org/10.1038/nature01169\">https://doi.org/10.1038/nature01169</a>.","ama":"de Bono M, Tobin DM, Davis MW, Avery L, Bargmann CI. Social feeding in Caenorhabditis elegans is induced by neurons that detect aversive stimuli. <i>Nature</i>. 2002;419(6910):899-903. doi:<a href=\"https://doi.org/10.1038/nature01169\">10.1038/nature01169</a>","ieee":"M. de Bono, D. M. Tobin, M. W. Davis, L. Avery, and C. I. Bargmann, “Social feeding in Caenorhabditis elegans is induced by neurons that detect aversive stimuli,” <i>Nature</i>, vol. 419, no. 6910. Springer Nature, pp. 899–903, 2002.","apa":"de Bono, M., Tobin, D. M., Davis, M. W., Avery, L., &#38; Bargmann, C. I. (2002). Social feeding in Caenorhabditis elegans is induced by neurons that detect aversive stimuli. <i>Nature</i>. Springer Nature. <a href=\"https://doi.org/10.1038/nature01169\">https://doi.org/10.1038/nature01169</a>","mla":"de Bono, Mario, et al. “Social Feeding in Caenorhabditis Elegans Is Induced by Neurons That Detect Aversive Stimuli.” <i>Nature</i>, vol. 419, no. 6910, Springer Nature, 2002, pp. 899–903, doi:<a href=\"https://doi.org/10.1038/nature01169\">10.1038/nature01169</a>."},"year":"2002","day":"31","oa_version":"None","date_updated":"2021-01-12T08:06:27Z","type":"journal_article","publication_identifier":{"issn":["0028-0836"]},"intvolume":"       419","status":"public","month":"10","date_created":"2019-03-21T10:27:04Z","volume":419,"issue":"6910","page":"899-903","external_id":{"pmid":["12410303"]},"date_published":"2002-10-31T00:00:00Z","publisher":"Springer Nature"},{"publisher":"Springer Nature","article_type":"original","issue":"7","volume":4,"status":"public","date_created":"2022-04-07T07:57:19Z","month":"07","intvolume":"         4","year":"2002","author":[{"first_name":"Martin W","last_name":"HETZER","id":"86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed","full_name":"HETZER, Martin W","orcid":"0000-0002-2111-992X"},{"full_name":"Gruss, Oliver J.","last_name":"Gruss","first_name":"Oliver J."},{"full_name":"Mattaj, Iain W.","last_name":"Mattaj","first_name":"Iain W."}],"extern":"1","quality_controlled":"1","citation":{"ieee":"M. Hetzer, O. J. Gruss, and I. W. Mattaj, “The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly,” <i>Nature Cell Biology</i>, vol. 4, no. 7. Springer Nature, pp. E177–E184, 2002.","ama":"Hetzer M, Gruss OJ, Mattaj IW. The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly. <i>Nature Cell Biology</i>. 2002;4(7):E177-E184. doi:<a href=\"https://doi.org/10.1038/ncb0702-e177\">10.1038/ncb0702-e177</a>","ista":"Hetzer M, Gruss OJ, Mattaj IW. 2002. The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly. Nature Cell Biology. 4(7), E177–E184.","short":"M. Hetzer, O.J. Gruss, I.W. Mattaj, Nature Cell Biology 4 (2002) E177–E184.","chicago":"Hetzer, Martin, Oliver J. Gruss, and Iain W. Mattaj. “The Ran GTPase as a Marker of Chromosome Position in Spindle Formation and Nuclear Envelope Assembly.” <i>Nature Cell Biology</i>. Springer Nature, 2002. <a href=\"https://doi.org/10.1038/ncb0702-e177\">https://doi.org/10.1038/ncb0702-e177</a>.","apa":"Hetzer, M., Gruss, O. J., &#38; Mattaj, I. W. (2002). The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly. <i>Nature Cell Biology</i>. Springer Nature. <a href=\"https://doi.org/10.1038/ncb0702-e177\">https://doi.org/10.1038/ncb0702-e177</a>","mla":"Hetzer, Martin, et al. “The Ran GTPase as a Marker of Chromosome Position in Spindle Formation and Nuclear Envelope Assembly.” <i>Nature Cell Biology</i>, vol. 4, no. 7, Springer Nature, 2002, pp. E177–84, doi:<a href=\"https://doi.org/10.1038/ncb0702-e177\">10.1038/ncb0702-e177</a>."},"publication_status":"published","abstract":[{"lang":"eng","text":"The small GTPase Ran is a key regulator of nucleocytoplasmic transport during interphase. The asymmetric distribution of the GTP-bound form of Ran across the nuclear envelope — that is, large quantities in the nucleus compared with small quantities in the cytoplasm — determines the directionality of many nuclear transport processes. Recent findings that Ran also functions in spindle formation and nuclear envelope assembly during mitosis suggest that Ran has a general role in chromatin-centred processes. Ran functions in these events as a signal for chromosome position."}],"_id":"11123","title":"The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly","publication":"Nature Cell Biology","pmid":1,"page":"E177-E184","date_published":"2002-07-01T00:00:00Z","external_id":{"pmid":["12105431"]},"keyword":["Cell Biology"],"publication_identifier":{"issn":["1465-7392"],"eissn":["1476-4679"]},"scopus_import":"1","day":"01","date_updated":"2022-07-18T08:58:03Z","type":"journal_article","oa_version":"None","article_processing_charge":"No","user_id":"72615eeb-f1f3-11ec-aa25-d4573ddc34fd","language":[{"iso":"eng"}],"doi":"10.1038/ncb0702-e177"},{"page":"1151-1156","date_published":"2002-07-09T00:00:00Z","keyword":["General Agricultural and Biological Sciences","General Biochemistry","Genetics and Molecular Biology"],"external_id":{"pmid":["12121625"]},"publication_identifier":{"issn":["0960-9822"]},"scopus_import":"1","article_processing_charge":"No","user_id":"72615eeb-f1f3-11ec-aa25-d4573ddc34fd","day":"09","date_updated":"2022-07-18T08:58:05Z","type":"journal_article","oa_version":"Published Version","language":[{"iso":"eng"}],"doi":"10.1016/s0960-9822(02)00927-2","volume":12,"issue":"13","publisher":"Elsevier BV","article_type":"letter_note","intvolume":"        12","status":"public","date_created":"2022-04-07T07:57:31Z","month":"07","quality_controlled":"1","author":[{"full_name":"Bilbao-Cortés, Daniel","last_name":"Bilbao-Cortés","first_name":"Daniel"},{"id":"86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed","orcid":"0000-0002-2111-992X","full_name":"HETZER, Martin W","last_name":"HETZER","first_name":"Martin W"},{"last_name":"Längst","first_name":"Gernot","full_name":"Längst, Gernot"},{"full_name":"Becker, Peter B.","last_name":"Becker","first_name":"Peter B."},{"full_name":"Mattaj, Iain W.","last_name":"Mattaj","first_name":"Iain W."}],"extern":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1016/S0960-9822(02)00927-2"}],"citation":{"apa":"Bilbao-Cortés, D., Hetzer, M., Längst, G., Becker, P. B., &#38; Mattaj, I. W. (2002). Ran binds to chromatin by two distinct mechanisms. <i>Current Biology</i>. Elsevier BV. <a href=\"https://doi.org/10.1016/s0960-9822(02)00927-2\">https://doi.org/10.1016/s0960-9822(02)00927-2</a>","mla":"Bilbao-Cortés, Daniel, et al. “Ran Binds to Chromatin by Two Distinct Mechanisms.” <i>Current Biology</i>, vol. 12, no. 13, Elsevier BV, 2002, pp. 1151–56, doi:<a href=\"https://doi.org/10.1016/s0960-9822(02)00927-2\">10.1016/s0960-9822(02)00927-2</a>.","ieee":"D. Bilbao-Cortés, M. Hetzer, G. Längst, P. B. Becker, and I. W. Mattaj, “Ran binds to chromatin by two distinct mechanisms,” <i>Current Biology</i>, vol. 12, no. 13. Elsevier BV, pp. 1151–1156, 2002.","ama":"Bilbao-Cortés D, Hetzer M, Längst G, Becker PB, Mattaj IW. Ran binds to chromatin by two distinct mechanisms. <i>Current Biology</i>. 2002;12(13):1151-1156. doi:<a href=\"https://doi.org/10.1016/s0960-9822(02)00927-2\">10.1016/s0960-9822(02)00927-2</a>","chicago":"Bilbao-Cortés, Daniel, Martin Hetzer, Gernot Längst, Peter B. Becker, and Iain W. Mattaj. “Ran Binds to Chromatin by Two Distinct Mechanisms.” <i>Current Biology</i>. Elsevier BV, 2002. <a href=\"https://doi.org/10.1016/s0960-9822(02)00927-2\">https://doi.org/10.1016/s0960-9822(02)00927-2</a>.","short":"D. Bilbao-Cortés, M. Hetzer, G. Längst, P.B. Becker, I.W. Mattaj, Current Biology 12 (2002) 1151–1156.","ista":"Bilbao-Cortés D, Hetzer M, Längst G, Becker PB, Mattaj IW. 2002. Ran binds to chromatin by two distinct mechanisms. Current Biology. 12(13), 1151–1156."},"year":"2002","oa":1,"_id":"11124","title":"Ran binds to chromatin by two distinct mechanisms","publication":"Current Biology","pmid":1,"publication_status":"published","abstract":[{"text":"Ran GTPase plays important roles in nucleocytoplasmic transport in interphase [1, 2] and in both spindle formation and nuclear envelope (NE) assembly during mitosis [3, 4, 5]. The latter functions rely on the presence of high local concentrations of GTP-bound Ran near mitotic chromatin [3, 4, 5]. RanGTP localization has been proposed to result from the association of Ran's GDP/GTP exchange factor, RCC1, with chromatin [6, 7, 8, 9], but Ran is shown here to bind directly to chromatin in two modes, either dependent or independent of RCC1, and, where bound, to increase the affinity of chromatin for NE membranes. We propose that the Ran binding capacity of chromatin contributes to localized spindle and NE assembly.","lang":"eng"}]},{"alternative_title":["Current Developments in Mathematics"],"publist_id":"4588","publication_identifier":{"isbn":["9781571461018"]},"month":"01","arxiv":1,"date_created":"2018-12-11T11:57:04Z","status":"public","external_id":{"arxiv":["math-ph/0204027"]},"date_published":"2002-01-01T00:00:00Z","page":"131 - 178","publisher":"International Press","title":"The ground state of the Bose gas","publication":"Current Developments in Mathematics, 2001","_id":"2338","doi":"10.48550/arXiv.math-ph/0204027","oa":1,"language":[{"iso":"eng"}],"abstract":[{"text":"Now that the low temperature properties of quantum-mechanical many-body systems (bosons) at low density, ρ, can be examined experimentally it is appropriate to revisit some of the formulas deduced by many authors 4-5 decades ago. For systems with repulsive (i.e. positive) interaction potentials the experimental low temperature state and the ground state are effectively synonymous -- and this fact is used in all modeling. In such cases, the leading term in the energy/particle is 2πℏ2aρ/m where a is the scattering length of the two-body potential. Owing to the delicate and peculiar nature of bosonic correlations (such as the strange N7/5 law for charged bosons), four decades of research failed to establish this plausible formula rigorously. The only previous lower bound for the energy was found by Dyson in 1957, but it was 14 times too small. The correct asymptotic formula has recently been obtained by us and this work will be presented. The reason behind the mathematical difficulties will be emphasized. A different formula, postulated as late as 1971 by Schick, holds in two-dimensions and this, too, will be shown to be correct. With the aid of the methodology developed to prove the lower bound for the homogeneous gas, two other problems have been successfully addressed. One is the proof by us that the Gross-Pitaevskii equation correctly describes the ground state in the `traps' actually used in the experiments. For this system it is also possible to prove complete Bose condensation, as we have shown. Another topic is a proof that Foldy's 1961 theory of a high density Bose gas of charged particles correctly describes its ground state energy.","lang":"eng"}],"publication_status":"published","main_file_link":[{"url":"http://arxiv.org/abs/math-ph/0204027","open_access":"1"}],"citation":{"mla":"Lieb, Élliott, et al. “The Ground State of the Bose Gas.” <i>Current Developments in Mathematics, 2001</i>, International Press, 2002, pp. 131–78, doi:<a href=\"https://doi.org/10.48550/arXiv.math-ph/0204027\">10.48550/arXiv.math-ph/0204027</a>.","apa":"Lieb, É., Solovej, J., Seiringer, R., &#38; Yngvason, J. (2002). The ground state of the Bose gas. In <i>Current Developments in Mathematics, 2001</i> (pp. 131–178). International Press. <a href=\"https://doi.org/10.48550/arXiv.math-ph/0204027\">https://doi.org/10.48550/arXiv.math-ph/0204027</a>","ista":"Lieb É, Solovej J, Seiringer R, Yngvason J. 2002.The ground state of the Bose gas. In: Current Developments in Mathematics, 2001. Current Developments in Mathematics, , 131–178.","chicago":"Lieb, Élliott, Jan Solovej, Robert Seiringer, and Jakob Yngvason. “The Ground State of the Bose Gas.” In <i>Current Developments in Mathematics, 2001</i>, 131–78. International Press, 2002. <a href=\"https://doi.org/10.48550/arXiv.math-ph/0204027\">https://doi.org/10.48550/arXiv.math-ph/0204027</a>.","short":"É. Lieb, J. Solovej, R. Seiringer, J. Yngvason, in:, Current Developments in Mathematics, 2001, International Press, 2002, pp. 131–178.","ieee":"É. Lieb, J. Solovej, R. Seiringer, and J. Yngvason, “The ground state of the Bose gas,” in <i>Current Developments in Mathematics, 2001</i>, International Press, 2002, pp. 131–178.","ama":"Lieb É, Solovej J, Seiringer R, Yngvason J. The ground state of the Bose gas. In: <i>Current Developments in Mathematics, 2001</i>. International Press; 2002:131-178. doi:<a href=\"https://doi.org/10.48550/arXiv.math-ph/0204027\">10.48550/arXiv.math-ph/0204027</a>"},"author":[{"full_name":"Lieb, Élliott","last_name":"Lieb","first_name":"Élliott"},{"full_name":"Solovej, Jan","first_name":"Jan","last_name":"Solovej"},{"last_name":"Seiringer","first_name":"Robert","full_name":"Seiringer, Robert","orcid":"0000-0002-6781-0521","id":"4AFD0470-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Yngvason","first_name":"Jakob","full_name":"Yngvason, Jakob"}],"article_processing_charge":"No","extern":"1","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","oa_version":"Published Version","type":"book_chapter","date_updated":"2023-07-26T08:43:46Z","year":"2002","day":"01"},{"publication_status":"published","doi":"10.1090/conm/307","_id":"2339","title":"Symmetry breaking in a model of a rotating Bose gas","day":"01","year":"2002","type":"conference","date_updated":"2021-01-12T06:56:53Z","quality_controlled":0,"author":[{"full_name":"Robert Seiringer","orcid":"0000-0002-6781-0521","id":"4AFD0470-F248-11E8-B48F-1D18A9856A87","last_name":"Seiringer","first_name":"Robert"}],"extern":1,"citation":{"ama":"Seiringer R. Symmetry breaking in a model of a rotating Bose gas. In: Weder R, Exner P, Grébert B, eds. Vol 307. World Scientific Publishing; 2002:281-286. doi:<a href=\"https://doi.org/10.1090/conm/307\">10.1090/conm/307</a>","ieee":"R. Seiringer, “Symmetry breaking in a model of a rotating Bose gas,” presented at the QMath: Mathematical Results in Quantum Physics, 2002, vol. 307, pp. 281–286.","short":"R. Seiringer, in:, R. Weder, P. Exner, B. Grébert (Eds.), World Scientific Publishing, 2002, pp. 281–286.","chicago":"Seiringer, Robert. “Symmetry Breaking in a Model of a Rotating Bose Gas.” edited by Richardo Weder, Pavel Exner, and Benoit Grébert, 307:281–86. World Scientific Publishing, 2002. <a href=\"https://doi.org/10.1090/conm/307\">https://doi.org/10.1090/conm/307</a>.","ista":"Seiringer R. 2002. Symmetry breaking in a model of a rotating Bose gas. QMath: Mathematical Results in Quantum Physics, Contemporary Mathematics, vol. 307, 281–286.","apa":"Seiringer, R. (2002). Symmetry breaking in a model of a rotating Bose gas. In R. Weder, P. Exner, &#38; B. Grébert (Eds.) (Vol. 307, pp. 281–286). Presented at the QMath: Mathematical Results in Quantum Physics, World Scientific Publishing. <a href=\"https://doi.org/10.1090/conm/307\">https://doi.org/10.1090/conm/307</a>","mla":"Seiringer, Robert. <i>Symmetry Breaking in a Model of a Rotating Bose Gas</i>. Edited by Richardo Weder et al., vol. 307, World Scientific Publishing, 2002, pp. 281–86, doi:<a href=\"https://doi.org/10.1090/conm/307\">10.1090/conm/307</a>."},"status":"public","date_created":"2018-12-11T11:57:05Z","conference":{"name":"QMath: Mathematical Results in Quantum Physics"},"month":"01","publist_id":"4587","intvolume":"       307","alternative_title":["Contemporary Mathematics"],"publisher":"World Scientific Publishing","editor":[{"first_name":"Richardo","last_name":"Weder","full_name":"Weder, Richardo"},{"last_name":"Exner","first_name":"Pavel","full_name":"Exner, Pavel"},{"full_name":"Grébert, Benoit","first_name":"Benoit","last_name":"Grébert"}],"page":"281 - 286","volume":307,"date_published":"2002-01-01T00:00:00Z"},{"publisher":"American Physical Society","date_published":"2002-04-29T00:00:00Z","page":"1704091 - 1704094","volume":88,"issue":"17","month":"04","date_created":"2018-12-11T11:57:08Z","status":"public","intvolume":"        88","publist_id":"4577","date_updated":"2021-01-12T06:56:56Z","type":"journal_article","year":"2002","day":"29","citation":{"mla":"Lieb, Élliott, and Robert Seiringer. “Proof of Bose-Einstein Condensation for Dilute Trapped Gases.” <i>Physical Review Letters</i>, vol. 88, no. 17, American Physical Society, 2002, pp. 1704091–94, doi:<a href=\"https://doi.org/10.1103/PhysRevLett.88.170409\">10.1103/PhysRevLett.88.170409</a>.","apa":"Lieb, É., &#38; Seiringer, R. (2002). Proof of Bose-Einstein condensation for dilute trapped gases. <i>Physical Review Letters</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevLett.88.170409\">https://doi.org/10.1103/PhysRevLett.88.170409</a>","ieee":"É. Lieb and R. Seiringer, “Proof of Bose-Einstein condensation for dilute trapped gases,” <i>Physical Review Letters</i>, vol. 88, no. 17. American Physical Society, pp. 1704091–1704094, 2002.","ama":"Lieb É, Seiringer R. Proof of Bose-Einstein condensation for dilute trapped gases. <i>Physical Review Letters</i>. 2002;88(17):1704091-1704094. doi:<a href=\"https://doi.org/10.1103/PhysRevLett.88.170409\">10.1103/PhysRevLett.88.170409</a>","short":"É. Lieb, R. Seiringer, Physical Review Letters 88 (2002) 1704091–1704094.","chicago":"Lieb, Élliott, and Robert Seiringer. “Proof of Bose-Einstein Condensation for Dilute Trapped Gases.” <i>Physical Review Letters</i>. American Physical Society, 2002. <a href=\"https://doi.org/10.1103/PhysRevLett.88.170409\">https://doi.org/10.1103/PhysRevLett.88.170409</a>.","ista":"Lieb É, Seiringer R. 2002. Proof of Bose-Einstein condensation for dilute trapped gases. Physical Review Letters. 88(17), 1704091–1704094."},"main_file_link":[{"open_access":"1","url":"http://arxiv.org/abs/math-ph/0112032"}],"extern":1,"author":[{"full_name":"Lieb, Élliott H","first_name":"Élliott","last_name":"Lieb"},{"full_name":"Robert Seiringer","orcid":"0000-0002-6781-0521","id":"4AFD0470-F248-11E8-B48F-1D18A9856A87","last_name":"Seiringer","first_name":"Robert"}],"quality_controlled":0,"abstract":[{"text":"The Bose-Einstein condensation (BEC) of the ground state of bosonic atoms in a trap was discussed. The BEC was proved for bosons with two-body repulsive interaction potentials in the dilute limit, starting from the basic Schrodinger equation. The BEC was 100% into the state which minimized the Gross-Pitaevskii energy functional. The analysis also included rigorous proof of BEC in a physically realistic, continuum model.","lang":"eng"}],"publication_status":"published","title":"Proof of Bose-Einstein condensation for dilute trapped gases","publication":"Physical Review Letters","_id":"2349","oa":1,"doi":"10.1103/PhysRevLett.88.170409"},{"publist_id":"4574","intvolume":"         6","status":"public","date_created":"2018-12-11T11:57:09Z","month":"09","volume":6,"issue":"5","publisher":"International Press","article_type":"original","oa":1,"_id":"2350","publication":"Advances in Theoretical and Mathematical Physics","title":"Mass renormalization and energy level shift in non-relativistic QED","publication_status":"published","abstract":[{"lang":"eng","text":"Using the Pauli-Fierz model of non-relativistic quantum electrodynamics, we calculate the binding energy of an electron in the field of a nucleus of charge Z and in presence of the quantized radiation field. We consider the case of small coupling constant α, but fixed Zα and ultraviolet cut-off Λ. We prove that after renormalizing the mass the binding energy has, to leading order in α, a finite limit as Λ goes to infinity; i.e., the cut-off can be removed. The expression for the ground state energy shift thus obtained agrees with Bethe's formula for small values of Zα, but shows a different behavior for bigger values."}],"author":[{"full_name":"Hainzl, Christian","first_name":"Christian","last_name":"Hainzl"},{"id":"4AFD0470-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6781-0521","full_name":"Seiringer, Robert","first_name":"Robert","last_name":"Seiringer"}],"quality_controlled":"1","extern":"1","citation":{"ista":"Hainzl C, Seiringer R. 2002. Mass renormalization and energy level shift in non-relativistic QED. Advances in Theoretical and Mathematical Physics. 6(5), 847–871.","short":"C. Hainzl, R. Seiringer, Advances in Theoretical and Mathematical Physics 6 (2002) 847–871.","chicago":"Hainzl, Christian, and Robert Seiringer. “Mass Renormalization and Energy Level Shift in Non-Relativistic QED.” <i>Advances in Theoretical and Mathematical Physics</i>. International Press, 2002. <a href=\"https://doi.org/10.4310/ATMP.2002.v6.n5.a3\">https://doi.org/10.4310/ATMP.2002.v6.n5.a3</a>.","ama":"Hainzl C, Seiringer R. Mass renormalization and energy level shift in non-relativistic QED. <i>Advances in Theoretical and Mathematical Physics</i>. 2002;6(5):847-871. doi:<a href=\"https://doi.org/10.4310/ATMP.2002.v6.n5.a3\">10.4310/ATMP.2002.v6.n5.a3</a>","ieee":"C. Hainzl and R. Seiringer, “Mass renormalization and energy level shift in non-relativistic QED,” <i>Advances in Theoretical and Mathematical Physics</i>, vol. 6, no. 5. International Press, pp. 847–871, 2002.","apa":"Hainzl, C., &#38; Seiringer, R. (2002). Mass renormalization and energy level shift in non-relativistic QED. <i>Advances in Theoretical and Mathematical Physics</i>. International Press. <a href=\"https://doi.org/10.4310/ATMP.2002.v6.n5.a3\">https://doi.org/10.4310/ATMP.2002.v6.n5.a3</a>","mla":"Hainzl, Christian, and Robert Seiringer. “Mass Renormalization and Energy Level Shift in Non-Relativistic QED.” <i>Advances in Theoretical and Mathematical Physics</i>, vol. 6, no. 5, International Press, 2002, pp. 847–71, doi:<a href=\"https://doi.org/10.4310/ATMP.2002.v6.n5.a3\">10.4310/ATMP.2002.v6.n5.a3</a>."},"main_file_link":[{"open_access":"1","url":"http://arxiv.org/abs/math-ph/0205044"}],"year":"2002","publication_identifier":{"issn":["1095-0761"]},"scopus_import":"1","arxiv":1,"page":"847 - 871","date_published":"2002-09-01T00:00:00Z","external_id":{"arxiv":["math-ph/0205044v3"]},"doi":"10.4310/ATMP.2002.v6.n5.a3","language":[{"iso":"eng"}],"acknowledgement":"We are grateful to Elliott Lieb for helpful discussions. C.H. was supported by a Marie Curie Fellowship of the European Community programme “Improving Human Research Potential and the Socioeconomic Knowledge Base” under contract number HPMFCT-2000-00660 and by the Deutsche Forschungsgemeinschaft, and acknowledges kind hospitality at Princeton University, where part of this work was done. R.S. was supported by the Austrian Science Fund in the form of an Erwin Schrödinger Fellowship.\r\n","article_processing_charge":"No","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","day":"01","type":"journal_article","date_updated":"2023-07-26T08:29:28Z","oa_version":"Published Version"},{"publisher":"Springer","date_published":"2002-09-01T00:00:00Z","page":"491 - 509","volume":229,"issue":"3","date_created":"2018-12-11T11:57:09Z","month":"09","status":"public","intvolume":"       229","publist_id":"4575","type":"journal_article","date_updated":"2021-01-12T06:56:57Z","day":"01","year":"2002","citation":{"apa":"Seiringer, R. (2002). Gross-Pitaevskii theory of the rotating Bose gas. <i>Communications in Mathematical Physics</i>. Springer. <a href=\"https://doi.org/10.1007/s00220-002-0695-2\">https://doi.org/10.1007/s00220-002-0695-2</a>","mla":"Seiringer, Robert. “Gross-Pitaevskii Theory of the Rotating Bose Gas.” <i>Communications in Mathematical Physics</i>, vol. 229, no. 3, Springer, 2002, pp. 491–509, doi:<a href=\"https://doi.org/10.1007/s00220-002-0695-2\">10.1007/s00220-002-0695-2</a>.","ieee":"R. Seiringer, “Gross-Pitaevskii theory of the rotating Bose gas,” <i>Communications in Mathematical Physics</i>, vol. 229, no. 3. Springer, pp. 491–509, 2002.","ama":"Seiringer R. Gross-Pitaevskii theory of the rotating Bose gas. <i>Communications in Mathematical Physics</i>. 2002;229(3):491-509. doi:<a href=\"https://doi.org/10.1007/s00220-002-0695-2\">10.1007/s00220-002-0695-2</a>","chicago":"Seiringer, Robert. “Gross-Pitaevskii Theory of the Rotating Bose Gas.” <i>Communications in Mathematical Physics</i>. Springer, 2002. <a href=\"https://doi.org/10.1007/s00220-002-0695-2\">https://doi.org/10.1007/s00220-002-0695-2</a>.","short":"R. Seiringer, Communications in Mathematical Physics 229 (2002) 491–509.","ista":"Seiringer R. 2002. Gross-Pitaevskii theory of the rotating Bose gas. Communications in Mathematical Physics. 229(3), 491–509."},"main_file_link":[{"open_access":"1","url":"http://arxiv.org/abs/math-ph/0110010"}],"extern":1,"quality_controlled":0,"author":[{"last_name":"Seiringer","first_name":"Robert","orcid":"0000-0002-6781-0521","full_name":"Robert Seiringer","id":"4AFD0470-F248-11E8-B48F-1D18A9856A87"}],"publication_status":"published","abstract":[{"lang":"eng","text":"We study the Gross-Pitaevskii functional for a rotating two-dimensional Bose gas in a trap. We prove that there is a breaking of the rotational symmetry in the ground state; more precisely, for any value of the angular velocity and for large enough values of the interaction strength, the ground state of the functional is not an eigenfunction of the angular momentum. This has interesting consequences on the Bose gas with spin; in particular, the ground state energy depends non-trivially on the number of spin components, and the different components do not have the same wave function. For the special case of a harmonic trap potential, we give explicit upper and lower bounds on the critical coupling constant for symmetry breaking."}],"publication":"Communications in Mathematical Physics","title":"Gross-Pitaevskii theory of the rotating Bose gas","oa":1,"doi":"10.1007/s00220-002-0695-2","_id":"2351"},{"page":"75 - 84","volume":61,"issue":"1","date_published":"2002-07-01T00:00:00Z","publisher":"Springer","publist_id":"4576","intvolume":"        61","status":"public","date_created":"2018-12-11T11:57:09Z","month":"07","author":[{"full_name":"Hainzl, Christian","last_name":"Hainzl","first_name":"Christian"},{"id":"4AFD0470-F248-11E8-B48F-1D18A9856A87","full_name":"Robert Seiringer","orcid":"0000-0002-6781-0521","last_name":"Seiringer","first_name":"Robert"}],"quality_controlled":0,"extern":1,"citation":{"mla":"Hainzl, Christian, and Robert Seiringer. “General Decomposition of Radial Functions on ℝn and Applications to N-Body Quantum Systems.” <i>Letters in Mathematical Physics</i>, vol. 61, no. 1, Springer, 2002, pp. 75–84, doi:<a href=\"https://doi.org/10.1023/A:1020204818938\">10.1023/A:1020204818938</a>.","apa":"Hainzl, C., &#38; Seiringer, R. (2002). General decomposition of radial functions on ℝn and applications to N-body quantum systems. <i>Letters in Mathematical Physics</i>. Springer. <a href=\"https://doi.org/10.1023/A:1020204818938\">https://doi.org/10.1023/A:1020204818938</a>","short":"C. Hainzl, R. Seiringer, Letters in Mathematical Physics 61 (2002) 75–84.","chicago":"Hainzl, Christian, and Robert Seiringer. “General Decomposition of Radial Functions on ℝn and Applications to N-Body Quantum Systems.” <i>Letters in Mathematical Physics</i>. Springer, 2002. <a href=\"https://doi.org/10.1023/A:1020204818938\">https://doi.org/10.1023/A:1020204818938</a>.","ista":"Hainzl C, Seiringer R. 2002. General decomposition of radial functions on ℝn and applications to N-body quantum systems. Letters in Mathematical Physics. 61(1), 75–84.","ieee":"C. Hainzl and R. Seiringer, “General decomposition of radial functions on ℝn and applications to N-body quantum systems,” <i>Letters in Mathematical Physics</i>, vol. 61, no. 1. Springer, pp. 75–84, 2002.","ama":"Hainzl C, Seiringer R. General decomposition of radial functions on ℝn and applications to N-body quantum systems. <i>Letters in Mathematical Physics</i>. 2002;61(1):75-84. doi:<a href=\"https://doi.org/10.1023/A:1020204818938\">10.1023/A:1020204818938</a>"},"main_file_link":[{"url":"http://arxiv.org/abs/math-ph/0107011","open_access":"1"}],"day":"01","year":"2002","type":"journal_article","date_updated":"2021-01-12T06:56:58Z","doi":"10.1023/A:1020204818938","oa":1,"_id":"2352","publication":"Letters in Mathematical Physics","title":"General decomposition of radial functions on ℝn and applications to N-body quantum systems","publication_status":"published","abstract":[{"text":"We present a generalization of the Fefferman-de la Llave decomposition of the Coulomb potential to quite arbitrary radial functions V on ℝn going to zero at infinity. This generalized decomposition can be used to extend previous results on N-body quantum systems with Coulomb interaction to a more general class of interactions. As an example of such an application, we derive the high density asymptotics of the ground state energy of jellium with Yukawa interaction in the thermodynamic limit, using a correlation estimate by Graf and Solovej.","lang":"eng"}]},{"scopus_import":"1","publication_identifier":{"issn":["0163-1829"]},"arxiv":1,"external_id":{"arxiv":["cond-mat/0205570"]},"date_published":"2002-10-01T00:00:00Z","language":[{"iso":"eng"}],"doi":"10.1103/PhysRevB.66.134529","acknowledgement":"E.H.L. was partially supported by the U.S. National Science Foundation, Grant No. PHY 98-20650. R.S. was supported by the Austrian Science Fund in the from of an Erwin Schrödinger fellowship.","article_processing_charge":"No","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","day":"01","oa_version":"None","date_updated":"2023-07-25T12:05:47Z","type":"journal_article","publist_id":"4573","intvolume":"        66","status":"public","month":"10","date_created":"2018-12-11T11:57:10Z","issue":"13","volume":66,"publisher":"American Physical Society","article_type":"original","_id":"2353","oa":1,"title":"Superfluidity in dilute trapped Bose gases","publication":"Physical Review B - Condensed Matter and Materials Physics","abstract":[{"lang":"eng","text":"A commonly used theoretical definition of superfluidity in the ground state of a Bose gas is based on the response of the system to an imposed velocity field or, equivalently, to twisted boundary conditions in a box. We are able to carry out this program in the case of a dilute interacting Bose gas in a trap, and we prove that a gas with repulsive interactions is 100% superfluid in the dilute limit in which the Gross-Pitaevskii equation is exact. This is the first example in an experimentally realistic continuum model in which superfluidity is rigorously verified."}],"publication_status":"published","quality_controlled":"1","extern":"1","author":[{"full_name":"Lieb, Élliott","last_name":"Lieb","first_name":"Élliott"},{"last_name":"Seiringer","first_name":"Robert","id":"4AFD0470-F248-11E8-B48F-1D18A9856A87","full_name":"Seiringer, Robert","orcid":"0000-0002-6781-0521"},{"full_name":"Yngvason, Jakob","first_name":"Jakob","last_name":"Yngvason"}],"citation":{"mla":"Lieb, Élliott, et al. “Superfluidity in Dilute Trapped Bose Gases.” <i>Physical Review B - Condensed Matter and Materials Physics</i>, vol. 66, no. 13, American Physical Society, 2002, doi:<a href=\"https://doi.org/10.1103/PhysRevB.66.134529\">10.1103/PhysRevB.66.134529</a>.","apa":"Lieb, É., Seiringer, R., &#38; Yngvason, J. (2002). Superfluidity in dilute trapped Bose gases. <i>Physical Review B - Condensed Matter and Materials Physics</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevB.66.134529\">https://doi.org/10.1103/PhysRevB.66.134529</a>","ama":"Lieb É, Seiringer R, Yngvason J. Superfluidity in dilute trapped Bose gases. <i>Physical Review B - Condensed Matter and Materials Physics</i>. 2002;66(13). doi:<a href=\"https://doi.org/10.1103/PhysRevB.66.134529\">10.1103/PhysRevB.66.134529</a>","ieee":"É. Lieb, R. Seiringer, and J. Yngvason, “Superfluidity in dilute trapped Bose gases,” <i>Physical Review B - Condensed Matter and Materials Physics</i>, vol. 66, no. 13. American Physical Society, 2002.","ista":"Lieb É, Seiringer R, Yngvason J. 2002. Superfluidity in dilute trapped Bose gases. Physical Review B - Condensed Matter and Materials Physics. 66(13).","chicago":"Lieb, Élliott, Robert Seiringer, and Jakob Yngvason. “Superfluidity in Dilute Trapped Bose Gases.” <i>Physical Review B - Condensed Matter and Materials Physics</i>. American Physical Society, 2002. <a href=\"https://doi.org/10.1103/PhysRevB.66.134529\">https://doi.org/10.1103/PhysRevB.66.134529</a>.","short":"É. Lieb, R. Seiringer, J. Yngvason, Physical Review B - Condensed Matter and Materials Physics 66 (2002)."},"main_file_link":[{"url":"http://arxiv.org/abs/cond-mat/0205570","open_access":"1"}],"year":"2002"},{"page":"152 - 161","date_published":"2002-08-01T00:00:00Z","publication_identifier":{"issn":["0196-8858"]},"scopus_import":"1","day":"01","date_updated":"2023-07-25T11:55:42Z","type":"journal_article","oa_version":"None","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","article_processing_charge":"No","acknowledgement":"I first learned about corner cuts in a seminar talk in which Artur Andrzejak\r\npresented the results from [6]. My work was initiated by that presentation and\r\nby the discussions that followed it. I also thank Komei Fukuda, Ingo Schurr, and\r\nEmo Welzl for helpful comments and discussions.","doi":"10.1016/S0196-8858(02)00014-3","language":[{"iso":"eng"}],"article_type":"original","publisher":"ACM","volume":29,"issue":"2","status":"public","date_created":"2018-12-11T11:57:33Z","month":"08","publist_id":"4505","intvolume":"        29","year":"2002","quality_controlled":"1","extern":"1","author":[{"last_name":"Wagner","first_name":"Uli","id":"36690CA2-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-1494-0568","full_name":"Wagner, Uli"}],"citation":{"short":"U. Wagner, Advances in Applied Mathematics 29 (2002) 152–161.","chicago":"Wagner, Uli. “On the Number of Corner Cuts.” <i>Advances in Applied Mathematics</i>. ACM, 2002. <a href=\"https://doi.org/10.1016/S0196-8858(02)00014-3\">https://doi.org/10.1016/S0196-8858(02)00014-3</a>.","ista":"Wagner U. 2002. On the number of corner cuts. Advances in Applied Mathematics. 29(2), 152–161.","ieee":"U. Wagner, “On the number of corner cuts,” <i>Advances in Applied Mathematics</i>, vol. 29, no. 2. ACM, pp. 152–161, 2002.","ama":"Wagner U. On the number of corner cuts. <i>Advances in Applied Mathematics</i>. 2002;29(2):152-161. doi:<a href=\"https://doi.org/10.1016/S0196-8858(02)00014-3\">10.1016/S0196-8858(02)00014-3</a>","mla":"Wagner, Uli. “On the Number of Corner Cuts.” <i>Advances in Applied Mathematics</i>, vol. 29, no. 2, ACM, 2002, pp. 152–61, doi:<a href=\"https://doi.org/10.1016/S0196-8858(02)00014-3\">10.1016/S0196-8858(02)00014-3</a>.","apa":"Wagner, U. (2002). On the number of corner cuts. <i>Advances in Applied Mathematics</i>. ACM. <a href=\"https://doi.org/10.1016/S0196-8858(02)00014-3\">https://doi.org/10.1016/S0196-8858(02)00014-3</a>"},"publication_status":"published","abstract":[{"text":"A corner cut in dimension d is a finite subset of N0d that can be separated from its complement in N0d by an affine hyperplane disjoint from N0d. Corner cuts were first investigated by Onn and Sturmfels [Adv. Appl. Math. 23 (1999) 29-48], their original motivation stemmed from computational commutative algebra. Let us write (Nd0k)cut for the set of corner cuts of cardinality k; in the computational geometer's terminology, these are the k-sets of N0d. Among other things, Onn and Sturmfels give an upper bound of O(k2d(d-1)/(d+1)) for the size of (Nd0k)cut when the dimension is fixed. In two dimensions, it is known (see [Corteel et al., Adv. Appl. Math. 23 (1) (1999) 49-53]) that #(Nd0k)cut = Θ(k log k). We will see that in general, for any fixed dimension d, the order of magnitude of #(Nd0k)cut is between kd-1 log k and (k log k)d-1. (It has been communicated to me that the same bounds have been found independently by G. Rémond.) In fact, the elements of (Nd0k)cut correspond to the vertices of a certain polytope, and what our proof shows is that the above upper bound holds for the total number of flags of that polytope.","lang":"eng"}],"_id":"2420","title":"On the number of corner cuts","publication":"Advances in Applied Mathematics"},{"volume":2518,"publisher":"Springer","intvolume":"      2518","publist_id":"4504","month":"01","conference":{"location":"Vancouver, Canada","start_date":"2002-11-21","end_date":"2002-11-23","name":"ISAAC: International Symposium on Algorithms and Computation"},"date_created":"2018-12-11T11:57:34Z","status":"public","citation":{"apa":"Ambühl, C., &#38; Wagner, U. (2002). On the Clique problem in intersection graphs of ellipses. In <i>Proceedings of the 13th International Symposium on Algorithms and Computation</i> (Vol. 2518, pp. 489–500). Vancouver, Canada: Springer. <a href=\"https://doi.org/10.1007/3-540-36136-7_43\">https://doi.org/10.1007/3-540-36136-7_43</a>","mla":"Ambühl, Christoph, and Uli Wagner. “On the Clique Problem in Intersection Graphs of Ellipses.” <i>Proceedings of the 13th International Symposium on Algorithms and Computation</i>, vol. 2518, Springer, 2002, pp. 489–500, doi:<a href=\"https://doi.org/10.1007/3-540-36136-7_43\">10.1007/3-540-36136-7_43</a>.","ista":"Ambühl C, Wagner U. 2002. On the Clique problem in intersection graphs of ellipses. Proceedings of the 13th International Symposium on Algorithms and Computation. ISAAC: International Symposium on Algorithms and Computation, LNCS, vol. 2518, 489–500.","short":"C. Ambühl, U. Wagner, in:, Proceedings of the 13th International Symposium on Algorithms and Computation, Springer, 2002, pp. 489–500.","chicago":"Ambühl, Christoph, and Uli Wagner. “On the Clique Problem in Intersection Graphs of Ellipses.” In <i>Proceedings of the 13th International Symposium on Algorithms and Computation</i>, 2518:489–500. Springer, 2002. <a href=\"https://doi.org/10.1007/3-540-36136-7_43\">https://doi.org/10.1007/3-540-36136-7_43</a>.","ieee":"C. Ambühl and U. Wagner, “On the Clique problem in intersection graphs of ellipses,” in <i>Proceedings of the 13th International Symposium on Algorithms and Computation</i>, Vancouver, Canada, 2002, vol. 2518, pp. 489–500.","ama":"Ambühl C, Wagner U. On the Clique problem in intersection graphs of ellipses. In: <i>Proceedings of the 13th International Symposium on Algorithms and Computation</i>. Vol 2518. Springer; 2002:489-500. doi:<a href=\"https://doi.org/10.1007/3-540-36136-7_43\">10.1007/3-540-36136-7_43</a>"},"author":[{"first_name":"Christoph","last_name":"Ambühl","full_name":"Ambühl, Christoph"},{"last_name":"Wagner","first_name":"Uli","orcid":"0000-0002-1494-0568","full_name":"Wagner, Uli","id":"36690CA2-F248-11E8-B48F-1D18A9856A87"}],"extern":"1","quality_controlled":"1","year":"2002","title":"On the Clique problem in intersection graphs of ellipses","publication":"Proceedings of the 13th International Symposium on Algorithms and Computation","_id":"2421","abstract":[{"lang":"eng","text":"Intersection graphs of disks and of line segments, respectively, have been well studied, because of both, practical applications and theoretically interesting properties of these graphs. Despite partial results, the complexity status of the Clique problem for these two graph classes is still open. Here, we consider the Clique problem for intersection graphs of ellipses which in a sense, interpolate between disc and ellipses, and show that it is APX-hard in that case. Moreover, this holds even if for all ellipses, the ratio of the larger over the smaller radius is some prescribed number. To our knowledge, this is the first hardness result for the Clique problem in intersection graphs of objects with finite description complexity. We also describe a simple approximation algorithm for the case of ellipses for which the ratio of radii is bounded."}],"publication_status":"published","date_published":"2002-01-01T00:00:00Z","page":"489 - 500","alternative_title":["LNCS"],"scopus_import":"1","publication_identifier":{"isbn":["9783540001423"]},"user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","article_processing_charge":"No","oa_version":"None","date_updated":"2023-07-25T11:48:36Z","type":"conference","day":"01","language":[{"iso":"eng"}],"doi":"10.1007/3-540-36136-7_43"},{"day":"15","oa_version":"None","date_updated":"2023-07-25T11:34:46Z","type":"journal_article","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","article_processing_charge":"No","acknowledgement":"This work was supported in part by research grants from the Ministry of Education, Science and Culture of Japan. We thank Bert Vogelstein for providing adenoviral recombination vectors and Haruhiko Bito for a gift of the enolase promoter and technical advice. We are grateful to Atsushi Nishimune and Satoshi Kaneko for technical advice and Kumlesh K. Dev for careful reading of this manuscript.","doi":"10.1523/JNEUROSCI.22-04-01280.2002","language":[{"iso":"eng"}],"page":"1280 - 1289","external_id":{"pmid":["11850456"]},"date_published":"2002-02-15T00:00:00Z","scopus_import":"1","publication_identifier":{"issn":["0270-6474"]},"year":"2002","quality_controlled":"1","author":[{"full_name":"Kitano, Jun","last_name":"Kitano","first_name":"Jun"},{"full_name":"Kimura, Kouji","first_name":"Kouji","last_name":"Kimura"},{"full_name":"Yamazaki, Yoshimitsu","last_name":"Yamazaki","first_name":"Yoshimitsu"},{"first_name":"Takeshi","last_name":"Soda","full_name":"Soda, Takeshi"},{"id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","full_name":"Shigemoto, Ryuichi","orcid":"0000-0001-8761-9444","last_name":"Shigemoto","first_name":"Ryuichi"},{"full_name":"Nakajima, Yoshiaki","first_name":"Yoshiaki","last_name":"Nakajima"},{"full_name":"Nakanishi, Shigetada","first_name":"Shigetada","last_name":"Nakanishi"}],"extern":"1","citation":{"short":"J. Kitano, K. Kimura, Y. Yamazaki, T. Soda, R. Shigemoto, Y. Nakajima, S. Nakanishi, Journal of Neuroscience 22 (2002) 1280–1289.","chicago":"Kitano, Jun, Kouji Kimura, Yoshimitsu Yamazaki, Takeshi Soda, Ryuichi Shigemoto, Yoshiaki Nakajima, and Shigetada Nakanishi. “Tamalin, a PDZ Domain-Containing Protein, Links a Protein Complex Formation of Group 1 Metabotropic Glutamate Receptors and the Guanine Nucleotide Exchange Factor Cytohesins.” <i>Journal of Neuroscience</i>. Society for Neuroscience, 2002. <a href=\"https://doi.org/10.1523/JNEUROSCI.22-04-01280.2002\">https://doi.org/10.1523/JNEUROSCI.22-04-01280.2002</a>.","ista":"Kitano J, Kimura K, Yamazaki Y, Soda T, Shigemoto R, Nakajima Y, Nakanishi S. 2002. Tamalin, a PDZ domain-containing protein, links a protein complex formation of group 1 metabotropic glutamate receptors and the guanine nucleotide exchange factor cytohesins. Journal of Neuroscience. 22(4), 1280–1289.","ieee":"J. Kitano <i>et al.</i>, “Tamalin, a PDZ domain-containing protein, links a protein complex formation of group 1 metabotropic glutamate receptors and the guanine nucleotide exchange factor cytohesins,” <i>Journal of Neuroscience</i>, vol. 22, no. 4. Society for Neuroscience, pp. 1280–1289, 2002.","ama":"Kitano J, Kimura K, Yamazaki Y, et al. Tamalin, a PDZ domain-containing protein, links a protein complex formation of group 1 metabotropic glutamate receptors and the guanine nucleotide exchange factor cytohesins. <i>Journal of Neuroscience</i>. 2002;22(4):1280-1289. doi:<a href=\"https://doi.org/10.1523/JNEUROSCI.22-04-01280.2002\">10.1523/JNEUROSCI.22-04-01280.2002</a>","apa":"Kitano, J., Kimura, K., Yamazaki, Y., Soda, T., Shigemoto, R., Nakajima, Y., &#38; Nakanishi, S. (2002). Tamalin, a PDZ domain-containing protein, links a protein complex formation of group 1 metabotropic glutamate receptors and the guanine nucleotide exchange factor cytohesins. <i>Journal of Neuroscience</i>. Society for Neuroscience. <a href=\"https://doi.org/10.1523/JNEUROSCI.22-04-01280.2002\">https://doi.org/10.1523/JNEUROSCI.22-04-01280.2002</a>","mla":"Kitano, Jun, et al. “Tamalin, a PDZ Domain-Containing Protein, Links a Protein Complex Formation of Group 1 Metabotropic Glutamate Receptors and the Guanine Nucleotide Exchange Factor Cytohesins.” <i>Journal of Neuroscience</i>, vol. 22, no. 4, Society for Neuroscience, 2002, pp. 1280–89, doi:<a href=\"https://doi.org/10.1523/JNEUROSCI.22-04-01280.2002\">10.1523/JNEUROSCI.22-04-01280.2002</a>."},"abstract":[{"text":"In this investigation, we report identification and characterization of a 95 kDa postsynaptic density protein (PSD-95)/discs-large/ ZO-1 (PDZ) domain-containing protein termed tamalin, also recently named GRP1-associated scaffold protein (GRASP), that interacts with group 1 metabotropic glutamate receptors (mGluRs). The yeast two-hybrid system and in vitro pull-down assays indicated that the PDZ domain-containing, amino-terminal half of tamalin directly binds to the class I PDZ-binding motif of group 1 mGluRs. The C-terminal half of tamalin also bound to cytohesins, the members of guanine nucleotide exchange factors (GEFs) specific for the ADP-ribosylation factor (ARF) family of small GTP-binding proteins. Tamalin mRNA is expressed predominantly in the telencephalic region and highly overlaps with the expression of group 1 mGluR mRNAs. Both tamalin and cytohesin-2 were enriched and codistributed with mGluR1a in postsynaptic membrane fractions. Importantly, recombinant and native mGluR1a/tamalin/cytohesin-2 complexes were coimmunoprecipitated from transfected COS-7 cells and rat brain tissue, respectively. Transfection of tamalin and mutant tamalin lacking a cytohesin-binding domain caused an increase and decrease in cell-surface expression of mGluR1a in COS-7 cells, respectively. Furthermore, adenovirus-mediated expression of tamalin and dominant-negative tamalin facilitated and reduced the neuritic distribution of endogenous mGluR5 in cultured hippocampal neurons, respectively. The results indicate that tamalin plays a key role in the association of group 1 mGluRs with the ARF-specific GEF proteins and contributes to intracellular trafficking and the macromolecular organization of group 1 mGluRs at synapses.","lang":"eng"}],"publication_status":"published","_id":"2613","pmid":1,"title":"Tamalin, a PDZ domain-containing protein, links a protein complex formation of group 1 metabotropic glutamate receptors and the guanine nucleotide exchange factor cytohesins","publication":"Journal of Neuroscience","article_type":"original","publisher":"Society for Neuroscience","volume":22,"issue":"4","status":"public","month":"02","date_created":"2018-12-11T11:58:40Z","publist_id":"4285","intvolume":"        22"},{"doi":"10.1074/jbc.M109044200","language":[{"iso":"eng"}],"has_accepted_license":"1","acknowledgement":"We thank Dr. Enrique Castro from Las Palmas University for critical reading of the manuscript and M. Sefton for editorial assistance.","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","article_processing_charge":"No","type":"journal_article","date_updated":"2023-07-25T10:16:44Z","oa_version":"Published Version","day":"19","publication_identifier":{"issn":["0021-9258"]},"scopus_import":"1","date_published":"2002-04-19T00:00:00Z","file":[{"file_size":2105520,"creator":"alisjak","content_type":"application/pdf","relation":"main_file","date_created":"2023-07-25T10:13:16Z","checksum":"0290fcbbd9153ec654185b0c856f214c","file_name":"2002_JBC_Millan.pdf","access_level":"open_access","success":1,"date_updated":"2023-07-25T10:13:16Z","file_id":"13309"}],"external_id":{"pmid":["11825890"]},"page":"14092 - 14101","title":"The inhibition of glutamate release by metabotropic glutamate receptor 7 affects both [Ca2+]c and cAMP. Evidence for a strong reduction of Ca2+ entry in single nerve terminals","publication":"Journal of Biological Chemistry","pmid":1,"ddc":["570"],"oa":1,"_id":"2614","publication_status":"published","abstract":[{"text":"Metabotropic glutamate receptors (mGluRs) from group III reduce glutamate release. Because these receptors reduce cAMP levels, we explored whether this signaling pathway contributes to release inhibition caused by mGluRs with low affinity for L-2-amino-4-phosphonobutyrate (L-AP4). In biochemical experiments with the population of cerebrocortical nerve terminals we find that L-AP4 (1 mM) inhibited the Ca2+dependent-evoked release of glutamate by 25%. This inhibitory effect was largely prevented by the pertussis toxin but was insensitive to inhibitors of protein kinase C bisindolylmaleimide and protein kinase A H-89. Furthermore, this inhibition was associated with reduction in N-type Ca2+ channel activity in the absence of any detectable change in cAMP levels. In the presence of forskolin, however, L-AP4 decreased the levels of cAMP. The activation of this additional signaling pathway was very efficient in counteracting the facilitation of glutamate release induced either by forskolin or the β-adrenergic receptor agonist isoproterenol. Imaging experiments to measure Ca2+ dynamics in single nerve terminals showed that L-AP4 strongly reduced the Ca2+ response in 28% of the nerve terminals. Moreover, immunochemical experiments showed that 25-35% of the nerve terminals that were immunopositive to synaptophysin were also immunoreactive to the low affinity L-AP4-sensitive mGluR7. Then, mGluR7 mediates the inhibition of glutamate release caused by 1 mM L-AP4, primarily by a strong inhibition of Ca2+ channels, although high cAMP uncovers the receptor ability to decrease cAMP.","lang":"eng"}],"citation":{"ama":"Millán C, Luján R, Shigemoto R, Sánchez Prieto J. The inhibition of glutamate release by metabotropic glutamate receptor 7 affects both [Ca2+]c and cAMP. Evidence for a strong reduction of Ca2+ entry in single nerve terminals. <i>Journal of Biological Chemistry</i>. 2002;277(16):14092-14101. doi:<a href=\"https://doi.org/10.1074/jbc.M109044200\">10.1074/jbc.M109044200</a>","ieee":"C. Millán, R. Luján, R. Shigemoto, and J. Sánchez Prieto, “The inhibition of glutamate release by metabotropic glutamate receptor 7 affects both [Ca2+]c and cAMP. Evidence for a strong reduction of Ca2+ entry in single nerve terminals,” <i>Journal of Biological Chemistry</i>, vol. 277, no. 16. American Society for Biochemistry and Molecular Biology, pp. 14092–14101, 2002.","short":"C. Millán, R. Luján, R. Shigemoto, J. Sánchez Prieto, Journal of Biological Chemistry 277 (2002) 14092–14101.","chicago":"Millán, Carmelo, Rafael Luján, Ryuichi Shigemoto, and José Sánchez Prieto. “The Inhibition of Glutamate Release by Metabotropic Glutamate Receptor 7 Affects Both [Ca2+]c and CAMP. Evidence for a Strong Reduction of Ca2+ Entry in Single Nerve Terminals.” <i>Journal of Biological Chemistry</i>. American Society for Biochemistry and Molecular Biology, 2002. <a href=\"https://doi.org/10.1074/jbc.M109044200\">https://doi.org/10.1074/jbc.M109044200</a>.","ista":"Millán C, Luján R, Shigemoto R, Sánchez Prieto J. 2002. The inhibition of glutamate release by metabotropic glutamate receptor 7 affects both [Ca2+]c and cAMP. Evidence for a strong reduction of Ca2+ entry in single nerve terminals. Journal of Biological Chemistry. 277(16), 14092–14101.","mla":"Millán, Carmelo, et al. “The Inhibition of Glutamate Release by Metabotropic Glutamate Receptor 7 Affects Both [Ca2+]c and CAMP. Evidence for a Strong Reduction of Ca2+ Entry in Single Nerve Terminals.” <i>Journal of Biological Chemistry</i>, vol. 277, no. 16, American Society for Biochemistry and Molecular Biology, 2002, pp. 14092–101, doi:<a href=\"https://doi.org/10.1074/jbc.M109044200\">10.1074/jbc.M109044200</a>.","apa":"Millán, C., Luján, R., Shigemoto, R., &#38; Sánchez Prieto, J. (2002). The inhibition of glutamate release by metabotropic glutamate receptor 7 affects both [Ca2+]c and cAMP. Evidence for a strong reduction of Ca2+ entry in single nerve terminals. <i>Journal of Biological Chemistry</i>. American Society for Biochemistry and Molecular Biology. <a href=\"https://doi.org/10.1074/jbc.M109044200\">https://doi.org/10.1074/jbc.M109044200</a>"},"quality_controlled":"1","extern":"1","author":[{"first_name":"Carmelo","last_name":"Millán","full_name":"Millán, Carmelo"},{"last_name":"Luján","first_name":"Rafael","full_name":"Luján, Rafael"},{"id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8761-9444","full_name":"Shigemoto, Ryuichi","last_name":"Shigemoto","first_name":"Ryuichi"},{"last_name":"Sánchez Prieto","first_name":"José","full_name":"Sánchez Prieto, José"}],"tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"year":"2002","intvolume":"       277","publist_id":"4284","date_created":"2018-12-11T11:58:41Z","month":"04","status":"public","issue":"16","volume":277,"file_date_updated":"2023-07-25T10:13:16Z","article_type":"original","publisher":"American Society for Biochemistry and Molecular Biology"},{"abstract":[{"lang":"eng","text":"Taste-mGluR4, cloned from taste tissues, is a truncated variant of brain-expressed mGluR4a (brain-mGluR4), and is known to be a candidate for the receptor involved in the umami taste sense. Although the expression patterns of taste- and brain-mGluR4 mRNAs have been demonstrated, no mention has so far been made of the expression of these two mGluR4 proteins in taste tissues. The present study examined the expression of taste-mGluR4 and brain-mGluR4 proteins in rat taste tissues by using a specific antibody for mGluR4a which shared a C-terminus of both taste- and brain-mGluR4, for immunoblot analysis and immunohistochemistry. Immunoblot analysis showed that both brain-mGluR4 and taste-mGluR4 were expressed in the taste tissues. Taste-mGluR4 was not detected in the cerebellum. The immunoreactive band for brain-mGluR4 protein was much stronger than that for taste-mGluR4 protein. In the cryosections of fungiform, foliate and circumvallate papillae, the antibody against taste-mGluR4 exhibited intense labeling of the taste pores and taste hairs in all the taste buds of gustatory papillae examined; the immunoreaction to the antibody against brain-mGluR4 was more intense at the same sites of the taste buds. The portions of the taste bud cells below the taste pore and surrounding keratinocytes did not show any immunoreactivities. The results of the present study strongly suggest that, in addition to taste-mGluR4, brain-mGluR4 may function even more importantly than the former as a receptor for glutamate, i.e. the umami taste sensation."}],"publication_status":"published","_id":"2615","pmid":1,"publication":"Archives of Histology and Cytology","title":"Expression of the metabotropic glutamate receptor, mGluR4a, in the taste hairs of taste buds in rat gustatory papillae","year":"2002","quality_controlled":"1","author":[{"full_name":"Toyono, Takashi","last_name":"Toyono","first_name":"Takashi"},{"full_name":"Seta, Yuji","last_name":"Seta","first_name":"Yuji"},{"first_name":"Shinji","last_name":"Sataoka","full_name":"Sataoka, Shinji"},{"first_name":"Harumi","last_name":"Harada","orcid":"0000-0001-7429-7896","full_name":"Harada, Harumi","id":"2E55CDF2-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Morotomi, Takahiko","first_name":"Takahiko","last_name":"Morotomi"},{"full_name":"Kawano, Shintaro","first_name":"Shintaro","last_name":"Kawano"},{"last_name":"Shigemoto","first_name":"Ryuichi","orcid":"0000-0001-8761-9444","full_name":"Shigemoto, Ryuichi","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Kuniaki","last_name":"Toyoshima","full_name":"Toyoshima, Kuniaki"}],"extern":"1","citation":{"ama":"Toyono T, Seta Y, Sataoka S, et al. Expression of the metabotropic glutamate receptor, mGluR4a, in the taste hairs of taste buds in rat gustatory papillae. <i>Archives of Histology and Cytology</i>. 2002;65(1):91-96. doi:<a href=\"https://doi.org/10.1679/aohc.65.91\">10.1679/aohc.65.91</a>","ieee":"T. Toyono <i>et al.</i>, “Expression of the metabotropic glutamate receptor, mGluR4a, in the taste hairs of taste buds in rat gustatory papillae,” <i>Archives of Histology and Cytology</i>, vol. 65, no. 1. Japan Society of Histological Documentation, pp. 91–96, 2002.","chicago":"Toyono, Takashi, Yuji Seta, Shinji Sataoka, Harumi Harada, Takahiko Morotomi, Shintaro Kawano, Ryuichi Shigemoto, and Kuniaki Toyoshima. “Expression of the Metabotropic Glutamate Receptor, MGluR4a, in the Taste Hairs of Taste Buds in Rat Gustatory Papillae.” <i>Archives of Histology and Cytology</i>. Japan Society of Histological Documentation, 2002. <a href=\"https://doi.org/10.1679/aohc.65.91\">https://doi.org/10.1679/aohc.65.91</a>.","short":"T. Toyono, Y. Seta, S. Sataoka, H. Harada, T. Morotomi, S. Kawano, R. Shigemoto, K. Toyoshima, Archives of Histology and Cytology 65 (2002) 91–96.","ista":"Toyono T, Seta Y, Sataoka S, Harada H, Morotomi T, Kawano S, Shigemoto R, Toyoshima K. 2002. Expression of the metabotropic glutamate receptor, mGluR4a, in the taste hairs of taste buds in rat gustatory papillae. Archives of Histology and Cytology. 65(1), 91–96.","apa":"Toyono, T., Seta, Y., Sataoka, S., Harada, H., Morotomi, T., Kawano, S., … Toyoshima, K. (2002). Expression of the metabotropic glutamate receptor, mGluR4a, in the taste hairs of taste buds in rat gustatory papillae. <i>Archives of Histology and Cytology</i>. Japan Society of Histological Documentation. <a href=\"https://doi.org/10.1679/aohc.65.91\">https://doi.org/10.1679/aohc.65.91</a>","mla":"Toyono, Takashi, et al. “Expression of the Metabotropic Glutamate Receptor, MGluR4a, in the Taste Hairs of Taste Buds in Rat Gustatory Papillae.” <i>Archives of Histology and Cytology</i>, vol. 65, no. 1, Japan Society of Histological Documentation, 2002, pp. 91–96, doi:<a href=\"https://doi.org/10.1679/aohc.65.91\">10.1679/aohc.65.91</a>."},"status":"public","month":"01","date_created":"2018-12-11T11:58:41Z","publist_id":"4283","intvolume":"        65","article_type":"original","publisher":"Japan Society of Histological Documentation","volume":65,"issue":"1","language":[{"iso":"eng"}],"doi":"10.1679/aohc.65.91","day":"01","oa_version":"None","type":"journal_article","date_updated":"2023-07-25T10:00:15Z","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","article_processing_charge":"No","scopus_import":"1","publication_identifier":{"issn":["0914-9465"]},"page":"91 - 96","external_id":{"pmid":["12002614"]},"date_published":"2002-01-01T00:00:00Z"},{"publisher":"Oxford University Press","article_type":"original","volume":12,"issue":"6","month":"06","date_created":"2018-12-11T11:58:41Z","status":"public","intvolume":"        12","publist_id":"4282","year":"2002","citation":{"ieee":"G. López Bendito, R. Shigemoto, A. Fairén, and R. Luján, “Differential distribution of group I metabotropic glutamate receptors during rat cortical development,” <i>Cerebral Cortex</i>, vol. 12, no. 6. Oxford University Press, pp. 625–638, 2002.","ama":"López Bendito G, Shigemoto R, Fairén A, Luján R. Differential distribution of group I metabotropic glutamate receptors during rat cortical development. <i>Cerebral Cortex</i>. 2002;12(6):625-638. doi:<a href=\"https://doi.org/10.1093/cercor/12.6.625\">10.1093/cercor/12.6.625</a>","chicago":"López Bendito, Guillermina, Ryuichi Shigemoto, Alfonso Fairén, and Rafael Luján. “Differential Distribution of Group I Metabotropic Glutamate Receptors during Rat Cortical Development.” <i>Cerebral Cortex</i>. Oxford University Press, 2002. <a href=\"https://doi.org/10.1093/cercor/12.6.625\">https://doi.org/10.1093/cercor/12.6.625</a>.","short":"G. López Bendito, R. Shigemoto, A. Fairén, R. Luján, Cerebral Cortex 12 (2002) 625–638.","ista":"López Bendito G, Shigemoto R, Fairén A, Luján R. 2002. Differential distribution of group I metabotropic glutamate receptors during rat cortical development. Cerebral Cortex. 12(6), 625–638.","mla":"López Bendito, Guillermina, et al. “Differential Distribution of Group I Metabotropic Glutamate Receptors during Rat Cortical Development.” <i>Cerebral Cortex</i>, vol. 12, no. 6, Oxford University Press, 2002, pp. 625–38, doi:<a href=\"https://doi.org/10.1093/cercor/12.6.625\">10.1093/cercor/12.6.625</a>.","apa":"López Bendito, G., Shigemoto, R., Fairén, A., &#38; Luján, R. (2002). Differential distribution of group I metabotropic glutamate receptors during rat cortical development. <i>Cerebral Cortex</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/cercor/12.6.625\">https://doi.org/10.1093/cercor/12.6.625</a>"},"extern":"1","quality_controlled":"1","author":[{"full_name":"López Bendito, Guillermina","last_name":"López Bendito","first_name":"Guillermina"},{"first_name":"Ryuichi","last_name":"Shigemoto","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8761-9444","full_name":"Shigemoto, Ryuichi"},{"full_name":"Fairén, Alfonso","last_name":"Fairén","first_name":"Alfonso"},{"first_name":"Rafael","last_name":"Luján","full_name":"Luján, Rafael"}],"abstract":[{"text":"Neurons in the rat cerebral cortex are enriched in group I metabotropic glutamate receptor (mGluR) subtypes and respond to their activation during development. To understand better the mechanisms by which mGluR1 and mGluR5 mediate these effects, the goal of this study was to elucidate the expression pattern and to determine the cellular and the precise subcellular localization of these two receptor subtypes in the rat neocortex and hippocampus during late prenatal and postnatal development. At the light microscopic level, mGluR1 α and mGluR5 were first detected in the cerebral cortex with different expression levels at embryonic day E18. Thus, mGluR5 had a moderate expression, whereas mGluR1 α was detected as a diffuse and weak labeling. mGluR5 was localized in some Cajal-Retzius cells as well as in other cell types, such as pioneer neurons of the marginal zone. During postnatal development, the distribution of the receptors dramatically changed. From P0 to around P10, mGluR1α was localized in identified, transient Cajal-Retzius cells of neocortex and hippocampus, until these cells disappear. In addition, a population of interneurons localized the receptor from the second/third postnatal week. In contrast, mGluR5 was localized mainly in pyramidal cells and in some interneurons, with a neuropilar staining throughout the cerebral cortex. At the electron microscopic level, the immunoreactivity for both group I mGluR subtypes was expressed postsynaptically. Using immunogold methods, mGluR1α and mGluR5 immunoreactivities were found throughout postnatal development at the edge of postsynaptic specialization of asymmetrical synapses. These results show that the two group I mGluRs have a differential expression pattern in neocortex and hippocampus that may suggest roles for the receptors in the early processing of cortical information and in the control of cortical developmental events.","lang":"eng"}],"publication_status":"published","pmid":1,"title":"Differential distribution of group I metabotropic glutamate receptors during rat cortical development","publication":"Cerebral Cortex","_id":"2616","external_id":{"pmid":["12003862"]},"date_published":"2002-06-01T00:00:00Z","page":"625 - 638","scopus_import":"1","publication_identifier":{"issn":["1047-3211"]},"oa_version":"None","date_updated":"2023-07-25T09:54:10Z","type":"journal_article","day":"01","article_processing_charge":"No","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","acknowledgement":"The authors are grateful to Dr Ole Paulsen and Professor Kay Davies for their comments on the manuscript. We also would like to thank Dr Zoltan Molnar for his support and Mrs Lucy Jones, Ms Courtney Voelker and Mr David Dongworth for the English revision of the manuscript. This work was supported by grants from the European Community (QLG3-CT-1999-00192 to R.L.) and the Spanish Ministerio de Ciencia y Tecnología (PB97-0582-CO2-01 to A.F.).","doi":"10.1093/cercor/12.6.625","language":[{"iso":"eng"}]},{"issue":"1","page":"193 - 210","volume":542,"date_published":"2002-07-01T00:00:00Z","publisher":"Wiley-Blackwell","publist_id":"4281","intvolume":"       542","status":"public","date_created":"2018-12-11T11:58:42Z","month":"07","author":[{"first_name":"Attila","last_name":"Losonczy","full_name":"Losonczy, Attila"},{"first_name":"Limei","last_name":"Zhang","full_name":"Zhang, Limei"},{"id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","full_name":"Ryuichi Shigemoto","orcid":"0000-0001-8761-9444","last_name":"Shigemoto","first_name":"Ryuichi"},{"full_name":"Somogyi, Péter","last_name":"Somogyi","first_name":"Péter"},{"full_name":"Nusser, Zoltán","last_name":"Nusser","first_name":"Zoltán"}],"extern":1,"quality_controlled":0,"citation":{"apa":"Losonczy, A., Zhang, L., Shigemoto, R., Somogyi, P., &#38; Nusser, Z. (2002). Cell type dependence and variability in the short-term plasticity of EPSCs in identified mouse hippocampal interneurones. <i>Journal of Physiology</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1113/jphysiol.2002.020024\">https://doi.org/10.1113/jphysiol.2002.020024</a>","mla":"Losonczy, Attila, et al. “Cell Type Dependence and Variability in the Short-Term Plasticity of EPSCs in Identified Mouse Hippocampal Interneurones.” <i>Journal of Physiology</i>, vol. 542, no. 1, Wiley-Blackwell, 2002, pp. 193–210, doi:<a href=\"https://doi.org/10.1113/jphysiol.2002.020024\">10.1113/jphysiol.2002.020024</a>.","short":"A. Losonczy, L. Zhang, R. Shigemoto, P. Somogyi, Z. Nusser, Journal of Physiology 542 (2002) 193–210.","chicago":"Losonczy, Attila, Limei Zhang, Ryuichi Shigemoto, Péter Somogyi, and Zoltán Nusser. “Cell Type Dependence and Variability in the Short-Term Plasticity of EPSCs in Identified Mouse Hippocampal Interneurones.” <i>Journal of Physiology</i>. Wiley-Blackwell, 2002. <a href=\"https://doi.org/10.1113/jphysiol.2002.020024\">https://doi.org/10.1113/jphysiol.2002.020024</a>.","ista":"Losonczy A, Zhang L, Shigemoto R, Somogyi P, Nusser Z. 2002. Cell type dependence and variability in the short-term plasticity of EPSCs in identified mouse hippocampal interneurones. Journal of Physiology. 542(1), 193–210.","ama":"Losonczy A, Zhang L, Shigemoto R, Somogyi P, Nusser Z. Cell type dependence and variability in the short-term plasticity of EPSCs in identified mouse hippocampal interneurones. <i>Journal of Physiology</i>. 2002;542(1):193-210. doi:<a href=\"https://doi.org/10.1113/jphysiol.2002.020024\">10.1113/jphysiol.2002.020024</a>","ieee":"A. Losonczy, L. Zhang, R. Shigemoto, P. Somogyi, and Z. Nusser, “Cell type dependence and variability in the short-term plasticity of EPSCs in identified mouse hippocampal interneurones,” <i>Journal of Physiology</i>, vol. 542, no. 1. Wiley-Blackwell, pp. 193–210, 2002."},"main_file_link":[{"open_access":"1","url":"http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2290398/"}],"day":"01","year":"2002","type":"journal_article","date_updated":"2021-01-12T06:58:36Z","oa":1,"doi":"10.1113/jphysiol.2002.020024","_id":"2617","title":"Cell type dependence and variability in the short-term plasticity of EPSCs in identified mouse hippocampal interneurones","publication":"Journal of Physiology","publication_status":"published","abstract":[{"lang":"eng","text":"Synapses exhibit different short-term plasticity patterns and this behaviour influences information processing in neuronal networks. We tested how the short-term plasticity of excitatory postsynaptic currents (EPSCs) depends on the postsynaptic cell type, identified by axonal arborizations and molecular markers in the hippocampal CA1 area. Three distinct types of short-term synaptic behaviour (facilitating, depressing and combined facilitating-depressing) were defined by fitting a dynamic neurotransmission model to the data. Approximately 75 % of the oriens-lacunosum-moleculare (O-LM) interneurones received facilitating EPSCs, but in three of 12 O-LM cells EPSCs also showed significant depression. Over 90 % of the O-LM cells were immunopositive for somatostatin and mGluR1α and all tested cells were decorated by strongly mGluR7a positive axon terminals. Responses in eight of 12 basket cells were described well with a model involving only depression, but the other cells displayed combined facilitating-depressing EPSCs. No apparent difference was found between the plasticity of EPSCs in cholecystokinin- or parvalbumin-containing basket cells. In oriens-bistratified cells (O-Bi), two of nine cells showed facilitating EPSCs, another two depressing, and the remaining five cells combined facilitating-depressing EPSCs. Seven of 10 cells tested for somatostatin were immunopositive, but mGluR1α was detectable only in two of 11 tested cells. Furthermore, most O-Bi cells projected to the CA3 area and the subiculum, as well as outside the hippocampal formation. Postsynaptic responses to action potentials recorded in vivo from a CA1 place cell were modelled, and revealed great differences between and within cell types. Our results demonstrate that the short-term plasticity of EPSCs is cell type dependent, but with significant heterogeneity within all three interneurone populations."}]}]