[{"publication_status":"published","conference":{"end_date":"2010-04-30","location":"Raleigh, NC, United States","start_date":"2010-04-26","name":"WWW: International Conference on World Wide Web"},"doi":"10.1145/1772690.1772816","date_created":"2022-08-16T09:00:41Z","page":"1085-1086","publication":"Proceedings of the 19th international conference on World wide web ","type":"conference","oa_version":"None","language":[{"iso":"eng"}],"date_published":"2010-04-01T00:00:00Z","scopus_import":"1","article_processing_charge":"No","quality_controlled":"1","citation":{"ista":"Dütting P, Henzinger MH, Weber I. 2010. How much is your personal recommendation worth? Proceedings of the 19th international conference on World wide web . WWW: International Conference on World Wide Web, 1085–1086.","mla":"Dütting, Paul, et al. “How Much Is Your Personal Recommendation Worth?” <i>Proceedings of the 19th International Conference on World Wide Web </i>, Association for Computing Machinery, 2010, pp. 1085–86, doi:<a href=\"https://doi.org/10.1145/1772690.1772816\">10.1145/1772690.1772816</a>.","apa":"Dütting, P., Henzinger, M. H., &#38; Weber, I. (2010). How much is your personal recommendation worth? In <i>Proceedings of the 19th international conference on World wide web </i> (pp. 1085–1086). Raleigh, NC, United States: Association for Computing Machinery. <a href=\"https://doi.org/10.1145/1772690.1772816\">https://doi.org/10.1145/1772690.1772816</a>","chicago":"Dütting, Paul, Monika H Henzinger, and Ingmar Weber. “How Much Is Your Personal Recommendation Worth?” In <i>Proceedings of the 19th International Conference on World Wide Web </i>, 1085–86. Association for Computing Machinery, 2010. <a href=\"https://doi.org/10.1145/1772690.1772816\">https://doi.org/10.1145/1772690.1772816</a>.","short":"P. Dütting, M.H. Henzinger, I. Weber, in:, Proceedings of the 19th International Conference on World Wide Web , Association for Computing Machinery, 2010, pp. 1085–1086.","ieee":"P. Dütting, M. H. Henzinger, and I. Weber, “How much is your personal recommendation worth?,” in <i>Proceedings of the 19th international conference on World wide web </i>, Raleigh, NC, United States, 2010, pp. 1085–1086.","ama":"Dütting P, Henzinger MH, Weber I. How much is your personal recommendation worth? In: <i>Proceedings of the 19th International Conference on World Wide Web </i>. Association for Computing Machinery; 2010:1085-1086. doi:<a href=\"https://doi.org/10.1145/1772690.1772816\">10.1145/1772690.1772816</a>"},"date_updated":"2023-02-17T10:14:10Z","abstract":[{"lang":"eng","text":"Suppose you buy a new laptop and, simply because you like it so much, you recommend it to friends, encouraging them to purchase it as well. What would be an adequate price for the vendor of the laptop to pay for your recommendation?\r\n\r\nPersonal recommendations like this are of considerable commercial interest, but unlike in sponsored search auctions there can be no truthful prices. Despite this \"lack of truthfulness\" the vendor of the product might still decide to pay you for recommendation e.g. because she wants to (i) provide you with an additional incentive to actually recommend her or to (ii) increase your satisfaction and/or brand loyalty. This leads us to investigate a pricing scheme based on the Shapley value [5] that satisfies certain \"axioms of fairness\". We find that it is vulnerable to manipulations and show how to overcome these difficulties using the anonymity-proof Shapley value of [4]."}],"day":"01","year":"2010","extern":"1","author":[{"last_name":"Dütting","first_name":"Paul","full_name":"Dütting, Paul"},{"full_name":"Henzinger, Monika H","last_name":"Henzinger","id":"540c9bbd-f2de-11ec-812d-d04a5be85630","orcid":"0000-0002-5008-6530","first_name":"Monika H"},{"full_name":"Weber, Ingmar","first_name":"Ingmar","last_name":"Weber"}],"_id":"11863","publisher":"Association for Computing Machinery","status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"How much is your personal recommendation worth?","publication_identifier":{"isbn":["9781605587998"]},"month":"04"},{"scopus_import":"1","article_processing_charge":"No","article_type":"original","citation":{"chicago":"Henzinger, Monika H, Jacob Suñol, and Ingmar Weber. “The Stability of the H-Index.” <i>Scientometrics</i>. Springer Nature, 2010. <a href=\"https://doi.org/10.1007/s11192-009-0098-7\">https://doi.org/10.1007/s11192-009-0098-7</a>.","mla":"Henzinger, Monika H., et al. “The Stability of the H-Index.” <i>Scientometrics</i>, vol. 84, no. 2, Springer Nature, 2010, pp. 465–79, doi:<a href=\"https://doi.org/10.1007/s11192-009-0098-7\">10.1007/s11192-009-0098-7</a>.","apa":"Henzinger, M. H., Suñol, J., &#38; Weber, I. (2010). The stability of the h-index. <i>Scientometrics</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s11192-009-0098-7\">https://doi.org/10.1007/s11192-009-0098-7</a>","ista":"Henzinger MH, Suñol J, Weber I. 2010. The stability of the h-index. Scientometrics. 84(2), 465–479.","ama":"Henzinger MH, Suñol J, Weber I. The stability of the h-index. <i>Scientometrics</i>. 2010;84(2):465-479. doi:<a href=\"https://doi.org/10.1007/s11192-009-0098-7\">10.1007/s11192-009-0098-7</a>","ieee":"M. H. Henzinger, J. Suñol, and I. Weber, “The stability of the h-index,” <i>Scientometrics</i>, vol. 84, no. 2. Springer Nature, pp. 465–479, 2010.","short":"M.H. Henzinger, J. Suñol, I. Weber, Scientometrics 84 (2010) 465–479."},"volume":84,"intvolume":"        84","quality_controlled":"1","date_created":"2022-08-17T07:51:23Z","page":"465-479","publication":"Scientometrics","publication_status":"published","doi":"10.1007/s11192-009-0098-7","language":[{"iso":"eng"}],"date_published":"2010-08-01T00:00:00Z","oa_version":"None","type":"journal_article","title":"The stability of the h-index","publication_identifier":{"eissn":["1588-2861"],"issn":["0138-9130"]},"publisher":"Springer Nature","status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","month":"08","day":"01","extern":"1","year":"2010","date_updated":"2023-02-17T14:09:51Z","issue":"2","abstract":[{"text":"Over the last years the h-index has gained popularity as a measure for comparing the impact of scientists. We investigate if ranking according to the h-index is stable with respect to (i) different choices of citation databases, (ii) normalizing citation counts by the number of authors or by removing self-citations, (iii) small amounts of noise created by randomly removing citations or publications and (iv) small changes in the definition of the index. In experiments for 5,283 computer scientists and 1,354 physicists we show that although the ranking of the h-index is stable under most of these changes, it is unstable when different databases are used. Therefore, comparisons based on the h-index should only be trusted when the rankings of multiple citation databases agree.","lang":"eng"}],"_id":"11885","author":[{"orcid":"0000-0002-5008-6530","first_name":"Monika H","id":"540c9bbd-f2de-11ec-812d-d04a5be85630","last_name":"Henzinger","full_name":"Henzinger, Monika H"},{"first_name":"Jacob","last_name":"Suñol","full_name":"Suñol, Jacob"},{"full_name":"Weber, Ingmar","first_name":"Ingmar","last_name":"Weber"}]},{"pmid":1,"day":"15","extern":"1","author":[{"full_name":"Pieber, Bartholomäus","first_name":"Bartholomäus","orcid":"0000-0001-8689-388X","id":"93e5e5b2-0da6-11ed-8a41-af589a024726","last_name":"Pieber"},{"last_name":"Schober","first_name":"Sigurd","full_name":"Schober, Sigurd"},{"first_name":"Christoph","last_name":"Goebl","full_name":"Goebl, Christoph"},{"first_name":"Martin","last_name":"Mittelbach","full_name":"Mittelbach, Martin"}],"publisher":"Elsevier","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Novel sensitive determination of steryl glycosides in biodiesel by gas chromatography-mass spectroscopy","page":"6555-6561","date_created":"2022-08-25T10:43:43Z","publication":"Journal of Chromatography A","type":"journal_article","language":[{"iso":"eng"}],"article_type":"original","article_processing_charge":"No","external_id":{"pmid":["20846658"]},"volume":1217,"quality_controlled":"1","date_updated":"2023-02-21T10:09:59Z","abstract":[{"lang":"eng","text":"A new method was developed for the quantitative analysis of steryl glycosides in biodiesel (fatty acid methyl esters). This method is much more sensitive than existing methods and has minimum limits of quantification of 50 μg/kg, compared to previously published minimum limits of quantification of about 15 mg/kg. The analysis is based on gas chromatography–mass spectroscopy determination of simple pre-treated and silylated samples via single ion monitoring at 147, 204, 217 m/z, which are specific ions for the silylated sugar moiety. Quantification was carried out using cholesteryl β-d-glucopyranoside as internal standard. The modified synthesis and purification of the internal standard is also presented as well as the characterization by NMR and mass spectroscopy. The advantage of the method compared with other approaches is the simplified sample preparation avoiding extra pre-treatment steps coupled with complete derivatization of the sugar hydroxyl groups by using N,O-bis(trimethylsilyl)acetamide with 5% trimethylchlorosilane as derivatization reagent. On the given conditions high recovery rates ≥89% can be obtained. Evaluation of lab specific variance and intermediate precision underline the robustness of the method which will be further assessed by Round robin tests."}],"issue":"42","year":"2010","_id":"11975","status":"public","publication_identifier":{"issn":["0021-9673"]},"month":"10","publication_status":"published","doi":"10.1016/j.chroma.2010.08.006","oa_version":"None","date_published":"2010-10-15T00:00:00Z","scopus_import":"1","citation":{"ieee":"B. Pieber, S. Schober, C. Goebl, and M. Mittelbach, “Novel sensitive determination of steryl glycosides in biodiesel by gas chromatography-mass spectroscopy,” <i>Journal of Chromatography A</i>, vol. 1217, no. 42. Elsevier, pp. 6555–6561, 2010.","ama":"Pieber B, Schober S, Goebl C, Mittelbach M. Novel sensitive determination of steryl glycosides in biodiesel by gas chromatography-mass spectroscopy. <i>Journal of Chromatography A</i>. 2010;1217(42):6555-6561. doi:<a href=\"https://doi.org/10.1016/j.chroma.2010.08.006\">10.1016/j.chroma.2010.08.006</a>","short":"B. Pieber, S. Schober, C. Goebl, M. Mittelbach, Journal of Chromatography A 1217 (2010) 6555–6561.","mla":"Pieber, Bartholomäus, et al. “Novel Sensitive Determination of Steryl Glycosides in Biodiesel by Gas Chromatography-Mass Spectroscopy.” <i>Journal of Chromatography A</i>, vol. 1217, no. 42, Elsevier, 2010, pp. 6555–61, doi:<a href=\"https://doi.org/10.1016/j.chroma.2010.08.006\">10.1016/j.chroma.2010.08.006</a>.","apa":"Pieber, B., Schober, S., Goebl, C., &#38; Mittelbach, M. (2010). Novel sensitive determination of steryl glycosides in biodiesel by gas chromatography-mass spectroscopy. <i>Journal of Chromatography A</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.chroma.2010.08.006\">https://doi.org/10.1016/j.chroma.2010.08.006</a>","ista":"Pieber B, Schober S, Goebl C, Mittelbach M. 2010. Novel sensitive determination of steryl glycosides in biodiesel by gas chromatography-mass spectroscopy. Journal of Chromatography A. 1217(42), 6555–6561.","chicago":"Pieber, Bartholomäus, Sigurd Schober, Christoph Goebl, and Martin Mittelbach. “Novel Sensitive Determination of Steryl Glycosides in Biodiesel by Gas Chromatography-Mass Spectroscopy.” <i>Journal of Chromatography A</i>. Elsevier, 2010. <a href=\"https://doi.org/10.1016/j.chroma.2010.08.006\">https://doi.org/10.1016/j.chroma.2010.08.006</a>."},"intvolume":"      1217"},{"author":[{"full_name":"Feng, Xiaoqi","first_name":"Xiaoqi","orcid":"0000-0002-4008-1234","id":"e0164712-22ee-11ed-b12a-d80fcdf35958","last_name":"Feng"},{"last_name":"Dickinson","first_name":"Hugh G.","full_name":"Dickinson, Hugh G."}],"pmid":1,"acknowledgement":"We thank the following for providing mutant lines and reagents: Hong Ma, De Ye, Sacco De Vries, and Rod Scott for providing the pA9::Barnase lines and information on A9 expression patterns. Carla Galinha and Paolo Piazza gave valuable help with in situ hybridisation and qRT-PCR, respectively, and we acknowledge Qing Zhang, Helen Prescott and Matthew Dicks for providing excellent technical assistance. We are indebted to Miltos Tsiantis and Angela Hay for helpful discussion, and the research was funded by Oxford University through a Clarendon Scholarship to X.F., with additional financial support from Magdalen College (Oxford).","day":"15","extern":"1","publisher":"The Company of Biologists","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Tapetal cell fate, lineage and proliferation in the Arabidopsis anther","type":"journal_article","language":[{"iso":"eng"}],"department":[{"_id":"XiFe"}],"page":"2409-2416","date_created":"2023-01-16T09:21:54Z","publication":"Development","external_id":{"pmid":["20570940"]},"volume":137,"keyword":["Developmental Biology","Molecular Biology","Anther Tapetum","Arabidopsis","Cell Fate Establishment","EMS1","Reproductive Cell Lineage"],"quality_controlled":"1","article_type":"original","article_processing_charge":"No","_id":"12199","date_updated":"2023-05-08T10:57:11Z","issue":"14","abstract":[{"lang":"eng","text":"The four microsporangia of the flowering plant anther develop from archesporial cells in the L2 of the primordium. Within each microsporangium, developing microsporocytes are surrounded by concentric monolayers of tapetal, middle layer and endothecial cells. How this intricate array of tissues, each containing relatively few cells, is established in an organ possessing no formal meristems is poorly understood. We describe here the pivotal role of the LRR receptor kinase EXCESS MICROSPOROCYTES 1 (EMS1) in forming the monolayer of tapetal nurse cells in Arabidopsis. Unusually for plants, tapetal cells are specified very early in development, and are subsequently stimulated to proliferate by a receptor-like kinase (RLK) complex that includes EMS1. Mutations in members of this EMS1 signalling complex and its putative ligand result in male-sterile plants in which tapetal initials fail to proliferate. Surprisingly, these cells continue to develop, isolated at the locular periphery. Mutant and wild-type microsporangia expand at similar rates and the ‘tapetal’ space at the periphery of mutant locules becomes occupied by microsporocytes. However, induction of late expression of EMS1 in the few tapetal initials in ems1 plants results in their proliferation to generate a functional tapetum, and this proliferation suppresses microsporocyte number. Our experiments also show that integrity of the tapetal monolayer is crucial for the maintenance of the polarity of divisions within it. This unexpected autonomy of the tapetal ‘lineage’ is discussed in the context of tissue development in complex plant organs, where constancy in size, shape and cell number is crucial."}],"year":"2010","month":"07","status":"public","publication_identifier":{"issn":["1477-9129","0950-1991"]},"oa_version":"None","date_published":"2010-07-15T00:00:00Z","publication_status":"published","doi":"10.1242/dev.049320","citation":{"chicago":"Feng, Xiaoqi, and Hugh G. Dickinson. “Tapetal Cell Fate, Lineage and Proliferation in the Arabidopsis Anther.” <i>Development</i>. The Company of Biologists, 2010. <a href=\"https://doi.org/10.1242/dev.049320\">https://doi.org/10.1242/dev.049320</a>.","mla":"Feng, Xiaoqi, and Hugh G. Dickinson. “Tapetal Cell Fate, Lineage and Proliferation in the Arabidopsis Anther.” <i>Development</i>, vol. 137, no. 14, The Company of Biologists, 2010, pp. 2409–16, doi:<a href=\"https://doi.org/10.1242/dev.049320\">10.1242/dev.049320</a>.","ista":"Feng X, Dickinson HG. 2010. Tapetal cell fate, lineage and proliferation in the Arabidopsis anther. Development. 137(14), 2409–2416.","apa":"Feng, X., &#38; Dickinson, H. G. (2010). Tapetal cell fate, lineage and proliferation in the Arabidopsis anther. <i>Development</i>. The Company of Biologists. <a href=\"https://doi.org/10.1242/dev.049320\">https://doi.org/10.1242/dev.049320</a>","short":"X. Feng, H.G. Dickinson, Development 137 (2010) 2409–2416.","ieee":"X. Feng and H. G. Dickinson, “Tapetal cell fate, lineage and proliferation in the Arabidopsis anther,” <i>Development</i>, vol. 137, no. 14. The Company of Biologists, pp. 2409–2416, 2010.","ama":"Feng X, Dickinson HG. Tapetal cell fate, lineage and proliferation in the Arabidopsis anther. <i>Development</i>. 2010;137(14):2409-2416. doi:<a href=\"https://doi.org/10.1242/dev.049320\">10.1242/dev.049320</a>"},"intvolume":"       137","scopus_import":"1"},{"pmid":1,"extern":"1","day":"22","author":[{"full_name":"Feng, Xiaoqi","first_name":"Xiaoqi","orcid":"0000-0002-4008-1234","last_name":"Feng","id":"e0164712-22ee-11ed-b12a-d80fcdf35958"},{"first_name":"Hugh G.","last_name":"Dickinson","full_name":"Dickinson, Hugh G."}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"Portland Press Ltd.","title":"Cell–cell interactions during patterning of the <i>Arabidopsis</i> anther","publication":"Biochemical Society Transactions","page":"571-576","date_created":"2023-01-16T09:22:18Z","type":"journal_article","department":[{"_id":"XiFe"}],"language":[{"iso":"eng"}],"article_processing_charge":"No","article_type":"original","quality_controlled":"1","keyword":["Biochemistry","Anther Development","Arabidopsis","Cell Fate","Microsporangium","Polarity","Receptor Kinase"],"volume":38,"external_id":{"pmid":["20298223"]},"abstract":[{"lang":"eng","text":"Key steps in the evolution of the angiosperm anther include the patterning of the concentrically organized microsporangium and the incorporation of four such microsporangia into a leaf-like structure. Mutant studies in the model plant Arabidopsis thaliana are leading to an increasingly accurate picture of (i) the cell lineages culminating in the different cell types present in the microsporangium (the microsporocytes, the tapetum, and the middle and endothecial layers), and (ii) some of the genes responsible for specifying their fates. However, the processes that confer polarity on the developing anther and position the microsporangia within it remain unclear. Certainly, data from a range of experimental strategies suggest that hormones play a central role in establishing polarity and the patterning of the anther initial, and may be responsible for locating the microsporangia. But the fact that microsporangia were originally positioned externally suggests that their development is likely to be autonomous, perhaps with the reproductive cells generating signals controlling the growth and division of the investing anther epidermis. These possibilities are discussed in the context of the expression of genes which initiate and maintain male and female reproductive development, and in the perspective of our current views of anther evolution."}],"issue":"2","date_updated":"2023-05-08T10:57:59Z","year":"2010","_id":"12200","status":"public","publication_identifier":{"issn":["0300-5127","1470-8752"]},"month":"03","doi":"10.1042/bst0380571","publication_status":"published","oa_version":"None","date_published":"2010-03-22T00:00:00Z","scopus_import":"1","citation":{"apa":"Feng, X., &#38; Dickinson, H. G. (2010). Cell–cell interactions during patterning of the <i>Arabidopsis</i> anther. <i>Biochemical Society Transactions</i>. Portland Press Ltd. <a href=\"https://doi.org/10.1042/bst0380571\">https://doi.org/10.1042/bst0380571</a>","mla":"Feng, Xiaoqi, and Hugh G. Dickinson. “Cell–Cell Interactions during Patterning of the <i>Arabidopsis</i> Anther.” <i>Biochemical Society Transactions</i>, vol. 38, no. 2, Portland Press Ltd., 2010, pp. 571–76, doi:<a href=\"https://doi.org/10.1042/bst0380571\">10.1042/bst0380571</a>.","ista":"Feng X, Dickinson HG. 2010. Cell–cell interactions during patterning of the <i>Arabidopsis</i> anther. Biochemical Society Transactions. 38(2), 571–576.","chicago":"Feng, Xiaoqi, and Hugh G. Dickinson. “Cell–Cell Interactions during Patterning of the <i>Arabidopsis</i> Anther.” <i>Biochemical Society Transactions</i>. Portland Press Ltd., 2010. <a href=\"https://doi.org/10.1042/bst0380571\">https://doi.org/10.1042/bst0380571</a>.","short":"X. Feng, H.G. Dickinson, Biochemical Society Transactions 38 (2010) 571–576.","ieee":"X. Feng and H. G. Dickinson, “Cell–cell interactions during patterning of the <i>Arabidopsis</i> anther,” <i>Biochemical Society Transactions</i>, vol. 38, no. 2. Portland Press Ltd., pp. 571–576, 2010.","ama":"Feng X, Dickinson HG. Cell–cell interactions during patterning of the <i>Arabidopsis</i> anther. <i>Biochemical Society Transactions</i>. 2010;38(2):571-576. doi:<a href=\"https://doi.org/10.1042/bst0380571\">10.1042/bst0380571</a>"},"intvolume":"        38"},{"extern":"1","day":"01","author":[{"full_name":"Pellicciotti, Francesca","last_name":"Pellicciotti","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70","first_name":"Francesca"},{"first_name":"A.","last_name":"Bauder","full_name":"Bauder, A."},{"last_name":"Parola","first_name":"M.","full_name":"Parola, M."}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"American Geophysical Union","title":"Effect of glaciers on streamflow trends in the Swiss Alps","publication":"Water Resources Research","date_created":"2023-02-20T08:18:27Z","type":"journal_article","language":[{"iso":"eng"}],"article_processing_charge":"No","article_type":"original","quality_controlled":"1","keyword":["Water Science and Technology"],"volume":46,"abstract":[{"text":"Daily streamflow from stations close to five Swiss glaciers is analyzed for trends with the Mann-Kendall test. We consider a common period of record (1974–2004) and longer periods based on data availability. The trend statistical significance is tested on annual and seasonal bases. We also examine changes in precipitation, temperature, and snow cover characteristics. Highly glacierized basins show statistically significant positive trends in annual streamflow caused by increasing streamflow in spring and summer. Trends are more numerous and stronger at lower and mid than at the upper quantiles. The basin characterized by lower glacier coverage, conversely, does not exhibit consistently statistically significant trends. Changes in precipitation are not sufficient to explain the observed streamflow trends. Air temperature sees an increase in mean, minimum, and maximum values at all sites. Variations in the seasonal snow accumulation and ablation process are evident. Solid precipitation is decreasing at all sites and trends may be due to a shift from snowfall into rainfall. Mean snow depth is also decreasing, and its duration is getting shorter because of a decrease in solid precipitation and enhanced melting. Trend magnitude attenuates with longer time series. Contrasting trends are detected for different subperiods in the last 70 years: statistically significant negative trends are observed in the periods 1944–1974 and 1954–1984 for Aletschgletscher, in contrast with the results for the common period. These trends are explained by different rates of ice volume changes, and the sign of trends is clearly related to phases of positive or negative glacier mass balance.","lang":"eng"}],"issue":"10","date_updated":"2023-02-20T09:39:29Z","year":"2010","article_number":"W10522","_id":"12653","status":"public","publication_identifier":{"eissn":["1944-7973"],"issn":["0043-1397"]},"oa":1,"month":"10","doi":"10.1029/2009wr009039","publication_status":"published","oa_version":"Published Version","date_published":"2010-10-01T00:00:00Z","main_file_link":[{"url":"https://doi.org/10.1029/2009WR009039","open_access":"1"}],"scopus_import":"1","intvolume":"        46","citation":{"chicago":"Pellicciotti, Francesca, A. Bauder, and M. Parola. “Effect of Glaciers on Streamflow Trends in the Swiss Alps.” <i>Water Resources Research</i>. American Geophysical Union, 2010. <a href=\"https://doi.org/10.1029/2009wr009039\">https://doi.org/10.1029/2009wr009039</a>.","mla":"Pellicciotti, Francesca, et al. “Effect of Glaciers on Streamflow Trends in the Swiss Alps.” <i>Water Resources Research</i>, vol. 46, no. 10, W10522, American Geophysical Union, 2010, doi:<a href=\"https://doi.org/10.1029/2009wr009039\">10.1029/2009wr009039</a>.","apa":"Pellicciotti, F., Bauder, A., &#38; Parola, M. (2010). Effect of glaciers on streamflow trends in the Swiss Alps. <i>Water Resources Research</i>. American Geophysical Union. <a href=\"https://doi.org/10.1029/2009wr009039\">https://doi.org/10.1029/2009wr009039</a>","ista":"Pellicciotti F, Bauder A, Parola M. 2010. Effect of glaciers on streamflow trends in the Swiss Alps. Water Resources Research. 46(10), W10522.","ama":"Pellicciotti F, Bauder A, Parola M. Effect of glaciers on streamflow trends in the Swiss Alps. <i>Water Resources Research</i>. 2010;46(10). doi:<a href=\"https://doi.org/10.1029/2009wr009039\">10.1029/2009wr009039</a>","ieee":"F. Pellicciotti, A. Bauder, and M. Parola, “Effect of glaciers on streamflow trends in the Swiss Alps,” <i>Water Resources Research</i>, vol. 46, no. 10. American Geophysical Union, 2010.","short":"F. Pellicciotti, A. Bauder, M. Parola, Water Resources Research 46 (2010)."}},{"status":"public","publisher":"Nature Publishing Group","title":"ON and off pathways in Drosophila motion vision","month":"11","date_updated":"2021-01-12T06:49:44Z","issue":"7321","abstract":[{"text":"Motion vision is a major function of all visual systems, yet the underlying neural mechanisms and circuits are still elusive. In the lamina, the first optic neuropile of Drosophila melanogaster, photoreceptor signals split into five parallel pathways, L1-L5. Here we examine how these pathways contribute to visual motion detection by combining genetic block and reconstitution of neural activity in different lamina cell types with whole-cell recordings from downstream motion-sensitive neurons. We find reduced responses to moving gratings if L1 or L2 is blocked; however, reconstitution of photoreceptor input to only L1 or L2 results in wild-type responses. Thus, the first experiment indicates the necessity of both pathways, whereas the second indicates sufficiency of each single pathway. This contradiction can be explained by electrical coupling between L1 and L2, allowing for activation of both pathways even when only one of them receives photoreceptor input. A fundamental difference between the L1 pathway and the L2 pathway is uncovered when blocking L1 or L2 output while presenting moving edges of positive (ON) or negative (OFF) contrast polarity: blocking L1 eliminates the response to moving ON edges, whereas blocking L2 eliminates the response to moving OFF edges. Thus, similar to the segregation of photoreceptor signals in ON and OFF bipolar cell pathways in the vertebrate retina, photoreceptor signals segregate into ON-L1 and OFF-L2 channels in the lamina of Drosophila.","lang":"eng"}],"day":"11","year":"2010","extern":1,"author":[{"full_name":"Maximilian Jösch","first_name":"Maximilian A","orcid":"0000-0002-3937-1330","id":"2BD278E6-F248-11E8-B48F-1D18A9856A87","last_name":"Jösch"},{"full_name":"Schnell, Bettina","first_name":"Bettina","last_name":"Schnell"},{"last_name":"Raghu","first_name":"Shamprasad","full_name":"Raghu, Shamprasad V"},{"full_name":"Reiff, Dierk F","last_name":"Reiff","first_name":"Dierk"},{"last_name":"Borst","first_name":"Alexander","full_name":"Borst, Alexander"}],"_id":"1300","publist_id":"5970","citation":{"chicago":"Jösch, Maximilian A, Bettina Schnell, Shamprasad Raghu, Dierk Reiff, and Alexander Borst. “ON and off Pathways in Drosophila Motion Vision.” <i>Nature</i>. Nature Publishing Group, 2010. <a href=\"https://doi.org/10.1038/nature09545\">https://doi.org/10.1038/nature09545</a>.","ista":"Jösch MA, Schnell B, Raghu S, Reiff D, Borst A. 2010. ON and off pathways in Drosophila motion vision. Nature. 468(7321), 300–304.","apa":"Jösch, M. A., Schnell, B., Raghu, S., Reiff, D., &#38; Borst, A. (2010). ON and off pathways in Drosophila motion vision. <i>Nature</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/nature09545\">https://doi.org/10.1038/nature09545</a>","mla":"Jösch, Maximilian A., et al. “ON and off Pathways in Drosophila Motion Vision.” <i>Nature</i>, vol. 468, no. 7321, Nature Publishing Group, 2010, pp. 300–04, doi:<a href=\"https://doi.org/10.1038/nature09545\">10.1038/nature09545</a>.","short":"M.A. Jösch, B. Schnell, S. Raghu, D. Reiff, A. Borst, Nature 468 (2010) 300–304.","ama":"Jösch MA, Schnell B, Raghu S, Reiff D, Borst A. ON and off pathways in Drosophila motion vision. <i>Nature</i>. 2010;468(7321):300-304. doi:<a href=\"https://doi.org/10.1038/nature09545\">10.1038/nature09545</a>","ieee":"M. A. Jösch, B. Schnell, S. Raghu, D. Reiff, and A. Borst, “ON and off pathways in Drosophila motion vision,” <i>Nature</i>, vol. 468, no. 7321. Nature Publishing Group, pp. 300–304, 2010."},"intvolume":"       468","quality_controlled":0,"volume":468,"publication_status":"published","doi":"10.1038/nature09545","page":"300 - 304","date_created":"2018-12-11T11:51:14Z","publication":"Nature","type":"journal_article","date_published":"2010-11-11T00:00:00Z"},{"status":"public","publication_identifier":{"eissn":["1522-1598"],"issn":[" 0022-3077"]},"month":"03","issue":"3","abstract":[{"text":"Motion vision is essential for navigating through the environment. Due to its genetic amenability, the fruit fly Drosophila has been serving for a lengthy period as a model organism for studying optomotor behavior as elicited by large-field horizontal motion. However, the neurons underlying the control of this behavior have not been studied in Drosophila so far. Here we report the first whole cell recordings from three cells of the horizontal system (HSN, HSE, and HSS) in the lobula plate of Drosophila. All three HS cells are tuned to large-field horizontal motion in a direction-selective way; they become excited by front-to-back motion and inhibited by back-to-front motion in the ipsilateral field of view. The response properties of HS cells such as contrast and velocity dependence are in accordance with the correlation-type model of motion detection. Neurobiotin injection suggests extensive coupling among ipsilateral HS cells and additional coupling to tangential cells that have their dendrites in the contralateral hemisphere of the brain. This connectivity scheme accounts for the complex layout of their receptive fields and explains their sensitivity both to ipsilateral and to contralateral motion. Thus the main response properties of Drosophila HS cells are strikingly similar to the responses of their counterparts in the blowfly Calliphora, although we found substantial differences with respect to their dendritic structure and connectivity. This long-awaited functional characterization of HS cells in Drosophila provides the basis for the future dissection of optomotor behavior and the underlying neural circuitry by combining genetics, physiology, and behavior.","lang":"eng"}],"date_updated":"2021-01-12T06:49:44Z","year":"2010","_id":"1301","intvolume":"       103","citation":{"ieee":"B. Schnell <i>et al.</i>, “Processing of horizontal optic flow in three visual interneurons of the Drosophila brain,” <i>Journal of Neurophysiology</i>, vol. 103, no. 3. American Physiological Society, pp. 1646–1657, 2010.","ama":"Schnell B, Jösch MA, Förstner F, et al. Processing of horizontal optic flow in three visual interneurons of the Drosophila brain. <i>Journal of Neurophysiology</i>. 2010;103(3):1646-1657. doi:<a href=\"https://doi.org/10.1152/jn.00950.2009\">10.1152/jn.00950.2009</a>","short":"B. Schnell, M.A. Jösch, F. Förstner, S. Raghu, H. Otsuna, K. Ito, A. Borst, D. Reiff, Journal of Neurophysiology 103 (2010) 1646–1657.","chicago":"Schnell, Bettina, Maximilian A Jösch, Friedrich Förstner, Shamprasad Raghu, Hideo Otsuna, Kei Ito, Alexander Borst, and Dierk Reiff. “Processing of Horizontal Optic Flow in Three Visual Interneurons of the Drosophila Brain.” <i>Journal of Neurophysiology</i>. American Physiological Society, 2010. <a href=\"https://doi.org/10.1152/jn.00950.2009\">https://doi.org/10.1152/jn.00950.2009</a>.","ista":"Schnell B, Jösch MA, Förstner F, Raghu S, Otsuna H, Ito K, Borst A, Reiff D. 2010. Processing of horizontal optic flow in three visual interneurons of the Drosophila brain. Journal of Neurophysiology. 103(3), 1646–1657.","apa":"Schnell, B., Jösch, M. A., Förstner, F., Raghu, S., Otsuna, H., Ito, K., … Reiff, D. (2010). Processing of horizontal optic flow in three visual interneurons of the Drosophila brain. <i>Journal of Neurophysiology</i>. American Physiological Society. <a href=\"https://doi.org/10.1152/jn.00950.2009\">https://doi.org/10.1152/jn.00950.2009</a>","mla":"Schnell, Bettina, et al. “Processing of Horizontal Optic Flow in Three Visual Interneurons of the Drosophila Brain.” <i>Journal of Neurophysiology</i>, vol. 103, no. 3, American Physiological Society, 2010, pp. 1646–57, doi:<a href=\"https://doi.org/10.1152/jn.00950.2009\">10.1152/jn.00950.2009</a>."},"doi":"10.1152/jn.00950.2009","publication_status":"published","oa_version":"None","date_published":"2010-03-01T00:00:00Z","user_id":"D865714E-FA4E-11E9-B85B-F5C5E5697425","publisher":"American Physiological Society","title":"Processing of horizontal optic flow in three visual interneurons of the Drosophila brain","pmid":1,"acknowledgement":"This work was supported by the Max-Planck-Society and by a Human Frontier Science Program grant to K. Ito, A. Borst, and B. Nelson.","extern":"1","day":"01","author":[{"full_name":"Schnell, Bettina","first_name":"Bettina","last_name":"Schnell"},{"full_name":"Jösch, Maximilian A","first_name":"Maximilian A","orcid":"0000-0002-3937-1330","last_name":"Jösch","id":"2BD278E6-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Förstner, Friedrich","last_name":"Förstner","first_name":"Friedrich"},{"last_name":"Raghu","first_name":"Shamprasad","full_name":"Raghu, Shamprasad"},{"first_name":"Hideo","last_name":"Otsuna","full_name":"Otsuna, Hideo"},{"full_name":"Ito, Kei","first_name":"Kei","last_name":"Ito"},{"first_name":"Alexander","last_name":"Borst","full_name":"Borst, Alexander"},{"full_name":"Reiff, Dierk","first_name":"Dierk","last_name":"Reiff"}],"article_type":"original","article_processing_charge":"No","publist_id":"5971","volume":103,"quality_controlled":"1","external_id":{"pmid":["20089816"]},"publication":"Journal of Neurophysiology","date_created":"2018-12-11T11:51:14Z","page":"1646 - 1657","type":"journal_article","language":[{"iso":"eng"}]},{"author":[{"full_name":"Rosas, Ulises","last_name":"Rosas","first_name":"Ulises"},{"first_name":"Nicholas H","orcid":"0000-0002-8548-5240","id":"4880FE40-F248-11E8-B48F-1D18A9856A87","last_name":"Barton","full_name":"Barton, Nicholas H"},{"full_name":"Copsey, Lucy","first_name":"Lucy","last_name":"Copsey"},{"full_name":"Barbier De Reuille, Pierre","last_name":"Barbier De Reuille","first_name":"Pierre"},{"full_name":"Coen, Enrico","last_name":"Coen","first_name":"Enrico"}],"_id":"9764","date_updated":"2023-02-23T11:42:17Z","year":"2010","day":"20","month":"07","user_id":"6785fbc1-c503-11eb-8a32-93094b40e1cf","status":"public","publisher":"Public Library of Science","title":"Heterosis and the drift load","type":"research_data_reference","oa_version":"Published Version","department":[{"_id":"NiBa"}],"date_published":"2010-07-20T00:00:00Z","doi":"10.1371/journal.pbio.1000429.s003","date_created":"2021-08-02T09:45:39Z","citation":{"ieee":"U. Rosas, N. H. Barton, L. Copsey, P. Barbier De Reuille, and E. Coen, “Heterosis and the drift load.” Public Library of Science, 2010.","ama":"Rosas U, Barton NH, Copsey L, Barbier De Reuille P, Coen E. Heterosis and the drift load. 2010. doi:<a href=\"https://doi.org/10.1371/journal.pbio.1000429.s003\">10.1371/journal.pbio.1000429.s003</a>","short":"U. Rosas, N.H. Barton, L. Copsey, P. Barbier De Reuille, E. Coen, (2010).","mla":"Rosas, Ulises, et al. <i>Heterosis and the Drift Load</i>. Public Library of Science, 2010, doi:<a href=\"https://doi.org/10.1371/journal.pbio.1000429.s003\">10.1371/journal.pbio.1000429.s003</a>.","ista":"Rosas U, Barton NH, Copsey L, Barbier De Reuille P, Coen E. 2010. Heterosis and the drift load, Public Library of Science, <a href=\"https://doi.org/10.1371/journal.pbio.1000429.s003\">10.1371/journal.pbio.1000429.s003</a>.","apa":"Rosas, U., Barton, N. H., Copsey, L., Barbier De Reuille, P., &#38; Coen, E. (2010). Heterosis and the drift load. Public Library of Science. <a href=\"https://doi.org/10.1371/journal.pbio.1000429.s003\">https://doi.org/10.1371/journal.pbio.1000429.s003</a>","chicago":"Rosas, Ulises, Nicholas H Barton, Lucy Copsey, Pierre Barbier De Reuille, and Enrico Coen. “Heterosis and the Drift Load.” Public Library of Science, 2010. <a href=\"https://doi.org/10.1371/journal.pbio.1000429.s003\">https://doi.org/10.1371/journal.pbio.1000429.s003</a>."},"related_material":{"record":[{"id":"3779","relation":"used_in_publication","status":"public"}]},"article_processing_charge":"No"},{"extern":1,"year":"2010","day":"01","issue":"3","acknowledgement":"This research was supported by the Swiss National Science Foundation. This paper is an extended and revised version of our previous work on model checking transactional memories.","abstract":[{"text":"Model checking transactional memories (TMs) is difficult because of the unbounded number, length, and delay of concurrent transactions, as well as the unbounded size of the memory. We show that, under certain conditions satisfied by most TMs we know of, the model checking problem can be reduced to a finite-state problem, and we illustrate the use of the method by proving the correctness of several TMs, including two-phase locking, DSTM, and TL2. The safety properties we consider include strict serializability and opacity; the liveness properties include obstruction freedom, livelock freedom, and wait freedom. Our main contribution lies in the structure of the proofs, which are largely automated and not restricted to the TMs mentioned above. In a first step we show that every TM that enjoys certain structural properties either violates a requirement on some program with two threads and two shared variables, or satisfies the requirement on all programs. In the second step, we use a model checker to prove the requirement for the TM applied to a most general program with two threads and two variables. In the safety case, the model checker checks language inclusion between two finite-state transition systems, a nondeterministic transition system representing the given TM applied to a most general program, and a deterministic transition system representing a most liberal safe TM applied to the same program. The given TM transition system is nondeterministic because a TM can be used with different contention managers, which resolve conflicts differently. In the liveness case, the model checker analyzes fairness conditions on the given TM transition system.","lang":"eng"}],"date_updated":"2021-01-12T07:43:14Z","_id":"3402","author":[{"full_name":"Guerraoui, Rachid","first_name":"Rachid","last_name":"Guerraoui"},{"full_name":"Thomas Henzinger","id":"40876CD8-F248-11E8-B48F-1D18A9856A87","last_name":"Henzinger","first_name":"Thomas A","orcid":"0000−0002−2985−7724"},{"full_name":"Vasu Singh","last_name":"Singh","id":"4DAE2708-F248-11E8-B48F-1D18A9856A87","first_name":"Vasu"}],"title":"Model checking transactional memories","publisher":"Springer","status":"public","month":"03","publication":"Distributed Computing","page":"129 - 145","date_created":"2018-12-11T12:03:08Z","doi":"10.1007/s00446-009-0092-6","publication_status":"published","date_published":"2010-03-01T00:00:00Z","type":"journal_article","pubrep_id":"74","publist_id":"3000","main_file_link":[{"url":"http://infoscience.epfl.ch/record/117513/files/PLDI_paper.pdf","open_access":"0"}],"intvolume":"        22","quality_controlled":0,"citation":{"ama":"Guerraoui R, Henzinger TA, Singh V. Model checking transactional memories. <i>Distributed Computing</i>. 2010;22(3):129-145. doi:<a href=\"https://doi.org/10.1007/s00446-009-0092-6\">10.1007/s00446-009-0092-6</a>","ieee":"R. Guerraoui, T. A. Henzinger, and V. Singh, “Model checking transactional memories,” <i>Distributed Computing</i>, vol. 22, no. 3. Springer, pp. 129–145, 2010.","short":"R. Guerraoui, T.A. Henzinger, V. Singh, Distributed Computing 22 (2010) 129–145.","chicago":"Guerraoui, Rachid, Thomas A Henzinger, and Vasu Singh. “Model Checking Transactional Memories.” <i>Distributed Computing</i>. Springer, 2010. <a href=\"https://doi.org/10.1007/s00446-009-0092-6\">https://doi.org/10.1007/s00446-009-0092-6</a>.","apa":"Guerraoui, R., Henzinger, T. A., &#38; Singh, V. (2010). Model checking transactional memories. <i>Distributed Computing</i>. Springer. <a href=\"https://doi.org/10.1007/s00446-009-0092-6\">https://doi.org/10.1007/s00446-009-0092-6</a>","ista":"Guerraoui R, Henzinger TA, Singh V. 2010. Model checking transactional memories. Distributed Computing. 22(3), 129–145.","mla":"Guerraoui, Rachid, et al. “Model Checking Transactional Memories.” <i>Distributed Computing</i>, vol. 22, no. 3, Springer, 2010, pp. 129–45, doi:<a href=\"https://doi.org/10.1007/s00446-009-0092-6\">10.1007/s00446-009-0092-6</a>."},"volume":22},{"extern":1,"year":"2010","day":"22","issue":"6","abstract":[{"lang":"eng","text":"Rate remapping is a conjunctive code that potentially enables hippocampal place cells to jointly represent spatial and nonspatial information. In this issue of Neuron, Rennó-Costa et al. introduce a theoretical model wherein the convergence of the medial and lateral entorhinal excitatory inputs, combined with local inhibition, explains hippocampal rate remapping. © 2010 Elsevier Inc."}],"date_updated":"2019-05-10T12:19:51Z","_id":"3403","author":[{"first_name":"Barty","last_name":"Pleydell Bouverie","full_name":"Pleydell-Bouverie, Barty"},{"full_name":"Jozsef Csicsvari","id":"3FA14672-F248-11E8-B48F-1D18A9856A87","last_name":"Csicsvari","orcid":"0000-0002-5193-4036","first_name":"Jozsef L"}],"title":"Rate remapping: When the code goes beyond space (preview)","status":"public","publisher":"Elsevier","month":"12","publication":"Neuron","page":"1015 - 1016","date_created":"2018-12-11T12:03:08Z","doi":"10.1016/j.neuron.2010.12.011","publication_status":"published","date_published":"2010-12-22T00:00:00Z","type":"review","publist_id":"2999","quality_controlled":0,"volume":68,"citation":{"short":"B. Pleydell Bouverie, J.L. Csicsvari, Neuron 68 (2010) 1015–1016.","ieee":"B. Pleydell Bouverie and J. L. Csicsvari, “Rate remapping: When the code goes beyond space (preview),” <i>Neuron</i>, vol. 68, no. 6. Elsevier, pp. 1015–1016, 2010.","ama":"Pleydell Bouverie B, Csicsvari JL. Rate remapping: When the code goes beyond space (preview). <i>Neuron</i>. 2010;68(6):1015-1016. doi:<a href=\"https://doi.org/10.1016/j.neuron.2010.12.011\">10.1016/j.neuron.2010.12.011</a>","chicago":"Pleydell Bouverie, Barty, and Jozsef L Csicsvari. “Rate Remapping: When the Code Goes beyond Space (Preview).” <i>Neuron</i>. Elsevier, 2010. <a href=\"https://doi.org/10.1016/j.neuron.2010.12.011\">https://doi.org/10.1016/j.neuron.2010.12.011</a>.","ista":"Pleydell Bouverie B, Csicsvari JL. 2010. Rate remapping: When the code goes beyond space (preview). Neuron. 68(6), 1015–1016.","apa":"Pleydell Bouverie, B., &#38; Csicsvari, J. L. (2010). Rate remapping: When the code goes beyond space (preview). <i>Neuron</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.neuron.2010.12.011\">https://doi.org/10.1016/j.neuron.2010.12.011</a>","mla":"Pleydell Bouverie, Barty, and Jozsef L. Csicsvari. “Rate Remapping: When the Code Goes beyond Space (Preview).” <i>Neuron</i>, vol. 68, no. 6, Elsevier, 2010, pp. 1015–16, doi:<a href=\"https://doi.org/10.1016/j.neuron.2010.12.011\">10.1016/j.neuron.2010.12.011</a>."},"intvolume":"        68"},{"month":"11","title":"Pharmacology of ionotropic glutamate receptors: a structural perspective","publisher":"Elsevier","status":"public","_id":"3406","author":[{"full_name":"Stawski, Philipp","first_name":"Philipp","last_name":"Stawski"},{"id":"33BA6C30-F248-11E8-B48F-1D18A9856A87","last_name":"Janovjak","first_name":"Harald L","orcid":"0000-0002-8023-9315","full_name":"Harald Janovjak"},{"full_name":"Trauner, Dirk","last_name":"Trauner","first_name":"Dirk"}],"day":"15","year":"2010","extern":1,"date_updated":"2019-04-26T07:22:27Z","abstract":[{"text":"The impact of structural biology on the design of ligands (agonists, antagonists and modulators) for ionotropic glutamate receptors is reviewed.","lang":"eng"}],"issue":"22","quality_controlled":0,"intvolume":"        18","volume":18,"citation":{"chicago":"Stawski, Philipp, Harald L Janovjak, and Dirk Trauner. “Pharmacology of Ionotropic Glutamate Receptors: A Structural Perspective.” <i>Bioorganic and Medicinal Chemistry</i>. Elsevier, 2010. <a href=\"https://doi.org/10.1016/j.bmc.2010.09.012\">https://doi.org/10.1016/j.bmc.2010.09.012</a>.","mla":"Stawski, Philipp, et al. “Pharmacology of Ionotropic Glutamate Receptors: A Structural Perspective.” <i>Bioorganic and Medicinal Chemistry</i>, vol. 18, no. 22, Elsevier, 2010, pp. 7759–72, doi:<a href=\"https://doi.org/10.1016/j.bmc.2010.09.012\">10.1016/j.bmc.2010.09.012</a>.","apa":"Stawski, P., Janovjak, H. L., &#38; Trauner, D. (2010). Pharmacology of ionotropic glutamate receptors: a structural perspective. <i>Bioorganic and Medicinal Chemistry</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.bmc.2010.09.012\">https://doi.org/10.1016/j.bmc.2010.09.012</a>","ista":"Stawski P, Janovjak HL, Trauner D. 2010. Pharmacology of ionotropic glutamate receptors: a structural perspective. Bioorganic and Medicinal Chemistry. 18(22), 7759–7772.","short":"P. Stawski, H.L. Janovjak, D. Trauner, Bioorganic and Medicinal Chemistry 18 (2010) 7759–7772.","ieee":"P. Stawski, H. L. Janovjak, and D. Trauner, “Pharmacology of ionotropic glutamate receptors: a structural perspective,” <i>Bioorganic and Medicinal Chemistry</i>, vol. 18, no. 22. Elsevier, pp. 7759–7772, 2010.","ama":"Stawski P, Janovjak HL, Trauner D. Pharmacology of ionotropic glutamate receptors: a structural perspective. <i>Bioorganic and Medicinal Chemistry</i>. 2010;18(22):7759-7772. doi:<a href=\"https://doi.org/10.1016/j.bmc.2010.09.012\">10.1016/j.bmc.2010.09.012</a>"},"publist_id":"2996","date_published":"2010-11-15T00:00:00Z","type":"review","date_created":"2018-12-11T12:03:10Z","page":"7759 - 7772","publication":"Bioorganic and Medicinal Chemistry","publication_status":"published","doi":"10.1016/j.bmc.2010.09.012"},{"title":"A light-gated, potassium-selective glutamate receptor for the optical inhibition of neuronal firing","publisher":"Nature Publishing Group","status":"public","month":"06","extern":1,"year":"2010","day":"27","abstract":[{"text":"Genetically targeted light-activated ion channels and pumps make it possible to determine the role of specific neurons in neuronal circuits, information processing and behavior. We developed a K+-selective ionotropic glutamate receptor that reversibly inhibits neuronal activity in response to light in dissociated neurons and brain slice and also reversibly suppresses behavior in zebrafish. The receptor is a chimera of the pore region of a K+-selective bacterial glutamate receptor and the ligand-binding domain of a light-gated mammalian kainate receptor. This hyperpolarizing light-gated channel, HyLighter, is turned on by a brief light pulse at one wavelength and turned off by a pulse at a second wavelength. The control is obtained at moderate intensity. After optical activation, the photocurrent and optical silencing of activity persists in the dark for extended periods. The low light requirement and bi-stability of HyLighter represent advantages for the dissection of neural circuitry.","lang":"eng"}],"date_updated":"2021-01-12T07:43:16Z","_id":"3407","author":[{"orcid":"0000-0002-8023-9315","first_name":"Harald L","last_name":"Janovjak","id":"33BA6C30-F248-11E8-B48F-1D18A9856A87","full_name":"Harald Janovjak"},{"last_name":"Szobota","first_name":"Stephanie","full_name":"Szobota, Stephanie"},{"full_name":"Wyart, Claire","last_name":"Wyart","first_name":"Claire"},{"full_name":"Trauner, Dirk","last_name":"Trauner","first_name":"Dirk"},{"full_name":"Isacoff, Ehud Y","first_name":"Ehud","last_name":"Isacoff"}],"publist_id":"2995","intvolume":"        13","volume":13,"quality_controlled":0,"citation":{"chicago":"Janovjak, Harald L, Stephanie Szobota, Claire Wyart, Dirk Trauner, and Ehud Isacoff. “A Light-Gated, Potassium-Selective Glutamate Receptor for the Optical Inhibition of Neuronal Firing.” <i>Nature Neuroscience</i>. Nature Publishing Group, 2010. <a href=\"https://doi.org/10.1038/nn.2589\">https://doi.org/10.1038/nn.2589</a>.","mla":"Janovjak, Harald L., et al. “A Light-Gated, Potassium-Selective Glutamate Receptor for the Optical Inhibition of Neuronal Firing.” <i>Nature Neuroscience</i>, vol. 13, Nature Publishing Group, 2010, pp. 1027–32, doi:<a href=\"https://doi.org/10.1038/nn.2589\">10.1038/nn.2589</a>.","ista":"Janovjak HL, Szobota S, Wyart C, Trauner D, Isacoff E. 2010. A light-gated, potassium-selective glutamate receptor for the optical inhibition of neuronal firing. Nature Neuroscience. 13, 1027–1032.","apa":"Janovjak, H. L., Szobota, S., Wyart, C., Trauner, D., &#38; Isacoff, E. (2010). A light-gated, potassium-selective glutamate receptor for the optical inhibition of neuronal firing. <i>Nature Neuroscience</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/nn.2589\">https://doi.org/10.1038/nn.2589</a>","ieee":"H. L. Janovjak, S. Szobota, C. Wyart, D. Trauner, and E. Isacoff, “A light-gated, potassium-selective glutamate receptor for the optical inhibition of neuronal firing,” <i>Nature Neuroscience</i>, vol. 13. Nature Publishing Group, pp. 1027–1032, 2010.","ama":"Janovjak HL, Szobota S, Wyart C, Trauner D, Isacoff E. A light-gated, potassium-selective glutamate receptor for the optical inhibition of neuronal firing. <i>Nature Neuroscience</i>. 2010;13:1027-1032. doi:<a href=\"https://doi.org/10.1038/nn.2589\">10.1038/nn.2589</a>","short":"H.L. Janovjak, S. Szobota, C. Wyart, D. Trauner, E. Isacoff, Nature Neuroscience 13 (2010) 1027–1032."},"publication":"Nature Neuroscience","page":"1027 - 1032","date_created":"2018-12-11T12:03:10Z","doi":"10.1038/nn.2589","publication_status":"published","date_published":"2010-06-27T00:00:00Z","type":"journal_article"},{"quality_controlled":0,"citation":{"chicago":"Tkačik, Gašper. “Lecture Notes for 2010 Summer School on Quantitative Evolutionary and Comparative Genomics.” Elsevier, 2010.","mla":"Tkačik, Gašper. <i>Lecture Notes for 2010 Summer School on Quantitative Evolutionary and Comparative Genomics</i>. Elsevier, 2010.","apa":"Tkačik, G. (2010). Lecture notes for 2010 summer school on Quantitative Evolutionary and Comparative Genomics. Presented at the Summer School on Quantitative Evolutionary and Comparative Genomics, Elsevier.","ista":"Tkačik G. 2010. Lecture notes for 2010 summer school on Quantitative Evolutionary and Comparative Genomics. Summer School on Quantitative Evolutionary and Comparative Genomics.","ama":"Tkačik G. Lecture notes for 2010 summer school on Quantitative Evolutionary and Comparative Genomics. In: Elsevier; 2010.","ieee":"G. Tkačik, “Lecture notes for 2010 summer school on Quantitative Evolutionary and Comparative Genomics,” presented at the Summer School on Quantitative Evolutionary and Comparative Genomics, 2010.","short":"G. Tkačik, in:, Elsevier, 2010."},"publist_id":"2970","main_file_link":[{"open_access":"1","url":"http://arxiv.org/pdf/1006.4291"}],"date_published":"2010-06-22T00:00:00Z","type":"conference","date_created":"2018-12-11T12:03:17Z","publication_status":"published","conference":{"name":"Summer School on Quantitative Evolutionary and Comparative Genomics"},"month":"06","title":"Lecture notes for 2010 summer school on Quantitative Evolutionary and Comparative Genomics","oa":1,"status":"public","publisher":"Elsevier","_id":"3430","author":[{"orcid":"0000-0002-6699-1455","first_name":"Gasper","id":"3D494DCA-F248-11E8-B48F-1D18A9856A87","last_name":"Tkacik","full_name":"Gasper Tkacik"}],"day":"22","extern":1,"year":"2010","date_updated":"2021-01-12T07:43:25Z","abstract":[{"lang":"eng","text":"These are notes for a set of 7 two-hour lectures given at the 2010 Summer School on Quantitative Evolutionary and Comparative Genomics at OIST, Okinawa, Japan. The emphasis is on understanding how biological systems process information. We take a physicist's approach of looking for simple phenomenological descriptions that can address the questions of biological function without necessarily modeling all (mostly unknown) microscopic details; the example that is developed throughout the notes is transcriptional regulation in genetic regulatory networks. We present tools from information theory and statistical physics that can be used to analyze noisy nonlinear biological networks, and build generative and predictive models of regulatory processes."}]},{"type":"journal_article","date_published":"2010-08-01T00:00:00Z","doi":"10.1038/nn.2599","publication_status":"published","publication":"Nature Neuroscience","page":"995 - 1002","date_created":"2018-12-11T12:03:21Z","volume":13,"quality_controlled":0,"intvolume":"        13","citation":{"short":"D. Dupret, J. O’Neill, B. Pleydell Bouverie, J.L. Csicsvari, Nature Neuroscience 13 (2010) 995–1002.","ama":"Dupret D, O’Neill J, Pleydell Bouverie B, Csicsvari JL. The reorganization and reactivation of hippocampal maps predict spatial memory performance. <i>Nature Neuroscience</i>. 2010;13(8):995-1002. doi:<a href=\"https://doi.org/10.1038/nn.2599\">10.1038/nn.2599</a>","ieee":"D. Dupret, J. O’Neill, B. Pleydell Bouverie, and J. L. Csicsvari, “The reorganization and reactivation of hippocampal maps predict spatial memory performance,” <i>Nature Neuroscience</i>, vol. 13, no. 8. Nature Publishing Group, pp. 995–1002, 2010.","mla":"Dupret, David, et al. “The Reorganization and Reactivation of Hippocampal Maps Predict Spatial Memory Performance.” <i>Nature Neuroscience</i>, vol. 13, no. 8, Nature Publishing Group, 2010, pp. 995–1002, doi:<a href=\"https://doi.org/10.1038/nn.2599\">10.1038/nn.2599</a>.","apa":"Dupret, D., O’Neill, J., Pleydell Bouverie, B., &#38; Csicsvari, J. L. (2010). The reorganization and reactivation of hippocampal maps predict spatial memory performance. <i>Nature Neuroscience</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/nn.2599\">https://doi.org/10.1038/nn.2599</a>","ista":"Dupret D, O’Neill J, Pleydell Bouverie B, Csicsvari JL. 2010. The reorganization and reactivation of hippocampal maps predict spatial memory performance. Nature Neuroscience. 13(8), 995–1002.","chicago":"Dupret, David, Joseph O’Neill, Barty Pleydell Bouverie, and Jozsef L Csicsvari. “The Reorganization and Reactivation of Hippocampal Maps Predict Spatial Memory Performance.” <i>Nature Neuroscience</i>. Nature Publishing Group, 2010. <a href=\"https://doi.org/10.1038/nn.2599\">https://doi.org/10.1038/nn.2599</a>."},"publist_id":"2946","author":[{"full_name":"Dupret, David","first_name":"David","last_name":"Dupret"},{"full_name":"Joseph O'Neill","last_name":"O'Neill","id":"426376DC-F248-11E8-B48F-1D18A9856A87","first_name":"Joseph"},{"last_name":"Pleydell Bouverie","first_name":"Barty","full_name":"Pleydell-Bouverie, Barty"},{"full_name":"Jozsef Csicsvari","first_name":"Jozsef L","orcid":"0000-0002-5193-4036","last_name":"Csicsvari","id":"3FA14672-F248-11E8-B48F-1D18A9856A87"}],"_id":"3441","issue":"8","acknowledgement":"Discussed in the News and Views section of the journal by Jeffery and Cacucci\n","abstract":[{"lang":"eng","text":"The hippocampus is an important brain circuit for spatial memory and the spatially selective spiking of hippocampal neuronal assemblies is thought to provide a mnemonic representation of space. We found that remembering newly learnt goal locations required NMDA receptorĝ€&quot;dependent stabilization and enhanced reactivation of goal-related hippocampal assemblies. During spatial learning, place-related firing patterns in the CA1, but not CA3, region of the rat hippocampus were reorganized to represent new goal locations. Such reorganization did not occur when goals were marked by visual cues. The stabilization and successful retrieval of these newly acquired CA1 representations of behaviorally relevant places was NMDAR dependent and necessary for subsequent memory retention performance. Goal-related assembly patterns associated with sharp wave/ripple network oscillations, during both learning and subsequent rest periods, predicted memory performance. Together, these results suggest that the reorganization and reactivation of assembly firing patterns in the hippocampus represent the formation and expression of new spatial memory traces. © 2010 Nature America, Inc. All rights reserved."}],"date_updated":"2021-01-12T07:43:29Z","extern":1,"year":"2010","day":"01","month":"08","publisher":"Nature Publishing Group","status":"public","title":"The reorganization and reactivation of hippocampal maps predict spatial memory performance"},{"publist_id":"2945","citation":{"chicago":"O’Neill, Joseph, Barty Pleydell Bouverie, David Dupret, and Jozsef L Csicsvari. “Play It Again: Reactivation of Waking Experience and Memory.” <i>Trends in Neurosciences</i>. Elsevier, 2010. <a href=\"https://doi.org/10.1016/j.tins.2010.01.006\">https://doi.org/10.1016/j.tins.2010.01.006</a>.","apa":"O’Neill, J., Pleydell Bouverie, B., Dupret, D., &#38; Csicsvari, J. L. (2010). Play it again: reactivation of waking experience and memory. <i>Trends in Neurosciences</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.tins.2010.01.006\">https://doi.org/10.1016/j.tins.2010.01.006</a>","ista":"O’Neill J, Pleydell Bouverie B, Dupret D, Csicsvari JL. 2010. Play it again: reactivation of waking experience and memory. Trends in Neurosciences. 33(5), 220–229.","mla":"O’Neill, Joseph, et al. “Play It Again: Reactivation of Waking Experience and Memory.” <i>Trends in Neurosciences</i>, vol. 33, no. 5, Elsevier, 2010, pp. 220–29, doi:<a href=\"https://doi.org/10.1016/j.tins.2010.01.006\">10.1016/j.tins.2010.01.006</a>.","ama":"O’Neill J, Pleydell Bouverie B, Dupret D, Csicsvari JL. Play it again: reactivation of waking experience and memory. <i>Trends in Neurosciences</i>. 2010;33(5):220-229. doi:<a href=\"https://doi.org/10.1016/j.tins.2010.01.006\">10.1016/j.tins.2010.01.006</a>","ieee":"J. O’Neill, B. Pleydell Bouverie, D. Dupret, and J. L. Csicsvari, “Play it again: reactivation of waking experience and memory,” <i>Trends in Neurosciences</i>, vol. 33, no. 5. Elsevier, pp. 220–229, 2010.","short":"J. O’Neill, B. Pleydell Bouverie, D. Dupret, J.L. Csicsvari, Trends in Neurosciences 33 (2010) 220–229."},"intvolume":"        33","volume":33,"quality_controlled":0,"page":"220 - 229","date_created":"2018-12-11T12:03:21Z","publication":"Trends in Neurosciences","publication_status":"published","doi":"10.1016/j.tins.2010.01.006","date_published":"2010-05-01T00:00:00Z","type":"journal_article","title":"Play it again: reactivation of waking experience and memory","publisher":"Elsevier","status":"public","month":"05","day":"01","extern":1,"year":"2010","date_updated":"2021-01-12T07:43:29Z","issue":"5","abstract":[{"lang":"eng","text":"Episodic and spatial memories each involve the encoding of complex associations in hippocampal neuronal circuits. Such memory traces could be stabilised from short- to long-term forms by consolidation processes involving the 'reactivation' of the original network firing patterns during sleep and rest. Waking experience can be replayed in many different brain areas, but an important role for the hippocampus lies in the organisation of the 'reactivation' process. Emerging evidence suggests that sharp wave/ripple (SWR) events in the hippocampus could coordinate the reactivation of memory traces and direct their reinstatement in cortical circuits. Although the mechanisms remain uncertain, there is a growing consensus that such SWR-directed reactivation of brain-wide memory traces could underlie memory consolidation. © 2010 Elsevier Ltd."}],"_id":"3442","author":[{"first_name":"Joseph","last_name":"O'Neill","id":"426376DC-F248-11E8-B48F-1D18A9856A87","full_name":"Joseph O'Neill"},{"last_name":"Pleydell Bouverie","first_name":"Barty","full_name":"Pleydell-Bouverie, Barty"},{"first_name":"David","last_name":"Dupret","full_name":"Dupret, David"},{"full_name":"Jozsef Csicsvari","orcid":"0000-0002-5193-4036","first_name":"Jozsef L","id":"3FA14672-F248-11E8-B48F-1D18A9856A87","last_name":"Csicsvari"}]},{"title":"Grundlagen zellulärer Erregbarkeit","status":"public","publisher":"Springer","month":"01","day":"01","year":"2010","extern":1,"date_updated":"2021-01-12T07:43:35Z","_id":"3459","author":[{"last_name":"Fakler","first_name":"Bernd","full_name":"Fakler, Bernd"},{"last_name":"Jonas","id":"353C1B58-F248-11E8-B48F-1D18A9856A87","first_name":"Peter M","orcid":"0000-0001-5001-4804","full_name":"Peter Jonas"}],"publist_id":"2928","quality_controlled":0,"editor":[{"last_name":"Schmidt","first_name":"R.","full_name":"Schmidt, R. F."},{"full_name":"Heckmann, M.","last_name":"Heckmann","first_name":"M."},{"first_name":"Florian","last_name":"Lang","full_name":"Lang, Florian"}],"citation":{"short":"B. Fakler, P.M. Jonas, in:, R. Schmidt, M. Heckmann, F. Lang (Eds.), Physiologie Des Menschen, Springer, 2010.","ama":"Fakler B, Jonas PM. Grundlagen zellulärer Erregbarkeit. In: Schmidt R, Heckmann M, Lang F, eds. <i>Physiologie Des Menschen</i>. Springer; 2010.","ieee":"B. Fakler and P. M. Jonas, “Grundlagen zellulärer Erregbarkeit,” in <i>Physiologie Des Menschen</i>, R. Schmidt, M. Heckmann, and F. Lang, Eds. Springer, 2010.","ista":"Fakler B, Jonas PM. 2010.Grundlagen zellulärer Erregbarkeit. In: Physiologie Des Menschen. .","apa":"Fakler, B., &#38; Jonas, P. M. (2010). Grundlagen zellulärer Erregbarkeit. In R. Schmidt, M. Heckmann, &#38; F. Lang (Eds.), <i>Physiologie Des Menschen</i>. Springer.","mla":"Fakler, Bernd, and Peter M. Jonas. “Grundlagen Zellulärer Erregbarkeit.” <i>Physiologie Des Menschen</i>, edited by R. Schmidt et al., Springer, 2010.","chicago":"Fakler, Bernd, and Peter M Jonas. “Grundlagen Zellulärer Erregbarkeit.” In <i>Physiologie Des Menschen</i>, edited by R. Schmidt, M. Heckmann, and Florian Lang. Springer, 2010."},"date_created":"2018-12-11T12:03:26Z","publication":"Physiologie Des Menschen","publication_status":"published","date_published":"2010-01-01T00:00:00Z","type":"book_chapter"},{"doi":"10.1007/s00167-010-1227-9","publication_status":"published","publication":"Knee Surgery, Sports Traumatology, Arthroscopy","date_created":"2018-12-11T12:03:39Z","page":"1792 - 1794","type":"journal_article","oa_version":"None","date_published":"2010-08-20T00:00:00Z","language":[{"iso":"eng"}],"publist_id":"2889","scopus_import":1,"quality_controlled":"1","volume":18,"citation":{"chicago":"Sabeti Aschraf, M., C. Gonano, E. Nemecek, Lisa Cichocki, and C. Schueller Weidekamm. “Intra-Operative Ultrasound Facilitates the Localization of the Calcific Deposit during Arthroscopic Treatment of Calcifying Tendinitis.” <i>Knee Surgery, Sports Traumatology, Arthroscopy</i>. Springer, 2010. <a href=\"https://doi.org/10.1007/s00167-010-1227-9\">https://doi.org/10.1007/s00167-010-1227-9</a>.","mla":"Sabeti Aschraf, M., et al. “Intra-Operative Ultrasound Facilitates the Localization of the Calcific Deposit during Arthroscopic Treatment of Calcifying Tendinitis.” <i>Knee Surgery, Sports Traumatology, Arthroscopy</i>, vol. 18, no. 12, Springer, 2010, pp. 1792–94, doi:<a href=\"https://doi.org/10.1007/s00167-010-1227-9\">10.1007/s00167-010-1227-9</a>.","ista":"Sabeti Aschraf M, Gonano C, Nemecek E, Cichocki L, Schueller Weidekamm C. 2010. Intra-operative ultrasound facilitates the localization of the calcific deposit during arthroscopic treatment of calcifying tendinitis. Knee Surgery, Sports Traumatology, Arthroscopy. 18(12), 1792–1794.","apa":"Sabeti Aschraf, M., Gonano, C., Nemecek, E., Cichocki, L., &#38; Schueller Weidekamm, C. (2010). Intra-operative ultrasound facilitates the localization of the calcific deposit during arthroscopic treatment of calcifying tendinitis. <i>Knee Surgery, Sports Traumatology, Arthroscopy</i>. Springer. <a href=\"https://doi.org/10.1007/s00167-010-1227-9\">https://doi.org/10.1007/s00167-010-1227-9</a>","ieee":"M. Sabeti Aschraf, C. Gonano, E. Nemecek, L. Cichocki, and C. Schueller Weidekamm, “Intra-operative ultrasound facilitates the localization of the calcific deposit during arthroscopic treatment of calcifying tendinitis,” <i>Knee Surgery, Sports Traumatology, Arthroscopy</i>, vol. 18, no. 12. Springer, pp. 1792–1794, 2010.","ama":"Sabeti Aschraf M, Gonano C, Nemecek E, Cichocki L, Schueller Weidekamm C. Intra-operative ultrasound facilitates the localization of the calcific deposit during arthroscopic treatment of calcifying tendinitis. <i>Knee Surgery, Sports Traumatology, Arthroscopy</i>. 2010;18(12):1792-1794. doi:<a href=\"https://doi.org/10.1007/s00167-010-1227-9\">10.1007/s00167-010-1227-9</a>","short":"M. Sabeti Aschraf, C. Gonano, E. Nemecek, L. Cichocki, C. Schueller Weidekamm, Knee Surgery, Sports Traumatology, Arthroscopy 18 (2010) 1792–1794."},"intvolume":"        18","abstract":[{"text":"Purpose\r\nCalcifying tendinitis is a common condition of the shoulder. In many cases, arthroscopic reduction in the deposit is indicated. The localization of the deposit is sometimes challenging and time-consuming. Pre-operative ultrasound (US)-guided needle placement in the deposit and pre-operative US marking of the deposit at the skin with a ballpoint are described and recommended methods to alleviate the procedure without using ionizing radiation by fluoroscopy.\r\nMethods\r\nIntra-operative sonography of the shoulder is introduced as a new method to localize the calcific deposit with high accuracy. After standard arthroscopic buresectomy, the surgeon performs an ultrasound examination under sterile conditions to localize the deposits. A ventral longitudinal US section is recommended, and the upper arm is rotated until the deposit is visible. Subsequently, perpendicular to the skin at the position of the transducer, a needle is introduced under arthroscopic and ultrasound visualization to puncture the deposit.\r\nResults\r\nThe presence of snow-white crystals at the tip of the needle proves the exact localization. Consecutively, the curettage can be accomplished. Another intra-operative sonography evaluates possible calcific remnants and the tendon structure.\r\nConclusion\r\nThis new technique may alleviate arthroscopic calcific deposit curettage by visualizing the deposit without using ionizing radiation. Additionally, soft tissue damage due to decreased number of punctures to detect the deposit may be achieved. Both factors may contribute to reduced operation time.","lang":"eng"}],"issue":"12","date_updated":"2021-01-12T07:43:51Z","year":"2010","day":"20","author":[{"first_name":"M.","last_name":"Sabeti Aschraf","full_name":"Sabeti Aschraf, M."},{"first_name":"C.","last_name":"Gonano","full_name":"Gonano, C."},{"full_name":"Nemecek, E.","last_name":"Nemecek","first_name":"E."},{"full_name":"Cichocki, Lisa","first_name":"Lisa","id":"3BC78B60-F248-11E8-B48F-1D18A9856A87","last_name":"Cichocki"},{"first_name":"C.","last_name":"Schueller Weidekamm","full_name":"Schueller Weidekamm, C."}],"_id":"3498","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","publisher":"Springer","status":"public","title":"Intra-operative ultrasound facilitates the localization of the calcific deposit during arthroscopic treatment of calcifying tendinitis","month":"08"},{"month":"04","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"Society for Neuroscience","status":"public","oa":1,"title":"High-frequency network activity, global increase in neuronal activity, and synchrony expansion precede epileptic seizures in vitro","author":[{"last_name":"Jiruska","first_name":"Premysl","full_name":"Jiruska, Premysl"},{"full_name":"Csicsvari, Jozsef L","orcid":"0000-0002-5193-4036","first_name":"Jozsef L","id":"3FA14672-F248-11E8-B48F-1D18A9856A87","last_name":"Csicsvari"},{"first_name":"Andrew","last_name":"Powell","full_name":"Powell, Andrew"},{"last_name":"Fox","first_name":"John","full_name":"Fox, John"},{"last_name":"Chang","first_name":"Wei","full_name":"Chang, Wei"},{"full_name":"Vreugdenhil, Martin","last_name":"Vreugdenhil","first_name":"Martin"},{"full_name":"Li, Xiaoli","first_name":"Xiaoli","last_name":"Li"},{"last_name":"Palus","first_name":"Milan","full_name":"Palus, Milan"},{"full_name":"Bujan, Alejandro","last_name":"Bujan","first_name":"Alejandro"},{"full_name":"Dearden, Richard","first_name":"Richard","last_name":"Dearden"},{"full_name":"Jefferys, John","first_name":"John","last_name":"Jefferys"}],"_id":"3538","issue":"16","abstract":[{"text":"How seizures start is a major question in epilepsy research. Preictal EEG changes occur in both human patients and animal models, but their underlying mechanisms and relationship with seizure initiation remain unknown. Here we demonstrate the existence, in the hippocampal CA1 region, of a preictal state characterized by the progressive and global increase in neuronal activity associated with a widespread buildup of low-amplitude high-frequency activity (HFA) (&gt; 100 Hz) and reduction in system complexity. HFA is generated by the firing of neurons, mainly pyramidal cells, at much lower frequencies. Individual cycles of HFA are generated by the near-synchronous (within similar to 5 ms) firing of small numbers of pyramidal cells. The presence of HFA in the low-calcium model implicates nonsynaptic synchronization; the presence of very similar HFA in the high-potassium model shows that it does not depend on an absence of synaptic transmission. Immediately before seizure onset, CA1 is in a state of high sensitivity in which weak depolarizing or synchronizing perturbations can trigger seizures. Transition to seizure is characterized by a rapid expansion and fusion of the neuronal populations responsible for HFA, associated with a progressive slowing of HFA, leading to a single, massive, hypersynchronous cluster generating the high-amplitude low-frequency activity of the seizure.","lang":"eng"}],"date_updated":"2021-01-12T07:44:10Z","extern":"1","year":"2010","day":"21","quality_controlled":"1","intvolume":"        30","volume":30,"citation":{"apa":"Jiruska, P., Csicsvari, J. L., Powell, A., Fox, J., Chang, W., Vreugdenhil, M., … Jefferys, J. (2010). High-frequency network activity, global increase in neuronal activity, and synchrony expansion precede epileptic seizures in vitro. <i>Journal of Neuroscience</i>. Society for Neuroscience. <a href=\"https://doi.org/10.1523/JNEUROSCI.0535-10.2010\">https://doi.org/10.1523/JNEUROSCI.0535-10.2010</a>","ista":"Jiruska P, Csicsvari JL, Powell A, Fox J, Chang W, Vreugdenhil M, Li X, Palus M, Bujan A, Dearden R, Jefferys J. 2010. High-frequency network activity, global increase in neuronal activity, and synchrony expansion precede epileptic seizures in vitro. Journal of Neuroscience. 30(16), 5690–5701.","mla":"Jiruska, Premysl, et al. “High-Frequency Network Activity, Global Increase in Neuronal Activity, and Synchrony Expansion Precede Epileptic Seizures in Vitro.” <i>Journal of Neuroscience</i>, vol. 30, no. 16, Society for Neuroscience, 2010, pp. 5690–701, doi:<a href=\"https://doi.org/10.1523/JNEUROSCI.0535-10.2010\">10.1523/JNEUROSCI.0535-10.2010</a>.","chicago":"Jiruska, Premysl, Jozsef L Csicsvari, Andrew Powell, John Fox, Wei Chang, Martin Vreugdenhil, Xiaoli Li, et al. “High-Frequency Network Activity, Global Increase in Neuronal Activity, and Synchrony Expansion Precede Epileptic Seizures in Vitro.” <i>Journal of Neuroscience</i>. Society for Neuroscience, 2010. <a href=\"https://doi.org/10.1523/JNEUROSCI.0535-10.2010\">https://doi.org/10.1523/JNEUROSCI.0535-10.2010</a>.","short":"P. Jiruska, J.L. Csicsvari, A. Powell, J. Fox, W. Chang, M. Vreugdenhil, X. Li, M. Palus, A. Bujan, R. Dearden, J. Jefferys, Journal of Neuroscience 30 (2010) 5690–5701.","ieee":"P. Jiruska <i>et al.</i>, “High-frequency network activity, global increase in neuronal activity, and synchrony expansion precede epileptic seizures in vitro,” <i>Journal of Neuroscience</i>, vol. 30, no. 16. Society for Neuroscience, pp. 5690–5701, 2010.","ama":"Jiruska P, Csicsvari JL, Powell A, et al. High-frequency network activity, global increase in neuronal activity, and synchrony expansion precede epileptic seizures in vitro. <i>Journal of Neuroscience</i>. 2010;30(16):5690-5701. doi:<a href=\"https://doi.org/10.1523/JNEUROSCI.0535-10.2010\">10.1523/JNEUROSCI.0535-10.2010</a>"},"publist_id":"2848","main_file_link":[{"url":"http://www.jneurosci.org/content/30/16/5690","open_access":"1"}],"type":"journal_article","oa_version":"None","date_published":"2010-04-21T00:00:00Z","language":[{"iso":"eng"}],"doi":"10.1523/JNEUROSCI.0535-10.2010","publication_status":"published","publication":"Journal of Neuroscience","date_created":"2018-12-11T12:03:51Z","page":"5690 - 5701"},{"_id":"3592","author":[{"full_name":"Carvalho, Lara","first_name":"Lara","last_name":"Carvalho"},{"orcid":"0000-0002-0912-4566","first_name":"Carl-Philipp J","id":"39427864-F248-11E8-B48F-1D18A9856A87","last_name":"Heisenberg","full_name":"Heisenberg, Carl-Philipp J"}],"year":"2010","extern":"1","day":"01","issue":"Part 5","abstract":[{"text":"The zebrafish is a favorite model organism to study tissue morphogenesis during development at a subcellular level. This largely results from the fact that zebrafish embryos are transparent and thus accessible to various imaging techniques, such as confocal and two-photon excitation (2PE) microscopy. In particular, 2PE microscopy has been shown to be useful for imaging deep cell layers within the embryo and following tissue morphogenesis over long periods. This chapter describes how to use 2PE microscopy to study morphogenetic movements during early zebrafish embryonic development, providing a general blueprint for its use in zebrafish.","lang":"eng"}],"date_updated":"2021-01-12T07:44:31Z","month":"01","title":"Imaging zebrafish embryos by two-photon excitation time-lapse microscopy","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"Springer","status":"public","date_published":"2010-01-01T00:00:00Z","language":[{"iso":"eng"}],"oa_version":"None","type":"journal_article","publication":"Methods in Molecular Biology","page":"273 - 287","date_created":"2018-12-11T12:04:08Z","doi":"10.1007/978-1-60327-977-2_17","publication_status":"published","intvolume":"       546","citation":{"short":"L. Carvalho, C.-P.J. Heisenberg, Methods in Molecular Biology 546 (2010) 273–287.","ieee":"L. Carvalho and C.-P. J. Heisenberg, “Imaging zebrafish embryos by two-photon excitation time-lapse microscopy,” <i>Methods in Molecular Biology</i>, vol. 546, no. Part 5. Springer, pp. 273–287, 2010.","ama":"Carvalho L, Heisenberg C-PJ. Imaging zebrafish embryos by two-photon excitation time-lapse microscopy. <i>Methods in Molecular Biology</i>. 2010;546(Part 5):273-287. doi:<a href=\"https://doi.org/10.1007/978-1-60327-977-2_17\">10.1007/978-1-60327-977-2_17</a>","chicago":"Carvalho, Lara, and Carl-Philipp J Heisenberg. “Imaging Zebrafish Embryos by Two-Photon Excitation Time-Lapse Microscopy.” <i>Methods in Molecular Biology</i>. Springer, 2010. <a href=\"https://doi.org/10.1007/978-1-60327-977-2_17\">https://doi.org/10.1007/978-1-60327-977-2_17</a>.","mla":"Carvalho, Lara, and Carl-Philipp J. Heisenberg. “Imaging Zebrafish Embryos by Two-Photon Excitation Time-Lapse Microscopy.” <i>Methods in Molecular Biology</i>, vol. 546, no. Part 5, Springer, 2010, pp. 273–87, doi:<a href=\"https://doi.org/10.1007/978-1-60327-977-2_17\">10.1007/978-1-60327-977-2_17</a>.","apa":"Carvalho, L., &#38; Heisenberg, C.-P. J. (2010). Imaging zebrafish embryos by two-photon excitation time-lapse microscopy. <i>Methods in Molecular Biology</i>. Springer. <a href=\"https://doi.org/10.1007/978-1-60327-977-2_17\">https://doi.org/10.1007/978-1-60327-977-2_17</a>","ista":"Carvalho L, Heisenberg C-PJ. 2010. Imaging zebrafish embryos by two-photon excitation time-lapse microscopy. Methods in Molecular Biology. 546(Part 5), 273–287."},"volume":546,"article_processing_charge":"No","publist_id":"2791"}]