[{"abstract":[{"lang":"eng","text":"We present a general parallel-repetition theorem with an efficient reduction. As a corollary of this theorem we establish that parallel repetition reduces the soundness error at an exponential rate in any public-coin argument, and more generally, any argument where the verifier's messages, but not necessarily its decision to accept or reject, can be efficiently simulated with noticeable probability."}],"publist_id":"3446","day":"26","extern":1,"alternative_title":["LNCS"],"status":"public","type":"conference","intvolume":"      5978","date_created":"2018-12-11T12:02:10Z","date_updated":"2021-01-12T07:41:59Z","publisher":"Springer","author":[{"last_name":"Håstad","full_name":"Håstad, Johan","first_name":"Johan"},{"full_name":"Pass, Rafael","first_name":"Rafael","last_name":"Pass"},{"last_name":"Wikström","first_name":"Douglas","full_name":"Wikström, Douglas"},{"last_name":"Pietrzak","orcid":"0000-0002-9139-1654","id":"3E04A7AA-F248-11E8-B48F-1D18A9856A87","first_name":"Krzysztof Z","full_name":"Krzysztof Pietrzak"}],"quality_controlled":0,"date_published":"2010-03-26T00:00:00Z","title":"An efficient parallel repetition theorem","_id":"3233","volume":5978,"publication_status":"published","year":"2010","doi":"10.1007/978-3-642-11799-2_1","conference":{"name":"TCC: Theory of Cryptography Conference"},"citation":{"chicago":"Håstad, Johan, Rafael Pass, Douglas Wikström, and Krzysztof Z Pietrzak. “An Efficient Parallel Repetition Theorem,” 5978:1–18. Springer, 2010. <a href=\"https://doi.org/10.1007/978-3-642-11799-2_1\">https://doi.org/10.1007/978-3-642-11799-2_1</a>.","ama":"Håstad J, Pass R, Wikström D, Pietrzak KZ. An efficient parallel repetition theorem. In: Vol 5978. Springer; 2010:1-18. doi:<a href=\"https://doi.org/10.1007/978-3-642-11799-2_1\">10.1007/978-3-642-11799-2_1</a>","ieee":"J. Håstad, R. Pass, D. Wikström, and K. Z. Pietrzak, “An efficient parallel repetition theorem,” presented at the TCC: Theory of Cryptography Conference, 2010, vol. 5978, pp. 1–18.","mla":"Håstad, Johan, et al. <i>An Efficient Parallel Repetition Theorem</i>. Vol. 5978, Springer, 2010, pp. 1–18, doi:<a href=\"https://doi.org/10.1007/978-3-642-11799-2_1\">10.1007/978-3-642-11799-2_1</a>.","apa":"Håstad, J., Pass, R., Wikström, D., &#38; Pietrzak, K. Z. (2010). An efficient parallel repetition theorem (Vol. 5978, pp. 1–18). Presented at the TCC: Theory of Cryptography Conference, Springer. <a href=\"https://doi.org/10.1007/978-3-642-11799-2_1\">https://doi.org/10.1007/978-3-642-11799-2_1</a>","ista":"Håstad J, Pass R, Wikström D, Pietrzak KZ. 2010. An efficient parallel repetition theorem. TCC: Theory of Cryptography Conference, LNCS, vol. 5978, 1–18.","short":"J. Håstad, R. Pass, D. Wikström, K.Z. Pietrzak, in:, Springer, 2010, pp. 1–18."},"month":"03","page":"1 - 18"},{"conference":{"name":"TCC: Theory of Cryptography Conference"},"citation":{"chicago":"Faust, Sebastian, Eike Kiltz, Krzysztof Z Pietrzak, and Guy Rothblum. “Leakage Resilient Signatures,” 5978:343–60. Springer, 2010. <a href=\"https://doi.org/10.1007/978-3-642-11799-2_21\">https://doi.org/10.1007/978-3-642-11799-2_21</a>.","ieee":"S. Faust, E. Kiltz, K. Z. Pietrzak, and G. Rothblum, “Leakage resilient signatures,” presented at the TCC: Theory of Cryptography Conference, 2010, vol. 5978, pp. 343–360.","ama":"Faust S, Kiltz E, Pietrzak KZ, Rothblum G. Leakage resilient signatures. In: Vol 5978. Springer; 2010:343-360. doi:<a href=\"https://doi.org/10.1007/978-3-642-11799-2_21\">10.1007/978-3-642-11799-2_21</a>","short":"S. Faust, E. Kiltz, K.Z. Pietrzak, G. Rothblum, in:, Springer, 2010, pp. 343–360.","ista":"Faust S, Kiltz E, Pietrzak KZ, Rothblum G. 2010. Leakage resilient signatures. TCC: Theory of Cryptography Conference, LNCS, vol. 5978, 343–360.","apa":"Faust, S., Kiltz, E., Pietrzak, K. Z., &#38; Rothblum, G. (2010). Leakage resilient signatures (Vol. 5978, pp. 343–360). Presented at the TCC: Theory of Cryptography Conference, Springer. <a href=\"https://doi.org/10.1007/978-3-642-11799-2_21\">https://doi.org/10.1007/978-3-642-11799-2_21</a>","mla":"Faust, Sebastian, et al. <i>Leakage Resilient Signatures</i>. Vol. 5978, Springer, 2010, pp. 343–60, doi:<a href=\"https://doi.org/10.1007/978-3-642-11799-2_21\">10.1007/978-3-642-11799-2_21</a>."},"volume":5978,"_id":"3234","title":"Leakage resilient signatures","doi":"10.1007/978-3-642-11799-2_21","publication_status":"published","year":"2010","page":"343 - 360","month":"03","alternative_title":["LNCS"],"day":"26","extern":1,"status":"public","type":"conference","abstract":[{"lang":"eng","text":"The strongest standard security notion for digital signature schemes is unforgeability under chosen message attacks. In practice, however, this notion can be insufficient due to &quot;side-channel attacks&quot; which exploit leakage of information about the secret internal state. In this work we put forward the notion of &quot;leakage-resilient signatures,&quot; which strengthens the standard security notion by giving the adversary the additional power to learn a bounded amount of arbitrary information about the secret state that was accessed during every signature generation. This notion naturally implies security against all side-channel attacks as long as the amount of information leaked on each invocation is bounded and &quot;only computation leaks information.&quot; The main result of this paper is a construction which gives a (tree-based, stateful) leakage-resilient signature scheme based on any 3-time signature scheme. The amount of information that our scheme can safely leak per signature generation is 1/3 of the information the underlying 3-time signature scheme can leak in total. Signature schemes that remain secure even if a bounded total amount of information is leaked were recently constructed, hence instantiating our construction with these schemes gives the first constructions of provably secure leakage-resilient signature schemes. The above construction assumes that the signing algorithm can sample truly random bits, and thus an implementation would need some special hardware (randomness gates). Simply generating this randomness using a leakage-resilient stream-cipher will in general not work. Our second contribution is a sound general principle to replace uniform random bits in any leakage-resilient construction with pseudorandom ones: run two leakage-resilient stream-ciphers (with independent keys) in parallel and then apply a two-source extractor to their outputs. "}],"publist_id":"3447","author":[{"first_name":"Sebastian","full_name":"Faust, Sebastian","last_name":"Faust"},{"last_name":"Kiltz","first_name":"Eike","full_name":"Kiltz, Eike"},{"full_name":"Krzysztof Pietrzak","id":"3E04A7AA-F248-11E8-B48F-1D18A9856A87","first_name":"Krzysztof Z","orcid":"0000-0002-9139-1654","last_name":"Pietrzak"},{"full_name":"Rothblum, Guy N","first_name":"Guy","last_name":"Rothblum"}],"quality_controlled":0,"publisher":"Springer","date_published":"2010-03-26T00:00:00Z","date_updated":"2021-01-12T07:41:59Z","date_created":"2018-12-11T12:02:10Z","intvolume":"      5978"},{"page":"21 - 40","month":"09","citation":{"short":"Y. Dodis, K.Z. Pietrzak, in:, Springer, 2010, pp. 21–40.","ista":"Dodis Y, Pietrzak KZ. 2010. Leakage resilient pseudorandom functions and side channel attacks on feistel networks. CRYPTO: International Cryptology Conference, LNCS, vol. 6223, 21–40.","mla":"Dodis, Yevgeniy, and Krzysztof Z. Pietrzak. <i>Leakage Resilient Pseudorandom Functions and Side Channel Attacks on Feistel Networks</i>. Vol. 6223, Springer, 2010, pp. 21–40, doi:<a href=\"https://doi.org/10.1007/978-3-642-14623-7_2\">10.1007/978-3-642-14623-7_2</a>.","apa":"Dodis, Y., &#38; Pietrzak, K. Z. (2010). Leakage resilient pseudorandom functions and side channel attacks on feistel networks (Vol. 6223, pp. 21–40). Presented at the CRYPTO: International Cryptology Conference, Springer. <a href=\"https://doi.org/10.1007/978-3-642-14623-7_2\">https://doi.org/10.1007/978-3-642-14623-7_2</a>","chicago":"Dodis, Yevgeniy, and Krzysztof Z Pietrzak. “Leakage Resilient Pseudorandom Functions and Side Channel Attacks on Feistel Networks,” 6223:21–40. Springer, 2010. <a href=\"https://doi.org/10.1007/978-3-642-14623-7_2\">https://doi.org/10.1007/978-3-642-14623-7_2</a>.","ama":"Dodis Y, Pietrzak KZ. Leakage resilient pseudorandom functions and side channel attacks on feistel networks. In: Vol 6223. Springer; 2010:21-40. doi:<a href=\"https://doi.org/10.1007/978-3-642-14623-7_2\">10.1007/978-3-642-14623-7_2</a>","ieee":"Y. Dodis and K. Z. Pietrzak, “Leakage resilient pseudorandom functions and side channel attacks on feistel networks,” presented at the CRYPTO: International Cryptology Conference, 2010, vol. 6223, pp. 21–40."},"conference":{"name":"CRYPTO: International Cryptology Conference"},"publication_status":"published","year":"2010","doi":"10.1007/978-3-642-14623-7_2","_id":"3235","volume":6223,"title":"Leakage resilient pseudorandom functions and side channel attacks on feistel networks","date_published":"2010-09-30T00:00:00Z","quality_controlled":0,"publisher":"Springer","author":[{"last_name":"Dodis","full_name":"Dodis, Yevgeniy","first_name":"Yevgeniy"},{"id":"3E04A7AA-F248-11E8-B48F-1D18A9856A87","full_name":"Krzysztof Pietrzak","first_name":"Krzysztof Z","last_name":"Pietrzak","orcid":"0000-0002-9139-1654"}],"date_created":"2018-12-11T12:02:10Z","intvolume":"      6223","date_updated":"2021-01-12T07:42:00Z","status":"public","type":"conference","day":"30","extern":1,"alternative_title":["LNCS"],"publist_id":"3445","abstract":[{"lang":"eng","text":"A cryptographic primitive is leakage-resilient, if it remains secure even if an adversary can learn a bounded amount of arbitrary information about the computation with every invocation. As a consequence, the physical implementation of a leakage-resilient primitive is secure against every side-channel as long as the amount of information leaked per invocation is bounded. In this paper we prove positive and negative results about the feasibility of constructing leakage-resilient pseudorandom functions and permutations (i.e. block-ciphers). Our results are three fold: 1. We construct (from any standard PRF) a PRF which satisfies a relaxed notion of leakage-resilience where (1) the leakage function is fixed (and not adaptively chosen with each query.) and (2) the computation is split into several steps which leak individually (a &quot;step&quot; will be the invocation of the underlying PRF.) 2. We prove that a Feistel network with a super-logarithmic number of rounds, each instantiated with a leakage-resilient PRF, is a leakage resilient PRP. This reduction also holds for the non-adaptive notion just discussed, we thus get a block-cipher which is leakage-resilient (against non-adaptive leakage). 3. We propose generic side-channel attacks against Feistel networks. The attacks are generic in the sense that they work for any round functions (e.g. uniformly random functions) and only require some simple leakage from the inputs to the round functions. For example we show how to invert an r round Feistel network over 2n bits making 4•(n+1) r-2 forward queries, if with each query we are also given as leakage the Hamming weight of the inputs to the r round functions. This complements the result from the previous item showing that a super-constant number of rounds is necessary."}]},{"month":"01","page":"595 - 612","doi":"10.1007/978-3-642-17373-8_34","publication_status":"published","year":"2010","title":"Leakage resilient ElGamal encryption","_id":"3237","volume":6477,"citation":{"ista":"Kiltz E, Pietrzak KZ. 2010. Leakage resilient ElGamal encryption. ASIACRYPT: Theory and Application of Cryptology and Information Security, LNCS, vol. 6477, 595–612.","short":"E. Kiltz, K.Z. Pietrzak, in:, Springer, 2010, pp. 595–612.","mla":"Kiltz, Eike, and Krzysztof Z. Pietrzak. <i>Leakage Resilient ElGamal Encryption</i>. Vol. 6477, Springer, 2010, pp. 595–612, doi:<a href=\"https://doi.org/10.1007/978-3-642-17373-8_34\">10.1007/978-3-642-17373-8_34</a>.","apa":"Kiltz, E., &#38; Pietrzak, K. Z. (2010). Leakage resilient ElGamal encryption (Vol. 6477, pp. 595–612). Presented at the ASIACRYPT: Theory and Application of Cryptology and Information Security, Springer. <a href=\"https://doi.org/10.1007/978-3-642-17373-8_34\">https://doi.org/10.1007/978-3-642-17373-8_34</a>","ieee":"E. Kiltz and K. Z. Pietrzak, “Leakage resilient ElGamal encryption,” presented at the ASIACRYPT: Theory and Application of Cryptology and Information Security, 2010, vol. 6477, pp. 595–612.","ama":"Kiltz E, Pietrzak KZ. Leakage resilient ElGamal encryption. In: Vol 6477. Springer; 2010:595-612. doi:<a href=\"https://doi.org/10.1007/978-3-642-17373-8_34\">10.1007/978-3-642-17373-8_34</a>","chicago":"Kiltz, Eike, and Krzysztof Z Pietrzak. “Leakage Resilient ElGamal Encryption,” 6477:595–612. Springer, 2010. <a href=\"https://doi.org/10.1007/978-3-642-17373-8_34\">https://doi.org/10.1007/978-3-642-17373-8_34</a>."},"conference":{"name":"ASIACRYPT: Theory and Application of Cryptology and Information Security"},"date_updated":"2021-01-12T07:42:01Z","intvolume":"      6477","date_created":"2018-12-11T12:02:11Z","date_published":"2010-01-14T00:00:00Z","publisher":"Springer","author":[{"full_name":"Kiltz, Eike","first_name":"Eike","last_name":"Kiltz"},{"full_name":"Krzysztof Pietrzak","first_name":"Krzysztof Z","id":"3E04A7AA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-9139-1654","last_name":"Pietrzak"}],"quality_controlled":0,"publist_id":"3444","abstract":[{"text":"Blinding is a popular and well-known countermeasure to protect public-key cryptosystems against side-channel attacks. The high level idea is to randomize an exponentiation in order to prevent multiple measurements of the same operation on different data, as such measurements might allow the adversary to learn the secret exponent. Several variants of blinding have been proposed in the literature, using additive or multiplicative secret-sharing to blind either the base or the exponent. These countermeasures usually aim at preventing particular side-channel attacks (mostly power analysis) and come without any formal security guarantee. In this work we investigate to which extend blinding can provide provable security against a general class of side-channel attacks. Surprisingly, it turns out that in the context of public-key encryption some blinding techniques are more suited than others. In particular, we consider a multiplicatively blinded version of ElGamal public-key encryption where - we prove that the scheme, instantiated over bilinear groups of prime order p (where p - 1 is not smooth) is leakage resilient in the generic-group model. Here we consider the model of chosen-ciphertext security in the presence of continuous leakage, i.e., the scheme remains chosen-ciphertext secure even if with every decryption query the adversary can learn a bounded amount (roughly log(p)/2 bits) of arbitrary, adversarially chosen information about the computation. - we conjecture that the scheme, instantiated over arbitrary groups of prime order p (where p - 1 is not smooth) is leakage resilient. Previous to this work no encryption scheme secure against continuous leakage was known. Constructing a scheme that can be proven secure in the standard model remains an interesting open problem. ","lang":"eng"}],"status":"public","type":"conference","alternative_title":["LNCS"],"day":"14","extern":1},{"abstract":[{"lang":"eng","text":"Olfactory responses of Drosophila undergo pronounced changes after eclosion. The flies develop attraction to odors to which they are exposed and aversion to other odors. Behavioral adaptation is correlated with changes in the firing pattern of olfactory receptor neurons (ORNs). In this article, we present an information-theoretic analysis of the firing pattern of ORNs. Flies reared in a synthetic odorless medium were transferred after eclosion to three different media: (i) a synthetic medium relatively devoid of odor cues, (ii) synthetic medium infused with a single odorant, and (iii) complex cornmeal medium rich in odors. Recordings were made from an identified sensillum (type II), and the Jensen-Shannon divergence (D(JS)) was used to assess quantitatively the differences between ensemble spike responses to different odors. Analysis shows that prolonged exposure to ethyl acetate and several related esters increases sensitivity to these esters but does not improve the ability of the fly to distinguish between them. Flies exposed to cornmeal display varied sensitivity to these odorants and at the same time develop greater capacity to distinguish between odors. Deprivation of odor experience on an odorless synthetic medium leads to a loss of both sensitivity and acuity. Rich olfactory experience thus helps to shape the ORNs response and enhances its discriminative power. The experiments presented here demonstrate an experience-dependent adaptation at the level of the receptor neuron."}],"publist_id":"3347","day":"01","extern":1,"type":"journal_article","status":"public","date_updated":"2021-01-12T07:42:27Z","date_created":"2018-12-11T12:02:31Z","intvolume":"       107","issue":"21","publisher":"National Academy of Sciences","quality_controlled":0,"author":[{"first_name":"Atulya","full_name":"Iyengar, Atulya","last_name":"Iyengar"},{"last_name":"Chakraborty Tuhin","full_name":"Chakraborty Tuhin, Subhra","first_name":"Subhra"},{"last_name":"Goswami","first_name":"Sarit","id":"3A578F32-F248-11E8-B48F-1D18A9856A87","full_name":"Sarit Goswami"},{"full_name":"Wu, Chun Fang","first_name":"Chun","last_name":"Wu"},{"last_name":"Siddiqi","first_name":"Obaid","full_name":"Siddiqi, Obaid"}],"date_published":"2010-01-01T00:00:00Z","_id":"3294","volume":107,"publication":"PNAS","title":"Post eclosion odor experience modifies olfactory receptor neuron coding in Drosophila","doi":"10.1073/pnas.1003856107","year":"2010","publication_status":"published","citation":{"mla":"Iyengar, Atulya, et al. “Post Eclosion Odor Experience Modifies Olfactory Receptor Neuron Coding in Drosophila.” <i>PNAS</i>, vol. 107, no. 21, National Academy of Sciences, 2010, pp. 9855–60, doi:<a href=\"https://doi.org/10.1073/pnas.1003856107\">10.1073/pnas.1003856107</a>.","apa":"Iyengar, A., Chakraborty Tuhin, S., Goswami, S., Wu, C., &#38; Siddiqi, O. (2010). Post eclosion odor experience modifies olfactory receptor neuron coding in Drosophila. <i>PNAS</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.1003856107\">https://doi.org/10.1073/pnas.1003856107</a>","short":"A. Iyengar, S. Chakraborty Tuhin, S. Goswami, C. Wu, O. Siddiqi, PNAS 107 (2010) 9855–60.","ista":"Iyengar A, Chakraborty Tuhin S, Goswami S, Wu C, Siddiqi O. 2010. Post eclosion odor experience modifies olfactory receptor neuron coding in Drosophila. PNAS. 107(21), 9855–60.","chicago":"Iyengar, Atulya, Subhra Chakraborty Tuhin, Sarit Goswami, Chun Wu, and Obaid Siddiqi. “Post Eclosion Odor Experience Modifies Olfactory Receptor Neuron Coding in Drosophila.” <i>PNAS</i>. National Academy of Sciences, 2010. <a href=\"https://doi.org/10.1073/pnas.1003856107\">https://doi.org/10.1073/pnas.1003856107</a>.","ama":"Iyengar A, Chakraborty Tuhin S, Goswami S, Wu C, Siddiqi O. Post eclosion odor experience modifies olfactory receptor neuron coding in Drosophila. <i>PNAS</i>. 2010;107(21):9855-9860. doi:<a href=\"https://doi.org/10.1073/pnas.1003856107\">10.1073/pnas.1003856107</a>","ieee":"A. Iyengar, S. Chakraborty Tuhin, S. Goswami, C. Wu, and O. Siddiqi, “Post eclosion odor experience modifies olfactory receptor neuron coding in Drosophila,” <i>PNAS</i>, vol. 107, no. 21. National Academy of Sciences, pp. 9855–60, 2010."},"month":"01","page":"9855 - 60"},{"publist_id":"3345","oa_version":"None","abstract":[{"lang":"eng","text":"Accurate computational representations of highly deformable surfaces are indispensable in the fields of computer animation, medical simulation, computer vision, digital modeling, and computational physics. The focus of this dissertation is on the animation of physics-based phenomena with highly detailed deformable surfaces represented by triangle meshes.\r\n \r\nWe first present results from an algorithm that generates continuum mechanics animations with intricate surface features. This method combines a finite element method with a tetrahedral mesh generator and a high resolution surface mesh, and it is orders of magnitude more efficient than previous approaches. Next, we present an efficient solution for the challenging problem of computing topological changes in detailed dynamic surface meshes. We then introduce a new physics-inspired surface tracking algorithm that is capable of preserving arbitrarily thin features and reproducing realistic fine-scale topological changes like Rayleigh-Plateau instabilities. This physics-inspired surface tracking technique also opens the door for a unique coupling between surficial finite element methods and volumetric finite difference methods, in order to simulate liquid surface tension phenomena more efficiently than any previous method. Due to its dramatic increase in computational resolution and efficiency, this method yielded the first computer simulations of a fully developed crown splash with droplet pinch off."}],"type":"dissertation","status":"public","extern":"1","day":"17","date_created":"2018-12-11T12:02:31Z","supervisor":[{"full_name":"Essa, Irfan","first_name":"Irfan","last_name":"Essa"},{"last_name":"Liu","first_name":"Karen","full_name":"Liu, Karen"},{"full_name":"Mucha, Peter","first_name":"Peter","last_name":"Mucha"},{"full_name":"Rossignac, Jarek","first_name":"Jarek","last_name":"Rossignac"}],"date_updated":"2023-02-23T11:21:00Z","date_published":"2010-11-17T00:00:00Z","author":[{"id":"3C61F1D2-F248-11E8-B48F-1D18A9856A87","full_name":"Wojtan, Christopher J","first_name":"Christopher J","orcid":"0000-0001-6646-5546","last_name":"Wojtan"}],"publisher":"Georgia Institute of Technology","year":"2010","publication_status":"published","language":[{"iso":"eng"}],"article_processing_charge":"No","_id":"3296","title":"Animating physical phenomena with embedded surface meshes","citation":{"chicago":"Wojtan, Chris. “Animating Physical Phenomena with Embedded Surface Meshes.” Georgia Institute of Technology, 2010.","ama":"Wojtan C. Animating physical phenomena with embedded surface meshes. 2010:1-175.","ieee":"C. Wojtan, “Animating physical phenomena with embedded surface meshes,” Georgia Institute of Technology, 2010.","apa":"Wojtan, C. (2010). <i>Animating physical phenomena with embedded surface meshes</i>. Georgia Institute of Technology.","mla":"Wojtan, Chris. <i>Animating Physical Phenomena with Embedded Surface Meshes</i>. Georgia Institute of Technology, 2010, pp. 1–175.","short":"C. Wojtan, Animating Physical Phenomena with Embedded Surface Meshes, Georgia Institute of Technology, 2010.","ista":"Wojtan C. 2010. Animating physical phenomena with embedded surface meshes. Georgia Institute of Technology."},"month":"11","main_file_link":[{"url":"http://hdl.handle.net/1853/37256"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","page":"1 - 175"},{"acknowledgement":"This work was supported in part by a Robert N. Noyce Stanford Graduate Fellowship and European Research Council grant 250152 (to D.B.W.) and by National Institutes of Health grant GM 28016 (to M.W.F.).\r\nWe thank Michael Desai for many ideas and discussions and are grateful to Joanna Masel and an anonymous reviewer for their helpful suggestions. ","oa":1,"citation":{"short":"D. Weissman, M. Feldman, D. Fisher, Genetics 186 (2010) 1389–1410.","ista":"Weissman D, Feldman M, Fisher D. 2010. The rate of fitness-valley crossing in sexual populations. Genetics. 186(4), 1389–1410.","apa":"Weissman, D., Feldman, M., &#38; Fisher, D. (2010). The rate of fitness-valley crossing in sexual populations. <i>Genetics</i>. Genetics Society of America. <a href=\"https://doi.org/10.1534/genetics.110.123240\">https://doi.org/10.1534/genetics.110.123240</a>","mla":"Weissman, Daniel, et al. “The Rate of Fitness-Valley Crossing in Sexual Populations.” <i>Genetics</i>, vol. 186, no. 4, Genetics Society of America, 2010, pp. 1389–410, doi:<a href=\"https://doi.org/10.1534/genetics.110.123240\">10.1534/genetics.110.123240</a>.","ieee":"D. Weissman, M. Feldman, and D. Fisher, “The rate of fitness-valley crossing in sexual populations,” <i>Genetics</i>, vol. 186, no. 4. Genetics Society of America, pp. 1389–1410, 2010.","ama":"Weissman D, Feldman M, Fisher D. The rate of fitness-valley crossing in sexual populations. <i>Genetics</i>. 2010;186(4):1389-1410. doi:<a href=\"https://doi.org/10.1534/genetics.110.123240\">10.1534/genetics.110.123240</a>","chicago":"Weissman, Daniel, Marcus Feldman, and Daniel Fisher. “The Rate of Fitness-Valley Crossing in Sexual Populations.” <i>Genetics</i>. Genetics Society of America, 2010. <a href=\"https://doi.org/10.1534/genetics.110.123240\">https://doi.org/10.1534/genetics.110.123240</a>."},"_id":"3303","publication":"Genetics","title":"The rate of fitness-valley crossing in sexual populations","publication_status":"published","doi":"10.1534/genetics.110.123240","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","scopus_import":1,"publist_id":"3337","oa_version":"Submitted Version","author":[{"last_name":"Weissman","first_name":"Daniel","full_name":"Weissman, Daniel","id":"2D0CE020-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Feldman, Marcus","first_name":"Marcus","last_name":"Feldman"},{"last_name":"Fisher","full_name":"Fisher, Daniel","first_name":"Daniel"}],"date_published":"2010-12-01T00:00:00Z","ec_funded":1,"intvolume":"       186","date_updated":"2021-01-12T07:42:31Z","issue":"4","project":[{"_id":"25B07788-B435-11E9-9278-68D0E5697425","grant_number":"250152","call_identifier":"FP7","name":"Limits to selection in biology and in evolutionary computation"}],"volume":186,"year":"2010","language":[{"iso":"eng"}],"page":"1389 - 1410","department":[{"_id":"NiBa"}],"month":"12","main_file_link":[{"open_access":"1","url":"http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998319/"}],"day":"01","type":"journal_article","status":"public","abstract":[{"text":"Biological traits result in part from interactions between different genetic loci. This can lead to sign epistasis, in which a beneficial adaptation involves a combination of individually deleterious or neutral mutations; in this case, a population must cross a “fitness valley” to adapt. Recombination can assist this process by combining mutations from different individuals or retard it by breaking up the adaptive combination. Here, we analyze the simplest fitness valley, in which an adaptation requires one mutation at each of two loci to provide a fitness benefit. We present a theoretical analysis of the effect of recombination on the valley-crossing process across the full spectrum of possible parameter regimes. We find that low recombination rates can speed up valley crossing relative to the asexual case, while higher recombination rates slow down valley crossing, with the transition between the two regimes occurring when the recombination rate between the loci is approximately equal to the selective advantage provided by the adaptation. In large populations, if the recombination rate is high and selection against single mutants is substantial, the time to cross the valley grows exponentially with population size, effectively meaning that the population cannot acquire the adaptation. Recombination at the optimal (low) rate can reduce the valley-crossing time by up to several orders of magnitude relative to that in an asexual population. ","lang":"eng"}],"quality_controlled":"1","publisher":"Genetics Society of America","date_created":"2018-12-11T12:02:33Z"},{"publist_id":"3334","abstract":[{"lang":"eng","text":"We use methods from combinatorics and algebraic statistics to study analogues of birth-and-death processes that have as their state space a finite subset of the m-dimensional lattice and for which the m matrices that record the transition probabilities in each of the lattice directions commute pairwise. One reason such processes are of interest is that the transition matrix is straightforward to diagonalize, and hence it is easy to compute n step transition probabilities. The set of commuting birth-and-death processes decomposes as a union of toric varieties, with the main component being the closure of all processes whose nearest neighbor transition probabilities are positive. We exhibit an explicit monomial parametrization for this main component, and we explore the boundary components using primary decomposition."}],"status":"public","type":"journal_article","day":"01","extern":1,"intvolume":"        20","date_created":"2018-12-11T12:02:35Z","date_updated":"2021-01-12T07:42:32Z","date_published":"2010-01-01T00:00:00Z","author":[{"last_name":"Evans","full_name":"Evans, Steven N","first_name":"Steven"},{"first_name":"Bernd","full_name":"Sturmfels, Bernd","last_name":"Sturmfels"},{"id":"49ADD78E-F248-11E8-B48F-1D18A9856A87","first_name":"Caroline","full_name":"Caroline Uhler","orcid":"0000-0002-7008-0216","last_name":"Uhler"}],"publisher":"Institute of Mathematical Statistics","quality_controlled":0,"year":"2010","publication_status":"published","doi":"10.1214/09-AAP615","volume":20,"_id":"3306","title":"Commuting birth and death processes","publication":"The Annals of Applied Probability","citation":{"chicago":"Evans, Steven, Bernd Sturmfels, and Caroline Uhler. “Commuting Birth and Death Processes.” <i>The Annals of Applied Probability</i>. Institute of Mathematical Statistics, 2010. <a href=\"https://doi.org/10.1214/09-AAP615\">https://doi.org/10.1214/09-AAP615</a>.","ama":"Evans S, Sturmfels B, Uhler C. Commuting birth and death processes. <i>The Annals of Applied Probability</i>. 2010;20:238-266. doi:<a href=\"https://doi.org/10.1214/09-AAP615\">10.1214/09-AAP615</a>","ieee":"S. Evans, B. Sturmfels, and C. Uhler, “Commuting birth and death processes,” <i>The Annals of Applied Probability</i>, vol. 20. Institute of Mathematical Statistics, pp. 238–266, 2010.","short":"S. Evans, B. Sturmfels, C. Uhler, The Annals of Applied Probability 20 (2010) 238–266.","ista":"Evans S, Sturmfels B, Uhler C. 2010. Commuting birth and death processes. The Annals of Applied Probability. 20, 238–266.","mla":"Evans, Steven, et al. “Commuting Birth and Death Processes.” <i>The Annals of Applied Probability</i>, vol. 20, Institute of Mathematical Statistics, 2010, pp. 238–66, doi:<a href=\"https://doi.org/10.1214/09-AAP615\">10.1214/09-AAP615</a>.","apa":"Evans, S., Sturmfels, B., &#38; Uhler, C. (2010). Commuting birth and death processes. <i>The Annals of Applied Probability</i>. Institute of Mathematical Statistics. <a href=\"https://doi.org/10.1214/09-AAP615\">https://doi.org/10.1214/09-AAP615</a>"},"acknowledgement":"Steven N. Evans was supported in part by NSF Grants DMS-04-05778 and DMS-09-07630. Bernd Sturmfels was supported in part by NSF Grants DMS-04-56960 and DMS-07-57236. Caroline Uhler was supported by an International Fulbright Science and Technology Fellowship.","oa":1,"month":"01","main_file_link":[{"open_access":"1","url":"http://arxiv.org/abs/0812.2724"}],"page":"238 - 266"},{"publication_status":"published","year":"2010","doi":"10.1007/s10463-010-0295-4","volume":62,"_id":"3308","publication":"Annals of the Institute of Statistical Mathematics","title":"Multivariate Gaussians, semidefinite matrix completion, and convex algebraic geometry","citation":{"mla":"Sturmfels, Bernd, and Caroline Uhler. “Multivariate Gaussians, Semidefinite Matrix Completion, and Convex Algebraic Geometry.” <i>Annals of the Institute of Statistical Mathematics</i>, vol. 62, no. 4, Springer, 2010, pp. 603–38, doi:<a href=\"https://doi.org/10.1007/s10463-010-0295-4\">10.1007/s10463-010-0295-4</a>.","apa":"Sturmfels, B., &#38; Uhler, C. (2010). Multivariate Gaussians, semidefinite matrix completion, and convex algebraic geometry. <i>Annals of the Institute of Statistical Mathematics</i>. Springer. <a href=\"https://doi.org/10.1007/s10463-010-0295-4\">https://doi.org/10.1007/s10463-010-0295-4</a>","ista":"Sturmfels B, Uhler C. 2010. Multivariate Gaussians, semidefinite matrix completion, and convex algebraic geometry. Annals of the Institute of Statistical Mathematics. 62(4), 603–638.","short":"B. Sturmfels, C. Uhler, Annals of the Institute of Statistical Mathematics 62 (2010) 603–638.","ama":"Sturmfels B, Uhler C. Multivariate Gaussians, semidefinite matrix completion, and convex algebraic geometry. <i>Annals of the Institute of Statistical Mathematics</i>. 2010;62(4):603-638. doi:<a href=\"https://doi.org/10.1007/s10463-010-0295-4\">10.1007/s10463-010-0295-4</a>","ieee":"B. Sturmfels and C. Uhler, “Multivariate Gaussians, semidefinite matrix completion, and convex algebraic geometry,” <i>Annals of the Institute of Statistical Mathematics</i>, vol. 62, no. 4. Springer, pp. 603–638, 2010.","chicago":"Sturmfels, Bernd, and Caroline Uhler. “Multivariate Gaussians, Semidefinite Matrix Completion, and Convex Algebraic Geometry.” <i>Annals of the Institute of Statistical Mathematics</i>. Springer, 2010. <a href=\"https://doi.org/10.1007/s10463-010-0295-4\">https://doi.org/10.1007/s10463-010-0295-4</a>."},"acknowledgement":"B. Sturmfels is supported in part by NSF grants DMS-0456960 and DMS-0757236. C. Uhler is supported by an International Fulbright Science and Technology Fellowship.","oa":1,"month":"08","main_file_link":[{"open_access":"1","url":"http://arxiv.org/abs/0906.3529"}],"page":"603 - 638","publist_id":"3332","abstract":[{"text":"We study multivariate normal models that are described by linear constraints on the inverse of the covariance matrix. Maximum likelihood estimation for such models leads to the problem of maximizing the determinant function over a spectrahedron, and to the problem of characterizing the image of the positive definite cone under an arbitrary linear projection. These problems at the interface of statistics and optimization are here examined from the perspective of convex algebraic geometry.","lang":"eng"}],"status":"public","type":"journal_article","extern":1,"day":"01","issue":"4","intvolume":"        62","date_created":"2018-12-11T12:02:35Z","date_updated":"2021-01-12T07:42:33Z","date_published":"2010-08-01T00:00:00Z","author":[{"first_name":"Bernd","full_name":"Sturmfels, Bernd","last_name":"Sturmfels"},{"first_name":"Caroline","id":"49ADD78E-F248-11E8-B48F-1D18A9856A87","full_name":"Caroline Uhler","orcid":"0000-0002-7008-0216","last_name":"Uhler"}],"quality_controlled":0,"publisher":"Springer"},{"status":"public","type":"journal_article","extern":1,"day":"01","pubrep_id":"74","publist_id":"3000","abstract":[{"lang":"eng","text":"Model checking transactional memories (TMs) is difficult because of the unbounded number, length, and delay of concurrent transactions, as well as the unbounded size of the memory. We show that, under certain conditions satisfied by most TMs we know of, the model checking problem can be reduced to a finite-state problem, and we illustrate the use of the method by proving the correctness of several TMs, including two-phase locking, DSTM, and TL2. The safety properties we consider include strict serializability and opacity; the liveness properties include obstruction freedom, livelock freedom, and wait freedom. Our main contribution lies in the structure of the proofs, which are largely automated and not restricted to the TMs mentioned above. In a first step we show that every TM that enjoys certain structural properties either violates a requirement on some program with two threads and two shared variables, or satisfies the requirement on all programs. In the second step, we use a model checker to prove the requirement for the TM applied to a most general program with two threads and two variables. In the safety case, the model checker checks language inclusion between two finite-state transition systems, a nondeterministic transition system representing the given TM applied to a most general program, and a deterministic transition system representing a most liberal safe TM applied to the same program. The given TM transition system is nondeterministic because a TM can be used with different contention managers, which resolve conflicts differently. In the liveness case, the model checker analyzes fairness conditions on the given TM transition system."}],"date_published":"2010-03-01T00:00:00Z","publisher":"Springer","author":[{"first_name":"Rachid","full_name":"Guerraoui, Rachid","last_name":"Guerraoui"},{"first_name":"Thomas A","id":"40876CD8-F248-11E8-B48F-1D18A9856A87","full_name":"Thomas Henzinger","orcid":"0000−0002−2985−7724","last_name":"Henzinger"},{"last_name":"Singh","id":"4DAE2708-F248-11E8-B48F-1D18A9856A87","full_name":"Vasu Singh","first_name":"Vasu"}],"quality_controlled":0,"issue":"3","date_updated":"2021-01-12T07:43:14Z","intvolume":"        22","date_created":"2018-12-11T12:03:08Z","citation":{"apa":"Guerraoui, R., Henzinger, T. A., &#38; Singh, V. (2010). Model checking transactional memories. <i>Distributed Computing</i>. Springer. <a href=\"https://doi.org/10.1007/s00446-009-0092-6\">https://doi.org/10.1007/s00446-009-0092-6</a>","mla":"Guerraoui, Rachid, et al. “Model Checking Transactional Memories.” <i>Distributed Computing</i>, vol. 22, no. 3, Springer, 2010, pp. 129–45, doi:<a href=\"https://doi.org/10.1007/s00446-009-0092-6\">10.1007/s00446-009-0092-6</a>.","short":"R. Guerraoui, T.A. Henzinger, V. Singh, Distributed Computing 22 (2010) 129–145.","ista":"Guerraoui R, Henzinger TA, Singh V. 2010. Model checking transactional memories. Distributed Computing. 22(3), 129–145.","chicago":"Guerraoui, Rachid, Thomas A Henzinger, and Vasu Singh. “Model Checking Transactional Memories.” <i>Distributed Computing</i>. Springer, 2010. <a href=\"https://doi.org/10.1007/s00446-009-0092-6\">https://doi.org/10.1007/s00446-009-0092-6</a>.","ieee":"R. Guerraoui, T. A. Henzinger, and V. Singh, “Model checking transactional memories,” <i>Distributed Computing</i>, vol. 22, no. 3. Springer, pp. 129–145, 2010.","ama":"Guerraoui R, Henzinger TA, Singh V. Model checking transactional memories. <i>Distributed Computing</i>. 2010;22(3):129-145. doi:<a href=\"https://doi.org/10.1007/s00446-009-0092-6\">10.1007/s00446-009-0092-6</a>"},"acknowledgement":"This research was supported by the Swiss National Science Foundation. This paper is an extended and revised version of our previous work on model checking transactional memories.","doi":"10.1007/s00446-009-0092-6","publication_status":"published","year":"2010","_id":"3402","publication":"Distributed Computing","title":"Model checking transactional memories","volume":22,"page":"129 - 145","main_file_link":[{"url":"http://infoscience.epfl.ch/record/117513/files/PLDI_paper.pdf","open_access":"0"}],"month":"03"},{"date_published":"2010-12-22T00:00:00Z","quality_controlled":0,"author":[{"last_name":"Pleydell Bouverie","full_name":"Pleydell-Bouverie, Barty","first_name":"Barty"},{"full_name":"Jozsef Csicsvari","id":"3FA14672-F248-11E8-B48F-1D18A9856A87","first_name":"Jozsef L","orcid":"0000-0002-5193-4036","last_name":"Csicsvari"}],"publisher":"Elsevier","issue":"6","date_updated":"2019-05-10T12:19:51Z","date_created":"2018-12-11T12:03:08Z","intvolume":"        68","type":"review","status":"public","extern":1,"day":"22","publist_id":"2999","abstract":[{"lang":"eng","text":"Rate remapping is a conjunctive code that potentially enables hippocampal place cells to jointly represent spatial and nonspatial information. In this issue of Neuron, Rennó-Costa et al. introduce a theoretical model wherein the convergence of the medial and lateral entorhinal excitatory inputs, combined with local inhibition, explains hippocampal rate remapping. © 2010 Elsevier Inc."}],"page":"1015 - 1016","month":"12","citation":{"ama":"Pleydell Bouverie B, Csicsvari JL. Rate remapping: When the code goes beyond space (preview). <i>Neuron</i>. 2010;68(6):1015-1016. doi:<a href=\"https://doi.org/10.1016/j.neuron.2010.12.011\">10.1016/j.neuron.2010.12.011</a>","ieee":"B. Pleydell Bouverie and J. L. Csicsvari, “Rate remapping: When the code goes beyond space (preview),” <i>Neuron</i>, vol. 68, no. 6. Elsevier, pp. 1015–1016, 2010.","chicago":"Pleydell Bouverie, Barty, and Jozsef L Csicsvari. “Rate Remapping: When the Code Goes beyond Space (Preview).” <i>Neuron</i>. Elsevier, 2010. <a href=\"https://doi.org/10.1016/j.neuron.2010.12.011\">https://doi.org/10.1016/j.neuron.2010.12.011</a>.","apa":"Pleydell Bouverie, B., &#38; Csicsvari, J. L. (2010). Rate remapping: When the code goes beyond space (preview). <i>Neuron</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.neuron.2010.12.011\">https://doi.org/10.1016/j.neuron.2010.12.011</a>","mla":"Pleydell Bouverie, Barty, and Jozsef L. Csicsvari. “Rate Remapping: When the Code Goes beyond Space (Preview).” <i>Neuron</i>, vol. 68, no. 6, Elsevier, 2010, pp. 1015–16, doi:<a href=\"https://doi.org/10.1016/j.neuron.2010.12.011\">10.1016/j.neuron.2010.12.011</a>.","ista":"Pleydell Bouverie B, Csicsvari JL. 2010. Rate remapping: When the code goes beyond space (preview). Neuron. 68(6), 1015–1016.","short":"B. Pleydell Bouverie, J.L. Csicsvari, Neuron 68 (2010) 1015–1016."},"doi":"10.1016/j.neuron.2010.12.011","publication_status":"published","year":"2010","publication":"Neuron","_id":"3403","title":"Rate remapping: When the code goes beyond space (preview)","volume":68},{"page":"7759 - 7772","month":"11","citation":{"chicago":"Stawski, Philipp, Harald L Janovjak, and Dirk Trauner. “Pharmacology of Ionotropic Glutamate Receptors: A Structural Perspective.” <i>Bioorganic and Medicinal Chemistry</i>. Elsevier, 2010. <a href=\"https://doi.org/10.1016/j.bmc.2010.09.012\">https://doi.org/10.1016/j.bmc.2010.09.012</a>.","ama":"Stawski P, Janovjak HL, Trauner D. Pharmacology of ionotropic glutamate receptors: a structural perspective. <i>Bioorganic and Medicinal Chemistry</i>. 2010;18(22):7759-7772. doi:<a href=\"https://doi.org/10.1016/j.bmc.2010.09.012\">10.1016/j.bmc.2010.09.012</a>","ieee":"P. Stawski, H. L. Janovjak, and D. Trauner, “Pharmacology of ionotropic glutamate receptors: a structural perspective,” <i>Bioorganic and Medicinal Chemistry</i>, vol. 18, no. 22. Elsevier, pp. 7759–7772, 2010.","ista":"Stawski P, Janovjak HL, Trauner D. 2010. Pharmacology of ionotropic glutamate receptors: a structural perspective. Bioorganic and Medicinal Chemistry. 18(22), 7759–7772.","short":"P. Stawski, H.L. Janovjak, D. Trauner, Bioorganic and Medicinal Chemistry 18 (2010) 7759–7772.","apa":"Stawski, P., Janovjak, H. L., &#38; Trauner, D. (2010). Pharmacology of ionotropic glutamate receptors: a structural perspective. <i>Bioorganic and Medicinal Chemistry</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.bmc.2010.09.012\">https://doi.org/10.1016/j.bmc.2010.09.012</a>","mla":"Stawski, Philipp, et al. “Pharmacology of Ionotropic Glutamate Receptors: A Structural Perspective.” <i>Bioorganic and Medicinal Chemistry</i>, vol. 18, no. 22, Elsevier, 2010, pp. 7759–72, doi:<a href=\"https://doi.org/10.1016/j.bmc.2010.09.012\">10.1016/j.bmc.2010.09.012</a>."},"publication":"Bioorganic and Medicinal Chemistry","_id":"3406","title":"Pharmacology of ionotropic glutamate receptors: a structural perspective","volume":18,"publication_status":"published","year":"2010","doi":"10.1016/j.bmc.2010.09.012","quality_controlled":0,"author":[{"first_name":"Philipp","full_name":"Stawski, Philipp","last_name":"Stawski"},{"orcid":"0000-0002-8023-9315","last_name":"Janovjak","full_name":"Harald Janovjak","first_name":"Harald L","id":"33BA6C30-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Trauner","full_name":"Trauner, Dirk","first_name":"Dirk"}],"publisher":"Elsevier","date_published":"2010-11-15T00:00:00Z","date_created":"2018-12-11T12:03:10Z","intvolume":"        18","date_updated":"2019-04-26T07:22:27Z","issue":"22","day":"15","extern":1,"type":"review","status":"public","abstract":[{"text":"The impact of structural biology on the design of ligands (agonists, antagonists and modulators) for ionotropic glutamate receptors is reviewed.","lang":"eng"}],"publist_id":"2996"},{"citation":{"chicago":"Janovjak, Harald L, Stephanie Szobota, Claire Wyart, Dirk Trauner, and Ehud Isacoff. “A Light-Gated, Potassium-Selective Glutamate Receptor for the Optical Inhibition of Neuronal Firing.” <i>Nature Neuroscience</i>. Nature Publishing Group, 2010. <a href=\"https://doi.org/10.1038/nn.2589\">https://doi.org/10.1038/nn.2589</a>.","ama":"Janovjak HL, Szobota S, Wyart C, Trauner D, Isacoff E. A light-gated, potassium-selective glutamate receptor for the optical inhibition of neuronal firing. <i>Nature Neuroscience</i>. 2010;13:1027-1032. doi:<a href=\"https://doi.org/10.1038/nn.2589\">10.1038/nn.2589</a>","ieee":"H. L. Janovjak, S. Szobota, C. Wyart, D. Trauner, and E. Isacoff, “A light-gated, potassium-selective glutamate receptor for the optical inhibition of neuronal firing,” <i>Nature Neuroscience</i>, vol. 13. Nature Publishing Group, pp. 1027–1032, 2010.","ista":"Janovjak HL, Szobota S, Wyart C, Trauner D, Isacoff E. 2010. A light-gated, potassium-selective glutamate receptor for the optical inhibition of neuronal firing. Nature Neuroscience. 13, 1027–1032.","short":"H.L. Janovjak, S. Szobota, C. Wyart, D. Trauner, E. Isacoff, Nature Neuroscience 13 (2010) 1027–1032.","mla":"Janovjak, Harald L., et al. “A Light-Gated, Potassium-Selective Glutamate Receptor for the Optical Inhibition of Neuronal Firing.” <i>Nature Neuroscience</i>, vol. 13, Nature Publishing Group, 2010, pp. 1027–32, doi:<a href=\"https://doi.org/10.1038/nn.2589\">10.1038/nn.2589</a>.","apa":"Janovjak, H. L., Szobota, S., Wyart, C., Trauner, D., &#38; Isacoff, E. (2010). A light-gated, potassium-selective glutamate receptor for the optical inhibition of neuronal firing. <i>Nature Neuroscience</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/nn.2589\">https://doi.org/10.1038/nn.2589</a>"},"_id":"3407","publication":"Nature Neuroscience","title":"A light-gated, potassium-selective glutamate receptor for the optical inhibition of neuronal firing","volume":13,"year":"2010","publication_status":"published","doi":"10.1038/nn.2589","page":"1027 - 1032","month":"06","extern":1,"day":"27","status":"public","type":"journal_article","abstract":[{"lang":"eng","text":"Genetically targeted light-activated ion channels and pumps make it possible to determine the role of specific neurons in neuronal circuits, information processing and behavior. We developed a K+-selective ionotropic glutamate receptor that reversibly inhibits neuronal activity in response to light in dissociated neurons and brain slice and also reversibly suppresses behavior in zebrafish. The receptor is a chimera of the pore region of a K+-selective bacterial glutamate receptor and the ligand-binding domain of a light-gated mammalian kainate receptor. This hyperpolarizing light-gated channel, HyLighter, is turned on by a brief light pulse at one wavelength and turned off by a pulse at a second wavelength. The control is obtained at moderate intensity. After optical activation, the photocurrent and optical silencing of activity persists in the dark for extended periods. The low light requirement and bi-stability of HyLighter represent advantages for the dissection of neural circuitry."}],"publist_id":"2995","publisher":"Nature Publishing Group","quality_controlled":0,"author":[{"last_name":"Janovjak","orcid":"0000-0002-8023-9315","full_name":"Harald Janovjak","first_name":"Harald L","id":"33BA6C30-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Szobota","first_name":"Stephanie","full_name":"Szobota, Stephanie"},{"full_name":"Wyart, Claire","first_name":"Claire","last_name":"Wyart"},{"first_name":"Dirk","full_name":"Trauner, Dirk","last_name":"Trauner"},{"last_name":"Isacoff","first_name":"Ehud","full_name":"Isacoff, Ehud Y"}],"date_published":"2010-06-27T00:00:00Z","date_created":"2018-12-11T12:03:10Z","intvolume":"        13","date_updated":"2021-01-12T07:43:16Z"},{"title":"Lecture notes for 2010 summer school on Quantitative Evolutionary and Comparative Genomics","_id":"3430","year":"2010","publication_status":"published","oa":1,"conference":{"name":"Summer School on Quantitative Evolutionary and Comparative Genomics"},"citation":{"ama":"Tkačik G. Lecture notes for 2010 summer school on Quantitative Evolutionary and Comparative Genomics. In: Elsevier; 2010.","ieee":"G. Tkačik, “Lecture notes for 2010 summer school on Quantitative Evolutionary and Comparative Genomics,” presented at the Summer School on Quantitative Evolutionary and Comparative Genomics, 2010.","chicago":"Tkačik, Gašper. “Lecture Notes for 2010 Summer School on Quantitative Evolutionary and Comparative Genomics.” Elsevier, 2010.","ista":"Tkačik G. 2010. Lecture notes for 2010 summer school on Quantitative Evolutionary and Comparative Genomics. Summer School on Quantitative Evolutionary and Comparative Genomics.","short":"G. Tkačik, in:, Elsevier, 2010.","mla":"Tkačik, Gašper. <i>Lecture Notes for 2010 Summer School on Quantitative Evolutionary and Comparative Genomics</i>. Elsevier, 2010.","apa":"Tkačik, G. (2010). Lecture notes for 2010 summer school on Quantitative Evolutionary and Comparative Genomics. Presented at the Summer School on Quantitative Evolutionary and Comparative Genomics, Elsevier."},"main_file_link":[{"open_access":"1","url":"http://arxiv.org/pdf/1006.4291"}],"month":"06","abstract":[{"lang":"eng","text":"These are notes for a set of 7 two-hour lectures given at the 2010 Summer School on Quantitative Evolutionary and Comparative Genomics at OIST, Okinawa, Japan. The emphasis is on understanding how biological systems process information. We take a physicist's approach of looking for simple phenomenological descriptions that can address the questions of biological function without necessarily modeling all (mostly unknown) microscopic details; the example that is developed throughout the notes is transcriptional regulation in genetic regulatory networks. We present tools from information theory and statistical physics that can be used to analyze noisy nonlinear biological networks, and build generative and predictive models of regulatory processes."}],"publist_id":"2970","day":"22","extern":1,"status":"public","type":"conference","date_updated":"2021-01-12T07:43:25Z","date_created":"2018-12-11T12:03:17Z","quality_controlled":0,"publisher":"Elsevier","author":[{"id":"3D494DCA-F248-11E8-B48F-1D18A9856A87","first_name":"Gasper","full_name":"Gasper Tkacik","orcid":"0000-0002-6699-1455","last_name":"Tkacik"}],"date_published":"2010-06-22T00:00:00Z"},{"date_updated":"2021-01-12T07:43:29Z","date_created":"2018-12-11T12:03:21Z","intvolume":"        13","issue":"8","publisher":"Nature Publishing Group","author":[{"last_name":"Dupret","first_name":"David","full_name":"Dupret, David"},{"last_name":"O'Neill","first_name":"Joseph","id":"426376DC-F248-11E8-B48F-1D18A9856A87","full_name":"Joseph O'Neill"},{"first_name":"Barty","full_name":"Pleydell-Bouverie, Barty","last_name":"Pleydell Bouverie"},{"full_name":"Jozsef Csicsvari","first_name":"Jozsef L","id":"3FA14672-F248-11E8-B48F-1D18A9856A87","last_name":"Csicsvari","orcid":"0000-0002-5193-4036"}],"quality_controlled":0,"date_published":"2010-08-01T00:00:00Z","abstract":[{"text":"The hippocampus is an important brain circuit for spatial memory and the spatially selective spiking of hippocampal neuronal assemblies is thought to provide a mnemonic representation of space. We found that remembering newly learnt goal locations required NMDA receptorĝ€&quot;dependent stabilization and enhanced reactivation of goal-related hippocampal assemblies. During spatial learning, place-related firing patterns in the CA1, but not CA3, region of the rat hippocampus were reorganized to represent new goal locations. Such reorganization did not occur when goals were marked by visual cues. The stabilization and successful retrieval of these newly acquired CA1 representations of behaviorally relevant places was NMDAR dependent and necessary for subsequent memory retention performance. Goal-related assembly patterns associated with sharp wave/ripple network oscillations, during both learning and subsequent rest periods, predicted memory performance. Together, these results suggest that the reorganization and reactivation of assembly firing patterns in the hippocampus represent the formation and expression of new spatial memory traces. © 2010 Nature America, Inc. All rights reserved.","lang":"eng"}],"publist_id":"2946","extern":1,"day":"01","type":"journal_article","status":"public","month":"08","page":"995 - 1002","_id":"3441","volume":13,"title":"The reorganization and reactivation of hippocampal maps predict spatial memory performance","publication":"Nature Neuroscience","doi":"10.1038/nn.2599","publication_status":"published","year":"2010","acknowledgement":"Discussed in the News and Views section of the journal by Jeffery and Cacucci\n","citation":{"ama":"Dupret D, O’Neill J, Pleydell Bouverie B, Csicsvari JL. The reorganization and reactivation of hippocampal maps predict spatial memory performance. <i>Nature Neuroscience</i>. 2010;13(8):995-1002. doi:<a href=\"https://doi.org/10.1038/nn.2599\">10.1038/nn.2599</a>","ieee":"D. Dupret, J. O’Neill, B. Pleydell Bouverie, and J. L. Csicsvari, “The reorganization and reactivation of hippocampal maps predict spatial memory performance,” <i>Nature Neuroscience</i>, vol. 13, no. 8. Nature Publishing Group, pp. 995–1002, 2010.","chicago":"Dupret, David, Joseph O’Neill, Barty Pleydell Bouverie, and Jozsef L Csicsvari. “The Reorganization and Reactivation of Hippocampal Maps Predict Spatial Memory Performance.” <i>Nature Neuroscience</i>. Nature Publishing Group, 2010. <a href=\"https://doi.org/10.1038/nn.2599\">https://doi.org/10.1038/nn.2599</a>.","short":"D. Dupret, J. O’Neill, B. Pleydell Bouverie, J.L. Csicsvari, Nature Neuroscience 13 (2010) 995–1002.","ista":"Dupret D, O’Neill J, Pleydell Bouverie B, Csicsvari JL. 2010. The reorganization and reactivation of hippocampal maps predict spatial memory performance. Nature Neuroscience. 13(8), 995–1002.","mla":"Dupret, David, et al. “The Reorganization and Reactivation of Hippocampal Maps Predict Spatial Memory Performance.” <i>Nature Neuroscience</i>, vol. 13, no. 8, Nature Publishing Group, 2010, pp. 995–1002, doi:<a href=\"https://doi.org/10.1038/nn.2599\">10.1038/nn.2599</a>.","apa":"Dupret, D., O’Neill, J., Pleydell Bouverie, B., &#38; Csicsvari, J. L. (2010). The reorganization and reactivation of hippocampal maps predict spatial memory performance. <i>Nature Neuroscience</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/nn.2599\">https://doi.org/10.1038/nn.2599</a>"}},{"month":"05","page":"220 - 229","publication_status":"published","year":"2010","doi":"10.1016/j.tins.2010.01.006","publication":"Trends in Neurosciences","_id":"3442","title":"Play it again: reactivation of waking experience and memory","volume":33,"citation":{"chicago":"O’Neill, Joseph, Barty Pleydell Bouverie, David Dupret, and Jozsef L Csicsvari. “Play It Again: Reactivation of Waking Experience and Memory.” <i>Trends in Neurosciences</i>. Elsevier, 2010. <a href=\"https://doi.org/10.1016/j.tins.2010.01.006\">https://doi.org/10.1016/j.tins.2010.01.006</a>.","ieee":"J. O’Neill, B. Pleydell Bouverie, D. Dupret, and J. L. Csicsvari, “Play it again: reactivation of waking experience and memory,” <i>Trends in Neurosciences</i>, vol. 33, no. 5. Elsevier, pp. 220–229, 2010.","ama":"O’Neill J, Pleydell Bouverie B, Dupret D, Csicsvari JL. Play it again: reactivation of waking experience and memory. <i>Trends in Neurosciences</i>. 2010;33(5):220-229. doi:<a href=\"https://doi.org/10.1016/j.tins.2010.01.006\">10.1016/j.tins.2010.01.006</a>","mla":"O’Neill, Joseph, et al. “Play It Again: Reactivation of Waking Experience and Memory.” <i>Trends in Neurosciences</i>, vol. 33, no. 5, Elsevier, 2010, pp. 220–29, doi:<a href=\"https://doi.org/10.1016/j.tins.2010.01.006\">10.1016/j.tins.2010.01.006</a>.","apa":"O’Neill, J., Pleydell Bouverie, B., Dupret, D., &#38; Csicsvari, J. L. (2010). Play it again: reactivation of waking experience and memory. <i>Trends in Neurosciences</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.tins.2010.01.006\">https://doi.org/10.1016/j.tins.2010.01.006</a>","ista":"O’Neill J, Pleydell Bouverie B, Dupret D, Csicsvari JL. 2010. Play it again: reactivation of waking experience and memory. Trends in Neurosciences. 33(5), 220–229.","short":"J. O’Neill, B. Pleydell Bouverie, D. Dupret, J.L. Csicsvari, Trends in Neurosciences 33 (2010) 220–229."},"issue":"5","intvolume":"        33","date_created":"2018-12-11T12:03:21Z","date_updated":"2021-01-12T07:43:29Z","date_published":"2010-05-01T00:00:00Z","author":[{"id":"426376DC-F248-11E8-B48F-1D18A9856A87","first_name":"Joseph","full_name":"Joseph O'Neill","last_name":"O'Neill"},{"full_name":"Pleydell-Bouverie, Barty","first_name":"Barty","last_name":"Pleydell Bouverie"},{"last_name":"Dupret","first_name":"David","full_name":"Dupret, David"},{"id":"3FA14672-F248-11E8-B48F-1D18A9856A87","full_name":"Jozsef Csicsvari","first_name":"Jozsef L","last_name":"Csicsvari","orcid":"0000-0002-5193-4036"}],"publisher":"Elsevier","quality_controlled":0,"publist_id":"2945","abstract":[{"lang":"eng","text":"Episodic and spatial memories each involve the encoding of complex associations in hippocampal neuronal circuits. Such memory traces could be stabilised from short- to long-term forms by consolidation processes involving the 'reactivation' of the original network firing patterns during sleep and rest. Waking experience can be replayed in many different brain areas, but an important role for the hippocampus lies in the organisation of the 'reactivation' process. Emerging evidence suggests that sharp wave/ripple (SWR) events in the hippocampus could coordinate the reactivation of memory traces and direct their reinstatement in cortical circuits. Although the mechanisms remain uncertain, there is a growing consensus that such SWR-directed reactivation of brain-wide memory traces could underlie memory consolidation. © 2010 Elsevier Ltd."}],"status":"public","type":"journal_article","extern":1,"day":"01"},{"month":"01","year":"2010","publication_status":"published","_id":"3459","publication":"Physiologie Des Menschen","title":"Grundlagen zellulärer Erregbarkeit","citation":{"chicago":"Fakler, Bernd, and Peter M Jonas. “Grundlagen Zellulärer Erregbarkeit.” In <i>Physiologie Des Menschen</i>, edited by R. Schmidt, M. Heckmann, and Florian Lang. Springer, 2010.","ieee":"B. Fakler and P. M. Jonas, “Grundlagen zellulärer Erregbarkeit,” in <i>Physiologie Des Menschen</i>, R. Schmidt, M. Heckmann, and F. Lang, Eds. Springer, 2010.","ama":"Fakler B, Jonas PM. Grundlagen zellulärer Erregbarkeit. In: Schmidt R, Heckmann M, Lang F, eds. <i>Physiologie Des Menschen</i>. Springer; 2010.","apa":"Fakler, B., &#38; Jonas, P. M. (2010). Grundlagen zellulärer Erregbarkeit. In R. Schmidt, M. Heckmann, &#38; F. Lang (Eds.), <i>Physiologie Des Menschen</i>. Springer.","mla":"Fakler, Bernd, and Peter M. Jonas. “Grundlagen Zellulärer Erregbarkeit.” <i>Physiologie Des Menschen</i>, edited by R. Schmidt et al., Springer, 2010.","short":"B. Fakler, P.M. Jonas, in:, R. Schmidt, M. Heckmann, F. Lang (Eds.), Physiologie Des Menschen, Springer, 2010.","ista":"Fakler B, Jonas PM. 2010.Grundlagen zellulärer Erregbarkeit. In: Physiologie Des Menschen. ."},"editor":[{"first_name":"R.","full_name":"Schmidt, R. F.","last_name":"Schmidt"},{"full_name":"Heckmann, M.","first_name":"M.","last_name":"Heckmann"},{"full_name":"Lang, Florian","first_name":"Florian","last_name":"Lang"}],"date_created":"2018-12-11T12:03:26Z","date_updated":"2021-01-12T07:43:35Z","date_published":"2010-01-01T00:00:00Z","quality_controlled":0,"author":[{"first_name":"Bernd","full_name":"Fakler, Bernd","last_name":"Fakler"},{"orcid":"0000-0001-5001-4804","last_name":"Jonas","first_name":"Peter M","id":"353C1B58-F248-11E8-B48F-1D18A9856A87","full_name":"Peter Jonas"}],"publisher":"Springer","publist_id":"2928","status":"public","type":"book_chapter","day":"01","extern":1},{"intvolume":"        18","date_created":"2018-12-11T12:03:39Z","date_updated":"2021-01-12T07:43:51Z","issue":"12","quality_controlled":"1","author":[{"last_name":"Sabeti Aschraf","full_name":"Sabeti Aschraf, M.","first_name":"M."},{"last_name":"Gonano","first_name":"C.","full_name":"Gonano, C."},{"full_name":"Nemecek, E.","first_name":"E.","last_name":"Nemecek"},{"id":"3BC78B60-F248-11E8-B48F-1D18A9856A87","full_name":"Cichocki, Lisa","first_name":"Lisa","last_name":"Cichocki"},{"full_name":"Schueller Weidekamm, C.","first_name":"C.","last_name":"Schueller Weidekamm"}],"publisher":"Springer","date_published":"2010-08-20T00:00:00Z","abstract":[{"text":"Purpose\r\nCalcifying tendinitis is a common condition of the shoulder. In many cases, arthroscopic reduction in the deposit is indicated. The localization of the deposit is sometimes challenging and time-consuming. Pre-operative ultrasound (US)-guided needle placement in the deposit and pre-operative US marking of the deposit at the skin with a ballpoint are described and recommended methods to alleviate the procedure without using ionizing radiation by fluoroscopy.\r\nMethods\r\nIntra-operative sonography of the shoulder is introduced as a new method to localize the calcific deposit with high accuracy. After standard arthroscopic buresectomy, the surgeon performs an ultrasound examination under sterile conditions to localize the deposits. A ventral longitudinal US section is recommended, and the upper arm is rotated until the deposit is visible. Subsequently, perpendicular to the skin at the position of the transducer, a needle is introduced under arthroscopic and ultrasound visualization to puncture the deposit.\r\nResults\r\nThe presence of snow-white crystals at the tip of the needle proves the exact localization. Consecutively, the curettage can be accomplished. Another intra-operative sonography evaluates possible calcific remnants and the tendon structure.\r\nConclusion\r\nThis new technique may alleviate arthroscopic calcific deposit curettage by visualizing the deposit without using ionizing radiation. Additionally, soft tissue damage due to decreased number of punctures to detect the deposit may be achieved. Both factors may contribute to reduced operation time.","lang":"eng"}],"publist_id":"2889","oa_version":"None","day":"20","type":"journal_article","status":"public","scopus_import":1,"user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","month":"08","page":"1792 - 1794","volume":18,"_id":"3498","title":"Intra-operative ultrasound facilitates the localization of the calcific deposit during arthroscopic treatment of calcifying tendinitis","publication":"Knee Surgery, Sports Traumatology, Arthroscopy","year":"2010","publication_status":"published","doi":"10.1007/s00167-010-1227-9","language":[{"iso":"eng"}],"citation":{"mla":"Sabeti Aschraf, M., et al. “Intra-Operative Ultrasound Facilitates the Localization of the Calcific Deposit during Arthroscopic Treatment of Calcifying Tendinitis.” <i>Knee Surgery, Sports Traumatology, Arthroscopy</i>, vol. 18, no. 12, Springer, 2010, pp. 1792–94, doi:<a href=\"https://doi.org/10.1007/s00167-010-1227-9\">10.1007/s00167-010-1227-9</a>.","apa":"Sabeti Aschraf, M., Gonano, C., Nemecek, E., Cichocki, L., &#38; Schueller Weidekamm, C. (2010). Intra-operative ultrasound facilitates the localization of the calcific deposit during arthroscopic treatment of calcifying tendinitis. <i>Knee Surgery, Sports Traumatology, Arthroscopy</i>. Springer. <a href=\"https://doi.org/10.1007/s00167-010-1227-9\">https://doi.org/10.1007/s00167-010-1227-9</a>","ista":"Sabeti Aschraf M, Gonano C, Nemecek E, Cichocki L, Schueller Weidekamm C. 2010. Intra-operative ultrasound facilitates the localization of the calcific deposit during arthroscopic treatment of calcifying tendinitis. Knee Surgery, Sports Traumatology, Arthroscopy. 18(12), 1792–1794.","short":"M. Sabeti Aschraf, C. Gonano, E. Nemecek, L. Cichocki, C. Schueller Weidekamm, Knee Surgery, Sports Traumatology, Arthroscopy 18 (2010) 1792–1794.","chicago":"Sabeti Aschraf, M., C. Gonano, E. Nemecek, Lisa Cichocki, and C. Schueller Weidekamm. “Intra-Operative Ultrasound Facilitates the Localization of the Calcific Deposit during Arthroscopic Treatment of Calcifying Tendinitis.” <i>Knee Surgery, Sports Traumatology, Arthroscopy</i>. Springer, 2010. <a href=\"https://doi.org/10.1007/s00167-010-1227-9\">https://doi.org/10.1007/s00167-010-1227-9</a>.","ama":"Sabeti Aschraf M, Gonano C, Nemecek E, Cichocki L, Schueller Weidekamm C. Intra-operative ultrasound facilitates the localization of the calcific deposit during arthroscopic treatment of calcifying tendinitis. <i>Knee Surgery, Sports Traumatology, Arthroscopy</i>. 2010;18(12):1792-1794. doi:<a href=\"https://doi.org/10.1007/s00167-010-1227-9\">10.1007/s00167-010-1227-9</a>","ieee":"M. Sabeti Aschraf, C. Gonano, E. Nemecek, L. Cichocki, and C. Schueller Weidekamm, “Intra-operative ultrasound facilitates the localization of the calcific deposit during arthroscopic treatment of calcifying tendinitis,” <i>Knee Surgery, Sports Traumatology, Arthroscopy</i>, vol. 18, no. 12. Springer, pp. 1792–1794, 2010."}},{"abstract":[{"lang":"eng","text":"How seizures start is a major question in epilepsy research. Preictal EEG changes occur in both human patients and animal models, but their underlying mechanisms and relationship with seizure initiation remain unknown. Here we demonstrate the existence, in the hippocampal CA1 region, of a preictal state characterized by the progressive and global increase in neuronal activity associated with a widespread buildup of low-amplitude high-frequency activity (HFA) (&gt; 100 Hz) and reduction in system complexity. HFA is generated by the firing of neurons, mainly pyramidal cells, at much lower frequencies. Individual cycles of HFA are generated by the near-synchronous (within similar to 5 ms) firing of small numbers of pyramidal cells. The presence of HFA in the low-calcium model implicates nonsynaptic synchronization; the presence of very similar HFA in the high-potassium model shows that it does not depend on an absence of synaptic transmission. Immediately before seizure onset, CA1 is in a state of high sensitivity in which weak depolarizing or synchronizing perturbations can trigger seizures. Transition to seizure is characterized by a rapid expansion and fusion of the neuronal populations responsible for HFA, associated with a progressive slowing of HFA, leading to a single, massive, hypersynchronous cluster generating the high-amplitude low-frequency activity of the seizure."}],"publist_id":"2848","oa_version":"None","extern":"1","day":"21","status":"public","type":"journal_article","date_created":"2018-12-11T12:03:51Z","intvolume":"        30","date_updated":"2021-01-12T07:44:10Z","issue":"16","quality_controlled":"1","publisher":"Society for Neuroscience","author":[{"full_name":"Jiruska, Premysl","first_name":"Premysl","last_name":"Jiruska"},{"first_name":"Jozsef L","full_name":"Csicsvari, Jozsef L","id":"3FA14672-F248-11E8-B48F-1D18A9856A87","last_name":"Csicsvari","orcid":"0000-0002-5193-4036"},{"last_name":"Powell","first_name":"Andrew","full_name":"Powell, Andrew"},{"last_name":"Fox","first_name":"John","full_name":"Fox, John"},{"last_name":"Chang","first_name":"Wei","full_name":"Chang, Wei"},{"last_name":"Vreugdenhil","first_name":"Martin","full_name":"Vreugdenhil, Martin"},{"full_name":"Li, Xiaoli","first_name":"Xiaoli","last_name":"Li"},{"first_name":"Milan","full_name":"Palus, Milan","last_name":"Palus"},{"last_name":"Bujan","full_name":"Bujan, Alejandro","first_name":"Alejandro"},{"last_name":"Dearden","first_name":"Richard","full_name":"Dearden, Richard"},{"last_name":"Jefferys","first_name":"John","full_name":"Jefferys, John"}],"date_published":"2010-04-21T00:00:00Z","_id":"3538","title":"High-frequency network activity, global increase in neuronal activity, and synchrony expansion precede epileptic seizures in vitro","volume":30,"publication":"Journal of Neuroscience","year":"2010","publication_status":"published","doi":"10.1523/JNEUROSCI.0535-10.2010","language":[{"iso":"eng"}],"oa":1,"citation":{"chicago":"Jiruska, Premysl, Jozsef L Csicsvari, Andrew Powell, John Fox, Wei Chang, Martin Vreugdenhil, Xiaoli Li, et al. “High-Frequency Network Activity, Global Increase in Neuronal Activity, and Synchrony Expansion Precede Epileptic Seizures in Vitro.” <i>Journal of Neuroscience</i>. Society for Neuroscience, 2010. <a href=\"https://doi.org/10.1523/JNEUROSCI.0535-10.2010\">https://doi.org/10.1523/JNEUROSCI.0535-10.2010</a>.","ama":"Jiruska P, Csicsvari JL, Powell A, et al. High-frequency network activity, global increase in neuronal activity, and synchrony expansion precede epileptic seizures in vitro. <i>Journal of Neuroscience</i>. 2010;30(16):5690-5701. doi:<a href=\"https://doi.org/10.1523/JNEUROSCI.0535-10.2010\">10.1523/JNEUROSCI.0535-10.2010</a>","ieee":"P. Jiruska <i>et al.</i>, “High-frequency network activity, global increase in neuronal activity, and synchrony expansion precede epileptic seizures in vitro,” <i>Journal of Neuroscience</i>, vol. 30, no. 16. Society for Neuroscience, pp. 5690–5701, 2010.","mla":"Jiruska, Premysl, et al. “High-Frequency Network Activity, Global Increase in Neuronal Activity, and Synchrony Expansion Precede Epileptic Seizures in Vitro.” <i>Journal of Neuroscience</i>, vol. 30, no. 16, Society for Neuroscience, 2010, pp. 5690–701, doi:<a href=\"https://doi.org/10.1523/JNEUROSCI.0535-10.2010\">10.1523/JNEUROSCI.0535-10.2010</a>.","apa":"Jiruska, P., Csicsvari, J. L., Powell, A., Fox, J., Chang, W., Vreugdenhil, M., … Jefferys, J. (2010). High-frequency network activity, global increase in neuronal activity, and synchrony expansion precede epileptic seizures in vitro. <i>Journal of Neuroscience</i>. Society for Neuroscience. <a href=\"https://doi.org/10.1523/JNEUROSCI.0535-10.2010\">https://doi.org/10.1523/JNEUROSCI.0535-10.2010</a>","short":"P. Jiruska, J.L. Csicsvari, A. Powell, J. Fox, W. Chang, M. Vreugdenhil, X. Li, M. Palus, A. Bujan, R. Dearden, J. Jefferys, Journal of Neuroscience 30 (2010) 5690–5701.","ista":"Jiruska P, Csicsvari JL, Powell A, Fox J, Chang W, Vreugdenhil M, Li X, Palus M, Bujan A, Dearden R, Jefferys J. 2010. High-frequency network activity, global increase in neuronal activity, and synchrony expansion precede epileptic seizures in vitro. Journal of Neuroscience. 30(16), 5690–5701."},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","month":"04","main_file_link":[{"url":"http://www.jneurosci.org/content/30/16/5690","open_access":"1"}],"page":"5690 - 5701"},{"issue":"Part 5","intvolume":"       546","date_created":"2018-12-11T12:04:08Z","date_updated":"2021-01-12T07:44:31Z","date_published":"2010-01-01T00:00:00Z","author":[{"first_name":"Lara","full_name":"Carvalho, Lara","last_name":"Carvalho"},{"orcid":"0000-0002-0912-4566","last_name":"Heisenberg","id":"39427864-F248-11E8-B48F-1D18A9856A87","first_name":"Carl-Philipp J","full_name":"Heisenberg, Carl-Philipp J"}],"publisher":"Springer","publist_id":"2791","oa_version":"None","abstract":[{"text":"The zebrafish is a favorite model organism to study tissue morphogenesis during development at a subcellular level. This largely results from the fact that zebrafish embryos are transparent and thus accessible to various imaging techniques, such as confocal and two-photon excitation (2PE) microscopy. In particular, 2PE microscopy has been shown to be useful for imaging deep cell layers within the embryo and following tissue morphogenesis over long periods. This chapter describes how to use 2PE microscopy to study morphogenetic movements during early zebrafish embryonic development, providing a general blueprint for its use in zebrafish.","lang":"eng"}],"type":"journal_article","status":"public","extern":"1","day":"01","month":"01","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","page":"273 - 287","year":"2010","publication_status":"published","doi":"10.1007/978-1-60327-977-2_17","language":[{"iso":"eng"}],"publication":"Methods in Molecular Biology","_id":"3592","volume":546,"article_processing_charge":"No","title":"Imaging zebrafish embryos by two-photon excitation time-lapse microscopy","citation":{"mla":"Carvalho, Lara, and Carl-Philipp J. Heisenberg. “Imaging Zebrafish Embryos by Two-Photon Excitation Time-Lapse Microscopy.” <i>Methods in Molecular Biology</i>, vol. 546, no. Part 5, Springer, 2010, pp. 273–87, doi:<a href=\"https://doi.org/10.1007/978-1-60327-977-2_17\">10.1007/978-1-60327-977-2_17</a>.","apa":"Carvalho, L., &#38; Heisenberg, C.-P. J. (2010). Imaging zebrafish embryos by two-photon excitation time-lapse microscopy. <i>Methods in Molecular Biology</i>. Springer. <a href=\"https://doi.org/10.1007/978-1-60327-977-2_17\">https://doi.org/10.1007/978-1-60327-977-2_17</a>","ista":"Carvalho L, Heisenberg C-PJ. 2010. Imaging zebrafish embryos by two-photon excitation time-lapse microscopy. Methods in Molecular Biology. 546(Part 5), 273–287.","short":"L. Carvalho, C.-P.J. Heisenberg, Methods in Molecular Biology 546 (2010) 273–287.","chicago":"Carvalho, Lara, and Carl-Philipp J Heisenberg. “Imaging Zebrafish Embryos by Two-Photon Excitation Time-Lapse Microscopy.” <i>Methods in Molecular Biology</i>. Springer, 2010. <a href=\"https://doi.org/10.1007/978-1-60327-977-2_17\">https://doi.org/10.1007/978-1-60327-977-2_17</a>.","ama":"Carvalho L, Heisenberg C-PJ. Imaging zebrafish embryos by two-photon excitation time-lapse microscopy. <i>Methods in Molecular Biology</i>. 2010;546(Part 5):273-287. doi:<a href=\"https://doi.org/10.1007/978-1-60327-977-2_17\">10.1007/978-1-60327-977-2_17</a>","ieee":"L. Carvalho and C.-P. J. Heisenberg, “Imaging zebrafish embryos by two-photon excitation time-lapse microscopy,” <i>Methods in Molecular Biology</i>, vol. 546, no. Part 5. Springer, pp. 273–287, 2010."}}]