[{"author":[{"first_name":"Philip","last_name":"Grech","full_name":"Grech, Philip"},{"id":"4AFD0470-F248-11E8-B48F-1D18A9856A87","first_name":"Robert","last_name":"Seiringer","full_name":"Robert Seiringer","orcid":"0000-0002-6781-0521"}],"doi":"10.1007/s00220-013-1736-8","citation":{"ama":"Grech P, Seiringer R. The excitation spectrum for weakly interacting Bosons in a trap. <i>Communications in Mathematical Physics</i>. 2013;322(2):559-591. doi:<a href=\"https://doi.org/10.1007/s00220-013-1736-8\">10.1007/s00220-013-1736-8</a>","apa":"Grech, P., &#38; Seiringer, R. (2013). The excitation spectrum for weakly interacting Bosons in a trap. <i>Communications in Mathematical Physics</i>. Springer. <a href=\"https://doi.org/10.1007/s00220-013-1736-8\">https://doi.org/10.1007/s00220-013-1736-8</a>","short":"P. Grech, R. Seiringer, Communications in Mathematical Physics 322 (2013) 559–591.","chicago":"Grech, Philip, and Robert Seiringer. “The Excitation Spectrum for Weakly Interacting Bosons in a Trap.” <i>Communications in Mathematical Physics</i>. Springer, 2013. <a href=\"https://doi.org/10.1007/s00220-013-1736-8\">https://doi.org/10.1007/s00220-013-1736-8</a>.","ieee":"P. Grech and R. Seiringer, “The excitation spectrum for weakly interacting Bosons in a trap,” <i>Communications in Mathematical Physics</i>, vol. 322, no. 2. Springer, pp. 559–591, 2013.","ista":"Grech P, Seiringer R. 2013. The excitation spectrum for weakly interacting Bosons in a trap. Communications in Mathematical Physics. 322(2), 559–591.","mla":"Grech, Philip, and Robert Seiringer. “The Excitation Spectrum for Weakly Interacting Bosons in a Trap.” <i>Communications in Mathematical Physics</i>, vol. 322, no. 2, Springer, 2013, pp. 559–91, doi:<a href=\"https://doi.org/10.1007/s00220-013-1736-8\">10.1007/s00220-013-1736-8</a>."},"date_created":"2018-12-11T11:57:29Z","quality_controlled":0,"issue":"2","_id":"2408","type":"journal_article","extern":1,"publication":"Communications in Mathematical Physics","volume":322,"title":"The excitation spectrum for weakly interacting Bosons in a trap","intvolume":"       322","status":"public","day":"01","year":"2013","page":"559 - 591","main_file_link":[{"open_access":"1","url":"http://arxiv.org/abs/1205.5259"}],"publication_status":"published","publisher":"Springer","date_updated":"2021-01-12T06:57:18Z","publist_id":"4518","oa":1,"abstract":[{"lang":"eng","text":"We investigate the low-energy excitation spectrum of a Bose gas confined in a trap, with weak long-range repulsive interactions. In particular, we prove that the spectrum can be described in terms of the eigenvalues of an effective one-particle operator, as predicted by the Bogoliubov approximation."}],"month":"09","date_published":"2013-09-01T00:00:00Z"},{"abstract":[{"text":"Here, we describe a novel virulent bacteriophage that infects Bacillus weihenstephanensis, isolated from soil in Austria. It is the first phage to be discovered that infects this species. Here, we present the complete genome sequence of this podovirus. ","lang":"eng"}],"ddc":["576"],"oa":1,"file":[{"date_created":"2018-12-12T10:17:36Z","access_level":"open_access","file_id":"5291","file_name":"IST-2015-398-v1+1_Genome_Announc.-2013-Redondo-.pdf","relation":"main_file","content_type":"application/pdf","creator":"system","file_size":130026,"checksum":"0751ec74b695567e0cdf02aaf9c26829","date_updated":"2020-07-14T12:45:40Z"}],"year":"2013","language":[{"iso":"eng"}],"has_accepted_license":"1","intvolume":"         1","quality_controlled":"1","citation":{"mla":"Fernandes Redondo, Rodrigo A., et al. “Complete Genome Sequence of the Novel Phage MG-B1 Infecting Bacillus Weihenstephanensis.” <i>Genome Announcements</i>, vol. 1, no. 3, American Society for Microbiology, 2013, doi:<a href=\"https://doi.org/10.1128/genomeA.00216-13\">10.1128/genomeA.00216-13</a>.","ista":"Fernandes Redondo RA, Kupczok A, Stift G, Bollback JP. 2013. Complete genome sequence of the novel phage MG-B1 infecting bacillus weihenstephanensis. Genome Announcements. 1(3).","ieee":"R. A. Fernandes Redondo, A. Kupczok, G. Stift, and J. P. Bollback, “Complete genome sequence of the novel phage MG-B1 infecting bacillus weihenstephanensis,” <i>Genome Announcements</i>, vol. 1, no. 3. American Society for Microbiology, 2013.","chicago":"Fernandes Redondo, Rodrigo A, Anne Kupczok, Gertraud Stift, and Jonathan P Bollback. “Complete Genome Sequence of the Novel Phage MG-B1 Infecting Bacillus Weihenstephanensis.” <i>Genome Announcements</i>. American Society for Microbiology, 2013. <a href=\"https://doi.org/10.1128/genomeA.00216-13\">https://doi.org/10.1128/genomeA.00216-13</a>.","short":"R.A. Fernandes Redondo, A. Kupczok, G. Stift, J.P. Bollback, Genome Announcements 1 (2013).","apa":"Fernandes Redondo, R. A., Kupczok, A., Stift, G., &#38; Bollback, J. P. (2013). Complete genome sequence of the novel phage MG-B1 infecting bacillus weihenstephanensis. <i>Genome Announcements</i>. American Society for Microbiology. <a href=\"https://doi.org/10.1128/genomeA.00216-13\">https://doi.org/10.1128/genomeA.00216-13</a>","ama":"Fernandes Redondo RA, Kupczok A, Stift G, Bollback JP. Complete genome sequence of the novel phage MG-B1 infecting bacillus weihenstephanensis. <i>Genome Announcements</i>. 2013;1(3). doi:<a href=\"https://doi.org/10.1128/genomeA.00216-13\">10.1128/genomeA.00216-13</a>"},"doi":"10.1128/genomeA.00216-13","date_published":"2013-06-13T00:00:00Z","month":"06","publication_status":"published","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2021-01-12T06:57:19Z","publist_id":"4516","publisher":"American Society for Microbiology","scopus_import":1,"day":"13","volume":1,"title":"Complete genome sequence of the novel phage MG-B1 infecting bacillus weihenstephanensis","status":"public","oa_version":"Published Version","date_created":"2018-12-11T11:57:30Z","pubrep_id":"398","publication":"Genome Announcements","file_date_updated":"2020-07-14T12:45:40Z","issue":"3","_id":"2410","type":"journal_article","author":[{"full_name":"Fernandes Redondo, Rodrigo A","orcid":"0000-0002-5837-2793","last_name":"Fernandes Redondo","id":"409D5C96-F248-11E8-B48F-1D18A9856A87","first_name":"Rodrigo A"},{"full_name":"Kupczok, Anne","last_name":"Kupczok","first_name":"Anne","id":"2BB22BC2-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Stift, Gertraud","last_name":"Stift","first_name":"Gertraud","id":"2DB195CA-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Bollback, Jonathan P","orcid":"0000-0002-4624-4612","last_name":"Bollback","first_name":"Jonathan P","id":"2C6FA9CC-F248-11E8-B48F-1D18A9856A87"}],"department":[{"_id":"JoBo"},{"_id":"LifeSc"}]},{"status":"public","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"title":"Probabilistic models for CRISPR spacer content evolution ","volume":13,"day":"26","department":[{"_id":"JoBo"}],"author":[{"last_name":"Kupczok","id":"2BB22BC2-F248-11E8-B48F-1D18A9856A87","first_name":"Anne","full_name":"Kupczok, Anne"},{"full_name":"Bollback, Jonathan P","orcid":"0000-0002-4624-4612","id":"2C6FA9CC-F248-11E8-B48F-1D18A9856A87","first_name":"Jonathan P","last_name":"Bollback"}],"publication":"BMC Evolutionary Biology","file_date_updated":"2020-07-14T12:45:40Z","issue":"1","_id":"2412","type":"journal_article","date_created":"2018-12-11T11:57:31Z","pubrep_id":"397","oa_version":"Published Version","date_updated":"2021-01-12T06:57:20Z","publist_id":"4514","publisher":"BioMed Central","publication_status":"published","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2013-02-26T00:00:00Z","month":"02","scopus_import":1,"intvolume":"        13","has_accepted_license":"1","language":[{"iso":"eng"}],"year":"2013","quality_controlled":"1","citation":{"short":"A. Kupczok, J.P. Bollback, BMC Evolutionary Biology 13 (2013) 54–54.","chicago":"Kupczok, Anne, and Jonathan P Bollback. “Probabilistic Models for CRISPR Spacer Content Evolution .” <i>BMC Evolutionary Biology</i>. BioMed Central, 2013. <a href=\"https://doi.org/10.1186/1471-2148-13-54\">https://doi.org/10.1186/1471-2148-13-54</a>.","apa":"Kupczok, A., &#38; Bollback, J. P. (2013). Probabilistic models for CRISPR spacer content evolution . <i>BMC Evolutionary Biology</i>. BioMed Central. <a href=\"https://doi.org/10.1186/1471-2148-13-54\">https://doi.org/10.1186/1471-2148-13-54</a>","mla":"Kupczok, Anne, and Jonathan P. Bollback. “Probabilistic Models for CRISPR Spacer Content Evolution .” <i>BMC Evolutionary Biology</i>, vol. 13, no. 1, BioMed Central, 2013, pp. 54–54, doi:<a href=\"https://doi.org/10.1186/1471-2148-13-54\">10.1186/1471-2148-13-54</a>.","ieee":"A. Kupczok and J. P. Bollback, “Probabilistic models for CRISPR spacer content evolution ,” <i>BMC Evolutionary Biology</i>, vol. 13, no. 1. BioMed Central, pp. 54–54, 2013.","ista":"Kupczok A, Bollback JP. 2013. Probabilistic models for CRISPR spacer content evolution . BMC Evolutionary Biology. 13(1), 54–54.","ama":"Kupczok A, Bollback JP. Probabilistic models for CRISPR spacer content evolution . <i>BMC Evolutionary Biology</i>. 2013;13(1):54-54. doi:<a href=\"https://doi.org/10.1186/1471-2148-13-54\">10.1186/1471-2148-13-54</a>"},"doi":"10.1186/1471-2148-13-54","file":[{"file_name":"IST-2015-397-v1+1_1471-2148-13-54.pdf","relation":"main_file","content_type":"application/pdf","date_created":"2018-12-12T10:17:15Z","access_level":"open_access","file_id":"5268","date_updated":"2020-07-14T12:45:40Z","creator":"system","file_size":518729,"checksum":"029c7e0b198c19312b66ecce3cabb22f"}],"abstract":[{"text":"Background: The CRISPR/Cas system is known to act as an adaptive and heritable immune system in Eubacteria and Archaea. Immunity is encoded in an array of spacer sequences. Each spacer can provide specific immunity to invasive elements that carry the same or a similar sequence. Even in closely related strains, spacer content is very dynamic and evolves quickly. Standard models of nucleotide evolutioncannot be applied to quantify its rate of change since processes other than single nucleotide changes determine its evolution.Methods We present probabilistic models that are specific for spacer content evolution. They account for the different processes of insertion and deletion. Insertions can be constrained to occur on one end only or are allowed to occur throughout the array. One deletion event can affect one spacer or a whole fragment of adjacent spacers. Parameters of the underlying models are estimated for a pair of arrays by maximum likelihood using explicit ancestor enumeration.Results Simulations show that parameters are well estimated on average under the models presented here. There is a bias in the rate estimation when including fragment deletions. The models also estimate times between pairs of strains. But with increasing time, spacer overlap goes to zero, and thus there is an upper bound on the distance that can be estimated. Spacer content similarities are displayed in a distance based phylogeny using the estimated times.We use the presented models to analyze different Yersinia pestis data sets and find that the results among them are largely congruent. The models also capture the variation in diversity of spacers among the data sets. A comparison of spacer-based phylogenies and Cas gene phylogenies shows that they resolve very different time scales for this data set.Conclusions The simulations and data analyses show that the presented models are useful for quantifying spacer content evolution and for displaying spacer content similarities of closely related strains in a phylogeny. This allows for comparisons of different CRISPR arrays or for comparisons between CRISPR arrays and nucleotide substitution rates.","lang":"eng"}],"ddc":["576"],"oa":1,"page":"54 - 54"},{"editor":[{"last_name":"Meyer","first_name":"Misha","full_name":"Meyer, Misha"},{"last_name":"Pesenson","first_name":"Z.","full_name":"Pesenson, Z."}],"scopus_import":1,"alternative_title":["Reviews of Nonlinear Dynamics and Complexity"],"date_published":"2013-08-01T00:00:00Z","month":"08","abstract":[{"text":"Progress in understanding the global brain dynamics has remained slow to date in large part because of the highly multiscale nature of brain activity. Indeed, normal brain dynamics is characterized by complex interactions between multiple levels: from the microscopic scale of single neurons to the mesoscopic level of local groups of neurons, and finally to the macroscopic level of the whole brain. Among the most difficult tasks are those of identifying which scales are significant for a given particular function and describing how the scales affect each other. It is important to realize that the scales of time and space are linked together, or even intertwined, and that causal inference is far more ambiguous between than within levels. We approach this problem from the perspective of our recent work on simultaneous recording from micro- and macroelectrodes in the human brain. We propose a physiological description of these multilevel interactions, based on phase–amplitude coupling of neuronal oscillations that operate at multiple frequencies and on different spatial scales. Specifically, the amplitude of the oscillations on a particular spatial scale is modulated by phasic variations in neuronal excitability induced by lower frequency oscillations that emerge on a larger spatial scale. Following this general principle, it is possible to scale up or scale down the multiscale brain dynamics. It is expected that large-scale network oscillations in the low-frequency range, mediating downward effects, may play an important role in attention and consciousness.","lang":"eng"}],"date_updated":"2021-01-12T06:57:20Z","publist_id":"4513","publisher":"Wiley-VCH","publication_status":"published","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","publication":"Multiscale Analysis and Nonlinear Dynamics: From Genes to the Brain","_id":"2413","type":"book_chapter","quality_controlled":"1","date_created":"2018-12-11T11:57:31Z","oa_version":"None","doi":"10.1002/9783527671632.ch08","citation":{"ama":"Valderrama M, Botella Soler V, Le Van Quyen M. Neuronal oscillations scale up and scale down the brain dynamics . In: Meyer M, Pesenson Z, eds. <i>Multiscale Analysis and Nonlinear Dynamics: From Genes to the Brain</i>. Wiley-VCH; 2013. doi:<a href=\"https://doi.org/10.1002/9783527671632.ch08\">10.1002/9783527671632.ch08</a>","chicago":"Valderrama, Mario, Vicente Botella Soler, and Michel Le Van Quyen. “Neuronal Oscillations Scale up and Scale down the Brain Dynamics .” In <i>Multiscale Analysis and Nonlinear Dynamics: From Genes to the Brain</i>, edited by Misha Meyer and Z. Pesenson. Wiley-VCH, 2013. <a href=\"https://doi.org/10.1002/9783527671632.ch08\">https://doi.org/10.1002/9783527671632.ch08</a>.","short":"M. Valderrama, V. Botella Soler, M. Le Van Quyen, in:, M. Meyer, Z. Pesenson (Eds.), Multiscale Analysis and Nonlinear Dynamics: From Genes to the Brain, Wiley-VCH, 2013.","apa":"Valderrama, M., Botella Soler, V., &#38; Le Van Quyen, M. (2013). Neuronal oscillations scale up and scale down the brain dynamics . In M. Meyer &#38; Z. Pesenson (Eds.), <i>Multiscale Analysis and Nonlinear Dynamics: From Genes to the Brain</i>. Wiley-VCH. <a href=\"https://doi.org/10.1002/9783527671632.ch08\">https://doi.org/10.1002/9783527671632.ch08</a>","mla":"Valderrama, Mario, et al. “Neuronal Oscillations Scale up and Scale down the Brain Dynamics .” <i>Multiscale Analysis and Nonlinear Dynamics: From Genes to the Brain</i>, edited by Misha Meyer and Z. Pesenson, Wiley-VCH, 2013, doi:<a href=\"https://doi.org/10.1002/9783527671632.ch08\">10.1002/9783527671632.ch08</a>.","ieee":"M. Valderrama, V. Botella Soler, and M. Le Van Quyen, “Neuronal oscillations scale up and scale down the brain dynamics ,” in <i>Multiscale Analysis and Nonlinear Dynamics: From Genes to the Brain</i>, M. Meyer and Z. Pesenson, Eds. Wiley-VCH, 2013.","ista":"Valderrama M, Botella Soler V, Le Van Quyen M. 2013.Neuronal oscillations scale up and scale down the brain dynamics . In: Multiscale Analysis and Nonlinear Dynamics: From Genes to the Brain. Reviews of Nonlinear Dynamics and Complexity, ."},"department":[{"_id":"GaTk"}],"author":[{"first_name":"Mario","last_name":"Valderrama","full_name":"Valderrama, Mario"},{"id":"421234E8-F248-11E8-B48F-1D18A9856A87","first_name":"Vicente","last_name":"Botella Soler","orcid":"0000-0002-8790-1914","full_name":"Botella Soler, Vicente"},{"first_name":"Michel","last_name":"Le Van Quyen","full_name":"Le Van Quyen, Michel"}],"publication_identifier":{"eisbn":["9783527671632"],"isbn":["9783527411986 "]},"language":[{"iso":"eng"}],"year":"2013","day":"01","status":"public","title":"Neuronal oscillations scale up and scale down the brain dynamics "},{"file":[{"file_size":365548,"checksum":"70c70ca5487faba82262c63e1b678a27","creator":"system","date_updated":"2020-07-14T12:45:40Z","file_id":"5158","access_level":"open_access","date_created":"2018-12-12T10:15:37Z","content_type":"application/pdf","file_name":"IST-2014-199-v1+1_cav2013-final.pdf","relation":"main_file"}],"ddc":["000","004"],"oa":1,"abstract":[{"lang":"eng","text":"We develop program synthesis techniques that can help programmers fix concurrency-related bugs. We make two new contributions to synthesis for concurrency, the first improving the efficiency of the synthesized code, and the second improving the efficiency of the synthesis procedure itself. The first contribution is to have the synthesis procedure explore a variety of (sequential) semantics-preserving program transformations. Classically, only one such transformation has been considered, namely, the insertion of synchronization primitives (such as locks). Based on common manual bug-fixing techniques used by Linux device-driver developers, we explore additional, more efficient transformations, such as the reordering of independent instructions. The second contribution is to speed up the counterexample-guided removal of concurrency bugs within the synthesis procedure by considering partial-order traces (instead of linear traces) as counterexamples. A partial-order error trace represents a set of linear (interleaved) traces of a concurrent program all of which lead to the same error. By eliminating a partial-order error trace, we eliminate in a single iteration of the synthesis procedure all linearizations of the partial-order trace. We evaluated our techniques on several simplified examples of real concurrency bugs that occurred in Linux device drivers."}],"page":"951 - 967","alternative_title":["LNCS"],"language":[{"iso":"eng"}],"year":"2013","intvolume":"      8044","has_accepted_license":"1","citation":{"mla":"Cerny, Pavol, et al. <i>Efficient Synthesis for Concurrency by Semantics-Preserving Transformations</i>. Vol. 8044, Springer, 2013, pp. 951–67, doi:<a href=\"https://doi.org/10.1007/978-3-642-39799-8_68\">10.1007/978-3-642-39799-8_68</a>.","ieee":"P. Cerny, T. A. Henzinger, A. Radhakrishna, L. Ryzhyk, and T. Tarrach, “Efficient synthesis for concurrency by semantics-preserving transformations,” presented at the CAV: Computer Aided Verification, St. Petersburg, Russia, 2013, vol. 8044, pp. 951–967.","ista":"Cerny P, Henzinger TA, Radhakrishna A, Ryzhyk L, Tarrach T. 2013. Efficient synthesis for concurrency by semantics-preserving transformations. CAV: Computer Aided Verification, LNCS, vol. 8044, 951–967.","short":"P. Cerny, T.A. Henzinger, A. Radhakrishna, L. Ryzhyk, T. Tarrach, in:, Springer, 2013, pp. 951–967.","chicago":"Cerny, Pavol, Thomas A Henzinger, Arjun Radhakrishna, Leonid Ryzhyk, and Thorsten Tarrach. “Efficient Synthesis for Concurrency by Semantics-Preserving Transformations,” 8044:951–67. Springer, 2013. <a href=\"https://doi.org/10.1007/978-3-642-39799-8_68\">https://doi.org/10.1007/978-3-642-39799-8_68</a>.","apa":"Cerny, P., Henzinger, T. A., Radhakrishna, A., Ryzhyk, L., &#38; Tarrach, T. (2013). Efficient synthesis for concurrency by semantics-preserving transformations (Vol. 8044, pp. 951–967). Presented at the CAV: Computer Aided Verification, St. Petersburg, Russia: Springer. <a href=\"https://doi.org/10.1007/978-3-642-39799-8_68\">https://doi.org/10.1007/978-3-642-39799-8_68</a>","ama":"Cerny P, Henzinger TA, Radhakrishna A, Ryzhyk L, Tarrach T. Efficient synthesis for concurrency by semantics-preserving transformations. In: Vol 8044. Springer; 2013:951-967. doi:<a href=\"https://doi.org/10.1007/978-3-642-39799-8_68\">10.1007/978-3-642-39799-8_68</a>"},"doi":"10.1007/978-3-642-39799-8_68","quality_controlled":"1","ec_funded":1,"conference":{"name":"CAV: Computer Aided Verification","start_date":"2013-07-13","end_date":"2013-07-19","location":"St. Petersburg, Russia"},"related_material":{"record":[{"status":"public","id":"1130","relation":"dissertation_contains"}]},"month":"07","date_published":"2013-07-01T00:00:00Z","publisher":"Springer","date_updated":"2023-09-07T11:57:01Z","publist_id":"4458","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","scopus_import":1,"day":"01","status":"public","volume":8044,"title":"Efficient synthesis for concurrency by semantics-preserving transformations","type":"conference","_id":"2445","file_date_updated":"2020-07-14T12:45:40Z","project":[{"_id":"25EE3708-B435-11E9-9278-68D0E5697425","name":"Quantitative Reactive Modeling","call_identifier":"FP7","grant_number":"267989"},{"call_identifier":"FWF","grant_number":"S 11407_N23","_id":"25832EC2-B435-11E9-9278-68D0E5697425","name":"Rigorous Systems Engineering"}],"pubrep_id":"199","date_created":"2018-12-11T11:57:42Z","oa_version":"Submitted Version","department":[{"_id":"ToHe"}],"author":[{"full_name":"Cerny, Pavol","last_name":"Cerny","first_name":"Pavol","id":"4DCBEFFE-F248-11E8-B48F-1D18A9856A87"},{"id":"40876CD8-F248-11E8-B48F-1D18A9856A87","first_name":"Thomas A","last_name":"Henzinger","orcid":"0000−0002−2985−7724","full_name":"Henzinger, Thomas A"},{"last_name":"Radhakrishna","first_name":"Arjun","id":"3B51CAC4-F248-11E8-B48F-1D18A9856A87","full_name":"Radhakrishna, Arjun"},{"full_name":"Ryzhyk, Leonid","first_name":"Leonid","last_name":"Ryzhyk"},{"full_name":"Tarrach, Thorsten","orcid":"0000-0003-4409-8487","id":"3D6E8F2C-F248-11E8-B48F-1D18A9856A87","first_name":"Thorsten","last_name":"Tarrach"}]},{"page":"559 - 575","alternative_title":["LNCS"],"external_id":{"arxiv":["1304.5281"]},"oa":1,"abstract":[{"text":"The model-checking problem for probabilistic systems crucially relies on the translation of LTL to deterministic Rabin automata (DRW). Our recent Safraless translation [KE12, GKE12] for the LTL(F,G) fragment produces smaller automata as compared to the traditional approach. In this work, instead of DRW we consider deterministic automata with acceptance condition given as disjunction of generalized Rabin pairs (DGRW). The Safraless translation of LTL(F,G) formulas to DGRW results in smaller automata as compared to DRW. We present algorithms for probabilistic model-checking as well as game solving for DGRW conditions. Our new algorithms lead to improvement both in terms of theoretical bounds as well as practical evaluation. We compare PRISM with and without our new translation, and show that the new translation leads to significant improvements.","lang":"eng"}],"conference":{"start_date":"2013-07-13","end_date":"2013-07-19","location":"St. Petersburg, Russia","name":"CAV: Computer Aided Verification"},"doi":"10.1007/978-3-642-39799-8_37","citation":{"ama":"Chatterjee K, Gaiser A, Kretinsky J. Automata with generalized Rabin pairs for probabilistic model checking and LTL synthesis. 2013;8044:559-575. doi:<a href=\"https://doi.org/10.1007/978-3-642-39799-8_37\">10.1007/978-3-642-39799-8_37</a>","ieee":"K. Chatterjee, A. Gaiser, and J. Kretinsky, “Automata with generalized Rabin pairs for probabilistic model checking and LTL synthesis,” vol. 8044. Springer, pp. 559–575, 2013.","ista":"Chatterjee K, Gaiser A, Kretinsky J. 2013. Automata with generalized Rabin pairs for probabilistic model checking and LTL synthesis. 8044, 559–575.","mla":"Chatterjee, Krishnendu, et al. <i>Automata with Generalized Rabin Pairs for Probabilistic Model Checking and LTL Synthesis</i>. Vol. 8044, Springer, 2013, pp. 559–75, doi:<a href=\"https://doi.org/10.1007/978-3-642-39799-8_37\">10.1007/978-3-642-39799-8_37</a>.","apa":"Chatterjee, K., Gaiser, A., &#38; Kretinsky, J. (2013). Automata with generalized Rabin pairs for probabilistic model checking and LTL synthesis. Presented at the CAV: Computer Aided Verification, St. Petersburg, Russia: Springer. <a href=\"https://doi.org/10.1007/978-3-642-39799-8_37\">https://doi.org/10.1007/978-3-642-39799-8_37</a>","short":"K. Chatterjee, A. Gaiser, J. Kretinsky, 8044 (2013) 559–575.","chicago":"Chatterjee, Krishnendu, Andreas Gaiser, and Jan Kretinsky. “Automata with Generalized Rabin Pairs for Probabilistic Model Checking and LTL Synthesis.” Lecture Notes in Computer Science. Springer, 2013. <a href=\"https://doi.org/10.1007/978-3-642-39799-8_37\">https://doi.org/10.1007/978-3-642-39799-8_37</a>."},"ec_funded":1,"quality_controlled":"1","arxiv":1,"intvolume":"      8044","year":"2013","language":[{"iso":"eng"}],"scopus_import":1,"series_title":"Lecture Notes in Computer Science","main_file_link":[{"url":"http://arxiv.org/abs/1304.5281","open_access":"1"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","publisher":"Springer","date_updated":"2020-08-11T10:09:47Z","publist_id":"4457","date_published":"2013-07-01T00:00:00Z","month":"07","author":[{"last_name":"Chatterjee","first_name":"Krishnendu","id":"2E5DCA20-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-4561-241X","full_name":"Chatterjee, Krishnendu"},{"full_name":"Gaiser, Andreas","first_name":"Andreas","last_name":"Gaiser"},{"orcid":"0000-0002-8122-2881","full_name":"Kretinsky, Jan","last_name":"Kretinsky","id":"44CEF464-F248-11E8-B48F-1D18A9856A87","first_name":"Jan"}],"department":[{"_id":"KrCh"}],"project":[{"name":"Modern Graph Algorithmic Techniques in Formal Verification","_id":"2584A770-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","grant_number":"P 23499-N23"},{"_id":"25863FF4-B435-11E9-9278-68D0E5697425","name":"Game Theory","grant_number":"S11407","call_identifier":"FWF"},{"call_identifier":"FP7","grant_number":"279307","_id":"2581B60A-B435-11E9-9278-68D0E5697425","name":"Quantitative Graph Games: Theory and Applications"},{"_id":"2587B514-B435-11E9-9278-68D0E5697425","name":"Microsoft Research Faculty Fellowship"}],"oa_version":"Preprint","date_created":"2018-12-11T11:57:42Z","_id":"2446","type":"conference","title":"Automata with generalized Rabin pairs for probabilistic model checking and LTL synthesis","volume":8044,"status":"public","day":"01"},{"language":[{"iso":"eng"}],"year":"2013","intvolume":"      8044","has_accepted_license":"1","doi":"10.1007/978-3-642-39799-8_54","citation":{"apa":"Piskac, R., Wies, T., &#38; Zufferey, D. (2013). Automating separation logic using SMT. Presented at the CAV: Computer Aided Verification, St. Petersburg, Russia: Springer. <a href=\"https://doi.org/10.1007/978-3-642-39799-8_54\">https://doi.org/10.1007/978-3-642-39799-8_54</a>","short":"R. Piskac, T. Wies, D. Zufferey, 8044 (2013) 773–789.","chicago":"Piskac, Ruzica, Thomas Wies, and Damien Zufferey. “Automating Separation Logic Using SMT.” Lecture Notes in Computer Science. Springer, 2013. <a href=\"https://doi.org/10.1007/978-3-642-39799-8_54\">https://doi.org/10.1007/978-3-642-39799-8_54</a>.","ista":"Piskac R, Wies T, Zufferey D. 2013. Automating separation logic using SMT. 8044, 773–789.","ieee":"R. Piskac, T. Wies, and D. Zufferey, “Automating separation logic using SMT,” vol. 8044. Springer, pp. 773–789, 2013.","mla":"Piskac, Ruzica, et al. <i>Automating Separation Logic Using SMT</i>. Vol. 8044, Springer, 2013, pp. 773–89, doi:<a href=\"https://doi.org/10.1007/978-3-642-39799-8_54\">10.1007/978-3-642-39799-8_54</a>.","ama":"Piskac R, Wies T, Zufferey D. Automating separation logic using SMT. 2013;8044:773-789. doi:<a href=\"https://doi.org/10.1007/978-3-642-39799-8_54\">10.1007/978-3-642-39799-8_54</a>"},"quality_controlled":"1","conference":{"name":"CAV: Computer Aided Verification","start_date":"2013-07-13","end_date":"2013-07-19","location":"St. Petersburg, Russia"},"file":[{"file_id":"7859","access_level":"open_access","date_created":"2020-05-15T11:13:01Z","content_type":"application/pdf","relation":"main_file","file_name":"2013_CAV_Piskac.pdf","checksum":"2e866932ab688f47ecd504acb4d5c7d4","file_size":309182,"creator":"dernst","date_updated":"2020-07-14T12:45:41Z"}],"oa":1,"ddc":["000"],"abstract":[{"text":"Separation logic (SL) has gained widespread popularity because of its ability to succinctly express complex invariants of a program’s heap configurations. Several specialized provers have been developed for decidable SL fragments. However, these provers cannot be easily extended or combined with solvers for other theories that are important in program verification, e.g., linear arithmetic. In this paper, we present a reduction of decidable SL fragments to a decidable first-order theory that fits well into the satisfiability modulo theories (SMT) framework. We show how to use this reduction to automate satisfiability, entailment, frame inference, and abduction problems for separation logic using SMT solvers. Our approach provides a simple method of integrating separation logic into existing verification tools that provide SMT backends, and an elegant way of combining SL fragments with other decidable first-order theories. We implemented this approach in a verification tool and applied it to heap-manipulating programs whose verification involves reasoning in theory combinations.\r\n","lang":"eng"}],"alternative_title":["LNCS"],"page":"773 - 789","day":"01","status":"public","volume":8044,"title":"Automating separation logic using SMT","_id":"2447","type":"conference","article_processing_charge":"No","file_date_updated":"2020-07-14T12:45:41Z","oa_version":"Submitted Version","date_created":"2018-12-11T11:57:43Z","department":[{"_id":"ToHe"}],"author":[{"last_name":"Piskac","first_name":"Ruzica","full_name":"Piskac, Ruzica"},{"full_name":"Wies, Thomas","first_name":"Thomas","id":"447BFB88-F248-11E8-B48F-1D18A9856A87","last_name":"Wies"},{"last_name":"Zufferey","first_name":"Damien","id":"4397AC76-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-3197-8736","full_name":"Zufferey, Damien"}],"date_published":"2013-07-01T00:00:00Z","month":"07","publisher":"Springer","date_updated":"2020-08-11T10:09:47Z","publist_id":"4456","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","series_title":"Lecture Notes in Computer Science","scopus_import":1},{"day":"10","title":"ZIFL1.1 transporter modulates polar auxin transport by stabilizing membrane abundance of multiple PINs in Arabidopsis root tip","volume":8,"article_number":"e25688","status":"public","project":[{"call_identifier":"FP7","grant_number":"282300","name":"Polarity and subcellular dynamics in plants","_id":"25716A02-B435-11E9-9278-68D0E5697425"}],"oa_version":"Submitted Version","date_created":"2018-12-11T11:57:43Z","_id":"2448","type":"journal_article","issue":"10","article_processing_charge":"No","publication":"Plant Signaling & Behavior","author":[{"full_name":"Remy, Estelle","last_name":"Remy","first_name":"Estelle"},{"full_name":"Baster, Pawel","last_name":"Baster","id":"3028BD74-F248-11E8-B48F-1D18A9856A87","first_name":"Pawel"},{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","first_name":"Jirí","last_name":"Friml","orcid":"0000-0002-8302-7596","full_name":"Friml, Jirí"},{"full_name":"Duque, Paula","last_name":"Duque","first_name":"Paula"}],"department":[{"_id":"JiFr"}],"month":"07","date_published":"2013-07-10T00:00:00Z","article_type":"original","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","publisher":"Taylor & Francis","publist_id":"4455","date_updated":"2025-05-07T11:12:32Z","main_file_link":[{"url":"http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091088/","open_access":"1"}],"scopus_import":"1","year":"2013","language":[{"iso":"eng"}],"pmid":1,"intvolume":"         8","doi":"10.4161/psb.25688","citation":{"apa":"Remy, E., Baster, P., Friml, J., &#38; Duque, P. (2013). ZIFL1.1 transporter modulates polar auxin transport by stabilizing membrane abundance of multiple PINs in Arabidopsis root tip. <i>Plant Signaling &#38; Behavior</i>. Taylor &#38; Francis. <a href=\"https://doi.org/10.4161/psb.25688\">https://doi.org/10.4161/psb.25688</a>","short":"E. Remy, P. Baster, J. Friml, P. Duque, Plant Signaling &#38; Behavior 8 (2013).","chicago":"Remy, Estelle, Pawel Baster, Jiří Friml, and Paula Duque. “ZIFL1.1 Transporter Modulates Polar Auxin Transport by Stabilizing Membrane Abundance of Multiple PINs in Arabidopsis Root Tip.” <i>Plant Signaling &#38; Behavior</i>. Taylor &#38; Francis, 2013. <a href=\"https://doi.org/10.4161/psb.25688\">https://doi.org/10.4161/psb.25688</a>.","ista":"Remy E, Baster P, Friml J, Duque P. 2013. ZIFL1.1 transporter modulates polar auxin transport by stabilizing membrane abundance of multiple PINs in Arabidopsis root tip. Plant Signaling &#38; Behavior. 8(10), e25688.","ieee":"E. Remy, P. Baster, J. Friml, and P. Duque, “ZIFL1.1 transporter modulates polar auxin transport by stabilizing membrane abundance of multiple PINs in Arabidopsis root tip,” <i>Plant Signaling &#38; Behavior</i>, vol. 8, no. 10. Taylor &#38; Francis, 2013.","mla":"Remy, Estelle, et al. “ZIFL1.1 Transporter Modulates Polar Auxin Transport by Stabilizing Membrane Abundance of Multiple PINs in Arabidopsis Root Tip.” <i>Plant Signaling &#38; Behavior</i>, vol. 8, no. 10, e25688, Taylor &#38; Francis, 2013, doi:<a href=\"https://doi.org/10.4161/psb.25688\">10.4161/psb.25688</a>.","ama":"Remy E, Baster P, Friml J, Duque P. ZIFL1.1 transporter modulates polar auxin transport by stabilizing membrane abundance of multiple PINs in Arabidopsis root tip. <i>Plant Signaling &#38; Behavior</i>. 2013;8(10). doi:<a href=\"https://doi.org/10.4161/psb.25688\">10.4161/psb.25688</a>"},"quality_controlled":"1","ec_funded":1,"oa":1,"abstract":[{"text":"Cell-to-cell directional flow of the phytohormone auxin is primarily established by polar localization of the PIN auxin transporters, a process tightly regulated at multiple levels by auxin itself. We recently reported that, in the context of strong auxin flows, activity of the vacuolar ZIFL1.1 transporter is required for fine-tuning of polar auxin transport rates in the Arabidopsis root. In particular, ZIFL1.1 function protects plasma-membrane stability of the PIN2 carrier in epidermal root tip cells under conditions normally triggering PIN2 degradation. Here, we show that ZIFL1.1 activity at the root tip also promotes PIN1 plasma-membrane abundance in central cylinder cells, thus supporting the notion that ZIFL1.1 acts as a general positive modulator of polar auxin transport in roots.","lang":"eng"}],"external_id":{"pmid":["23857365"]}},{"citation":{"apa":"Nodzyński, T., Feraru, M., Hirsch, S., De Rycke, R., Nicuales, C., Van Leene, J., … Friml, J. (2013). Retromer subunits VPS35A and VPS29 mediate prevacuolar compartment (PVC) function in Arabidopsis. <i>Molecular Plant</i>. Cell Press. <a href=\"https://doi.org/10.1093/mp/sst044\">https://doi.org/10.1093/mp/sst044</a>","short":"T. Nodzyński, M. Feraru, S. Hirsch, R. De Rycke, C. Nicuales, J. Van Leene, G. De Jaeger, S. Vanneste, J. Friml, Molecular Plant 6 (2013) 1849–1862.","chicago":"Nodzyński, Tomasz, Murguel Feraru, Sibylle Hirsch, Riet De Rycke, Claudiu Nicuales, Jelle Van Leene, Geert De Jaeger, Steffen Vanneste, and Jiří Friml. “Retromer Subunits VPS35A and VPS29 Mediate Prevacuolar Compartment (PVC) Function in Arabidopsis.” <i>Molecular Plant</i>. Cell Press, 2013. <a href=\"https://doi.org/10.1093/mp/sst044\">https://doi.org/10.1093/mp/sst044</a>.","ista":"Nodzyński T, Feraru M, Hirsch S, De Rycke R, Nicuales C, Van Leene J, De Jaeger G, Vanneste S, Friml J. 2013. Retromer subunits VPS35A and VPS29 mediate prevacuolar compartment (PVC) function in Arabidopsis. Molecular Plant. 6(6), 1849–1862.","ieee":"T. Nodzyński <i>et al.</i>, “Retromer subunits VPS35A and VPS29 mediate prevacuolar compartment (PVC) function in Arabidopsis,” <i>Molecular Plant</i>, vol. 6, no. 6. Cell Press, pp. 1849–1862, 2013.","mla":"Nodzyński, Tomasz, et al. “Retromer Subunits VPS35A and VPS29 Mediate Prevacuolar Compartment (PVC) Function in Arabidopsis.” <i>Molecular Plant</i>, vol. 6, no. 6, Cell Press, 2013, pp. 1849–62, doi:<a href=\"https://doi.org/10.1093/mp/sst044\">10.1093/mp/sst044</a>.","ama":"Nodzyński T, Feraru M, Hirsch S, et al. Retromer subunits VPS35A and VPS29 mediate prevacuolar compartment (PVC) function in Arabidopsis. <i>Molecular Plant</i>. 2013;6(6):1849-1862. doi:<a href=\"https://doi.org/10.1093/mp/sst044\">10.1093/mp/sst044</a>"},"doi":"10.1093/mp/sst044","oa_version":"None","quality_controlled":"1","date_created":"2018-12-11T11:57:44Z","_id":"2449","type":"journal_article","issue":"6","publication":"Molecular Plant","author":[{"first_name":"Tomasz","last_name":"Nodzyński","full_name":"Nodzyński, Tomasz"},{"first_name":"Murguel","last_name":"Feraru","full_name":"Feraru, Murguel"},{"full_name":"Hirsch, Sibylle","first_name":"Sibylle","last_name":"Hirsch"},{"full_name":"De Rycke, Riet","last_name":"De Rycke","first_name":"Riet"},{"full_name":"Nicuales, Claudiu","first_name":"Claudiu","last_name":"Nicuales"},{"full_name":"Van Leene, Jelle","first_name":"Jelle","last_name":"Van Leene"},{"first_name":"Geert","last_name":"De Jaeger","full_name":"De Jaeger, Geert"},{"full_name":"Vanneste, Steffen","last_name":"Vanneste","first_name":"Steffen"},{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","first_name":"Jirí","last_name":"Friml","full_name":"Friml, Jirí","orcid":"0000-0002-8302-7596"}],"department":[{"_id":"JiFr"}],"year":"2013","day":"01","language":[{"iso":"eng"}],"volume":6,"title":"Retromer subunits VPS35A and VPS29 mediate prevacuolar compartment (PVC) function in Arabidopsis","intvolume":"         6","status":"public","page":"1849 - 1862","scopus_import":1,"abstract":[{"text":"Intracellular protein routing is mediated by vesicular transport which is tightly regulated in eukaryotes. The protein and lipid homeostasis depends on coordinated delivery of de novo synthesized or recycled cargoes to the plasma membrane by exocytosis and their subsequent removal by rerouting them for recycling or degradation. Here, we report the characterization of protein affected trafficking 3 (pat3) mutant that we identified by an epifluorescence-based forward genetic screen for mutants defective in subcellular distribution of Arabidopsis auxin transporter PIN1–GFP. While pat3 displays largely normal plant morphology and development in nutrient-rich conditions, it shows strong ectopic intracellular accumulations of different plasma membrane cargoes in structures that resemble prevacuolar compartments (PVC) with an aberrant morphology. Genetic mapping revealed that pat3 is defective in vacuolar protein sorting 35A (VPS35A), a putative subunit of the retromer complex that mediates retrograde trafficking between the PVC and trans-Golgi network. Similarly, a mutant defective in another retromer subunit, vps29, shows comparable subcellular defects in PVC morphology and protein accumulation. Thus, our data provide evidence that the retromer components VPS35A and VPS29 are essential for normal PVC morphology and normal trafficking of plasma membrane proteins in plants. In addition, we show that, out of the three VPS35 retromer subunits present in Arabidopsis thaliana genome, the VPS35 homolog A plays a prevailing role in trafficking to the lytic vacuole, presenting another level of complexity in the retromer-dependent vacuolar sorting. ","lang":"eng"}],"month":"11","date_published":"2013-11-01T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","publisher":"Cell Press","publist_id":"4454","date_updated":"2021-01-12T06:57:33Z"},{"title":"Inhomogeneous cubic congruences and rational points on del Pezzo surfaces","status":"public","year":"2013","day":"01","author":[{"full_name":"Baier, Stephan","first_name":"Stephan","last_name":"Baier"},{"id":"35827D50-F248-11E8-B48F-1D18A9856A87","first_name":"Timothy D","last_name":"Browning","orcid":"0000-0002-8314-0177","full_name":"Timothy Browning"}],"citation":{"ama":"Baier S, Browning TD. Inhomogeneous cubic congruences and rational points on del Pezzo surfaces. <i>Journal fur die Reine und Angewandte Mathematik</i>. 2013;(680):69-151. doi:<a href=\"https://doi.org/10.1515/crelle.2012.039\">10.1515/crelle.2012.039</a>","ieee":"S. Baier and T. D. Browning, “Inhomogeneous cubic congruences and rational points on del Pezzo surfaces,” <i>Journal fur die Reine und Angewandte Mathematik</i>, no. 680. Walter de Gruyter, pp. 69–151, 2013.","ista":"Baier S, Browning TD. 2013. Inhomogeneous cubic congruences and rational points on del Pezzo surfaces. Journal fur die Reine und Angewandte Mathematik. (680), 69–151.","mla":"Baier, Stephan, and Timothy D. Browning. “Inhomogeneous Cubic Congruences and Rational Points on Del Pezzo Surfaces.” <i>Journal Fur Die Reine Und Angewandte Mathematik</i>, no. 680, Walter de Gruyter, 2013, pp. 69–151, doi:<a href=\"https://doi.org/10.1515/crelle.2012.039\">10.1515/crelle.2012.039</a>.","apa":"Baier, S., &#38; Browning, T. D. (2013). Inhomogeneous cubic congruences and rational points on del Pezzo surfaces. <i>Journal Fur Die Reine Und Angewandte Mathematik</i>. Walter de Gruyter. <a href=\"https://doi.org/10.1515/crelle.2012.039\">https://doi.org/10.1515/crelle.2012.039</a>","short":"S. Baier, T.D. Browning, Journal Fur Die Reine Und Angewandte Mathematik (2013) 69–151.","chicago":"Baier, Stephan, and Timothy D Browning. “Inhomogeneous Cubic Congruences and Rational Points on Del Pezzo Surfaces.” <i>Journal Fur Die Reine Und Angewandte Mathematik</i>. Walter de Gruyter, 2013. <a href=\"https://doi.org/10.1515/crelle.2012.039\">https://doi.org/10.1515/crelle.2012.039</a>."},"doi":"10.1515/crelle.2012.039","quality_controlled":0,"date_created":"2018-12-11T11:45:24Z","issue":"680","_id":"245","type":"journal_article","publication":"Journal fur die Reine und Angewandte Mathematik","extern":1,"publication_status":"published","publisher":"Walter de Gruyter","publist_id":"7659","date_updated":"2021-01-12T06:57:33Z","oa":1,"abstract":[{"text":"For given non-zero integers a, b, q we investigate the density of solutions (x; y) ∈ ℤ2 to the binary cubic congruence ax2 + by3 ≡ 0 mod q, and use it to establish the Manin conjecture for a singular del Pezzo surface of degree 2 defined over ℚ.","lang":"eng"}],"month":"07","date_published":"2013-07-01T00:00:00Z","page":"69 - 151","main_file_link":[{"url":"https://arxiv.org/abs/1011.3434","open_access":"1"}]},{"title":"Interaction of PLS and PIN and hormonal crosstalk in Arabidopsis root development","volume":4,"status":"public","intvolume":"         4","year":"2013","day":"01","author":[{"full_name":"Liu, Junli","last_name":"Liu","first_name":"Junli"},{"last_name":"Menhi","first_name":"Saher","full_name":"Menhi, Saher"},{"first_name":"Jennifer","last_name":"Topping","full_name":"Topping, Jennifer"},{"first_name":"Jirí","id":"4159519E-F248-11E8-B48F-1D18A9856A87","last_name":"Friml","orcid":"0000-0002-8302-7596","full_name":"Jirí Friml"},{"first_name":"Keith","last_name":"Lindsey","full_name":"Lindsey, Keith"}],"date_created":"2018-12-11T11:57:44Z","quality_controlled":0,"doi":"10.3389/fpls.2013.00075","citation":{"ieee":"J. Liu, S. Menhi, J. Topping, J. Friml, and K. Lindsey, “Interaction of PLS and PIN and hormonal crosstalk in Arabidopsis root development,” <i>Frontiers in Plant Science</i>, vol. 4, no. 75. Frontiers Research Foundation, 2013.","ista":"Liu J, Menhi S, Topping J, Friml J, Lindsey K. 2013. Interaction of PLS and PIN and hormonal crosstalk in Arabidopsis root development. Frontiers in Plant Science. 4(75).","mla":"Liu, Junli, et al. “Interaction of PLS and PIN and Hormonal Crosstalk in Arabidopsis Root Development.” <i>Frontiers in Plant Science</i>, vol. 4, no. 75, Frontiers Research Foundation, 2013, doi:<a href=\"https://doi.org/10.3389/fpls.2013.00075\">10.3389/fpls.2013.00075</a>.","apa":"Liu, J., Menhi, S., Topping, J., Friml, J., &#38; Lindsey, K. (2013). Interaction of PLS and PIN and hormonal crosstalk in Arabidopsis root development. <i>Frontiers in Plant Science</i>. Frontiers Research Foundation. <a href=\"https://doi.org/10.3389/fpls.2013.00075\">https://doi.org/10.3389/fpls.2013.00075</a>","chicago":"Liu, Junli, Saher Menhi, Jennifer Topping, Jiří Friml, and Keith Lindsey. “Interaction of PLS and PIN and Hormonal Crosstalk in Arabidopsis Root Development.” <i>Frontiers in Plant Science</i>. Frontiers Research Foundation, 2013. <a href=\"https://doi.org/10.3389/fpls.2013.00075\">https://doi.org/10.3389/fpls.2013.00075</a>.","short":"J. Liu, S. Menhi, J. Topping, J. Friml, K. Lindsey, Frontiers in Plant Science 4 (2013).","ama":"Liu J, Menhi S, Topping J, Friml J, Lindsey K. Interaction of PLS and PIN and hormonal crosstalk in Arabidopsis root development. <i>Frontiers in Plant Science</i>. 2013;4(75). doi:<a href=\"https://doi.org/10.3389/fpls.2013.00075\">10.3389/fpls.2013.00075</a>"},"publication":"Frontiers in Plant Science","extern":1,"_id":"2450","type":"journal_article","issue":"75","publication_status":"published","publist_id":"4453","date_updated":"2021-01-12T06:57:34Z","publisher":"Frontiers Research Foundation","abstract":[{"lang":"eng","text":"Understanding how hormones and genes interact to coordinate plant growth is a major challenge in developmental biology. The activities of auxin, ethylene, and cytokinin depend on cellular context and exhibit either synergistic or antagonistic interactions. Here we use experimentation and network construction to elucidate the role of the interaction of the POLARIS peptide (PLS) and the auxin efflux carrier PIN proteins in the crosstalk of three hormones (auxin, ethylene, and cytokinin) in Arabidopsis root development. In ethylene hypersignaling mutants such as polaris (pls), we show experimentally that expression of both PIN1 and PIN2 significantly increases. This relationship is analyzed in the context of the crosstalk between auxin, ethylene, and cytokinin: in pls, endogenous auxin, ethylene and cytokinin concentration decreases, approximately remains unchanged and increases, respectively. Experimental data are integrated into a hormonal crosstalk network through combination with information in literature. Network construction reveals that the regulation of both PIN1 and PIN2 is predominantly via ethylene signaling. In addition, it is deduced that the relationship between cytokinin and PIN1 and PIN2 levels implies a regulatory role of cytokinin in addition to its regulation to auxin, ethylene, and PLS levels. We discuss how the network of hormones and genes coordinates plant growth by simultaneously regulating the activities of auxin, ethylene, and cytokinin signaling pathways.hormonal crosstalk, root development, auxin flux, PIN proteins, PLS protein, signaling network"}],"month":"04","date_published":"2013-04-01T00:00:00Z"},{"abstract":[{"text":"Background: Abundance and distribution of the plant hormone auxin play important roles in plant development. Besides other metabolic processes, various auxin carriers control the cellular level of active auxin and, hence, are major regulators of cellular auxin homeostasis. Despite the developmental importance of auxin transporters, a simple medium-to-high throughput approach to assess carrier activities is still missing. Here we show that carrier driven depletion of cellular auxin correlates with reduced nuclear auxin signaling in tobacco Bright Yellow-2 (BY-2) cell cultures.Results: We developed an easy to use transient single-cell-based system to detect carrier activity. We use the relative changes in signaling output of the auxin responsive promoter element DR5 to indirectly visualize auxin carrier activity. The feasibility of the transient approach was demonstrated by pharmacological and genetic interference with auxin signaling and transport. As a proof of concept, we provide visual evidence that the prominent auxin transport proteins PIN-FORMED (PIN)2 and PIN5 regulate cellular auxin homeostasis at the plasma membrane and endoplasmic reticulum (ER), respectively. Our data suggest that PIN2 and PIN5 have different sensitivities to the auxin transport inhibitor 1-naphthylphthalamic acid (NPA). Also the putative PIN-LIKES (PILS) auxin carrier activity at the ER is insensitive to NPA in our system, indicating that NPA blocks intercellular, but not intracellular auxin transport.Conclusions: This single-cell-based system is a useful tool by which the activity of putative auxin carriers, such as PINs, PILS and WALLS ARE THIN1 (WAT1), can be indirectly visualized in a medium-to-high throughput manner. Moreover, our single cell system might be useful to investigate also other hormonal signaling pathways, such as cytokinin.","lang":"eng"}],"date_published":"2013-02-01T00:00:00Z","month":"02","publication_status":"published","date_updated":"2021-01-12T06:57:34Z","publist_id":"4451","publisher":"BioMed Central","day":"01","year":"2013","title":"Single-cell-based system to monitor carrier driven cellular auxin homeostasis","volume":13,"intvolume":"        13","status":"public","date_created":"2018-12-11T11:57:45Z","quality_controlled":0,"doi":"10.1186/1471-2229-13-20","citation":{"ama":"Barbez E, Laňková M, Pařezová M, et al. Single-cell-based system to monitor carrier driven cellular auxin homeostasis. <i>BMC Plant Biology</i>. 2013;13(1). doi:<a href=\"https://doi.org/10.1186/1471-2229-13-20\">10.1186/1471-2229-13-20</a>","chicago":"Barbez, Elke, Martina Laňková, Markéta Pařezová, Alexis Maizel, Eva Zažímalová, Jan Petrášek, Jiří Friml, and Jürgen Kleine Vehn. “Single-Cell-Based System to Monitor Carrier Driven Cellular Auxin Homeostasis.” <i>BMC Plant Biology</i>. BioMed Central, 2013. <a href=\"https://doi.org/10.1186/1471-2229-13-20\">https://doi.org/10.1186/1471-2229-13-20</a>.","short":"E. Barbez, M. Laňková, M. Pařezová, A. Maizel, E. Zažímalová, J. Petrášek, J. Friml, J. Kleine Vehn, BMC Plant Biology 13 (2013).","apa":"Barbez, E., Laňková, M., Pařezová, M., Maizel, A., Zažímalová, E., Petrášek, J., … Kleine Vehn, J. (2013). Single-cell-based system to monitor carrier driven cellular auxin homeostasis. <i>BMC Plant Biology</i>. BioMed Central. <a href=\"https://doi.org/10.1186/1471-2229-13-20\">https://doi.org/10.1186/1471-2229-13-20</a>","mla":"Barbez, Elke, et al. “Single-Cell-Based System to Monitor Carrier Driven Cellular Auxin Homeostasis.” <i>BMC Plant Biology</i>, vol. 13, no. 1, BioMed Central, 2013, doi:<a href=\"https://doi.org/10.1186/1471-2229-13-20\">10.1186/1471-2229-13-20</a>.","ieee":"E. Barbez <i>et al.</i>, “Single-cell-based system to monitor carrier driven cellular auxin homeostasis,” <i>BMC Plant Biology</i>, vol. 13, no. 1. BioMed Central, 2013.","ista":"Barbez E, Laňková M, Pařezová M, Maizel A, Zažímalová E, Petrášek J, Friml J, Kleine Vehn J. 2013. Single-cell-based system to monitor carrier driven cellular auxin homeostasis. BMC Plant Biology. 13(1)."},"extern":1,"publication":"BMC Plant Biology","issue":"1","_id":"2452","type":"journal_article","author":[{"first_name":"Elke","last_name":"Barbez","full_name":"Barbez, Elke"},{"full_name":"Laňková, Martina","first_name":"Martina","last_name":"Laňková"},{"full_name":"Pařezová, Markéta","last_name":"Pařezová","first_name":"Markéta"},{"first_name":"Alexis","last_name":"Maizel","full_name":"Maizel, Alexis"},{"full_name":"Zažímalová, Eva","last_name":"Zažímalová","first_name":"Eva"},{"last_name":"Petrášek","first_name":"Jan","full_name":"Petrášek, Jan"},{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","first_name":"Jirí","last_name":"Friml","orcid":"0000-0002-8302-7596","full_name":"Jirí Friml"},{"last_name":"Kleine Vehn","first_name":"Jürgen","full_name":"Kleine-Vehn, Jürgen"}]},{"page":"5 - 10","month":"01","date_published":"2013-01-01T00:00:00Z","publisher":"Cell Press","date_updated":"2021-01-12T06:57:36Z","publist_id":"4446","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","publication_status":"published","_id":"2457","issue":"1","type":"journal_article","publication":"Trends in Plant Science","extern":"1","doi":"10.1016/j.tplants.2012.08.009","citation":{"ama":"Viaene T, Delwiche C, Rensing S, Friml J. Origin and evolution of PIN auxin transporters in the green lineage. <i>Trends in Plant Science</i>. 2013;18(1):5-10. doi:<a href=\"https://doi.org/10.1016/j.tplants.2012.08.009\">10.1016/j.tplants.2012.08.009</a>","apa":"Viaene, T., Delwiche, C., Rensing, S., &#38; Friml, J. (2013). Origin and evolution of PIN auxin transporters in the green lineage. <i>Trends in Plant Science</i>. Cell Press. <a href=\"https://doi.org/10.1016/j.tplants.2012.08.009\">https://doi.org/10.1016/j.tplants.2012.08.009</a>","chicago":"Viaene, Tom, Charles Delwiche, Stefan Rensing, and Jiří Friml. “Origin and Evolution of PIN Auxin Transporters in the Green Lineage.” <i>Trends in Plant Science</i>. Cell Press, 2013. <a href=\"https://doi.org/10.1016/j.tplants.2012.08.009\">https://doi.org/10.1016/j.tplants.2012.08.009</a>.","short":"T. Viaene, C. Delwiche, S. Rensing, J. Friml, Trends in Plant Science 18 (2013) 5–10.","ista":"Viaene T, Delwiche C, Rensing S, Friml J. 2013. Origin and evolution of PIN auxin transporters in the green lineage. Trends in Plant Science. 18(1), 5–10.","ieee":"T. Viaene, C. Delwiche, S. Rensing, and J. Friml, “Origin and evolution of PIN auxin transporters in the green lineage,” <i>Trends in Plant Science</i>, vol. 18, no. 1. Cell Press, pp. 5–10, 2013.","mla":"Viaene, Tom, et al. “Origin and Evolution of PIN Auxin Transporters in the Green Lineage.” <i>Trends in Plant Science</i>, vol. 18, no. 1, Cell Press, 2013, pp. 5–10, doi:<a href=\"https://doi.org/10.1016/j.tplants.2012.08.009\">10.1016/j.tplants.2012.08.009</a>."},"date_created":"2018-12-11T11:57:46Z","oa_version":"None","quality_controlled":"1","author":[{"first_name":"Tom","last_name":"Viaene","full_name":"Viaene, Tom"},{"full_name":"Delwiche, Charles","first_name":"Charles","last_name":"Delwiche"},{"last_name":"Rensing","first_name":"Stefan","full_name":"Rensing, Stefan"},{"full_name":"Friml, Jirí","orcid":"0000-0002-8302-7596","last_name":"Friml","first_name":"Jirí","id":"4159519E-F248-11E8-B48F-1D18A9856A87"}],"language":[{"iso":"eng"}],"year":"2013","day":"01","status":"public","intvolume":"        18","title":"Origin and evolution of PIN auxin transporters in the green lineage","volume":18},{"publication_status":"published","publisher":"Cambridge University Press","publist_id":"7658","date_updated":"2021-01-12T06:57:37Z","abstract":[{"text":"Given an intersection of two quadrics X Pm1, with m &gt; 9, the quantitative arithmetic of the set X(Q) is investigated under the assumption that the singular locus of X consists of a pair of conjugate singular points defined over Q(i).","lang":"eng"}],"date_published":"2013-09-01T00:00:00Z","month":"09","page":"1457 - 1494","volume":149,"title":"Rational points on singular intersections of quadrics","status":"public","intvolume":"       149","day":"01","year":"2013","author":[{"id":"35827D50-F248-11E8-B48F-1D18A9856A87","first_name":"Timothy D","last_name":"Browning","full_name":"Timothy Browning","orcid":"0000-0002-8314-0177"},{"first_name":"Ritabrata","last_name":"Munshi","full_name":"Munshi, Ritabrata"}],"acknowledgement":"EP/E053262/1\tEngineering and Physical Sciences Research Council","citation":{"chicago":"Browning, Timothy D, and Ritabrata Munshi. “Rational Points on Singular Intersections of Quadrics.” <i>Compositio Mathematica</i>. Cambridge University Press, 2013. <a href=\"https://doi.org/10.1112/S0010437X13007185\">https://doi.org/10.1112/S0010437X13007185</a>.","short":"T.D. Browning, R. Munshi, Compositio Mathematica 149 (2013) 1457–1494.","apa":"Browning, T. D., &#38; Munshi, R. (2013). Rational points on singular intersections of quadrics. <i>Compositio Mathematica</i>. Cambridge University Press. <a href=\"https://doi.org/10.1112/S0010437X13007185\">https://doi.org/10.1112/S0010437X13007185</a>","mla":"Browning, Timothy D., and Ritabrata Munshi. “Rational Points on Singular Intersections of Quadrics.” <i>Compositio Mathematica</i>, vol. 149, no. 9, Cambridge University Press, 2013, pp. 1457–94, doi:<a href=\"https://doi.org/10.1112/S0010437X13007185\">10.1112/S0010437X13007185</a>.","ista":"Browning TD, Munshi R. 2013. Rational points on singular intersections of quadrics. Compositio Mathematica. 149(9), 1457–1494.","ieee":"T. D. Browning and R. Munshi, “Rational points on singular intersections of quadrics,” <i>Compositio Mathematica</i>, vol. 149, no. 9. Cambridge University Press, pp. 1457–1494, 2013.","ama":"Browning TD, Munshi R. Rational points on singular intersections of quadrics. <i>Compositio Mathematica</i>. 2013;149(9):1457-1494. doi:<a href=\"https://doi.org/10.1112/S0010437X13007185\">10.1112/S0010437X13007185</a>"},"doi":"10.1112/S0010437X13007185","date_created":"2018-12-11T11:45:25Z","quality_controlled":0,"type":"journal_article","_id":"246","issue":"9","publication":"Compositio Mathematica","extern":1},{"doi":"10.1145/2461912.2461982","quality_controlled":"1","year":"2013","language":[{"iso":"eng"}],"has_accepted_license":"1","intvolume":"        32","oa":1,"ddc":["000"],"abstract":[{"text":"We introduce a new method for efficiently simulating liquid with extreme amounts of spatial adaptivity. Our method combines several key components to drastically speed up the simulation of large-scale fluid phenomena: We leverage an alternative Eulerian tetrahedral mesh discretization to significantly reduce the complexity of the pressure solve while increasing the robustness with respect to element quality and removing the possibility of locking. Next, we enable subtle free-surface phenomena by deriving novel second-order boundary conditions consistent with our discretization. We couple this discretization with a spatially adaptive Fluid-Implicit Particle (FLIP) method, enabling efficient, robust, minimally-dissipative simulations that can undergo sharp changes in spatial resolution while minimizing artifacts. Along the way, we provide a new method for generating a smooth and detailed surface from a set of particles with variable sizes. Finally, we explore several new sizing functions for determining spatially adaptive simulation resolutions, and we show how to couple them to our simulator. We combine each of these elements to produce a simulation algorithm that is capable of creating animations at high maximum resolutions while avoiding common pitfalls like inaccurate boundary conditions and inefficient computation.","lang":"eng"}],"file":[{"date_updated":"2020-07-14T12:45:41Z","checksum":"aeea6b0ff2b27c695aeb8408c7d2fc50","file_size":8601561,"creator":"system","content_type":"application/pdf","relation":"main_file","file_name":"IST-2016-605-v1+1_tetflip_fixed.pdf","file_id":"5279","access_level":"open_access","date_created":"2018-12-12T10:17:25Z"}],"pubrep_id":"605","date_created":"2018-12-11T11:57:50Z","oa_version":"Submitted Version","type":"journal_article","_id":"2466","issue":"4","article_processing_charge":"No","file_date_updated":"2020-07-14T12:45:41Z","publication":"ACM Transactions on Graphics","author":[{"full_name":"Ando, Ryoichi","last_name":"Ando","first_name":"Ryoichi"},{"first_name":"Nils","last_name":"Thuerey","full_name":"Thuerey, Nils"},{"last_name":"Wojtan","id":"3C61F1D2-F248-11E8-B48F-1D18A9856A87","first_name":"Christopher J","orcid":"0000-0001-6646-5546","full_name":"Wojtan, Christopher J"}],"department":[{"_id":"ChWo"}],"day":"01","title":"Highly adaptive liquid simulations on tetrahedral meshes","volume":32,"article_number":"103","status":"public","scopus_import":"1","date_published":"2013-07-01T00:00:00Z","month":"07","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","publisher":"ACM","publist_id":"4436","date_updated":"2024-11-19T11:56:45Z"},{"scopus_import":1,"month":"07","date_published":"2013-07-01T00:00:00Z","publisher":"ACM","date_updated":"2023-02-23T10:44:16Z","publist_id":"4435","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","type":"journal_article","_id":"2467","issue":"4","file_date_updated":"2020-07-14T12:45:41Z","publication":"ACM Transactions on Graphics","oa_version":"Submitted Version","date_created":"2018-12-11T11:57:50Z","pubrep_id":"604","department":[{"_id":"ChWo"}],"author":[{"full_name":"Bernstein, Gilbert","last_name":"Bernstein","first_name":"Gilbert"},{"id":"3C61F1D2-F248-11E8-B48F-1D18A9856A87","first_name":"Christopher J","last_name":"Wojtan","orcid":"0000-0001-6646-5546","full_name":"Wojtan, Christopher J"}],"day":"01","article_number":"34","status":"public","volume":32,"title":"Putting holes in holey geometry: Topology change for arbitrary surfaces","file":[{"relation":"main_file","file_name":"IST-2016-604-v1+1_toptop2013.pdf","content_type":"application/pdf","date_created":"2018-12-12T10:09:43Z","access_level":"open_access","file_id":"4768","date_updated":"2020-07-14T12:45:41Z","creator":"system","checksum":"9c8425d62246996ca632c5a01870515b","file_size":3514674}],"oa":1,"ddc":["000"],"abstract":[{"lang":"eng","text":"This paper presents a method for computing topology changes for triangle meshes in an interactive geometric modeling environment. Most triangle meshes in practice do not exhibit desirable geometric properties, so we develop a solution that is independent of standard assumptions and robust to geometric errors. Specifically, we provide the first method for topology change applicable to arbitrary non-solid, non-manifold, non-closed, self-intersecting surfaces. We prove that this new method for topology change produces the expected conventional results when applied to solid (closed, manifold, non-self-intersecting) surfaces---that is, we prove a backwards-compatibility property relative to prior work. Beyond solid surfaces, we present empirical evidence that our method remains tolerant to a variety of surface aberrations through the incorporation of a novel error correction scheme. Finally, we demonstrate how topology change applied to non-solid objects enables wholly new and useful behaviors."}],"doi":"10.1145/2461912.2462027","citation":{"short":"G. Bernstein, C. Wojtan, ACM Transactions on Graphics 32 (2013).","chicago":"Bernstein, Gilbert, and Chris Wojtan. “Putting Holes in Holey Geometry: Topology Change for Arbitrary Surfaces.” <i>ACM Transactions on Graphics</i>. ACM, 2013. <a href=\"https://doi.org/10.1145/2461912.2462027\">https://doi.org/10.1145/2461912.2462027</a>.","apa":"Bernstein, G., &#38; Wojtan, C. (2013). Putting holes in holey geometry: Topology change for arbitrary surfaces. <i>ACM Transactions on Graphics</i>. ACM. <a href=\"https://doi.org/10.1145/2461912.2462027\">https://doi.org/10.1145/2461912.2462027</a>","mla":"Bernstein, Gilbert, and Chris Wojtan. “Putting Holes in Holey Geometry: Topology Change for Arbitrary Surfaces.” <i>ACM Transactions on Graphics</i>, vol. 32, no. 4, 34, ACM, 2013, doi:<a href=\"https://doi.org/10.1145/2461912.2462027\">10.1145/2461912.2462027</a>.","ieee":"G. Bernstein and C. Wojtan, “Putting holes in holey geometry: Topology change for arbitrary surfaces,” <i>ACM Transactions on Graphics</i>, vol. 32, no. 4. ACM, 2013.","ista":"Bernstein G, Wojtan C. 2013. Putting holes in holey geometry: Topology change for arbitrary surfaces. ACM Transactions on Graphics. 32(4), 34.","ama":"Bernstein G, Wojtan C. Putting holes in holey geometry: Topology change for arbitrary surfaces. <i>ACM Transactions on Graphics</i>. 2013;32(4). doi:<a href=\"https://doi.org/10.1145/2461912.2462027\">10.1145/2461912.2462027</a>"},"quality_controlled":"1","language":[{"iso":"eng"}],"year":"2013","intvolume":"        32","has_accepted_license":"1"},{"oa":1,"ddc":["000"],"abstract":[{"text":"Our work concerns the combination of an Eulerian liquid simulation with a high-resolution surface tracker (e.g. the level set method or a Lagrangian triangle mesh). The naive application of a high-resolution surface tracker to a low-resolution velocity field can produce many visually disturbing physical and topological artifacts that limit their use in practice. We address these problems by defining an error function which compares the current state of the surface tracker to the set of physically valid surface states. By reducing this error with a gradient descent technique, we introduce a novel physics-based surface fairing method. Similarly, by treating this error function as a potential energy, we derive a new surface correction force that mimics the vortex sheet equations. We demonstrate our results with both level set and mesh-based surface trackers.","lang":"eng"}],"file":[{"content_type":"application/pdf","file_name":"IST-2016-603-v1+1_liquidError_web.pdf","relation":"main_file","file_id":"4761","access_level":"open_access","date_created":"2018-12-12T10:09:37Z","date_updated":"2020-07-14T12:45:41Z","checksum":"53d905e0180e23ef3e813b969ffed4e1","file_size":5813685,"creator":"system"}],"has_accepted_license":"1","intvolume":"        32","year":"2013","language":[{"iso":"eng"}],"citation":{"ama":"Bojsen-Hansen M, Wojtan C. Liquid surface tracking with error compensation. <i>ACM Transactions on Graphics</i>. 2013;32(4). doi:<a href=\"https://doi.org/10.1145/2461912.2461991\">10.1145/2461912.2461991</a>","ieee":"M. Bojsen-Hansen and C. Wojtan, “Liquid surface tracking with error compensation,” <i>ACM Transactions on Graphics</i>, vol. 32, no. 4. ACM, 2013.","ista":"Bojsen-Hansen M, Wojtan C. 2013. Liquid surface tracking with error compensation. ACM Transactions on Graphics. 32(4), 68.","mla":"Bojsen-Hansen, Morten, and Chris Wojtan. “Liquid Surface Tracking with Error Compensation.” <i>ACM Transactions on Graphics</i>, vol. 32, no. 4, 68, ACM, 2013, doi:<a href=\"https://doi.org/10.1145/2461912.2461991\">10.1145/2461912.2461991</a>.","apa":"Bojsen-Hansen, M., &#38; Wojtan, C. (2013). Liquid surface tracking with error compensation. <i>ACM Transactions on Graphics</i>. ACM. <a href=\"https://doi.org/10.1145/2461912.2461991\">https://doi.org/10.1145/2461912.2461991</a>","short":"M. Bojsen-Hansen, C. Wojtan, ACM Transactions on Graphics 32 (2013).","chicago":"Bojsen-Hansen, Morten, and Chris Wojtan. “Liquid Surface Tracking with Error Compensation.” <i>ACM Transactions on Graphics</i>. ACM, 2013. <a href=\"https://doi.org/10.1145/2461912.2461991\">https://doi.org/10.1145/2461912.2461991</a>."},"doi":"10.1145/2461912.2461991","quality_controlled":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","publisher":"ACM","publist_id":"4434","date_updated":"2023-02-23T10:44:18Z","date_published":"2013-07-01T00:00:00Z","month":"07","scopus_import":1,"volume":32,"title":"Liquid surface tracking with error compensation","article_number":"68","status":"public","day":"01","author":[{"last_name":"Bojsen-Hansen","first_name":"Morten","id":"439F0C8C-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-4417-3224","full_name":"Bojsen-Hansen, Morten"},{"full_name":"Wojtan, Christopher J","orcid":"0000-0001-6646-5546","last_name":"Wojtan","first_name":"Christopher J","id":"3C61F1D2-F248-11E8-B48F-1D18A9856A87"}],"department":[{"_id":"ChWo"}],"pubrep_id":"603","oa_version":"Submitted Version","date_created":"2018-12-11T11:57:50Z","_id":"2468","type":"journal_article","issue":"4","file_date_updated":"2020-07-14T12:45:41Z","publication":"ACM Transactions on Graphics"},{"month":"07","date_published":"2013-07-22T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","publisher":"Cell Press","date_updated":"2021-01-12T06:57:40Z","publist_id":"4433","scopus_import":1,"day":"22","volume":23,"tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"title":"Three functions of cadherins in cell adhesion","status":"public","oa_version":"Published Version","date_created":"2018-12-11T11:57:51Z","_id":"2469","issue":"14","type":"journal_article","publication":"Current Biology","file_date_updated":"2020-07-14T12:45:41Z","author":[{"orcid":"0000-0002-3688-1474","full_name":"Maître, Jean-Léon","last_name":"Maître","first_name":"Jean-Léon","id":"48F1E0D8-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Heisenberg","first_name":"Carl-Philipp J","id":"39427864-F248-11E8-B48F-1D18A9856A87","full_name":"Heisenberg, Carl-Philipp J","orcid":"0000-0002-0912-4566"}],"department":[{"_id":"CaHe"}],"ddc":["570"],"oa":1,"abstract":[{"text":"Cadherins are transmembrane proteins that mediate cell–cell adhesion in animals. By regulating contact formation and stability, cadherins play a crucial role in tissue morphogenesis and homeostasis. Here, we review the three major  unctions of cadherins in cell–cell contact formation and stability. Two of those functions lead to a decrease in interfacial ension at the forming cell–cell contact, thereby promoting contact expansion — first, by providing adhesion tension that lowers interfacial tension at the cell–cell contact, and second, by signaling to the actomyosin cytoskeleton in order to reduce cortex tension and thus interfacial tension at the contact. The third function of cadherins in cell–cell contact formation is to stabilize the contact by resisting mechanical forces that pull on the contact.","lang":"eng"}],"file":[{"date_created":"2019-01-24T15:40:22Z","access_level":"open_access","file_id":"5881","relation":"main_file","file_name":"2013_CurrentBiology_Maitre.pdf","content_type":"application/pdf","creator":"dernst","checksum":"6a424b2f007b41d4955a9135793b2162","file_size":247320,"date_updated":"2020-07-14T12:45:41Z"}],"page":"R626 - R633","external_id":{"pmid":["23885883"]},"year":"2013","language":[{"iso":"eng"}],"has_accepted_license":"1","pmid":1,"intvolume":"        23","citation":{"short":"J.-L. Maître, C.-P.J. Heisenberg, Current Biology 23 (2013) R626–R633.","chicago":"Maître, Jean-Léon, and Carl-Philipp J Heisenberg. “Three Functions of Cadherins in Cell Adhesion.” <i>Current Biology</i>. Cell Press, 2013. <a href=\"https://doi.org/10.1016/j.cub.2013.06.019\">https://doi.org/10.1016/j.cub.2013.06.019</a>.","apa":"Maître, J.-L., &#38; Heisenberg, C.-P. J. (2013). Three functions of cadherins in cell adhesion. <i>Current Biology</i>. Cell Press. <a href=\"https://doi.org/10.1016/j.cub.2013.06.019\">https://doi.org/10.1016/j.cub.2013.06.019</a>","mla":"Maître, Jean-Léon, and Carl-Philipp J. Heisenberg. “Three Functions of Cadherins in Cell Adhesion.” <i>Current Biology</i>, vol. 23, no. 14, Cell Press, 2013, pp. R626–33, doi:<a href=\"https://doi.org/10.1016/j.cub.2013.06.019\">10.1016/j.cub.2013.06.019</a>.","ista":"Maître J-L, Heisenberg C-PJ. 2013. Three functions of cadherins in cell adhesion. Current Biology. 23(14), R626–R633.","ieee":"J.-L. Maître and C.-P. J. Heisenberg, “Three functions of cadherins in cell adhesion,” <i>Current Biology</i>, vol. 23, no. 14. Cell Press, pp. R626–R633, 2013.","ama":"Maître J-L, Heisenberg C-PJ. Three functions of cadherins in cell adhesion. <i>Current Biology</i>. 2013;23(14):R626-R633. doi:<a href=\"https://doi.org/10.1016/j.cub.2013.06.019\">10.1016/j.cub.2013.06.019</a>"},"doi":"10.1016/j.cub.2013.06.019","quality_controlled":"1"},{"page":"500 - 502","publication_status":"published","date_updated":"2021-01-12T06:57:40Z","publist_id":"7657","publisher":"Unknown","abstract":[{"text":"An improved estimate is provided for the number of Fq-rational points on a geometrically irreducible, projective, cubic hypersurface that is not equal to a cone.","lang":"eng"}],"month":"08","date_published":"2013-08-31T00:00:00Z","author":[{"id":"35827D50-F248-11E8-B48F-1D18A9856A87","first_name":"Timothy D","last_name":"Browning","full_name":"Timothy Browning","orcid":"0000-0002-8314-0177"}],"acknowledgement":"EP/E053262/1\tEngineering and Physical Sciences Research Council","quality_controlled":0,"date_created":"2018-12-11T11:45:25Z","doi":"10.4153/CMB-2011-177-4","citation":{"ama":"Browning TD. The Lang-Weil estimate for cubic hypersurfaces. <i>Canadian Mathematical Bulletin</i>. 2013;56(3):500-502. doi:<a href=\"https://doi.org/10.4153/CMB-2011-177-4\">10.4153/CMB-2011-177-4</a>","ieee":"T. D. Browning, “The Lang-Weil estimate for cubic hypersurfaces,” <i>Canadian Mathematical Bulletin</i>, vol. 56, no. 3. Unknown, pp. 500–502, 2013.","ista":"Browning TD. 2013. The Lang-Weil estimate for cubic hypersurfaces. Canadian Mathematical Bulletin. 56(3), 500–502.","mla":"Browning, Timothy D. “The Lang-Weil Estimate for Cubic Hypersurfaces.” <i>Canadian Mathematical Bulletin</i>, vol. 56, no. 3, Unknown, 2013, pp. 500–02, doi:<a href=\"https://doi.org/10.4153/CMB-2011-177-4\">10.4153/CMB-2011-177-4</a>.","apa":"Browning, T. D. (2013). The Lang-Weil estimate for cubic hypersurfaces. <i>Canadian Mathematical Bulletin</i>. Unknown. <a href=\"https://doi.org/10.4153/CMB-2011-177-4\">https://doi.org/10.4153/CMB-2011-177-4</a>","chicago":"Browning, Timothy D. “The Lang-Weil Estimate for Cubic Hypersurfaces.” <i>Canadian Mathematical Bulletin</i>. Unknown, 2013. <a href=\"https://doi.org/10.4153/CMB-2011-177-4\">https://doi.org/10.4153/CMB-2011-177-4</a>.","short":"T.D. Browning, Canadian Mathematical Bulletin 56 (2013) 500–502."},"extern":1,"publication":"Canadian Mathematical Bulletin","_id":"247","type":"journal_article","issue":"3","volume":56,"title":"The Lang-Weil estimate for cubic hypersurfaces","intvolume":"        56","status":"public","year":"2013","day":"31"},{"scopus_import":1,"month":"07","date_published":"2013-07-23T00:00:00Z","publisher":"Public Library of Science","date_updated":"2021-01-12T06:57:40Z","publist_id":"4432","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","_id":"2470","type":"journal_article","issue":"7","file_date_updated":"2020-07-14T12:45:41Z","publication":"PLoS One","date_created":"2018-12-11T11:57:51Z","pubrep_id":"413","oa_version":"Published Version","department":[{"_id":"JiFr"}],"author":[{"first_name":"Milada","last_name":"Čovanová","full_name":"Čovanová, Milada"},{"full_name":"Sauer, Michael","last_name":"Sauer","first_name":"Michael"},{"last_name":"Rychtář","first_name":"Jan","full_name":"Rychtář, Jan"},{"full_name":"Friml, Jirí","orcid":"0000-0002-8302-7596","first_name":"Jirí","id":"4159519E-F248-11E8-B48F-1D18A9856A87","last_name":"Friml"},{"full_name":"Petrášek, Jan","first_name":"Jan","last_name":"Petrášek"},{"full_name":"Zažímalová, Eva","first_name":"Eva","last_name":"Zažímalová"}],"day":"23","article_number":"e70050","status":"public","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"volume":8,"title":"Overexpression of the auxin binding PROTEIN1 modulates PIN-dependent auxin transport in tobacco cells","file":[{"file_id":"4681","access_level":"open_access","date_created":"2018-12-12T10:08:21Z","content_type":"application/pdf","file_name":"IST-2016-413-v1+1_journal.pone.0070050.pdf","relation":"main_file","checksum":"2d47ef47616ef4de1d517d146548184e","file_size":2294955,"creator":"system","date_updated":"2020-07-14T12:45:41Z"}],"ddc":["570"],"oa":1,"abstract":[{"text":"Background:Auxin binding protein 1 (ABP1) is a putative auxin receptor and its function is indispensable for plant growth and development. ABP1 has been shown to be involved in auxin-dependent regulation of cell division and expansion, in plasma-membrane-related processes such as changes in transmembrane potential, and in the regulation of clathrin-dependent endocytosis. However, the ABP1-regulated downstream pathway remains elusive.Methodology/Principal Findings:Using auxin transport assays and quantitative analysis of cellular morphology we show that ABP1 regulates auxin efflux from tobacco BY-2 cells. The overexpression of ABP1can counterbalance increased auxin efflux and auxin starvation phenotypes caused by the overexpression of PIN auxin efflux carrier. Relevant mechanism involves the ABP1-controlled vesicle trafficking processes, including positive regulation of endocytosis of PIN auxin efflux carriers, as indicated by fluorescence recovery after photobleaching (FRAP) and pharmacological manipulations.Conclusions/Significance:The findings indicate the involvement of ABP1 in control of rate of auxin transport across plasma membrane emphasizing the role of ABP1 in regulation of PIN activity at the plasma membrane, and highlighting the relevance of ABP1 for the formation of developmentally important, PIN-dependent auxin gradients.","lang":"eng"}],"citation":{"ama":"Čovanová M, Sauer M, Rychtář J, Friml J, Petrášek J, Zažímalová E. Overexpression of the auxin binding PROTEIN1 modulates PIN-dependent auxin transport in tobacco cells. <i>PLoS One</i>. 2013;8(7). doi:<a href=\"https://doi.org/10.1371/journal.pone.0070050\">10.1371/journal.pone.0070050</a>","apa":"Čovanová, M., Sauer, M., Rychtář, J., Friml, J., Petrášek, J., &#38; Zažímalová, E. (2013). Overexpression of the auxin binding PROTEIN1 modulates PIN-dependent auxin transport in tobacco cells. <i>PLoS One</i>. Public Library of Science. <a href=\"https://doi.org/10.1371/journal.pone.0070050\">https://doi.org/10.1371/journal.pone.0070050</a>","chicago":"Čovanová, Milada, Michael Sauer, Jan Rychtář, Jiří Friml, Jan Petrášek, and Eva Zažímalová. “Overexpression of the Auxin Binding PROTEIN1 Modulates PIN-Dependent Auxin Transport in Tobacco Cells.” <i>PLoS One</i>. Public Library of Science, 2013. <a href=\"https://doi.org/10.1371/journal.pone.0070050\">https://doi.org/10.1371/journal.pone.0070050</a>.","short":"M. Čovanová, M. Sauer, J. Rychtář, J. Friml, J. Petrášek, E. Zažímalová, PLoS One 8 (2013).","ieee":"M. Čovanová, M. Sauer, J. Rychtář, J. Friml, J. Petrášek, and E. Zažímalová, “Overexpression of the auxin binding PROTEIN1 modulates PIN-dependent auxin transport in tobacco cells,” <i>PLoS One</i>, vol. 8, no. 7. Public Library of Science, 2013.","ista":"Čovanová M, Sauer M, Rychtář J, Friml J, Petrášek J, Zažímalová E. 2013. Overexpression of the auxin binding PROTEIN1 modulates PIN-dependent auxin transport in tobacco cells. PLoS One. 8(7), e70050.","mla":"Čovanová, Milada, et al. “Overexpression of the Auxin Binding PROTEIN1 Modulates PIN-Dependent Auxin Transport in Tobacco Cells.” <i>PLoS One</i>, vol. 8, no. 7, e70050, Public Library of Science, 2013, doi:<a href=\"https://doi.org/10.1371/journal.pone.0070050\">10.1371/journal.pone.0070050</a>."},"doi":"10.1371/journal.pone.0070050","quality_controlled":"1","language":[{"iso":"eng"}],"year":"2013","intvolume":"         8","has_accepted_license":"1"}]