[{"day":"01","title":"Sublinear-time decremental algorithms for single-source reachability and shortest paths on directed graphs","status":"public","article_number":"674 - 683","date_created":"2022-08-16T09:41:57Z","oa_version":"Preprint","publication":"46th Annual ACM Symposium on Theory of Computing","type":"conference","_id":"11870","article_processing_charge":"No","author":[{"full_name":"Henzinger, Monika H","orcid":"0000-0002-5008-6530","last_name":"Henzinger","id":"540c9bbd-f2de-11ec-812d-d04a5be85630","first_name":"Monika H"},{"full_name":"Krinninger, Sebastian","last_name":"Krinninger","first_name":"Sebastian"},{"first_name":"Danupon","last_name":"Nanongkai","full_name":"Nanongkai, Danupon"}],"month":"05","date_published":"2014-05-01T00:00:00Z","publication_status":"published","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2023-02-17T11:18:52Z","publisher":"Association for Computing Machinery","main_file_link":[{"url":"https://arxiv.org/abs/1504.07959","open_access":"1"}],"scopus_import":"1","year":"2014","publication_identifier":{"isbn":["978-145032710-7"],"issn":["0737-8017"]},"language":[{"iso":"eng"}],"arxiv":1,"quality_controlled":"1","doi":"10.1145/2591796.2591869","citation":{"ama":"Henzinger MH, Krinninger S, Nanongkai D. Sublinear-time decremental algorithms for single-source reachability and shortest paths on directed graphs. In: 46th Annual ACM Symposium on Theory of Computing. Association for Computing Machinery; 2014. doi:10.1145/2591796.2591869","apa":"Henzinger, M. H., Krinninger, S., & Nanongkai, D. (2014). Sublinear-time decremental algorithms for single-source reachability and shortest paths on directed graphs. In 46th Annual ACM Symposium on Theory of Computing. New York, NY, United States: Association for Computing Machinery. https://doi.org/10.1145/2591796.2591869","chicago":"Henzinger, Monika H, Sebastian Krinninger, and Danupon Nanongkai. “Sublinear-Time Decremental Algorithms for Single-Source Reachability and Shortest Paths on Directed Graphs.” In 46th Annual ACM Symposium on Theory of Computing. Association for Computing Machinery, 2014. https://doi.org/10.1145/2591796.2591869.","short":"M.H. Henzinger, S. Krinninger, D. Nanongkai, in:, 46th Annual ACM Symposium on Theory of Computing, Association for Computing Machinery, 2014.","ista":"Henzinger MH, Krinninger S, Nanongkai D. 2014. Sublinear-time decremental algorithms for single-source reachability and shortest paths on directed graphs. 46th Annual ACM Symposium on Theory of Computing. STOC: Symposium on Theory of Computing, 674–683.","ieee":"M. H. Henzinger, S. Krinninger, and D. Nanongkai, “Sublinear-time decremental algorithms for single-source reachability and shortest paths on directed graphs,” in 46th Annual ACM Symposium on Theory of Computing, New York, NY, United States, 2014.","mla":"Henzinger, Monika H., et al. “Sublinear-Time Decremental Algorithms for Single-Source Reachability and Shortest Paths on Directed Graphs.” 46th Annual ACM Symposium on Theory of Computing, 674–683, Association for Computing Machinery, 2014, doi:10.1145/2591796.2591869."},"extern":"1","conference":{"location":"New York, NY, United States","start_date":"2014-05-31","end_date":"2014-06-03","name":"STOC: Symposium on Theory of Computing"},"abstract":[{"lang":"eng","text":"We consider dynamic algorithms for maintaining Single-Source Reachability (SSR) and approximate Single-Source Shortest Paths (SSSP) on n-node m-edge directed graphs under edge deletions (decremental algorithms). The previous fastest algorithm for SSR and SSSP goes back three decades to Even and Shiloach (JACM 1981); it has O(1) query time and O(mn) total update time (i.e., linear amortized update time if all edges are deleted). This algorithm serves as a building block for several other dynamic algorithms. The question whether its total update time can be improved is a major, long standing, open problem.\r\n\r\nIn this paper, we answer this question affirmatively. We obtain a randomized algorithm which, in a simplified form, achieves an Õ(mn0.984) expected total update time for SSR and (1 + ε)-approximate SSSP, where Õ(·) hides poly log n. We also extend our algorithm to achieve roughly the same running time for Strongly Connected Components (SCC), improving the algorithm of Roditty and Zwick (FOCS 2002), and an algorithm that improves the Õ (mn log W)-time algorithm of Bernstein (STOC 2013) for approximating SSSP on weighted directed graphs, where the edge weights are integers from 1 to W. All our algorithms have constant query time in the worst case."}],"oa":1,"external_id":{"arxiv":["1504.07959"]}},{"oa":1,"abstract":[{"text":"We present the first deterministic data structures for maintaining approximate minimum vertex cover and maximum matching in a fully dynamic graph in time per update. In particular, for minimum vertex cover we provide deterministic data structures for maintaining a (2 + ε) approximation in O(log n/ε2) amortized time per update. For maximum matching, we show how to maintain a (3 + e) approximation in O(m1/3/ε2) amortized time per update, and a (4 + ε) approximation in O(m1/3/ε2) worst-case time per update. Our data structure for fully dynamic minimum vertex cover is essentially near-optimal and settles an open problem by Onak and Rubinfeld [13].","lang":"eng"}],"page":"785-804","external_id":{"arxiv":["1412.1318"]},"year":"2014","publication_identifier":{"eisbn":["978-1-61197-373-0"],"isbn":["978-1-61197-374-7"]},"language":[{"iso":"eng"}],"arxiv":1,"doi":"10.1137/1.9781611973730.54","citation":{"apa":"Bhattacharya, S., Henzinger, M. H., & Italiano, G. F. (2014). Deterministic fully dynamic data structures for vertex cover and matching. In 26th Annual ACM-SIAM Symposium on Discrete Algorithms (pp. 785–804). San Diego, CA, United States: Society for Industrial and Applied Mathematics. https://doi.org/10.1137/1.9781611973730.54","short":"S. Bhattacharya, M.H. Henzinger, G.F. Italiano, in:, 26th Annual ACM-SIAM Symposium on Discrete Algorithms, Society for Industrial and Applied Mathematics, 2014, pp. 785–804.","chicago":"Bhattacharya, Sayan, Monika H Henzinger, and Giuseppe F. Italiano. “Deterministic Fully Dynamic Data Structures for Vertex Cover and Matching.” In 26th Annual ACM-SIAM Symposium on Discrete Algorithms, 785–804. Society for Industrial and Applied Mathematics, 2014. https://doi.org/10.1137/1.9781611973730.54.","ista":"Bhattacharya S, Henzinger MH, Italiano GF. 2014. Deterministic fully dynamic data structures for vertex cover and matching. 26th Annual ACM-SIAM Symposium on Discrete Algorithms. SODA: Symposium on Discrete Algorithms, 785–804.","ieee":"S. Bhattacharya, M. H. Henzinger, and G. F. Italiano, “Deterministic fully dynamic data structures for vertex cover and matching,” in 26th Annual ACM-SIAM Symposium on Discrete Algorithms, San Diego, CA, United States, 2014, pp. 785–804.","mla":"Bhattacharya, Sayan, et al. “Deterministic Fully Dynamic Data Structures for Vertex Cover and Matching.” 26th Annual ACM-SIAM Symposium on Discrete Algorithms, Society for Industrial and Applied Mathematics, 2014, pp. 785–804, doi:10.1137/1.9781611973730.54.","ama":"Bhattacharya S, Henzinger MH, Italiano GF. Deterministic fully dynamic data structures for vertex cover and matching. In: 26th Annual ACM-SIAM Symposium on Discrete Algorithms. Society for Industrial and Applied Mathematics; 2014:785-804. doi:10.1137/1.9781611973730.54"},"quality_controlled":"1","extern":"1","related_material":{"record":[{"status":"public","id":"11890","relation":"later_version"}]},"conference":{"name":"SODA: Symposium on Discrete Algorithms","end_date":"2015-01-06","start_date":"2015-01-04","location":"San Diego, CA, United States"},"month":"01","date_published":"2014-01-01T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","publisher":"Society for Industrial and Applied Mathematics","date_updated":"2023-02-21T16:32:06Z","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1412.1318"}],"scopus_import":"1","day":"01","title":"Deterministic fully dynamic data structures for vertex cover and matching","status":"public","oa_version":"Preprint","date_created":"2022-08-16T12:36:42Z","_id":"11875","type":"conference","article_processing_charge":"No","publication":"26th Annual ACM-SIAM Symposium on Discrete Algorithms","author":[{"full_name":"Bhattacharya, Sayan","first_name":"Sayan","last_name":"Bhattacharya"},{"orcid":"0000-0002-5008-6530","full_name":"Henzinger, Monika H","last_name":"Henzinger","id":"540c9bbd-f2de-11ec-812d-d04a5be85630","first_name":"Monika H"},{"last_name":"Italiano","first_name":"Giuseppe F.","full_name":"Italiano, Giuseppe F."}]},{"scopus_import":"1","page":"1053-1072","main_file_link":[{"url":"https://doi.org/10.1137/1.9781611973402.79","open_access":"1"}],"date_updated":"2023-02-17T11:58:42Z","publisher":"Society for Industrial and Applied Mathematics","publication_status":"published","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2014-01-01T00:00:00Z","month":"01","abstract":[{"text":"We study dynamic (1 + ∊)-approximation algorithms for the single-source shortest paths problem in an unweighted undirected n-node m-edge graph under edge deletions. The fastest algorithm for this problem is an algorithm with O(n2+o(1)) total update time and constant query time by Bernstein and Roditty (SODA 2011). In this paper, we improve the total update time to O(n1.8+o(1) + m1+o(1)) while keeping the query time constant. This running time is essentially tight when m = Ω(n1.8) since we need Ω(m) time even in the static setting. For smaller values of m, the running time of our algorithm is subquadratic, and is the first that breaks through the quadratic time barrier.\r\n\r\nIn obtaining this result, we develop a fast algorithm for what we call center cover data structure. We also make non-trivial extensions to our previous techniques called lazy-update and monotone Even-Shiloach trees (ICALP 2013 and FOCS 2013). As by-products of our new techniques, we obtain two new results for the decremental all-pairs shortest-paths problem. Our first result is the first approximation algorithm whose total update time is faster than Õ(mn) for all values of m. Our second result is a new trade-off between the total update time and the additive approximation guarantee.","lang":"eng"}],"oa":1,"conference":{"location":"Portland, OR, United States","end_date":"2014-01-07","start_date":"2014-01-05","name":"SODA: Symposium on Discrete Algorithms"},"author":[{"orcid":"0000-0002-5008-6530","full_name":"Henzinger, Monika H","last_name":"Henzinger","id":"540c9bbd-f2de-11ec-812d-d04a5be85630","first_name":"Monika H"},{"last_name":"Krinninger","first_name":"Sebastian","full_name":"Krinninger, Sebastian"},{"first_name":"Danupon","last_name":"Nanongkai","full_name":"Nanongkai, Danupon"}],"extern":"1","publication":"25th Annual ACM-SIAM Symposium on Discrete Algorithms","type":"conference","_id":"11876","article_processing_charge":"No","oa_version":"Published Version","date_created":"2022-08-16T12:58:31Z","quality_controlled":"1","citation":{"short":"M.H. Henzinger, S. Krinninger, D. Nanongkai, in:, 25th Annual ACM-SIAM Symposium on Discrete Algorithms, Society for Industrial and Applied Mathematics, 2014, pp. 1053–1072.","chicago":"Henzinger, Monika H, Sebastian Krinninger, and Danupon Nanongkai. “A Subquadratic-Time Algorithm for Decremental Single-Source Shortest Paths.” In 25th Annual ACM-SIAM Symposium on Discrete Algorithms, 1053–72. Society for Industrial and Applied Mathematics, 2014. https://doi.org/10.1137/1.9781611973402.79.","apa":"Henzinger, M. H., Krinninger, S., & Nanongkai, D. (2014). A subquadratic-time algorithm for decremental single-source shortest paths. In 25th Annual ACM-SIAM Symposium on Discrete Algorithms (pp. 1053–1072). Portland, OR, United States: Society for Industrial and Applied Mathematics. https://doi.org/10.1137/1.9781611973402.79","mla":"Henzinger, Monika H., et al. “A Subquadratic-Time Algorithm for Decremental Single-Source Shortest Paths.” 25th Annual ACM-SIAM Symposium on Discrete Algorithms, Society for Industrial and Applied Mathematics, 2014, pp. 1053–72, doi:10.1137/1.9781611973402.79.","ieee":"M. H. Henzinger, S. Krinninger, and D. Nanongkai, “A subquadratic-time algorithm for decremental single-source shortest paths,” in 25th Annual ACM-SIAM Symposium on Discrete Algorithms, Portland, OR, United States, 2014, pp. 1053–1072.","ista":"Henzinger MH, Krinninger S, Nanongkai D. 2014. A subquadratic-time algorithm for decremental single-source shortest paths. 25th Annual ACM-SIAM Symposium on Discrete Algorithms. SODA: Symposium on Discrete Algorithms, 1053–1072.","ama":"Henzinger MH, Krinninger S, Nanongkai D. A subquadratic-time algorithm for decremental single-source shortest paths. In: 25th Annual ACM-SIAM Symposium on Discrete Algorithms. Society for Industrial and Applied Mathematics; 2014:1053-1072. doi:10.1137/1.9781611973402.79"},"doi":"10.1137/1.9781611973402.79","status":"public","title":"A subquadratic-time algorithm for decremental single-source shortest paths","language":[{"iso":"eng"}],"publication_identifier":{"isbn":["978-1-61197-338-9"],"eisbn":["978-1-61197-340-2"]},"year":"2014","day":"01"},{"external_id":{"arxiv":["1309.2578"]},"oa":1,"abstract":[{"lang":"eng","text":"Observations of flowing granular matter have suggested that same-material tribocharging depends on particle size, typically rendering large grains positive and small ones negative. Models assuming the transfer of trapped electrons can account for this trend, but have not been validated. Tracking individual grains in an electric field, we show quantitatively that charge is transferred based on size between materially identical grains. However, the surface density of trapped electrons, measured independently by thermoluminescence techniques, is orders of magnitude too small to account for the scale of charge transferred. This reveals that trapped electrons are not a necessary ingredient for same-material tribocharging."}],"acknowledgement":"This work was supported by the NSF through DMR-1309611. Access to the shared experimental facilities provided by the NSF-supported Chicago MRSEC (DMR-0820054) is gratefully acknowledged. S. L. F. and J. L. P. acknowledge funding from UIC NSF Grants No. 0850830 and No. 0602308. S. R. W. acknowledges support from a University of Chicago Millikan Fellowship and from Mrs. Joan Winstein through the Winstein Prize for Instrumentation.","citation":{"mla":"Waitukaitis, Scott R., et al. “Size-Dependent Same-Material Tribocharging in Insulating Grains.” APS Physics, Physical Review Letters, vol. 112, no. 21, 218001, American Physical Society, 2014, doi:10.1103/PhysRevLett.112.218001.","ista":"Waitukaitis SR, Lee V, Pierson J, Forman S, Jaeger H. 2014. Size-dependent same-material tribocharging in insulating grains. APS Physics, Physical Review Letters. 112(21), 218001.","ieee":"S. R. Waitukaitis, V. Lee, J. Pierson, S. Forman, and H. Jaeger, “Size-dependent same-material tribocharging in insulating grains,” APS Physics, Physical Review Letters, vol. 112, no. 21. American Physical Society, 2014.","short":"S.R. Waitukaitis, V. Lee, J. Pierson, S. Forman, H. Jaeger, APS Physics, Physical Review Letters 112 (2014).","chicago":"Waitukaitis, Scott R, Victor Lee, James Pierson, Steven Forman, and Heinrich Jaeger. “Size-Dependent Same-Material Tribocharging in Insulating Grains.” APS Physics, Physical Review Letters. American Physical Society, 2014. https://doi.org/10.1103/PhysRevLett.112.218001.","apa":"Waitukaitis, S. R., Lee, V., Pierson, J., Forman, S., & Jaeger, H. (2014). Size-dependent same-material tribocharging in insulating grains. APS Physics, Physical Review Letters. American Physical Society. https://doi.org/10.1103/PhysRevLett.112.218001","ama":"Waitukaitis SR, Lee V, Pierson J, Forman S, Jaeger H. Size-dependent same-material tribocharging in insulating grains. APS Physics, Physical Review Letters. 2014;112(21). doi:10.1103/PhysRevLett.112.218001"},"doi":"10.1103/PhysRevLett.112.218001","quality_controlled":"1","extern":"1","arxiv":1,"intvolume":" 112","year":"2014","language":[{"iso":"eng"}],"main_file_link":[{"url":"https://arxiv.org/abs/1309.2578","open_access":"1"}],"user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","publication_status":"published","publisher":"American Physical Society","date_updated":"2021-01-12T06:48:58Z","publist_id":"7935","month":"05","date_published":"2014-05-30T00:00:00Z","author":[{"full_name":"Waitukaitis, Scott R","orcid":"0000-0002-2299-3176","id":"3A1FFC16-F248-11E8-B48F-1D18A9856A87","first_name":"Scott R","last_name":"Waitukaitis"},{"last_name":"Lee","first_name":"Victor","full_name":"Lee, Victor"},{"last_name":"Pierson","first_name":"James","full_name":"Pierson, James"},{"first_name":"Steven","last_name":"Forman","full_name":"Forman, Steven"},{"first_name":"Heinrich","last_name":"Jaeger","full_name":"Jaeger, Heinrich"}],"oa_version":"Submitted Version","date_created":"2018-12-11T11:44:44Z","_id":"119","issue":"21","type":"journal_article","publication":"APS Physics, Physical Review Letters","volume":112,"title":"Size-dependent same-material tribocharging in insulating grains","article_number":"218001","status":"public","day":"30"},{"publication_identifier":{"issn":["1864-5631"],"eissn":["1864-564X"]},"language":[{"iso":"eng"}],"year":"2014","pmid":1,"intvolume":" 7","extern":"1","citation":{"ama":"Moghaddam MM, Pieber B, Glasnov T, Kappe CO. Immobilized iron oxide nanoparticles as stable and reusable catalysts for hydrazine-mediated nitro reductions in continuous flow. ChemSusChem. 2014;7(11):3122-3131. doi:10.1002/cssc.201402455","mla":"Moghaddam, Mojtaba Mirhosseini, et al. “Immobilized Iron Oxide Nanoparticles as Stable and Reusable Catalysts for Hydrazine-Mediated Nitro Reductions in Continuous Flow.” ChemSusChem, vol. 7, no. 11, Wiley, 2014, pp. 3122–31, doi:10.1002/cssc.201402455.","ieee":"M. M. Moghaddam, B. Pieber, T. Glasnov, and C. O. Kappe, “Immobilized iron oxide nanoparticles as stable and reusable catalysts for hydrazine-mediated nitro reductions in continuous flow,” ChemSusChem, vol. 7, no. 11. Wiley, pp. 3122–3131, 2014.","ista":"Moghaddam MM, Pieber B, Glasnov T, Kappe CO. 2014. Immobilized iron oxide nanoparticles as stable and reusable catalysts for hydrazine-mediated nitro reductions in continuous flow. ChemSusChem. 7(11), 3122–3131.","chicago":"Moghaddam, Mojtaba Mirhosseini, Bartholomäus Pieber, Toma Glasnov, and C. Oliver Kappe. “Immobilized Iron Oxide Nanoparticles as Stable and Reusable Catalysts for Hydrazine-Mediated Nitro Reductions in Continuous Flow.” ChemSusChem. Wiley, 2014. https://doi.org/10.1002/cssc.201402455.","short":"M.M. Moghaddam, B. Pieber, T. Glasnov, C.O. Kappe, ChemSusChem 7 (2014) 3122–3131.","apa":"Moghaddam, M. M., Pieber, B., Glasnov, T., & Kappe, C. O. (2014). Immobilized iron oxide nanoparticles as stable and reusable catalysts for hydrazine-mediated nitro reductions in continuous flow. ChemSusChem. Wiley. https://doi.org/10.1002/cssc.201402455"},"doi":"10.1002/cssc.201402455","quality_controlled":"1","abstract":[{"lang":"eng","text":"An experimentally easy to perform method for the generation of alumina-supported Fe3O4 nanoparticles [(6±1) nm size, 0.67 wt %]and the use of this material in hydrazine-mediated heterogeneously catalyzed reductions of nitroarenes to anilines under batch and continuous-flow conditions is presented. The bench-stable, reusable nano-Fe3O4@Al2O3 catalyst can selectively reduce functionalized nitroarenes at 1 mol % catalyst loading by using a 20 mol % excess of hydrazine hydrate in an elevated temperature regime (150 °C, reaction time 2–6 min in batch). For continuous-flow processing, the catalyst material is packed into dedicated cartridges and used in a commercially available high-temperature/-pressure flow device. In continuous mode, reaction times can be reduced to less than 1 min at 150 °C (30 bar back pressure) in a highly intensified process. The nano-Fe3O4@Al2O3 catalyst demonstrated stable reduction of nitrobenzene (0.5 M in MeOH) for more than 10 h on stream at a productivity of 30 mmol h−1 (0.72 mol per day). Importantly, virtually no leaching of the catalytically active material could be observed by inductively coupled plasma MS monitoring."}],"external_id":{"pmid":["25209099"]},"page":"3122-3131","day":"01","status":"public","volume":7,"title":"Immobilized iron oxide nanoparticles as stable and reusable catalysts for hydrazine-mediated nitro reductions in continuous flow","issue":"11","_id":"11967","article_processing_charge":"No","type":"journal_article","publication":"ChemSusChem","date_created":"2022-08-25T08:36:54Z","oa_version":"None","author":[{"last_name":"Moghaddam","first_name":"Mojtaba Mirhosseini","full_name":"Moghaddam, Mojtaba Mirhosseini"},{"full_name":"Pieber, Bartholomäus","orcid":"0000-0001-8689-388X","first_name":"Bartholomäus","id":"93e5e5b2-0da6-11ed-8a41-af589a024726","last_name":"Pieber"},{"first_name":"Toma","last_name":"Glasnov","full_name":"Glasnov, Toma"},{"first_name":"C. Oliver","last_name":"Kappe","full_name":"Kappe, C. Oliver"}],"month":"11","date_published":"2014-11-01T00:00:00Z","article_type":"original","publisher":"Wiley","date_updated":"2023-02-21T10:09:42Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","scopus_import":"1"},{"page":"P729-739","external_id":{"pmid":["24960695"]},"abstract":[{"text":"Membrane phospholipids typically contain fatty acids (FAs) of 16 and 18 carbon atoms. This particular chain length is evolutionarily highly conserved and presumably provides maximum stability and dynamic properties to biological membranes in response to nutritional or environmental cues. Here, we show that the relative proportion of C16 versus C18 FAs is regulated by the activity of acetyl-CoA carboxylase (Acc1), the first and rate-limiting enzyme of FA de novo synthesis. Acc1 activity is attenuated by AMPK/Snf1-dependent phosphorylation, which is required to maintain an appropriate acyl-chain length distribution. Moreover, we find that the transcriptional repressor Opi1 preferentially binds to C16 over C18 phosphatidic acid (PA) species: thus, C16-chain containing PA sequesters Opi1 more effectively to the ER, enabling AMPK/Snf1 control of PA acyl-chain length to determine the degree of derepression of Opi1 target genes. These findings reveal an unexpected regulatory link between the major energy-sensing kinase, membrane lipid composition, and transcription.","lang":"eng"}],"oa":1,"quality_controlled":"1","citation":{"ama":"Hofbauer HF, Schopf FH, Schleifer H, et al. Regulation of gene expression through a transcriptional repressor that senses acyl-chain length in membrane phospholipids. Developmental Cell. 2014;29(6):P729-739. doi:10.1016/j.devcel.2014.04.025","ista":"Hofbauer HF, Schopf FH, Schleifer H, Knittelfelder OL, Pieber B, Rechberger GN, Wolinski H, Gaspar ML, Kappe CO, Stadlmann J, Mechtler K, Zenz A, Lohner K, Tehlivets O, Henry SA, Kohlwein SD. 2014. Regulation of gene expression through a transcriptional repressor that senses acyl-chain length in membrane phospholipids. Developmental Cell. 29(6), P729-739.","ieee":"H. F. Hofbauer et al., “Regulation of gene expression through a transcriptional repressor that senses acyl-chain length in membrane phospholipids,” Developmental Cell, vol. 29, no. 6. Elsevier, pp. P729-739, 2014.","mla":"Hofbauer, Harald F., et al. “Regulation of Gene Expression through a Transcriptional Repressor That Senses Acyl-Chain Length in Membrane Phospholipids.” Developmental Cell, vol. 29, no. 6, Elsevier, 2014, pp. P729-739, doi:10.1016/j.devcel.2014.04.025.","apa":"Hofbauer, H. F., Schopf, F. H., Schleifer, H., Knittelfelder, O. L., Pieber, B., Rechberger, G. N., … Kohlwein, S. D. (2014). Regulation of gene expression through a transcriptional repressor that senses acyl-chain length in membrane phospholipids. Developmental Cell. Elsevier. https://doi.org/10.1016/j.devcel.2014.04.025","chicago":"Hofbauer, Harald F., Florian H. Schopf, Hannes Schleifer, Oskar L. Knittelfelder, Bartholomäus Pieber, Gerald N. Rechberger, Heimo Wolinski, et al. “Regulation of Gene Expression through a Transcriptional Repressor That Senses Acyl-Chain Length in Membrane Phospholipids.” Developmental Cell. Elsevier, 2014. https://doi.org/10.1016/j.devcel.2014.04.025.","short":"H.F. Hofbauer, F.H. Schopf, H. Schleifer, O.L. Knittelfelder, B. Pieber, G.N. Rechberger, H. Wolinski, M.L. Gaspar, C.O. Kappe, J. Stadlmann, K. Mechtler, A. Zenz, K. Lohner, O. Tehlivets, S.A. Henry, S.D. Kohlwein, Developmental Cell 29 (2014) P729-739."},"doi":"10.1016/j.devcel.2014.04.025","extern":"1","intvolume":" 29","pmid":1,"year":"2014","language":[{"iso":"eng"}],"publication_identifier":{"eissn":["1878-1551"],"issn":["1534-5807"]},"scopus_import":"1","main_file_link":[{"url":"https://doi.org/10.1016/j.devcel.2014.04.025","open_access":"1"}],"publication_status":"published","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2023-02-21T10:09:45Z","publisher":"Elsevier","article_type":"original","month":"06","date_published":"2014-06-23T00:00:00Z","author":[{"full_name":"Hofbauer, Harald F.","last_name":"Hofbauer","first_name":"Harald F."},{"full_name":"Schopf, Florian H.","last_name":"Schopf","first_name":"Florian H."},{"full_name":"Schleifer, Hannes","last_name":"Schleifer","first_name":"Hannes"},{"full_name":"Knittelfelder, Oskar L.","last_name":"Knittelfelder","first_name":"Oskar L."},{"first_name":"Bartholomäus","id":"93e5e5b2-0da6-11ed-8a41-af589a024726","last_name":"Pieber","orcid":"0000-0001-8689-388X","full_name":"Pieber, Bartholomäus"},{"full_name":"Rechberger, Gerald N.","first_name":"Gerald N.","last_name":"Rechberger"},{"full_name":"Wolinski, Heimo","last_name":"Wolinski","first_name":"Heimo"},{"full_name":"Gaspar, Maria L.","first_name":"Maria L.","last_name":"Gaspar"},{"last_name":"Kappe","first_name":"C. Oliver","full_name":"Kappe, C. Oliver"},{"first_name":"Johannes","last_name":"Stadlmann","full_name":"Stadlmann, Johannes"},{"first_name":"Karl","last_name":"Mechtler","full_name":"Mechtler, Karl"},{"full_name":"Zenz, Alexandra","first_name":"Alexandra","last_name":"Zenz"},{"first_name":"Karl","last_name":"Lohner","full_name":"Lohner, Karl"},{"full_name":"Tehlivets, Oksana","last_name":"Tehlivets","first_name":"Oksana"},{"first_name":"Susan A.","last_name":"Henry","full_name":"Henry, Susan A."},{"full_name":"Kohlwein, Sepp D.","last_name":"Kohlwein","first_name":"Sepp D."}],"date_created":"2022-08-25T08:42:42Z","oa_version":"Published Version","publication":"Developmental Cell","type":"journal_article","_id":"11968","article_processing_charge":"No","issue":"6","title":"Regulation of gene expression through a transcriptional repressor that senses acyl-chain length in membrane phospholipids","volume":29,"status":"public","day":"23"},{"author":[{"last_name":"Pieber","first_name":"Bartholomäus","id":"93e5e5b2-0da6-11ed-8a41-af589a024726","orcid":"0000-0001-8689-388X","full_name":"Pieber, Bartholomäus"},{"full_name":"Glasnov, Toma","last_name":"Glasnov","first_name":"Toma"},{"first_name":"C. O.","last_name":"Kappe","full_name":"Kappe, C. O."}],"extern":"1","publication":"RSC Advances","_id":"11987","type":"journal_article","article_processing_charge":"No","issue":"26","oa_version":"None","quality_controlled":"1","date_created":"2022-08-25T11:48:19Z","doi":"10.1039/c4ra01442a","citation":{"ama":"Pieber B, Glasnov T, Kappe CO. Flash carboxylation: Fast lithiation–carboxylation sequence at room temperature in continuous flow. RSC Advances. 2014;4(26). doi:10.1039/c4ra01442a","apa":"Pieber, B., Glasnov, T., & Kappe, C. O. (2014). Flash carboxylation: Fast lithiation–carboxylation sequence at room temperature in continuous flow. RSC Advances. Royal Society of Chemistry. https://doi.org/10.1039/c4ra01442a","short":"B. Pieber, T. Glasnov, C.O. Kappe, RSC Advances 4 (2014).","chicago":"Pieber, Bartholomäus, Toma Glasnov, and C. O. Kappe. “Flash Carboxylation: Fast Lithiation–Carboxylation Sequence at Room Temperature in Continuous Flow.” RSC Advances. Royal Society of Chemistry, 2014. https://doi.org/10.1039/c4ra01442a.","ieee":"B. Pieber, T. Glasnov, and C. O. Kappe, “Flash carboxylation: Fast lithiation–carboxylation sequence at room temperature in continuous flow,” RSC Advances, vol. 4, no. 26. Royal Society of Chemistry, 2014.","ista":"Pieber B, Glasnov T, Kappe CO. 2014. Flash carboxylation: Fast lithiation–carboxylation sequence at room temperature in continuous flow. RSC Advances. 4(26), 13430.","mla":"Pieber, Bartholomäus, et al. “Flash Carboxylation: Fast Lithiation–Carboxylation Sequence at Room Temperature in Continuous Flow.” RSC Advances, vol. 4, no. 26, 13430, Royal Society of Chemistry, 2014, doi:10.1039/c4ra01442a."},"intvolume":" 4","status":"public","article_number":"13430","volume":4,"title":"Flash carboxylation: Fast lithiation–carboxylation sequence at room temperature in continuous flow","publication_identifier":{"eissn":["2046-2069"]},"language":[{"iso":"eng"}],"day":"03","year":"2014","scopus_import":"1","date_updated":"2023-02-21T10:10:31Z","publisher":"Royal Society of Chemistry","publication_status":"published","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_type":"letter_note","date_published":"2014-03-03T00:00:00Z","month":"03","abstract":[{"text":"A method for the direct lithiation of terminal alkynes and heterocycles with subsequent carboxylation in a continuous flow format was developed. This method provides carboxylic acids at ambient conditions within less than five seconds with only little excess of the organometallic base and CO2.","lang":"eng"}]},{"date_published":"2013-09-06T00:00:00Z","month":"09","article_type":"original","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","publisher":"Wiley","date_updated":"2023-02-24T08:48:40Z","scopus_import":"1","day":"06","title":"An evaluation of approaches for modelling hydrological processes in high-elevation, glacierized Andean watersheds","volume":28,"status":"public","oa_version":"None","date_created":"2023-02-20T08:16:39Z","_id":"12633","type":"journal_article","article_processing_charge":"No","issue":"23","publication":"Hydrological Processes","author":[{"full_name":"Ragettli, S.","last_name":"Ragettli","first_name":"S."},{"last_name":"Cortés","first_name":"G.","full_name":"Cortés, G."},{"first_name":"J.","last_name":"McPhee","full_name":"McPhee, J."},{"id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70","first_name":"Francesca","last_name":"Pellicciotti","full_name":"Pellicciotti, Francesca"}],"abstract":[{"text":"We use two hydrological models of varying complexity to study the Juncal River Basin in the Central Andes of Chile with the aim to understand the degree of conceptualization and the spatial structure that are needed to model present and future streamflows. We use a conceptual semi-distributed model based on elevation bands [Water Evaluation and Planning (WEAP)], frequently used for water management, and a physically oriented, fully distributed model [Topographic Kinematic Wave Approximation and Integration ETH Zurich (TOPKAPI-ETH)] developed for research purposes mainly. We evaluate the ability of the two models to reproduce the key hydrological processes in the basin with emphasis on snow accumulation and melt, streamflow and the relationships between internal processes. Both models are capable of reproducing observed runoff and the evolution of Moderate-resolution Imaging Spectroradiometer snow cover adequately. In spite of WEAP's simple and conceptual approach for modelling snowmelt and its lack of glacier representation and snow gravitational redistribution as well as a proper routing algorithm, this model can reproduce historical data with a similar goodness of fit as the more complex TOPKAPI-ETH. We show that the performance of both models can be improved by using measured precipitation gradients of higher temporal resolution. In contrast to the good performance of the conceptual model for the present climate, however, we demonstrate that the simplifications in WEAP lead to error compensation, which results in different predictions in simulated melt and runoff for a potentially warmer future climate. TOPKAPI-ETH, using a more physical representation of processes, depends less on calibration and thus is less subject to a compensation of errors through different model components. Our results show that data obtained locally in ad hoc short-term field campaigns are needed to complement data extrapolated from long-term records for simulating changes in the water cycle of high-elevation catchments but that these data can only be efficiently used by a model applying a spatially distributed physical representation of hydrological processes.","lang":"eng"}],"keyword":["Water Science and Technology"],"page":"5674-5695","year":"2013","language":[{"iso":"eng"}],"publication_identifier":{"issn":["0885-6087"]},"intvolume":" 28","doi":"10.1002/hyp.10055","citation":{"ama":"Ragettli S, Cortés G, McPhee J, Pellicciotti F. An evaluation of approaches for modelling hydrological processes in high-elevation, glacierized Andean watersheds. Hydrological Processes. 2013;28(23):5674-5695. doi:10.1002/hyp.10055","chicago":"Ragettli, S., G. Cortés, J. McPhee, and Francesca Pellicciotti. “An Evaluation of Approaches for Modelling Hydrological Processes in High-Elevation, Glacierized Andean Watersheds.” Hydrological Processes. Wiley, 2013. https://doi.org/10.1002/hyp.10055.","short":"S. Ragettli, G. Cortés, J. McPhee, F. Pellicciotti, Hydrological Processes 28 (2013) 5674–5695.","apa":"Ragettli, S., Cortés, G., McPhee, J., & Pellicciotti, F. (2013). An evaluation of approaches for modelling hydrological processes in high-elevation, glacierized Andean watersheds. Hydrological Processes. Wiley. https://doi.org/10.1002/hyp.10055","mla":"Ragettli, S., et al. “An Evaluation of Approaches for Modelling Hydrological Processes in High-Elevation, Glacierized Andean Watersheds.” Hydrological Processes, vol. 28, no. 23, Wiley, 2013, pp. 5674–95, doi:10.1002/hyp.10055.","ieee":"S. Ragettli, G. Cortés, J. McPhee, and F. Pellicciotti, “An evaluation of approaches for modelling hydrological processes in high-elevation, glacierized Andean watersheds,” Hydrological Processes, vol. 28, no. 23. Wiley, pp. 5674–5695, 2013.","ista":"Ragettli S, Cortés G, McPhee J, Pellicciotti F. 2013. An evaluation of approaches for modelling hydrological processes in high-elevation, glacierized Andean watersheds. Hydrological Processes. 28(23), 5674–5695."},"quality_controlled":"1","extern":"1"},{"publication_identifier":{"issn":["1607-7938"]},"language":[{"iso":"eng"}],"year":"2013","intvolume":" 17","extern":"1","citation":{"mla":"Lutz, A. F., et al. “Comparison of Climate Change Signals in CMIP3 and CMIP5 Multi-Model Ensembles and Implications for Central Asian Glaciers.” Hydrology and Earth System Sciences, vol. 17, no. 9, Copernicus GmbH, 2013, pp. 3661–77, doi:10.5194/hess-17-3661-2013.","ista":"Lutz AF, Immerzeel WW, Gobiet A, Pellicciotti F, Bierkens MFP. 2013. Comparison of climate change signals in CMIP3 and CMIP5 multi-model ensembles and implications for Central Asian glaciers. Hydrology and Earth System Sciences. 17(9), 3661–3677.","ieee":"A. F. Lutz, W. W. Immerzeel, A. Gobiet, F. Pellicciotti, and M. F. P. Bierkens, “Comparison of climate change signals in CMIP3 and CMIP5 multi-model ensembles and implications for Central Asian glaciers,” Hydrology and Earth System Sciences, vol. 17, no. 9. Copernicus GmbH, pp. 3661–3677, 2013.","chicago":"Lutz, A. F., W. W. Immerzeel, A. Gobiet, Francesca Pellicciotti, and M. F. P. Bierkens. “Comparison of Climate Change Signals in CMIP3 and CMIP5 Multi-Model Ensembles and Implications for Central Asian Glaciers.” Hydrology and Earth System Sciences. Copernicus GmbH, 2013. https://doi.org/10.5194/hess-17-3661-2013.","short":"A.F. Lutz, W.W. Immerzeel, A. Gobiet, F. Pellicciotti, M.F.P. Bierkens, Hydrology and Earth System Sciences 17 (2013) 3661–3677.","apa":"Lutz, A. F., Immerzeel, W. W., Gobiet, A., Pellicciotti, F., & Bierkens, M. F. P. (2013). Comparison of climate change signals in CMIP3 and CMIP5 multi-model ensembles and implications for Central Asian glaciers. Hydrology and Earth System Sciences. Copernicus GmbH. https://doi.org/10.5194/hess-17-3661-2013","ama":"Lutz AF, Immerzeel WW, Gobiet A, Pellicciotti F, Bierkens MFP. Comparison of climate change signals in CMIP3 and CMIP5 multi-model ensembles and implications for Central Asian glaciers. Hydrology and Earth System Sciences. 2013;17(9):3661-3677. doi:10.5194/hess-17-3661-2013"},"doi":"10.5194/hess-17-3661-2013","quality_controlled":"1","oa":1,"abstract":[{"text":"Central Asian water resources largely depend on melt water generated in the Pamir and Tien Shan mountain ranges. To estimate future water availability in this region, it is necessary to use climate projections to estimate the future glacier extent and volume. In this study, we evaluate the impact of uncertainty in climate change projections on the future glacier extent in the Amu and Syr Darya river basins. To this end we use the latest climate change projections generated for the upcoming IPCC report (CMIP5) and, for comparison, projections used in the fourth IPCC assessment (CMIP3). With these projections we force a regionalized glacier mass balance model, and estimate changes in the basins' glacier extent as a function of the glacier size distribution in the basins and projected temperature and precipitation. This glacier mass balance model is specifically developed for implementation in large scale hydrological models, where the spatial resolution does not allow for simulating individual glaciers and data scarcity is an issue. Although the CMIP5 ensemble results in greater regional warming than the CMIP3 ensemble and the range in projections for temperature as well as precipitation is wider for the CMIP5 than for the CMIP3, the spread in projections of future glacier extent in Central Asia is similar for both ensembles. This is because differences in temperature rise are small during periods of maximum melt (July–September) while differences in precipitation change are small during the period of maximum accumulation (October–February). However, the model uncertainty due to parameter uncertainty is high, and has roughly the same importance as uncertainty in the climate projections. Uncertainty about the size of the decline in glacier extent remains large, making estimates of future Central Asian glacier evolution and downstream water availability uncertain.","lang":"eng"}],"keyword":["General Earth and Planetary Sciences","General Engineering","General Environmental Science"],"page":"3661-3677","day":"01","status":"public","volume":17,"title":"Comparison of climate change signals in CMIP3 and CMIP5 multi-model ensembles and implications for Central Asian glaciers","issue":"9","_id":"12638","article_processing_charge":"No","type":"journal_article","publication":"Hydrology and Earth System Sciences","oa_version":"Published Version","date_created":"2023-02-20T08:17:05Z","author":[{"first_name":"A. F.","last_name":"Lutz","full_name":"Lutz, A. F."},{"full_name":"Immerzeel, W. W.","last_name":"Immerzeel","first_name":"W. W."},{"full_name":"Gobiet, A.","first_name":"A.","last_name":"Gobiet"},{"full_name":"Pellicciotti, Francesca","last_name":"Pellicciotti","first_name":"Francesca","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70"},{"full_name":"Bierkens, M. F. P.","first_name":"M. F. P.","last_name":"Bierkens"}],"month":"09","date_published":"2013-09-01T00:00:00Z","article_type":"original","publisher":"Copernicus GmbH","date_updated":"2023-02-24T08:19:48Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","main_file_link":[{"url":"https://doi.org/10.5194/hess-17-3661-2013","open_access":"1"}],"scopus_import":"1"},{"day":"01","status":"public","title":"Sources of uncertainty in modeling the glaciohydrological response of a Karakoram watershed to climate change","volume":49,"publication":"Water Resources Research","_id":"12639","type":"journal_article","article_processing_charge":"No","issue":"9","date_created":"2023-02-20T08:17:12Z","oa_version":"Published Version","author":[{"first_name":"S.","last_name":"Ragettli","full_name":"Ragettli, S."},{"last_name":"Pellicciotti","first_name":"Francesca","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70","full_name":"Pellicciotti, Francesca"},{"full_name":"Bordoy, R.","first_name":"R.","last_name":"Bordoy"},{"first_name":"W. W.","last_name":"Immerzeel","full_name":"Immerzeel, W. W."}],"article_type":"original","date_published":"2013-03-01T00:00:00Z","month":"03","date_updated":"2023-02-24T08:16:19Z","publisher":"American Geophysical Union","publication_status":"published","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","main_file_link":[{"url":"https://doi.org/10.1002/wrcr.20450","open_access":"1"}],"scopus_import":"1","language":[{"iso":"eng"}],"publication_identifier":{"issn":["0043-1397"]},"year":"2013","intvolume":" 49","extern":"1","quality_controlled":"1","doi":"10.1002/wrcr.20450","citation":{"ama":"Ragettli S, Pellicciotti F, Bordoy R, Immerzeel WW. Sources of uncertainty in modeling the glaciohydrological response of a Karakoram watershed to climate change. Water Resources Research. 2013;49(9):6048-6066. doi:10.1002/wrcr.20450","ieee":"S. Ragettli, F. Pellicciotti, R. Bordoy, and W. W. Immerzeel, “Sources of uncertainty in modeling the glaciohydrological response of a Karakoram watershed to climate change,” Water Resources Research, vol. 49, no. 9. American Geophysical Union, pp. 6048–6066, 2013.","ista":"Ragettli S, Pellicciotti F, Bordoy R, Immerzeel WW. 2013. Sources of uncertainty in modeling the glaciohydrological response of a Karakoram watershed to climate change. Water Resources Research. 49(9), 6048–6066.","mla":"Ragettli, S., et al. “Sources of Uncertainty in Modeling the Glaciohydrological Response of a Karakoram Watershed to Climate Change.” Water Resources Research, vol. 49, no. 9, American Geophysical Union, 2013, pp. 6048–66, doi:10.1002/wrcr.20450.","apa":"Ragettli, S., Pellicciotti, F., Bordoy, R., & Immerzeel, W. W. (2013). Sources of uncertainty in modeling the glaciohydrological response of a Karakoram watershed to climate change. Water Resources Research. American Geophysical Union. https://doi.org/10.1002/wrcr.20450","chicago":"Ragettli, S., Francesca Pellicciotti, R. Bordoy, and W. W. Immerzeel. “Sources of Uncertainty in Modeling the Glaciohydrological Response of a Karakoram Watershed to Climate Change.” Water Resources Research. American Geophysical Union, 2013. https://doi.org/10.1002/wrcr.20450.","short":"S. Ragettli, F. Pellicciotti, R. Bordoy, W.W. Immerzeel, Water Resources Research 49 (2013) 6048–6066."},"keyword":["Water Science and Technology"],"abstract":[{"lang":"eng","text":"In the headwater catchments of the main Asian rivers, glaciohydrological models are a useful tool to anticipate impacts of climatic changes. However, the reliability of their projections strongly depends on the quality and quantity of data that are available for parameter estimation, model calibration and validation, as well as on the accuracy of climate change projections. In this study the physically oriented, glaciohydrological model TOPKAPI-ETH is used to simulate future changes in snow, glacier, and runoff from the Hunza River Basin in northern Pakistan. Three key sources of model uncertainty in future runoff projections are compared: model parameters, climate projections, and natural climate variability. A novel approach, applicable also to ungauged catchments, is used to determine which model parameters and model components significantly affect the overall model uncertainty. We show that the model is capable of reproducing streamflow and glacier mass balances, but that all analyzed sources of uncertainty significantly affect the reliability of future projections, and that their effect is variable in time and in space. The effect of parametric uncertainty often exceeds the impact of climate uncertainty and natural climate variability, especially in heavily glacierized subcatchments. The results of the uncertainty analysis allow detailed recommendations on network design and the timing and location of field measurements, which could efficiently help to reduce model uncertainty in the future."}],"oa":1,"page":"6048-6066"},{"author":[{"first_name":"W. W.","last_name":"Immerzeel","full_name":"Immerzeel, W. W."},{"full_name":"Pellicciotti, Francesca","last_name":"Pellicciotti","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70","first_name":"Francesca"},{"full_name":"Bierkens, M. F. P.","first_name":"M. F. P.","last_name":"Bierkens"}],"oa_version":"None","date_created":"2023-02-20T08:17:17Z","article_processing_charge":"No","type":"journal_article","_id":"12640","issue":"9","publication":"Nature Geoscience","title":"Rising river flows throughout the twenty-first century in two Himalayan glacierized watersheds","volume":6,"status":"public","day":"13","scopus_import":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","publisher":"Springer Nature","date_updated":"2023-02-21T10:46:37Z","date_published":"2013-09-13T00:00:00Z","month":"09","article_type":"letter_note","citation":{"short":"W.W. Immerzeel, F. Pellicciotti, M.F.P. Bierkens, Nature Geoscience 6 (2013) 742–745.","chicago":"Immerzeel, W. W., Francesca Pellicciotti, and M. F. P. Bierkens. “Rising River Flows throughout the Twenty-First Century in Two Himalayan Glacierized Watersheds.” Nature Geoscience. Springer Nature, 2013. https://doi.org/10.1038/ngeo1896.","apa":"Immerzeel, W. W., Pellicciotti, F., & Bierkens, M. F. P. (2013). Rising river flows throughout the twenty-first century in two Himalayan glacierized watersheds. Nature Geoscience. Springer Nature. https://doi.org/10.1038/ngeo1896","mla":"Immerzeel, W. W., et al. “Rising River Flows throughout the Twenty-First Century in Two Himalayan Glacierized Watersheds.” Nature Geoscience, vol. 6, no. 9, Springer Nature, 2013, pp. 742–45, doi:10.1038/ngeo1896.","ieee":"W. W. Immerzeel, F. Pellicciotti, and M. F. P. Bierkens, “Rising river flows throughout the twenty-first century in two Himalayan glacierized watersheds,” Nature Geoscience, vol. 6, no. 9. Springer Nature, pp. 742–745, 2013.","ista":"Immerzeel WW, Pellicciotti F, Bierkens MFP. 2013. Rising river flows throughout the twenty-first century in two Himalayan glacierized watersheds. Nature Geoscience. 6(9), 742–745.","ama":"Immerzeel WW, Pellicciotti F, Bierkens MFP. Rising river flows throughout the twenty-first century in two Himalayan glacierized watersheds. Nature Geoscience. 2013;6(9):742-745. doi:10.1038/ngeo1896"},"doi":"10.1038/ngeo1896","quality_controlled":"1","extern":"1","intvolume":" 6","year":"2013","language":[{"iso":"eng"}],"publication_identifier":{"eissn":["1752-0908"],"issn":["1752-0894"]},"page":"742-745","abstract":[{"lang":"eng","text":"Greater Himalayan glaciers are retreating and losing mass at rates comparable to glaciers in other regions of the world1,2,3,4,5. Assessments of future changes and their associated hydrological impacts are scarce, oversimplify glacier dynamics or include a limited number of climate models6,7,8,9. Here, we use results from the latest ensemble of climate models in combination with a high-resolution glacio-hydrological model to assess the hydrological impact of climate change on two climatically contrasting watersheds in the Greater Himalaya, the Baltoro and Langtang watersheds that drain into the Indus and Ganges rivers, respectively. We show that the largest uncertainty in future runoff is a result of variations in projected precipitation between climate models. In both watersheds, strong, but highly variable, increases in future runoff are projected and, despite the different characteristics of the watersheds, their responses are surprisingly similar. In both cases, glaciers will recede but net glacier melt runoff is on a rising limb at least until 2050. In combination with a positive change in precipitation, water availability during this century is not likely to decline. We conclude that river basins that depend on monsoon rains and glacier melt will continue to sustain the increasing water demands expected in these areas10."}],"keyword":["General Earth and Planetary Sciences"]},{"page":"311-321","abstract":[{"lang":"eng","text":"We investigate the sensitivity of a distributed enhanced temperature-index (ETI) melt model, in order to understand which parameters have the largest influence on model outputs and thus need to be accurately known. We use melt and meteorological data from two Alpine glaciers and one glacier in the Andes of Chile. Sensitivity analysis is conducted in a systematic way in terms of parameters and the different conditions (day, night, clear-sky, overcast), melt seasons and glaciers examined. The sensitivity of total melt to changes in individual parameters is calculated using a local method around the optimal value of the parameters. We verify that the parameters are optimal at the distributed scale and assess the model uncertainty induced by uncertainty in the parameters using a Monte Carlo technique. Model sensitivity to parameters is consistent across melt seasons, glaciers, different conditions and the daily statistics examined. The parameters to which the model is most sensitive are the shortwave-radiation factor, the temperature lapse rate for extrapolation of air temperature, the albedo parameters, the temperature threshold and the cloud transmittance factor parameters. A parameter uncertainty of 5% results in a model uncertainty of 5.6% of mean melt on Haut Glacier d’Arolla, Switzerland."}],"oa":1,"extern":"1","quality_controlled":"1","citation":{"mla":"Heynen, Martin, et al. “Parameter Sensitivity of a Distributed Enhanced Temperature-Index Melt Model.” Annals of Glaciology, vol. 54, no. 63, International Glaciological Society, 2013, pp. 311–21, doi:10.3189/2013aog63a537.","ieee":"M. Heynen, F. Pellicciotti, and M. Carenzo, “Parameter sensitivity of a distributed enhanced temperature-index melt model,” Annals of Glaciology, vol. 54, no. 63. International Glaciological Society, pp. 311–321, 2013.","ista":"Heynen M, Pellicciotti F, Carenzo M. 2013. Parameter sensitivity of a distributed enhanced temperature-index melt model. Annals of Glaciology. 54(63), 311–321.","short":"M. Heynen, F. Pellicciotti, M. Carenzo, Annals of Glaciology 54 (2013) 311–321.","chicago":"Heynen, Martin, Francesca Pellicciotti, and Marco Carenzo. “Parameter Sensitivity of a Distributed Enhanced Temperature-Index Melt Model.” Annals of Glaciology. International Glaciological Society, 2013. https://doi.org/10.3189/2013aog63a537.","apa":"Heynen, M., Pellicciotti, F., & Carenzo, M. (2013). Parameter sensitivity of a distributed enhanced temperature-index melt model. Annals of Glaciology. International Glaciological Society. https://doi.org/10.3189/2013aog63a537","ama":"Heynen M, Pellicciotti F, Carenzo M. Parameter sensitivity of a distributed enhanced temperature-index melt model. Annals of Glaciology. 2013;54(63):311-321. doi:10.3189/2013aog63a537"},"doi":"10.3189/2013aog63a537","language":[{"iso":"eng"}],"publication_identifier":{"issn":["0260-3055"],"eissn":["1727-5644"]},"year":"2013","intvolume":" 54","main_file_link":[{"open_access":"1","url":"https://doi.org/10.3189/2013aog63a537"}],"scopus_import":"1","article_type":"original","month":"08","date_published":"2013-08-01T00:00:00Z","date_updated":"2023-02-21T10:43:42Z","publisher":"International Glaciological Society","publication_status":"published","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"Annals of Glaciology","_id":"12641","article_processing_charge":"No","issue":"63","type":"journal_article","date_created":"2023-02-20T08:17:21Z","oa_version":"Published Version","author":[{"last_name":"Heynen","first_name":"Martin","full_name":"Heynen, Martin"},{"last_name":"Pellicciotti","first_name":"Francesca","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70","full_name":"Pellicciotti, Francesca"},{"full_name":"Carenzo, Marco","last_name":"Carenzo","first_name":"Marco"}],"day":"01","status":"public","title":"Parameter sensitivity of a distributed enhanced temperature-index melt model","volume":54},{"intvolume":" 54","year":"2013","language":[{"iso":"eng"}],"publication_identifier":{"issn":["0260-3055"],"eissn":["1727-5644"]},"doi":"10.3189/2013aog63a477","citation":{"mla":"Petersen, Lene, et al. “Suitability of a Constant Air Temperature Lapse Rate over an Alpine Glacier: Testing the Greuell and Böhm Model as an Alternative.” Annals of Glaciology, vol. 54, no. 63, International Glaciological Society, 2013, pp. 120–30, doi:10.3189/2013aog63a477.","ieee":"L. Petersen, F. Pellicciotti, I. Juszak, M. Carenzo, and B. Brock, “Suitability of a constant air temperature lapse rate over an Alpine glacier: Testing the Greuell and Böhm model as an alternative,” Annals of Glaciology, vol. 54, no. 63. International Glaciological Society, pp. 120–130, 2013.","ista":"Petersen L, Pellicciotti F, Juszak I, Carenzo M, Brock B. 2013. Suitability of a constant air temperature lapse rate over an Alpine glacier: Testing the Greuell and Böhm model as an alternative. Annals of Glaciology. 54(63), 120–130.","short":"L. Petersen, F. Pellicciotti, I. Juszak, M. Carenzo, B. Brock, Annals of Glaciology 54 (2013) 120–130.","chicago":"Petersen, Lene, Francesca Pellicciotti, Inge Juszak, Marco Carenzo, and Ben Brock. “Suitability of a Constant Air Temperature Lapse Rate over an Alpine Glacier: Testing the Greuell and Böhm Model as an Alternative.” Annals of Glaciology. International Glaciological Society, 2013. https://doi.org/10.3189/2013aog63a477.","apa":"Petersen, L., Pellicciotti, F., Juszak, I., Carenzo, M., & Brock, B. (2013). Suitability of a constant air temperature lapse rate over an Alpine glacier: Testing the Greuell and Böhm model as an alternative. Annals of Glaciology. International Glaciological Society. https://doi.org/10.3189/2013aog63a477","ama":"Petersen L, Pellicciotti F, Juszak I, Carenzo M, Brock B. Suitability of a constant air temperature lapse rate over an Alpine glacier: Testing the Greuell and Böhm model as an alternative. Annals of Glaciology. 2013;54(63):120-130. doi:10.3189/2013aog63a477"},"quality_controlled":"1","extern":"1","oa":1,"abstract":[{"lang":"eng","text":"Near-surface air temperature, typically measured at a height of 2 m, is the most important control on the energy exchange and the melt rate at a snow or ice surface. It is distributed in a simplistic manner in most glacier melt models by using constant linear lapse rates, which poorly represent the actual spatial and temporal variability of air temperature. In this paper, we test a simple thermodynamic model proposed by Greuell and Böhm in 1998 as an alternative, using a new dataset of air temperature measurements from along the flowline of Haut Glacier d’Arolla, Switzerland. The unmodified model performs little better than assuming a constant linear lapse rate. When modified to allow the ratio of the boundary layer height to the bulk heat transfer coefficient to vary along the flowline, the model matches measured air temperatures better, and a further reduction of the root-mean-square error is obtained, although there is still considerable scope for improvement. The modified model is shown to perform best under conditions favourable to the development of katabatic winds – few clouds, positive ambient air temperature, limited influence of synoptic or valley winds and a long fetch – but its performance is poor under cloudy conditions."}],"keyword":["Earth-Surface Processes"],"page":"120-130","title":"Suitability of a constant air temperature lapse rate over an Alpine glacier: Testing the Greuell and Böhm model as an alternative","volume":54,"status":"public","day":"01","author":[{"last_name":"Petersen","first_name":"Lene","full_name":"Petersen, Lene"},{"first_name":"Francesca","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70","last_name":"Pellicciotti","full_name":"Pellicciotti, Francesca"},{"full_name":"Juszak, Inge","first_name":"Inge","last_name":"Juszak"},{"full_name":"Carenzo, Marco","last_name":"Carenzo","first_name":"Marco"},{"first_name":"Ben","last_name":"Brock","full_name":"Brock, Ben"}],"oa_version":"Published Version","date_created":"2023-02-20T08:17:29Z","type":"journal_article","_id":"12642","article_processing_charge":"No","issue":"63","publication":"Annals of Glaciology","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","publisher":"International Glaciological Society","date_updated":"2023-02-21T10:18:24Z","date_published":"2013-08-01T00:00:00Z","month":"08","article_type":"original","scopus_import":"1","main_file_link":[{"url":"https://doi.org/10.3189/2013aog63a477","open_access":"1"}]},{"keyword":["Space and Planetary Science","Earth and Planetary Sciences (miscellaneous)","Atmospheric Science","Geophysics"],"abstract":[{"text":"Parameterizations of incoming longwave radiation are increasingly receiving attention for both low and high elevation glacierized sites. In this paper, we test 13 clear-sky parameterizations combined with seven cloud corrections for all-sky atmospheric emissivity at one location on Haut Glacier d'Arolla. We also analyze the four seasons separately and conduct a cross-validation to test the parameters’ robustness. The best parameterization is the one by Dilley and O'Brien, B for clear-sky conditions combined with Unsworth and Monteith cloud correction. This model is also the most robust when tested in cross-validation. When validated at different sites in the southern Alps of Switzerland and north-western Italian Alps, all parameterizations show a substantial decrease in performance, except for one site, thus suggesting that it is important to recalibrate parameterizations of incoming longwave radiation for different locations. We argue that this is due to differences in the structure of the atmosphere at the sites. We also quantify the effect that the incoming longwave radiation parameterizations have on energy-balance melt modeling, and show that recalibration of model parameters is needed. Using parameters from other sites leads to a significant underestimation of melt and to an error that is larger than that associated with using different parameterizations. Once recalibrated, however, the parameters of most models seem to be stable over seasons and years at the location on Haut Glacier d'Arolla.","lang":"eng"}],"oa":1,"page":"3066-3084","publication_identifier":{"issn":["2169-897X"]},"language":[{"iso":"eng"}],"year":"2013","intvolume":" 118","extern":"1","quality_controlled":"1","doi":"10.1002/jgrd.50277","citation":{"ama":"Juszak I, Pellicciotti F. A comparison of parameterizations of incoming longwave radiation over melting glaciers: Model robustness and seasonal variability. Journal of Geophysical Research: Atmospheres. 2013;118(8):3066-3084. doi:10.1002/jgrd.50277","ista":"Juszak I, Pellicciotti F. 2013. A comparison of parameterizations of incoming longwave radiation over melting glaciers: Model robustness and seasonal variability. Journal of Geophysical Research: Atmospheres. 118(8), 3066–3084.","ieee":"I. Juszak and F. Pellicciotti, “A comparison of parameterizations of incoming longwave radiation over melting glaciers: Model robustness and seasonal variability,” Journal of Geophysical Research: Atmospheres, vol. 118, no. 8. American Geophysical Union, pp. 3066–3084, 2013.","mla":"Juszak, I., and Francesca Pellicciotti. “A Comparison of Parameterizations of Incoming Longwave Radiation over Melting Glaciers: Model Robustness and Seasonal Variability.” Journal of Geophysical Research: Atmospheres, vol. 118, no. 8, American Geophysical Union, 2013, pp. 3066–84, doi:10.1002/jgrd.50277.","apa":"Juszak, I., & Pellicciotti, F. (2013). A comparison of parameterizations of incoming longwave radiation over melting glaciers: Model robustness and seasonal variability. Journal of Geophysical Research: Atmospheres. American Geophysical Union. https://doi.org/10.1002/jgrd.50277","short":"I. Juszak, F. Pellicciotti, Journal of Geophysical Research: Atmospheres 118 (2013) 3066–3084.","chicago":"Juszak, I., and Francesca Pellicciotti. “A Comparison of Parameterizations of Incoming Longwave Radiation over Melting Glaciers: Model Robustness and Seasonal Variability.” Journal of Geophysical Research: Atmospheres. American Geophysical Union, 2013. https://doi.org/10.1002/jgrd.50277."},"article_type":"original","date_published":"2013-04-27T00:00:00Z","month":"04","date_updated":"2023-02-21T10:10:46Z","publisher":"American Geophysical Union","publication_status":"published","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","main_file_link":[{"url":"https://doi.org/10.1002/jgrd.50277","open_access":"1"}],"scopus_import":"1","day":"27","status":"public","title":"A comparison of parameterizations of incoming longwave radiation over melting glaciers: Model robustness and seasonal variability","volume":118,"publication":"Journal of Geophysical Research: Atmospheres","_id":"12643","issue":"8","article_processing_charge":"No","type":"journal_article","date_created":"2023-02-20T08:17:34Z","oa_version":"Published Version","author":[{"full_name":"Juszak, I.","last_name":"Juszak","first_name":"I."},{"last_name":"Pellicciotti","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70","first_name":"Francesca","full_name":"Pellicciotti, Francesca"}]},{"day":"01","year":"2013","title":"Optogenetic control of fly optomotor responses","volume":33,"status":"public","intvolume":" 33","doi":"10.1523/JNEUROSCI.0340-13.2013","citation":{"short":"V. Haikala, M.A. Jösch, A. Borst, A. Mauss, Journal of Neuroscience 33 (2013) 13927–13934.","chicago":"Haikala, Väinö, Maximilian A Jösch, Alexander Borst, and Alex Mauss. “Optogenetic Control of Fly Optomotor Responses.” Journal of Neuroscience. Society for Neuroscience, 2013. https://doi.org/10.1523/JNEUROSCI.0340-13.2013.","apa":"Haikala, V., Jösch, M. A., Borst, A., & Mauss, A. (2013). Optogenetic control of fly optomotor responses. Journal of Neuroscience. Society for Neuroscience. https://doi.org/10.1523/JNEUROSCI.0340-13.2013","mla":"Haikala, Väinö, et al. “Optogenetic Control of Fly Optomotor Responses.” Journal of Neuroscience, vol. 33, no. 34, Society for Neuroscience, 2013, pp. 13927–34, doi:10.1523/JNEUROSCI.0340-13.2013.","ieee":"V. Haikala, M. A. Jösch, A. Borst, and A. Mauss, “Optogenetic control of fly optomotor responses,” Journal of Neuroscience, vol. 33, no. 34. Society for Neuroscience, pp. 13927–13934, 2013.","ista":"Haikala V, Jösch MA, Borst A, Mauss A. 2013. Optogenetic control of fly optomotor responses. Journal of Neuroscience. 33(34), 13927–13934.","ama":"Haikala V, Jösch MA, Borst A, Mauss A. Optogenetic control of fly optomotor responses. Journal of Neuroscience. 2013;33(34):13927-13934. doi:10.1523/JNEUROSCI.0340-13.2013"},"quality_controlled":0,"date_created":"2018-12-11T11:51:16Z","issue":"34","_id":"1304","type":"journal_article","extern":1,"publication":"Journal of Neuroscience","author":[{"first_name":"Väinö","last_name":"Haikala","full_name":"Haikala, Väinö"},{"first_name":"Maximilian A","id":"2BD278E6-F248-11E8-B48F-1D18A9856A87","last_name":"Jösch","full_name":"Maximilian Jösch","orcid":"0000-0002-3937-1330"},{"full_name":"Borst, Alexander","last_name":"Borst","first_name":"Alexander"},{"last_name":"Mauss","first_name":"Alex","full_name":"Mauss, Alex S"}],"acknowledgement":"This work was supported by the Max Planck Society. ","abstract":[{"text":"When confronted with a large-field stimulus rotating around the vertical body axis, flies display a following behavior called "optomotor response." As neural control elements, the large tangential horizontal system (HS) cells of the lobula plate have been prime candidates for long. Here, we applied optogenetic stimulation of HS cells to evaluate their behavioral role in Drosophila. To minimize interference of the optical activation of channelrhodopsin-2 with the visual perception of the flies, we used a bistable variant called ChR2-C128S. By applying pulses of blue and yellow light, we first demonstrate electrophysiologically that lobula plate tangential cells can be activated and deactivated repeatedly with no evident change in depolarization strength over trials. We next show that selective optogenetic activation of HS cells elicits robust yaw head movements and yaw turning responses in fixed and tethered flying flies, respectively.","lang":"eng"}],"month":"01","date_published":"2013-01-01T00:00:00Z","publication_status":"published","publisher":"Society for Neuroscience","date_updated":"2021-01-12T06:49:45Z","publist_id":"5967","page":"13927 - 13934"},{"year":"2013","day":"16","intvolume":" 33","status":"public","volume":33,"title":"Functional specialization of parallel motion detection circuits in the fly","issue":"3","_id":"1305","type":"journal_article","extern":1,"publication":"Journal of Neuroscience","citation":{"ista":"Jösch MA, Weber F, Eichner H, Borst A. 2013. Functional specialization of parallel motion detection circuits in the fly. Journal of Neuroscience. 33(3), 902–905.","ieee":"M. A. Jösch, F. Weber, H. Eichner, and A. Borst, “Functional specialization of parallel motion detection circuits in the fly,” Journal of Neuroscience, vol. 33, no. 3. Society for Neuroscience, pp. 902–905, 2013.","mla":"Jösch, Maximilian A., et al. “Functional Specialization of Parallel Motion Detection Circuits in the Fly.” Journal of Neuroscience, vol. 33, no. 3, Society for Neuroscience, 2013, pp. 902–05, doi:10.1523/JNEUROSCI.3374-12.2013.","apa":"Jösch, M. A., Weber, F., Eichner, H., & Borst, A. (2013). Functional specialization of parallel motion detection circuits in the fly. Journal of Neuroscience. Society for Neuroscience. https://doi.org/10.1523/JNEUROSCI.3374-12.2013","short":"M.A. Jösch, F. Weber, H. Eichner, A. Borst, Journal of Neuroscience 33 (2013) 902–905.","chicago":"Jösch, Maximilian A, Franz Weber, Hubert Eichner, and Alexander Borst. “Functional Specialization of Parallel Motion Detection Circuits in the Fly.” Journal of Neuroscience. Society for Neuroscience, 2013. https://doi.org/10.1523/JNEUROSCI.3374-12.2013.","ama":"Jösch MA, Weber F, Eichner H, Borst A. Functional specialization of parallel motion detection circuits in the fly. Journal of Neuroscience. 2013;33(3):902-905. doi:10.1523/JNEUROSCI.3374-12.2013"},"doi":"10.1523/JNEUROSCI.3374-12.2013","date_created":"2018-12-11T11:51:16Z","quality_controlled":0,"acknowledgement":"This work was supported by the Max-Planck-Society and the SFB 870 of the Deutsche Forschungsgemeinschaft.","author":[{"orcid":"0000-0002-3937-1330","full_name":"Maximilian Jösch","last_name":"Jösch","id":"2BD278E6-F248-11E8-B48F-1D18A9856A87","first_name":"Maximilian A"},{"full_name":"Weber, Franz","last_name":"Weber","first_name":"Franz"},{"full_name":"Eichner, Hubert","last_name":"Eichner","first_name":"Hubert"},{"last_name":"Borst","first_name":"Alexander","full_name":"Borst, Alexander"}],"month":"01","date_published":"2013-01-16T00:00:00Z","abstract":[{"lang":"eng","text":"In the fly Drosophila melanogaster, photoreceptor input to motion vision is split into two parallel pathways as represented by first-order interneurons L1 and L2 (Rister et al., 2007; Joesch et al., 2010). However, how these pathways are functionally specialized remains controversial. One study (Eichner et al., 2011) proposed that the L1-pathway evaluates only sequences of brightness increments (ON-ON), while the L2-pathway processes exclusively brightness decrements (OFF-OFF). Another study (Clark et al., 2011) proposed that each of the two pathways evaluates both ON-ON and OFF-OFF sequences. To decide between these alternatives, we recorded from motionsensitive neurons in flies in which the output from either L1 or L2 was genetically blocked. We found that blocking L1 abolishes ON-ON responses but leaves OFF-OFF responses intact. The opposite was true, when the output from L2 was blocked. We conclude that the L1 and L2 pathways are functionally specialized to detect ON-ON and OFF-OFF sequences, respectively."}],"publisher":"Society for Neuroscience","publist_id":"5968","date_updated":"2021-01-12T06:49:45Z","publication_status":"published","page":"902 - 905"},{"page":"2004 - 2047","publisher":"Taylor & Francis","date_updated":"2021-01-12T06:49:46Z","publist_id":"5962","publication_status":"published","month":"11","date_published":"2013-11-01T00:00:00Z","abstract":[{"lang":"eng","text":"We prove uniqueness of solutions of the DLSS equation in a class of sufficiently regular functions. The global weak solutions of the DLSS equation constructed by Jüngel and Matthes belong to this class of uniqueness. We also show uniqueness of solutions for the quantum drift-diffusion equation, which contains additional drift and second-order diffusion terms. The results hold in case of periodic or Dirichlet-Neumann boundary conditions. Our proof is based on a monotonicity property of the DLSS operator and sophisticated approximation arguments; we derive a PDE satisfied by the pointwise square root of the solution, which enables us to exploit the monotonicity property of the operator."}],"author":[{"last_name":"Fischer","first_name":"Julian L","id":"2C12A0B0-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-0479-558X","full_name":"Julian Fischer"}],"type":"journal_article","_id":"1307","issue":"11","publication":"Communications in Partial Differential Equations","extern":1,"doi":"10.1080/03605302.2013.823548","citation":{"short":"J.L. Fischer, Communications in Partial Differential Equations 38 (2013) 2004–2047.","chicago":"Fischer, Julian L. “Uniqueness of Solutions of the Derrida-Lebowitz-Speer-Spohn Equation and Quantum Drift Diffusion Models.” Communications in Partial Differential Equations. Taylor & Francis, 2013. https://doi.org/10.1080/03605302.2013.823548.","apa":"Fischer, J. L. (2013). Uniqueness of solutions of the Derrida-Lebowitz-Speer-Spohn equation and quantum drift diffusion models. Communications in Partial Differential Equations. Taylor & Francis. https://doi.org/10.1080/03605302.2013.823548","mla":"Fischer, Julian L. “Uniqueness of Solutions of the Derrida-Lebowitz-Speer-Spohn Equation and Quantum Drift Diffusion Models.” Communications in Partial Differential Equations, vol. 38, no. 11, Taylor & Francis, 2013, pp. 2004–47, doi:10.1080/03605302.2013.823548.","ista":"Fischer JL. 2013. Uniqueness of solutions of the Derrida-Lebowitz-Speer-Spohn equation and quantum drift diffusion models. Communications in Partial Differential Equations. 38(11), 2004–2047.","ieee":"J. L. Fischer, “Uniqueness of solutions of the Derrida-Lebowitz-Speer-Spohn equation and quantum drift diffusion models,” Communications in Partial Differential Equations, vol. 38, no. 11. Taylor & Francis, pp. 2004–2047, 2013.","ama":"Fischer JL. Uniqueness of solutions of the Derrida-Lebowitz-Speer-Spohn equation and quantum drift diffusion models. Communications in Partial Differential Equations. 2013;38(11):2004-2047. doi:10.1080/03605302.2013.823548"},"quality_controlled":0,"date_created":"2018-12-11T11:51:17Z","status":"public","intvolume":" 38","title":"Uniqueness of solutions of the Derrida-Lebowitz-Speer-Spohn equation and quantum drift diffusion models","volume":38,"day":"01","year":"2013"},{"year":"2013","day":"01","volume":45,"title":"Advection-driven support shrinking in a chemotaxis model with degenerate mobility","intvolume":" 45","status":"public","date_created":"2018-12-11T11:51:17Z","quality_controlled":0,"citation":{"chicago":"Fischer, Julian L. “Advection-Driven Support Shrinking in a Chemotaxis Model with Degenerate Mobility.” SIAM Journal on Mathematical Analysis. Society for Industrial and Applied Mathematics , 2013. https://doi.org/10.1137/120874291.","short":"J.L. Fischer, SIAM Journal on Mathematical Analysis 45 (2013) 1585–1615.","apa":"Fischer, J. L. (2013). Advection-driven support shrinking in a chemotaxis model with degenerate mobility. SIAM Journal on Mathematical Analysis. Society for Industrial and Applied Mathematics . https://doi.org/10.1137/120874291","mla":"Fischer, Julian L. “Advection-Driven Support Shrinking in a Chemotaxis Model with Degenerate Mobility.” SIAM Journal on Mathematical Analysis, vol. 45, no. 3, Society for Industrial and Applied Mathematics , 2013, pp. 1585–615, doi:10.1137/120874291.","ista":"Fischer JL. 2013. Advection-driven support shrinking in a chemotaxis model with degenerate mobility. SIAM Journal on Mathematical Analysis. 45(3), 1585–1615.","ieee":"J. L. Fischer, “Advection-driven support shrinking in a chemotaxis model with degenerate mobility,” SIAM Journal on Mathematical Analysis, vol. 45, no. 3. Society for Industrial and Applied Mathematics , pp. 1585–1615, 2013.","ama":"Fischer JL. Advection-driven support shrinking in a chemotaxis model with degenerate mobility. SIAM Journal on Mathematical Analysis. 2013;45(3):1585-1615. doi:10.1137/120874291"},"doi":"10.1137/120874291","publication":"SIAM Journal on Mathematical Analysis","extern":1,"issue":"3","_id":"1308","type":"journal_article","author":[{"orcid":"0000-0002-0479-558X","full_name":"Julian Fischer","id":"2C12A0B0-F248-11E8-B48F-1D18A9856A87","first_name":"Julian L","last_name":"Fischer"}],"abstract":[{"text":"We derive sufficient conditions for advection-driven backward motion of the free boundary in a chemotaxis model with degenerate mobility. In this model, a porous-medium-type diffusive term and an advection term are in competition. The former induces forward motion, the latter may induce backward motion of the free boundary depending on the direction of advection. We deduce conditions on the growth of the initial data at the free boundary which ensure that at least initially the advection term is dominant. This implies local backward motion of the free boundary provided the advection is (locally) directed appropriately. Our result is based on a new class of moving test functions and Stampacchia's lemma. As a by-product of our estimates, we obtain quantitative bounds on the spreading of the support of solutions for the chemotaxis model and provide a proof for the finite speed of the support propagation property of solutions.","lang":"eng"}],"month":"01","date_published":"2013-01-01T00:00:00Z","publication_status":"published","publist_id":"5963","date_updated":"2021-01-12T06:49:46Z","publisher":"Society for Industrial and Applied Mathematics ","page":"1585 - 1615"},{"page":"3127 - 3149","publisher":"Academic Press","publist_id":"5961","date_updated":"2021-01-12T06:49:47Z","publication_status":"published","date_published":"2013-11-15T00:00:00Z","month":"11","abstract":[{"text":"We derive lower bounds on asymptotic support propagation rates for strong solutions of the Cauchy problem for the thin-film equation. The bounds coincide up to a constant factor with the previously known upper bounds and thus are sharp. Our results hold in case of at most three spatial dimensions and n∈. (1, 2.92). The result is established using weighted backward entropy inequalities with singular weight functions to yield a differential inequality; combined with some entropy production estimates, the optimal rate of propagation is obtained. To the best of our knowledge, these are the first lower bounds on asymptotic support propagation rates for higher-order nonnegativity-preserving parabolic equations.","lang":"eng"}],"author":[{"orcid":"0000-0002-0479-558X","full_name":"Julian Fischer","id":"2C12A0B0-F248-11E8-B48F-1D18A9856A87","first_name":"Julian L","last_name":"Fischer"}],"issue":"10","_id":"1310","type":"journal_article","publication":"Journal of Differential Equations","extern":1,"citation":{"ama":"Fischer JL. Optimal lower bounds on asymptotic support propagation rates for the thin-film equation. Journal of Differential Equations. 2013;255(10):3127-3149. doi:10.1016/j.jde.2013.07.028","apa":"Fischer, J. L. (2013). Optimal lower bounds on asymptotic support propagation rates for the thin-film equation. Journal of Differential Equations. Academic Press. https://doi.org/10.1016/j.jde.2013.07.028","short":"J.L. Fischer, Journal of Differential Equations 255 (2013) 3127–3149.","chicago":"Fischer, Julian L. “Optimal Lower Bounds on Asymptotic Support Propagation Rates for the Thin-Film Equation.” Journal of Differential Equations. Academic Press, 2013. https://doi.org/10.1016/j.jde.2013.07.028.","ieee":"J. L. Fischer, “Optimal lower bounds on asymptotic support propagation rates for the thin-film equation,” Journal of Differential Equations, vol. 255, no. 10. Academic Press, pp. 3127–3149, 2013.","ista":"Fischer JL. 2013. Optimal lower bounds on asymptotic support propagation rates for the thin-film equation. Journal of Differential Equations. 255(10), 3127–3149.","mla":"Fischer, Julian L. “Optimal Lower Bounds on Asymptotic Support Propagation Rates for the Thin-Film Equation.” Journal of Differential Equations, vol. 255, no. 10, Academic Press, 2013, pp. 3127–49, doi:10.1016/j.jde.2013.07.028."},"doi":"10.1016/j.jde.2013.07.028","date_created":"2018-12-11T11:51:18Z","quality_controlled":0,"status":"public","intvolume":" 255","volume":255,"title":"Optimal lower bounds on asymptotic support propagation rates for the thin-film equation","day":"15","year":"2013"},{"user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","publication_status":"published","publisher":"Springer Nature","date_updated":"2022-08-25T14:52:39Z","month":"12","date_published":"2013-12-12T00:00:00Z","author":[{"full_name":"Petricevic, Branka","first_name":"Branka","last_name":"Petricevic"},{"last_name":"Laengle","first_name":"Johannes","full_name":"Laengle, Johannes"},{"first_name":"Josef","last_name":"Singer","full_name":"Singer, Josef"},{"last_name":"Sachet","first_name":"Monika","full_name":"Sachet, Monika"},{"last_name":"Fazekas","id":"36432834-F248-11E8-B48F-1D18A9856A87","first_name":"Judit","full_name":"Fazekas, Judit","orcid":"0000-0002-8777-3502"},{"full_name":"Steger, Guenther","last_name":"Steger","first_name":"Guenther"},{"full_name":"Bartsch, Rupert","last_name":"Bartsch","first_name":"Rupert"},{"first_name":"Erika","last_name":"Jensen-Jarolim","full_name":"Jensen-Jarolim, Erika"},{"last_name":"Bergmann","first_name":"Michael","full_name":"Bergmann, Michael"}],"oa_version":"None","date_created":"2020-08-10T11:54:34Z","_id":"8245","article_processing_charge":"No","type":"journal_article","file_date_updated":"2020-08-10T13:45:19Z","publication":"Journal of Translational Medicine","tmp":{"image":"/images/cc_by.png","short":"CC BY (3.0)","name":"Creative Commons Attribution 3.0 Unported (CC BY 3.0)","legal_code_url":"https://creativecommons.org/licenses/by/3.0/legalcode"},"title":"Trastuzumab mediates antibody-dependent cell-mediated cytotoxicity and phagocytosis to the same extent in both adjuvant and metastatic HER2/neu breast cancer patients","volume":11,"article_number":"307","status":"public","day":"12","license":"https://creativecommons.org/licenses/by/3.0/","external_id":{"pmid":["24330813"]},"ddc":["570"],"oa":1,"abstract":[{"lang":"eng","text":"Background: Monoclonal antibodies (mAb), such as trastuzumab are a valuable addition to breast cancer therapy.\r\nData obtained from neoadjuvant settings revealed that antibody-dependent cell-mediated cytotoxicity (ADCC) is a\r\nmajor mechanism of action for the mAb trastuzumab. Conflicting results still call into question whether disease\r\nprogression, prolonged treatment or concomitant chemotherapy influences ADCC and related immunological\r\nphenomena.\r\nMethods: We analyzed the activity of ADCC and antibody-dependent cell-mediated phagocytosis (ADCP) of\r\nperipheral blood mononuclear cells (PBMCs) from human epidermal growth factor receptor 2 (HER2/neu) positive\r\nbreast cancer patients receiving trastuzumab therapy either in an adjuvant (n = 13) or metastatic (n = 15) setting as\r\nwell as from trastuzumab treatment-naive (t-naive) HER2/neu negative patients (n = 15). PBMCs from healthy volunteers\r\n(n = 24) were used as controls. ADCC and ADCP activity was correlated with the expression of antibody binding\r\nFc-gamma receptor (FcγR)I (CD64), FcγRII (CD32) and FcγRIII (CD16) on CD14+ (monocytes) and CD56+ (NK) cells, as well as the expression of CD107a+ (LAMP-1) on CD56+ cells and the total amount of CD4+CD25+FOXP3+ (Treg) cells. In metastatic patients, markers were correlated with progression-free survival (PFS).\r\nResults: ADCC activity was significantly down regulated in metastatic, adjuvant and t-naive patient cohorts as compared to healthy controls. Reduced ADCC activity was inversely correlated with the expression of CD107a on CD56+\r\ncells in adjuvant patients. ADCC and ADCP activity of the patient cohorts were similar, regardless of treatment duration\r\nor additional chemotherapy. PFS in metastatic patients inversely correlated with the number of peripheral Treg cells.\r\nConclusion: The reduction of ADCC in patients as compared to healthy controls calls for adjuvant strategies, such as\r\nimmune-enhancing agents, to improve the activity of trastuzumab. However, efficacy of trastuzumab-specific ADCC\r\nand ADCP appears not to be affected by treatment duration, disease progression or concomitant chemotherapy. This\r\nfinding supports the application of trastuzumab at any stage of the disease."}],"file":[{"file_name":"2013_JoTM_Petricevic.pdf","relation":"main_file","content_type":"application/pdf","success":1,"date_created":"2020-08-10T13:45:19Z","access_level":"open_access","file_id":"8247","date_updated":"2020-08-10T13:45:19Z","creator":"dernst","file_size":777311}],"citation":{"ama":"Petricevic B, Laengle J, Singer J, et al. Trastuzumab mediates antibody-dependent cell-mediated cytotoxicity and phagocytosis to the same extent in both adjuvant and metastatic HER2/neu breast cancer patients. Journal of Translational Medicine. 2013;11. doi:10.1186/1479-5876-11-307","apa":"Petricevic, B., Laengle, J., Singer, J., Sachet, M., Singer, J., Steger, G., … Bergmann, M. (2013). Trastuzumab mediates antibody-dependent cell-mediated cytotoxicity and phagocytosis to the same extent in both adjuvant and metastatic HER2/neu breast cancer patients. Journal of Translational Medicine. Springer Nature. https://doi.org/10.1186/1479-5876-11-307","short":"B. Petricevic, J. Laengle, J. Singer, M. Sachet, J. Singer, G. Steger, R. Bartsch, E. Jensen-Jarolim, M. Bergmann, Journal of Translational Medicine 11 (2013).","chicago":"Petricevic, Branka, Johannes Laengle, Josef Singer, Monika Sachet, Judit Singer, Guenther Steger, Rupert Bartsch, Erika Jensen-Jarolim, and Michael Bergmann. “Trastuzumab Mediates Antibody-Dependent Cell-Mediated Cytotoxicity and Phagocytosis to the Same Extent in Both Adjuvant and Metastatic HER2/Neu Breast Cancer Patients.” Journal of Translational Medicine. Springer Nature, 2013. https://doi.org/10.1186/1479-5876-11-307.","ieee":"B. Petricevic et al., “Trastuzumab mediates antibody-dependent cell-mediated cytotoxicity and phagocytosis to the same extent in both adjuvant and metastatic HER2/neu breast cancer patients,” Journal of Translational Medicine, vol. 11. Springer Nature, 2013.","ista":"Petricevic B, Laengle J, Singer J, Sachet M, Singer J, Steger G, Bartsch R, Jensen-Jarolim E, Bergmann M. 2013. Trastuzumab mediates antibody-dependent cell-mediated cytotoxicity and phagocytosis to the same extent in both adjuvant and metastatic HER2/neu breast cancer patients. Journal of Translational Medicine. 11, 307.","mla":"Petricevic, Branka, et al. “Trastuzumab Mediates Antibody-Dependent Cell-Mediated Cytotoxicity and Phagocytosis to the Same Extent in Both Adjuvant and Metastatic HER2/Neu Breast Cancer Patients.” Journal of Translational Medicine, vol. 11, 307, Springer Nature, 2013, doi:10.1186/1479-5876-11-307."},"doi":"10.1186/1479-5876-11-307","quality_controlled":"1","extern":"1","has_accepted_license":"1","pmid":1,"intvolume":" 11","year":"2013","language":[{"iso":"eng"}],"publication_identifier":{"issn":["1479-5876"]}}]