[{"_id":"995","oa":1,"publication":"Physical Review B - Condensed Matter and Materials Physics","title":"Diagrammatic approach to orbital quantum impurities interacting with a many-particle environment","abstract":[{"lang":"eng","text":"Recently it was shown that an impurity exchanging orbital angular momentum with a surrounding bath can be described in terms of the angulon quasiparticle [Phys. Rev. Lett. 118, 095301 (2017)]. The angulon consists of a quantum rotor dressed by a many-particle field of boson excitations, and can be formed out of, for example, a molecule or a nonspherical atom in superfluid helium, or out of an electron coupled to lattice phonons or a Bose condensate. Here we develop an approach to the angulon based on the path-integral formalism, which sets the ground for a systematic, perturbative treatment of the angulon problem. The resulting perturbation series can be interpreted in terms of Feynman diagrams, from which, in turn, one can derive a set of diagrammatic rules. These rules extend the machinery of the graphical theory of angular momentum - well known from theoretical atomic spectroscopy - to the case where an environment with an infinite number of degrees of freedom is present. In particular, we show that each diagram can be interpreted as a 'skeleton', which enforces angular momentum conservation, dressed by an additional many-body contribution. This connection between the angulon theory and the graphical theory of angular momentum is particularly important as it allows to systematically and substantially simplify the analytical representation of each diagram. In order to exemplify the technique, we calculate the 1- and 2-loop contributions to the angulon self-energy, the spectral function, and the quasiparticle weight. The diagrammatic theory we develop paves the way to investigate next-to-leading order quantities in a more compact way compared to the variational approaches."}],"publication_status":"published","project":[{"name":"Quantum rotations in the presence of a many-body environment","grant_number":"P29902","_id":"26031614-B435-11E9-9278-68D0E5697425","call_identifier":"FWF"}],"author":[{"first_name":"Giacomo","last_name":"Bighin","id":"4CA96FD4-F248-11E8-B48F-1D18A9856A87","full_name":"Bighin, Giacomo","orcid":"0000-0001-8823-9777"},{"orcid":"0000-0002-6990-7802","full_name":"Lemeshko, Mikhail","id":"37CB05FA-F248-11E8-B48F-1D18A9856A87","last_name":"Lemeshko","first_name":"Mikhail"}],"quality_controlled":"1","main_file_link":[{"url":"https://arxiv.org/abs/1704.02616","open_access":"1"}],"citation":{"ama":"Bighin G, Lemeshko M. Diagrammatic approach to orbital quantum impurities interacting with a many-particle environment. <i>Physical Review B - Condensed Matter and Materials Physics</i>. 2017;96(8). doi:<a href=\"https://doi.org/10.1103/PhysRevB.96.085410\">10.1103/PhysRevB.96.085410</a>","ieee":"G. Bighin and M. Lemeshko, “Diagrammatic approach to orbital quantum impurities interacting with a many-particle environment,” <i>Physical Review B - Condensed Matter and Materials Physics</i>, vol. 96, no. 8. American Physical Society, 2017.","chicago":"Bighin, Giacomo, and Mikhail Lemeshko. “Diagrammatic Approach to Orbital Quantum Impurities Interacting with a Many-Particle Environment.” <i>Physical Review B - Condensed Matter and Materials Physics</i>. American Physical Society, 2017. <a href=\"https://doi.org/10.1103/PhysRevB.96.085410\">https://doi.org/10.1103/PhysRevB.96.085410</a>.","short":"G. Bighin, M. Lemeshko, Physical Review B - Condensed Matter and Materials Physics 96 (2017).","ista":"Bighin G, Lemeshko M. 2017. Diagrammatic approach to orbital quantum impurities interacting with a many-particle environment. Physical Review B - Condensed Matter and Materials Physics. 96(8), 085410.","apa":"Bighin, G., &#38; Lemeshko, M. (2017). Diagrammatic approach to orbital quantum impurities interacting with a many-particle environment. <i>Physical Review B - Condensed Matter and Materials Physics</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevB.96.085410\">https://doi.org/10.1103/PhysRevB.96.085410</a>","mla":"Bighin, Giacomo, and Mikhail Lemeshko. “Diagrammatic Approach to Orbital Quantum Impurities Interacting with a Many-Particle Environment.” <i>Physical Review B - Condensed Matter and Materials Physics</i>, vol. 96, no. 8, 085410, American Physical Society, 2017, doi:<a href=\"https://doi.org/10.1103/PhysRevB.96.085410\">10.1103/PhysRevB.96.085410</a>."},"year":"2017","isi":1,"publist_id":"6404","intvolume":"        96","article_number":"085410","status":"public","month":"08","date_created":"2018-12-11T11:49:36Z","issue":"8","volume":96,"publisher":"American Physical Society","department":[{"_id":"MiLe"}],"doi":"10.1103/PhysRevB.96.085410","language":[{"iso":"eng"}],"article_processing_charge":"No","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","day":"07","oa_version":"Submitted Version","type":"journal_article","date_updated":"2023-09-22T09:53:17Z","scopus_import":"1","publication_identifier":{"issn":["24699950"]},"external_id":{"isi":["000407017100009"]},"date_published":"2017-08-07T00:00:00Z"},{"external_id":{"isi":["000405089400047"]},"date_published":"2017-06-01T00:00:00Z","scopus_import":"1","publication_identifier":{"issn":["00219606"]},"article_processing_charge":"No","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","day":"01","oa_version":"Submitted Version","date_updated":"2024-02-28T13:02:26Z","type":"journal_article","department":[{"_id":"MiLe"}],"language":[{"iso":"eng"}],"doi":"10.1063/1.4983703","volume":147,"issue":"1","publisher":"AIP Publishing","isi":1,"publist_id":"6403","intvolume":"       147","article_number":"013946","status":"public","month":"06","date_created":"2018-12-11T11:49:36Z","author":[{"full_name":"Shepperson, Benjamin","first_name":"Benjamin","last_name":"Shepperson"},{"full_name":"Chatterley, Adam","first_name":"Adam","last_name":"Chatterley"},{"last_name":"Søndergaard","first_name":"Anders","full_name":"Søndergaard, Anders"},{"last_name":"Christiansen","first_name":"Lars","full_name":"Christiansen, Lars"},{"id":"37CB05FA-F248-11E8-B48F-1D18A9856A87","full_name":"Lemeshko, Mikhail","orcid":"0000-0002-6990-7802","last_name":"Lemeshko","first_name":"Mikhail"},{"last_name":"Stapelfeldt","first_name":"Henrik","full_name":"Stapelfeldt, Henrik"}],"quality_controlled":"1","citation":{"mla":"Shepperson, Benjamin, et al. “Strongly Aligned Molecules inside Helium Droplets in the Near-Adiabatic Regime.” <i>The Journal of Chemical Physics</i>, vol. 147, no. 1, 013946, AIP Publishing, 2017, doi:<a href=\"https://doi.org/10.1063/1.4983703\">10.1063/1.4983703</a>.","apa":"Shepperson, B., Chatterley, A., Søndergaard, A., Christiansen, L., Lemeshko, M., &#38; Stapelfeldt, H. (2017). Strongly aligned molecules inside helium droplets in the near-adiabatic regime. <i>The Journal of Chemical Physics</i>. AIP Publishing. <a href=\"https://doi.org/10.1063/1.4983703\">https://doi.org/10.1063/1.4983703</a>","chicago":"Shepperson, Benjamin, Adam Chatterley, Anders Søndergaard, Lars Christiansen, Mikhail Lemeshko, and Henrik Stapelfeldt. “Strongly Aligned Molecules inside Helium Droplets in the Near-Adiabatic Regime.” <i>The Journal of Chemical Physics</i>. AIP Publishing, 2017. <a href=\"https://doi.org/10.1063/1.4983703\">https://doi.org/10.1063/1.4983703</a>.","short":"B. Shepperson, A. Chatterley, A. Søndergaard, L. Christiansen, M. Lemeshko, H. Stapelfeldt, The Journal of Chemical Physics 147 (2017).","ista":"Shepperson B, Chatterley A, Søndergaard A, Christiansen L, Lemeshko M, Stapelfeldt H. 2017. Strongly aligned molecules inside helium droplets in the near-adiabatic regime. The Journal of Chemical Physics. 147(1), 013946.","ieee":"B. Shepperson, A. Chatterley, A. Søndergaard, L. Christiansen, M. Lemeshko, and H. Stapelfeldt, “Strongly aligned molecules inside helium droplets in the near-adiabatic regime,” <i>The Journal of Chemical Physics</i>, vol. 147, no. 1. AIP Publishing, 2017.","ama":"Shepperson B, Chatterley A, Søndergaard A, Christiansen L, Lemeshko M, Stapelfeldt H. Strongly aligned molecules inside helium droplets in the near-adiabatic regime. <i>The Journal of Chemical Physics</i>. 2017;147(1). doi:<a href=\"https://doi.org/10.1063/1.4983703\">10.1063/1.4983703</a>"},"main_file_link":[{"url":"https://arxiv.org/abs/1704.03684","open_access":"1"}],"year":"2017","_id":"996","oa":1,"title":"Strongly aligned molecules inside helium droplets in the near-adiabatic regime","publication":"The Journal of Chemical Physics","abstract":[{"lang":"eng","text":"Iodine (I 2  ) molecules embedded in He nanodroplets are aligned by a 160 ps long laser pulse. The highest degree of alignment, occurring at the peak of the pulse and quantified by ⟨cos 2 θ 2D ⟩ , is measured as a function of the laser intensity. The results are well described by ⟨cos 2 θ 2D ⟩  calculated for a gas of isolated molecules each with an effective rotational constant of 0.6 times the gas-phase value, and at a temperature of 0.4 K. Theoretical analysis using the angulon quasiparticle to describe rotating molecules in superfluid helium rationalizes why the alignment mechanism is similar to that of isolated molecules with an effective rotational constant. A major advantage of molecules in He droplets is that their 0.4 K temperature leads to stronger alignment than what can generally be achieved for gas phase molecules -- here demonstrated by a direct comparison of the droplet results to measurements on a ∼  1 K supersonic beam of isolated molecules. This point is further illustrated for more complex system by measurements on 1,4-diiodobenzene and 1,4-dibromobenzene. For all three molecular species studied the highest values of ⟨cos 2 θ 2D ⟩  achieved in He droplets exceed 0.96. "}],"publication_status":"published"},{"external_id":{"isi":["000417132100007"],"arxiv":["1705.05162"]},"date_published":"2017-12-06T00:00:00Z","scopus_import":"1","publication_identifier":{"issn":["0031-9007"]},"arxiv":1,"article_processing_charge":"No","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Preprint","type":"journal_article","date_updated":"2023-10-10T13:31:54Z","day":"06","ec_funded":1,"department":[{"_id":"MiLe"},{"_id":"RoSe"}],"doi":"10.1103/PhysRevLett.119.235301","language":[{"iso":"eng"}],"issue":"23","volume":119,"publisher":"American Physical Society","article_type":"original","intvolume":"       119","isi":1,"publist_id":"6401","month":"12","date_created":"2018-12-11T11:49:36Z","status":"public","article_number":"235301","citation":{"ista":"Yakaboylu E, Deuchert A, Lemeshko M. 2017. Emergence of non-abelian magnetic monopoles in a quantum impurity problem. Physical Review Letters. 119(23), 235301.","chicago":"Yakaboylu, Enderalp, Andreas Deuchert, and Mikhail Lemeshko. “Emergence of Non-Abelian Magnetic Monopoles in a Quantum Impurity Problem.” <i>Physical Review Letters</i>. American Physical Society, 2017. <a href=\"https://doi.org/10.1103/PhysRevLett.119.235301\">https://doi.org/10.1103/PhysRevLett.119.235301</a>.","short":"E. Yakaboylu, A. Deuchert, M. Lemeshko, Physical Review Letters 119 (2017).","ama":"Yakaboylu E, Deuchert A, Lemeshko M. Emergence of non-abelian magnetic monopoles in a quantum impurity problem. <i>Physical Review Letters</i>. 2017;119(23). doi:<a href=\"https://doi.org/10.1103/PhysRevLett.119.235301\">10.1103/PhysRevLett.119.235301</a>","ieee":"E. Yakaboylu, A. Deuchert, and M. Lemeshko, “Emergence of non-abelian magnetic monopoles in a quantum impurity problem,” <i>Physical Review Letters</i>, vol. 119, no. 23. American Physical Society, 2017.","mla":"Yakaboylu, Enderalp, et al. “Emergence of Non-Abelian Magnetic Monopoles in a Quantum Impurity Problem.” <i>Physical Review Letters</i>, vol. 119, no. 23, 235301, American Physical Society, 2017, doi:<a href=\"https://doi.org/10.1103/PhysRevLett.119.235301\">10.1103/PhysRevLett.119.235301</a>.","apa":"Yakaboylu, E., Deuchert, A., &#38; Lemeshko, M. (2017). Emergence of non-abelian magnetic monopoles in a quantum impurity problem. <i>Physical Review Letters</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevLett.119.235301\">https://doi.org/10.1103/PhysRevLett.119.235301</a>"},"main_file_link":[{"url":"https://arxiv.org/abs/1705.05162","open_access":"1"}],"quality_controlled":"1","author":[{"orcid":"0000-0001-5973-0874","full_name":"Yakaboylu, Enderalp","id":"38CB71F6-F248-11E8-B48F-1D18A9856A87","last_name":"Yakaboylu","first_name":"Enderalp"},{"first_name":"Andreas","last_name":"Deuchert","full_name":"Deuchert, Andreas","orcid":"0000-0003-3146-6746","id":"4DA65CD0-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Lemeshko","first_name":"Mikhail","id":"37CB05FA-F248-11E8-B48F-1D18A9856A87","full_name":"Lemeshko, Mikhail","orcid":"0000-0002-6990-7802"}],"year":"2017","publication":"Physical Review Letters","title":"Emergence of non-abelian magnetic monopoles in a quantum impurity problem","_id":"997","oa":1,"project":[{"name":"International IST Postdoc Fellowship Programme","grant_number":"291734","_id":"25681D80-B435-11E9-9278-68D0E5697425","call_identifier":"FP7"},{"name":"Analysis of quantum many-body systems","grant_number":"694227","_id":"25C6DC12-B435-11E9-9278-68D0E5697425","call_identifier":"H2020"},{"name":"Quantum rotations in the presence of a many-body environment","grant_number":"P29902","_id":"26031614-B435-11E9-9278-68D0E5697425","call_identifier":"FWF"}],"abstract":[{"lang":"eng","text":"Recently it was shown that molecules rotating in superfluid helium can be described in terms of the angulon quasiparticles (Phys. Rev. Lett. 118, 095301 (2017)). Here we demonstrate that in the experimentally realized regime the angulon can be seen as a point charge on a 2-sphere interacting with a gauge field of a non-abelian magnetic monopole. Unlike in several other settings, the gauge fields of the angulon problem emerge in the real coordinate space, as opposed to the momentum space or some effective parameter space. Furthermore, we find a topological transition associated with making the monopole abelian, which takes place in the vicinity of the previously reported angulon instabilities. These results pave the way for studying topological phenomena in experiments on molecules trapped in superfluid helium nanodroplets, as well as on other realizations of orbital impurity problems."}],"publication_status":"published"},{"volume":2017,"publisher":"IEEE","publist_id":"6400","isi":1,"intvolume":"      2017","status":"public","date_created":"2018-12-11T11:49:37Z","conference":{"end_date":"2017-07-26","name":"CVPR: Computer Vision and Pattern Recognition","start_date":"2017-07-21","location":"Honolulu, HA, United States"},"month":"04","quality_controlled":"1","author":[{"full_name":"Rebuffi, Sylvestre Alvise","last_name":"Rebuffi","first_name":"Sylvestre Alvise"},{"full_name":"Kolesnikov, Alexander","id":"2D157DB6-F248-11E8-B48F-1D18A9856A87","first_name":"Alexander","last_name":"Kolesnikov"},{"id":"4DD40360-F248-11E8-B48F-1D18A9856A87","full_name":"Sperl, Georg","last_name":"Sperl","first_name":"Georg"},{"first_name":"Christoph","last_name":"Lampert","id":"40C20FD2-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8622-7887","full_name":"Lampert, Christoph"}],"main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1611.07725"}],"citation":{"mla":"Rebuffi, Sylvestre Alvise, et al. <i>ICaRL: Incremental Classifier and Representation Learning</i>. Vol. 2017, IEEE, 2017, pp. 5533–42, doi:<a href=\"https://doi.org/10.1109/CVPR.2017.587\">10.1109/CVPR.2017.587</a>.","apa":"Rebuffi, S. A., Kolesnikov, A., Sperl, G., &#38; Lampert, C. (2017). iCaRL: Incremental classifier and representation learning (Vol. 2017, pp. 5533–5542). Presented at the CVPR: Computer Vision and Pattern Recognition, Honolulu, HA, United States: IEEE. <a href=\"https://doi.org/10.1109/CVPR.2017.587\">https://doi.org/10.1109/CVPR.2017.587</a>","ista":"Rebuffi SA, Kolesnikov A, Sperl G, Lampert C. 2017. iCaRL: Incremental classifier and representation learning. CVPR: Computer Vision and Pattern Recognition vol. 2017, 5533–5542.","chicago":"Rebuffi, Sylvestre Alvise, Alexander Kolesnikov, Georg Sperl, and Christoph Lampert. “ICaRL: Incremental Classifier and Representation Learning,” 2017:5533–42. IEEE, 2017. <a href=\"https://doi.org/10.1109/CVPR.2017.587\">https://doi.org/10.1109/CVPR.2017.587</a>.","short":"S.A. Rebuffi, A. Kolesnikov, G. Sperl, C. Lampert, in:, IEEE, 2017, pp. 5533–5542.","ieee":"S. A. Rebuffi, A. Kolesnikov, G. Sperl, and C. Lampert, “iCaRL: Incremental classifier and representation learning,” presented at the CVPR: Computer Vision and Pattern Recognition, Honolulu, HA, United States, 2017, vol. 2017, pp. 5533–5542.","ama":"Rebuffi SA, Kolesnikov A, Sperl G, Lampert C. iCaRL: Incremental classifier and representation learning. In: Vol 2017. IEEE; 2017:5533-5542. doi:<a href=\"https://doi.org/10.1109/CVPR.2017.587\">10.1109/CVPR.2017.587</a>"},"year":"2017","oa":1,"_id":"998","title":"iCaRL: Incremental classifier and representation learning","publication_status":"published","abstract":[{"lang":"eng","text":"A major open problem on the road to artificial intelligence is the development of incrementally learning systems that learn about more and more concepts over time from a stream of data. In this work, we introduce a new training strategy, iCaRL, that allows learning in such a class-incremental way: only the training data for a small number of classes has to be present at the same time and new classes can be added progressively. iCaRL learns strong classifiers and a data representation simultaneously. This distinguishes it from earlier works that were fundamentally limited to fixed data representations and therefore incompatible with deep learning architectures. We show by experiments on CIFAR-100 and ImageNet ILSVRC 2012 data that iCaRL can learn many classes incrementally over a long period of time where other strategies quickly fail. "}],"project":[{"call_identifier":"FP7","_id":"2532554C-B435-11E9-9278-68D0E5697425","grant_number":"308036","name":"Lifelong Learning of Visual Scene Understanding"}],"page":"5533 - 5542","date_published":"2017-04-14T00:00:00Z","external_id":{"isi":["000418371405066"]},"publication_identifier":{"isbn":["978-153860457-1"]},"scopus_import":"1","article_processing_charge":"No","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","day":"14","type":"conference","date_updated":"2023-09-22T09:51:58Z","oa_version":"Submitted Version","doi":"10.1109/CVPR.2017.587","language":[{"iso":"eng"}],"department":[{"_id":"ChLa"},{"_id":"ChWo"}],"ec_funded":1},{"language":[{"iso":"eng"}],"department":[{"_id":"ChLa"}],"ec_funded":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_processing_charge":"No","day":"08","date_updated":"2023-10-17T11:53:32Z","type":"conference","oa_version":"Submitted Version","publication_identifier":{"isbn":["9781510855144"]},"scopus_import":"1","alternative_title":["PMLR"],"page":"2807 - 2816","date_published":"2017-06-08T00:00:00Z","external_id":{"isi":["000683309502093"]},"oa":1,"_id":"999","title":"Multi-task learning with labeled and unlabeled tasks","publication_status":"published","abstract":[{"text":"In multi-task learning, a learner is given a collection of prediction tasks and needs to solve all of them. In contrast to previous work, which required that annotated training data must be available for all tasks, we consider a new setting, in which for some tasks, potentially most of them, only unlabeled training data is provided. Consequently, to solve all tasks, information must be transferred between tasks with labels and tasks without labels. Focusing on an instance-based transfer method we analyze two variants of this setting: when the set of labeled tasks is fixed, and when it can be actively selected by the learner. We state and prove a generalization bound that covers both scenarios and derive from it an algorithm for making the choice of labeled tasks (in the active case) and for transferring information between the tasks in a principled way. We also illustrate the effectiveness of the algorithm on synthetic and real data. ","lang":"eng"}],"project":[{"call_identifier":"FP7","_id":"2532554C-B435-11E9-9278-68D0E5697425","name":"Lifelong Learning of Visual Scene Understanding","grant_number":"308036"}],"author":[{"first_name":"Anastasia","last_name":"Pentina","id":"42E87FC6-F248-11E8-B48F-1D18A9856A87","full_name":"Pentina, Anastasia"},{"id":"40C20FD2-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8622-7887","full_name":"Lampert, Christoph","first_name":"Christoph","last_name":"Lampert"}],"quality_controlled":"1","citation":{"apa":"Pentina, A., &#38; Lampert, C. (2017). Multi-task learning with labeled and unlabeled tasks (Vol. 70, pp. 2807–2816). Presented at the ICML: International Conference on Machine Learning, Sydney, Australia: ML Research Press.","mla":"Pentina, Anastasia, and Christoph Lampert. <i>Multi-Task Learning with Labeled and Unlabeled Tasks</i>. Vol. 70, ML Research Press, 2017, pp. 2807–16.","short":"A. Pentina, C. Lampert, in:, ML Research Press, 2017, pp. 2807–2816.","chicago":"Pentina, Anastasia, and Christoph Lampert. “Multi-Task Learning with Labeled and Unlabeled Tasks,” 70:2807–16. ML Research Press, 2017.","ista":"Pentina A, Lampert C. 2017. Multi-task learning with labeled and unlabeled tasks. ICML: International Conference on Machine Learning, PMLR, vol. 70, 2807–2816.","ieee":"A. Pentina and C. Lampert, “Multi-task learning with labeled and unlabeled tasks,” presented at the ICML: International Conference on Machine Learning, Sydney, Australia, 2017, vol. 70, pp. 2807–2816.","ama":"Pentina A, Lampert C. Multi-task learning with labeled and unlabeled tasks. In: Vol 70. ML Research Press; 2017:2807-2816."},"main_file_link":[{"url":"https://arxiv.org/abs/1602.06518","open_access":"1"}],"year":"2017","publist_id":"6399","isi":1,"intvolume":"        70","status":"public","date_created":"2018-12-11T11:49:37Z","conference":{"name":"ICML: International Conference on Machine Learning","end_date":"2017-08-11","start_date":"2017-08-06","location":"Sydney, Australia"},"month":"06","volume":70,"publisher":"ML Research Press"},{"date_published":"2017-04-01T00:00:00Z","external_id":{"isi":["000398059200002"]},"page":"16 - 31","publication_identifier":{"issn":[" 0950382X"]},"scopus_import":"1","article_processing_charge":"No","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","date_updated":"2023-09-20T11:48:43Z","type":"journal_article","oa_version":"None","day":"01","language":[{"iso":"eng"}],"doi":"10.1111/mmi.13597","department":[{"_id":"CaGu"}],"issue":"1","volume":104,"publisher":"Wiley-Blackwell","intvolume":"       104","publist_id":"6294","isi":1,"date_created":"2018-12-11T11:50:03Z","month":"04","status":"public","citation":{"ama":"Fang C, Nagy-Staron AA, Grafe M, et al. Insulation and wiring specificity of BceR like response regulators and their target promoters in Bacillus subtilis. <i>Molecular Microbiology</i>. 2017;104(1):16-31. doi:<a href=\"https://doi.org/10.1111/mmi.13597\">10.1111/mmi.13597</a>","ieee":"C. Fang <i>et al.</i>, “Insulation and wiring specificity of BceR like response regulators and their target promoters in Bacillus subtilis,” <i>Molecular Microbiology</i>, vol. 104, no. 1. Wiley-Blackwell, pp. 16–31, 2017.","chicago":"Fang, Chong, Anna A Nagy-Staron, Martin Grafe, Ralf Heermann, Kirsten Jung, Susanne Gebhard, and Thorsten Mascher. “Insulation and Wiring Specificity of BceR like Response Regulators and Their Target Promoters in Bacillus Subtilis.” <i>Molecular Microbiology</i>. Wiley-Blackwell, 2017. <a href=\"https://doi.org/10.1111/mmi.13597\">https://doi.org/10.1111/mmi.13597</a>.","short":"C. Fang, A.A. Nagy-Staron, M. Grafe, R. Heermann, K. Jung, S. Gebhard, T. Mascher, Molecular Microbiology 104 (2017) 16–31.","ista":"Fang C, Nagy-Staron AA, Grafe M, Heermann R, Jung K, Gebhard S, Mascher T. 2017. Insulation and wiring specificity of BceR like response regulators and their target promoters in Bacillus subtilis. Molecular Microbiology. 104(1), 16–31.","mla":"Fang, Chong, et al. “Insulation and Wiring Specificity of BceR like Response Regulators and Their Target Promoters in Bacillus Subtilis.” <i>Molecular Microbiology</i>, vol. 104, no. 1, Wiley-Blackwell, 2017, pp. 16–31, doi:<a href=\"https://doi.org/10.1111/mmi.13597\">10.1111/mmi.13597</a>.","apa":"Fang, C., Nagy-Staron, A. A., Grafe, M., Heermann, R., Jung, K., Gebhard, S., &#38; Mascher, T. (2017). Insulation and wiring specificity of BceR like response regulators and their target promoters in Bacillus subtilis. <i>Molecular Microbiology</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1111/mmi.13597\">https://doi.org/10.1111/mmi.13597</a>"},"quality_controlled":"1","author":[{"last_name":"Fang","first_name":"Chong","full_name":"Fang, Chong"},{"full_name":"Nagy-Staron, Anna A","orcid":"0000-0002-1391-8377","id":"3ABC5BA6-F248-11E8-B48F-1D18A9856A87","last_name":"Nagy-Staron","first_name":"Anna A"},{"full_name":"Grafe, Martin","last_name":"Grafe","first_name":"Martin"},{"full_name":"Heermann, Ralf","last_name":"Heermann","first_name":"Ralf"},{"full_name":"Jung, Kirsten","last_name":"Jung","first_name":"Kirsten"},{"full_name":"Gebhard, Susanne","first_name":"Susanne","last_name":"Gebhard"},{"first_name":"Thorsten","last_name":"Mascher","full_name":"Mascher, Thorsten"}],"year":"2017","title":"Insulation and wiring specificity of BceR like response regulators and their target promoters in Bacillus subtilis","publication":"Molecular Microbiology","_id":"1084","publication_status":"published","abstract":[{"lang":"eng","text":"BceRS and PsdRS are paralogous two-component systems in Bacillus subtilis controlling the response to antimicrobial peptides. In the presence of extracellular bacitracin and nisin, respectively, the two response regulators (RRs) bind their target promoters, PbceA or PpsdA, resulting in a strong up-regulation of target gene expression and ultimately antibiotic resistance. Despite high sequence similarity between the RRs BceR and PsdR and their known binding sites, no cross-regulation has been observed between them. We therefore investigated the specificity determinants of PbceA and PpsdA that ensure the insulation of these two paralogous pathways at the RR–promoter interface. In vivo and in vitro analyses demonstrate that the regulatory regions within these two promoters contain three important elements: in addition to the known (main) binding site, we identified a linker region and a secondary binding site that are crucial for functionality. Initial binding to the high-affinity, low-specificity main binding site is a prerequisite for the subsequent highly specific binding of a second RR dimer to the low-affinity secondary binding site. In addition to this hierarchical cooperative binding, discrimination requires a competition of the two RRs for their respective binding site mediated by only slight differences in binding affinities."}]},{"month":"01","date_created":"2018-12-11T11:50:04Z","article_number":"14251","status":"public","intvolume":"         8","isi":1,"publist_id":"6292","file_date_updated":"2018-12-12T10:15:22Z","publisher":"Nature Publishing Group","pubrep_id":"791","volume":8,"abstract":[{"text":"Sex chromosomes evolve once recombination is halted between a homologous pair of chromosomes. The dominant model of sex chromosome evolution posits that recombination is suppressed between emerging X and Y chromosomes in order to resolve sexual conflict. Here we test this model using whole genome and transcriptome resequencing data in the guppy, a model for sexual selection with many Y-linked colour traits. We show that although the nascent Y chromosome encompasses nearly half of the linkage group, there has been no perceptible degradation of Y chromosome gene content or activity. Using replicate wild populations with differing levels of sexually antagonistic selection for colour, we also show that sexual selection leads to greater expansion of the non-recombining region and increased Y chromosome divergence. These results provide empirical support for longstanding models of sex chromosome catalysis, and suggest an important role for sexual selection and sexual conflict in genome evolution.","lang":"eng"}],"publication_status":"published","title":"Convergent recombination suppression suggests role of sexual selection in guppy sex chromosome formation","publication":"Nature Communications","_id":"1085","oa":1,"ddc":["570","576"],"tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"year":"2017","citation":{"mla":"Wright, Alison, et al. “Convergent Recombination Suppression Suggests Role of Sexual Selection in Guppy Sex Chromosome Formation.” <i>Nature Communications</i>, vol. 8, 14251, Nature Publishing Group, 2017, doi:<a href=\"https://doi.org/10.1038/ncomms14251\">10.1038/ncomms14251</a>.","apa":"Wright, A., Darolti, I., Bloch, N., Oostra, V., Sandkam, B., Buechel, S., … Mank, J. (2017). Convergent recombination suppression suggests role of sexual selection in guppy sex chromosome formation. <i>Nature Communications</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/ncomms14251\">https://doi.org/10.1038/ncomms14251</a>","ieee":"A. Wright <i>et al.</i>, “Convergent recombination suppression suggests role of sexual selection in guppy sex chromosome formation,” <i>Nature Communications</i>, vol. 8. Nature Publishing Group, 2017.","ama":"Wright A, Darolti I, Bloch N, et al. Convergent recombination suppression suggests role of sexual selection in guppy sex chromosome formation. <i>Nature Communications</i>. 2017;8. doi:<a href=\"https://doi.org/10.1038/ncomms14251\">10.1038/ncomms14251</a>","chicago":"Wright, Alison, Iulia Darolti, Natasha Bloch, Vicencio Oostra, Benjamin Sandkam, Séverine Buechel, Niclas Kolm, Felix Breden, Beatriz Vicoso, and Judith Mank. “Convergent Recombination Suppression Suggests Role of Sexual Selection in Guppy Sex Chromosome Formation.” <i>Nature Communications</i>. Nature Publishing Group, 2017. <a href=\"https://doi.org/10.1038/ncomms14251\">https://doi.org/10.1038/ncomms14251</a>.","short":"A. Wright, I. Darolti, N. Bloch, V. Oostra, B. Sandkam, S. Buechel, N. Kolm, F. Breden, B. Vicoso, J. Mank, Nature Communications 8 (2017).","ista":"Wright A, Darolti I, Bloch N, Oostra V, Sandkam B, Buechel S, Kolm N, Breden F, Vicoso B, Mank J. 2017. Convergent recombination suppression suggests role of sexual selection in guppy sex chromosome formation. Nature Communications. 8, 14251."},"quality_controlled":"1","author":[{"first_name":"Alison","last_name":"Wright","full_name":"Wright, Alison"},{"full_name":"Darolti, Iulia","last_name":"Darolti","first_name":"Iulia"},{"full_name":"Bloch, Natasha","last_name":"Bloch","first_name":"Natasha"},{"full_name":"Oostra, Vicencio","last_name":"Oostra","first_name":"Vicencio"},{"first_name":"Benjamin","last_name":"Sandkam","full_name":"Sandkam, Benjamin"},{"full_name":"Buechel, Séverine","first_name":"Séverine","last_name":"Buechel"},{"last_name":"Kolm","first_name":"Niclas","full_name":"Kolm, Niclas"},{"last_name":"Breden","first_name":"Felix","full_name":"Breden, Felix"},{"first_name":"Beatriz","last_name":"Vicoso","full_name":"Vicoso, Beatriz","orcid":"0000-0002-4579-8306","id":"49E1C5C6-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Mank","first_name":"Judith","full_name":"Mank, Judith"}],"scopus_import":"1","publication_identifier":{"issn":["20411723"]},"external_id":{"isi":["000392953700001"]},"file":[{"date_created":"2018-12-12T10:15:22Z","relation":"main_file","file_size":955256,"content_type":"application/pdf","creator":"system","file_id":"5141","date_updated":"2018-12-12T10:15:22Z","access_level":"open_access","file_name":"IST-2017-791-v1+1_ncomms14251.pdf"}],"date_published":"2017-01-31T00:00:00Z","has_accepted_license":"1","department":[{"_id":"BeVi"}],"language":[{"iso":"eng"}],"doi":"10.1038/ncomms14251","oa_version":"Published Version","date_updated":"2023-09-20T11:48:16Z","type":"journal_article","day":"31","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","article_processing_charge":"No"},{"scopus_import":"1","date_published":"2017-02-01T00:00:00Z","file":[{"file_id":"5115","date_updated":"2018-12-12T10:14:59Z","file_name":"IST-2017-790-v1+1_srep41002_1_.pdf","access_level":"open_access","relation":"main_file","date_created":"2018-12-12T10:14:59Z","file_size":1994139,"content_type":"application/pdf","creator":"system"}],"external_id":{"isi":["000393163800001"]},"page":"41002","doi":"10.1038/srep41002","language":[{"iso":"eng"}],"has_accepted_license":"1","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","article_processing_charge":"No","type":"journal_article","date_updated":"2023-09-20T11:47:47Z","oa_version":"Published Version","day":"01","intvolume":"         7","publist_id":"6291","isi":1,"date_created":"2018-12-11T11:50:04Z","month":"02","status":"public","volume":7,"pubrep_id":"790","file_date_updated":"2018-12-12T10:14:59Z","publisher":"Nature Publishing Group","publication":"Scientific Reports","title":"Development of a human vasopressin V1a-receptor antagonist from an evolutionary-related insect neuropeptide","oa":1,"ddc":["570","590"],"_id":"1086","publication_status":"published","abstract":[{"lang":"eng","text":"Characterisation of G protein-coupled receptors (GPCR) relies on the availability of a toolbox of ligands that selectively modulate different functional states of the receptors. To uncover such molecules, we explored a unique strategy for ligand discovery that takes advantage of the evolutionary conservation of the 600-million-year-old oxytocin/vasopressin signalling system. We isolated the insect oxytocin/vasopressin orthologue inotocin from the black garden ant (Lasius niger), identified and cloned its cognate receptor and determined its pharmacological properties on the insect and human oxytocin/vasopressin receptors. Subsequently, we identified a functional dichotomy: inotocin activated the insect inotocin and the human vasopressin V1b receptors, but inhibited the human V1aR. Replacement of Arg8 of inotocin by D-Arg8 led to a potent, stable and competitive V1aR-antagonist ([D-Arg8]-inotocin) with a 3,000-fold binding selectivity for the human V1aR over the other three subtypes, OTR, V1bR and V2R. The Arg8/D-Arg8 ligand-pair was further investigated to gain novel insights into the oxytocin/vasopressin peptide-receptor interaction, which led to the identification of key residues of the receptors that are important for ligand functionality and selectivity. These observations could play an important role for development of oxytocin/vasopressin receptor modulators that would enable clear distinction of the physiological and pathological responses of the individual receptor subtypes."}],"citation":{"mla":"Di Giglio, Maria, et al. “Development of a Human Vasopressin V1a-Receptor Antagonist from an Evolutionary-Related Insect Neuropeptide.” <i>Scientific Reports</i>, vol. 7, Nature Publishing Group, 2017, p. 41002, doi:<a href=\"https://doi.org/10.1038/srep41002\">10.1038/srep41002</a>.","apa":"Di Giglio, M., Muttenthaler, M., Harpsøe, K., Liutkeviciute, Z., Keov, P., Eder, T., … Gruber, C. (2017). Development of a human vasopressin V1a-receptor antagonist from an evolutionary-related insect neuropeptide. <i>Scientific Reports</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/srep41002\">https://doi.org/10.1038/srep41002</a>","ama":"Di Giglio M, Muttenthaler M, Harpsøe K, et al. Development of a human vasopressin V1a-receptor antagonist from an evolutionary-related insect neuropeptide. <i>Scientific Reports</i>. 2017;7:41002. doi:<a href=\"https://doi.org/10.1038/srep41002\">10.1038/srep41002</a>","ieee":"M. Di Giglio <i>et al.</i>, “Development of a human vasopressin V1a-receptor antagonist from an evolutionary-related insect neuropeptide,” <i>Scientific Reports</i>, vol. 7. Nature Publishing Group, p. 41002, 2017.","short":"M. Di Giglio, M. Muttenthaler, K. Harpsøe, Z. Liutkeviciute, P. Keov, T. Eder, T. Rattei, S. Arrowsmith, S. Wray, A. Marek, T. Elbert, P. Alewood, D. Gloriam, C. Gruber, Scientific Reports 7 (2017) 41002.","chicago":"Di Giglio, Maria, Markus Muttenthaler, Kasper Harpsøe, Zita Liutkeviciute, Peter Keov, Thomas Eder, Thomas Rattei, et al. “Development of a Human Vasopressin V1a-Receptor Antagonist from an Evolutionary-Related Insect Neuropeptide.” <i>Scientific Reports</i>. Nature Publishing Group, 2017. <a href=\"https://doi.org/10.1038/srep41002\">https://doi.org/10.1038/srep41002</a>.","ista":"Di Giglio M, Muttenthaler M, Harpsøe K, Liutkeviciute Z, Keov P, Eder T, Rattei T, Arrowsmith S, Wray S, Marek A, Elbert T, Alewood P, Gloriam D, Gruber C. 2017. Development of a human vasopressin V1a-receptor antagonist from an evolutionary-related insect neuropeptide. Scientific Reports. 7, 41002."},"quality_controlled":"1","author":[{"full_name":"Di Giglio, Maria","first_name":"Maria","last_name":"Di Giglio"},{"first_name":"Markus","last_name":"Muttenthaler","full_name":"Muttenthaler, Markus"},{"full_name":"Harpsøe, Kasper","first_name":"Kasper","last_name":"Harpsøe"},{"first_name":"Zita","last_name":"Liutkeviciute","full_name":"Liutkeviciute, Zita"},{"last_name":"Keov","first_name":"Peter","full_name":"Keov, Peter"},{"first_name":"Thomas","last_name":"Eder","full_name":"Eder, Thomas"},{"first_name":"Thomas","last_name":"Rattei","full_name":"Rattei, Thomas"},{"last_name":"Arrowsmith","first_name":"Sarah","full_name":"Arrowsmith, Sarah"},{"last_name":"Wray","first_name":"Susan","full_name":"Wray, Susan"},{"full_name":"Marek, Ales","last_name":"Marek","first_name":"Ales"},{"full_name":"Elbert, Tomas","first_name":"Tomas","last_name":"Elbert"},{"last_name":"Alewood","first_name":"Paul","full_name":"Alewood, Paul"},{"full_name":"Gloriam, David","first_name":"David","last_name":"Gloriam"},{"full_name":"Gruber, Christian","last_name":"Gruber","first_name":"Christian"}],"tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"year":"2017"},{"author":[{"full_name":"Song, Baofang","first_name":"Baofang","last_name":"Song"},{"first_name":"Dwight","last_name":"Barkley","full_name":"Barkley, Dwight"},{"last_name":"Hof","first_name":"Björn","id":"3A374330-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-2057-2754","full_name":"Hof, Björn"},{"first_name":"Marc","last_name":"Avila","full_name":"Avila, Marc"}],"quality_controlled":"1","citation":{"ama":"Song B, Barkley D, Hof B, Avila M. Speed and structure of turbulent fronts in pipe flow. <i>Journal of Fluid Mechanics</i>. 2017;813:1045-1059. doi:<a href=\"https://doi.org/10.1017/jfm.2017.14\">10.1017/jfm.2017.14</a>","ieee":"B. Song, D. Barkley, B. Hof, and M. Avila, “Speed and structure of turbulent fronts in pipe flow,” <i>Journal of Fluid Mechanics</i>, vol. 813. Cambridge University Press, pp. 1045–1059, 2017.","short":"B. Song, D. Barkley, B. Hof, M. Avila, Journal of Fluid Mechanics 813 (2017) 1045–1059.","chicago":"Song, Baofang, Dwight Barkley, Björn Hof, and Marc Avila. “Speed and Structure of Turbulent Fronts in Pipe Flow.” <i>Journal of Fluid Mechanics</i>. Cambridge University Press, 2017. <a href=\"https://doi.org/10.1017/jfm.2017.14\">https://doi.org/10.1017/jfm.2017.14</a>.","ista":"Song B, Barkley D, Hof B, Avila M. 2017. Speed and structure of turbulent fronts in pipe flow. Journal of Fluid Mechanics. 813, 1045–1059.","apa":"Song, B., Barkley, D., Hof, B., &#38; Avila, M. (2017). Speed and structure of turbulent fronts in pipe flow. <i>Journal of Fluid Mechanics</i>. Cambridge University Press. <a href=\"https://doi.org/10.1017/jfm.2017.14\">https://doi.org/10.1017/jfm.2017.14</a>","mla":"Song, Baofang, et al. “Speed and Structure of Turbulent Fronts in Pipe Flow.” <i>Journal of Fluid Mechanics</i>, vol. 813, Cambridge University Press, 2017, pp. 1045–59, doi:<a href=\"https://doi.org/10.1017/jfm.2017.14\">10.1017/jfm.2017.14</a>."},"main_file_link":[{"url":"https://arxiv.org/abs/1603.04077","open_access":"1"}],"year":"2017","_id":"1087","oa":1,"publication":"Journal of Fluid Mechanics","title":"Speed and structure of turbulent fronts in pipe flow","abstract":[{"text":"Using extensive direct numerical simulations, the dynamics of laminar-turbulent fronts in pipe flow is investigated for Reynolds numbers between and 5500. We here investigate the physical distinction between the fronts of weak and strong slugs both by analysing the turbulent kinetic energy budget and by comparing the downstream front motion to the advection speed of bulk turbulent structures. Our study shows that weak downstream fronts travel slower than turbulent structures in the bulk and correspond to decaying turbulence at the front. At the downstream front speed becomes faster than the advection speed, marking the onset of strong fronts. In contrast to weak fronts, turbulent eddies are generated at strong fronts by feeding on the downstream laminar flow. Our study also suggests that temporal fluctuations of production and dissipation at the downstream laminar-turbulent front drive the dynamical switches between the two types of front observed up to.","lang":"eng"}],"publication_status":"published","project":[{"name":"Decoding the complexity of turbulence at its origin","grant_number":"306589","call_identifier":"FP7","_id":"25152F3A-B435-11E9-9278-68D0E5697425"}],"volume":813,"publisher":"Cambridge University Press","isi":1,"publist_id":"6290","intvolume":"       813","status":"public","month":"02","date_created":"2018-12-11T11:50:04Z","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","article_processing_charge":"No","day":"25","oa_version":"Submitted Version","date_updated":"2023-09-20T11:47:22Z","type":"journal_article","department":[{"_id":"BjHo"}],"doi":"10.1017/jfm.2017.14","language":[{"iso":"eng"}],"acknowledged_ssus":[{"_id":"ScienComp"}],"ec_funded":1,"page":"1045 - 1059","external_id":{"isi":["000394376400044"]},"date_published":"2017-02-25T00:00:00Z","scopus_import":"1","publication_identifier":{"issn":["00221120"]}},{"publisher":"Institute of Mathematical Statistics","issue":"3","volume":45,"month":"06","date_created":"2018-12-11T11:50:05Z","status":"public","intvolume":"        45","isi":1,"publist_id":"6288","year":"2017","main_file_link":[{"url":"https://arxiv.org/abs/1510.01290","open_access":"1"}],"citation":{"short":"S. Fallat, S. Lauritzen, K. Sadeghi, C. Uhler, N. Wermuth, P. Zwiernik, Annals of Statistics 45 (2017) 1152–1184.","chicago":"Fallat, Shaun, Steffen Lauritzen, Kayvan Sadeghi, Caroline Uhler, Nanny Wermuth, and Piotr Zwiernik. “Total Positivity in Markov Structures.” <i>Annals of Statistics</i>. Institute of Mathematical Statistics, 2017. <a href=\"https://doi.org/10.1214/16-AOS1478\">https://doi.org/10.1214/16-AOS1478</a>.","ista":"Fallat S, Lauritzen S, Sadeghi K, Uhler C, Wermuth N, Zwiernik P. 2017. Total positivity in Markov structures. Annals of Statistics. 45(3), 1152–1184.","ieee":"S. Fallat, S. Lauritzen, K. Sadeghi, C. Uhler, N. Wermuth, and P. Zwiernik, “Total positivity in Markov structures,” <i>Annals of Statistics</i>, vol. 45, no. 3. Institute of Mathematical Statistics, pp. 1152–1184, 2017.","ama":"Fallat S, Lauritzen S, Sadeghi K, Uhler C, Wermuth N, Zwiernik P. Total positivity in Markov structures. <i>Annals of Statistics</i>. 2017;45(3):1152-1184. doi:<a href=\"https://doi.org/10.1214/16-AOS1478\">10.1214/16-AOS1478</a>","apa":"Fallat, S., Lauritzen, S., Sadeghi, K., Uhler, C., Wermuth, N., &#38; Zwiernik, P. (2017). Total positivity in Markov structures. <i>Annals of Statistics</i>. Institute of Mathematical Statistics. <a href=\"https://doi.org/10.1214/16-AOS1478\">https://doi.org/10.1214/16-AOS1478</a>","mla":"Fallat, Shaun, et al. “Total Positivity in Markov Structures.” <i>Annals of Statistics</i>, vol. 45, no. 3, Institute of Mathematical Statistics, 2017, pp. 1152–84, doi:<a href=\"https://doi.org/10.1214/16-AOS1478\">10.1214/16-AOS1478</a>."},"author":[{"first_name":"Shaun","last_name":"Fallat","full_name":"Fallat, Shaun"},{"full_name":"Lauritzen, Steffen","last_name":"Lauritzen","first_name":"Steffen"},{"first_name":"Kayvan","last_name":"Sadeghi","full_name":"Sadeghi, Kayvan"},{"full_name":"Uhler, Caroline","orcid":"0000-0002-7008-0216","id":"49ADD78E-F248-11E8-B48F-1D18A9856A87","first_name":"Caroline","last_name":"Uhler"},{"full_name":"Wermuth, Nanny","last_name":"Wermuth","first_name":"Nanny"},{"last_name":"Zwiernik","first_name":"Piotr","full_name":"Zwiernik, Piotr"}],"quality_controlled":"1","project":[{"name":"Gaussian Graphical Models: Theory and Applications","grant_number":"Y 903-N35","call_identifier":"FWF","_id":"2530CA10-B435-11E9-9278-68D0E5697425"}],"abstract":[{"text":"We discuss properties of distributions that are multivariate totally positive of order two (MTP2) related to conditional independence. In particular, we show that any independence model generated by an MTP2 distribution is a compositional semigraphoid which is upward-stable and singleton-transitive. In addition, we prove that any MTP2 distribution satisfying an appropriate support condition is faithful to its concentration graph. Finally, we analyze factorization properties of MTP2 distributions and discuss ways of constructing MTP2 distributions; in particular we give conditions on the log-linear parameters of a discrete distribution which ensure MTP2 and characterize conditional Gaussian distributions which satisfy MTP2.","lang":"eng"}],"publication_status":"published","publication":"Annals of Statistics","title":"Total positivity in Markov structures","_id":"1089","oa":1,"external_id":{"isi":["000404395900008"]},"date_published":"2017-06-01T00:00:00Z","page":"1152 - 1184","scopus_import":"1","publication_identifier":{"issn":["00905364"]},"oa_version":"Submitted Version","date_updated":"2023-09-20T11:46:53Z","type":"journal_article","day":"01","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","article_processing_charge":"No","department":[{"_id":"CaUh"}],"language":[{"iso":"eng"}],"doi":"10.1214/16-AOS1478"},{"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","article_processing_charge":"No","oa_version":"Published Version","date_updated":"2023-09-20T11:41:19Z","type":"journal_article","day":"06","ec_funded":1,"has_accepted_license":"1","department":[{"_id":"GaTk"}],"language":[{"iso":"eng"}],"doi":"10.1038/s41467-017-02159-y","external_id":{"isi":["000417241200004"]},"file":[{"creator":"system","content_type":"application/pdf","file_size":2872887,"relation":"main_file","date_created":"2018-12-12T10:16:06Z","file_name":"IST-2018-921-v1+1_s41467-017-02159-y.pdf","access_level":"open_access","date_updated":"2018-12-12T10:16:06Z","file_id":"5191"}],"date_published":"2017-12-06T00:00:00Z","scopus_import":"1","publication_identifier":{"issn":["20411723"]},"citation":{"apa":"Deny, S., Ferrari, U., Mace, E., Yger, P., Caplette, R., Picaud, S., … Marre, O. (2017). Multiplexed computations in retinal ganglion cells of a single type. <i>Nature Communications</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/s41467-017-02159-y\">https://doi.org/10.1038/s41467-017-02159-y</a>","mla":"Deny, Stephane, et al. “Multiplexed Computations in Retinal Ganglion Cells of a Single Type.” <i>Nature Communications</i>, vol. 8, no. 1, 1964, Nature Publishing Group, 2017, doi:<a href=\"https://doi.org/10.1038/s41467-017-02159-y\">10.1038/s41467-017-02159-y</a>.","ista":"Deny S, Ferrari U, Mace E, Yger P, Caplette R, Picaud S, Tkačik G, Marre O. 2017. Multiplexed computations in retinal ganglion cells of a single type. Nature Communications. 8(1), 1964.","short":"S. Deny, U. Ferrari, E. Mace, P. Yger, R. Caplette, S. Picaud, G. Tkačik, O. Marre, Nature Communications 8 (2017).","chicago":"Deny, Stephane, Ulisse Ferrari, Emilie Mace, Pierre Yger, Romain Caplette, Serge Picaud, Gašper Tkačik, and Olivier Marre. “Multiplexed Computations in Retinal Ganglion Cells of a Single Type.” <i>Nature Communications</i>. Nature Publishing Group, 2017. <a href=\"https://doi.org/10.1038/s41467-017-02159-y\">https://doi.org/10.1038/s41467-017-02159-y</a>.","ama":"Deny S, Ferrari U, Mace E, et al. Multiplexed computations in retinal ganglion cells of a single type. <i>Nature Communications</i>. 2017;8(1). doi:<a href=\"https://doi.org/10.1038/s41467-017-02159-y\">10.1038/s41467-017-02159-y</a>","ieee":"S. Deny <i>et al.</i>, “Multiplexed computations in retinal ganglion cells of a single type,” <i>Nature Communications</i>, vol. 8, no. 1. Nature Publishing Group, 2017."},"author":[{"last_name":"Deny","first_name":"Stephane","full_name":"Deny, Stephane"},{"last_name":"Ferrari","first_name":"Ulisse","full_name":"Ferrari, Ulisse"},{"first_name":"Emilie","last_name":"Mace","full_name":"Mace, Emilie"},{"last_name":"Yger","first_name":"Pierre","full_name":"Yger, Pierre"},{"full_name":"Caplette, Romain","first_name":"Romain","last_name":"Caplette"},{"full_name":"Picaud, Serge","first_name":"Serge","last_name":"Picaud"},{"id":"3D494DCA-F248-11E8-B48F-1D18A9856A87","full_name":"Tkacik, Gasper","orcid":"0000-0002-6699-1455","first_name":"Gasper","last_name":"Tkacik"},{"full_name":"Marre, Olivier","last_name":"Marre","first_name":"Olivier"}],"quality_controlled":"1","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"year":"2017","title":"Multiplexed computations in retinal ganglion cells of a single type","publication":"Nature Communications","_id":"1104","ddc":["571"],"oa":1,"project":[{"name":"Localization of ion channels and receptors by two and three-dimensional immunoelectron microscopic approaches","grant_number":"604102","call_identifier":"FP7","_id":"25CD3DD2-B435-11E9-9278-68D0E5697425"},{"_id":"254D1A94-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","grant_number":"P 25651-N26","name":"Sensitivity to higher-order statistics in natural scenes"}],"abstract":[{"lang":"eng","text":"In the early visual system, cells of the same type perform the same computation in different places of the visual field. How these cells code together a complex visual scene is unclear. A common assumption is that cells of a single-type extract a single-stimulus feature to form a feature map, but this has rarely been observed directly. Using large-scale recordings in the rat retina, we show that a homogeneous population of fast OFF ganglion cells simultaneously encodes two radically different features of a visual scene. Cells close to a moving object code quasilinearly for its position, while distant cells remain largely invariant to the object's position and, instead, respond nonlinearly to changes in the object's speed. We develop a quantitative model that accounts for this effect and identify a disinhibitory circuit that mediates it. Ganglion cells of a single type thus do not code for one, but two features simultaneously. This richer, flexible neural map might also be present in other sensory systems."}],"publication_status":"published","pubrep_id":"921","issue":"1","volume":8,"file_date_updated":"2018-12-12T10:16:06Z","publisher":"Nature Publishing Group","intvolume":"         8","isi":1,"publist_id":"6266","month":"12","date_created":"2018-12-11T11:50:10Z","article_number":"1964","status":"public"},{"date_published":"2017-08-30T00:00:00Z","external_id":{"pmid":["28855503"]},"keyword":["General Physics and Astronomy","General Biochemistry","Genetics and Molecular Biology","General Chemistry"],"publication_identifier":{"issn":["2041-1723"]},"scopus_import":"1","article_processing_charge":"No","user_id":"72615eeb-f1f3-11ec-aa25-d4573ddc34fd","date_updated":"2022-07-18T08:33:03Z","type":"journal_article","oa_version":"Published Version","day":"30","language":[{"iso":"eng"}],"doi":"10.1038/s41467-017-00322-z","volume":8,"publisher":"Springer Nature","article_type":"original","intvolume":"         8","date_created":"2022-04-07T07:45:50Z","month":"08","status":"public","article_number":"328","citation":{"mla":"Buchwalter, Abigail, and Martin Hetzer. “Nucleolar Expansion and Elevated Protein Translation in Premature Aging.” <i>Nature Communications</i>, vol. 8, 328, Springer Nature, 2017, doi:<a href=\"https://doi.org/10.1038/s41467-017-00322-z\">10.1038/s41467-017-00322-z</a>.","apa":"Buchwalter, A., &#38; Hetzer, M. (2017). Nucleolar expansion and elevated protein translation in premature aging. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-017-00322-z\">https://doi.org/10.1038/s41467-017-00322-z</a>","short":"A. Buchwalter, M. Hetzer, Nature Communications 8 (2017).","chicago":"Buchwalter, Abigail, and Martin Hetzer. “Nucleolar Expansion and Elevated Protein Translation in Premature Aging.” <i>Nature Communications</i>. Springer Nature, 2017. <a href=\"https://doi.org/10.1038/s41467-017-00322-z\">https://doi.org/10.1038/s41467-017-00322-z</a>.","ista":"Buchwalter A, Hetzer M. 2017. Nucleolar expansion and elevated protein translation in premature aging. Nature Communications. 8, 328.","ama":"Buchwalter A, Hetzer M. Nucleolar expansion and elevated protein translation in premature aging. <i>Nature Communications</i>. 2017;8. doi:<a href=\"https://doi.org/10.1038/s41467-017-00322-z\">10.1038/s41467-017-00322-z</a>","ieee":"A. Buchwalter and M. Hetzer, “Nucleolar expansion and elevated protein translation in premature aging,” <i>Nature Communications</i>, vol. 8. Springer Nature, 2017."},"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1038/s41467-017-00322-z"}],"quality_controlled":"1","extern":"1","author":[{"full_name":"Buchwalter, Abigail","first_name":"Abigail","last_name":"Buchwalter"},{"id":"86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed","orcid":"0000-0002-2111-992X","full_name":"HETZER, Martin W","last_name":"HETZER","first_name":"Martin W"}],"year":"2017","title":"Nucleolar expansion and elevated protein translation in premature aging","publication":"Nature Communications","pmid":1,"oa":1,"_id":"11065","publication_status":"published","abstract":[{"text":"Premature aging disorders provide an opportunity to study the mechanisms that drive aging. In Hutchinson-Gilford progeria syndrome (HGPS), a mutant form of the nuclear scaffold protein lamin A distorts nuclei and sequesters nuclear proteins. We sought to investigate protein homeostasis in this disease. Here, we report a widespread increase in protein turnover in HGPS-derived cells compared to normal cells. We determine that global protein synthesis is elevated as a consequence of activated nucleoli and enhanced ribosome biogenesis in HGPS-derived fibroblasts. Depleting normal lamin A or inducing mutant lamin A expression are each sufficient to drive nucleolar expansion. We further show that nucleolar size correlates with donor age in primary fibroblasts derived from healthy individuals and that ribosomal RNA production increases with age, indicating that nucleolar size and activity can serve as aging biomarkers. While limiting ribosome biogenesis extends lifespan in several systems, we show that increased ribosome biogenesis and activity are a hallmark of premature aging.","lang":"eng"}]},{"external_id":{"pmid":["29269482"]},"keyword":["Developmental Biology","Genetics"],"date_published":"2017-12-21T00:00:00Z","page":"2222-2234","scopus_import":"1","publication_identifier":{"issn":["0890-9369","1549-5477"]},"oa_version":"Published Version","type":"journal_article","date_updated":"2022-07-18T08:33:05Z","day":"21","article_processing_charge":"No","user_id":"72615eeb-f1f3-11ec-aa25-d4573ddc34fd","language":[{"iso":"eng"}],"doi":"10.1101/gad.306753.117","article_type":"original","publisher":"Cold Spring Harbor Laboratory","issue":"22","volume":31,"month":"12","date_created":"2022-04-07T07:45:59Z","status":"public","intvolume":"        31","year":"2017","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1101/gad.306753.117"}],"citation":{"mla":"Franks, Tobias M., et al. “Nup98 Recruits the Wdr82–Set1A/COMPASS Complex to Promoters to Regulate H3K4 Trimethylation in Hematopoietic Progenitor Cells.” <i>Genes &#38; Development</i>, vol. 31, no. 22, Cold Spring Harbor Laboratory, 2017, pp. 2222–34, doi:<a href=\"https://doi.org/10.1101/gad.306753.117\">10.1101/gad.306753.117</a>.","apa":"Franks, T. M., McCloskey, A., Shokhirev, M. N., Benner, C., Rathore, A., &#38; Hetzer, M. (2017). Nup98 recruits the Wdr82–Set1A/COMPASS complex to promoters to regulate H3K4 trimethylation in hematopoietic progenitor cells. <i>Genes &#38; Development</i>. Cold Spring Harbor Laboratory. <a href=\"https://doi.org/10.1101/gad.306753.117\">https://doi.org/10.1101/gad.306753.117</a>","chicago":"Franks, Tobias M., Asako McCloskey, Maxim Nikolaievich Shokhirev, Chris Benner, Annie Rathore, and Martin Hetzer. “Nup98 Recruits the Wdr82–Set1A/COMPASS Complex to Promoters to Regulate H3K4 Trimethylation in Hematopoietic Progenitor Cells.” <i>Genes &#38; Development</i>. Cold Spring Harbor Laboratory, 2017. <a href=\"https://doi.org/10.1101/gad.306753.117\">https://doi.org/10.1101/gad.306753.117</a>.","short":"T.M. Franks, A. McCloskey, M.N. Shokhirev, C. Benner, A. Rathore, M. Hetzer, Genes &#38; Development 31 (2017) 2222–2234.","ista":"Franks TM, McCloskey A, Shokhirev MN, Benner C, Rathore A, Hetzer M. 2017. Nup98 recruits the Wdr82–Set1A/COMPASS complex to promoters to regulate H3K4 trimethylation in hematopoietic progenitor cells. Genes &#38; Development. 31(22), 2222–2234.","ieee":"T. M. Franks, A. McCloskey, M. N. Shokhirev, C. Benner, A. Rathore, and M. Hetzer, “Nup98 recruits the Wdr82–Set1A/COMPASS complex to promoters to regulate H3K4 trimethylation in hematopoietic progenitor cells,” <i>Genes &#38; Development</i>, vol. 31, no. 22. Cold Spring Harbor Laboratory, pp. 2222–2234, 2017.","ama":"Franks TM, McCloskey A, Shokhirev MN, Benner C, Rathore A, Hetzer M. Nup98 recruits the Wdr82–Set1A/COMPASS complex to promoters to regulate H3K4 trimethylation in hematopoietic progenitor cells. <i>Genes &#38; Development</i>. 2017;31(22):2222-2234. doi:<a href=\"https://doi.org/10.1101/gad.306753.117\">10.1101/gad.306753.117</a>"},"quality_controlled":"1","author":[{"full_name":"Franks, Tobias M.","last_name":"Franks","first_name":"Tobias M."},{"first_name":"Asako","last_name":"McCloskey","full_name":"McCloskey, Asako"},{"full_name":"Shokhirev, Maxim Nikolaievich","last_name":"Shokhirev","first_name":"Maxim Nikolaievich"},{"last_name":"Benner","first_name":"Chris","full_name":"Benner, Chris"},{"full_name":"Rathore, Annie","last_name":"Rathore","first_name":"Annie"},{"id":"86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed","full_name":"HETZER, Martin W","orcid":"0000-0002-2111-992X","last_name":"HETZER","first_name":"Martin W"}],"extern":"1","abstract":[{"text":"Recent studies have shown that a subset of nucleoporins (Nups) can detach from the nuclear pore complex and move into the nuclear interior to regulate transcription. One such dynamic Nup, called Nup98, has been implicated in gene activation in healthy cells and has been shown to drive leukemogenesis when mutated in patients with acute myeloid leukemia (AML). Here we show that in hematopoietic cells, Nup98 binds predominantly to transcription start sites to recruit the Wdr82–Set1A/COMPASS (complex of proteins associated with Set1) complex, which is required for deposition of the histone 3 Lys4 trimethyl (H3K4me3)-activating mark. Depletion of Nup98 or Wdr82 abolishes Set1A recruitment to chromatin and subsequently ablates H3K4me3 at adjacent promoters. Furthermore, expression of a Nup98 fusion protein implicated in aggressive AML causes mislocalization of H3K4me3 at abnormal regions and up-regulation of associated genes. Our findings establish a function of Nup98 in hematopoietic gene activation and provide mechanistic insight into which Nup98 leukemic fusion proteins promote AML.","lang":"eng"}],"publication_status":"published","pmid":1,"publication":"Genes & Development","title":"Nup98 recruits the Wdr82–Set1A/COMPASS complex to promoters to regulate H3K4 trimethylation in hematopoietic progenitor cells","_id":"11066","oa":1},{"page":"618-634.e7","external_id":{"pmid":["28919367"]},"keyword":["Cell Biology","Genetics","Molecular Medicine"],"date_published":"2017-11-02T00:00:00Z","scopus_import":"1","publication_identifier":{"issn":["1934-5909"]},"day":"02","oa_version":"Published Version","type":"journal_article","date_updated":"2022-07-18T08:33:07Z","article_processing_charge":"No","user_id":"72615eeb-f1f3-11ec-aa25-d4573ddc34fd","language":[{"iso":"eng"}],"doi":"10.1016/j.stem.2017.08.012","article_type":"original","publisher":"Elsevier","volume":21,"issue":"5","status":"public","month":"11","date_created":"2022-04-07T07:46:12Z","intvolume":"        21","year":"2017","extern":"1","quality_controlled":"1","author":[{"full_name":"Toda, Tomohisa","last_name":"Toda","first_name":"Tomohisa"},{"last_name":"Hsu","first_name":"Jonathan Y.","full_name":"Hsu, Jonathan Y."},{"last_name":"Linker","first_name":"Sara B.","full_name":"Linker, Sara B."},{"first_name":"Lauren","last_name":"Hu","full_name":"Hu, Lauren"},{"full_name":"Schafer, Simon T.","last_name":"Schafer","first_name":"Simon T."},{"last_name":"Mertens","first_name":"Jerome","full_name":"Mertens, Jerome"},{"last_name":"Jacinto","first_name":"Filipe V.","full_name":"Jacinto, Filipe V."},{"id":"86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed","full_name":"HETZER, Martin W","orcid":"0000-0002-2111-992X","first_name":"Martin W","last_name":"HETZER"},{"full_name":"Gage, Fred H.","last_name":"Gage","first_name":"Fred H."}],"main_file_link":[{"url":"https://doi.org/10.1016/j.stem.2017.08.012","open_access":"1"}],"citation":{"apa":"Toda, T., Hsu, J. Y., Linker, S. B., Hu, L., Schafer, S. T., Mertens, J., … Gage, F. H. (2017). Nup153 interacts with Sox2 to enable bimodal gene regulation and maintenance of neural progenitor cells. <i>Cell Stem Cell</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.stem.2017.08.012\">https://doi.org/10.1016/j.stem.2017.08.012</a>","mla":"Toda, Tomohisa, et al. “Nup153 Interacts with Sox2 to Enable Bimodal Gene Regulation and Maintenance of Neural Progenitor Cells.” <i>Cell Stem Cell</i>, vol. 21, no. 5, Elsevier, 2017, p. 618–634.e7, doi:<a href=\"https://doi.org/10.1016/j.stem.2017.08.012\">10.1016/j.stem.2017.08.012</a>.","ieee":"T. Toda <i>et al.</i>, “Nup153 interacts with Sox2 to enable bimodal gene regulation and maintenance of neural progenitor cells,” <i>Cell Stem Cell</i>, vol. 21, no. 5. Elsevier, p. 618–634.e7, 2017.","ama":"Toda T, Hsu JY, Linker SB, et al. Nup153 interacts with Sox2 to enable bimodal gene regulation and maintenance of neural progenitor cells. <i>Cell Stem Cell</i>. 2017;21(5):618-634.e7. doi:<a href=\"https://doi.org/10.1016/j.stem.2017.08.012\">10.1016/j.stem.2017.08.012</a>","short":"T. Toda, J.Y. Hsu, S.B. Linker, L. Hu, S.T. Schafer, J. Mertens, F.V. Jacinto, M. Hetzer, F.H. Gage, Cell Stem Cell 21 (2017) 618–634.e7.","chicago":"Toda, Tomohisa, Jonathan Y. Hsu, Sara B. Linker, Lauren Hu, Simon T. Schafer, Jerome Mertens, Filipe V. Jacinto, Martin Hetzer, and Fred H. Gage. “Nup153 Interacts with Sox2 to Enable Bimodal Gene Regulation and Maintenance of Neural Progenitor Cells.” <i>Cell Stem Cell</i>. Elsevier, 2017. <a href=\"https://doi.org/10.1016/j.stem.2017.08.012\">https://doi.org/10.1016/j.stem.2017.08.012</a>.","ista":"Toda T, Hsu JY, Linker SB, Hu L, Schafer ST, Mertens J, Jacinto FV, Hetzer M, Gage FH. 2017. Nup153 interacts with Sox2 to enable bimodal gene regulation and maintenance of neural progenitor cells. Cell Stem Cell. 21(5), 618–634.e7."},"abstract":[{"lang":"eng","text":"Neural progenitor cells (NeuPCs) possess a unique nuclear architecture that changes during differentiation. Nucleoporins are linked with cell-type-specific gene regulation, coupling physical changes in nuclear structure to transcriptional output; but, whether and how they coordinate with key fate-determining transcription factors is unclear. Here we show that the nucleoporin Nup153 interacts with Sox2 in adult NeuPCs, where it is indispensable for their maintenance and controls neuronal differentiation. Genome-wide analyses show that Nup153 and Sox2 bind and co-regulate hundreds of genes. Binding of Nup153 to gene promoters or transcriptional end sites correlates with increased or decreased gene expression, respectively, and inhibiting Nup153 expression alters open chromatin configurations at its target genes, disrupts genomic localization of Sox2, and promotes differentiation in vitro and a gliogenic fate switch in vivo. Together, these findings reveal that nuclear structural proteins may exert bimodal transcriptional effects to control cell fate."}],"publication_status":"published","_id":"11067","oa":1,"pmid":1,"title":"Nup153 interacts with Sox2 to enable bimodal gene regulation and maintenance of neural progenitor cells","publication":"Cell Stem Cell"},{"publication_identifier":{"issn":["01664328"]},"page":"47 - 55","date_published":"2017-04-14T00:00:00Z","file":[{"file_size":2291511,"creator":"system","content_type":"application/pdf","relation":"main_file","date_created":"2018-12-12T10:12:03Z","file_name":"IST-2017-868-v1+1_1-s2.0-S0166432816309160-main.pdf","access_level":"open_access","date_updated":"2018-12-12T10:12:03Z","file_id":"4921"}],"external_id":{"isi":["000397369100007"]},"acknowledgement":"Austrian Science Fund (FWF) for funding this research [I914,P21092]","language":[{"iso":"eng"}],"doi":"10.1016/j.bbr.2017.01.029","has_accepted_license":"1","day":"14","type":"journal_article","date_updated":"2023-09-20T11:37:25Z","oa_version":"Published Version","article_processing_charge":"No","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","status":"public","date_created":"2018-12-11T11:50:11Z","month":"04","publist_id":"6262","isi":1,"intvolume":"       323","publisher":"Elsevier","file_date_updated":"2018-12-12T10:12:03Z","volume":323,"pubrep_id":"868","publication_status":"published","abstract":[{"text":"The generation, migration, and differentiation of neurons requires the functional integrity of the microtubule cytoskeleton. Mutations in the tubulin gene family are known to cause various neurological diseases including lissencephaly, ocular motor disorders, polymicrogyria and amyotrophic lateral sclerosis. We have previously reported that mutations in TUBB5 cause microcephaly that is accompanied by severe intellectual impairment and motor delay. Here we present the characterization of a Tubb5 mouse model that allows for the conditional expression of the pathogenic E401K mutation. Homozygous knockin animals exhibit a severe reduction in brain size and in body weight. These animals do not show any significant impairment in general activity, anxiety, or in the acoustic startle response, however, present with notable defects in motor coordination. When assessed on the static rod apparatus mice took longer to orient and often lost their balance completely. Interestingly, mutant animals also showed defects in prepulse inhibition, a phenotype associated with sensorimotor gating and considered an endophenotype for schizophrenia. This study provides insight into the behavioral consequences of tubulin gene mutations.","lang":"eng"}],"ddc":["570","571"],"oa":1,"_id":"1107","publication":"Behavioural Brain Research","title":"Brain specific knockin of the pathogenic Tubb5 E401K allele causes defects in motor coordination and prepulse inhibition","year":"2017","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png"},"quality_controlled":"1","extern":"1","author":[{"last_name":"Breuss","first_name":"Martin","full_name":"Breuss, Martin"},{"last_name":"Hansen","first_name":"Andi H","full_name":"Hansen, Andi H","id":"38853E16-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Landler, Lukas","last_name":"Landler","first_name":"Lukas"},{"full_name":"Keays, David","first_name":"David","last_name":"Keays"}],"citation":{"mla":"Breuss, Martin, et al. “Brain Specific Knockin of the Pathogenic Tubb5 E401K Allele Causes Defects in Motor Coordination and Prepulse Inhibition.” <i>Behavioural Brain Research</i>, vol. 323, Elsevier, 2017, pp. 47–55, doi:<a href=\"https://doi.org/10.1016/j.bbr.2017.01.029\">10.1016/j.bbr.2017.01.029</a>.","apa":"Breuss, M., Hansen, A. H., Landler, L., &#38; Keays, D. (2017). Brain specific knockin of the pathogenic Tubb5 E401K allele causes defects in motor coordination and prepulse inhibition. <i>Behavioural Brain Research</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.bbr.2017.01.029\">https://doi.org/10.1016/j.bbr.2017.01.029</a>","ista":"Breuss M, Hansen AH, Landler L, Keays D. 2017. Brain specific knockin of the pathogenic Tubb5 E401K allele causes defects in motor coordination and prepulse inhibition. Behavioural Brain Research. 323, 47–55.","chicago":"Breuss, Martin, Andi H Hansen, Lukas Landler, and David Keays. “Brain Specific Knockin of the Pathogenic Tubb5 E401K Allele Causes Defects in Motor Coordination and Prepulse Inhibition.” <i>Behavioural Brain Research</i>. Elsevier, 2017. <a href=\"https://doi.org/10.1016/j.bbr.2017.01.029\">https://doi.org/10.1016/j.bbr.2017.01.029</a>.","short":"M. Breuss, A.H. Hansen, L. Landler, D. Keays, Behavioural Brain Research 323 (2017) 47–55.","ama":"Breuss M, Hansen AH, Landler L, Keays D. Brain specific knockin of the pathogenic Tubb5 E401K allele causes defects in motor coordination and prepulse inhibition. <i>Behavioural Brain Research</i>. 2017;323:47-55. doi:<a href=\"https://doi.org/10.1016/j.bbr.2017.01.029\">10.1016/j.bbr.2017.01.029</a>","ieee":"M. Breuss, A. H. Hansen, L. Landler, and D. Keays, “Brain specific knockin of the pathogenic Tubb5 E401K allele causes defects in motor coordination and prepulse inhibition,” <i>Behavioural Brain Research</i>, vol. 323. Elsevier, pp. 47–55, 2017."}},{"quality_controlled":"1","author":[{"first_name":"Alexander","last_name":"Zimin","full_name":"Zimin, Alexander","id":"37099E9C-F248-11E8-B48F-1D18A9856A87"},{"orcid":"0000-0001-8622-7887","full_name":"Lampert, Christoph","id":"40C20FD2-F248-11E8-B48F-1D18A9856A87","last_name":"Lampert","first_name":"Christoph"}],"main_file_link":[{"url":"http://proceedings.mlr.press/v54/zimin17a/zimin17a.pdf","open_access":"1"}],"citation":{"apa":"Zimin, A., &#38; Lampert, C. (2017). Learning theory for conditional risk minimization (Vol. 54, pp. 213–222). Presented at the AISTATS: Artificial Intelligence and Statistics, Fort Lauderdale, FL, United States: ML Research Press.","mla":"Zimin, Alexander, and Christoph Lampert. <i>Learning Theory for Conditional Risk Minimization</i>. Vol. 54, ML Research Press, 2017, pp. 213–22.","ieee":"A. Zimin and C. Lampert, “Learning theory for conditional risk minimization,” presented at the AISTATS: Artificial Intelligence and Statistics, Fort Lauderdale, FL, United States, 2017, vol. 54, pp. 213–222.","ama":"Zimin A, Lampert C. Learning theory for conditional risk minimization. In: Vol 54. ML Research Press; 2017:213-222.","ista":"Zimin A, Lampert C. 2017. Learning theory for conditional risk minimization. AISTATS: Artificial Intelligence and Statistics, PMLR, vol. 54, 213–222.","chicago":"Zimin, Alexander, and Christoph Lampert. “Learning Theory for Conditional Risk Minimization,” 54:213–22. ML Research Press, 2017.","short":"A. Zimin, C. Lampert, in:, ML Research Press, 2017, pp. 213–222."},"year":"2017","_id":"1108","oa":1,"title":"Learning theory for conditional risk minimization","abstract":[{"lang":"eng","text":"In this work we study the learnability of stochastic processes with respect to the conditional risk, i.e. the existence of a learning algorithm that improves its next-step performance with the amount of observed data. We introduce a notion of pairwise discrepancy between conditional distributions at different times steps and show how certain properties of these discrepancies can be used to construct a successful learning algorithm. Our main results are two theorems that establish criteria for learnability for many classes of stochastic processes, including all special cases studied previously in the literature."}],"publication_status":"published","project":[{"grant_number":"308036","name":"Lifelong Learning of Visual Scene Understanding","call_identifier":"FP7","_id":"2532554C-B435-11E9-9278-68D0E5697425"}],"volume":54,"publisher":"ML Research Press","isi":1,"publist_id":"6261","intvolume":"        54","status":"public","conference":{"start_date":"2017-04-20","location":"Fort Lauderdale, FL, United States","end_date":"2017-04-22","name":"AISTATS: Artificial Intelligence and Statistics"},"month":"04","date_created":"2018-12-11T11:50:11Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_processing_charge":"No","day":"01","oa_version":"Submitted Version","date_updated":"2023-10-17T10:01:12Z","type":"conference","department":[{"_id":"ChLa"}],"language":[{"iso":"eng"}],"ec_funded":1,"page":"213 - 222","external_id":{"isi":["000509368500024"]},"date_published":"2017-04-01T00:00:00Z","alternative_title":["PMLR"]},{"article_processing_charge":"No","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","day":"19","type":"journal_article","date_updated":"2023-09-20T11:36:17Z","oa_version":"Preprint","doi":"10.1103/PhysRevLett.118.203203","language":[{"iso":"eng"}],"department":[{"_id":"MiLe"}],"date_published":"2017-05-19T00:00:00Z","external_id":{"isi":["000401664000005"]},"scopus_import":"1","author":[{"full_name":"Shepperson, Benjamin","first_name":"Benjamin","last_name":"Shepperson"},{"full_name":"Søndergaard, Anders","last_name":"Søndergaard","first_name":"Anders"},{"full_name":"Christiansen, Lars","first_name":"Lars","last_name":"Christiansen"},{"first_name":"Jan","last_name":"Kaczmarczyk","id":"46C405DE-F248-11E8-B48F-1D18A9856A87","full_name":"Kaczmarczyk, Jan","orcid":"0000-0002-1629-3675"},{"first_name":"Robert","last_name":"Zillich","full_name":"Zillich, Robert"},{"full_name":"Lemeshko, Mikhail","orcid":"0000-0002-6990-7802","id":"37CB05FA-F248-11E8-B48F-1D18A9856A87","last_name":"Lemeshko","first_name":"Mikhail"},{"first_name":"Henrik","last_name":"Stapelfeldt","full_name":"Stapelfeldt, Henrik"}],"quality_controlled":"1","main_file_link":[{"url":"https://arxiv.org/abs/1702.01977","open_access":"1"}],"citation":{"ista":"Shepperson B, Søndergaard A, Christiansen L, Kaczmarczyk J, Zillich R, Lemeshko M, Stapelfeldt H. 2017. Laser-induced rotation of iodine molecules in helium nanodroplets: Revivals and breaking-free. Physical Review Letters. 118(20), 203203.","chicago":"Shepperson, Benjamin, Anders Søndergaard, Lars Christiansen, Jan Kaczmarczyk, Robert Zillich, Mikhail Lemeshko, and Henrik Stapelfeldt. “Laser-Induced Rotation of Iodine Molecules in Helium Nanodroplets: Revivals and Breaking-Free.” <i>Physical Review Letters</i>. American Physical Society, 2017. <a href=\"https://doi.org/10.1103/PhysRevLett.118.203203\">https://doi.org/10.1103/PhysRevLett.118.203203</a>.","short":"B. Shepperson, A. Søndergaard, L. Christiansen, J. Kaczmarczyk, R. Zillich, M. Lemeshko, H. Stapelfeldt, Physical Review Letters 118 (2017).","ieee":"B. Shepperson <i>et al.</i>, “Laser-induced rotation of iodine molecules in helium nanodroplets: Revivals and breaking-free,” <i>Physical Review Letters</i>, vol. 118, no. 20. American Physical Society, 2017.","ama":"Shepperson B, Søndergaard A, Christiansen L, et al. Laser-induced rotation of iodine molecules in helium nanodroplets: Revivals and breaking-free. <i>Physical Review Letters</i>. 2017;118(20). doi:<a href=\"https://doi.org/10.1103/PhysRevLett.118.203203\">10.1103/PhysRevLett.118.203203</a>","mla":"Shepperson, Benjamin, et al. “Laser-Induced Rotation of Iodine Molecules in Helium Nanodroplets: Revivals and Breaking-Free.” <i>Physical Review Letters</i>, vol. 118, no. 20, 203203, American Physical Society, 2017, doi:<a href=\"https://doi.org/10.1103/PhysRevLett.118.203203\">10.1103/PhysRevLett.118.203203</a>.","apa":"Shepperson, B., Søndergaard, A., Christiansen, L., Kaczmarczyk, J., Zillich, R., Lemeshko, M., &#38; Stapelfeldt, H. (2017). Laser-induced rotation of iodine molecules in helium nanodroplets: Revivals and breaking-free. <i>Physical Review Letters</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevLett.118.203203\">https://doi.org/10.1103/PhysRevLett.118.203203</a>"},"year":"2017","oa":1,"_id":"1109","publication":"Physical Review Letters","title":"Laser-induced rotation of iodine molecules in helium nanodroplets: Revivals and breaking-free","publication_status":"published","abstract":[{"text":"Rotation of molecules embedded in He nanodroplets is explored by a combination of fs laser-induced alignment experiments and angulon quasiparticle theory. We demonstrate that at low fluence of the fs alignment pulse, the molecule and its solvation shell can be set into coherent collective rotation lasting long enough to form revivals. With increasing fluence, however, the revivals disappear -- instead, rotational dynamics as rapid as for an isolated molecule is observed during the first few picoseconds. Classical calculations trace this phenomenon to transient decoupling of the molecule from its He shell. Our results open novel opportunities for studying non-equilibrium solute-solvent dynamics and quantum thermalization. ","lang":"eng"}],"project":[{"_id":"26031614-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","grant_number":"P29902","name":"Quantum rotations in the presence of a many-body environment"}],"issue":"20","volume":118,"publisher":"American Physical Society","publist_id":"6260","isi":1,"intvolume":"       118","status":"public","article_number":"203203","date_created":"2018-12-11T11:50:12Z","month":"05"},{"title":"Flavonol-induced changes in PIN2 polarity and auxin transport in the Arabidopsis thaliana rol1-2 mutant require phosphatase activity","publication":"Scientific Reports","ddc":["581"],"oa":1,"_id":"1110","project":[{"grant_number":"282300","name":"Polarity and subcellular dynamics in plants","call_identifier":"FP7","_id":"25716A02-B435-11E9-9278-68D0E5697425"}],"publication_status":"published","abstract":[{"text":"The phytohormone auxin is a major determinant and regulatory component important for plant development. Auxin transport between cells is mediated by a complex system of transporters such as AUX1/LAX, PIN, and ABCB proteins, and their localization and activity is thought to be influenced by phosphatases and kinases. Flavonols have been shown to alter auxin transport activity and changes in flavonol accumulation in the Arabidopsis thaliana rol1-2 mutant cause defects in auxin transport and seedling development. A new mutation in ROOTS CURL IN NPA 1 (RCN1), encoding a regulatory subunit of the phosphatase PP2A, was found to suppress the growth defects of rol1-2 without changing the flavonol content. rol1-2 rcn1-3 double mutants show wild type-like auxin transport activity while levels of free auxin are not affected by rcn1-3. In the rol1-2 mutant, PIN2 shows a flavonol-induced basal-to-apical shift in polar localization which is reversed in the rol1-2 rcn1-3 to basal localization. In vivo analysis of PINOID action, a kinase known to influence PIN protein localization in a PP2A-antagonistic manner, revealed a negative impact of flavonols on PINOID activity. Together, these data suggest that flavonols affect auxin transport by modifying the antagonistic kinase/phosphatase equilibrium.","lang":"eng"}],"citation":{"mla":"Kuhn, Benjamin, et al. “Flavonol-Induced Changes in PIN2 Polarity and Auxin Transport in the Arabidopsis Thaliana Rol1-2 Mutant Require Phosphatase Activity.” <i>Scientific Reports</i>, vol. 7, 41906, Nature Publishing Group, 2017, doi:<a href=\"https://doi.org/10.1038/srep41906\">10.1038/srep41906</a>.","apa":"Kuhn, B., Nodzyński, T., Errafi, S., Bucher, R., Gupta, S., Aryal, B., … Ringli, C. (2017). Flavonol-induced changes in PIN2 polarity and auxin transport in the Arabidopsis thaliana rol1-2 mutant require phosphatase activity. <i>Scientific Reports</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/srep41906\">https://doi.org/10.1038/srep41906</a>","ama":"Kuhn B, Nodzyński T, Errafi S, et al. Flavonol-induced changes in PIN2 polarity and auxin transport in the Arabidopsis thaliana rol1-2 mutant require phosphatase activity. <i>Scientific Reports</i>. 2017;7. doi:<a href=\"https://doi.org/10.1038/srep41906\">10.1038/srep41906</a>","ieee":"B. Kuhn <i>et al.</i>, “Flavonol-induced changes in PIN2 polarity and auxin transport in the Arabidopsis thaliana rol1-2 mutant require phosphatase activity,” <i>Scientific Reports</i>, vol. 7. Nature Publishing Group, 2017.","ista":"Kuhn B, Nodzyński T, Errafi S, Bucher R, Gupta S, Aryal B, Dobrev P, Bigler L, Geisler M, Zažímalová E, Friml J, Ringli C. 2017. Flavonol-induced changes in PIN2 polarity and auxin transport in the Arabidopsis thaliana rol1-2 mutant require phosphatase activity. Scientific Reports. 7, 41906.","chicago":"Kuhn, Benjamin, Tomasz Nodzyński, Sanae Errafi, Rahel Bucher, Shibu Gupta, Bibek Aryal, Petre Dobrev, et al. “Flavonol-Induced Changes in PIN2 Polarity and Auxin Transport in the Arabidopsis Thaliana Rol1-2 Mutant Require Phosphatase Activity.” <i>Scientific Reports</i>. Nature Publishing Group, 2017. <a href=\"https://doi.org/10.1038/srep41906\">https://doi.org/10.1038/srep41906</a>.","short":"B. Kuhn, T. Nodzyński, S. Errafi, R. Bucher, S. Gupta, B. Aryal, P. Dobrev, L. Bigler, M. Geisler, E. Zažímalová, J. Friml, C. Ringli, Scientific Reports 7 (2017)."},"author":[{"last_name":"Kuhn","first_name":"Benjamin","full_name":"Kuhn, Benjamin"},{"first_name":"Tomasz","last_name":"Nodzyński","full_name":"Nodzyński, Tomasz"},{"last_name":"Errafi","first_name":"Sanae","full_name":"Errafi, Sanae"},{"last_name":"Bucher","first_name":"Rahel","full_name":"Bucher, Rahel"},{"full_name":"Gupta, Shibu","last_name":"Gupta","first_name":"Shibu"},{"full_name":"Aryal, Bibek","first_name":"Bibek","last_name":"Aryal"},{"full_name":"Dobrev, Petre","last_name":"Dobrev","first_name":"Petre"},{"full_name":"Bigler, Laurent","last_name":"Bigler","first_name":"Laurent"},{"full_name":"Geisler, Markus","last_name":"Geisler","first_name":"Markus"},{"full_name":"Zažímalová, Eva","first_name":"Eva","last_name":"Zažímalová"},{"orcid":"0000-0002-8302-7596","full_name":"Friml, Jirí","id":"4159519E-F248-11E8-B48F-1D18A9856A87","first_name":"Jirí","last_name":"Friml"},{"last_name":"Ringli","first_name":"Christoph","full_name":"Ringli, Christoph"}],"quality_controlled":"1","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"year":"2017","intvolume":"         7","publist_id":"6258","isi":1,"date_created":"2018-12-11T11:50:12Z","month":"02","status":"public","article_number":"41906","volume":7,"pubrep_id":"803","file_date_updated":"2018-12-12T10:18:09Z","publisher":"Nature Publishing Group","ec_funded":1,"doi":"10.1038/srep41906","language":[{"iso":"eng"}],"has_accepted_license":"1","department":[{"_id":"JiFr"}],"acknowledgement":"European Research Council (project ERC-2011-StG-20101109-PSDP), European Social Fund (CZ.1.07/2.3.00/20.0043) and the Czech Science Foundation (GA13-40637S) [JF].","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","article_processing_charge":"No","type":"journal_article","date_updated":"2025-05-07T11:12:29Z","oa_version":"Published Version","day":"06","publication_identifier":{"issn":["20452322"]},"scopus_import":"1","date_published":"2017-02-06T00:00:00Z","external_id":{"isi":["000393367600001"]},"file":[{"access_level":"open_access","file_name":"IST-2017-803-v1+1_srep41906.pdf","date_updated":"2018-12-12T10:18:09Z","file_id":"5328","creator":"system","content_type":"application/pdf","file_size":1654496,"date_created":"2018-12-12T10:18:09Z","relation":"main_file"}]},{"date_created":"2018-12-11T11:50:12Z","month":"02","status":"public","intvolume":"       205","publist_id":"6256","isi":1,"publisher":"Genetics Society of America","article_type":"original","issue":"2","volume":205,"project":[{"name":"Speed of Adaptation in Population Genetics and Evolutionary Computation","grant_number":"618091","call_identifier":"FP7","_id":"25B1EC9E-B435-11E9-9278-68D0E5697425"}],"publication_status":"published","abstract":[{"text":"Adaptation depends critically on the effects of new mutations and their dependency on the genetic background in which they occur. These two factors can be summarized by the fitness landscape. However, it would require testing all mutations in all backgrounds, making the definition and analysis of fitness landscapes mostly inaccessible. Instead of postulating a particular fitness landscape, we address this problem by considering general classes of landscapes and calculating an upper limit for the time it takes for a population to reach a fitness peak, circumventing the need to have full knowledge about the fitness landscape. We analyze populations in the weak-mutation regime and characterize the conditions that enable them to quickly reach the fitness peak as a function of the number of sites under selection. We show that for additive landscapes there is a critical selection strength enabling populations to reach high-fitness genotypes, regardless of the distribution of effects. This threshold scales with the number of sites under selection, effectively setting a limit to adaptation, and results from the inevitable increase in deleterious mutational pressure as the population adapts in a space of discrete genotypes. Furthermore, we show that for the class of all unimodal landscapes this condition is sufficient but not necessary for rapid adaptation, as in some highly epistatic landscapes the critical strength does not depend on the number of sites under selection; effectively removing this barrier to adaptation.","lang":"eng"}],"publication":"Genetics","title":"Selection limits to adaptive walks on correlated landscapes","pmid":1,"oa":1,"_id":"1111","year":"2017","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1534/genetics.116.189340"}],"citation":{"ama":"Heredia J, Trubenova B, Sudholt D, Paixao T. Selection limits to adaptive walks on correlated landscapes. <i>Genetics</i>. 2017;205(2):803-825. doi:<a href=\"https://doi.org/10.1534/genetics.116.189340\">10.1534/genetics.116.189340</a>","ieee":"J. Heredia, B. Trubenova, D. Sudholt, and T. Paixao, “Selection limits to adaptive walks on correlated landscapes,” <i>Genetics</i>, vol. 205, no. 2. Genetics Society of America, pp. 803–825, 2017.","ista":"Heredia J, Trubenova B, Sudholt D, Paixao T. 2017. Selection limits to adaptive walks on correlated landscapes. Genetics. 205(2), 803–825.","short":"J. Heredia, B. Trubenova, D. Sudholt, T. Paixao, Genetics 205 (2017) 803–825.","chicago":"Heredia, Jorge, Barbora Trubenova, Dirk Sudholt, and Tiago Paixao. “Selection Limits to Adaptive Walks on Correlated Landscapes.” <i>Genetics</i>. Genetics Society of America, 2017. <a href=\"https://doi.org/10.1534/genetics.116.189340\">https://doi.org/10.1534/genetics.116.189340</a>.","mla":"Heredia, Jorge, et al. “Selection Limits to Adaptive Walks on Correlated Landscapes.” <i>Genetics</i>, vol. 205, no. 2, Genetics Society of America, 2017, pp. 803–25, doi:<a href=\"https://doi.org/10.1534/genetics.116.189340\">10.1534/genetics.116.189340</a>.","apa":"Heredia, J., Trubenova, B., Sudholt, D., &#38; Paixao, T. (2017). Selection limits to adaptive walks on correlated landscapes. <i>Genetics</i>. Genetics Society of America. <a href=\"https://doi.org/10.1534/genetics.116.189340\">https://doi.org/10.1534/genetics.116.189340</a>"},"author":[{"first_name":"Jorge","last_name":"Heredia","full_name":"Heredia, Jorge"},{"full_name":"Trubenova, Barbora","orcid":"0000-0002-6873-2967","id":"42302D54-F248-11E8-B48F-1D18A9856A87","first_name":"Barbora","last_name":"Trubenova"},{"last_name":"Sudholt","first_name":"Dirk","full_name":"Sudholt, Dirk"},{"full_name":"Paixao, Tiago","orcid":"0000-0003-2361-3953","id":"2C5658E6-F248-11E8-B48F-1D18A9856A87","first_name":"Tiago","last_name":"Paixao"}],"quality_controlled":"1","publication_identifier":{"issn":["00166731"]},"scopus_import":"1","date_published":"2017-02-01T00:00:00Z","external_id":{"isi":["000394144900025"],"pmid":["27881471"]},"page":"803 - 825","ec_funded":1,"doi":"10.1534/genetics.116.189340","language":[{"iso":"eng"}],"department":[{"_id":"NiBa"}],"date_updated":"2023-09-20T11:35:03Z","type":"journal_article","oa_version":"Published Version","day":"01","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","article_processing_charge":"No"},{"department":[{"_id":"NiBa"}],"_id":"1112","language":[{"iso":"eng"}],"doi":"10.1145/3040718.3040729","publication":"Proceedings of the 14th ACM/SIGEVO Conference on Foundations of Genetic Algorithms","title":"An application of stochastic differential equations to evolutionary algorithms","abstract":[{"text":"There has been renewed interest in modelling the behaviour of evolutionary algorithms by more traditional mathematical objects, such as ordinary differential equations or Markov chains. The advantage is that the analysis becomes greatly facilitated due to the existence of well established methods. However, this typically comes at the cost of disregarding information about the process. Here, we introduce the use of stochastic differential equations (SDEs) for the study of EAs. SDEs can produce simple analytical results for the dynamics of stochastic processes, unlike Markov chains which can produce rigorous but unwieldy expressions about the dynamics. On the other hand, unlike ordinary differential equations (ODEs), they do not discard information about the stochasticity of the process. We show that these are especially suitable for the analysis of fixed budget scenarios and present analogs of the additive and multiplicative drift theorems for SDEs. We exemplify the use of these methods for two model algorithms ((1+1) EA and RLS) on two canonical problems(OneMax and LeadingOnes).","lang":"eng"}],"publication_status":"published","quality_controlled":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","author":[{"last_name":"Paixao","first_name":"Tiago","id":"2C5658E6-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-2361-3953","full_name":"Paixao, Tiago"},{"full_name":"Pérez Heredia, Jorge","first_name":"Jorge","last_name":"Pérez Heredia"}],"citation":{"chicago":"Paixao, Tiago, and Jorge Pérez Heredia. “An Application of Stochastic Differential Equations to Evolutionary Algorithms.” In <i>Proceedings of the 14th ACM/SIGEVO Conference on Foundations of Genetic Algorithms</i>, 3–11. ACM, 2017. <a href=\"https://doi.org/10.1145/3040718.3040729\">https://doi.org/10.1145/3040718.3040729</a>.","short":"T. Paixao, J. Pérez Heredia, in:, Proceedings of the 14th ACM/SIGEVO Conference on Foundations of Genetic Algorithms, ACM, 2017, pp. 3–11.","ista":"Paixao T, Pérez Heredia J. 2017. An application of stochastic differential equations to evolutionary algorithms. Proceedings of the 14th ACM/SIGEVO Conference on Foundations of Genetic Algorithms. FOGA: Foundations of Genetic Algorithms, 3–11.","ieee":"T. Paixao and J. Pérez Heredia, “An application of stochastic differential equations to evolutionary algorithms,” in <i>Proceedings of the 14th ACM/SIGEVO Conference on Foundations of Genetic Algorithms</i>, Copenhagen, Denmark, 2017, pp. 3–11.","ama":"Paixao T, Pérez Heredia J. An application of stochastic differential equations to evolutionary algorithms. In: <i>Proceedings of the 14th ACM/SIGEVO Conference on Foundations of Genetic Algorithms</i>. ACM; 2017:3-11. doi:<a href=\"https://doi.org/10.1145/3040718.3040729\">10.1145/3040718.3040729</a>","mla":"Paixao, Tiago, and Jorge Pérez Heredia. “An Application of Stochastic Differential Equations to Evolutionary Algorithms.” <i>Proceedings of the 14th ACM/SIGEVO Conference on Foundations of Genetic Algorithms</i>, ACM, 2017, pp. 3–11, doi:<a href=\"https://doi.org/10.1145/3040718.3040729\">10.1145/3040718.3040729</a>.","apa":"Paixao, T., &#38; Pérez Heredia, J. (2017). An application of stochastic differential equations to evolutionary algorithms. In <i>Proceedings of the 14th ACM/SIGEVO Conference on Foundations of Genetic Algorithms</i> (pp. 3–11). Copenhagen, Denmark: ACM. <a href=\"https://doi.org/10.1145/3040718.3040729\">https://doi.org/10.1145/3040718.3040729</a>"},"year":"2017","day":"12","oa_version":"None","type":"conference","date_updated":"2021-01-12T06:48:22Z","scopus_import":1,"publist_id":"6255","publication_identifier":{"isbn":["978-145034651-1"]},"status":"public","conference":{"location":"Copenhagen, Denmark","start_date":"2017-01-12","end_date":"2017-01-15","name":"FOGA: Foundations of Genetic Algorithms"},"month":"01","date_created":"2018-12-11T11:50:12Z","page":"3 - 11","date_published":"2017-01-12T00:00:00Z","publisher":"ACM"}]