[{"page":"1672 - 1705","year":"2017","date_published":"2017-09-01T00:00:00Z","intvolume":"        70","month":"09","date_updated":"2021-01-12T08:12:24Z","oa":1,"issue":"9","publication":"Communications on Pure and Applied Mathematics","doi":"10.1002/cpa.21639","main_file_link":[{"url":"https://arxiv.org/abs/1512.03703","open_access":"1"}],"ec_funded":1,"oa_version":"Submitted Version","volume":70,"date_created":"2018-12-11T11:48:08Z","status":"public","day":"01","department":[{"_id":"LaEr"}],"publist_id":"6959","language":[{"iso":"eng"}],"publisher":"Wiley-Blackwell","author":[{"first_name":"Oskari H","id":"36F2FB7E-F248-11E8-B48F-1D18A9856A87","last_name":"Ajanki","full_name":"Ajanki, Oskari H"},{"full_name":"Krüger, Torben H","id":"3020C786-F248-11E8-B48F-1D18A9856A87","first_name":"Torben H","orcid":"0000-0002-4821-3297","last_name":"Krüger"},{"first_name":"László","id":"4DBD5372-F248-11E8-B48F-1D18A9856A87","last_name":"Erdös","orcid":"0000-0001-5366-9603","full_name":"Erdös, László"}],"title":"Singularities of solutions to quadratic vector equations on the complex upper half plane","user_id":"4435EBFC-F248-11E8-B48F-1D18A9856A87","project":[{"name":"Random matrices, universality and disordered quantum systems","_id":"258DCDE6-B435-11E9-9278-68D0E5697425","grant_number":"338804","call_identifier":"FP7"}],"publication_status":"published","citation":{"apa":"Ajanki, O. H., Krüger, T. H., &#38; Erdös, L. (2017). Singularities of solutions to quadratic vector equations on the complex upper half plane. <i>Communications on Pure and Applied Mathematics</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1002/cpa.21639\">https://doi.org/10.1002/cpa.21639</a>","mla":"Ajanki, Oskari H., et al. “Singularities of Solutions to Quadratic Vector Equations on the Complex Upper Half Plane.” <i>Communications on Pure and Applied Mathematics</i>, vol. 70, no. 9, Wiley-Blackwell, 2017, pp. 1672–705, doi:<a href=\"https://doi.org/10.1002/cpa.21639\">10.1002/cpa.21639</a>.","ama":"Ajanki OH, Krüger TH, Erdös L. Singularities of solutions to quadratic vector equations on the complex upper half plane. <i>Communications on Pure and Applied Mathematics</i>. 2017;70(9):1672-1705. doi:<a href=\"https://doi.org/10.1002/cpa.21639\">10.1002/cpa.21639</a>","short":"O.H. Ajanki, T.H. Krüger, L. Erdös, Communications on Pure and Applied Mathematics 70 (2017) 1672–1705.","ieee":"O. H. Ajanki, T. H. Krüger, and L. Erdös, “Singularities of solutions to quadratic vector equations on the complex upper half plane,” <i>Communications on Pure and Applied Mathematics</i>, vol. 70, no. 9. Wiley-Blackwell, pp. 1672–1705, 2017.","ista":"Ajanki OH, Krüger TH, Erdös L. 2017. Singularities of solutions to quadratic vector equations on the complex upper half plane. Communications on Pure and Applied Mathematics. 70(9), 1672–1705.","chicago":"Ajanki, Oskari H, Torben H Krüger, and László Erdös. “Singularities of Solutions to Quadratic Vector Equations on the Complex Upper Half Plane.” <i>Communications on Pure and Applied Mathematics</i>. Wiley-Blackwell, 2017. <a href=\"https://doi.org/10.1002/cpa.21639\">https://doi.org/10.1002/cpa.21639</a>."},"publication_identifier":{"issn":["00103640"]},"abstract":[{"text":"Let S be a positivity-preserving symmetric linear operator acting on bounded functions. The nonlinear equation -1/m=z+Sm with a parameter z in the complex upper half-plane ℍ has a unique solution m with values in ℍ. We show that the z-dependence of this solution can be represented as the Stieltjes transforms of a family of probability measures v on ℝ. Under suitable conditions on S, we show that v has a real analytic density apart from finitely many algebraic singularities of degree at most 3. Our motivation comes from large random matrices. The solution m determines the density of eigenvalues of two prominent matrix ensembles: (i) matrices with centered independent entries whose variances are given by S and (ii) matrices with correlated entries with a translation-invariant correlation structure. Our analysis shows that the limiting eigenvalue density has only square root singularities or cubic root cusps; no other singularities occur.","lang":"eng"}],"scopus_import":1,"type":"journal_article","_id":"721","quality_controlled":"1"},{"doi":"10.1016/j.cub.2017.06.043","publication":"Current Biology","ec_funded":1,"oa_version":"Submitted Version","pmid":1,"volume":27,"day":"11","status":"public","tmp":{"short":"CC BY-NC-ND (4.0)","image":"/images/cc_by_nc_nd.png","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)"},"date_created":"2018-12-11T11:48:08Z","ddc":["581"],"external_id":{"pmid":["28898665"]},"page":"R919 - R930","year":"2017","month":"09","intvolume":"        27","date_published":"2017-09-11T00:00:00Z","issue":"17","oa":1,"date_updated":"2021-01-12T08:12:29Z","publication_status":"published","project":[{"_id":"25681D80-B435-11E9-9278-68D0E5697425","name":"International IST Postdoc Fellowship Programme","call_identifier":"FP7","grant_number":"291734"}],"type":"journal_article","file_date_updated":"2020-07-14T12:47:54Z","scopus_import":1,"abstract":[{"lang":"eng","text":"Plants are sessile organisms rooted in one place. The soil resources that plants require are often distributed in a highly heterogeneous pattern. To aid foraging, plants have evolved roots whose growth and development are highly responsive to soil signals. As a result, 3D root architecture is shaped by myriad environmental signals to ensure resource capture is optimised and unfavourable environments are avoided. The first signals sensed by newly germinating seeds — gravity and light — direct root growth into the soil to aid seedling establishment. Heterogeneous soil resources, such as water, nitrogen and phosphate, also act as signals that shape 3D root growth to optimise uptake. Root architecture is also modified through biotic interactions that include soil fungi and neighbouring plants. This developmental plasticity results in a ‘custom-made’ 3D root system that is best adapted to forage for resources in each soil environment that a plant colonises."}],"citation":{"ama":"Morris E, Griffiths M, Golebiowska A, et al. Shaping 3D root system architecture. <i>Current Biology</i>. 2017;27(17):R919-R930. doi:<a href=\"https://doi.org/10.1016/j.cub.2017.06.043\">10.1016/j.cub.2017.06.043</a>","ieee":"E. Morris <i>et al.</i>, “Shaping 3D root system architecture,” <i>Current Biology</i>, vol. 27, no. 17. Cell Press, pp. R919–R930, 2017.","short":"E. Morris, M. Griffiths, A. Golebiowska, S. Mairhofer, J. Burr Hersey, T. Goh, D. von Wangenheim, B. Atkinson, C. Sturrock, J. Lynch, K. Vissenberg, K. Ritz, D. Wells, S. Mooney, M. Bennett, Current Biology 27 (2017) R919–R930.","ista":"Morris E, Griffiths M, Golebiowska A, Mairhofer S, Burr Hersey J, Goh T, von Wangenheim D, Atkinson B, Sturrock C, Lynch J, Vissenberg K, Ritz K, Wells D, Mooney S, Bennett M. 2017. Shaping 3D root system architecture. Current Biology. 27(17), R919–R930.","chicago":"Morris, Emily, Marcus Griffiths, Agata Golebiowska, Stefan Mairhofer, Jasmine Burr Hersey, Tatsuaki Goh, Daniel von Wangenheim, et al. “Shaping 3D Root System Architecture.” <i>Current Biology</i>. Cell Press, 2017. <a href=\"https://doi.org/10.1016/j.cub.2017.06.043\">https://doi.org/10.1016/j.cub.2017.06.043</a>.","apa":"Morris, E., Griffiths, M., Golebiowska, A., Mairhofer, S., Burr Hersey, J., Goh, T., … Bennett, M. (2017). Shaping 3D root system architecture. <i>Current Biology</i>. Cell Press. <a href=\"https://doi.org/10.1016/j.cub.2017.06.043\">https://doi.org/10.1016/j.cub.2017.06.043</a>","mla":"Morris, Emily, et al. “Shaping 3D Root System Architecture.” <i>Current Biology</i>, vol. 27, no. 17, Cell Press, 2017, pp. R919–30, doi:<a href=\"https://doi.org/10.1016/j.cub.2017.06.043\">10.1016/j.cub.2017.06.043</a>."},"publication_identifier":{"issn":["09609822"]},"quality_controlled":"1","_id":"722","department":[{"_id":"JiFr"}],"publist_id":"6956","pubrep_id":"982","language":[{"iso":"eng"}],"publisher":"Cell Press","has_accepted_license":"1","file":[{"date_updated":"2020-07-14T12:47:54Z","date_created":"2019-04-17T07:46:40Z","file_name":"2017_CurrentBiology_Morris.pdf","checksum":"e45588b21097b408da6276a3e5eedb2e","access_level":"open_access","relation":"main_file","creator":"dernst","file_size":1576593,"content_type":"application/pdf","file_id":"6332"}],"title":"Shaping 3D root system architecture","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","author":[{"full_name":"Morris, Emily","last_name":"Morris","first_name":"Emily"},{"full_name":"Griffiths, Marcus","last_name":"Griffiths","first_name":"Marcus"},{"first_name":"Agata","last_name":"Golebiowska","full_name":"Golebiowska, Agata"},{"first_name":"Stefan","last_name":"Mairhofer","full_name":"Mairhofer, Stefan"},{"full_name":"Burr Hersey, Jasmine","last_name":"Burr Hersey","first_name":"Jasmine"},{"first_name":"Tatsuaki","last_name":"Goh","full_name":"Goh, Tatsuaki"},{"last_name":"Von Wangenheim","orcid":"0000-0002-6862-1247","first_name":"Daniel","id":"49E91952-F248-11E8-B48F-1D18A9856A87","full_name":"Von Wangenheim, Daniel"},{"last_name":"Atkinson","first_name":"Brian","full_name":"Atkinson, Brian"},{"first_name":"Craig","last_name":"Sturrock","full_name":"Sturrock, Craig"},{"last_name":"Lynch","first_name":"Jonathan","full_name":"Lynch, Jonathan"},{"first_name":"Kris","last_name":"Vissenberg","full_name":"Vissenberg, Kris"},{"full_name":"Ritz, Karl","last_name":"Ritz","first_name":"Karl"},{"full_name":"Wells, Darren","last_name":"Wells","first_name":"Darren"},{"full_name":"Mooney, Sacha","last_name":"Mooney","first_name":"Sacha"},{"first_name":"Malcolm","last_name":"Bennett","full_name":"Bennett, Malcolm"}]},{"acknowledgement":"We  would  like  to  thank  Dmitry  Abanin,  Christophe  De\r\nBeule,  Joel  Moore,  Romain  Vasseur,  and  Norman  Yao  for\r\nmany  stimulating  discussions.  Financial  support  has  been\r\nprovided  by  the  Deutsche  Forschungsgemeinschaft  (DFG)\r\nvia Grant No. TR950/8-1, SFB 1170 “ToCoTronics” and the\r\nENB  Graduate  School  on  Topological  Insulators.  M.S.  was\r\nsupported by Gordon and Betty Moore Foundation’s EPiQS\r\nInitiative through Grant No. GBMF4307. F.P. acknowledges\r\nsupport from the DFG Research Unit FOR 1807 through Grant\r\nNo. PO 1370/2-1.","article_number":"104203","intvolume":"        96","month":"09","date_published":"2017-09-13T00:00:00Z","issue":"10","oa":1,"date_updated":"2021-01-12T08:12:35Z","year":"2017","volume":96,"status":"public","day":"13","date_created":"2018-12-11T11:48:09Z","doi":"10.1103/PhysRevB.96.104203","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1701.02744"}],"publication":"Physical Review B","oa_version":"Submitted Version","publisher":"American Physical Society","author":[{"first_name":"Daniel","last_name":"Hetterich","full_name":"Hetterich, Daniel"},{"id":"47809E7E-F248-11E8-B48F-1D18A9856A87","first_name":"Maksym","last_name":"Serbyn","orcid":"0000-0002-2399-5827","full_name":"Serbyn, Maksym"},{"full_name":"Domínguez, Fernando","first_name":"Fernando","last_name":"Domínguez"},{"first_name":"Frank","last_name":"Pollmann","full_name":"Pollmann, Frank"},{"full_name":"Trauzettel, Björn","first_name":"Björn","last_name":"Trauzettel"}],"title":"Noninteracting central site model localization and logarithmic entanglement growth","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publist_id":"6955","department":[{"_id":"MaSe"}],"language":[{"iso":"eng"}],"type":"journal_article","scopus_import":1,"abstract":[{"lang":"eng","text":"We investigate the stationary and dynamical behavior of an Anderson localized chain coupled to a single central bound state. Although this coupling partially dilutes the Anderson localized peaks towards nearly resonant sites, the most weight of the original peaks remains unchanged. This leads to multifractal wave functions with a frozen spectrum of fractal dimensions, which is characteristic for localized phases in models with power-law hopping. Using a perturbative approach we identify two different dynamical regimes. At weak couplings to the central site, the transport of particles and information is logarithmic in time, a feature usually attributed to many-body localization. We connect such transport to the persistence of the Poisson statistics of level spacings in parts of the spectrum. In contrast, at stronger couplings the level repulsion is established in the entire spectrum, the problem can be mapped to the Fano resonance, and the transport is ballistic."}],"citation":{"mla":"Hetterich, Daniel, et al. “Noninteracting Central Site Model Localization and Logarithmic Entanglement Growth.” <i>Physical Review B</i>, vol. 96, no. 10, 104203, American Physical Society, 2017, doi:<a href=\"https://doi.org/10.1103/PhysRevB.96.104203\">10.1103/PhysRevB.96.104203</a>.","apa":"Hetterich, D., Serbyn, M., Domínguez, F., Pollmann, F., &#38; Trauzettel, B. (2017). Noninteracting central site model localization and logarithmic entanglement growth. <i>Physical Review B</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevB.96.104203\">https://doi.org/10.1103/PhysRevB.96.104203</a>","chicago":"Hetterich, Daniel, Maksym Serbyn, Fernando Domínguez, Frank Pollmann, and Björn Trauzettel. “Noninteracting Central Site Model Localization and Logarithmic Entanglement Growth.” <i>Physical Review B</i>. American Physical Society, 2017. <a href=\"https://doi.org/10.1103/PhysRevB.96.104203\">https://doi.org/10.1103/PhysRevB.96.104203</a>.","ista":"Hetterich D, Serbyn M, Domínguez F, Pollmann F, Trauzettel B. 2017. Noninteracting central site model localization and logarithmic entanglement growth. Physical Review B. 96(10), 104203.","short":"D. Hetterich, M. Serbyn, F. Domínguez, F. Pollmann, B. Trauzettel, Physical Review B 96 (2017).","ieee":"D. Hetterich, M. Serbyn, F. Domínguez, F. Pollmann, and B. Trauzettel, “Noninteracting central site model localization and logarithmic entanglement growth,” <i>Physical Review B</i>, vol. 96, no. 10. American Physical Society, 2017.","ama":"Hetterich D, Serbyn M, Domínguez F, Pollmann F, Trauzettel B. Noninteracting central site model localization and logarithmic entanglement growth. <i>Physical Review B</i>. 2017;96(10). doi:<a href=\"https://doi.org/10.1103/PhysRevB.96.104203\">10.1103/PhysRevB.96.104203</a>"},"publication_identifier":{"issn":["24699950"]},"quality_controlled":"1","_id":"724","publication_status":"published"},{"day":"19","status":"public","date_created":"2018-12-11T11:48:10Z","pmid":1,"volume":114,"oa_version":"Submitted Version","main_file_link":[{"open_access":"1","url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617265/"}],"doi":"10.1073/pnas.1703817114","publication":"PNAS","issue":"38","oa":1,"date_updated":"2021-01-12T08:12:36Z","intvolume":"       114","month":"09","date_published":"2017-09-19T00:00:00Z","year":"2017","external_id":{"pmid":["28874581"]},"page":"10149 - 10154","quality_controlled":"1","_id":"725","type":"journal_article","scopus_import":1,"abstract":[{"lang":"eng","text":"Individual computations and social interactions underlying collective behavior in groups of animals are of great ethological, behavioral, and theoretical interest. While complex individual behaviors have successfully been parsed into small dictionaries of stereotyped behavioral modes, studies of collective behavior largely ignored these findings; instead, their focus was on inferring single, mode-independent social interaction rules that reproduced macroscopic and often qualitative features of group behavior. Here, we bring these two approaches together to predict individual swimming patterns of adult zebrafish in a group. We show that fish alternate between an “active” mode, in which they are sensitive to the swimming patterns of conspecifics, and a “passive” mode, where they ignore them. Using a model that accounts for these two modes explicitly, we predict behaviors of individual fish with high accuracy, outperforming previous approaches that assumed a single continuous computation by individuals and simple metric or topological weighing of neighbors’ behavior. At the group level, switching between active and passive modes is uncorrelated among fish, but correlated directional swimming behavior still emerges. Our quantitative approach for studying complex, multi-modal individual behavior jointly with emergent group behavior is readily extensible to additional behavioral modes and their neural correlates as well as to other species."}],"citation":{"chicago":"Harpaz, Roy, Gašper Tkačik, and Elad Schneidman. “Discrete Modes of Social Information Processing Predict Individual Behavior of Fish in a Group.” <i>PNAS</i>. National Academy of Sciences, 2017. <a href=\"https://doi.org/10.1073/pnas.1703817114\">https://doi.org/10.1073/pnas.1703817114</a>.","ieee":"R. Harpaz, G. Tkačik, and E. Schneidman, “Discrete modes of social information processing predict individual behavior of fish in a group,” <i>PNAS</i>, vol. 114, no. 38. National Academy of Sciences, pp. 10149–10154, 2017.","short":"R. Harpaz, G. Tkačik, E. Schneidman, PNAS 114 (2017) 10149–10154.","ista":"Harpaz R, Tkačik G, Schneidman E. 2017. Discrete modes of social information processing predict individual behavior of fish in a group. PNAS. 114(38), 10149–10154.","ama":"Harpaz R, Tkačik G, Schneidman E. Discrete modes of social information processing predict individual behavior of fish in a group. <i>PNAS</i>. 2017;114(38):10149-10154. doi:<a href=\"https://doi.org/10.1073/pnas.1703817114\">10.1073/pnas.1703817114</a>","mla":"Harpaz, Roy, et al. “Discrete Modes of Social Information Processing Predict Individual Behavior of Fish in a Group.” <i>PNAS</i>, vol. 114, no. 38, National Academy of Sciences, 2017, pp. 10149–54, doi:<a href=\"https://doi.org/10.1073/pnas.1703817114\">10.1073/pnas.1703817114</a>.","apa":"Harpaz, R., Tkačik, G., &#38; Schneidman, E. (2017). Discrete modes of social information processing predict individual behavior of fish in a group. <i>PNAS</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.1703817114\">https://doi.org/10.1073/pnas.1703817114</a>"},"publication_identifier":{"issn":["00278424"]},"publication_status":"published","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","author":[{"last_name":"Harpaz","first_name":"Roy","full_name":"Harpaz, Roy"},{"full_name":"Tkacik, Gasper","first_name":"Gasper","id":"3D494DCA-F248-11E8-B48F-1D18A9856A87","last_name":"Tkacik","orcid":"0000-0002-6699-1455"},{"first_name":"Elad","last_name":"Schneidman","full_name":"Schneidman, Elad"}],"title":"Discrete modes of social information processing predict individual behavior of fish in a group","publisher":"National Academy of Sciences","language":[{"iso":"eng"}],"department":[{"_id":"GaTk"}],"publist_id":"6953"},{"year":"2017","external_id":{"isi":["000411331800024"]},"page":"242 - 255","date_updated":"2023-09-28T11:34:17Z","oa":1,"issue":"1","date_published":"2017-09-21T00:00:00Z","month":"09","intvolume":"       171","oa_version":"Published Version","isi":1,"publication":"Cell","doi":"10.1016/j.cell.2017.08.026","date_created":"2018-12-11T11:48:10Z","tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"ddc":["539"],"status":"public","day":"21","volume":171,"language":[{"iso":"eng"}],"pubrep_id":"883","article_processing_charge":"No","publist_id":"6952","department":[{"_id":"EdHa"}],"title":"A unifying theory of branching morphogenesis","author":[{"orcid":"0000-0001-6005-1561","last_name":"Hannezo","first_name":"Edouard B","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","full_name":"Hannezo, Edouard B"},{"last_name":"Scheele","first_name":"Colinda","full_name":"Scheele, Colinda"},{"full_name":"Moad, Mohammad","first_name":"Mohammad","last_name":"Moad"},{"full_name":"Drogo, Nicholas","first_name":"Nicholas","last_name":"Drogo"},{"first_name":"Rakesh","last_name":"Heer","full_name":"Heer, Rakesh"},{"full_name":"Sampogna, Rosemary","last_name":"Sampogna","first_name":"Rosemary"},{"full_name":"Van Rheenen, Jacco","first_name":"Jacco","last_name":"Van Rheenen"},{"last_name":"Simons","first_name":"Benjamin","full_name":"Simons, Benjamin"}],"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","file":[{"relation":"main_file","access_level":"open_access","checksum":"7a036d93a9e2e597af9bb504d6133aca","file_id":"4870","content_type":"application/pdf","file_size":12670204,"creator":"system","date_created":"2018-12-12T10:11:17Z","date_updated":"2020-07-14T12:47:55Z","file_name":"IST-2017-883-v1+1_PIIS0092867417309510.pdf"}],"has_accepted_license":"1","publisher":"Cell Press","publication_status":"published","_id":"726","quality_controlled":"1","citation":{"apa":"Hannezo, E. B., Scheele, C., Moad, M., Drogo, N., Heer, R., Sampogna, R., … Simons, B. (2017). A unifying theory of branching morphogenesis. <i>Cell</i>. Cell Press. <a href=\"https://doi.org/10.1016/j.cell.2017.08.026\">https://doi.org/10.1016/j.cell.2017.08.026</a>","mla":"Hannezo, Edouard B., et al. “A Unifying Theory of Branching Morphogenesis.” <i>Cell</i>, vol. 171, no. 1, Cell Press, 2017, pp. 242–55, doi:<a href=\"https://doi.org/10.1016/j.cell.2017.08.026\">10.1016/j.cell.2017.08.026</a>.","ieee":"E. B. Hannezo <i>et al.</i>, “A unifying theory of branching morphogenesis,” <i>Cell</i>, vol. 171, no. 1. Cell Press, pp. 242–255, 2017.","short":"E.B. Hannezo, C. Scheele, M. Moad, N. Drogo, R. Heer, R. Sampogna, J. Van Rheenen, B. Simons, Cell 171 (2017) 242–255.","ista":"Hannezo EB, Scheele C, Moad M, Drogo N, Heer R, Sampogna R, Van Rheenen J, Simons B. 2017. A unifying theory of branching morphogenesis. Cell. 171(1), 242–255.","ama":"Hannezo EB, Scheele C, Moad M, et al. A unifying theory of branching morphogenesis. <i>Cell</i>. 2017;171(1):242-255. doi:<a href=\"https://doi.org/10.1016/j.cell.2017.08.026\">10.1016/j.cell.2017.08.026</a>","chicago":"Hannezo, Edouard B, Colinda Scheele, Mohammad Moad, Nicholas Drogo, Rakesh Heer, Rosemary Sampogna, Jacco Van Rheenen, and Benjamin Simons. “A Unifying Theory of Branching Morphogenesis.” <i>Cell</i>. Cell Press, 2017. <a href=\"https://doi.org/10.1016/j.cell.2017.08.026\">https://doi.org/10.1016/j.cell.2017.08.026</a>."},"publication_identifier":{"issn":["00928674"]},"abstract":[{"text":"The morphogenesis of branched organs remains a subject of abiding interest. Although much is known about the underlying signaling pathways, it remains unclear how macroscopic features of branched organs, including their size, network topology, and spatial patterning, are encoded. Here, we show that, in mouse mammary gland, kidney, and human prostate, these features can be explained quantitatively within a single unifying framework of branching and annihilating random walks. Based on quantitative analyses of large-scale organ reconstructions and proliferation kinetics measurements, we propose that morphogenesis follows from the proliferative activity of equipotent tips that stochastically branch and randomly explore their environment but compete neutrally for space, becoming proliferatively inactive when in proximity with neighboring ducts. These results show that complex branched epithelial structures develop as a self-organized process, reliant upon a strikingly simple but generic rule, without recourse to a rigid and deterministic sequence of genetically programmed events.","lang":"eng"}],"scopus_import":"1","type":"journal_article","file_date_updated":"2020-07-14T12:47:55Z"},{"publication_status":"published","project":[{"_id":"25AD6156-B435-11E9-9278-68D0E5697425","name":"Modeling of Polarization and Motility of Leukocytes in Three-Dimensional Environments","grant_number":"LS13-029"},{"grant_number":"281556","call_identifier":"FP7","name":"Cytoskeletal force generation and force transduction of migrating leukocytes (EU)","_id":"25A603A2-B435-11E9-9278-68D0E5697425"}],"type":"journal_article","scopus_import":"1","abstract":[{"lang":"eng","text":"Actin filaments polymerizing against membranes power endocytosis, vesicular traffic, and cell motility. In vitro reconstitution studies suggest that the structure and the dynamics of actin networks respond to mechanical forces. We demonstrate that lamellipodial actin of migrating cells responds to mechanical load when membrane tension is modulated. In a steady state, migrating cell filaments assume the canonical dendritic geometry, defined by Arp2/3-generated 70° branch points. Increased tension triggers a dense network with a broadened range of angles, whereas decreased tension causes a shift to a sparse configuration dominated by filaments growing perpendicularly to the plasma membrane. We show that these responses emerge from the geometry of branched actin: when load per filament decreases, elongation speed increases and perpendicular filaments gradually outcompete others because they polymerize the shortest distance to the membrane, where they are protected from capping. This network-intrinsic geometrical adaptation mechanism tunes protrusive force in response to mechanical load."}],"citation":{"apa":"Mueller, J., Szep, G., Nemethova, M., de Vries, I., Lieber, A., Winkler, C., … Sixt, M. K. (2017). Load adaptation of lamellipodial actin networks. <i>Cell</i>. Cell Press. <a href=\"https://doi.org/10.1016/j.cell.2017.07.051\">https://doi.org/10.1016/j.cell.2017.07.051</a>","mla":"Mueller, Jan, et al. “Load Adaptation of Lamellipodial Actin Networks.” <i>Cell</i>, vol. 171, no. 1, Cell Press, 2017, pp. 188–200, doi:<a href=\"https://doi.org/10.1016/j.cell.2017.07.051\">10.1016/j.cell.2017.07.051</a>.","ama":"Mueller J, Szep G, Nemethova M, et al. Load adaptation of lamellipodial actin networks. <i>Cell</i>. 2017;171(1):188-200. doi:<a href=\"https://doi.org/10.1016/j.cell.2017.07.051\">10.1016/j.cell.2017.07.051</a>","short":"J. Mueller, G. Szep, M. Nemethova, I. de Vries, A. Lieber, C. Winkler, K. Kruse, J. Small, C. Schmeiser, K. Keren, R. Hauschild, M.K. Sixt, Cell 171 (2017) 188–200.","ista":"Mueller J, Szep G, Nemethova M, de Vries I, Lieber A, Winkler C, Kruse K, Small J, Schmeiser C, Keren K, Hauschild R, Sixt MK. 2017. Load adaptation of lamellipodial actin networks. Cell. 171(1), 188–200.","ieee":"J. Mueller <i>et al.</i>, “Load adaptation of lamellipodial actin networks,” <i>Cell</i>, vol. 171, no. 1. Cell Press, pp. 188–200, 2017.","chicago":"Mueller, Jan, Gregory Szep, Maria Nemethova, Ingrid de Vries, Arnon Lieber, Christoph Winkler, Karsten Kruse, et al. “Load Adaptation of Lamellipodial Actin Networks.” <i>Cell</i>. Cell Press, 2017. <a href=\"https://doi.org/10.1016/j.cell.2017.07.051\">https://doi.org/10.1016/j.cell.2017.07.051</a>."},"publication_identifier":{"issn":["00928674"]},"quality_controlled":"1","_id":"727","publist_id":"6951","department":[{"_id":"MiSi"},{"_id":"Bio"}],"article_processing_charge":"No","language":[{"iso":"eng"}],"publisher":"Cell Press","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","title":"Load adaptation of lamellipodial actin networks","author":[{"first_name":"Jan","last_name":"Mueller","full_name":"Mueller, Jan"},{"full_name":"Szep, Gregory","last_name":"Szep","first_name":"Gregory","id":"4BFB7762-F248-11E8-B48F-1D18A9856A87"},{"id":"34E27F1C-F248-11E8-B48F-1D18A9856A87","first_name":"Maria","last_name":"Nemethova","full_name":"Nemethova, Maria"},{"full_name":"De Vries, Ingrid","last_name":"De Vries","id":"4C7D837E-F248-11E8-B48F-1D18A9856A87","first_name":"Ingrid"},{"last_name":"Lieber","first_name":"Arnon","full_name":"Lieber, Arnon"},{"first_name":"Christoph","last_name":"Winkler","full_name":"Winkler, Christoph"},{"last_name":"Kruse","first_name":"Karsten","full_name":"Kruse, Karsten"},{"full_name":"Small, John","first_name":"John","last_name":"Small"},{"last_name":"Schmeiser","first_name":"Christian","full_name":"Schmeiser, Christian"},{"first_name":"Kinneret","last_name":"Keren","full_name":"Keren, Kinneret"},{"full_name":"Hauschild, Robert","id":"4E01D6B4-F248-11E8-B48F-1D18A9856A87","first_name":"Robert","last_name":"Hauschild","orcid":"0000-0001-9843-3522"},{"first_name":"Michael K","id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87","last_name":"Sixt","orcid":"0000-0002-6620-9179","full_name":"Sixt, Michael K"}],"doi":"10.1016/j.cell.2017.07.051","publication":"Cell","isi":1,"oa_version":"None","ec_funded":1,"volume":171,"day":"21","status":"public","date_created":"2018-12-11T11:48:10Z","page":"188 - 200","external_id":{"isi":["000411331800020"]},"year":"2017","month":"09","intvolume":"       171","date_published":"2017-09-21T00:00:00Z","issue":"1","acknowledged_ssus":[{"_id":"ScienComp"}],"date_updated":"2023-09-28T11:33:49Z"},{"date_created":"2018-12-11T11:48:11Z","day":"18","status":"public","volume":27,"isi":1,"oa_version":"None","doi":"10.1016/j.cub.2017.07.010","publication":"Current Biology","date_updated":"2023-09-28T11:33:21Z","issue":"18","intvolume":"        27","month":"09","date_published":"2017-09-18T00:00:00Z","year":"2017","external_id":{"isi":["000411581800019"]},"page":"R1024 - R1035","_id":"728","quality_controlled":"1","publication_identifier":{"issn":["09609822"]},"citation":{"ieee":"C. Chan, C.-P. J. Heisenberg, and T. Hiiragi, “Coordination of morphogenesis and cell fate specification in development,” <i>Current Biology</i>, vol. 27, no. 18. Cell Press, pp. R1024–R1035, 2017.","ista":"Chan C, Heisenberg C-PJ, Hiiragi T. 2017. Coordination of morphogenesis and cell fate specification in development. Current Biology. 27(18), R1024–R1035.","short":"C. Chan, C.-P.J. Heisenberg, T. Hiiragi, Current Biology 27 (2017) R1024–R1035.","ama":"Chan C, Heisenberg C-PJ, Hiiragi T. Coordination of morphogenesis and cell fate specification in development. <i>Current Biology</i>. 2017;27(18):R1024-R1035. doi:<a href=\"https://doi.org/10.1016/j.cub.2017.07.010\">10.1016/j.cub.2017.07.010</a>","chicago":"Chan, Chii, Carl-Philipp J Heisenberg, and Takashi Hiiragi. “Coordination of Morphogenesis and Cell Fate Specification in Development.” <i>Current Biology</i>. Cell Press, 2017. <a href=\"https://doi.org/10.1016/j.cub.2017.07.010\">https://doi.org/10.1016/j.cub.2017.07.010</a>.","apa":"Chan, C., Heisenberg, C.-P. J., &#38; Hiiragi, T. (2017). Coordination of morphogenesis and cell fate specification in development. <i>Current Biology</i>. Cell Press. <a href=\"https://doi.org/10.1016/j.cub.2017.07.010\">https://doi.org/10.1016/j.cub.2017.07.010</a>","mla":"Chan, Chii, et al. “Coordination of Morphogenesis and Cell Fate Specification in Development.” <i>Current Biology</i>, vol. 27, no. 18, Cell Press, 2017, pp. R1024–35, doi:<a href=\"https://doi.org/10.1016/j.cub.2017.07.010\">10.1016/j.cub.2017.07.010</a>."},"type":"journal_article","abstract":[{"text":"During animal development, cell-fate-specific changes in gene expression can modify the material properties of a tissue and drive tissue morphogenesis. While mechanistic insights into the genetic control of tissue-shaping events are beginning to emerge, how tissue morphogenesis and mechanics can reciprocally impact cell-fate specification remains relatively unexplored. Here we review recent findings reporting how multicellular morphogenetic events and their underlying mechanical forces can feed back into gene regulatory pathways to specify cell fate. We further discuss emerging techniques that allow for the direct measurement and manipulation of mechanical signals in vivo, offering unprecedented access to study mechanotransduction during development. Examination of the mechanical control of cell fate during tissue morphogenesis will pave the way to an integrated understanding of the design principles that underlie robust tissue patterning in embryonic development.","lang":"eng"}],"scopus_import":"1","publication_status":"published","author":[{"full_name":"Chan, Chii","first_name":"Chii","last_name":"Chan"},{"first_name":"Carl-Philipp J","id":"39427864-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-0912-4566","last_name":"Heisenberg","full_name":"Heisenberg, Carl-Philipp J"},{"full_name":"Hiiragi, Takashi","first_name":"Takashi","last_name":"Hiiragi"}],"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","title":"Coordination of morphogenesis and cell fate specification in development","publisher":"Cell Press","language":[{"iso":"eng"}],"article_processing_charge":"No","department":[{"_id":"CaHe"}],"publist_id":"6949"},{"language":[{"iso":"eng"}],"article_type":"original","year":"2017","article_processing_charge":"No","page":"393-404","date_updated":"2021-06-10T06:17:17Z","title":"Biredox ionic liquids: New opportunities toward high performance supercapacitors","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","author":[{"full_name":"Bodin, C.","last_name":"Bodin","first_name":"C."},{"full_name":"Mourad, E.","first_name":"E.","last_name":"Mourad"},{"first_name":"D.","last_name":"Zigah","full_name":"Zigah, D."},{"full_name":"Le Vot, S.","last_name":"Le Vot","first_name":"S."},{"last_name":"Freunberger","orcid":"0000-0003-2902-5319","first_name":"Stefan Alexander","id":"A8CA28E6-CE23-11E9-AD2D-EC27E6697425","full_name":"Freunberger, Stefan Alexander"},{"full_name":"Favier, F.","last_name":"Favier","first_name":"F."},{"full_name":"Fontaine, O.","last_name":"Fontaine","first_name":"O."}],"date_published":"2017-06-29T00:00:00Z","intvolume":"       206","month":"06","publisher":"Royal Society of Chemistry","oa_version":"None","publication":"Faraday Discussions","publication_status":"published","doi":"10.1039/c7fd00174f","date_created":"2020-01-15T12:14:04Z","_id":"7288","day":"29","quality_controlled":"1","status":"public","volume":206,"publication_identifier":{"issn":["1359-6640","1364-5498"]},"extern":"1","citation":{"short":"C. Bodin, E. Mourad, D. Zigah, S. Le Vot, S.A. Freunberger, F. Favier, O. Fontaine, Faraday Discussions 206 (2017) 393–404.","ista":"Bodin C, Mourad E, Zigah D, Le Vot S, Freunberger SA, Favier F, Fontaine O. 2017. Biredox ionic liquids: New opportunities toward high performance supercapacitors. Faraday Discussions. 206, 393–404.","ieee":"C. Bodin <i>et al.</i>, “Biredox ionic liquids: New opportunities toward high performance supercapacitors,” <i>Faraday Discussions</i>, vol. 206. Royal Society of Chemistry, pp. 393–404, 2017.","ama":"Bodin C, Mourad E, Zigah D, et al. Biredox ionic liquids: New opportunities toward high performance supercapacitors. <i>Faraday Discussions</i>. 2017;206:393-404. doi:<a href=\"https://doi.org/10.1039/c7fd00174f\">10.1039/c7fd00174f</a>","chicago":"Bodin, C., E. Mourad, D. Zigah, S. Le Vot, Stefan Alexander Freunberger, F. Favier, and O. Fontaine. “Biredox Ionic Liquids: New Opportunities toward High Performance Supercapacitors.” <i>Faraday Discussions</i>. Royal Society of Chemistry, 2017. <a href=\"https://doi.org/10.1039/c7fd00174f\">https://doi.org/10.1039/c7fd00174f</a>.","apa":"Bodin, C., Mourad, E., Zigah, D., Le Vot, S., Freunberger, S. A., Favier, F., &#38; Fontaine, O. (2017). Biredox ionic liquids: New opportunities toward high performance supercapacitors. <i>Faraday Discussions</i>. Royal Society of Chemistry. <a href=\"https://doi.org/10.1039/c7fd00174f\">https://doi.org/10.1039/c7fd00174f</a>","mla":"Bodin, C., et al. “Biredox Ionic Liquids: New Opportunities toward High Performance Supercapacitors.” <i>Faraday Discussions</i>, vol. 206, Royal Society of Chemistry, 2017, pp. 393–404, doi:<a href=\"https://doi.org/10.1039/c7fd00174f\">10.1039/c7fd00174f</a>."},"abstract":[{"text":"Nowadays commercial supercapacitors are based on purely capacitive storage at the porous carbons that are used for the electrodes. However, the limits that capacitive storage imposes on energy density calls to investigate new materials to improve the capacitance of the device. This new type of electrodes (e.g., RuO2, MnO2…) involves pseudo-capacitive faradaic redox processes with the solid material. Ion exchange with solid materials is, however, much slower than the adsorption process in capacitive storage and inevitably leads to significant loss of power. Faradaic process in the liquid state, in contrast can be similarly fast as capacitive processes due to the fast ion transport. Designing new devices with liquid like dynamics and improved specific capacitance is challenging. We present a new approach to increase the specific capacitance using biredox ionic liquids, where redox moieties are tethered to the electrolyte ions, allowing high redox concentrations and significant pseudo-capacitive storage in the liquid state. Anions and cations are functionalized with anthraquinone (AQ) and 2,2,6,6-tetramethylpiperidinyl-1-oxyl (TEMPO) moieties, respectively. Glassy carbon, carbon-onion, and commercial activated carbon electrodes that exhibit different double layer structures and thus different diffusion dynamics were used to simultaneously study the electrochemical response of biredox ionic liquids at the positive and negative electrode.","lang":"eng"}],"type":"journal_article"},{"citation":{"chicago":"Schafzahl, Lukas, Nika Mahne, Bettina Schafzahl, Martin Wilkening, Christian Slugovc, Sergey M. Borisov, and Stefan Alexander Freunberger. “Singlet Oxygen during Cycling of the Aprotic Sodium-O2 Battery.” <i>Angewandte Chemie International Edition</i>. Wiley, 2017. <a href=\"https://doi.org/10.1002/anie.201709351\">https://doi.org/10.1002/anie.201709351</a>.","short":"L. Schafzahl, N. Mahne, B. Schafzahl, M. Wilkening, C. Slugovc, S.M. Borisov, S.A. Freunberger, Angewandte Chemie International Edition 56 (2017) 15728–15732.","ieee":"L. Schafzahl <i>et al.</i>, “Singlet oxygen during cycling of the aprotic sodium-O2 battery,” <i>Angewandte Chemie International Edition</i>, vol. 56, no. 49. Wiley, pp. 15728–15732, 2017.","ista":"Schafzahl L, Mahne N, Schafzahl B, Wilkening M, Slugovc C, Borisov SM, Freunberger SA. 2017. Singlet oxygen during cycling of the aprotic sodium-O2 battery. Angewandte Chemie International Edition. 56(49), 15728–15732.","ama":"Schafzahl L, Mahne N, Schafzahl B, et al. Singlet oxygen during cycling of the aprotic sodium-O2 battery. <i>Angewandte Chemie International Edition</i>. 2017;56(49):15728-15732. doi:<a href=\"https://doi.org/10.1002/anie.201709351\">10.1002/anie.201709351</a>","mla":"Schafzahl, Lukas, et al. “Singlet Oxygen during Cycling of the Aprotic Sodium-O2 Battery.” <i>Angewandte Chemie International Edition</i>, vol. 56, no. 49, Wiley, 2017, pp. 15728–32, doi:<a href=\"https://doi.org/10.1002/anie.201709351\">10.1002/anie.201709351</a>.","apa":"Schafzahl, L., Mahne, N., Schafzahl, B., Wilkening, M., Slugovc, C., Borisov, S. M., &#38; Freunberger, S. A. (2017). Singlet oxygen during cycling of the aprotic sodium-O2 battery. <i>Angewandte Chemie International Edition</i>. Wiley. <a href=\"https://doi.org/10.1002/anie.201709351\">https://doi.org/10.1002/anie.201709351</a>"},"extern":"1","publication_identifier":{"issn":["1433-7851"]},"file_date_updated":"2020-07-14T12:47:55Z","type":"journal_article","abstract":[{"lang":"eng","text":"Aprotic sodium–O2 batteries require the reversible formation/dissolution of sodium superoxide (NaO2) on cycling. Poor cycle life has been associated with parasitic chemistry caused by the reactivity of electrolyte and electrode with NaO2, a strong nucleophile and base. Its reactivity can, however, not consistently explain the side reactions and irreversibility. Herein we show that singlet oxygen (1O2) forms at all stages of cycling and that it is a main driver for parasitic chemistry. It was detected in‐ and ex‐situ via a 1O2 trap that selectively and rapidly forms a stable adduct with 1O2. The 1O2 formation mechanism involves proton‐mediated superoxide disproportionation on discharge, rest, and charge below ca. 3.3 V, and direct electrochemical 1O2 evolution above ca. 3.3 V. Trace water, which is needed for high capacities also drives parasitic chemistry. Controlling the highly reactive singlet oxygen is thus crucial for achieving highly reversible cell operation."}],"_id":"7289","quality_controlled":"1","publication_status":"published","has_accepted_license":"1","publisher":"Wiley","file":[{"date_created":"2020-01-26T14:58:07Z","date_updated":"2020-07-14T12:47:55Z","file_name":"2017_AngChemieInternat_Schafzahl.pdf","checksum":"3c5b1e51954554dffb13c7d58f69836c","access_level":"open_access","relation":"main_file","file_size":1013492,"creator":"dernst","content_type":"application/pdf","file_id":"7362"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Singlet oxygen during cycling of the aprotic sodium-O2 battery","author":[{"full_name":"Schafzahl, Lukas","first_name":"Lukas","last_name":"Schafzahl"},{"last_name":"Mahne","first_name":"Nika","full_name":"Mahne, Nika"},{"full_name":"Schafzahl, Bettina","last_name":"Schafzahl","first_name":"Bettina"},{"full_name":"Wilkening, Martin","first_name":"Martin","last_name":"Wilkening"},{"full_name":"Slugovc, Christian","first_name":"Christian","last_name":"Slugovc"},{"full_name":"Borisov, Sergey M.","first_name":"Sergey M.","last_name":"Borisov"},{"full_name":"Freunberger, Stefan Alexander","first_name":"Stefan Alexander","id":"A8CA28E6-CE23-11E9-AD2D-EC27E6697425","last_name":"Freunberger","orcid":"0000-0003-2902-5319"}],"article_processing_charge":"No","language":[{"iso":"eng"}],"article_type":"original","volume":56,"tmp":{"short":"CC BY-NC (4.0)","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","image":"/images/cc_by_nc.png"},"ddc":["540"],"date_created":"2020-01-15T12:15:05Z","day":"04","status":"public","doi":"10.1002/anie.201709351","publication":"Angewandte Chemie International Edition","oa_version":"Published Version","intvolume":"        56","month":"12","date_published":"2017-12-04T00:00:00Z","date_updated":"2021-01-12T08:12:47Z","issue":"49","oa":1,"page":"15728-15732","year":"2017"},{"publisher":"Cell Press","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","author":[{"last_name":"Spiro","first_name":"Zoltan P","id":"426AD026-F248-11E8-B48F-1D18A9856A87","full_name":"Spiro, Zoltan P"},{"full_name":"Heisenberg, Carl-Philipp J","orcid":"0000-0002-0912-4566","last_name":"Heisenberg","first_name":"Carl-Philipp J","id":"39427864-F248-11E8-B48F-1D18A9856A87"}],"title":"Regeneration tensed up polyploidy takes the lead","publist_id":"6948","department":[{"_id":"CaHe"}],"article_processing_charge":"No","language":[{"iso":"eng"}],"type":"journal_article","abstract":[{"lang":"eng","text":"The cellular mechanisms allowing tissues to efficiently regenerate are not fully understood. In this issue of Developmental Cell, Cao et al. (2017)) discover that during zebrafish heart regeneration, epicardial cells at the leading edge of regenerating tissue undergo endoreplication, possibly due to increased tissue tension, thereby boosting their regenerative capacity."}],"scopus_import":"1","publication_identifier":{"issn":["15345807"]},"citation":{"chicago":"Spiro, Zoltan P, and Carl-Philipp J Heisenberg. “Regeneration Tensed up Polyploidy Takes the Lead.” <i>Developmental Cell</i>. Cell Press, 2017. <a href=\"https://doi.org/10.1016/j.devcel.2017.09.008\">https://doi.org/10.1016/j.devcel.2017.09.008</a>.","ama":"Spiro ZP, Heisenberg C-PJ. Regeneration tensed up polyploidy takes the lead. <i>Developmental Cell</i>. 2017;42(6):559-560. doi:<a href=\"https://doi.org/10.1016/j.devcel.2017.09.008\">10.1016/j.devcel.2017.09.008</a>","ieee":"Z. P. Spiro and C.-P. J. Heisenberg, “Regeneration tensed up polyploidy takes the lead,” <i>Developmental Cell</i>, vol. 42, no. 6. Cell Press, pp. 559–560, 2017.","ista":"Spiro ZP, Heisenberg C-PJ. 2017. Regeneration tensed up polyploidy takes the lead. Developmental Cell. 42(6), 559–560.","short":"Z.P. Spiro, C.-P.J. Heisenberg, Developmental Cell 42 (2017) 559–560.","mla":"Spiro, Zoltan P., and Carl-Philipp J. Heisenberg. “Regeneration Tensed up Polyploidy Takes the Lead.” <i>Developmental Cell</i>, vol. 42, no. 6, Cell Press, 2017, pp. 559–60, doi:<a href=\"https://doi.org/10.1016/j.devcel.2017.09.008\">10.1016/j.devcel.2017.09.008</a>.","apa":"Spiro, Z. P., &#38; Heisenberg, C.-P. J. (2017). Regeneration tensed up polyploidy takes the lead. <i>Developmental Cell</i>. Cell Press. <a href=\"https://doi.org/10.1016/j.devcel.2017.09.008\">https://doi.org/10.1016/j.devcel.2017.09.008</a>"},"quality_controlled":"1","_id":"729","publication_status":"published","intvolume":"        42","month":"01","date_published":"2017-01-01T00:00:00Z","issue":"6","date_updated":"2023-09-28T11:32:49Z","external_id":{"isi":["000411582800003"]},"page":"559 - 560","year":"2017","volume":42,"day":"01","status":"public","date_created":"2018-12-11T11:48:11Z","doi":"10.1016/j.devcel.2017.09.008","publication":"Developmental Cell","isi":1,"oa_version":"None"},{"month":"10","intvolume":"         9","date_published":"2017-10-10T00:00:00Z","issue":"43","oa":1,"date_updated":"2021-01-12T08:12:48Z","page":"38008-38023","year":"2017","volume":9,"status":"public","day":"10","ddc":["540","543"],"date_created":"2020-01-15T12:15:16Z","doi":"10.1021/acsami.7b10669","publication":"ACS Applied Materials & Interfaces","oa_version":"Submitted Version","publisher":"ACS","has_accepted_license":"1","file":[{"content_type":"application/pdf","file_id":"8051","file_size":2072792,"creator":"sfreunbe","access_level":"open_access","relation":"main_file","checksum":"0461c990eb910f19a70c6e5349ec35ed","file_name":"Paper_Manuscript_submitted.pdf","date_created":"2020-06-29T14:49:32Z","date_updated":"2020-07-14T12:47:55Z"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","author":[{"full_name":"Zach, Peter W.","last_name":"Zach","first_name":"Peter W."},{"full_name":"Freunberger, Stefan Alexander","orcid":"0000-0003-2902-5319","last_name":"Freunberger","id":"A8CA28E6-CE23-11E9-AD2D-EC27E6697425","first_name":"Stefan Alexander"},{"full_name":"Klimant, Ingo","last_name":"Klimant","first_name":"Ingo"},{"first_name":"Sergey M.","last_name":"Borisov","full_name":"Borisov, Sergey M."}],"title":"Electron-deficient near-infrared Pt(II) and Pd(II) benzoporphyrins with dual phosphorescence and unusually efficient thermally activated delayed fluorescence: First demonstration of simultaneous oxygen and temperature sensing with a single emitter","article_processing_charge":"No","article_type":"original","language":[{"iso":"eng"}],"type":"journal_article","file_date_updated":"2020-07-14T12:47:55Z","abstract":[{"lang":"eng","text":"We report a family of Pt and Pd benzoporphyrin dyes with versatile photophysical properties and easy access from cheap and abundant chemicals. Attaching 4 or 8 alkylsulfone groups onto a meso-tetraphenyltetrabenzoporphyrin (TPTBP) macrocylcle renders the dyes highly soluble in organic solvents, photostable, and electron-deficient with the redox potential raised up to 0.65 V versus the parent porphyrin. The new dyes intensively absorb in the blue (Soret band, 440–480 nm) and in the red (Q-band, 620–650 nm) parts of the electromagnetic spectrum and show bright phosphorescence at room-temperature in the NIR with quantum yields up to 30% in solution. The small singlet–triplet energy gap yields unusually efficient thermally activated delayed fluorescence (TADF) at elevated temperatures in solution and in polymeric matrices with quantum yields as high as 27% at 120 °C, which is remarkable for benzoporphyrins. Apart from oxygen sensing, these properties enable unprecedented simultaneous, self-referenced oxygen and temperature sensing with a single indicator dye: whereas oxygen can be determined either via the decay time of phosphorescence or TADF, the temperature is accessed via the ratio of the two emissions. Moreover, the dyes are efficient sensitizers for triplet–triplet annihilation (TTA)-based upconversion making possible longer sensitization wavelength than the conventional benzoporphyrin complexes. The Pt-octa-sulfone dye also features interesting semireversible transformation in basic media, which generates new NIR absorbing species."}],"extern":"1","publication_identifier":{"issn":["1944-8244"],"eissn":["1944-8252"]},"citation":{"apa":"Zach, P. W., Freunberger, S. A., Klimant, I., &#38; Borisov, S. M. (2017). Electron-deficient near-infrared Pt(II) and Pd(II) benzoporphyrins with dual phosphorescence and unusually efficient thermally activated delayed fluorescence: First demonstration of simultaneous oxygen and temperature sensing with a single emitter. <i>ACS Applied Materials &#38; Interfaces</i>. ACS. <a href=\"https://doi.org/10.1021/acsami.7b10669\">https://doi.org/10.1021/acsami.7b10669</a>","mla":"Zach, Peter W., et al. “Electron-Deficient near-Infrared Pt(II) and Pd(II) Benzoporphyrins with Dual Phosphorescence and Unusually Efficient Thermally Activated Delayed Fluorescence: First Demonstration of Simultaneous Oxygen and Temperature Sensing with a Single Emitter.” <i>ACS Applied Materials &#38; Interfaces</i>, vol. 9, no. 43, ACS, 2017, pp. 38008–23, doi:<a href=\"https://doi.org/10.1021/acsami.7b10669\">10.1021/acsami.7b10669</a>.","ama":"Zach PW, Freunberger SA, Klimant I, Borisov SM. Electron-deficient near-infrared Pt(II) and Pd(II) benzoporphyrins with dual phosphorescence and unusually efficient thermally activated delayed fluorescence: First demonstration of simultaneous oxygen and temperature sensing with a single emitter. <i>ACS Applied Materials &#38; Interfaces</i>. 2017;9(43):38008-38023. doi:<a href=\"https://doi.org/10.1021/acsami.7b10669\">10.1021/acsami.7b10669</a>","short":"P.W. Zach, S.A. Freunberger, I. Klimant, S.M. Borisov, ACS Applied Materials &#38; Interfaces 9 (2017) 38008–38023.","ista":"Zach PW, Freunberger SA, Klimant I, Borisov SM. 2017. Electron-deficient near-infrared Pt(II) and Pd(II) benzoporphyrins with dual phosphorescence and unusually efficient thermally activated delayed fluorescence: First demonstration of simultaneous oxygen and temperature sensing with a single emitter. ACS Applied Materials &#38; Interfaces. 9(43), 38008–38023.","ieee":"P. W. Zach, S. A. Freunberger, I. Klimant, and S. M. Borisov, “Electron-deficient near-infrared Pt(II) and Pd(II) benzoporphyrins with dual phosphorescence and unusually efficient thermally activated delayed fluorescence: First demonstration of simultaneous oxygen and temperature sensing with a single emitter,” <i>ACS Applied Materials &#38; Interfaces</i>, vol. 9, no. 43. ACS, pp. 38008–38023, 2017.","chicago":"Zach, Peter W., Stefan Alexander Freunberger, Ingo Klimant, and Sergey M. Borisov. “Electron-Deficient near-Infrared Pt(II) and Pd(II) Benzoporphyrins with Dual Phosphorescence and Unusually Efficient Thermally Activated Delayed Fluorescence: First Demonstration of Simultaneous Oxygen and Temperature Sensing with a Single Emitter.” <i>ACS Applied Materials &#38; Interfaces</i>. ACS, 2017. <a href=\"https://doi.org/10.1021/acsami.7b10669\">https://doi.org/10.1021/acsami.7b10669</a>."},"quality_controlled":"1","_id":"7290","publication_status":"published"},{"oa_version":"None","publication":"ChemSusChem","publication_status":"published","doi":"10.1002/cssc.201601222","_id":"7291","date_created":"2020-01-15T12:15:29Z","day":"20","status":"public","quality_controlled":"1","volume":10,"extern":"1","citation":{"chicago":"Schafzahl, Lukas, Ilie Hanzu, Martin Wilkening, and Stefan Alexander Freunberger. “An Electrolyte for Reversible Cycling of Sodium Metal and Intercalation Compounds.” <i>ChemSusChem</i>. Wiley, 2017. <a href=\"https://doi.org/10.1002/cssc.201601222\">https://doi.org/10.1002/cssc.201601222</a>.","ista":"Schafzahl L, Hanzu I, Wilkening M, Freunberger SA. 2017. An electrolyte for reversible cycling of sodium metal and intercalation compounds. ChemSusChem. 10(2), 401–408.","ieee":"L. Schafzahl, I. Hanzu, M. Wilkening, and S. A. Freunberger, “An electrolyte for reversible cycling of sodium metal and intercalation compounds,” <i>ChemSusChem</i>, vol. 10, no. 2. Wiley, pp. 401–408, 2017.","short":"L. Schafzahl, I. Hanzu, M. Wilkening, S.A. Freunberger, ChemSusChem 10 (2017) 401–408.","ama":"Schafzahl L, Hanzu I, Wilkening M, Freunberger SA. An electrolyte for reversible cycling of sodium metal and intercalation compounds. <i>ChemSusChem</i>. 2017;10(2):401-408. doi:<a href=\"https://doi.org/10.1002/cssc.201601222\">10.1002/cssc.201601222</a>","mla":"Schafzahl, Lukas, et al. “An Electrolyte for Reversible Cycling of Sodium Metal and Intercalation Compounds.” <i>ChemSusChem</i>, vol. 10, no. 2, Wiley, 2017, pp. 401–08, doi:<a href=\"https://doi.org/10.1002/cssc.201601222\">10.1002/cssc.201601222</a>.","apa":"Schafzahl, L., Hanzu, I., Wilkening, M., &#38; Freunberger, S. A. (2017). An electrolyte for reversible cycling of sodium metal and intercalation compounds. <i>ChemSusChem</i>. Wiley. <a href=\"https://doi.org/10.1002/cssc.201601222\">https://doi.org/10.1002/cssc.201601222</a>"},"publication_identifier":{"issn":["1864-5631"]},"abstract":[{"text":"Na battery chemistries show poor passivation behavior of low voltage Na storage compounds and Na metal with organic carbonate‐based electrolytes adopted from Li‐ion batteries. Therefore, a suitable electrolyte remains a major challenge for establishing Na batteries. Here we report highly concentrated sodium bis(fluorosulfonyl)imide (NaFSI) in dimethoxyethane (DME) electrolytes and investigate them for Na metal and hard carbon anodes and intercalation cathodes. For a DME/NaFSI ratio of 2, a stable passivation of anode materials was found owing to the formation of a stable solid electrolyte interface, which was characterized spectroscopically. This permitted non‐dentritic Na metal cycling with approximately 98 % coulombic efficiency as shown for up to 300 cycles. The NaFSI/DME electrolyte may enable Na‐metal anodes and allows for more reliable assessment of electrode materials in Na‐ion half‐cells, as is demonstrated by comparing half‐cell cycling of hard carbon anodes and Na3V2(PO4)3 cathodes with a widely used carbonate and the NaFSI/DME electrolyte.","lang":"eng"}],"type":"journal_article","language":[{"iso":"eng"}],"article_type":"original","year":"2017","article_processing_charge":"No","page":"401-408","date_updated":"2021-01-12T08:12:48Z","title":"An electrolyte for reversible cycling of sodium metal and intercalation compounds","author":[{"full_name":"Schafzahl, Lukas","last_name":"Schafzahl","first_name":"Lukas"},{"last_name":"Hanzu","first_name":"Ilie","full_name":"Hanzu, Ilie"},{"first_name":"Martin","last_name":"Wilkening","full_name":"Wilkening, Martin"},{"first_name":"Stefan Alexander","id":"A8CA28E6-CE23-11E9-AD2D-EC27E6697425","orcid":"0000-0003-2902-5319","last_name":"Freunberger","full_name":"Freunberger, Stefan Alexander"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","issue":"2","date_published":"2017-01-20T00:00:00Z","intvolume":"        10","month":"01","publisher":"Wiley"},{"file":[{"file_id":"7363","content_type":"application/pdf","file_size":992106,"creator":"dernst","relation":"main_file","access_level":"open_access","checksum":"70c7c2ce5430b6e8605ccbf0275f1e80","file_name":"2017_ChemicalScience_Mahne.pdf","date_created":"2020-01-26T15:04:44Z","date_updated":"2020-07-14T12:47:55Z"}],"title":"Mechanism and performance of lithium–oxygen batteries – a perspective","author":[{"last_name":"Mahne","first_name":"Nika","full_name":"Mahne, Nika"},{"first_name":"Olivier","last_name":"Fontaine","full_name":"Fontaine, Olivier"},{"full_name":"Thotiyl, Musthafa Ottakam","last_name":"Thotiyl","first_name":"Musthafa Ottakam"},{"full_name":"Wilkening, Martin","last_name":"Wilkening","first_name":"Martin"},{"orcid":"0000-0003-2902-5319","last_name":"Freunberger","id":"A8CA28E6-CE23-11E9-AD2D-EC27E6697425","first_name":"Stefan Alexander","full_name":"Freunberger, Stefan Alexander"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"RSC","has_accepted_license":"1","article_type":"original","language":[{"iso":"eng"}],"article_processing_charge":"No","quality_controlled":"1","_id":"7292","type":"journal_article","file_date_updated":"2020-07-14T12:47:55Z","abstract":[{"lang":"eng","text":"Rechargeable Li–O2 batteries have amongst the highest formal energy and could store significantly more energy than other rechargeable batteries in practice if at least a large part of their promise could be realized. Realization, however, still faces many challenges than can only be overcome by fundamental understanding of the processes taking place. Here, we review recent advances in understanding the chemistry of the Li–O2 cathode and provide a perspective on dominant research needs. We put particular emphasis on issues that are often grossly misunderstood: realistic performance metrics and their reporting as well as identifying reversibility and quantitative measures to do so. Parasitic reactions are the prime obstacle for reversible cell operation and have recently been identified to be predominantly caused by singlet oxygen and not by reduced oxygen species as thought before. We discuss the far reaching implications of this finding on electrolyte and cathode stability, electrocatalysis, and future research needs."}],"citation":{"chicago":"Mahne, Nika, Olivier Fontaine, Musthafa Ottakam Thotiyl, Martin Wilkening, and Stefan Alexander Freunberger. “Mechanism and Performance of Lithium–Oxygen Batteries – a Perspective.” <i>Chemical Science</i>. RSC, 2017. <a href=\"https://doi.org/10.1039/c7sc02519j\">https://doi.org/10.1039/c7sc02519j</a>.","short":"N. Mahne, O. Fontaine, M.O. Thotiyl, M. Wilkening, S.A. Freunberger, Chemical Science 8 (2017) 6716–6729.","ista":"Mahne N, Fontaine O, Thotiyl MO, Wilkening M, Freunberger SA. 2017. Mechanism and performance of lithium–oxygen batteries – a perspective. Chemical Science. 8(10), 6716–6729.","ieee":"N. Mahne, O. Fontaine, M. O. Thotiyl, M. Wilkening, and S. A. Freunberger, “Mechanism and performance of lithium–oxygen batteries – a perspective,” <i>Chemical Science</i>, vol. 8, no. 10. RSC, pp. 6716–6729, 2017.","ama":"Mahne N, Fontaine O, Thotiyl MO, Wilkening M, Freunberger SA. Mechanism and performance of lithium–oxygen batteries – a perspective. <i>Chemical Science</i>. 2017;8(10):6716-6729. doi:<a href=\"https://doi.org/10.1039/c7sc02519j\">10.1039/c7sc02519j</a>","mla":"Mahne, Nika, et al. “Mechanism and Performance of Lithium–Oxygen Batteries – a Perspective.” <i>Chemical Science</i>, vol. 8, no. 10, RSC, 2017, pp. 6716–29, doi:<a href=\"https://doi.org/10.1039/c7sc02519j\">10.1039/c7sc02519j</a>.","apa":"Mahne, N., Fontaine, O., Thotiyl, M. O., Wilkening, M., &#38; Freunberger, S. A. (2017). Mechanism and performance of lithium–oxygen batteries – a perspective. <i>Chemical Science</i>. RSC. <a href=\"https://doi.org/10.1039/c7sc02519j\">https://doi.org/10.1039/c7sc02519j</a>"},"publication_identifier":{"eissn":["2041-6539"],"issn":["2041-6520"]},"extern":"1","publication_status":"published","issue":"10","oa":1,"date_updated":"2021-01-12T08:12:49Z","intvolume":"         8","month":"07","date_published":"2017-07-31T00:00:00Z","year":"2017","page":"6716-6729","status":"public","day":"31","ddc":["540"],"tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"date_created":"2020-01-15T12:15:42Z","volume":8,"oa_version":"Published Version","doi":"10.1039/c7sc02519j","publication":"Chemical Science"},{"_id":"730","quality_controlled":"1","publication_identifier":{"issn":["09594388"]},"citation":{"apa":"Savin, C., &#38; Tkačik, G. (2017). Maximum entropy models as a tool for building precise neural controls. <i>Current Opinion in Neurobiology</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.conb.2017.08.001\">https://doi.org/10.1016/j.conb.2017.08.001</a>","mla":"Savin, Cristina, and Gašper Tkačik. “Maximum Entropy Models as a Tool for Building Precise Neural Controls.” <i>Current Opinion in Neurobiology</i>, vol. 46, Elsevier, 2017, pp. 120–26, doi:<a href=\"https://doi.org/10.1016/j.conb.2017.08.001\">10.1016/j.conb.2017.08.001</a>.","ista":"Savin C, Tkačik G. 2017. Maximum entropy models as a tool for building precise neural controls. Current Opinion in Neurobiology. 46, 120–126.","ieee":"C. Savin and G. Tkačik, “Maximum entropy models as a tool for building precise neural controls,” <i>Current Opinion in Neurobiology</i>, vol. 46. Elsevier, pp. 120–126, 2017.","short":"C. Savin, G. Tkačik, Current Opinion in Neurobiology 46 (2017) 120–126.","ama":"Savin C, Tkačik G. Maximum entropy models as a tool for building precise neural controls. <i>Current Opinion in Neurobiology</i>. 2017;46:120-126. doi:<a href=\"https://doi.org/10.1016/j.conb.2017.08.001\">10.1016/j.conb.2017.08.001</a>","chicago":"Savin, Cristina, and Gašper Tkačik. “Maximum Entropy Models as a Tool for Building Precise Neural Controls.” <i>Current Opinion in Neurobiology</i>. Elsevier, 2017. <a href=\"https://doi.org/10.1016/j.conb.2017.08.001\">https://doi.org/10.1016/j.conb.2017.08.001</a>."},"type":"journal_article","abstract":[{"text":"Neural responses are highly structured, with population activity restricted to a small subset of the astronomical range of possible activity patterns. Characterizing these statistical regularities is important for understanding circuit computation, but challenging in practice. Here we review recent approaches based on the maximum entropy principle used for quantifying collective behavior in neural activity. We highlight recent models that capture population-level statistics of neural data, yielding insights into the organization of the neural code and its biological substrate. Furthermore, the MaxEnt framework provides a general recipe for constructing surrogate ensembles that preserve aspects of the data, but are otherwise maximally unstructured. This idea can be used to generate a hierarchy of controls against which rigorous statistical tests are possible.","lang":"eng"}],"scopus_import":"1","project":[{"call_identifier":"FP7","grant_number":"291734","_id":"25681D80-B435-11E9-9278-68D0E5697425","name":"International IST Postdoc Fellowship Programme"}],"publication_status":"published","title":"Maximum entropy models as a tool for building precise neural controls","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","author":[{"full_name":"Savin, Cristina","id":"3933349E-F248-11E8-B48F-1D18A9856A87","first_name":"Cristina","last_name":"Savin"},{"last_name":"Tkacik","orcid":"0000-0002-6699-1455","first_name":"Gasper","id":"3D494DCA-F248-11E8-B48F-1D18A9856A87","full_name":"Tkacik, Gasper"}],"publisher":"Elsevier","language":[{"iso":"eng"}],"article_processing_charge":"No","publist_id":"6943","department":[{"_id":"GaTk"}],"date_created":"2018-12-11T11:48:11Z","day":"01","status":"public","volume":46,"isi":1,"oa_version":"None","ec_funded":1,"doi":"10.1016/j.conb.2017.08.001","publication":"Current Opinion in Neurobiology","date_updated":"2023-09-28T11:32:22Z","intvolume":"        46","month":"10","date_published":"2017-10-01T00:00:00Z","year":"2017","external_id":{"isi":["000416196400016"]},"page":"120 - 126"},{"year":"2017","language":[{"iso":"eng"}],"department":[{"_id":"GaNo"}],"publist_id":"6938","author":[{"orcid":"0000-0002-7673-7178","last_name":"Novarino","first_name":"Gaia","id":"3E57A680-F248-11E8-B48F-1D18A9856A87","full_name":"Novarino, Gaia"}],"title":"The science of love in ASD and ADHD","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","issue":"411","date_updated":"2021-01-12T08:12:57Z","article_number":"eaap8168","publisher":"American Association for the Advancement of Science","date_published":"2017-10-11T00:00:00Z","month":"10","intvolume":"         9","oa_version":"None","publication":"Science Translational Medicine","publication_status":"published","doi":"10.1126/scitranslmed.aap8168","quality_controlled":"1","status":"public","day":"11","date_created":"2018-12-11T11:48:12Z","_id":"731","abstract":[{"text":"Genetic variations in the oxytocin receptor gene affect patients with ASD and ADHD differently.","lang":"eng"}],"scopus_import":1,"type":"journal_article","volume":9,"citation":{"mla":"Novarino, Gaia. “The Science of Love in ASD and ADHD.” <i>Science Translational Medicine</i>, vol. 9, no. 411, eaap8168, American Association for the Advancement of Science, 2017, doi:<a href=\"https://doi.org/10.1126/scitranslmed.aap8168\">10.1126/scitranslmed.aap8168</a>.","apa":"Novarino, G. (2017). The science of love in ASD and ADHD. <i>Science Translational Medicine</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/scitranslmed.aap8168\">https://doi.org/10.1126/scitranslmed.aap8168</a>","chicago":"Novarino, Gaia. “The Science of Love in ASD and ADHD.” <i>Science Translational Medicine</i>. American Association for the Advancement of Science, 2017. <a href=\"https://doi.org/10.1126/scitranslmed.aap8168\">https://doi.org/10.1126/scitranslmed.aap8168</a>.","ama":"Novarino G. The science of love in ASD and ADHD. <i>Science Translational Medicine</i>. 2017;9(411). doi:<a href=\"https://doi.org/10.1126/scitranslmed.aap8168\">10.1126/scitranslmed.aap8168</a>","ieee":"G. Novarino, “The science of love in ASD and ADHD,” <i>Science Translational Medicine</i>, vol. 9, no. 411. American Association for the Advancement of Science, 2017.","short":"G. Novarino, Science Translational Medicine 9 (2017).","ista":"Novarino G. 2017. The science of love in ASD and ADHD. Science Translational Medicine. 9(411), eaap8168."},"publication_identifier":{"issn":["19466234"]}},{"isi":1,"ec_funded":1,"oa_version":"Published Version","related_material":{"record":[{"id":"819","relation":"dissertation_contains","status":"public"}]},"doi":"10.1186/s12862-017-1062-4","publication":"BMC Evolutionary Biology","status":"public","day":"13","tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"ddc":["576","592"],"date_created":"2018-12-11T11:48:12Z","volume":17,"year":"2017","external_id":{"isi":["000412816800001"]},"issue":"1","oa":1,"date_updated":"2023-09-28T11:31:32Z","article_number":"219","month":"10","intvolume":"        17","date_published":"2017-10-13T00:00:00Z","publication_status":"published","project":[{"name":"Social Vaccination in Ant Colonies: from Individual Mechanisms to Society Effects","_id":"25DC711C-B435-11E9-9278-68D0E5697425","grant_number":"243071","call_identifier":"FP7"}],"quality_controlled":"1","_id":"732","type":"journal_article","file_date_updated":"2020-07-14T12:47:55Z","abstract":[{"text":"Background: Social insects form densely crowded societies in environments with high pathogen loads, but have evolved collective defences that mitigate the impact of disease. However, colony-founding queens lack this protection and suffer high rates of mortality. The impact of pathogens may be exacerbated in species where queens found colonies together, as healthy individuals may contract pathogens from infectious co-founders. Therefore, we tested whether ant queens avoid founding colonies with pathogen-exposed conspecifics and how they might limit disease transmission from infectious individuals. Results: Using Lasius Niger queens and a naturally infecting fungal pathogen Metarhizium brunneum, we observed that queens were equally likely to found colonies with another pathogen-exposed or sham-treated queen. However, when one queen died, the surviving individual performed biting, burial and removal of the corpse. These undertaking behaviours were performed prophylactically, i.e. targeted equally towards non-infected and infected corpses, as well as carried out before infected corpses became infectious. Biting and burial reduced the risk of the queens contracting and dying from disease from an infectious corpse of a dead co-foundress. Conclusions: We show that co-founding ant queens express undertaking behaviours that, in mature colonies, are performed exclusively by workers. Such infection avoidance behaviours act before the queens can contract the disease and will therefore improve the overall chance of colony founding success in ant queens.","lang":"eng"}],"scopus_import":"1","publication_identifier":{"issn":["14712148"]},"citation":{"chicago":"Pull, Christopher, and Sylvia Cremer. “Co-Founding Ant Queens Prevent Disease by Performing Prophylactic Undertaking Behaviour.” <i>BMC Evolutionary Biology</i>. BioMed Central, 2017. <a href=\"https://doi.org/10.1186/s12862-017-1062-4\">https://doi.org/10.1186/s12862-017-1062-4</a>.","ieee":"C. Pull and S. Cremer, “Co-founding ant queens prevent disease by performing prophylactic undertaking behaviour,” <i>BMC Evolutionary Biology</i>, vol. 17, no. 1. BioMed Central, 2017.","ista":"Pull C, Cremer S. 2017. Co-founding ant queens prevent disease by performing prophylactic undertaking behaviour. BMC Evolutionary Biology. 17(1), 219.","short":"C. Pull, S. Cremer, BMC Evolutionary Biology 17 (2017).","ama":"Pull C, Cremer S. Co-founding ant queens prevent disease by performing prophylactic undertaking behaviour. <i>BMC Evolutionary Biology</i>. 2017;17(1). doi:<a href=\"https://doi.org/10.1186/s12862-017-1062-4\">10.1186/s12862-017-1062-4</a>","mla":"Pull, Christopher, and Sylvia Cremer. “Co-Founding Ant Queens Prevent Disease by Performing Prophylactic Undertaking Behaviour.” <i>BMC Evolutionary Biology</i>, vol. 17, no. 1, 219, BioMed Central, 2017, doi:<a href=\"https://doi.org/10.1186/s12862-017-1062-4\">10.1186/s12862-017-1062-4</a>.","apa":"Pull, C., &#38; Cremer, S. (2017). Co-founding ant queens prevent disease by performing prophylactic undertaking behaviour. <i>BMC Evolutionary Biology</i>. BioMed Central. <a href=\"https://doi.org/10.1186/s12862-017-1062-4\">https://doi.org/10.1186/s12862-017-1062-4</a>"},"pubrep_id":"882","article_type":"original","language":[{"iso":"eng"}],"publist_id":"6937","department":[{"_id":"SyCr"}],"article_processing_charge":"Yes","file":[{"date_created":"2018-12-12T10:17:18Z","date_updated":"2020-07-14T12:47:55Z","file_name":"IST-2017-882-v1+1_12862_2017_Article_1062.pdf","relation":"main_file","checksum":"3e24a2cfd48f49f7b3643d08d30fb480","access_level":"open_access","content_type":"application/pdf","file_id":"5271","creator":"system","file_size":949857}],"author":[{"id":"3C7F4840-F248-11E8-B48F-1D18A9856A87","first_name":"Christopher","last_name":"Pull","orcid":"0000-0003-1122-3982","full_name":"Pull, Christopher"},{"full_name":"Cremer, Sylvia","id":"2F64EC8C-F248-11E8-B48F-1D18A9856A87","first_name":"Sylvia","last_name":"Cremer","orcid":"0000-0002-2193-3868"}],"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","title":"Co-founding ant queens prevent disease by performing prophylactic undertaking behaviour","publisher":"BioMed Central","has_accepted_license":"1"},{"date_created":"2018-12-11T11:48:13Z","day":"15","status":"public","volume":319,"isi":1,"oa_version":"Submitted Version","ec_funded":1,"doi":"10.1016/j.aim.2017.08.028","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1606.03076"}],"publication":"Advances in Mathematics","date_updated":"2023-09-28T11:30:42Z","oa":1,"month":"10","intvolume":"       319","date_published":"2017-10-15T00:00:00Z","acknowledgement":"Partially supported by ERC Advanced Grant RANMAT No. 338804, Hong Kong RGC grant ECS 26301517, and the Göran Gustafsson Foundation","year":"2017","page":"251 - 291","external_id":{"isi":["000412150400010"]},"_id":"733","quality_controlled":"1","citation":{"ama":"Bao Z, Erdös L, Schnelli K. Convergence rate for spectral distribution of addition of random matrices. <i>Advances in Mathematics</i>. 2017;319:251-291. doi:<a href=\"https://doi.org/10.1016/j.aim.2017.08.028\">10.1016/j.aim.2017.08.028</a>","short":"Z. Bao, L. Erdös, K. Schnelli, Advances in Mathematics 319 (2017) 251–291.","ieee":"Z. Bao, L. Erdös, and K. Schnelli, “Convergence rate for spectral distribution of addition of random matrices,” <i>Advances in Mathematics</i>, vol. 319. Academic Press, pp. 251–291, 2017.","ista":"Bao Z, Erdös L, Schnelli K. 2017. Convergence rate for spectral distribution of addition of random matrices. Advances in Mathematics. 319, 251–291.","chicago":"Bao, Zhigang, László Erdös, and Kevin Schnelli. “Convergence Rate for Spectral Distribution of Addition of Random Matrices.” <i>Advances in Mathematics</i>. Academic Press, 2017. <a href=\"https://doi.org/10.1016/j.aim.2017.08.028\">https://doi.org/10.1016/j.aim.2017.08.028</a>.","apa":"Bao, Z., Erdös, L., &#38; Schnelli, K. (2017). Convergence rate for spectral distribution of addition of random matrices. <i>Advances in Mathematics</i>. Academic Press. <a href=\"https://doi.org/10.1016/j.aim.2017.08.028\">https://doi.org/10.1016/j.aim.2017.08.028</a>","mla":"Bao, Zhigang, et al. “Convergence Rate for Spectral Distribution of Addition of Random Matrices.” <i>Advances in Mathematics</i>, vol. 319, Academic Press, 2017, pp. 251–91, doi:<a href=\"https://doi.org/10.1016/j.aim.2017.08.028\">10.1016/j.aim.2017.08.028</a>."},"type":"journal_article","abstract":[{"text":"Let A and B be two N by N deterministic Hermitian matrices and let U be an N by N Haar distributed unitary matrix. It is well known that the spectral distribution of the sum H = A + UBU∗ converges weakly to the free additive convolution of the spectral distributions of A and B, as N tends to infinity. We establish the optimal convergence rate in the bulk of the spectrum.","lang":"eng"}],"scopus_import":"1","project":[{"call_identifier":"FP7","grant_number":"338804","_id":"258DCDE6-B435-11E9-9278-68D0E5697425","name":"Random matrices, universality and disordered quantum systems"}],"publication_status":"published","title":"Convergence rate for spectral distribution of addition of random matrices","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","author":[{"full_name":"Bao, Zhigang","first_name":"Zhigang","id":"442E6A6C-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-3036-1475","last_name":"Bao"},{"last_name":"Erdös","orcid":"0000-0001-5366-9603","id":"4DBD5372-F248-11E8-B48F-1D18A9856A87","first_name":"László","full_name":"Erdös, László"},{"last_name":"Schnelli","orcid":"0000-0003-0954-3231","id":"434AD0AE-F248-11E8-B48F-1D18A9856A87","first_name":"Kevin","full_name":"Schnelli, Kevin"}],"publisher":"Academic Press","language":[{"iso":"eng"}],"article_processing_charge":"No","department":[{"_id":"LaEr"}],"publist_id":"6935"},{"oa_version":"Submitted Version","isi":1,"related_material":{"record":[{"status":"public","relation":"dissertation_contains","id":"819"}]},"publication":"Trends in Ecology and Evolution","doi":"10.1016/j.tree.2017.08.004","status":"public","day":"01","date_created":"2018-12-11T11:48:13Z","ddc":["570"],"volume":32,"year":"2017","page":"861 - 872","external_id":{"isi":["000413231900011"]},"oa":1,"issue":"11","date_updated":"2023-09-27T14:15:15Z","date_published":"2017-11-01T00:00:00Z","intvolume":"        32","month":"11","publication_status":"published","quality_controlled":"1","_id":"734","scopus_import":"1","abstract":[{"lang":"eng","text":"Social insect societies are long-standing models for understanding social behaviour and evolution. Unlike other advanced biological societies (such as the multicellular body), the component parts of social insect societies can be easily deconstructed and manipulated. Recent methodological and theoretical innovations have exploited this trait to address an expanded range of biological questions. We illustrate the broadening range of biological insight coming from social insect biology with four examples. These new frontiers promote open-minded, interdisciplinary exploration of one of the richest and most complex of biological phenomena: sociality."}],"file_date_updated":"2020-07-14T12:47:56Z","type":"journal_article","citation":{"ama":"Kennedy P, Baron G, Qiu B, et al. Deconstructing superorganisms and societies to address big questions in biology. <i>Trends in Ecology and Evolution</i>. 2017;32(11):861-872. doi:<a href=\"https://doi.org/10.1016/j.tree.2017.08.004\">10.1016/j.tree.2017.08.004</a>","short":"P. Kennedy, G. Baron, B. Qiu, D. Freitak, H. Helantera, E. Hunt, F. Manfredini, T. O’Shea Wheller, S. Patalano, C. Pull, T. Sasaki, D. Taylor, C. Wyatt, S. Sumner, Trends in Ecology and Evolution 32 (2017) 861–872.","ista":"Kennedy P, Baron G, Qiu B, Freitak D, Helantera H, Hunt E, Manfredini F, O’Shea Wheller T, Patalano S, Pull C, Sasaki T, Taylor D, Wyatt C, Sumner S. 2017. Deconstructing superorganisms and societies to address big questions in biology. Trends in Ecology and Evolution. 32(11), 861–872.","ieee":"P. Kennedy <i>et al.</i>, “Deconstructing superorganisms and societies to address big questions in biology,” <i>Trends in Ecology and Evolution</i>, vol. 32, no. 11. Cell Press, pp. 861–872, 2017.","chicago":"Kennedy, Patrick, Gemma Baron, Bitao Qiu, Dalial Freitak, Heikki Helantera, Edmund Hunt, Fabio Manfredini, et al. “Deconstructing Superorganisms and Societies to Address Big Questions in Biology.” <i>Trends in Ecology and Evolution</i>. Cell Press, 2017. <a href=\"https://doi.org/10.1016/j.tree.2017.08.004\">https://doi.org/10.1016/j.tree.2017.08.004</a>.","apa":"Kennedy, P., Baron, G., Qiu, B., Freitak, D., Helantera, H., Hunt, E., … Sumner, S. (2017). Deconstructing superorganisms and societies to address big questions in biology. <i>Trends in Ecology and Evolution</i>. Cell Press. <a href=\"https://doi.org/10.1016/j.tree.2017.08.004\">https://doi.org/10.1016/j.tree.2017.08.004</a>","mla":"Kennedy, Patrick, et al. “Deconstructing Superorganisms and Societies to Address Big Questions in Biology.” <i>Trends in Ecology and Evolution</i>, vol. 32, no. 11, Cell Press, 2017, pp. 861–72, doi:<a href=\"https://doi.org/10.1016/j.tree.2017.08.004\">10.1016/j.tree.2017.08.004</a>."},"publication_identifier":{"issn":["01695347"]},"article_type":"original","language":[{"iso":"eng"}],"publist_id":"6933","department":[{"_id":"SyCr"}],"article_processing_charge":"No","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","author":[{"first_name":"Patrick","last_name":"Kennedy","full_name":"Kennedy, Patrick"},{"full_name":"Baron, Gemma","first_name":"Gemma","last_name":"Baron"},{"full_name":"Qiu, Bitao","first_name":"Bitao","last_name":"Qiu"},{"last_name":"Freitak","first_name":"Dalial","full_name":"Freitak, Dalial"},{"last_name":"Helantera","first_name":"Heikki","full_name":"Helantera, Heikki"},{"full_name":"Hunt, Edmund","first_name":"Edmund","last_name":"Hunt"},{"first_name":"Fabio","last_name":"Manfredini","full_name":"Manfredini, Fabio"},{"full_name":"O'Shea Wheller, Thomas","first_name":"Thomas","last_name":"O'Shea Wheller"},{"first_name":"Solenn","last_name":"Patalano","full_name":"Patalano, Solenn"},{"first_name":"Christopher","id":"3C7F4840-F248-11E8-B48F-1D18A9856A87","last_name":"Pull","orcid":"0000-0003-1122-3982","full_name":"Pull, Christopher"},{"first_name":"Takao","last_name":"Sasaki","full_name":"Sasaki, Takao"},{"first_name":"Daisy","last_name":"Taylor","full_name":"Taylor, Daisy"},{"full_name":"Wyatt, Christopher","last_name":"Wyatt","first_name":"Christopher"},{"full_name":"Sumner, Seirian","first_name":"Seirian","last_name":"Sumner"}],"title":"Deconstructing superorganisms and societies to address big questions in biology","file":[{"relation":"main_file","checksum":"c8f49309ed9436201814fa7153d66a99","access_level":"open_access","content_type":"application/pdf","file_id":"7842","creator":"dernst","file_size":15018382,"date_created":"2020-05-14T16:22:27Z","date_updated":"2020-07-14T12:47:56Z","file_name":"2017_TrendsEcology_Kennedy.pdf"}],"publisher":"Cell Press","has_accepted_license":"1"},{"project":[{"name":"International IST Postdoc Fellowship Programme","_id":"25681D80-B435-11E9-9278-68D0E5697425","grant_number":"291734","call_identifier":"FP7"},{"grant_number":"I2058","call_identifier":"FWF","name":"Cell segregation in gastrulation: the role of cell fate specification","_id":"252DD2A6-B435-11E9-9278-68D0E5697425"}],"publication_status":"published","publication_identifier":{"issn":["15345807"]},"citation":{"apa":"Barone, V., Lang, M., Krens, G., Pradhan, S., Shamipour, S., Sako, K., … Heisenberg, C.-P. J. (2017). An effective feedback loop between cell-cell contact duration and morphogen signaling determines cell fate. <i>Developmental Cell</i>. Cell Press. <a href=\"https://doi.org/10.1016/j.devcel.2017.09.014\">https://doi.org/10.1016/j.devcel.2017.09.014</a>","mla":"Barone, Vanessa, et al. “An Effective Feedback Loop between Cell-Cell Contact Duration and Morphogen Signaling Determines Cell Fate.” <i>Developmental Cell</i>, vol. 43, no. 2, Cell Press, 2017, pp. 198–211, doi:<a href=\"https://doi.org/10.1016/j.devcel.2017.09.014\">10.1016/j.devcel.2017.09.014</a>.","ieee":"V. Barone <i>et al.</i>, “An effective feedback loop between cell-cell contact duration and morphogen signaling determines cell fate,” <i>Developmental Cell</i>, vol. 43, no. 2. Cell Press, pp. 198–211, 2017.","ista":"Barone V, Lang M, Krens G, Pradhan S, Shamipour S, Sako K, Sikora MK, Guet CC, Heisenberg C-PJ. 2017. An effective feedback loop between cell-cell contact duration and morphogen signaling determines cell fate. Developmental Cell. 43(2), 198–211.","short":"V. Barone, M. Lang, G. Krens, S. Pradhan, S. Shamipour, K. Sako, M.K. Sikora, C.C. Guet, C.-P.J. Heisenberg, Developmental Cell 43 (2017) 198–211.","ama":"Barone V, Lang M, Krens G, et al. An effective feedback loop between cell-cell contact duration and morphogen signaling determines cell fate. <i>Developmental Cell</i>. 2017;43(2):198-211. doi:<a href=\"https://doi.org/10.1016/j.devcel.2017.09.014\">10.1016/j.devcel.2017.09.014</a>","chicago":"Barone, Vanessa, Moritz Lang, Gabriel Krens, Saurabh Pradhan, Shayan Shamipour, Keisuke Sako, Mateusz K Sikora, Calin C Guet, and Carl-Philipp J Heisenberg. “An Effective Feedback Loop between Cell-Cell Contact Duration and Morphogen Signaling Determines Cell Fate.” <i>Developmental Cell</i>. Cell Press, 2017. <a href=\"https://doi.org/10.1016/j.devcel.2017.09.014\">https://doi.org/10.1016/j.devcel.2017.09.014</a>."},"type":"journal_article","scopus_import":"1","abstract":[{"text":"Cell-cell contact formation constitutes an essential step in evolution, leading to the differentiation of specialized cell types. However, remarkably little is known about whether and how the interplay between contact formation and fate specification affects development. Here, we identify a positive feedback loop between cell-cell contact duration, morphogen signaling, and mesendoderm cell-fate specification during zebrafish gastrulation. We show that long-lasting cell-cell contacts enhance the competence of prechordal plate (ppl) progenitor cells to respond to Nodal signaling, required for ppl cell-fate specification. We further show that Nodal signaling promotes ppl cell-cell contact duration, generating a positive feedback loop between ppl cell-cell contact duration and cell-fate specification. Finally, by combining mathematical modeling and experimentation, we show that this feedback determines whether anterior axial mesendoderm cells become ppl or, instead, turn into endoderm. Thus, the interdependent activities of cell-cell signaling and contact formation control fate diversification within the developing embryo.","lang":"eng"}],"_id":"735","quality_controlled":"1","article_processing_charge":"No","publist_id":"6934","department":[{"_id":"CaHe"},{"_id":"CaGu"},{"_id":"GaTk"}],"language":[{"iso":"eng"}],"publisher":"Cell Press","author":[{"full_name":"Barone, Vanessa","first_name":"Vanessa","id":"419EECCC-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-2676-3367","last_name":"Barone"},{"id":"29E0800A-F248-11E8-B48F-1D18A9856A87","first_name":"Moritz","last_name":"Lang","full_name":"Lang, Moritz"},{"full_name":"Krens, Gabriel","orcid":"0000-0003-4761-5996","last_name":"Krens","first_name":"Gabriel","id":"2B819732-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Saurabh","last_name":"Pradhan","full_name":"Pradhan, Saurabh"},{"last_name":"Shamipour","id":"40B34FE2-F248-11E8-B48F-1D18A9856A87","first_name":"Shayan","full_name":"Shamipour, Shayan"},{"full_name":"Sako, Keisuke","orcid":"0000-0002-6453-8075","last_name":"Sako","id":"3BED66BE-F248-11E8-B48F-1D18A9856A87","first_name":"Keisuke"},{"id":"2F74BCDE-F248-11E8-B48F-1D18A9856A87","first_name":"Mateusz K","last_name":"Sikora","full_name":"Sikora, Mateusz K"},{"first_name":"Calin C","id":"47F8433E-F248-11E8-B48F-1D18A9856A87","last_name":"Guet","orcid":"0000-0001-6220-2052","full_name":"Guet, Calin C"},{"orcid":"0000-0002-0912-4566","last_name":"Heisenberg","id":"39427864-F248-11E8-B48F-1D18A9856A87","first_name":"Carl-Philipp J","full_name":"Heisenberg, Carl-Philipp J"}],"title":"An effective feedback loop between cell-cell contact duration and morphogen signaling determines cell fate","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","doi":"10.1016/j.devcel.2017.09.014","publication":"Developmental Cell","related_material":{"record":[{"id":"961","relation":"dissertation_contains","status":"public"},{"status":"public","relation":"dissertation_contains","id":"8350"}]},"isi":1,"oa_version":"None","ec_funded":1,"volume":43,"date_created":"2018-12-11T11:48:13Z","day":"23","status":"public","external_id":{"isi":["000413443700011"]},"page":"198 - 211","year":"2017","month":"10","intvolume":"        43","date_published":"2017-10-23T00:00:00Z","date_updated":"2024-03-25T23:30:21Z","issue":"2"},{"doi":"10.1007/s00429-017-1408-0","publication":"Brain Structure and Function","isi":1,"oa_version":"Published Version","volume":222,"ddc":["571"],"tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"date_created":"2018-12-11T11:48:14Z","day":"01","status":"public","external_id":{"isi":["000414761700002"]},"page":"3375 - 3393","year":"2017","month":"11","intvolume":"       222","date_published":"2017-11-01T00:00:00Z","date_updated":"2023-09-27T14:14:51Z","issue":"8","oa":1,"publication_status":"published","publication_identifier":{"issn":["18632653"]},"citation":{"chicago":"Rubio, María, Ko Matsui, Yugo Fukazawa, Naomi Kamasawa, Harumi Harada, Makoto Itakura, Elek Molnár, Manabu Abe, Kenji Sakimura, and Ryuichi Shigemoto. “The Number and Distribution of AMPA Receptor Channels Containing Fast Kinetic GluA3 and GluA4 Subunits at Auditory Nerve Synapses Depend on the Target Cells.” <i>Brain Structure and Function</i>. Springer, 2017. <a href=\"https://doi.org/10.1007/s00429-017-1408-0\">https://doi.org/10.1007/s00429-017-1408-0</a>.","ama":"Rubio M, Matsui K, Fukazawa Y, et al. The number and distribution of AMPA receptor channels containing fast kinetic GluA3 and GluA4 subunits at auditory nerve synapses depend on the target cells. <i>Brain Structure and Function</i>. 2017;222(8):3375-3393. doi:<a href=\"https://doi.org/10.1007/s00429-017-1408-0\">10.1007/s00429-017-1408-0</a>","short":"M. Rubio, K. Matsui, Y. Fukazawa, N. Kamasawa, H. Harada, M. Itakura, E. Molnár, M. Abe, K. Sakimura, R. Shigemoto, Brain Structure and Function 222 (2017) 3375–3393.","ista":"Rubio M, Matsui K, Fukazawa Y, Kamasawa N, Harada H, Itakura M, Molnár E, Abe M, Sakimura K, Shigemoto R. 2017. The number and distribution of AMPA receptor channels containing fast kinetic GluA3 and GluA4 subunits at auditory nerve synapses depend on the target cells. Brain Structure and Function. 222(8), 3375–3393.","ieee":"M. Rubio <i>et al.</i>, “The number and distribution of AMPA receptor channels containing fast kinetic GluA3 and GluA4 subunits at auditory nerve synapses depend on the target cells,” <i>Brain Structure and Function</i>, vol. 222, no. 8. Springer, pp. 3375–3393, 2017.","mla":"Rubio, María, et al. “The Number and Distribution of AMPA Receptor Channels Containing Fast Kinetic GluA3 and GluA4 Subunits at Auditory Nerve Synapses Depend on the Target Cells.” <i>Brain Structure and Function</i>, vol. 222, no. 8, Springer, 2017, pp. 3375–93, doi:<a href=\"https://doi.org/10.1007/s00429-017-1408-0\">10.1007/s00429-017-1408-0</a>.","apa":"Rubio, M., Matsui, K., Fukazawa, Y., Kamasawa, N., Harada, H., Itakura, M., … Shigemoto, R. (2017). The number and distribution of AMPA receptor channels containing fast kinetic GluA3 and GluA4 subunits at auditory nerve synapses depend on the target cells. <i>Brain Structure and Function</i>. Springer. <a href=\"https://doi.org/10.1007/s00429-017-1408-0\">https://doi.org/10.1007/s00429-017-1408-0</a>"},"file_date_updated":"2020-07-14T12:47:56Z","type":"journal_article","abstract":[{"lang":"eng","text":"The neurotransmitter receptor subtype, number, density, and distribution relative to the location of transmitter release sites are key determinants of signal transmission. AMPA-type ionotropic glutamate receptors (AMPARs) containing GluA3 and GluA4 subunits are prominently expressed in subsets of neurons capable of firing action potentials at high frequencies, such as auditory relay neurons. The auditory nerve (AN) forms glutamatergic synapses on two types of relay neurons, bushy cells (BCs) and fusiform cells (FCs) of the cochlear nucleus. AN-BC and AN-FC synapses have distinct kinetics; thus, we investigated whether the number, density, and localization of GluA3 and GluA4 subunits in these synapses are differentially organized using quantitative freeze-fracture replica immunogold labeling. We identify a positive correlation between the number of AMPARs and the size of AN-BC and AN-FC synapses. Both types of AN synapses have similar numbers of AMPARs; however, the AN-BC have a higher density of AMPARs than AN-FC synapses, because the AN-BC synapses are smaller. A higher number and density of GluA3 subunits are observed at AN-BC synapses, whereas a higher number and density of GluA4 subunits are observed at AN-FC synapses. The intrasynaptic distribution of immunogold labeling revealed that AMPAR subunits, particularly GluA3, are concentrated at the center of the AN-BC synapses. The central distribution of AMPARs is absent in GluA3-knockout mice, and gold particles are evenly distributed along the postsynaptic density. GluA4 gold labeling was homogenously distributed along both synapse types. Thus, GluA3 and GluA4 subunits are distributed at AN synapses in a target-cell-dependent manner."}],"scopus_import":"1","_id":"736","quality_controlled":"1","article_processing_charge":"No","department":[{"_id":"RySh"}],"publist_id":"6932","language":[{"iso":"eng"}],"pubrep_id":"881","has_accepted_license":"1","publisher":"Springer","file":[{"date_updated":"2020-07-14T12:47:56Z","date_created":"2018-12-12T10:10:20Z","file_name":"IST-2017-881-v1+1_s00429-017-1408-0.pdf","relation":"main_file","checksum":"73787a22507de8fb585bb598e1418ca7","access_level":"open_access","file_size":4011126,"creator":"system","content_type":"application/pdf","file_id":"4806"}],"title":"The number and distribution of AMPA receptor channels containing fast kinetic GluA3 and GluA4 subunits at auditory nerve synapses depend on the target cells","author":[{"last_name":"Rubio","first_name":"María","full_name":"Rubio, María"},{"full_name":"Matsui, Ko","last_name":"Matsui","first_name":"Ko"},{"first_name":"Yugo","last_name":"Fukazawa","full_name":"Fukazawa, Yugo"},{"full_name":"Kamasawa, Naomi","last_name":"Kamasawa","first_name":"Naomi"},{"full_name":"Harada, Harumi","orcid":"0000-0001-7429-7896","last_name":"Harada","first_name":"Harumi","id":"2E55CDF2-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Itakura","first_name":"Makoto","full_name":"Itakura, Makoto"},{"full_name":"Molnár, Elek","last_name":"Molnár","first_name":"Elek"},{"full_name":"Abe, Manabu","first_name":"Manabu","last_name":"Abe"},{"first_name":"Kenji","last_name":"Sakimura","full_name":"Sakimura, Kenji"},{"full_name":"Shigemoto, Ryuichi","last_name":"Shigemoto","orcid":"0000-0001-8761-9444","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","first_name":"Ryuichi"}],"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1"}]