[{"date_updated":"2021-01-12T08:21:59Z","type":"journal_article","oa_version":"Preprint","day":"08","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","language":[{"iso":"eng"}],"doi":"10.1063/1.5000973","date_published":"2017-09-08T00:00:00Z","external_id":{"pmid":["28964202"],"arxiv":["1703.06470"]},"arxiv":1,"year":"2017","citation":{"ieee":"T. Menke <i>et al.</i>, “Reconfigurable re-entrant cavity for wireless coupling to an electro-optomechanical device,” <i>Review of Scientific Instruments</i>, vol. 88, no. 9. American Institute of Physics, 2017.","ama":"Menke T, Burns P, Higginbotham AP, et al. Reconfigurable re-entrant cavity for wireless coupling to an electro-optomechanical device. <i>Review of Scientific Instruments</i>. 2017;88(9). doi:<a href=\"https://doi.org/10.1063/1.5000973\">10.1063/1.5000973</a>","ista":"Menke T, Burns P, Higginbotham AP, Kampel NS, Peterson R, Cicak K, Simmonds R, Regal C, Lehnert K. 2017. Reconfigurable re-entrant cavity for wireless coupling to an electro-optomechanical device. Review of Scientific Instruments. 88(9), 094701.","short":"T. Menke, P. Burns, A.P. Higginbotham, N.S. Kampel, R. Peterson, K. Cicak, R. Simmonds, C. Regal, K. Lehnert, Review of Scientific Instruments 88 (2017).","chicago":"Menke, Tim, Peter Burns, Andrew P Higginbotham, N S Kampel, Robert Peterson, Katarina Cicak, Raymond Simmonds, Cindy Regal, and Konrad Lehnert. “Reconfigurable Re-Entrant Cavity for Wireless Coupling to an Electro-Optomechanical Device.” <i>Review of Scientific Instruments</i>. American Institute of Physics, 2017. <a href=\"https://doi.org/10.1063/1.5000973\">https://doi.org/10.1063/1.5000973</a>.","mla":"Menke, Tim, et al. “Reconfigurable Re-Entrant Cavity for Wireless Coupling to an Electro-Optomechanical Device.” <i>Review of Scientific Instruments</i>, vol. 88, no. 9, 094701, American Institute of Physics, 2017, doi:<a href=\"https://doi.org/10.1063/1.5000973\">10.1063/1.5000973</a>.","apa":"Menke, T., Burns, P., Higginbotham, A. P., Kampel, N. S., Peterson, R., Cicak, K., … Lehnert, K. (2017). Reconfigurable re-entrant cavity for wireless coupling to an electro-optomechanical device. <i>Review of Scientific Instruments</i>. American Institute of Physics. <a href=\"https://doi.org/10.1063/1.5000973\">https://doi.org/10.1063/1.5000973</a>"},"main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1703.06470"}],"quality_controlled":"1","author":[{"full_name":"Menke, Tim","first_name":"Tim","last_name":"Menke"},{"full_name":"Burns, Peter","last_name":"Burns","first_name":"Peter"},{"last_name":"Higginbotham","first_name":"Andrew P","full_name":"Higginbotham, Andrew P","orcid":"0000-0003-2607-2363","id":"4AD6785A-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Kampel","first_name":"N S","full_name":"Kampel, N S"},{"last_name":"Peterson","first_name":"Robert","full_name":"Peterson, Robert"},{"first_name":"Katarina","last_name":"Cicak","full_name":"Cicak, Katarina"},{"full_name":"Simmonds, Raymond","first_name":"Raymond","last_name":"Simmonds"},{"full_name":"Regal, Cindy","first_name":"Cindy","last_name":"Regal"},{"full_name":"Lehnert, Konrad","last_name":"Lehnert","first_name":"Konrad"}],"extern":"1","publication_status":"published","abstract":[{"text":"An electro-optomechanical device capable of microwave-to-optics conversion has recently been demonstrated, with the vision of enabling optical networks of superconducting qubits. Here we present an improved converter design that uses a three-dimensional microwave cavity for coupling between the microwave transmission line and an integrated LC resonator on the converter chip. The new design simplifies the optical assembly and decouples it from the microwave part of the setup. Experimental demonstrations show that the modular device assembly allows us to flexibly tune the microwave coupling to the converter chip while maintaining small loss. We also find that electromechanical experiments are not impacted by the additional microwave cavity. Our design is compatible with a high-finesse optical cavity and will improve optical performance.","lang":"eng"}],"title":"Reconfigurable re-entrant cavity for wireless coupling to an electro-optomechanical device","publication":"Review of Scientific Instruments","pmid":1,"oa":1,"_id":"93","publisher":"American Institute of Physics","volume":88,"issue":"9","date_created":"2018-12-11T11:44:35Z","month":"09","status":"public","article_number":"094701","intvolume":"        88","publist_id":"7961"},{"oa_version":"None","type":"journal_article","date_updated":"2021-01-12T08:22:01Z","year":"2017","day":"16","citation":{"apa":"Scheele, C., Hannezo, E. B., Muraro, M., Zomer, A., Langedijk, N., Van Oudenaarden, A., … Van Rheenen, J. (2017). Identity and dynamics of mammary stem cells during branching morphogenesis. <i>Nature</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/nature21046\">https://doi.org/10.1038/nature21046</a>","mla":"Scheele, Colinda, et al. “Identity and Dynamics of Mammary Stem Cells during Branching Morphogenesis.” <i>Nature</i>, vol. 542, no. 7641, Nature Publishing Group, 2017, pp. 313–17, doi:<a href=\"https://doi.org/10.1038/nature21046\">10.1038/nature21046</a>.","ieee":"C. Scheele <i>et al.</i>, “Identity and dynamics of mammary stem cells during branching morphogenesis,” <i>Nature</i>, vol. 542, no. 7641. Nature Publishing Group, pp. 313–317, 2017.","ama":"Scheele C, Hannezo EB, Muraro M, et al. Identity and dynamics of mammary stem cells during branching morphogenesis. <i>Nature</i>. 2017;542(7641):313-317. doi:<a href=\"https://doi.org/10.1038/nature21046\">10.1038/nature21046</a>","short":"C. Scheele, E.B. Hannezo, M. Muraro, A. Zomer, N. Langedijk, A. Van Oudenaarden, B. Simons, J. Van Rheenen, Nature 542 (2017) 313–317.","chicago":"Scheele, Colinda, Edouard B Hannezo, Mauro Muraro, Anoek Zomer, Nathalia Langedijk, Alexander Van Oudenaarden, Benjamin Simons, and Jacco Van Rheenen. “Identity and Dynamics of Mammary Stem Cells during Branching Morphogenesis.” <i>Nature</i>. Nature Publishing Group, 2017. <a href=\"https://doi.org/10.1038/nature21046\">https://doi.org/10.1038/nature21046</a>.","ista":"Scheele C, Hannezo EB, Muraro M, Zomer A, Langedijk N, Van Oudenaarden A, Simons B, Van Rheenen J. 2017. Identity and dynamics of mammary stem cells during branching morphogenesis. Nature. 542(7641), 313–317."},"user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","quality_controlled":"1","extern":"1","author":[{"first_name":"Colinda","last_name":"Scheele","full_name":"Scheele, Colinda"},{"first_name":"Edouard B","last_name":"Hannezo","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","full_name":"Hannezo, Edouard B","orcid":"0000-0001-6005-1561"},{"full_name":"Muraro, Mauro","last_name":"Muraro","first_name":"Mauro"},{"last_name":"Zomer","first_name":"Anoek","full_name":"Zomer, Anoek"},{"last_name":"Langedijk","first_name":"Nathalia","full_name":"Langedijk, Nathalia"},{"full_name":"Van Oudenaarden, Alexander","first_name":"Alexander","last_name":"Van Oudenaarden"},{"full_name":"Simons, Benjamin","first_name":"Benjamin","last_name":"Simons"},{"last_name":"Van Rheenen","first_name":"Jacco","full_name":"Van Rheenen, Jacco"}],"abstract":[{"lang":"eng","text":"During puberty, the mouse mammary gland develops into a highly branched epithelial network. Owing to the absence of exclusive stem cell markers, the location, multiplicity, dynamics and fate of mammary stem cells (MaSCs), which drive branching morphogenesis, are unknown. Here we show that morphogenesis is driven by proliferative terminal end buds that terminate or bifurcate with near equal probability, in a stochastic and time-invariant manner, leading to a heterogeneous epithelial network. We show that the majority of terminal end bud cells function as highly proliferative, lineage-committed MaSCs that are heterogeneous in their expression profile and short-term contribution to ductal extension. Yet, through cell rearrangements during terminal end bud bifurcation, each MaSC is able to contribute actively to long-term growth. Our study shows that the behaviour of MaSCs is not directly linked to a single expression profile. Instead, morphogenesis relies upon lineage-restricted heterogeneous MaSC populations that function as single equipotent pools in the long term."}],"publication_status":"published","title":"Identity and dynamics of mammary stem cells during branching morphogenesis","publication":"Nature","_id":"934","language":[{"iso":"eng"}],"doi":"10.1038/nature21046","publisher":"Nature Publishing Group","date_published":"2017-02-16T00:00:00Z","page":"313 - 317","volume":542,"issue":"7641","month":"02","date_created":"2018-12-11T11:49:17Z","status":"public","intvolume":"       542","publist_id":"6505","publication_identifier":{"issn":["00280836"]}},{"publisher":"Company of Biologists","date_published":"2017-01-01T00:00:00Z","volume":130,"issue":"5","date_created":"2018-12-11T11:49:17Z","month":"01","status":"public","intvolume":"       130","publist_id":"6507","type":"journal_article","date_updated":"2021-01-12T08:22:02Z","oa_version":"None","day":"01","year":"2017","citation":{"mla":"Sedzinski, Jakub, et al. “RhoA Regulates Actin Network Dynamics during Apical Surface Emergence in Multiciliated Epithelial Cells .” <i>Journal of Cell Science</i>, vol. 130, no. 5, Company of Biologists, 2017, doi:<a href=\"https://doi.org/10.1242/jcs.202234\">10.1242/jcs.202234</a>.","apa":"Sedzinski, J., Hannezo, E. B., Tu, F., Biro, M., &#38; Wallingford, J. (2017). RhoA regulates actin network dynamics during apical surface emergence in multiciliated epithelial cells . <i>Journal of Cell Science</i>. Company of Biologists. <a href=\"https://doi.org/10.1242/jcs.202234\">https://doi.org/10.1242/jcs.202234</a>","ieee":"J. Sedzinski, E. B. Hannezo, F. Tu, M. Biro, and J. Wallingford, “RhoA regulates actin network dynamics during apical surface emergence in multiciliated epithelial cells ,” <i>Journal of Cell Science</i>, vol. 130, no. 5. Company of Biologists, 2017.","ama":"Sedzinski J, Hannezo EB, Tu F, Biro M, Wallingford J. RhoA regulates actin network dynamics during apical surface emergence in multiciliated epithelial cells . <i>Journal of Cell Science</i>. 2017;130(5). doi:<a href=\"https://doi.org/10.1242/jcs.202234\">10.1242/jcs.202234</a>","ista":"Sedzinski J, Hannezo EB, Tu F, Biro M, Wallingford J. 2017. RhoA regulates actin network dynamics during apical surface emergence in multiciliated epithelial cells . Journal of Cell Science. 130(5).","chicago":"Sedzinski, Jakub, Edouard B Hannezo, Fan Tu, Maté Biro, and John Wallingford. “RhoA Regulates Actin Network Dynamics during Apical Surface Emergence in Multiciliated Epithelial Cells .” <i>Journal of Cell Science</i>. Company of Biologists, 2017. <a href=\"https://doi.org/10.1242/jcs.202234\">https://doi.org/10.1242/jcs.202234</a>.","short":"J. Sedzinski, E.B. Hannezo, F. Tu, M. Biro, J. Wallingford, Journal of Cell Science 130 (2017)."},"extern":"1","author":[{"first_name":"Jakub","last_name":"Sedzinski","full_name":"Sedzinski, Jakub"},{"first_name":"Edouard B","last_name":"Hannezo","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","full_name":"Hannezo, Edouard B","orcid":"0000-0001-6005-1561"},{"full_name":"Tu, Fan","first_name":"Fan","last_name":"Tu"},{"full_name":"Biro, Maté","first_name":"Maté","last_name":"Biro"},{"first_name":"John","last_name":"Wallingford","full_name":"Wallingford, John"}],"quality_controlled":"1","user_id":"4435EBFC-F248-11E8-B48F-1D18A9856A87","publication_status":"published","abstract":[{"text":"Homeostatic replacement of epithelial cells from basal precursors is a multistep process involving progenitor cell specification, radial intercalation and, finally, apical surface emergence. Recent data demonstrate that actin-based pushing under the control of the formin protein Fmn1 drives apical emergence in nascent multiciliated epithelial cells (MCCs), but little else is known about this actin network or the control of Fmn1. Here, we explore the role of the small GTPase RhoA in MCC apical emergence. Disruption of RhoA function reduced the rate of apical surface expansion and decreased the final size of the apical domain. Analysis of cell shapes suggests that RhoA alters the balance of forces exerted on the MCC apical surface. Finally, quantitative time-lapse imaging and fluorescence recovery after photobleaching studies argue that RhoA works in concert with Fmn1 to control assembly of the specialized apical actin network in MCCs. These data provide new molecular insights into epithelial apical surface assembly and could also shed light on mechanisms of apical lumen formation","lang":"eng"}],"publication":"Journal of Cell Science","title":"RhoA regulates actin network dynamics during apical surface emergence in multiciliated epithelial cells ","doi":"10.1242/jcs.202234","language":[{"iso":"eng"}],"_id":"936"},{"quality_controlled":"1","author":[{"full_name":"Pinheiro, Diana","last_name":"Pinheiro","first_name":"Diana"},{"full_name":"Hannezo, Edouard B","orcid":"0000-0001-6005-1561","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","first_name":"Edouard B","last_name":"Hannezo"},{"full_name":"Herszterg, Sophie","last_name":"Herszterg","first_name":"Sophie"},{"full_name":"Bosveld, Floris","last_name":"Bosveld","first_name":"Floris"},{"full_name":"Gaugué, Isabelle","first_name":"Isabelle","last_name":"Gaugué"},{"last_name":"Balakireva","first_name":"Maria","full_name":"Balakireva, Maria"},{"full_name":"Wang, Zhimin","last_name":"Wang","first_name":"Zhimin"},{"first_name":"Inês","last_name":"Cristo","full_name":"Cristo, Inês"},{"first_name":"Stéphane","last_name":"Rigaud","full_name":"Rigaud, Stéphane"},{"full_name":"Markova, Olga","first_name":"Olga","last_name":"Markova"},{"last_name":"Bellaïche","first_name":"Yohanns","full_name":"Bellaïche, Yohanns"}],"user_id":"4435EBFC-F248-11E8-B48F-1D18A9856A87","extern":"1","citation":{"apa":"Pinheiro, D., Hannezo, E. B., Herszterg, S., Bosveld, F., Gaugué, I., Balakireva, M., … Bellaïche, Y. (2017). Transmission of cytokinesis forces via E cadherin dilution and actomyosin flows. <i>Nature</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/nature22041\">https://doi.org/10.1038/nature22041</a>","mla":"Pinheiro, Diana, et al. “Transmission of Cytokinesis Forces via E Cadherin Dilution and Actomyosin Flows.” <i>Nature</i>, vol. 545, no. 7652, Nature Publishing Group, 2017, pp. 103–07, doi:<a href=\"https://doi.org/10.1038/nature22041\">10.1038/nature22041</a>.","ista":"Pinheiro D, Hannezo EB, Herszterg S, Bosveld F, Gaugué I, Balakireva M, Wang Z, Cristo I, Rigaud S, Markova O, Bellaïche Y. 2017. Transmission of cytokinesis forces via E cadherin dilution and actomyosin flows. Nature. 545(7652), 103–107.","short":"D. Pinheiro, E.B. Hannezo, S. Herszterg, F. Bosveld, I. Gaugué, M. Balakireva, Z. Wang, I. Cristo, S. Rigaud, O. Markova, Y. Bellaïche, Nature 545 (2017) 103–107.","chicago":"Pinheiro, Diana, Edouard B Hannezo, Sophie Herszterg, Floris Bosveld, Isabelle Gaugué, Maria Balakireva, Zhimin Wang, et al. “Transmission of Cytokinesis Forces via E Cadherin Dilution and Actomyosin Flows.” <i>Nature</i>. Nature Publishing Group, 2017. <a href=\"https://doi.org/10.1038/nature22041\">https://doi.org/10.1038/nature22041</a>.","ama":"Pinheiro D, Hannezo EB, Herszterg S, et al. Transmission of cytokinesis forces via E cadherin dilution and actomyosin flows. <i>Nature</i>. 2017;545(7652):103-107. doi:<a href=\"https://doi.org/10.1038/nature22041\">10.1038/nature22041</a>","ieee":"D. Pinheiro <i>et al.</i>, “Transmission of cytokinesis forces via E cadherin dilution and actomyosin flows,” <i>Nature</i>, vol. 545, no. 7652. Nature Publishing Group, pp. 103–107, 2017."},"year":"2017","day":"04","oa_version":"None","type":"journal_article","date_updated":"2021-01-12T08:22:02Z","_id":"937","doi":"10.1038/nature22041","language":[{"iso":"eng"}],"title":"Transmission of cytokinesis forces via E cadherin dilution and actomyosin flows","publication":"Nature","abstract":[{"lang":"eng","text":"During epithelial cytokinesis, the remodelling of adhesive cell-cell contacts between the dividing cell and its neighbours has profound implications for the integrity, arrangement and morphogenesis of proliferative tissues. In both vertebrates and invertebrates, this remodelling requires the activity of non-muscle myosin II (MyoII) in the interphasic cells neighbouring the dividing cell. However, the mechanisms that coordinate cytokinesis and MyoII activity in the neighbours are unknown. Here we show that in the Drosophila notum epithelium, each cell division is associated with a mechanosensing and transmission event that controls MyoII dynamics in neighbouring cells. We find that the ring pulling forces promote local junction elongation, which results in local E-cadherin dilution at the ingressing adherens junction. In turn, the reduction in E-cadherin concentration and the contractility of the neighbouring cells promote self-organized actomyosin flows, ultimately leading to accumulation of MyoII at the base of the ingressing junction. Although force transduction has been extensively studied in the context of adherens junction reinforcement to stabilize adhesive cell-cell contacts, we propose an alternative mechanosensing mechanism that coordinates actomyosin dynamics between epithelial cells and sustains the remodelling of the adherens junction in response to mechanical forces."}],"publication_status":"published","issue":"7652","volume":545,"page":"103 - 107","date_published":"2017-05-04T00:00:00Z","publisher":"Nature Publishing Group","publist_id":"6504","publication_identifier":{"issn":["00280836"]},"intvolume":"       545","status":"public","month":"05","date_created":"2018-12-11T11:49:18Z"},{"title":"Investigations into cell polarity and trafficking in the plant model Arabidopsis thaliana ","ddc":["581","583","580"],"related_material":{"record":[{"id":"1591","status":"public","relation":"part_of_dissertation"}]},"oa":1,"_id":"938","publication_status":"published","abstract":[{"text":"The thesis encompasses several topics of plant cell biology which were studied in the model plant Arabidopsis thaliana. Chapter 1 concerns the plant hormone auxin and its polar transport through cells and tissues. The highly controlled, directional transport of auxin is facilitated by plasma membrane-localized transporters. Transporters from the PIN family direct auxin transport due to their polarized localizations at cell membranes. Substantial effort has been put into research on cellular trafficking of PIN proteins, which is thought to underlie their polar distribution. I participated in a forward genetic screen aimed at identifying novel regulators of PIN polarity. The screen yielded several genes which may be involved in PIN polarity regulation or participate in polar auxin transport by other means. Chapter 2 focuses on the endomembrane system, with particular attention to clathrin-mediated endocytosis. The project started with identification of several proteins that interact with clathrin light chains. Among them, I focused on two putative homologues of auxilin, which in non-plant systems is an endocytotic factor known for uncoating clathrin-coated vesicles in the final step of endocytosis. The body of my work consisted of an in-depth characterization of transgenic A. thaliana lines overexpressing these putative auxilins in an inducible manner. Overexpression of these proteins leads to an inhibition of endocytosis, as documented by imaging of cargoes and clathrin-related endocytic machinery. An extension of this work is an investigation into a concept of homeostatic regulation acting between distinct transport processes in the endomembrane system. With auxilin overexpressing lines, where endocytosis is blocked specifically, I made observations on the mutual relationship between two opposite trafficking processes of secretion and endocytosis. In Chapter 3, I analyze cortical microtubule arrays and their relationship to auxin signaling and polarized growth in elongating cells. In plants, microtubules are organized into arrays just below the plasma membrane, and it is thought that their function is to guide membrane-docked cellulose synthase complexes. These, in turn, influence cell wall structure and cell shape by directed deposition of cellulose fibres. In elongating cells, cortical microtubule arrays are able to reorient in relation to long cell axis, and these reorientations have been linked to cell growth and to signaling of growth-regulating factors such as auxin or light. In this chapter, I am addressing the causal relationship between microtubule array reorientation, growth, and auxin signaling. I arrive at a model where array reorientation is not guided by auxin directly, but instead is only controlled by growth, which, in turn, is regulated by auxin.","lang":"eng"}],"citation":{"mla":"Adamowski, Maciek. <i>Investigations into Cell Polarity and Trafficking in the Plant Model Arabidopsis Thaliana </i>. Institute of Science and Technology Austria, 2017, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:th_842\">10.15479/AT:ISTA:th_842</a>.","apa":"Adamowski, M. (2017). <i>Investigations into cell polarity and trafficking in the plant model Arabidopsis thaliana </i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:th_842\">https://doi.org/10.15479/AT:ISTA:th_842</a>","ama":"Adamowski M. Investigations into cell polarity and trafficking in the plant model Arabidopsis thaliana . 2017. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:th_842\">10.15479/AT:ISTA:th_842</a>","ieee":"M. Adamowski, “Investigations into cell polarity and trafficking in the plant model Arabidopsis thaliana ,” Institute of Science and Technology Austria, 2017.","chicago":"Adamowski, Maciek. “Investigations into Cell Polarity and Trafficking in the Plant Model Arabidopsis Thaliana .” Institute of Science and Technology Austria, 2017. <a href=\"https://doi.org/10.15479/AT:ISTA:th_842\">https://doi.org/10.15479/AT:ISTA:th_842</a>.","short":"M. Adamowski, Investigations into Cell Polarity and Trafficking in the Plant Model Arabidopsis Thaliana , Institute of Science and Technology Austria, 2017.","ista":"Adamowski M. 2017. Investigations into cell polarity and trafficking in the plant model Arabidopsis thaliana . Institute of Science and Technology Austria."},"author":[{"last_name":"Adamowski","first_name":"Maciek","full_name":"Adamowski, Maciek","orcid":"0000-0001-6463-5257","id":"45F536D2-F248-11E8-B48F-1D18A9856A87"}],"year":"2017","publist_id":"6483","degree_awarded":"PhD","date_created":"2018-12-11T11:49:18Z","month":"06","status":"public","pubrep_id":"842","file_date_updated":"2020-07-14T12:48:15Z","publisher":"Institute of Science and Technology Austria","language":[{"iso":"eng"}],"doi":"10.15479/AT:ISTA:th_842","department":[{"_id":"JiFr"}],"has_accepted_license":"1","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","article_processing_charge":"No","date_updated":"2023-09-07T12:06:09Z","type":"dissertation","oa_version":"Published Version","day":"02","supervisor":[{"orcid":"0000-0002-8302-7596","full_name":"Friml, Jiří","id":"4159519E-F248-11E8-B48F-1D18A9856A87","last_name":"Friml","first_name":"Jiří"}],"alternative_title":["ISTA Thesis"],"publication_identifier":{"issn":["2663-337X"]},"date_published":"2017-06-02T00:00:00Z","file":[{"access_level":"closed","file_name":"2017_Adamowski-Thesis_Source.docx","checksum":"193425764d9aaaed3ac57062a867b315","file_id":"6215","date_updated":"2020-07-14T12:48:15Z","file_size":46903863,"creator":"dernst","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","date_created":"2019-04-05T09:03:20Z","relation":"source_file"},{"access_level":"open_access","checksum":"df5ab01be81f821e1b958596a1ec8d21","file_name":"2017_Adamowski-Thesis.pdf","date_updated":"2020-07-14T12:48:15Z","file_id":"6216","file_size":8698888,"creator":"dernst","content_type":"application/pdf","date_created":"2019-04-05T09:03:19Z","relation":"main_file"}],"page":"117"},{"abstract":[{"lang":"eng","text":"We reveal the existence of continuous families of guided single-mode solitons in planar waveguides with weakly nonlinear active core and absorbing boundaries. Stable propagation of TE and TM-polarized solitons is accompanied by attenuation of all other modes, i.e., the waveguide features properties of conservative and dissipative systems. If the linear spectrum of the waveguide possesses exceptional points, which occurs in the case of TM polarization, an originally focusing (defocusing) material nonlinearity may become effectively defocusing (focusing). This occurs due to the geometric phase of the carried eigenmode when the surface impedance encircles the exceptional point. In its turn, the change of the effective nonlinearity ensures the existence of dark (bright) solitons in spite of focusing (defocusing) Kerr nonlinearity of the core. The existence of an exceptional point can also result in anomalous enhancement of the effective nonlinearity. In terms of practical applications, the nonlinearity of the reported waveguide can be manipulated by controlling the properties of the absorbing cladding."}],"publication_status":"published","project":[{"call_identifier":"FP7","_id":"25681D80-B435-11E9-9278-68D0E5697425","name":"International IST Postdoc Fellowship Programme","grant_number":"291734"}],"_id":"939","oa":1,"title":"Waveguides with absorbing boundaries: Nonlinearity controlled by an exceptional point and solitons","publication":"Physical Review Letters","year":"2017","quality_controlled":"1","author":[{"last_name":"Midya","first_name":"Bikashkali","full_name":"Midya, Bikashkali","id":"456187FC-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Vladimir","last_name":"Konotop","full_name":"Konotop, Vladimir"}],"citation":{"ista":"Midya B, Konotop V. 2017. Waveguides with absorbing boundaries: Nonlinearity controlled by an exceptional point and solitons. Physical Review Letters. 119(3), 033905.","short":"B. Midya, V. Konotop, Physical Review Letters 119 (2017).","chicago":"Midya, Bikashkali, and Vladimir Konotop. “Waveguides with Absorbing Boundaries: Nonlinearity Controlled by an Exceptional Point and Solitons.” <i>Physical Review Letters</i>. American Physical Society, 2017. <a href=\"https://doi.org/10.1103/PhysRevLett.119.033905\">https://doi.org/10.1103/PhysRevLett.119.033905</a>.","ama":"Midya B, Konotop V. Waveguides with absorbing boundaries: Nonlinearity controlled by an exceptional point and solitons. <i>Physical Review Letters</i>. 2017;119(3). doi:<a href=\"https://doi.org/10.1103/PhysRevLett.119.033905\">10.1103/PhysRevLett.119.033905</a>","ieee":"B. Midya and V. Konotop, “Waveguides with absorbing boundaries: Nonlinearity controlled by an exceptional point and solitons,” <i>Physical Review Letters</i>, vol. 119, no. 3. American Physical Society, 2017.","apa":"Midya, B., &#38; Konotop, V. (2017). Waveguides with absorbing boundaries: Nonlinearity controlled by an exceptional point and solitons. <i>Physical Review Letters</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevLett.119.033905\">https://doi.org/10.1103/PhysRevLett.119.033905</a>","mla":"Midya, Bikashkali, and Vladimir Konotop. “Waveguides with Absorbing Boundaries: Nonlinearity Controlled by an Exceptional Point and Solitons.” <i>Physical Review Letters</i>, vol. 119, no. 3, 033905, American Physical Society, 2017, doi:<a href=\"https://doi.org/10.1103/PhysRevLett.119.033905\">10.1103/PhysRevLett.119.033905</a>."},"main_file_link":[{"url":"https://arxiv.org/abs/1706.04085 ","open_access":"1"}],"status":"public","article_number":"033905","month":"07","date_created":"2018-12-11T11:49:18Z","isi":1,"publist_id":"6481","intvolume":"       119","publisher":"American Physical Society","volume":119,"issue":"3","department":[{"_id":"MiLe"}],"doi":"10.1103/PhysRevLett.119.033905","language":[{"iso":"eng"}],"ec_funded":1,"day":"18","oa_version":"Submitted Version","date_updated":"2023-09-26T15:39:46Z","type":"journal_article","article_processing_charge":"No","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","scopus_import":"1","publication_identifier":{"issn":["00319007"]},"external_id":{"isi":["000405718200012"]},"date_published":"2017-07-18T00:00:00Z"},{"main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1705.09548"}],"citation":{"ista":"Rosenthal E, Chapman B, Higginbotham AP, Kerckhoff J, Lehnert K. 2017. Breaking Lorentz reciprocity with frequency conversion and delay. APS Physics, Physical Review Letters. 119(14), 147703.","short":"E. Rosenthal, B. Chapman, A.P. Higginbotham, J. Kerckhoff, K. Lehnert, APS Physics, Physical Review Letters 119 (2017).","chicago":"Rosenthal, Eric, Benjamin Chapman, Andrew P Higginbotham, Joseph Kerckhoff, and Konrad Lehnert. “Breaking Lorentz Reciprocity with Frequency Conversion and Delay.” <i>APS Physics, Physical Review Letters</i>. American Physical Society, 2017. <a href=\"https://doi.org/10.1103/PhysRevLett.119.147703\">https://doi.org/10.1103/PhysRevLett.119.147703</a>.","ieee":"E. Rosenthal, B. Chapman, A. P. Higginbotham, J. Kerckhoff, and K. Lehnert, “Breaking Lorentz reciprocity with frequency conversion and delay,” <i>APS Physics, Physical Review Letters</i>, vol. 119, no. 14. American Physical Society, 2017.","ama":"Rosenthal E, Chapman B, Higginbotham AP, Kerckhoff J, Lehnert K. Breaking Lorentz reciprocity with frequency conversion and delay. <i>APS Physics, Physical Review Letters</i>. 2017;119(14). doi:<a href=\"https://doi.org/10.1103/PhysRevLett.119.147703\">10.1103/PhysRevLett.119.147703</a>","mla":"Rosenthal, Eric, et al. “Breaking Lorentz Reciprocity with Frequency Conversion and Delay.” <i>APS Physics, Physical Review Letters</i>, vol. 119, no. 14, 147703, American Physical Society, 2017, doi:<a href=\"https://doi.org/10.1103/PhysRevLett.119.147703\">10.1103/PhysRevLett.119.147703</a>.","apa":"Rosenthal, E., Chapman, B., Higginbotham, A. P., Kerckhoff, J., &#38; Lehnert, K. (2017). Breaking Lorentz reciprocity with frequency conversion and delay. <i>APS Physics, Physical Review Letters</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevLett.119.147703\">https://doi.org/10.1103/PhysRevLett.119.147703</a>"},"quality_controlled":"1","author":[{"full_name":"Rosenthal, Eric","first_name":"Eric","last_name":"Rosenthal"},{"first_name":"Benjamin","last_name":"Chapman","full_name":"Chapman, Benjamin"},{"orcid":"0000-0003-2607-2363","full_name":"Higginbotham, Andrew P","id":"4AD6785A-F248-11E8-B48F-1D18A9856A87","first_name":"Andrew P","last_name":"Higginbotham"},{"last_name":"Kerckhoff","first_name":"Joseph","full_name":"Kerckhoff, Joseph"},{"full_name":"Lehnert, Konrad","last_name":"Lehnert","first_name":"Konrad"}],"extern":"1","year":"2017","title":"Breaking Lorentz reciprocity with frequency conversion and delay","publication":"APS Physics, Physical Review Letters","_id":"94","oa":1,"abstract":[{"lang":"eng","text":"We introduce a method for breaking Lorentz reciprocity based upon the noncommutation of frequency conversion and delay. The method requires no magnetic materials or resonant physics, allowing for the design of scalable and broadband nonreciprocal circuits. With this approach, two types of gyrators - universal building blocks for linear, nonreciprocal circuits - are constructed. Using one of these gyrators, we create a circulator with &gt;15 dB of isolation across the 5-9 GHz band. Our designs may be readily extended to any platform with suitable frequency conversion elements, including semiconducting devices for telecommunication or an on-chip superconducting implementation for quantum information processing."}],"publication_status":"published","volume":119,"issue":"14","publisher":"American Physical Society","intvolume":"       119","publist_id":"7960","month":"10","date_created":"2018-12-11T11:44:35Z","article_number":"147703","status":"public","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","oa_version":"Submitted Version","type":"journal_article","date_updated":"2021-01-12T08:22:04Z","day":"06","language":[{"iso":"eng"}],"doi":"10.1103/PhysRevLett.119.147703","external_id":{"arxiv":["1705.09548"]},"date_published":"2017-10-06T00:00:00Z","arxiv":1},{"month":"06","date_created":"2018-12-11T11:47:57Z","status":"public","intvolume":"       114","publist_id":"7013","file_date_updated":"2020-07-14T12:47:44Z","publisher":"National Academy of Sciences","volume":114,"issue":"26","abstract":[{"lang":"eng","text":"Many central synapses contain a single presynaptic active zone and a single postsynaptic density. Vesicular release statistics at such “simple synapses” indicate that they contain a small complement of docking sites where vesicles repetitively dock and fuse. In this work, we investigate functional and morphological aspects of docking sites at simple synapses made between cerebellar parallel fibers and molecular layer interneurons. Using immunogold labeling of SDS-treated freeze-fracture replicas, we find that Cav2.1 channels form several clusters per active zone with about nine channels per cluster. The mean value and range of intersynaptic variation are similar for Cav2.1 cluster numbers and for functional estimates of docking-site numbers obtained from the maximum numbers of released vesicles per action potential. Both numbers grow in relation with synaptic size and decrease by a similar extent with age between 2 wk and 4 wk postnatal. Thus, the mean docking-site numbers were 3.15 at 2 wk (range: 1–10) and 2.03 at 4 wk (range: 1–4), whereas the mean numbers of Cav2.1 clusters were 2.84 at 2 wk (range: 1–8) and 2.37 at 4 wk (range: 1–5). These changes were accompanied by decreases of miniature current amplitude (from 93 pA to 56 pA), active-zone surface area (from 0.0427 μm2 to 0.0234 μm2), and initial success rate (from 0.609 to 0.353), indicating a tightening of synaptic transmission with development. Altogether, these results suggest a close correspondence between the number of functionally defined vesicular docking sites and that of clusters of voltage-gated calcium channels. "}],"publication_status":"published","pmid":1,"publication":"PNAS","title":"Numbers of presynaptic Ca2+ channel clusters match those of functionally defined vesicular docking sites in single central synapses","_id":"693","ddc":["570"],"oa":1,"year":"2017","citation":{"ista":"Miki T, Kaufmann W, Malagon G, Gomez L, Tabuchi K, Watanabe M, Shigemoto R, Marty A. 2017. Numbers of presynaptic Ca2+ channel clusters match those of functionally defined vesicular docking sites in single central synapses. PNAS. 114(26), E5246–E5255.","short":"T. Miki, W. Kaufmann, G. Malagon, L. Gomez, K. Tabuchi, M. Watanabe, R. Shigemoto, A. Marty, PNAS 114 (2017) E5246–E5255.","chicago":"Miki, Takafumi, Walter Kaufmann, Gerardo Malagon, Laura Gomez, Katsuhiko Tabuchi, Masahiko Watanabe, Ryuichi Shigemoto, and Alain Marty. “Numbers of Presynaptic Ca2+ Channel Clusters Match Those of Functionally Defined Vesicular Docking Sites in Single Central Synapses.” <i>PNAS</i>. National Academy of Sciences, 2017. <a href=\"https://doi.org/10.1073/pnas.1704470114\">https://doi.org/10.1073/pnas.1704470114</a>.","ieee":"T. Miki <i>et al.</i>, “Numbers of presynaptic Ca2+ channel clusters match those of functionally defined vesicular docking sites in single central synapses,” <i>PNAS</i>, vol. 114, no. 26. National Academy of Sciences, pp. E5246–E5255, 2017.","ama":"Miki T, Kaufmann W, Malagon G, et al. Numbers of presynaptic Ca2+ channel clusters match those of functionally defined vesicular docking sites in single central synapses. <i>PNAS</i>. 2017;114(26):E5246-E5255. doi:<a href=\"https://doi.org/10.1073/pnas.1704470114\">10.1073/pnas.1704470114</a>","apa":"Miki, T., Kaufmann, W., Malagon, G., Gomez, L., Tabuchi, K., Watanabe, M., … Marty, A. (2017). Numbers of presynaptic Ca2+ channel clusters match those of functionally defined vesicular docking sites in single central synapses. <i>PNAS</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.1704470114\">https://doi.org/10.1073/pnas.1704470114</a>","mla":"Miki, Takafumi, et al. “Numbers of Presynaptic Ca2+ Channel Clusters Match Those of Functionally Defined Vesicular Docking Sites in Single Central Synapses.” <i>PNAS</i>, vol. 114, no. 26, National Academy of Sciences, 2017, pp. E5246–55, doi:<a href=\"https://doi.org/10.1073/pnas.1704470114\">10.1073/pnas.1704470114</a>."},"author":[{"last_name":"Miki","first_name":"Takafumi","full_name":"Miki, Takafumi"},{"id":"3F99E422-F248-11E8-B48F-1D18A9856A87","full_name":"Kaufmann, Walter","orcid":"0000-0001-9735-5315","first_name":"Walter","last_name":"Kaufmann"},{"last_name":"Malagon","first_name":"Gerardo","full_name":"Malagon, Gerardo"},{"full_name":"Gomez, Laura","first_name":"Laura","last_name":"Gomez"},{"first_name":"Katsuhiko","last_name":"Tabuchi","full_name":"Tabuchi, Katsuhiko"},{"first_name":"Masahiko","last_name":"Watanabe","full_name":"Watanabe, Masahiko"},{"id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","full_name":"Shigemoto, Ryuichi","orcid":"0000-0001-8761-9444","first_name":"Ryuichi","last_name":"Shigemoto"},{"first_name":"Alain","last_name":"Marty","full_name":"Marty, Alain"}],"quality_controlled":"1","scopus_import":1,"publication_identifier":{"issn":["00278424"]},"file":[{"checksum":"2ab75d554f3df4a34d20fa8040589b7e","file_name":"2017_PNAS_Miki.pdf","access_level":"open_access","date_updated":"2020-07-14T12:47:44Z","file_id":"7223","content_type":"application/pdf","creator":"kschuh","file_size":2721544,"relation":"main_file","date_created":"2020-01-03T13:27:29Z"}],"external_id":{"pmid":["28607047"]},"date_published":"2017-06-27T00:00:00Z","page":"E5246 - E5255","department":[{"_id":"EM-Fac"},{"_id":"RySh"}],"has_accepted_license":"1","doi":"10.1073/pnas.1704470114","language":[{"iso":"eng"}],"oa_version":"Published Version","type":"journal_article","date_updated":"2023-02-23T12:54:57Z","day":"27","article_processing_charge":"Yes (in subscription journal)","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87"},{"conference":{"name":"PODC: Principles of Distributed Computing","end_date":"2017-07-27","location":"Washington, DC, United States","start_date":"2017-07-25"},"month":"07","date_created":"2019-10-08T12:47:46Z","status":"public","publication_identifier":{"isbn":["9781450349925"]},"publisher":"ACM Press","date_published":"2017-07-01T00:00:00Z","page":"101-110","abstract":[{"lang":"eng","text":"LCLs or locally checkable labelling problems (e.g. maximal independent set, maximal matching, and vertex colouring) in the LOCAL model of computation are very well-understood in cycles (toroidal 1-dimensional grids): every problem has a complexity of O(1), Θ(log* n), or Θ(n), and the design of optimal algorithms can be fully automated. This work develops the complexity theory of LCL problems for toroidal 2-dimensional grids. The complexity classes are the same as in the 1-dimensional case: O(1), Θ(log* n), and Θ(n). However, given an LCL problem it is undecidable whether its complexity is Θ(log* n) or Θ(n) in 2-dimensional grids.\r\nNevertheless, if we correctly guess that the complexity of a problem is Θ(log* n), we can completely automate the design of optimal algorithms. For any problem we can find an algorithm that is of a normal form A' o Sk, where A' is a finite function, Sk is an algorithm for finding a maximal independent set in kth power of the grid, and k is a constant.\r\nFinally, partially with the help of automated design tools, we classify the complexity of several concrete LCL problems related to colourings and orientations."}],"publication_status":"published","title":"LCL problems on grids","_id":"6932","doi":"10.1145/3087801.3087833","language":[{"iso":"eng"}],"oa_version":"None","type":"conference","date_updated":"2021-01-12T08:09:39Z","year":"2017","day":"01","citation":{"ama":"Brandt S, Hirvonen J, Korhonen JH, et al. LCL problems on grids. In: ACM Press; 2017:101-110. doi:<a href=\"https://doi.org/10.1145/3087801.3087833\">10.1145/3087801.3087833</a>","ieee":"S. Brandt <i>et al.</i>, “LCL problems on grids,” presented at the PODC: Principles of Distributed Computing, Washington, DC, United States, 2017, pp. 101–110.","chicago":"Brandt, Sebastian, Juho Hirvonen, Janne H. Korhonen, Tuomo Lempiäinen, Patric R.J. Östergård, Christopher Purcell, Joel Rybicki, Jukka Suomela, and Przemysław Uznański. “LCL Problems on Grids,” 101–10. ACM Press, 2017. <a href=\"https://doi.org/10.1145/3087801.3087833\">https://doi.org/10.1145/3087801.3087833</a>.","short":"S. Brandt, J. Hirvonen, J.H. Korhonen, T. Lempiäinen, P.R.J. Östergård, C. Purcell, J. Rybicki, J. Suomela, P. Uznański, in:, ACM Press, 2017, pp. 101–110.","ista":"Brandt S, Hirvonen J, Korhonen JH, Lempiäinen T, Östergård PRJ, Purcell C, Rybicki J, Suomela J, Uznański P. 2017. LCL problems on grids. PODC: Principles of Distributed Computing, 101–110.","mla":"Brandt, Sebastian, et al. <i>LCL Problems on Grids</i>. ACM Press, 2017, pp. 101–10, doi:<a href=\"https://doi.org/10.1145/3087801.3087833\">10.1145/3087801.3087833</a>.","apa":"Brandt, S., Hirvonen, J., Korhonen, J. H., Lempiäinen, T., Östergård, P. R. J., Purcell, C., … Uznański, P. (2017). LCL problems on grids (pp. 101–110). Presented at the PODC: Principles of Distributed Computing, Washington, DC, United States: ACM Press. <a href=\"https://doi.org/10.1145/3087801.3087833\">https://doi.org/10.1145/3087801.3087833</a>"},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","quality_controlled":"1","extern":"1","article_processing_charge":"No","author":[{"full_name":"Brandt, Sebastian","last_name":"Brandt","first_name":"Sebastian"},{"full_name":"Hirvonen, Juho","first_name":"Juho","last_name":"Hirvonen"},{"last_name":"Korhonen","first_name":"Janne H.","full_name":"Korhonen, Janne H."},{"first_name":"Tuomo","last_name":"Lempiäinen","full_name":"Lempiäinen, Tuomo"},{"first_name":"Patric R.J.","last_name":"Östergård","full_name":"Östergård, Patric R.J."},{"full_name":"Purcell, Christopher","last_name":"Purcell","first_name":"Christopher"},{"orcid":"0000-0002-6432-6646","full_name":"Rybicki, Joel","id":"334EFD2E-F248-11E8-B48F-1D18A9856A87","last_name":"Rybicki","first_name":"Joel"},{"full_name":"Suomela, Jukka","last_name":"Suomela","first_name":"Jukka"},{"full_name":"Uznański, Przemysław","last_name":"Uznański","first_name":"Przemysław"}]},{"intvolume":"       130","publist_id":"7008","month":"07","date_created":"2018-12-11T11:47:58Z","status":"public","volume":130,"issue":"13","file_date_updated":"2020-07-14T12:47:45Z","publisher":"Company of Biologists","article_type":"original","pmid":1,"title":"A dual phenotype of MDA MB 468 cancer cells reveals mutual regulation of tensin3 and adhesion plasticity","publication":"Journal of Cell Science","_id":"694","ddc":["570"],"oa":1,"abstract":[{"text":"A change regarding the extent of adhesion - hereafter referred to as adhesion plasticity - between adhesive and less-adhesive states of mammalian cells is important for their behavior. To investigate adhesion plasticity, we have selected a stable isogenic subpopulation of human MDA-MB-468 breast carcinoma cells growing in suspension. These suspension cells are unable to re-adhere to various matrices or to contract three-dimensional collagen lattices. By using transcriptome analysis, we identified the focal adhesion protein tensin3 (Tns3) as a determinant of adhesion plasticity. Tns3 is strongly reduced at mRNA and protein levels in suspension cells. Furthermore, by transiently challenging breast cancer cells to grow under non-adherent conditions markedly reduces Tns3 protein expression, which is regained upon re-adhesion. Stable knockdown of Tns3 in parental MDA-MB-468 cells results in defective adhesion, spreading and migration. Tns3-knockdown cells display impaired structure and dynamics of focal adhesion complexes as determined by immunostaining. Restoration of Tns3 protein expression in suspension cells partially rescues adhesion and focal contact composition. Our work identifies Tns3 as a crucial focal adhesion component regulated by, and functionally contributing to, the switch between adhesive and non-adhesive states in MDA-MB-468 cancer cells.","lang":"eng"}],"publication_status":"published","citation":{"mla":"Veß, Astrid, et al. “A Dual Phenotype of MDA MB 468 Cancer Cells Reveals Mutual Regulation of Tensin3 and Adhesion Plasticity.” <i>Journal of Cell Science</i>, vol. 130, no. 13, Company of Biologists, 2017, pp. 2172–84, doi:<a href=\"https://doi.org/10.1242/jcs.200899\">10.1242/jcs.200899</a>.","apa":"Veß, A., Blache, U., Leitner, L., Kurz, A., Ehrenpfordt, A., Sixt, M. K., &#38; Posern, G. (2017). A dual phenotype of MDA MB 468 cancer cells reveals mutual regulation of tensin3 and adhesion plasticity. <i>Journal of Cell Science</i>. Company of Biologists. <a href=\"https://doi.org/10.1242/jcs.200899\">https://doi.org/10.1242/jcs.200899</a>","short":"A. Veß, U. Blache, L. Leitner, A. Kurz, A. Ehrenpfordt, M.K. Sixt, G. Posern, Journal of Cell Science 130 (2017) 2172–2184.","chicago":"Veß, Astrid, Ulrich Blache, Laura Leitner, Angela Kurz, Anja Ehrenpfordt, Michael K Sixt, and Guido Posern. “A Dual Phenotype of MDA MB 468 Cancer Cells Reveals Mutual Regulation of Tensin3 and Adhesion Plasticity.” <i>Journal of Cell Science</i>. Company of Biologists, 2017. <a href=\"https://doi.org/10.1242/jcs.200899\">https://doi.org/10.1242/jcs.200899</a>.","ista":"Veß A, Blache U, Leitner L, Kurz A, Ehrenpfordt A, Sixt MK, Posern G. 2017. A dual phenotype of MDA MB 468 cancer cells reveals mutual regulation of tensin3 and adhesion plasticity. Journal of Cell Science. 130(13), 2172–2184.","ieee":"A. Veß <i>et al.</i>, “A dual phenotype of MDA MB 468 cancer cells reveals mutual regulation of tensin3 and adhesion plasticity,” <i>Journal of Cell Science</i>, vol. 130, no. 13. Company of Biologists, pp. 2172–2184, 2017.","ama":"Veß A, Blache U, Leitner L, et al. A dual phenotype of MDA MB 468 cancer cells reveals mutual regulation of tensin3 and adhesion plasticity. <i>Journal of Cell Science</i>. 2017;130(13):2172-2184. doi:<a href=\"https://doi.org/10.1242/jcs.200899\">10.1242/jcs.200899</a>"},"author":[{"full_name":"Veß, Astrid","last_name":"Veß","first_name":"Astrid"},{"last_name":"Blache","first_name":"Ulrich","full_name":"Blache, Ulrich"},{"full_name":"Leitner, Laura","last_name":"Leitner","first_name":"Laura"},{"first_name":"Angela","last_name":"Kurz","full_name":"Kurz, Angela"},{"full_name":"Ehrenpfordt, Anja","first_name":"Anja","last_name":"Ehrenpfordt"},{"full_name":"Sixt, Michael K","orcid":"0000-0002-6620-9179","id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87","last_name":"Sixt","first_name":"Michael K"},{"first_name":"Guido","last_name":"Posern","full_name":"Posern, Guido"}],"quality_controlled":"1","year":"2017","scopus_import":1,"publication_identifier":{"issn":["00219533"]},"file":[{"access_level":"open_access","checksum":"42c81a0a4fc3128883b391c3af3f74bc","file_name":"2017_CellScience_Vess.pdf","file_id":"6966","date_updated":"2020-07-14T12:47:45Z","content_type":"application/pdf","creator":"dernst","file_size":10847596,"date_created":"2019-10-24T09:43:56Z","relation":"main_file"}],"external_id":{"pmid":["28515231"]},"date_published":"2017-07-01T00:00:00Z","page":"2172 - 2184","department":[{"_id":"MiSi"}],"has_accepted_license":"1","language":[{"iso":"eng"}],"doi":"10.1242/jcs.200899","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Published Version","date_updated":"2021-01-12T08:09:41Z","type":"journal_article","day":"01"},{"publist_id":"7007","publication_identifier":{"issn":["03672530"]},"intvolume":"       232","status":"public","date_created":"2018-12-11T11:47:58Z","month":"07","volume":232,"page":"7 - 15","date_published":"2017-07-01T00:00:00Z","publisher":"Elsevier","language":[{"iso":"eng"}],"doi":"10.1016/j.flora.2017.02.020","_id":"695","title":"A perfume collecting male oil bee? Evidences of a novel pollination system involving Anthurium acutifolium Araceae and Paratetrapedia chocoensis Apidae Tapinotaspidini","publication":"Flora: Morphology, Distribution, Functional Ecology of Plants","publication_status":"published","abstract":[{"text":"It has been known since Stefan Vogel's observations in 1969 that solitary female oil bees collect fatty floral oils from specialized oil-secreting plants with the aid of hairy patches on either their legs or abdomen, a reward used as food for their larvae and/or to line their brood cells. Similar adaptations are also known from male oil bees, although the purpose of their oil-collecting behavior has not yet been clarified. Here, we describe a novel pollination system involving male Paratetrapedia oil bees and the tropical herb Anthurium acutifolium. We present ultrastructural morphological details of bee and plant structures involved in this interaction and the composition of floral scents likely mediating pollinator attraction. Inflorescences of A. acutifolium were visited almost exclusively by male P. chocoensis oil bees. The bees mopped with a hairy patch of their abdominal sterna 3 across the inflorescence surface. During this activity on both staminate and pistillate stage inflorescences, bees’ abdomens and legs became loaded with pollen and contacted receptive stigmas. In contrast to what has been observed in other angiosperms visited for the collection of fatty floral oils, the inflorescences/flowers of A. acutifolium do not have structures specialized in oil secretion, i.e., elaiophores. These inflorescences, nonetheless, were strongly scented during the time interval they were visited by the bees. Gas chromatography/mass spectrometry (GC/MS) analyses of dynamic headspace floral samples revealed that inflorescences of both anthetic phases emitted scent bouquets consisting mainly of aliphatic esters, indole and uncommmon terpenoids (megastigmanes). Interestingly enough, our data suggest that the unusual floral scent of A. acutifolium is a perfume reward collected by male P. chocoensis oil bees. This pollination system thus bears a remarkable resemblence with the interactions between perfume-collecting male euglossine bees and their preferred flowers, discovered by Stefan Vogel half a century ago.","lang":"eng"}],"author":[{"full_name":"Etl, Florian","last_name":"Etl","first_name":"Florian"},{"id":"480826C8-F248-11E8-B48F-1D18A9856A87","full_name":"Franschitz, Anna","first_name":"Anna","last_name":"Franschitz"},{"full_name":"Aguiar, Antonio","last_name":"Aguiar","first_name":"Antonio"},{"full_name":"Schönenberger, Jürg","last_name":"Schönenberger","first_name":"Jürg"},{"last_name":"Dötterl","first_name":"Stefan","full_name":"Dötterl, Stefan"}],"extern":"1","user_id":"4435EBFC-F248-11E8-B48F-1D18A9856A87","quality_controlled":"1","citation":{"mla":"Etl, Florian, et al. “A Perfume Collecting Male Oil Bee? Evidences of a Novel Pollination System Involving Anthurium Acutifolium Araceae and Paratetrapedia Chocoensis Apidae Tapinotaspidini.” <i>Flora: Morphology, Distribution, Functional Ecology of Plants</i>, vol. 232, Elsevier, 2017, pp. 7–15, doi:<a href=\"https://doi.org/10.1016/j.flora.2017.02.020\">10.1016/j.flora.2017.02.020</a>.","apa":"Etl, F., Franschitz, A., Aguiar, A., Schönenberger, J., &#38; Dötterl, S. (2017). A perfume collecting male oil bee? Evidences of a novel pollination system involving Anthurium acutifolium Araceae and Paratetrapedia chocoensis Apidae Tapinotaspidini. <i>Flora: Morphology, Distribution, Functional Ecology of Plants</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.flora.2017.02.020\">https://doi.org/10.1016/j.flora.2017.02.020</a>","ieee":"F. Etl, A. Franschitz, A. Aguiar, J. Schönenberger, and S. Dötterl, “A perfume collecting male oil bee? Evidences of a novel pollination system involving Anthurium acutifolium Araceae and Paratetrapedia chocoensis Apidae Tapinotaspidini,” <i>Flora: Morphology, Distribution, Functional Ecology of Plants</i>, vol. 232. Elsevier, pp. 7–15, 2017.","ama":"Etl F, Franschitz A, Aguiar A, Schönenberger J, Dötterl S. A perfume collecting male oil bee? Evidences of a novel pollination system involving Anthurium acutifolium Araceae and Paratetrapedia chocoensis Apidae Tapinotaspidini. <i>Flora: Morphology, Distribution, Functional Ecology of Plants</i>. 2017;232:7-15. doi:<a href=\"https://doi.org/10.1016/j.flora.2017.02.020\">10.1016/j.flora.2017.02.020</a>","ista":"Etl F, Franschitz A, Aguiar A, Schönenberger J, Dötterl S. 2017. A perfume collecting male oil bee? Evidences of a novel pollination system involving Anthurium acutifolium Araceae and Paratetrapedia chocoensis Apidae Tapinotaspidini. Flora: Morphology, Distribution, Functional Ecology of Plants. 232, 7–15.","short":"F. Etl, A. Franschitz, A. Aguiar, J. Schönenberger, S. Dötterl, Flora: Morphology, Distribution, Functional Ecology of Plants 232 (2017) 7–15.","chicago":"Etl, Florian, Anna Franschitz, Antonio Aguiar, Jürg Schönenberger, and Stefan Dötterl. “A Perfume Collecting Male Oil Bee? Evidences of a Novel Pollination System Involving Anthurium Acutifolium Araceae and Paratetrapedia Chocoensis Apidae Tapinotaspidini.” <i>Flora: Morphology, Distribution, Functional Ecology of Plants</i>. Elsevier, 2017. <a href=\"https://doi.org/10.1016/j.flora.2017.02.020\">https://doi.org/10.1016/j.flora.2017.02.020</a>."},"day":"01","year":"2017","type":"journal_article","date_updated":"2021-01-12T08:09:44Z","oa_version":"None"},{"date_created":"2018-12-11T11:47:58Z","month":"07","status":"public","article_number":"e1005609","intvolume":"        13","publist_id":"7004","file_date_updated":"2020-07-14T12:47:46Z","article_type":"original","publisher":"Public Library of Science","volume":13,"issue":"7","pubrep_id":"894","project":[{"call_identifier":"FP7","_id":"25B1EC9E-B435-11E9-9278-68D0E5697425","grant_number":"618091","name":"Speed of Adaptation in Population Genetics and Evolutionary Computation"}],"publication_status":"published","abstract":[{"lang":"eng","text":"Mutator strains are expected to evolve when the availability and effect of beneficial mutations are high enough to counteract the disadvantage from deleterious mutations that will inevitably accumulate. As the population becomes more adapted to its environment, both availability and effect of beneficial mutations necessarily decrease and mutation rates are predicted to decrease. It has been shown that certain molecular mechanisms can lead to increased mutation rates when the organism finds itself in a stressful environment. While this may be a correlated response to other functions, it could also be an adaptive mechanism, raising mutation rates only when it is most advantageous. Here, we use a mathematical model to investigate the plausibility of the adaptive hypothesis. We show that such a mechanism can be mantained if the population is subjected to diverse stresses. By simulating various antibiotic treatment schemes, we find that combination treatments can reduce the effectiveness of second-order selection on stress-induced mutagenesis. We discuss the implications of our results to strategies of antibiotic therapy."}],"publication":"PLoS Computational Biology","title":"Stress induced mutagenesis: Stress diversity facilitates the persistence of mutator genes","ddc":["576"],"oa":1,"related_material":{"record":[{"relation":"research_data","status":"public","id":"9849"},{"relation":"research_data","status":"public","id":"9850"},{"id":"9851","relation":"research_data","status":"public"},{"id":"9852","status":"public","relation":"research_data"},{"relation":"dissertation_contains","status":"public","id":"6263"}]},"_id":"696","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"year":"2017","citation":{"mla":"Lukacisinova, Marta, et al. “Stress Induced Mutagenesis: Stress Diversity Facilitates the Persistence of Mutator Genes.” <i>PLoS Computational Biology</i>, vol. 13, no. 7, e1005609, Public Library of Science, 2017, doi:<a href=\"https://doi.org/10.1371/journal.pcbi.1005609\">10.1371/journal.pcbi.1005609</a>.","apa":"Lukacisinova, M., Novak, S., &#38; Paixao, T. (2017). Stress induced mutagenesis: Stress diversity facilitates the persistence of mutator genes. <i>PLoS Computational Biology</i>. Public Library of Science. <a href=\"https://doi.org/10.1371/journal.pcbi.1005609\">https://doi.org/10.1371/journal.pcbi.1005609</a>","ieee":"M. Lukacisinova, S. Novak, and T. Paixao, “Stress induced mutagenesis: Stress diversity facilitates the persistence of mutator genes,” <i>PLoS Computational Biology</i>, vol. 13, no. 7. Public Library of Science, 2017.","ama":"Lukacisinova M, Novak S, Paixao T. Stress induced mutagenesis: Stress diversity facilitates the persistence of mutator genes. <i>PLoS Computational Biology</i>. 2017;13(7). doi:<a href=\"https://doi.org/10.1371/journal.pcbi.1005609\">10.1371/journal.pcbi.1005609</a>","short":"M. Lukacisinova, S. Novak, T. Paixao, PLoS Computational Biology 13 (2017).","chicago":"Lukacisinova, Marta, Sebastian Novak, and Tiago Paixao. “Stress Induced Mutagenesis: Stress Diversity Facilitates the Persistence of Mutator Genes.” <i>PLoS Computational Biology</i>. Public Library of Science, 2017. <a href=\"https://doi.org/10.1371/journal.pcbi.1005609\">https://doi.org/10.1371/journal.pcbi.1005609</a>.","ista":"Lukacisinova M, Novak S, Paixao T. 2017. Stress induced mutagenesis: Stress diversity facilitates the persistence of mutator genes. PLoS Computational Biology. 13(7), e1005609."},"author":[{"full_name":"Lukacisinova, Marta","orcid":"0000-0002-2519-8004","id":"4342E402-F248-11E8-B48F-1D18A9856A87","first_name":"Marta","last_name":"Lukacisinova"},{"orcid":"0000-0002-2519-824X","full_name":"Novak, Sebastian","id":"461468AE-F248-11E8-B48F-1D18A9856A87","first_name":"Sebastian","last_name":"Novak"},{"first_name":"Tiago","last_name":"Paixao","id":"2C5658E6-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-2361-3953","full_name":"Paixao, Tiago"}],"quality_controlled":"1","publication_identifier":{"issn":["1553734X"]},"scopus_import":1,"date_published":"2017-07-18T00:00:00Z","file":[{"content_type":"application/pdf","creator":"system","file_size":3775716,"relation":"main_file","date_created":"2018-12-12T10:15:01Z","checksum":"9143c290fa6458ed2563bff4b295554a","file_name":"IST-2017-894-v1+1_journal.pcbi.1005609.pdf","access_level":"open_access","date_updated":"2020-07-14T12:47:46Z","file_id":"5117"}],"ec_funded":1,"language":[{"iso":"eng"}],"license":"https://creativecommons.org/licenses/by/4.0/","doi":"10.1371/journal.pcbi.1005609","has_accepted_license":"1","department":[{"_id":"ToBo"},{"_id":"NiBa"},{"_id":"CaGu"}],"type":"journal_article","date_updated":"2024-03-25T23:30:14Z","oa_version":"Published Version","day":"18","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87"},{"month":"07","conference":{"start_date":"2017-07-10","location":"Warsaw, Poland","name":"ICALP: International Colloquium on Automata, Languages, and Programming","end_date":"2017-07-14"},"date_created":"2018-12-11T11:47:59Z","article_number":"39","status":"public","intvolume":"        80","publist_id":"7003","file_date_updated":"2020-07-14T12:47:46Z","publisher":"Schloss Dagstuhl - Leibniz-Zentrum für Informatik","pubrep_id":"893","volume":80,"project":[{"grant_number":"682815","name":"Teaching Old Crypto New Tricks","_id":"258AA5B2-B435-11E9-9278-68D0E5697425","call_identifier":"H2020"}],"abstract":[{"text":"De, Trevisan and Tulsiani [CRYPTO 2010] show that every distribution over n-bit strings which has constant statistical distance to uniform (e.g., the output of a pseudorandom generator mapping n-1 to n bit strings), can be distinguished from the uniform distribution with advantage epsilon by a circuit of size O( 2^n epsilon^2). We generalize this result, showing that a distribution which has less than k bits of min-entropy, can be distinguished from any distribution with k bits of delta-smooth min-entropy with advantage epsilon by a circuit of size O(2^k epsilon^2/delta^2). As a special case, this implies that any distribution with support at most 2^k (e.g., the output of a pseudoentropy generator mapping k to n bit strings) can be distinguished from any given distribution with min-entropy k+1 with advantage epsilon by a circuit of size O(2^k epsilon^2). Our result thus shows that pseudoentropy distributions face basically the same non-uniform attacks as pseudorandom distributions. ","lang":"eng"}],"publication_status":"published","title":"Non uniform attacks against pseudoentropy","_id":"697","ddc":["005"],"oa":1,"tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"year":"2017","citation":{"ista":"Pietrzak KZ, Skórski M. 2017. Non uniform attacks against pseudoentropy. ICALP: International Colloquium on Automata, Languages, and Programming, LIPIcs, vol. 80, 39.","short":"K.Z. Pietrzak, M. Skórski, in:, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2017.","chicago":"Pietrzak, Krzysztof Z, and Maciej Skórski. “Non Uniform Attacks against Pseudoentropy,” Vol. 80. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2017. <a href=\"https://doi.org/10.4230/LIPIcs.ICALP.2017.39\">https://doi.org/10.4230/LIPIcs.ICALP.2017.39</a>.","ama":"Pietrzak KZ, Skórski M. Non uniform attacks against pseudoentropy. In: Vol 80. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2017. doi:<a href=\"https://doi.org/10.4230/LIPIcs.ICALP.2017.39\">10.4230/LIPIcs.ICALP.2017.39</a>","ieee":"K. Z. Pietrzak and M. Skórski, “Non uniform attacks against pseudoentropy,” presented at the ICALP: International Colloquium on Automata, Languages, and Programming, Warsaw, Poland, 2017, vol. 80.","mla":"Pietrzak, Krzysztof Z., and Maciej Skórski. <i>Non Uniform Attacks against Pseudoentropy</i>. Vol. 80, 39, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2017, doi:<a href=\"https://doi.org/10.4230/LIPIcs.ICALP.2017.39\">10.4230/LIPIcs.ICALP.2017.39</a>.","apa":"Pietrzak, K. Z., &#38; Skórski, M. (2017). Non uniform attacks against pseudoentropy (Vol. 80). Presented at the ICALP: International Colloquium on Automata, Languages, and Programming, Warsaw, Poland: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. <a href=\"https://doi.org/10.4230/LIPIcs.ICALP.2017.39\">https://doi.org/10.4230/LIPIcs.ICALP.2017.39</a>"},"quality_controlled":"1","author":[{"first_name":"Krzysztof Z","last_name":"Pietrzak","id":"3E04A7AA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-9139-1654","full_name":"Pietrzak, Krzysztof Z"},{"id":"EC09FA6A-02D0-11E9-8223-86B7C91467DD","full_name":"Skórski, Maciej","last_name":"Skórski","first_name":"Maciej"}],"alternative_title":["LIPIcs"],"scopus_import":1,"publication_identifier":{"issn":["18688969"]},"file":[{"relation":"main_file","date_created":"2018-12-12T10:08:40Z","file_size":601004,"creator":"system","content_type":"application/pdf","file_id":"4701","date_updated":"2020-07-14T12:47:46Z","checksum":"e95618a001692f1af2d68f5fde43bc1f","file_name":"IST-2017-893-v1+1_LIPIcs-ICALP-2017-39.pdf","access_level":"open_access"}],"date_published":"2017-07-01T00:00:00Z","ec_funded":1,"has_accepted_license":"1","department":[{"_id":"KrPi"}],"doi":"10.4230/LIPIcs.ICALP.2017.39","language":[{"iso":"eng"}],"oa_version":"Published Version","type":"conference","date_updated":"2021-01-12T08:11:15Z","day":"01","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87"},{"language":[{"iso":"eng"}],"license":"https://creativecommons.org/licenses/by-nc-sa/4.0/","doi":"10.1091/mbc.E16-12-0825","has_accepted_license":"1","department":[{"_id":"CaUh"}],"day":"07","type":"journal_article","date_updated":"2021-01-12T08:11:17Z","oa_version":"Published Version","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"issn":["10591524"]},"scopus_import":1,"page":"1997 - 2009","date_published":"2017-07-07T00:00:00Z","file":[{"file_name":"IST-2017-892-v1+1_Mol._Biol._Cell-2017-Wang-1997-2009.pdf","checksum":"de01dac9e30970cfa6ae902480a4e04d","access_level":"open_access","date_updated":"2020-07-14T12:47:46Z","file_id":"4844","creator":"system","content_type":"application/pdf","file_size":1086097,"relation":"main_file","date_created":"2018-12-12T10:10:53Z"}],"publication_status":"published","abstract":[{"lang":"eng","text":"Extracellular matrix signals from the microenvironment regulate gene expression patterns and cell behavior. Using a combination of experiments and geometric models, we demonstrate correlations between cell geometry, three-dimensional (3D) organization of chromosome territories, and gene expression. Fluorescence in situ hybridization experiments showed that micropatterned fibroblasts cultured on anisotropic versus isotropic substrates resulted in repositioning of specific chromosomes, which contained genes that were differentially regulated by cell geometries. Experiments combined with ellipsoid packing models revealed that the mechanosensitivity of chromosomes was correlated with their orientation in the nucleus. Transcription inhibition experiments suggested that the intermingling degree was more sensitive to global changes in transcription than to chromosome radial positioning and its orientations. These results suggested that cell geometry modulated 3D chromosome arrangement, and their neighborhoods correlated with gene expression patterns in a predictable manner. This is central to understanding geometric control of genetic programs involved in cellular homeostasis and the associated diseases. "}],"project":[{"name":"Gaussian Graphical Models: Theory and Applications","grant_number":"Y 903-N35","call_identifier":"FWF","_id":"2530CA10-B435-11E9-9278-68D0E5697425"}],"ddc":["519"],"oa":1,"_id":"698","title":"Orientation and repositioning of chromosomes correlate with cell geometry dependent gene expression","publication":"Molecular Biology of the Cell","year":"2017","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode","short":"CC BY-NC-SA (4.0)","name":"Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)","image":"/images/cc_by_nc_sa.png"},"author":[{"full_name":"Wang, Yejun","first_name":"Yejun","last_name":"Wang"},{"full_name":"Nagarajan, Mallika","last_name":"Nagarajan","first_name":"Mallika"},{"last_name":"Uhler","first_name":"Caroline","id":"49ADD78E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-7008-0216","full_name":"Uhler, Caroline"},{"full_name":"Shivashankar, Gv","first_name":"Gv","last_name":"Shivashankar"}],"quality_controlled":"1","citation":{"apa":"Wang, Y., Nagarajan, M., Uhler, C., &#38; Shivashankar, G. (2017). Orientation and repositioning of chromosomes correlate with cell geometry dependent gene expression. <i>Molecular Biology of the Cell</i>. American Society for Cell Biology. <a href=\"https://doi.org/10.1091/mbc.E16-12-0825\">https://doi.org/10.1091/mbc.E16-12-0825</a>","mla":"Wang, Yejun, et al. “Orientation and Repositioning of Chromosomes Correlate with Cell Geometry Dependent Gene Expression.” <i>Molecular Biology of the Cell</i>, vol. 28, no. 14, American Society for Cell Biology, 2017, pp. 1997–2009, doi:<a href=\"https://doi.org/10.1091/mbc.E16-12-0825\">10.1091/mbc.E16-12-0825</a>.","ista":"Wang Y, Nagarajan M, Uhler C, Shivashankar G. 2017. Orientation and repositioning of chromosomes correlate with cell geometry dependent gene expression. Molecular Biology of the Cell. 28(14), 1997–2009.","short":"Y. Wang, M. Nagarajan, C. Uhler, G. Shivashankar, Molecular Biology of the Cell 28 (2017) 1997–2009.","chicago":"Wang, Yejun, Mallika Nagarajan, Caroline Uhler, and Gv Shivashankar. “Orientation and Repositioning of Chromosomes Correlate with Cell Geometry Dependent Gene Expression.” <i>Molecular Biology of the Cell</i>. American Society for Cell Biology, 2017. <a href=\"https://doi.org/10.1091/mbc.E16-12-0825\">https://doi.org/10.1091/mbc.E16-12-0825</a>.","ieee":"Y. Wang, M. Nagarajan, C. Uhler, and G. Shivashankar, “Orientation and repositioning of chromosomes correlate with cell geometry dependent gene expression,” <i>Molecular Biology of the Cell</i>, vol. 28, no. 14. American Society for Cell Biology, pp. 1997–2009, 2017.","ama":"Wang Y, Nagarajan M, Uhler C, Shivashankar G. Orientation and repositioning of chromosomes correlate with cell geometry dependent gene expression. <i>Molecular Biology of the Cell</i>. 2017;28(14):1997-2009. doi:<a href=\"https://doi.org/10.1091/mbc.E16-12-0825\">10.1091/mbc.E16-12-0825</a>"},"status":"public","date_created":"2018-12-11T11:47:59Z","month":"07","publist_id":"7001","intvolume":"        28","publisher":"American Society for Cell Biology","file_date_updated":"2020-07-14T12:47:46Z","volume":28,"issue":"14","pubrep_id":"892"},{"doi":"10.1073/pnas.1702020114","language":[{"iso":"eng"}],"department":[{"_id":"KrCh"}],"day":"03","type":"journal_article","date_updated":"2021-01-12T08:11:21Z","oa_version":"Submitted Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"issn":["00278424"]},"scopus_import":1,"page":"E5396 - E5405","date_published":"2017-07-03T00:00:00Z","external_id":{"pmid":["28630336"]},"publication_status":"published","abstract":[{"lang":"eng","text":"In antagonistic symbioses, such as host–parasite interactions, one population’s success is the other’s loss. In mutualistic symbioses, such as division of labor, both parties can gain, but they might have different preferences over the possible mutualistic arrangements. The rates of evolution of the two populations in a symbiosis are important determinants of which population will be more successful: Faster evolution is thought to be favored in antagonistic symbioses (the “Red Queen effect”), but disfavored in certain mutualistic symbioses (the “Red King effect”). However, it remains unclear which biological parameters drive these effects. Here, we analyze the effects of the various determinants of evolutionary rate: generation time, mutation rate, population size, and the intensity of natural selection. Our main results hold for the case where mutation is infrequent. Slower evolution causes a long-term advantage in an important class of mutualistic interactions. Surprisingly, less intense selection is the strongest driver of this Red King effect, whereas relative mutation rates and generation times have little effect. In antagonistic interactions, faster evolution by any means is beneficial. Our results provide insight into the demographic evolution of symbionts. "}],"oa":1,"_id":"699","title":"The red queen and king in finite populations","publication":"PNAS","pmid":1,"year":"2017","quality_controlled":"1","author":[{"first_name":"Carl","last_name":"Veller","full_name":"Veller, Carl"},{"first_name":"Laura","last_name":"Hayward","full_name":"Hayward, Laura"},{"last_name":"Nowak","first_name":"Martin","full_name":"Nowak, Martin"},{"first_name":"Christian","last_name":"Hilbe","orcid":"0000-0001-5116-955X","full_name":"Hilbe, Christian","id":"2FDF8F3C-F248-11E8-B48F-1D18A9856A87"}],"main_file_link":[{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502615/","open_access":"1"}],"citation":{"apa":"Veller, C., Hayward, L., Nowak, M., &#38; Hilbe, C. (2017). The red queen and king in finite populations. <i>PNAS</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.1702020114\">https://doi.org/10.1073/pnas.1702020114</a>","mla":"Veller, Carl, et al. “The Red Queen and King in Finite Populations.” <i>PNAS</i>, vol. 114, no. 27, National Academy of Sciences, 2017, pp. E5396–405, doi:<a href=\"https://doi.org/10.1073/pnas.1702020114\">10.1073/pnas.1702020114</a>.","short":"C. Veller, L. Hayward, M. Nowak, C. Hilbe, PNAS 114 (2017) E5396–E5405.","chicago":"Veller, Carl, Laura Hayward, Martin Nowak, and Christian Hilbe. “The Red Queen and King in Finite Populations.” <i>PNAS</i>. National Academy of Sciences, 2017. <a href=\"https://doi.org/10.1073/pnas.1702020114\">https://doi.org/10.1073/pnas.1702020114</a>.","ista":"Veller C, Hayward L, Nowak M, Hilbe C. 2017. The red queen and king in finite populations. PNAS. 114(27), E5396–E5405.","ieee":"C. Veller, L. Hayward, M. Nowak, and C. Hilbe, “The red queen and king in finite populations,” <i>PNAS</i>, vol. 114, no. 27. National Academy of Sciences, pp. E5396–E5405, 2017.","ama":"Veller C, Hayward L, Nowak M, Hilbe C. The red queen and king in finite populations. <i>PNAS</i>. 2017;114(27):E5396-E5405. doi:<a href=\"https://doi.org/10.1073/pnas.1702020114\">10.1073/pnas.1702020114</a>"},"status":"public","date_created":"2018-12-11T11:48:00Z","month":"07","publist_id":"7002","intvolume":"       114","publisher":"National Academy of Sciences","volume":114,"issue":"27"},{"publication_identifier":{"issn":["24700045"]},"scopus_import":1,"date_published":"2017-07-12T00:00:00Z","ec_funded":1,"doi":"10.1103/PhysRevE.96.012404","language":[{"iso":"eng"}],"department":[{"_id":"JoFi"}],"user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","date_updated":"2023-02-23T12:56:35Z","type":"journal_article","oa_version":"Submitted Version","day":"12","intvolume":"        96","publist_id":"6997","date_created":"2018-12-11T11:48:00Z","month":"07","article_number":"012404","status":"public","issue":"1","volume":96,"publisher":"American Institute of Physics","publication":" Physical Review E Statistical Nonlinear and Soft Matter Physics ","title":"Optomechanical proposal for monitoring microtubule mechanical vibrations","oa":1,"_id":"700","project":[{"_id":"258047B6-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"707438","name":"Microwave-to-Optical Quantum Link: Quantum Teleportation and Quantum Illumination with cavity Optomechanics"}],"publication_status":"published","abstract":[{"text":"Microtubules provide the mechanical force required for chromosome separation during mitosis. However, little is known about the dynamic (high-frequency) mechanical properties of microtubules. Here, we theoretically propose to control the vibrations of a doubly clamped microtubule by tip electrodes and to detect its motion via the optomechanical coupling between the vibrational modes of the microtubule and an optical cavity. In the presence of a red-detuned strong pump laser, this coupling leads to optomechanical-induced transparency of an optical probe field, which can be detected with state-of-the art technology. The center frequency and line width of the transparency peak give the resonance frequency and damping rate of the microtubule, respectively, while the height of the peak reveals information about the microtubule-cavity field coupling. Our method opens the new possibilities to gain information about the physical properties of microtubules, which will enhance our capability to design physical cancer treatment protocols as alternatives to chemotherapeutic drugs.","lang":"eng"}],"main_file_link":[{"url":"https://arxiv.org/pdf/1612.07061.pdf","open_access":"1"}],"citation":{"mla":"Barzanjeh, Shabir, et al. “Optomechanical Proposal for Monitoring Microtubule Mechanical Vibrations.” <i> Physical Review E Statistical Nonlinear and Soft Matter Physics </i>, vol. 96, no. 1, 012404, American Institute of Physics, 2017, doi:<a href=\"https://doi.org/10.1103/PhysRevE.96.012404\">10.1103/PhysRevE.96.012404</a>.","apa":"Barzanjeh, S., Salari, V., Tuszynski, J., Cifra, M., &#38; Simon, C. (2017). Optomechanical proposal for monitoring microtubule mechanical vibrations. <i> Physical Review E Statistical Nonlinear and Soft Matter Physics </i>. American Institute of Physics. <a href=\"https://doi.org/10.1103/PhysRevE.96.012404\">https://doi.org/10.1103/PhysRevE.96.012404</a>","ama":"Barzanjeh S, Salari V, Tuszynski J, Cifra M, Simon C. Optomechanical proposal for monitoring microtubule mechanical vibrations. <i> Physical Review E Statistical Nonlinear and Soft Matter Physics </i>. 2017;96(1). doi:<a href=\"https://doi.org/10.1103/PhysRevE.96.012404\">10.1103/PhysRevE.96.012404</a>","ieee":"S. Barzanjeh, V. Salari, J. Tuszynski, M. Cifra, and C. Simon, “Optomechanical proposal for monitoring microtubule mechanical vibrations,” <i> Physical Review E Statistical Nonlinear and Soft Matter Physics </i>, vol. 96, no. 1. American Institute of Physics, 2017.","ista":"Barzanjeh S, Salari V, Tuszynski J, Cifra M, Simon C. 2017. Optomechanical proposal for monitoring microtubule mechanical vibrations.  Physical Review E Statistical Nonlinear and Soft Matter Physics . 96(1), 012404.","chicago":"Barzanjeh, Shabir, Vahid Salari, Jack Tuszynski, Michal Cifra, and Christoph Simon. “Optomechanical Proposal for Monitoring Microtubule Mechanical Vibrations.” <i> Physical Review E Statistical Nonlinear and Soft Matter Physics </i>. American Institute of Physics, 2017. <a href=\"https://doi.org/10.1103/PhysRevE.96.012404\">https://doi.org/10.1103/PhysRevE.96.012404</a>.","short":"S. Barzanjeh, V. Salari, J. Tuszynski, M. Cifra, C. Simon,  Physical Review E Statistical Nonlinear and Soft Matter Physics  96 (2017)."},"author":[{"orcid":"0000-0003-0415-1423","full_name":"Barzanjeh, Shabir","id":"2D25E1F6-F248-11E8-B48F-1D18A9856A87","first_name":"Shabir","last_name":"Barzanjeh"},{"first_name":"Vahid","last_name":"Salari","full_name":"Salari, Vahid"},{"first_name":"Jack","last_name":"Tuszynski","full_name":"Tuszynski, Jack"},{"first_name":"Michal","last_name":"Cifra","full_name":"Cifra, Michal"},{"first_name":"Christoph","last_name":"Simon","full_name":"Simon, Christoph"}],"quality_controlled":"1","year":"2017"},{"language":[{"iso":"eng"}],"department":[{"_id":"UlWa"}],"has_accepted_license":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","day":"14","type":"journal_article","date_updated":"2021-01-12T08:11:28Z","oa_version":"Submitted Version","publication_identifier":{"issn":["10778926"]},"page":"1-44","date_published":"2017-07-14T00:00:00Z","file":[{"content_type":"application/pdf","creator":"system","file_size":544042,"relation":"main_file","date_created":"2018-12-12T10:14:25Z","file_name":"IST-2018-984-v1+1_Patakova_on_the_nonexistence_of_k-reptile_simplices_in_R_3_and_R_4_2017.pdf","checksum":"a431e573e31df13bc0f66de3061006ec","access_level":"open_access","date_updated":"2020-07-14T12:47:47Z","file_id":"5077"}],"ddc":["500"],"oa":1,"_id":"701","publication":"The Electronic Journal of Combinatorics","title":"On the nonexistence of k reptile simplices in ℝ^3 and ℝ^4","publication_status":"published","abstract":[{"lang":"eng","text":"A d-dimensional simplex S is called a k-reptile (or a k-reptile simplex) if it can be tiled by k simplices with disjoint interiors that are all mutually congruent and similar to S. For d = 2, triangular k-reptiles exist for all k of the form a^2, 3a^2 or a^2+b^2 and they have been completely characterized by Snover, Waiveris, and Williams. On the other hand, the only k-reptile simplices that are known for d ≥ 3, have k = m^d, where m is a positive integer. We substantially simplify the proof by Matoušek and the second author that for d = 3, k-reptile tetrahedra can exist only for k = m^3. We then prove a weaker analogue of this result for d = 4 by showing that four-dimensional k-reptile simplices can exist only for k = m^2."}],"quality_controlled":"1","author":[{"first_name":"Jan","last_name":"Kynčl","full_name":"Kynčl, Jan"},{"id":"48B57058-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-3975-1683","full_name":"Patakova, Zuzana","last_name":"Patakova","first_name":"Zuzana"}],"citation":{"apa":"Kynčl, J., &#38; Patakova, Z. (2017). On the nonexistence of k reptile simplices in ℝ^3 and ℝ^4. <i>The Electronic Journal of Combinatorics</i>. International Press.","mla":"Kynčl, Jan, and Zuzana Patakova. “On the Nonexistence of k Reptile Simplices in ℝ^3 and ℝ^4.” <i>The Electronic Journal of Combinatorics</i>, vol. 24, no. 3, International Press, 2017, pp. 1–44.","short":"J. Kynčl, Z. Patakova, The Electronic Journal of Combinatorics 24 (2017) 1–44.","chicago":"Kynčl, Jan, and Zuzana Patakova. “On the Nonexistence of k Reptile Simplices in ℝ^3 and ℝ^4.” <i>The Electronic Journal of Combinatorics</i>. International Press, 2017.","ista":"Kynčl J, Patakova Z. 2017. On the nonexistence of k reptile simplices in ℝ^3 and ℝ^4. The Electronic Journal of Combinatorics. 24(3), 1–44.","ieee":"J. Kynčl and Z. Patakova, “On the nonexistence of k reptile simplices in ℝ^3 and ℝ^4,” <i>The Electronic Journal of Combinatorics</i>, vol. 24, no. 3. International Press, pp. 1–44, 2017.","ama":"Kynčl J, Patakova Z. On the nonexistence of k reptile simplices in ℝ^3 and ℝ^4. <i>The Electronic Journal of Combinatorics</i>. 2017;24(3):1-44."},"year":"2017","publist_id":"6996","intvolume":"        24","status":"public","date_created":"2018-12-11T11:48:00Z","month":"07","volume":24,"issue":"3","pubrep_id":"984","publisher":"International Press","file_date_updated":"2020-07-14T12:47:47Z"},{"publisher":"American Association for the Advancement of Science","page":"eaao0972","issue":"399","volume":9,"date_published":"2017-07-19T00:00:00Z","status":"public","date_created":"2018-12-11T11:48:01Z","month":"07","publist_id":"6993","publication_identifier":{"issn":["19466234"]},"scopus_import":1,"intvolume":"         9","day":"19","year":"2017","date_updated":"2021-01-12T08:11:31Z","type":"journal_article","oa_version":"None","user_id":"4435EBFC-F248-11E8-B48F-1D18A9856A87","author":[{"id":"3E57A680-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-7673-7178","full_name":"Novarino, Gaia","last_name":"Novarino","first_name":"Gaia"}],"quality_controlled":"1","citation":{"apa":"Novarino, G. (2017). The riddle of CHD8 haploinsufficiency in autism spectrum disorder. <i>Science Translational Medicine</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/scitranslmed.aao0972\">https://doi.org/10.1126/scitranslmed.aao0972</a>","mla":"Novarino, Gaia. “The Riddle of CHD8 Haploinsufficiency in Autism Spectrum Disorder.” <i>Science Translational Medicine</i>, vol. 9, no. 399, American Association for the Advancement of Science, 2017, p. eaao0972, doi:<a href=\"https://doi.org/10.1126/scitranslmed.aao0972\">10.1126/scitranslmed.aao0972</a>.","ieee":"G. Novarino, “The riddle of CHD8 haploinsufficiency in autism spectrum disorder,” <i>Science Translational Medicine</i>, vol. 9, no. 399. American Association for the Advancement of Science, p. eaao0972, 2017.","ama":"Novarino G. The riddle of CHD8 haploinsufficiency in autism spectrum disorder. <i>Science Translational Medicine</i>. 2017;9(399):eaao0972. doi:<a href=\"https://doi.org/10.1126/scitranslmed.aao0972\">10.1126/scitranslmed.aao0972</a>","short":"G. Novarino, Science Translational Medicine 9 (2017) eaao0972.","chicago":"Novarino, Gaia. “The Riddle of CHD8 Haploinsufficiency in Autism Spectrum Disorder.” <i>Science Translational Medicine</i>. American Association for the Advancement of Science, 2017. <a href=\"https://doi.org/10.1126/scitranslmed.aao0972\">https://doi.org/10.1126/scitranslmed.aao0972</a>.","ista":"Novarino G. 2017. The riddle of CHD8 haploinsufficiency in autism spectrum disorder. Science Translational Medicine. 9(399), eaao0972."},"publication_status":"published","abstract":[{"lang":"eng","text":"Leading autism-associated mutation in mouse partially mimics human disorder.\r\n\r\n"}],"language":[{"iso":"eng"}],"doi":"10.1126/scitranslmed.aao0972","department":[{"_id":"GaNo"}],"_id":"702","publication":"Science Translational Medicine","title":"The riddle of CHD8 haploinsufficiency in autism spectrum disorder"},{"oa_version":"Published Version","date_updated":"2024-03-25T23:30:14Z","type":"journal_article","day":"25","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","has_accepted_license":"1","department":[{"_id":"CaGu"}],"doi":"10.7554/eLife.25100","language":[{"iso":"eng"}],"file":[{"date_created":"2018-12-12T10:12:54Z","relation":"main_file","content_type":"application/pdf","creator":"system","file_size":2092088,"file_id":"4975","date_updated":"2020-07-14T12:47:48Z","access_level":"open_access","file_name":"IST-2017-890-v1+1_elife-25100-v1.pdf","checksum":"6b908b5db9f61f6820ebd7f8fa815571"},{"date_created":"2018-12-12T10:12:55Z","relation":"main_file","content_type":"application/pdf","creator":"system","file_size":3428681,"file_id":"4976","date_updated":"2020-07-14T12:47:48Z","access_level":"open_access","checksum":"ca21530389b720243552678125fdba35","file_name":"IST-2017-890-v1+2_elife-25100-figures-v1.pdf"}],"date_published":"2017-07-25T00:00:00Z","scopus_import":1,"publication_identifier":{"issn":["2050084X"]},"tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"year":"2017","citation":{"mla":"Steinrück, Magdalena, and Calin C. Guet. “Complex Chromosomal Neighborhood Effects Determine the Adaptive Potential of a Gene under Selection.” <i>ELife</i>, vol. 6, e25100, eLife Sciences Publications, 2017, doi:<a href=\"https://doi.org/10.7554/eLife.25100\">10.7554/eLife.25100</a>.","apa":"Steinrück, M., &#38; Guet, C. C. (2017). Complex chromosomal neighborhood effects determine the adaptive potential of a gene under selection. <i>ELife</i>. eLife Sciences Publications. <a href=\"https://doi.org/10.7554/eLife.25100\">https://doi.org/10.7554/eLife.25100</a>","ista":"Steinrück M, Guet CC. 2017. Complex chromosomal neighborhood effects determine the adaptive potential of a gene under selection. eLife. 6, e25100.","chicago":"Steinrück, Magdalena, and Calin C Guet. “Complex Chromosomal Neighborhood Effects Determine the Adaptive Potential of a Gene under Selection.” <i>ELife</i>. eLife Sciences Publications, 2017. <a href=\"https://doi.org/10.7554/eLife.25100\">https://doi.org/10.7554/eLife.25100</a>.","short":"M. Steinrück, C.C. Guet, ELife 6 (2017).","ama":"Steinrück M, Guet CC. Complex chromosomal neighborhood effects determine the adaptive potential of a gene under selection. <i>eLife</i>. 2017;6. doi:<a href=\"https://doi.org/10.7554/eLife.25100\">10.7554/eLife.25100</a>","ieee":"M. Steinrück and C. C. Guet, “Complex chromosomal neighborhood effects determine the adaptive potential of a gene under selection,” <i>eLife</i>, vol. 6. eLife Sciences Publications, 2017."},"quality_controlled":"1","author":[{"full_name":"Steinrück, Magdalena","orcid":"0000-0003-1229-9719","id":"2C023F40-F248-11E8-B48F-1D18A9856A87","last_name":"Steinrück","first_name":"Magdalena"},{"orcid":"0000-0001-6220-2052","full_name":"Guet, Calin C","id":"47F8433E-F248-11E8-B48F-1D18A9856A87","first_name":"Calin C","last_name":"Guet"}],"abstract":[{"lang":"eng","text":"How the organization of genes on a chromosome shapes adaptation is essential for understanding evolutionary paths. Here, we investigate how adaptation to rapidly increasing levels of antibiotic depends on the chromosomal neighborhood of a drug-resistance gene inserted at different positions of the Escherichia coli chromosome. Using a dual-fluorescence reporter that allows us to distinguish gene amplifications from other up-mutations, we track in real-time adaptive changes in expression of the drug-resistance gene. We find that the relative contribution of several mutation types differs systematically between loci due to properties of neighboring genes: essentiality, expression, orientation, termination, and presence of duplicates. These properties determine rate and fitness effects of gene amplification, deletions, and mutations compromising transcriptional termination. Thus, the adaptive potential of a gene under selection is a system-property with a complex genetic basis that is specific for each chromosomal locus, and it can be inferred from detailed functional and genomic data."}],"publication_status":"published","publication":"eLife","title":"Complex chromosomal neighborhood effects determine the adaptive potential of a gene under selection","_id":"704","ddc":["576"],"related_material":{"record":[{"status":"public","relation":"popular_science","id":"5564"},{"id":"26","relation":"dissertation_contains","status":"public"}]},"oa":1,"file_date_updated":"2020-07-14T12:47:48Z","publisher":"eLife Sciences Publications","pubrep_id":"890","volume":6,"month":"07","date_created":"2018-12-11T11:48:01Z","article_number":"e25100","status":"public","intvolume":"         6","publist_id":"6990"},{"intvolume":"        22","publist_id":"6987","publication_identifier":{"issn":["13569597"]},"scopus_import":1,"date_created":"2018-12-11T11:48:02Z","month":"08","status":"public","date_published":"2017-08-01T00:00:00Z","issue":"8","volume":22,"page":"715 - 722","publisher":"Wiley-Blackwell","title":"Roles of afadin in functional differentiations of hippocampal mossy fiber synapse","publication":"Genes to Cells","language":[{"iso":"eng"}],"doi":"10.1111/gtc.12508","department":[{"_id":"PeJo"}],"_id":"706","publication_status":"published","abstract":[{"text":"A hippocampal mossy fiber synapse has a complex structure and is implicated in learning and memory. In this synapse, the mossy fiber boutons attach to the dendritic shaft by puncta adherentia junctions and wrap around a multiply-branched spine, forming synaptic junctions. We have recently shown using transmission electron microscopy, immunoelectron microscopy and serial block face-scanning electron microscopy that atypical puncta adherentia junctions are formed in the afadin-deficient mossy fiber synapse and that the complexity of postsynaptic spines and mossy fiber boutons, the number of spine heads, the area of postsynaptic densities and the density of synaptic vesicles docked to active zones are decreased in the afadin-deficient synapse. We investigated here the roles of afadin in the functional differentiations of the mossy fiber synapse using the afadin-deficient mice. The electrophysiological studies showed that both the release probability of glutamate and the postsynaptic responsiveness to glutamate were markedly reduced, but not completely lost, in the afadin-deficient mossy fiber synapse, whereas neither long-term potentiation nor long-term depression was affected. These results indicate that afadin plays roles in the functional differentiations of the presynapse and the postsynapse of the hippocampal mossy fiber synapse.","lang":"eng"}],"citation":{"ista":"Geng X, Maruo T, Mandai K, Supriyanto I, Miyata M, Sakakibara S, Mizoguchi A, Takai Y, Mori M. 2017. Roles of afadin in functional differentiations of hippocampal mossy fiber synapse. Genes to Cells. 22(8), 715–722.","short":"X. Geng, T. Maruo, K. Mandai, I. Supriyanto, M. Miyata, S. Sakakibara, A. Mizoguchi, Y. Takai, M. Mori, Genes to Cells 22 (2017) 715–722.","chicago":"Geng, Xiaoqi, Tomohiko Maruo, Kenji Mandai, Irwan Supriyanto, Muneaki Miyata, Shotaro Sakakibara, Akira Mizoguchi, Yoshimi Takai, and Masahiro Mori. “Roles of Afadin in Functional Differentiations of Hippocampal Mossy Fiber Synapse.” <i>Genes to Cells</i>. Wiley-Blackwell, 2017. <a href=\"https://doi.org/10.1111/gtc.12508\">https://doi.org/10.1111/gtc.12508</a>.","ama":"Geng X, Maruo T, Mandai K, et al. Roles of afadin in functional differentiations of hippocampal mossy fiber synapse. <i>Genes to Cells</i>. 2017;22(8):715-722. doi:<a href=\"https://doi.org/10.1111/gtc.12508\">10.1111/gtc.12508</a>","ieee":"X. Geng <i>et al.</i>, “Roles of afadin in functional differentiations of hippocampal mossy fiber synapse,” <i>Genes to Cells</i>, vol. 22, no. 8. Wiley-Blackwell, pp. 715–722, 2017.","apa":"Geng, X., Maruo, T., Mandai, K., Supriyanto, I., Miyata, M., Sakakibara, S., … Mori, M. (2017). Roles of afadin in functional differentiations of hippocampal mossy fiber synapse. <i>Genes to Cells</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1111/gtc.12508\">https://doi.org/10.1111/gtc.12508</a>","mla":"Geng, Xiaoqi, et al. “Roles of Afadin in Functional Differentiations of Hippocampal Mossy Fiber Synapse.” <i>Genes to Cells</i>, vol. 22, no. 8, Wiley-Blackwell, 2017, pp. 715–22, doi:<a href=\"https://doi.org/10.1111/gtc.12508\">10.1111/gtc.12508</a>."},"user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","quality_controlled":"1","author":[{"id":"3395256A-F248-11E8-B48F-1D18A9856A87","full_name":"Geng, Xiaoqi","last_name":"Geng","first_name":"Xiaoqi"},{"first_name":"Tomohiko","last_name":"Maruo","full_name":"Maruo, Tomohiko"},{"first_name":"Kenji","last_name":"Mandai","full_name":"Mandai, Kenji"},{"full_name":"Supriyanto, Irwan","last_name":"Supriyanto","first_name":"Irwan"},{"first_name":"Muneaki","last_name":"Miyata","full_name":"Miyata, Muneaki"},{"full_name":"Sakakibara, Shotaro","first_name":"Shotaro","last_name":"Sakakibara"},{"last_name":"Mizoguchi","first_name":"Akira","full_name":"Mizoguchi, Akira"},{"full_name":"Takai, Yoshimi","last_name":"Takai","first_name":"Yoshimi"},{"last_name":"Mori","first_name":"Masahiro","full_name":"Mori, Masahiro"}],"date_updated":"2021-01-12T08:11:37Z","type":"journal_article","oa_version":"None","day":"01","year":"2017"}]