[{"status":"public","_id":"11898","intvolume":"       779","date_published":"2019-08-02T00:00:00Z","year":"2019","extern":"1","date_updated":"2022-09-09T11:29:04Z","oa_version":"Preprint","volume":779,"quality_controlled":"1","language":[{"iso":"eng"}],"day":"02","type":"journal_article","oa":1,"publisher":"Elsevier","doi":"10.1016/j.tcs.2019.01.043","publication":"Theoretical Computer Science","title":"New amortized cell-probe lower bounds for dynamic problems","arxiv":1,"citation":{"ista":"Bhattacharya S, Henzinger MH, Neumann S. 2019. New amortized cell-probe lower bounds for dynamic problems. Theoretical Computer Science. 779, 72–87.","mla":"Bhattacharya, Sayan, et al. “New Amortized Cell-Probe Lower Bounds for Dynamic Problems.” <i>Theoretical Computer Science</i>, vol. 779, Elsevier, 2019, pp. 72–87, doi:<a href=\"https://doi.org/10.1016/j.tcs.2019.01.043\">10.1016/j.tcs.2019.01.043</a>.","short":"S. Bhattacharya, M.H. Henzinger, S. Neumann, Theoretical Computer Science 779 (2019) 72–87.","ama":"Bhattacharya S, Henzinger MH, Neumann S. New amortized cell-probe lower bounds for dynamic problems. <i>Theoretical Computer Science</i>. 2019;779:72-87. doi:<a href=\"https://doi.org/10.1016/j.tcs.2019.01.043\">10.1016/j.tcs.2019.01.043</a>","ieee":"S. Bhattacharya, M. H. Henzinger, and S. Neumann, “New amortized cell-probe lower bounds for dynamic problems,” <i>Theoretical Computer Science</i>, vol. 779. Elsevier, pp. 72–87, 2019.","apa":"Bhattacharya, S., Henzinger, M. H., &#38; Neumann, S. (2019). New amortized cell-probe lower bounds for dynamic problems. <i>Theoretical Computer Science</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.tcs.2019.01.043\">https://doi.org/10.1016/j.tcs.2019.01.043</a>","chicago":"Bhattacharya, Sayan, Monika H Henzinger, and Stefan Neumann. “New Amortized Cell-Probe Lower Bounds for Dynamic Problems.” <i>Theoretical Computer Science</i>. Elsevier, 2019. <a href=\"https://doi.org/10.1016/j.tcs.2019.01.043\">https://doi.org/10.1016/j.tcs.2019.01.043</a>."},"month":"08","article_processing_charge":"No","scopus_import":"1","main_file_link":[{"url":"https://arxiv.org/abs/1902.02304","open_access":"1"}],"abstract":[{"text":"We build upon the recent papers by Weinstein and Yu (FOCS'16), Larsen (FOCS'12), and Clifford et al. (FOCS'15) to present a general framework that gives amortized lower bounds on the update and query times of dynamic data structures. Using our framework, we present two concrete results.\r\n(1) For the dynamic polynomial evaluation problem, where the polynomial is defined over a finite field of size n1+Ω(1) and has degree n, any dynamic data structure must either have an amortized update time of Ω((lgn/lglgn)2) or an amortized query time of Ω((lgn/lglgn)2).\r\n(2) For the dynamic online matrix vector multiplication problem, where we get an n×n matrix whose entires are drawn from a finite field of size nΘ(1), any dynamic data structure must either have an amortized update time of Ω((lgn/lglgn)2) or an amortized query time of Ω(n⋅(lgn/lglgn)2).\r\nFor these two problems, the previous works by Larsen (FOCS'12) and Clifford et al. (FOCS'15) gave the same lower bounds, but only for worst case update and query times. Our bounds match the highest unconditional lower bounds known till date for any dynamic problem in the cell-probe model.","lang":"eng"}],"date_created":"2022-08-17T09:02:15Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","external_id":{"arxiv":["1902.02304"]},"page":"72-87","author":[{"first_name":"Sayan","last_name":"Bhattacharya","full_name":"Bhattacharya, Sayan"},{"orcid":"0000-0002-5008-6530","first_name":"Monika H","id":"540c9bbd-f2de-11ec-812d-d04a5be85630","full_name":"Henzinger, Monika H","last_name":"Henzinger"},{"full_name":"Neumann, Stefan","last_name":"Neumann","first_name":"Stefan"}],"publication_status":"published","article_type":"original","publication_identifier":{"issn":["0304-3975"]}},{"date_created":"2022-08-24T10:50:19Z","issue":"28","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","page":"9575-9580","external_id":{"pmid":["31050132"]},"publication_status":"published","author":[{"orcid":"0000-0001-8689-388X","first_name":"Bartholomäus","last_name":"Pieber","id":"93e5e5b2-0da6-11ed-8a41-af589a024726","full_name":"Pieber, Bartholomäus"},{"last_name":"Malik","full_name":"Malik, Jamal A.","first_name":"Jamal A."},{"first_name":"Cristian","last_name":"Cavedon","full_name":"Cavedon, Cristian"},{"first_name":"Sebastian","last_name":"Gisbertz","full_name":"Gisbertz, Sebastian"},{"last_name":"Savateev","full_name":"Savateev, Aleksandr","first_name":"Aleksandr"},{"first_name":"Daniel","full_name":"Cruz, Daniel","last_name":"Cruz"},{"last_name":"Heil","full_name":"Heil, Tobias","first_name":"Tobias"},{"first_name":"Guigang","full_name":"Zhang, Guigang","last_name":"Zhang"},{"full_name":"Seeberger, Peter H.","last_name":"Seeberger","first_name":"Peter H."}],"publication_identifier":{"issn":["1433-7851"],"eissn":["1521-3773"]},"article_type":"letter_note","month":"07","citation":{"apa":"Pieber, B., Malik, J. A., Cavedon, C., Gisbertz, S., Savateev, A., Cruz, D., … Seeberger, P. H. (2019). Semi‐heterogeneous dual nickel/photocatalysis using carbon nitrides: Esterification of carboxylic acids with aryl halides. <i>Angewandte Chemie International Edition</i>. Wiley. <a href=\"https://doi.org/10.1002/anie.201902785\">https://doi.org/10.1002/anie.201902785</a>","ieee":"B. Pieber <i>et al.</i>, “Semi‐heterogeneous dual nickel/photocatalysis using carbon nitrides: Esterification of carboxylic acids with aryl halides,” <i>Angewandte Chemie International Edition</i>, vol. 58, no. 28. Wiley, pp. 9575–9580, 2019.","chicago":"Pieber, Bartholomäus, Jamal A. Malik, Cristian Cavedon, Sebastian Gisbertz, Aleksandr Savateev, Daniel Cruz, Tobias Heil, Guigang Zhang, and Peter H. Seeberger. “Semi‐heterogeneous Dual Nickel/Photocatalysis Using Carbon Nitrides: Esterification of Carboxylic Acids with Aryl Halides.” <i>Angewandte Chemie International Edition</i>. Wiley, 2019. <a href=\"https://doi.org/10.1002/anie.201902785\">https://doi.org/10.1002/anie.201902785</a>.","short":"B. Pieber, J.A. Malik, C. Cavedon, S. Gisbertz, A. Savateev, D. Cruz, T. Heil, G. Zhang, P.H. Seeberger, Angewandte Chemie International Edition 58 (2019) 9575–9580.","ista":"Pieber B, Malik JA, Cavedon C, Gisbertz S, Savateev A, Cruz D, Heil T, Zhang G, Seeberger PH. 2019. Semi‐heterogeneous dual nickel/photocatalysis using carbon nitrides: Esterification of carboxylic acids with aryl halides. Angewandte Chemie International Edition. 58(28), 9575–9580.","mla":"Pieber, Bartholomäus, et al. “Semi‐heterogeneous Dual Nickel/Photocatalysis Using Carbon Nitrides: Esterification of Carboxylic Acids with Aryl Halides.” <i>Angewandte Chemie International Edition</i>, vol. 58, no. 28, Wiley, 2019, pp. 9575–80, doi:<a href=\"https://doi.org/10.1002/anie.201902785\">10.1002/anie.201902785</a>.","ama":"Pieber B, Malik JA, Cavedon C, et al. Semi‐heterogeneous dual nickel/photocatalysis using carbon nitrides: Esterification of carboxylic acids with aryl halides. <i>Angewandte Chemie International Edition</i>. 2019;58(28):9575-9580. doi:<a href=\"https://doi.org/10.1002/anie.201902785\">10.1002/anie.201902785</a>"},"article_processing_charge":"No","scopus_import":"1","abstract":[{"lang":"eng","text":"Cross-coupling reactions mediated by dual nickel/photocatalysis are synthetically attractive but rely mainly on expensive, non-recyclable noble-metal complexes as photocatalysts. Heterogeneous semiconductors, which are commonly used for artificial photosynthesis and wastewater treatment, are a sustainable alternative. Graphitic carbon nitrides, a class of metal-free polymers that can be easily prepared from bulk chemicals, are heterogeneous semiconductors with high potential for photocatalytic organic transformations. Here, we demonstrate that graphitic carbon nitrides in combination with nickel catalysis can induce selective C−O cross-couplings of carboxylic acids with aryl halides, yielding the respective aryl esters in excellent yield and selectivity. The heterogeneous organic photocatalyst exhibits a broad substrate scope, is able to harvest green light, and can be recycled multiple times. In situ FTIR was used to track the reaction progress to study this transformation at different irradiation wavelengths and reaction scales."}],"quality_controlled":"1","day":"08","type":"journal_article","language":[{"iso":"eng"}],"publication":"Angewandte Chemie International Edition","publisher":"Wiley","doi":"10.1002/anie.201902785","title":"Semi‐heterogeneous dual nickel/photocatalysis using carbon nitrides: Esterification of carboxylic acids with aryl halides","pmid":1,"_id":"11957","intvolume":"        58","status":"public","year":"2019","date_published":"2019-07-08T00:00:00Z","extern":"1","oa_version":"None","volume":58,"date_updated":"2023-02-21T10:09:16Z"},{"extern":"1","date_updated":"2023-02-21T10:10:19Z","volume":21,"oa_version":"Published Version","status":"public","_id":"11982","intvolume":"        21","date_published":"2019-07-05T00:00:00Z","year":"2019","doi":"10.1021/acs.orglett.9b01957","publisher":"American Chemical Society","publication":"Organic Letters","title":"Semiheterogeneous dual nickel/photocatalytic (thio)etherification using carbon nitrides","pmid":1,"quality_controlled":"1","language":[{"iso":"eng"}],"day":"05","type":"journal_article","oa":1,"scopus_import":"1","main_file_link":[{"url":"https://doi.org/10.1021/acs.orglett.9b01957","open_access":"1"}],"abstract":[{"text":"A carbon nitride material can be combined with homogeneous nickel catalysts for light-mediated cross-couplings of aryl bromides with alcohols under mild conditions. The metal-free heterogeneous semiconductor is fully recyclable and couples a broad range of electron-poor aryl bromides with primary and secondary alcohols as well as water. The application for intramolecular reactions and the synthesis of active pharmaceutical ingredients was demonstrated. The catalytic protocol is applicable for the coupling of aryl iodides with thiols as well.","lang":"eng"}],"month":"07","citation":{"mla":"Cavedon, Cristian, et al. “Semiheterogeneous Dual Nickel/Photocatalytic (Thio)Etherification Using Carbon Nitrides.” <i>Organic Letters</i>, vol. 21, no. 13, American Chemical Society, 2019, pp. 5331–34, doi:<a href=\"https://doi.org/10.1021/acs.orglett.9b01957\">10.1021/acs.orglett.9b01957</a>.","short":"C. Cavedon, A. Madani, P.H. Seeberger, B. Pieber, Organic Letters 21 (2019) 5331–5334.","ista":"Cavedon C, Madani A, Seeberger PH, Pieber B. 2019. Semiheterogeneous dual nickel/photocatalytic (thio)etherification using carbon nitrides. Organic Letters. 21(13), 5331–5334.","ama":"Cavedon C, Madani A, Seeberger PH, Pieber B. Semiheterogeneous dual nickel/photocatalytic (thio)etherification using carbon nitrides. <i>Organic Letters</i>. 2019;21(13):5331-5334. doi:<a href=\"https://doi.org/10.1021/acs.orglett.9b01957\">10.1021/acs.orglett.9b01957</a>","apa":"Cavedon, C., Madani, A., Seeberger, P. H., &#38; Pieber, B. (2019). Semiheterogeneous dual nickel/photocatalytic (thio)etherification using carbon nitrides. <i>Organic Letters</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acs.orglett.9b01957\">https://doi.org/10.1021/acs.orglett.9b01957</a>","ieee":"C. Cavedon, A. Madani, P. H. Seeberger, and B. Pieber, “Semiheterogeneous dual nickel/photocatalytic (thio)etherification using carbon nitrides,” <i>Organic Letters</i>, vol. 21, no. 13. American Chemical Society, pp. 5331–5334, 2019.","chicago":"Cavedon, Cristian, Amiera Madani, Peter H. Seeberger, and Bartholomäus Pieber. “Semiheterogeneous Dual Nickel/Photocatalytic (Thio)Etherification Using Carbon Nitrides.” <i>Organic Letters</i>. American Chemical Society, 2019. <a href=\"https://doi.org/10.1021/acs.orglett.9b01957\">https://doi.org/10.1021/acs.orglett.9b01957</a>."},"article_processing_charge":"No","author":[{"first_name":"Cristian","full_name":"Cavedon, Cristian","last_name":"Cavedon"},{"full_name":"Madani, Amiera","last_name":"Madani","first_name":"Amiera"},{"first_name":"Peter H.","last_name":"Seeberger","full_name":"Seeberger, Peter H."},{"orcid":"0000-0001-8689-388X","first_name":"Bartholomäus","last_name":"Pieber","full_name":"Pieber, Bartholomäus","id":"93e5e5b2-0da6-11ed-8a41-af589a024726"}],"publication_status":"published","article_type":"letter_note","publication_identifier":{"issn":["1523-7060"],"eissn":["1523-7052"]},"date_created":"2022-08-25T11:18:00Z","issue":"13","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","external_id":{"pmid":["31247752"]},"page":"5331-5334"},{"publication_identifier":{"eissn":["1520-586X"],"issn":["1083-6160"]},"article_type":"letter_note","publication_status":"published","author":[{"first_name":"Mónica","last_name":"Guberman","full_name":"Guberman, Mónica"},{"orcid":"0000-0001-8689-388X","first_name":"Bartholomäus","last_name":"Pieber","id":"93e5e5b2-0da6-11ed-8a41-af589a024726","full_name":"Pieber, Bartholomäus"},{"first_name":"Peter H.","last_name":"Seeberger","full_name":"Seeberger, Peter H."}],"page":"2764-2770","date_created":"2022-08-25T11:30:33Z","issue":"12","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1021/acs.oprd.9b00456"}],"abstract":[{"text":"Differentially protected galactosamine building blocks are key components for the synthesis of human and bacterial oligosaccharides. The azidophenylselenylation of 3,4,6-tri-O-acetyl-d-galactal provides straightforward access to the corresponding 2-nitrogenated glycoside. Poor reproducibility and the use of azides that lead to the formation of potentially explosive and toxic species limit the scalability of this reaction and render it a bottleneck for carbohydrate synthesis. Here, we present a method for the safe, efficient, and reliable azidophenylselenylation of 3,4,6-tri-O-acetyl-d-galactal at room temperature, using continuous flow chemistry. Careful analysis of the transformation resulted in reaction conditions that produce minimal side products while the reaction time was reduced drastically when compared to batch reactions. The flow setup is readily scalable to process 5 mmol of galactal in 3 h, producing 1.2 mmol/h of product.","lang":"eng"}],"scopus_import":"1","article_processing_charge":"No","month":"12","citation":{"ieee":"M. Guberman, B. Pieber, and P. H. Seeberger, “Safe and scalable continuous flow azidophenylselenylation of galactal to prepare galactosamine building blocks,” <i>Organic Process Research and Development</i>, vol. 23, no. 12. American Chemical Society, pp. 2764–2770, 2019.","apa":"Guberman, M., Pieber, B., &#38; Seeberger, P. H. (2019). Safe and scalable continuous flow azidophenylselenylation of galactal to prepare galactosamine building blocks. <i>Organic Process Research and Development</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acs.oprd.9b00456\">https://doi.org/10.1021/acs.oprd.9b00456</a>","chicago":"Guberman, Mónica, Bartholomäus Pieber, and Peter H. Seeberger. “Safe and Scalable Continuous Flow Azidophenylselenylation of Galactal to Prepare Galactosamine Building Blocks.” <i>Organic Process Research and Development</i>. American Chemical Society, 2019. <a href=\"https://doi.org/10.1021/acs.oprd.9b00456\">https://doi.org/10.1021/acs.oprd.9b00456</a>.","short":"M. Guberman, B. Pieber, P.H. Seeberger, Organic Process Research and Development 23 (2019) 2764–2770.","ama":"Guberman M, Pieber B, Seeberger PH. Safe and scalable continuous flow azidophenylselenylation of galactal to prepare galactosamine building blocks. <i>Organic Process Research and Development</i>. 2019;23(12):2764-2770. doi:<a href=\"https://doi.org/10.1021/acs.oprd.9b00456\">10.1021/acs.oprd.9b00456</a>","ista":"Guberman M, Pieber B, Seeberger PH. 2019. Safe and scalable continuous flow azidophenylselenylation of galactal to prepare galactosamine building blocks. Organic Process Research and Development. 23(12), 2764–2770.","mla":"Guberman, Mónica, et al. “Safe and Scalable Continuous Flow Azidophenylselenylation of Galactal to Prepare Galactosamine Building Blocks.” <i>Organic Process Research and Development</i>, vol. 23, no. 12, American Chemical Society, 2019, pp. 2764–70, doi:<a href=\"https://doi.org/10.1021/acs.oprd.9b00456\">10.1021/acs.oprd.9b00456</a>."},"title":"Safe and scalable continuous flow azidophenylselenylation of galactal to prepare galactosamine building blocks","publication":"Organic Process Research and Development","doi":"10.1021/acs.oprd.9b00456","publisher":"American Chemical Society","day":"20","oa":1,"type":"journal_article","language":[{"iso":"eng"}],"quality_controlled":"1","volume":23,"oa_version":"Published Version","date_updated":"2023-02-21T10:10:23Z","extern":"1","year":"2019","date_published":"2019-12-20T00:00:00Z","_id":"11984","intvolume":"        23","status":"public"},{"page":"2676-2686.e3","keyword":["General Agricultural and Biological Sciences","General Biochemistry","Genetics and Molecular Biology"],"external_id":{"pmid":["31378616"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2023-01-16T09:16:33Z","issue":"16","publication_identifier":{"issn":["0960-9822"]},"article_type":"original","publication_status":"published","author":[{"full_name":"Lawrence, Emma J.","last_name":"Lawrence","first_name":"Emma J."},{"first_name":"Hongbo","last_name":"Gao","full_name":"Gao, Hongbo"},{"last_name":"Tock","full_name":"Tock, Andrew J.","first_name":"Andrew J."},{"last_name":"Lambing","full_name":"Lambing, Christophe","first_name":"Christophe"},{"first_name":"Alexander R.","full_name":"Blackwell, Alexander R.","last_name":"Blackwell"},{"orcid":"0000-0002-4008-1234","last_name":"Feng","id":"e0164712-22ee-11ed-b12a-d80fcdf35958","full_name":"Feng, Xiaoqi","first_name":"Xiaoqi"},{"last_name":"Henderson","full_name":"Henderson, Ian R.","first_name":"Ian R."}],"article_processing_charge":"No","citation":{"ista":"Lawrence EJ, Gao H, Tock AJ, Lambing C, Blackwell AR, Feng X, Henderson IR. 2019. Natural variation in TBP-ASSOCIATED FACTOR 4b controls meiotic crossover and germline transcription in Arabidopsis. Current Biology. 29(16), 2676–2686.e3.","ama":"Lawrence EJ, Gao H, Tock AJ, et al. Natural variation in TBP-ASSOCIATED FACTOR 4b controls meiotic crossover and germline transcription in Arabidopsis. <i>Current Biology</i>. 2019;29(16):2676-2686.e3. doi:<a href=\"https://doi.org/10.1016/j.cub.2019.06.084\">10.1016/j.cub.2019.06.084</a>","mla":"Lawrence, Emma J., et al. “Natural Variation in TBP-ASSOCIATED FACTOR 4b Controls Meiotic Crossover and Germline Transcription in Arabidopsis.” <i>Current Biology</i>, vol. 29, no. 16, Elsevier BV, 2019, p. 2676–2686.e3, doi:<a href=\"https://doi.org/10.1016/j.cub.2019.06.084\">10.1016/j.cub.2019.06.084</a>.","short":"E.J. Lawrence, H. Gao, A.J. Tock, C. Lambing, A.R. Blackwell, X. Feng, I.R. Henderson, Current Biology 29 (2019) 2676–2686.e3.","ieee":"E. J. Lawrence <i>et al.</i>, “Natural variation in TBP-ASSOCIATED FACTOR 4b controls meiotic crossover and germline transcription in Arabidopsis,” <i>Current Biology</i>, vol. 29, no. 16. Elsevier BV, p. 2676–2686.e3, 2019.","apa":"Lawrence, E. J., Gao, H., Tock, A. J., Lambing, C., Blackwell, A. R., Feng, X., &#38; Henderson, I. R. (2019). Natural variation in TBP-ASSOCIATED FACTOR 4b controls meiotic crossover and germline transcription in Arabidopsis. <i>Current Biology</i>. Elsevier BV. <a href=\"https://doi.org/10.1016/j.cub.2019.06.084\">https://doi.org/10.1016/j.cub.2019.06.084</a>","chicago":"Lawrence, Emma J., Hongbo Gao, Andrew J. Tock, Christophe Lambing, Alexander R. Blackwell, Xiaoqi Feng, and Ian R. Henderson. “Natural Variation in TBP-ASSOCIATED FACTOR 4b Controls Meiotic Crossover and Germline Transcription in Arabidopsis.” <i>Current Biology</i>. Elsevier BV, 2019. <a href=\"https://doi.org/10.1016/j.cub.2019.06.084\">https://doi.org/10.1016/j.cub.2019.06.084</a>."},"month":"08","department":[{"_id":"XiFe"}],"abstract":[{"text":"Meiotic crossover frequency varies within genomes, which influences genetic diversity and adaptation. In turn, genetic variation within populations can act to modify crossover frequency in cis and trans. To identify genetic variation that controls meiotic crossover frequency, we screened Arabidopsis accessions using fluorescent recombination reporters. We mapped a genetic modifier of crossover frequency in Col × Bur populations of Arabidopsis to a premature stop codon within TBP-ASSOCIATED FACTOR 4b (TAF4b), which encodes a subunit of the RNA polymerase II general transcription factor TFIID. The Arabidopsis taf4b mutation is a rare variant found in the British Isles, originating in South-West Ireland. Using genetics, genomics, and immunocytology, we demonstrate a genome-wide decrease in taf4b crossovers, with strongest reduction in the sub-telomeric regions. Using RNA sequencing (RNA-seq) from purified meiocytes, we show that TAF4b expression is meiocyte enriched, whereas its paralog TAF4 is broadly expressed. Consistent with the role of TFIID in promoting gene expression, RNA-seq of wild-type and taf4b meiocytes identified widespread transcriptional changes, including in genes that regulate the meiotic cell cycle and recombination. Therefore, TAF4b duplication is associated with acquisition of meiocyte-specific expression and promotion of germline transcription, which act directly or indirectly to elevate crossovers. This identifies a novel mode of meiotic recombination control via a general transcription factor.","lang":"eng"}],"acknowledgement":"We thank Gregory Copenhaver (University of North Carolina), Avraham Levy (The Weizmann Institute), and Scott Poethig (University of Pennsylvania) for FTLs; Piotr Ziolkowski for Col-420/Bur seed; Sureshkumar Balasubramanian\r\n(Monash University) for providing British and Irish Arabidopsis accessions; Mathilde Grelon (INRA, Versailles) for providing the MLH1 antibody; and the Gurdon Institute for access to microscopes. This work was supported by a BBSRC DTP studentship (E.J.L.), European Research Area Network for Coordinating Action in Plant Sciences/BBSRC ‘‘DeCOP’’ (BB/M004937/1; C.L.), a BBSRC David Phillips Fellowship (BB/L025043/1; H.G. and X.F.), the European Research Council (CoG ‘‘SynthHotspot,’’ A.J.T., C.L., and I.R.H.; StG ‘‘SexMeth,’’ X.F.), and a Sainsbury Charitable Foundation Studentship (A.R.B.).","scopus_import":"1","type":"journal_article","day":"19","language":[{"iso":"eng"}],"quality_controlled":"1","pmid":1,"title":"Natural variation in TBP-ASSOCIATED FACTOR 4b controls meiotic crossover and germline transcription in Arabidopsis","publication":"Current Biology","doi":"10.1016/j.cub.2019.06.084","publisher":"Elsevier BV","year":"2019","date_published":"2019-08-19T00:00:00Z","intvolume":"        29","_id":"12190","status":"public","oa_version":"None","volume":29,"date_updated":"2023-05-08T10:54:54Z","extern":"1"},{"external_id":{"unknown":["31135340"]},"keyword":["General Immunology and Microbiology","General Biochemistry","Genetics and Molecular Biology","General Medicine","General Neuroscience"],"date_created":"2023-01-16T09:17:21Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"issn":["2050-084X"]},"article_type":"original","publication_status":"published","author":[{"last_name":"He","full_name":"He, Shengbo","first_name":"Shengbo"},{"full_name":"Vickers, Martin","last_name":"Vickers","first_name":"Martin"},{"first_name":"Jingyi","full_name":"Zhang, Jingyi","last_name":"Zhang"},{"full_name":"Feng, Xiaoqi","id":"e0164712-22ee-11ed-b12a-d80fcdf35958","last_name":"Feng","first_name":"Xiaoqi","orcid":"0000-0002-4008-1234"}],"article_number":"42530","article_processing_charge":"No","department":[{"_id":"XiFe"}],"month":"05","citation":{"ama":"He S, Vickers M, Zhang J, Feng X. Natural depletion of histone H1 in sex cells causes DNA demethylation, heterochromatin decondensation and transposon activation. <i>eLife</i>. 2019;8. doi:<a href=\"https://doi.org/10.7554/elife.42530\">10.7554/elife.42530</a>","mla":"He, Shengbo, et al. “Natural Depletion of Histone H1 in Sex Cells Causes DNA Demethylation, Heterochromatin Decondensation and Transposon Activation.” <i>ELife</i>, vol. 8, 42530, eLife Sciences Publications, Ltd, 2019, doi:<a href=\"https://doi.org/10.7554/elife.42530\">10.7554/elife.42530</a>.","ista":"He S, Vickers M, Zhang J, Feng X. 2019. Natural depletion of histone H1 in sex cells causes DNA demethylation, heterochromatin decondensation and transposon activation. eLife. 8, 42530.","short":"S. He, M. Vickers, J. Zhang, X. Feng, ELife 8 (2019).","chicago":"He, Shengbo, Martin Vickers, Jingyi Zhang, and Xiaoqi Feng. “Natural Depletion of Histone H1 in Sex Cells Causes DNA Demethylation, Heterochromatin Decondensation and Transposon Activation.” <i>ELife</i>. eLife Sciences Publications, Ltd, 2019. <a href=\"https://doi.org/10.7554/elife.42530\">https://doi.org/10.7554/elife.42530</a>.","apa":"He, S., Vickers, M., Zhang, J., &#38; Feng, X. (2019). Natural depletion of histone H1 in sex cells causes DNA demethylation, heterochromatin decondensation and transposon activation. <i>ELife</i>. eLife Sciences Publications, Ltd. <a href=\"https://doi.org/10.7554/elife.42530\">https://doi.org/10.7554/elife.42530</a>","ieee":"S. He, M. Vickers, J. Zhang, and X. Feng, “Natural depletion of histone H1 in sex cells causes DNA demethylation, heterochromatin decondensation and transposon activation,” <i>eLife</i>, vol. 8. eLife Sciences Publications, Ltd, 2019."},"main_file_link":[{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594752/","open_access":"1"}],"abstract":[{"text":"Transposable elements (TEs), the movement of which can damage the genome, are epigenetically silenced in eukaryotes. Intriguingly, TEs are activated in the sperm companion cell – vegetative cell (VC) – of the flowering plant Arabidopsis thaliana. However, the extent and mechanism of this activation are unknown. Here we show that about 100 heterochromatic TEs are activated in VCs, mostly by DEMETER-catalyzed DNA demethylation. We further demonstrate that DEMETER access to some of these TEs is permitted by the natural depletion of linker histone H1 in VCs. Ectopically expressed H1 suppresses TEs in VCs by reducing DNA demethylation and via a methylation-independent mechanism. We demonstrate that H1 is required for heterochromatin condensation in plant cells and show that H1 overexpression creates heterochromatic foci in the VC progenitor cell. Taken together, our results demonstrate that the natural depletion of H1 during male gametogenesis facilitates DEMETER-directed DNA demethylation, heterochromatin relaxation, and TE activation.","lang":"eng"}],"scopus_import":"1","acknowledgement":"We thank David Twell for the pDONR-P4-P1R-pLAT52 and pDONR-P2R-P3-mRFP vectors, the John Innes Centre Bioimaging Facility (Elaine Barclay and Grant Calder) for their assistance with microscopy, and the Norwich BioScience Institute Partnership Computing infrastructure for Science Group for High Performance Computing resources. This work was funded by a Biotechnology and Biological Sciences Research Council (BBSRC) David Phillips Fellowship (BB/L025043/1; SH, JZ and XF), a European Research Council Starting Grant ('SexMeth' 804981; XF) and a Grant to Exceptional Researchers by the Gatsby Charitable Foundation (SH and XF).","file":[{"file_id":"12525","relation":"main_file","success":1,"date_created":"2023-02-07T09:42:46Z","file_name":"2019_elife_He.pdf","date_updated":"2023-02-07T09:42:46Z","file_size":2493837,"creator":"alisjak","checksum":"ea6b89c20d59e5eb3646916fe5d568ad","content_type":"application/pdf","access_level":"open_access"}],"has_accepted_license":"1","day":"28","type":"journal_article","oa":1,"language":[{"iso":"eng"}],"quality_controlled":"1","title":"Natural depletion of histone H1 in sex cells causes DNA demethylation, heterochromatin decondensation and transposon activation","publication":"eLife","publisher":"eLife Sciences Publications, Ltd","doi":"10.7554/elife.42530","year":"2019","file_date_updated":"2023-02-07T09:42:46Z","date_published":"2019-05-28T00:00:00Z","intvolume":"         8","_id":"12192","ddc":["580"],"tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"status":"public","volume":8,"oa_version":"Published Version","date_updated":"2023-05-08T10:54:12Z","extern":"1"},{"article_type":"original","publication_identifier":{"issn":["0043-1397"],"eissn":["1944-7973"]},"author":[{"last_name":"Girona‐Mata","full_name":"Girona‐Mata, Marc","first_name":"Marc"},{"full_name":"Miles, Evan S.","last_name":"Miles","first_name":"Evan S."},{"first_name":"Silvan","full_name":"Ragettli, Silvan","last_name":"Ragettli"},{"last_name":"Pellicciotti","full_name":"Pellicciotti, Francesca","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70","first_name":"Francesca"}],"publication_status":"published","keyword":["Water Science and Technology"],"page":"6754-6772","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2023-02-20T08:12:59Z","issue":"8","abstract":[{"lang":"eng","text":"The snow cover dynamics of High Mountain Asia are usually assessed at spatial resolutions of 250 m or greater, but this scale is too coarse to clearly represent the rugged topography common to the region. Higher-resolution measurement of snow-covered area often results in biased sampling due to cloud cover and deep shadows. We therefore develop a Normalized Difference Snow Index-based workflow to delineate snow lines from Landsat Thematic Mapper/Enhanced Thematic Mapper+ imagery and apply it to the upper Langtang Valley in Nepal, processing 194 scenes spanning 1999 to 2013. For each scene, we determine the spatial distribution of snow line altitudes (SLAs) with respect to aspect and across six subcatchments. Our results show that the mean SLA exhibits distinct seasonal behavior based on aspect and subcatchment position. We find that SLA dynamics respond to spatial and seasonal trade-offs in precipitation, temperature, and solar radiation, which act as primary controls. We identify two SLA spatial gradients, which we attribute to the effect of spatially variable precipitation. Our results also reveal that aspect-related SLA differences vary seasonally and are influenced by solar radiation. In terms of seasonal dominant controls, we demonstrate that the snow line is controlled by snow precipitation in winter, melt in premonsoon, a combination of both in postmonsoon, and temperature in monsoon, explaining to a large extent the spatial and seasonal variability of the SLA in the upper Langtang Valley. We conclude that while SLA and snow-covered area are complementary metrics, the SLA has a strong potential for understanding local-scale snow cover dynamics and their controlling mechanisms."}],"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1029/2019WR024935"}],"scopus_import":"1","article_processing_charge":"No","month":"08","citation":{"short":"M. Girona‐Mata, E.S. Miles, S. Ragettli, F. Pellicciotti, Water Resources Research 55 (2019) 6754–6772.","mla":"Girona‐Mata, Marc, et al. “High‐resolution Snowline Delineation from Landsat Imagery to Infer Snow Cover Controls in a Himalayan Catchment.” <i>Water Resources Research</i>, vol. 55, no. 8, American Geophysical Union, 2019, pp. 6754–72, doi:<a href=\"https://doi.org/10.1029/2019wr024935\">10.1029/2019wr024935</a>.","ama":"Girona‐Mata M, Miles ES, Ragettli S, Pellicciotti F. High‐resolution snowline delineation from Landsat imagery to infer snow cover controls in a Himalayan catchment. <i>Water Resources Research</i>. 2019;55(8):6754-6772. doi:<a href=\"https://doi.org/10.1029/2019wr024935\">10.1029/2019wr024935</a>","ista":"Girona‐Mata M, Miles ES, Ragettli S, Pellicciotti F. 2019. High‐resolution snowline delineation from Landsat imagery to infer snow cover controls in a Himalayan catchment. Water Resources Research. 55(8), 6754–6772.","chicago":"Girona‐Mata, Marc, Evan S. Miles, Silvan Ragettli, and Francesca Pellicciotti. “High‐resolution Snowline Delineation from Landsat Imagery to Infer Snow Cover Controls in a Himalayan Catchment.” <i>Water Resources Research</i>. American Geophysical Union, 2019. <a href=\"https://doi.org/10.1029/2019wr024935\">https://doi.org/10.1029/2019wr024935</a>.","ieee":"M. Girona‐Mata, E. S. Miles, S. Ragettli, and F. Pellicciotti, “High‐resolution snowline delineation from Landsat imagery to infer snow cover controls in a Himalayan catchment,” <i>Water Resources Research</i>, vol. 55, no. 8. American Geophysical Union, pp. 6754–6772, 2019.","apa":"Girona‐Mata, M., Miles, E. S., Ragettli, S., &#38; Pellicciotti, F. (2019). High‐resolution snowline delineation from Landsat imagery to infer snow cover controls in a Himalayan catchment. <i>Water Resources Research</i>. American Geophysical Union. <a href=\"https://doi.org/10.1029/2019wr024935\">https://doi.org/10.1029/2019wr024935</a>"},"title":"High‐resolution snowline delineation from Landsat imagery to infer snow cover controls in a Himalayan catchment","doi":"10.1029/2019wr024935","publisher":"American Geophysical Union","publication":"Water Resources Research","language":[{"iso":"eng"}],"oa":1,"type":"journal_article","day":"01","quality_controlled":"1","date_updated":"2023-02-28T12:14:18Z","oa_version":"Published Version","volume":55,"extern":"1","date_published":"2019-08-01T00:00:00Z","year":"2019","status":"public","intvolume":"        55","_id":"12600"},{"article_processing_charge":"No","month":"08","citation":{"short":"J.F. STEINER, P. BURI, E.S. MILES, S. RAGETTLI, F. Pellicciotti, Journal of Glaciology 65 (2019) 617–632.","ista":"STEINER JF, BURI P, MILES ES, RAGETTLI S, Pellicciotti F. 2019. Supraglacial ice cliffs and ponds on debris-covered glaciers: Spatio-temporal distribution and characteristics. Journal of Glaciology. 65(252), 617–632.","mla":"STEINER, JAKOB F., et al. “Supraglacial Ice Cliffs and Ponds on Debris-Covered Glaciers: Spatio-Temporal Distribution and Characteristics.” <i>Journal of Glaciology</i>, vol. 65, no. 252, Cambridge University Press, 2019, pp. 617–32, doi:<a href=\"https://doi.org/10.1017/jog.2019.40\">10.1017/jog.2019.40</a>.","ama":"STEINER JF, BURI P, MILES ES, RAGETTLI S, Pellicciotti F. Supraglacial ice cliffs and ponds on debris-covered glaciers: Spatio-temporal distribution and characteristics. <i>Journal of Glaciology</i>. 2019;65(252):617-632. doi:<a href=\"https://doi.org/10.1017/jog.2019.40\">10.1017/jog.2019.40</a>","chicago":"STEINER, JAKOB F., PASCAL BURI, EVAN S. MILES, SILVAN RAGETTLI, and Francesca Pellicciotti. “Supraglacial Ice Cliffs and Ponds on Debris-Covered Glaciers: Spatio-Temporal Distribution and Characteristics.” <i>Journal of Glaciology</i>. Cambridge University Press, 2019. <a href=\"https://doi.org/10.1017/jog.2019.40\">https://doi.org/10.1017/jog.2019.40</a>.","apa":"STEINER, J. F., BURI, P., MILES, E. S., RAGETTLI, S., &#38; Pellicciotti, F. (2019). Supraglacial ice cliffs and ponds on debris-covered glaciers: Spatio-temporal distribution and characteristics. <i>Journal of Glaciology</i>. Cambridge University Press. <a href=\"https://doi.org/10.1017/jog.2019.40\">https://doi.org/10.1017/jog.2019.40</a>","ieee":"J. F. STEINER, P. BURI, E. S. MILES, S. RAGETTLI, and F. Pellicciotti, “Supraglacial ice cliffs and ponds on debris-covered glaciers: Spatio-temporal distribution and characteristics,” <i>Journal of Glaciology</i>, vol. 65, no. 252. Cambridge University Press, pp. 617–632, 2019."},"abstract":[{"text":"Ice cliffs and ponds on debris-covered glaciers have received increased attention due to their role in amplifying local melt. However, very few studies have looked at these features on the catchment scale to determine their patterns and changes in space and time. We have compiled a detailed inventory of cliffs and ponds in the Langtang catchment, central Himalaya, from six high-resolution satellite orthoimages and DEMs between 2006 and 2015, and a historic orthophoto from 1974. Cliffs cover between 1.4% (± 0.4%) in the dry and 3.4% (± 0.9%) in the wet seasons and ponds between 0.6% (± 0.1%) and 1.6% (± 0.3%) of the total debris-covered tongues. We find large variations between seasons, as cliffs and ponds tend to grow in the wetter monsoon period, but there is no obvious trend in total area over the study period. The inventory further shows that cliffs are predominately north-facing irrespective of the glacier flow direction. Both cliffs and ponds appear in higher densities several hundred metres from the terminus in areas where tributaries reach the main glacier tongue. On the largest glacier in the catchment ~10% of all cliffs and ponds persisted over nearly a decade.","lang":"eng"}],"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1017/jog.2019.40"}],"scopus_import":"1","page":"617-632","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2023-02-20T08:13:03Z","issue":"252","article_type":"original","publication_identifier":{"issn":["0022-1430"],"eissn":["1727-5652"]},"author":[{"full_name":"STEINER, JAKOB F.","last_name":"STEINER","first_name":"JAKOB F."},{"first_name":"PASCAL","full_name":"BURI, PASCAL","last_name":"BURI"},{"first_name":"EVAN S.","full_name":"MILES, EVAN S.","last_name":"MILES"},{"first_name":"SILVAN","full_name":"RAGETTLI, SILVAN","last_name":"RAGETTLI"},{"first_name":"Francesca","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70","full_name":"Pellicciotti, Francesca","last_name":"Pellicciotti"}],"publication_status":"published","date_published":"2019-08-01T00:00:00Z","year":"2019","status":"public","intvolume":"        65","_id":"12601","date_updated":"2023-02-28T12:11:07Z","volume":65,"oa_version":"Published Version","extern":"1","language":[{"iso":"eng"}],"type":"journal_article","oa":1,"day":"01","quality_controlled":"1","title":"Supraglacial ice cliffs and ponds on debris-covered glaciers: Spatio-temporal distribution and characteristics","publisher":"Cambridge University Press","doi":"10.1017/jog.2019.40","publication":"Journal of Glaciology"},{"publication_status":"published","author":[{"full_name":"Wijngaard, René R.","last_name":"Wijngaard","first_name":"René R."},{"last_name":"Steiner","full_name":"Steiner, Jakob F.","first_name":"Jakob F."},{"first_name":"Philip D. A.","last_name":"Kraaijenbrink","full_name":"Kraaijenbrink, Philip D. A."},{"last_name":"Klug","full_name":"Klug, Christoph","first_name":"Christoph"},{"full_name":"Adhikari, Surendra","last_name":"Adhikari","first_name":"Surendra"},{"first_name":"Argha","full_name":"Banerjee, Argha","last_name":"Banerjee"},{"last_name":"Pellicciotti","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70","full_name":"Pellicciotti, Francesca","first_name":"Francesca"},{"first_name":"Ludovicus P. H.","last_name":"van Beek","full_name":"van Beek, Ludovicus P. H."},{"first_name":"Marc F. P.","full_name":"Bierkens, Marc F. P.","last_name":"Bierkens"},{"first_name":"Arthur F.","last_name":"Lutz","full_name":"Lutz, Arthur F."},{"first_name":"Walter W.","last_name":"Immerzeel","full_name":"Immerzeel, Walter W."}],"publication_identifier":{"issn":["2296-6463"]},"article_type":"original","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2023-02-20T08:13:08Z","scopus_import":"1","abstract":[{"lang":"eng","text":"This study aims at developing and applying a spatially-distributed coupled glacier mass balance and ice-flow model to attribute the response of glaciers to natural and anthropogenic climate change. We focus on two glaciers with contrasting surface characteristics: a debris-covered glacier (Langtang Glacier in Nepal) and a clean-ice glacier (Hintereisferner in Austria). The model is applied from the end of the Little Ice Age (1850) to the present-day (2016) and is forced with four bias-corrected General Circulation Models (GCMs) from the historical experiment of the CMIP5 archive. The selected GCMs represent region-specific warm-dry, warm-wet, cold-dry, and cold-wet climate conditions. To isolate the effects of anthropogenic climate change on glacier mass balance and flow runs from these GCMs with and without further anthropogenic forcing after 1970 until 2016 are selected. The outcomes indicate that both glaciers experience the largest reduction in area and volume under warm climate conditions, whereas area and volume reductions are smaller under cold climate conditions. Simultaneously with changes in glacier area and volume, surface velocities generally decrease over time. Without further anthropogenic forcing the results reveal a 3% (9%) smaller decline in glacier area (volume) for the debris-covered glacier and a 18% (39%) smaller decline in glacier area (volume) for the clean-ice glacier. The difference in the magnitude between the two glaciers can mainly be attributed to differences in the response time of the glaciers, where the clean-ice glacier shows a much faster response to climate change. We conclude that the response of the two glaciers can mainly be attributed to anthropogenic climate change and that the impact is larger on the clean-ice glacier. The outcomes show that the model performs well under different climate conditions and that the developed approach can be used for regional-scale glacio-hydrological modeling."}],"main_file_link":[{"url":"https://doi.org/10.3389/feart.2019.00143","open_access":"1"}],"month":"06","citation":{"ieee":"R. R. Wijngaard <i>et al.</i>, “Modeling the response of the Langtang Glacier and the Hintereisferner to a changing climate since the Little Ice Age,” <i>Frontiers in Earth Science</i>, vol. 7. Frontiers Media, 2019.","apa":"Wijngaard, R. R., Steiner, J. F., Kraaijenbrink, P. D. A., Klug, C., Adhikari, S., Banerjee, A., … Immerzeel, W. W. (2019). Modeling the response of the Langtang Glacier and the Hintereisferner to a changing climate since the Little Ice Age. <i>Frontiers in Earth Science</i>. Frontiers Media. <a href=\"https://doi.org/10.3389/feart.2019.00143\">https://doi.org/10.3389/feart.2019.00143</a>","chicago":"Wijngaard, René R., Jakob F. Steiner, Philip D. A. Kraaijenbrink, Christoph Klug, Surendra Adhikari, Argha Banerjee, Francesca Pellicciotti, et al. “Modeling the Response of the Langtang Glacier and the Hintereisferner to a Changing Climate since the Little Ice Age.” <i>Frontiers in Earth Science</i>. Frontiers Media, 2019. <a href=\"https://doi.org/10.3389/feart.2019.00143\">https://doi.org/10.3389/feart.2019.00143</a>.","short":"R.R. Wijngaard, J.F. Steiner, P.D.A. Kraaijenbrink, C. Klug, S. Adhikari, A. Banerjee, F. Pellicciotti, L.P.H. van Beek, M.F.P. Bierkens, A.F. Lutz, W.W. Immerzeel, Frontiers in Earth Science 7 (2019).","ista":"Wijngaard RR, Steiner JF, Kraaijenbrink PDA, Klug C, Adhikari S, Banerjee A, Pellicciotti F, van Beek LPH, Bierkens MFP, Lutz AF, Immerzeel WW. 2019. Modeling the response of the Langtang Glacier and the Hintereisferner to a changing climate since the Little Ice Age. Frontiers in Earth Science. 7, 143.","ama":"Wijngaard RR, Steiner JF, Kraaijenbrink PDA, et al. Modeling the response of the Langtang Glacier and the Hintereisferner to a changing climate since the Little Ice Age. <i>Frontiers in Earth Science</i>. 2019;7. doi:<a href=\"https://doi.org/10.3389/feart.2019.00143\">10.3389/feart.2019.00143</a>","mla":"Wijngaard, René R., et al. “Modeling the Response of the Langtang Glacier and the Hintereisferner to a Changing Climate since the Little Ice Age.” <i>Frontiers in Earth Science</i>, vol. 7, 143, Frontiers Media, 2019, doi:<a href=\"https://doi.org/10.3389/feart.2019.00143\">10.3389/feart.2019.00143</a>."},"article_number":"143","article_processing_charge":"No","publication":"Frontiers in Earth Science","doi":"10.3389/feart.2019.00143","publisher":"Frontiers Media","title":"Modeling the response of the Langtang Glacier and the Hintereisferner to a changing climate since the Little Ice Age","quality_controlled":"1","type":"journal_article","oa":1,"day":"04","language":[{"iso":"eng"}],"extern":"1","volume":7,"oa_version":"Published Version","date_updated":"2023-02-28T12:04:48Z","_id":"12602","intvolume":"         7","status":"public","year":"2019","date_published":"2019-06-04T00:00:00Z"},{"file":[{"relation":"main_file","success":1,"date_created":"2023-05-16T07:27:09Z","file_id":"12970","file_name":"2019_AHPC_Schloegl.pdf","file_size":1097603,"creator":"dernst","date_updated":"2023-05-16T07:27:09Z","checksum":"acc8272027faaf30709c51ac5c58ffa4","access_level":"open_access","content_type":"application/pdf"}],"has_accepted_license":"1","main_file_link":[{"open_access":"1","url":"https://vsc.ac.at/fileadmin/user_upload/vsc/conferences/ahpc19/BOOKLET_AHPC19.pdf"}],"date_updated":"2023-05-16T07:29:32Z","oa_version":"Published Version","ddc":["000"],"department":[{"_id":"ScienComp"}],"citation":{"ista":"Schlögl A, Kiss J, Elefante S. 2019. Is Debian suitable for running an HPC Cluster? AHPC19 - Austrian HPC Meeting 2019 . AHPC: Austrian HPC Meeting, 25.","ama":"Schlögl A, Kiss J, Elefante S. Is Debian suitable for running an HPC Cluster? In: <i>AHPC19 - Austrian HPC Meeting 2019 </i>. Institut für Mathematik und wissenschaftliches Rechnen der Universität Graz; 2019:25.","short":"A. Schlögl, J. Kiss, S. Elefante, in:, AHPC19 - Austrian HPC Meeting 2019 , Institut für Mathematik und wissenschaftliches Rechnen der Universität Graz, 2019, p. 25.","mla":"Schlögl, Alois, et al. “Is Debian Suitable for Running an HPC Cluster?” <i>AHPC19 - Austrian HPC Meeting 2019 </i>, Institut für Mathematik und wissenschaftliches Rechnen der Universität Graz, 2019, p. 25.","chicago":"Schlögl, Alois, Janos Kiss, and Stefano Elefante. “Is Debian Suitable for Running an HPC Cluster?” In <i>AHPC19 - Austrian HPC Meeting 2019 </i>, 25. Institut für Mathematik und wissenschaftliches Rechnen der Universität Graz, 2019.","ieee":"A. Schlögl, J. Kiss, and S. Elefante, “Is Debian suitable for running an HPC Cluster?,” in <i>AHPC19 - Austrian HPC Meeting 2019 </i>, Grundlsee, Austria, 2019, p. 25.","apa":"Schlögl, A., Kiss, J., &#38; Elefante, S. (2019). Is Debian suitable for running an HPC Cluster? In <i>AHPC19 - Austrian HPC Meeting 2019 </i> (p. 25). Grundlsee, Austria: Institut für Mathematik und wissenschaftliches Rechnen der Universität Graz."},"status":"public","month":"02","_id":"12901","article_processing_charge":"No","date_published":"2019-02-27T00:00:00Z","year":"2019","file_date_updated":"2023-05-16T07:27:09Z","author":[{"orcid":"0000-0002-5621-8100","last_name":"Schlögl","id":"45BF87EE-F248-11E8-B48F-1D18A9856A87","full_name":"Schlögl, Alois","first_name":"Alois"},{"last_name":"Kiss","full_name":"Kiss, Janos","id":"3D3A06F8-F248-11E8-B48F-1D18A9856A87","first_name":"Janos"},{"full_name":"Elefante, Stefano","id":"490F40CE-F248-11E8-B48F-1D18A9856A87","last_name":"Elefante","first_name":"Stefano"}],"publisher":"Institut für Mathematik und wissenschaftliches Rechnen der Universität Graz","publication_status":"published","publication":"AHPC19 - Austrian HPC Meeting 2019 ","title":"Is Debian suitable for running an HPC Cluster?","date_created":"2023-05-05T12:48:48Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","conference":{"start_date":"2019-02-25","location":"Grundlsee, Austria","end_date":"2019-02-27","name":"AHPC: Austrian HPC Meeting"},"language":[{"iso":"eng"}],"page":"25","day":"27","type":"conference_abstract","oa":1},{"year":"2019","date_published":"2019-12-19T00:00:00Z","article_processing_charge":"No","_id":"9726","citation":{"short":"M.C. 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Supplementary information - Collective force generation by molecular motors is determined by strain-induced unbinding. American Chemical Society . <a href=\"https://doi.org/10.1021/acs.nanolett.9b04445.s001\">https://doi.org/10.1021/acs.nanolett.9b04445.s001</a>","ieee":"M. C. Ucar and R. 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Public Library of Science. <a href=\"https://doi.org/10.1371/journal.pgen.1008079.s011\">https://doi.org/10.1371/journal.pgen.1008079.s011</a>"},"month":"04","oa_version":"Published Version","date_updated":"2023-08-25T10:30:36Z","related_material":{"record":[{"status":"public","id":"6419","relation":"used_in_publication"}]}},{"related_material":{"record":[{"id":"6022","relation":"used_in_publication","status":"public"}]},"date_updated":"2023-08-24T14:46:23Z","oa_version":"Published Version","status":"public","month":"02","citation":{"short":"R.M. Merrill, P. Rastas, S.H. Martin, M.C. Melo Hurtado, S. Barker, J. Davey, W.O. Mcmillan, C.D. Jiggins, (2019).","mla":"Merrill, Richard M., et al. <i>Raw Behavioral Data</i>. Public Library of Science, 2019, doi:<a href=\"https://doi.org/10.1371/journal.pbio.2005902.s006\">10.1371/journal.pbio.2005902.s006</a>.","ista":"Merrill RM, Rastas P, Martin SH, Melo Hurtado MC, Barker S, Davey J, Mcmillan WO, Jiggins CD. 2019. Raw behavioral data, Public Library of Science, <a href=\"https://doi.org/10.1371/journal.pbio.2005902.s006\">10.1371/journal.pbio.2005902.s006</a>.","ama":"Merrill RM, Rastas P, Martin SH, et al. Raw behavioral data. 2019. doi:<a href=\"https://doi.org/10.1371/journal.pbio.2005902.s006\">10.1371/journal.pbio.2005902.s006</a>","ieee":"R. M. Merrill <i>et al.</i>, “Raw behavioral data.” Public Library of Science, 2019.","apa":"Merrill, R. M., Rastas, P., Martin, S. H., Melo Hurtado, M. C., Barker, S., Davey, J., … Jiggins, C. D. (2019). Raw behavioral data. Public Library of Science. <a href=\"https://doi.org/10.1371/journal.pbio.2005902.s006\">https://doi.org/10.1371/journal.pbio.2005902.s006</a>","chicago":"Merrill, Richard M., Pasi Rastas, Simon H. Martin, Maria C Melo Hurtado, Sarah Barker, John Davey, W. Owen Mcmillan, and Chris D. Jiggins. “Raw Behavioral Data.” Public Library of Science, 2019. <a href=\"https://doi.org/10.1371/journal.pbio.2005902.s006\">https://doi.org/10.1371/journal.pbio.2005902.s006</a>."},"department":[{"_id":"NiBa"}],"_id":"9801","date_published":"2019-02-07T00:00:00Z","article_processing_charge":"No","year":"2019","author":[{"first_name":"Richard M.","last_name":"Merrill","full_name":"Merrill, Richard M."},{"last_name":"Rastas","full_name":"Rastas, Pasi","first_name":"Pasi"},{"last_name":"Martin","full_name":"Martin, Simon H.","first_name":"Simon H."},{"first_name":"Maria C","id":"386D7308-F248-11E8-B48F-1D18A9856A87","full_name":"Melo Hurtado, Maria C","last_name":"Melo Hurtado"},{"first_name":"Sarah","last_name":"Barker","full_name":"Barker, Sarah"},{"last_name":"Davey","full_name":"Davey, John","first_name":"John"},{"first_name":"W. Owen","full_name":"Mcmillan, W. Owen","last_name":"Mcmillan"},{"first_name":"Chris D.","full_name":"Jiggins, Chris D.","last_name":"Jiggins"}],"doi":"10.1371/journal.pbio.2005902.s006","publisher":"Public Library of Science","title":"Raw behavioral data","user_id":"6785fbc1-c503-11eb-8a32-93094b40e1cf","date_created":"2021-08-06T11:34:56Z","type":"research_data_reference","day":"07"},{"title":"Data from: Effect of partial selfing and polygenic selection on establishment in a new habitat","publisher":"Dryad","doi":"10.5061/dryad.8tp0900","author":[{"first_name":"Himani","id":"42377A0A-F248-11E8-B48F-1D18A9856A87","full_name":"Sachdeva, Himani","last_name":"Sachdeva"}],"day":"16","type":"research_data_reference","oa":1,"date_created":"2021-08-06T11:45:11Z","user_id":"6785fbc1-c503-11eb-8a32-93094b40e1cf","oa_version":"Published Version","main_file_link":[{"open_access":"1","url":"https://doi.org/10.5061/dryad.8tp0900"}],"abstract":[{"lang":"eng","text":"This paper analyzes how partial selfing in a large source population influences its ability to colonize a new habitat via the introduction of a few founder individuals. Founders experience inbreeding depression due to partially recessive deleterious alleles as well as maladaptation to the new environment due to selection on a large number of additive loci. I first introduce a simplified version of the Inbreeding History Model (Kelly, 2007) in order to characterize mutation-selection balance in a large, partially selfing source population under selection involving multiple non-identical loci. I then use individual-based simulations to study the eco-evolutionary dynamics of founders establishing in the new habitat under a model of hard selection. The study explores how selfing rate shapes establishment probabilities of founders via effects on both inbreeding depression and adaptability to the new environment, and also distinguishes the effects of selfing on the initial fitness of founders from its effects on the long-term adaptive response of the populations they found. A high rate of (but not complete) selfing is found to aid establishment over a wide range of parameters, even in the absence of mate limitation. The sensitivity of the results to assumptions about the nature of polygenic selection are discussed."}],"date_updated":"2023-08-29T06:43:57Z","related_material":{"record":[{"status":"public","relation":"used_in_publication","id":"6680"}]},"year":"2019","article_processing_charge":"No","date_published":"2019-07-16T00:00:00Z","_id":"9802","department":[{"_id":"NiBa"}],"status":"public","month":"07","citation":{"short":"H. Sachdeva, (2019).","ama":"Sachdeva H. Data from: Effect of partial selfing and polygenic selection on establishment in a new habitat. 2019. doi:<a href=\"https://doi.org/10.5061/dryad.8tp0900\">10.5061/dryad.8tp0900</a>","ista":"Sachdeva H. 2019. 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