[{"publication":" Proceedings of the 13th International Conference of Reachability Problems","publisher":"Springer","department":[{"_id":"ToHe"}],"project":[{"call_identifier":"FWF","name":"Formal Methods meets Algorithmic Game Theory","_id":"264B3912-B435-11E9-9278-68D0E5697425","grant_number":"M02369"},{"grant_number":"S11402-N23","_id":"25F2ACDE-B435-11E9-9278-68D0E5697425","name":"Rigorous Systems Engineering","call_identifier":"FWF"},{"call_identifier":"FWF","grant_number":"Z211","name":"The Wittgenstein Prize","_id":"25F42A32-B435-11E9-9278-68D0E5697425"}],"day":"06","title":"Bidding games on Markov decision processes","citation":{"ista":"Avni G, Henzinger TA, Ibsen-Jensen R, Novotny P. 2019. Bidding games on Markov decision processes.  Proceedings of the 13th International Conference of Reachability Problems. RP: Reachability Problems, LNCS, vol. 11674, 1–12.","ama":"Avni G, Henzinger TA, Ibsen-Jensen R, Novotny P. Bidding games on Markov decision processes. In: <i> Proceedings of the 13th International Conference of Reachability Problems</i>. Vol 11674. Springer; 2019:1-12. doi:<a href=\"https://doi.org/10.1007/978-3-030-30806-3_1\">10.1007/978-3-030-30806-3_1</a>","ieee":"G. Avni, T. A. Henzinger, R. Ibsen-Jensen, and P. Novotny, “Bidding games on Markov decision processes,” in <i> Proceedings of the 13th International Conference of Reachability Problems</i>, Brussels, Belgium, 2019, vol. 11674, pp. 1–12.","chicago":"Avni, Guy, Thomas A Henzinger, Rasmus Ibsen-Jensen, and Petr Novotny. “Bidding Games on Markov Decision Processes.” In <i> Proceedings of the 13th International Conference of Reachability Problems</i>, 11674:1–12. Springer, 2019. <a href=\"https://doi.org/10.1007/978-3-030-30806-3_1\">https://doi.org/10.1007/978-3-030-30806-3_1</a>.","apa":"Avni, G., Henzinger, T. A., Ibsen-Jensen, R., &#38; Novotny, P. (2019). Bidding games on Markov decision processes. In <i> Proceedings of the 13th International Conference of Reachability Problems</i> (Vol. 11674, pp. 1–12). Brussels, Belgium: Springer. <a href=\"https://doi.org/10.1007/978-3-030-30806-3_1\">https://doi.org/10.1007/978-3-030-30806-3_1</a>","mla":"Avni, Guy, et al. “Bidding Games on Markov Decision Processes.” <i> Proceedings of the 13th International Conference of Reachability Problems</i>, vol. 11674, Springer, 2019, pp. 1–12, doi:<a href=\"https://doi.org/10.1007/978-3-030-30806-3_1\">10.1007/978-3-030-30806-3_1</a>.","short":"G. Avni, T.A. Henzinger, R. Ibsen-Jensen, P. Novotny, in:,  Proceedings of the 13th International Conference of Reachability Problems, Springer, 2019, pp. 1–12."},"doi":"10.1007/978-3-030-30806-3_1","abstract":[{"text":"In two-player games on graphs, the players move a token through a graph to produce an infinite path, which determines the qualitative winner or quantitative payoff of the game. In bidding games, in each turn, we hold an auction between the two players to determine which player moves the token. Bidding games have largely been studied with concrete bidding mechanisms that are variants of a first-price auction: in each turn both players simultaneously submit bids, the higher\r\nbidder moves the token, and pays his bid to the lower bidder in Richman bidding, to the bank in poorman bidding, and in taxman bidding, the bid is split between the other player and the bank according to a predefined constant factor. Bidding games are deterministic games. They have an intriguing connection with a fragment of stochastic games called \r\n randomturn games. We study, for the first time, a combination of bidding games with probabilistic behavior; namely, we study bidding games that are played on Markov decision processes, where the players bid for the right to choose the next action, which determines the probability distribution according to which the next vertex is chosen. We study parity and meanpayoff bidding games on MDPs and extend results from the deterministic bidding setting to the probabilistic one.","lang":"eng"}],"file":[{"file_size":436635,"file_id":"6823","date_updated":"2020-07-14T12:47:41Z","checksum":"45ebbc709af2b247d28c7c293c01504b","relation":"main_file","content_type":"application/pdf","access_level":"open_access","creator":"gavni","date_created":"2019-08-19T07:56:40Z","file_name":"prob.pdf"}],"page":"1-12","ddc":["000"],"oa":1,"year":"2019","date_updated":"2021-01-12T08:09:12Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","scopus_import":1,"date_published":"2019-09-06T00:00:00Z","has_accepted_license":"1","type":"conference","date_created":"2019-08-19T07:58:10Z","publication_identifier":{"isbn":["978-303030805-6"],"issn":["0302-9743"]},"volume":11674,"alternative_title":["LNCS"],"quality_controlled":"1","author":[{"orcid":"0000-0001-5588-8287","full_name":"Avni, Guy","first_name":"Guy","id":"463C8BC2-F248-11E8-B48F-1D18A9856A87","last_name":"Avni"},{"first_name":"Thomas A","full_name":"Henzinger, Thomas A","orcid":"0000−0002−2985−7724","last_name":"Henzinger","id":"40876CD8-F248-11E8-B48F-1D18A9856A87"},{"orcid":"0000-0003-4783-0389","full_name":"Ibsen-Jensen, Rasmus","first_name":"Rasmus","id":"3B699956-F248-11E8-B48F-1D18A9856A87","last_name":"Ibsen-Jensen"},{"last_name":"Novotny","full_name":"Novotny, Petr","first_name":"Petr"}],"conference":{"name":"RP: Reachability Problems","start_date":"2019-09-11","end_date":"2019-09-13","location":"Brussels, Belgium"},"status":"public","file_date_updated":"2020-07-14T12:47:41Z","_id":"6822","oa_version":"Submitted Version","publication_status":"published","month":"09","intvolume":"     11674","language":[{"iso":"eng"}]},{"quality_controlled":"1","author":[{"orcid":"0000-0001-6120-3723","full_name":"Gärtner, Florian R","first_name":"Florian R","id":"397A88EE-F248-11E8-B48F-1D18A9856A87","last_name":"Gärtner"},{"first_name":"Steffen","full_name":"Massberg, Steffen","last_name":"Massberg"}],"article_processing_charge":"No","status":"public","_id":"6824","oa_version":"None","intvolume":"        19","external_id":{"pmid":["31409920"],"isi":["000499090600011"]},"month":"12","publication_status":"published","language":[{"iso":"eng"}],"article_type":"original","year":"2019","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","date_updated":"2023-08-29T07:16:14Z","scopus_import":"1","ec_funded":1,"type":"journal_article","date_created":"2019-08-20T17:24:32Z","publication_identifier":{"issn":["1474-1733"],"eissn":["1474-1741"]},"volume":19,"date_published":"2019-12-01T00:00:00Z","pmid":1,"page":"747–760","abstract":[{"lang":"eng","text":"Platelets are small anucleate cellular fragments that are released by megakaryocytes and safeguard vascular integrity through a process termed ‘haemostasis’. However, platelets have important roles beyond haemostasis as they contribute to the initiation and coordination of intravascular immune responses. They continuously monitor blood vessel integrity and tightly coordinate vascular trafficking and functions of multiple cell types. In this way platelets act as ‘patrolling officers of the vascular highway’ that help to establish effective immune responses to infections and cancer. Here we discuss the distinct biological features of platelets that allow them to shape immune responses to pathogens and tumour cells, highlighting the parallels between these responses."}],"issue":"12","title":"Patrolling the vascular borders: Platelets in immunity to infection and cancer","citation":{"ieee":"F. R. Gärtner and S. Massberg, “Patrolling the vascular borders: Platelets in immunity to infection and cancer,” <i>Nature Reviews Immunology</i>, vol. 19, no. 12. Springer Nature, pp. 747–760, 2019.","ama":"Gärtner FR, Massberg S. Patrolling the vascular borders: Platelets in immunity to infection and cancer. <i>Nature Reviews Immunology</i>. 2019;19(12):747–760. doi:<a href=\"https://doi.org/10.1038/s41577-019-0202-z\">10.1038/s41577-019-0202-z</a>","ista":"Gärtner FR, Massberg S. 2019. Patrolling the vascular borders: Platelets in immunity to infection and cancer. Nature Reviews Immunology. 19(12), 747–760.","apa":"Gärtner, F. R., &#38; Massberg, S. (2019). Patrolling the vascular borders: Platelets in immunity to infection and cancer. <i>Nature Reviews Immunology</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41577-019-0202-z\">https://doi.org/10.1038/s41577-019-0202-z</a>","short":"F.R. Gärtner, S. Massberg, Nature Reviews Immunology 19 (2019) 747–760.","mla":"Gärtner, Florian R., and Steffen Massberg. “Patrolling the Vascular Borders: Platelets in Immunity to Infection and Cancer.” <i>Nature Reviews Immunology</i>, vol. 19, no. 12, Springer Nature, 2019, pp. 747–760, doi:<a href=\"https://doi.org/10.1038/s41577-019-0202-z\">10.1038/s41577-019-0202-z</a>.","chicago":"Gärtner, Florian R, and Steffen Massberg. “Patrolling the Vascular Borders: Platelets in Immunity to Infection and Cancer.” <i>Nature Reviews Immunology</i>. Springer Nature, 2019. <a href=\"https://doi.org/10.1038/s41577-019-0202-z\">https://doi.org/10.1038/s41577-019-0202-z</a>."},"publication":"Nature Reviews Immunology","publisher":"Springer Nature","department":[{"_id":"MiSi"}],"project":[{"grant_number":"747687","name":"Mechanical Adaptation of Lamellipodial Actin Networks in Migrating Cells","_id":"260AA4E2-B435-11E9-9278-68D0E5697425","call_identifier":"H2020"}],"day":"01","isi":1,"doi":"10.1038/s41577-019-0202-z"},{"day":"24","department":[{"_id":"JoCs"}],"publisher":"Institute of Science and Technology Austria","citation":{"chicago":"Käfer, Karola. “The Hippocampus and Medial Prefrontal Cortex during Flexible Behavior.” Institute of Science and Technology Austria, 2019. <a href=\"https://doi.org/10.15479/AT:ISTA:6825\">https://doi.org/10.15479/AT:ISTA:6825</a>.","mla":"Käfer, Karola. <i>The Hippocampus and Medial Prefrontal Cortex during Flexible Behavior</i>. Institute of Science and Technology Austria, 2019, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:6825\">10.15479/AT:ISTA:6825</a>.","short":"K. Käfer, The Hippocampus and Medial Prefrontal Cortex during Flexible Behavior, Institute of Science and Technology Austria, 2019.","apa":"Käfer, K. (2019). <i>The hippocampus and medial prefrontal cortex during flexible behavior</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:6825\">https://doi.org/10.15479/AT:ISTA:6825</a>","ista":"Käfer K. 2019. The hippocampus and medial prefrontal cortex during flexible behavior. Institute of Science and Technology Austria.","ieee":"K. Käfer, “The hippocampus and medial prefrontal cortex during flexible behavior,” Institute of Science and Technology Austria, 2019.","ama":"Käfer K. The hippocampus and medial prefrontal cortex during flexible behavior. 2019. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:6825\">10.15479/AT:ISTA:6825</a>"},"title":"The hippocampus and medial prefrontal cortex during flexible behavior","related_material":{"record":[{"id":"5949","status":"public","relation":"part_of_dissertation"}]},"doi":"10.15479/AT:ISTA:6825","abstract":[{"lang":"eng","text":"The solving of complex tasks requires the functions of more than one brain area and their interaction. Whilst spatial navigation and memory is dependent on the hippocampus, flexible behavior relies on the medial prefrontal cortex (mPFC). To further examine the roles of the hippocampus and mPFC, we recorded their neural activity during a task that depends on both of these brain regions.\r\nWith tetrodes, we recorded the extracellular activity of dorsal hippocampal CA1 (HPC) and mPFC neurons in Long-Evans rats performing a rule-switching task on the plus-maze. The plus-maze task had a spatial component since it required navigation along one of the two start arms and at the maze center a choice between one of the two goal arms. Which goal contained a reward depended on the rule currently in place. After an uncued rule change the animal had to abandon the old strategy and switch to the new rule, testing cognitive flexibility. Investigating the coordination of activity between the HPC and mPFC allows determination during which task stages their interaction is required. Additionally, comparing neural activity patterns in these two brain regions allows delineation of the specialized functions of the HPC and mPFC in this task. We analyzed neural activity in the HPC and mPFC in terms of oscillatory interactions, rule coding and replay.\r\nWe found that theta coherence between the HPC and mPFC is increased at the center and goals of the maze, both when the rule was stable or has changed. Similar results were found for locking of HPC and mPFC neurons to HPC theta oscillations. However, no differences in HPC-mPFC theta coordination were observed between the spatially- and cue-guided rule. Phase locking of HPC and mPFC neurons to HPC gamma oscillations was not modulated by\r\nmaze position or rule type. We found that the HPC coded for the two different rules with cofiring relationships between\r\ncell pairs. However, we could not find conclusive evidence for rule coding in the mPFC. Spatially-selective firing in the mPFC generalized between the two start and two goal arms. With Bayesian positional decoding, we found that the mPFC reactivated non-local positions during awake immobility periods. Replay of these non-local positions could represent entire behavioral trajectories resembling trajectory replay of the HPC. Furthermore, mPFC\r\ntrajectory-replay at the goal positively correlated with rule-switching performance. \r\nFinally, HPC and mPFC trajectory replay occurred independently of each other. These results show that the mPFC can replay ordered patterns of activity during awake immobility, possibly underlying its role in flexible behavior. "}],"page":"89","file":[{"file_name":"Thesis_Kaefer_PDFA.pdf","date_created":"2019-09-03T08:07:13Z","embargo":"2020-09-05","content_type":"application/pdf","creator":"kkaefer","access_level":"open_access","relation":"main_file","checksum":"2664420e332a33338568f4f3bfc59287","date_updated":"2020-09-06T22:30:03Z","request_a_copy":0,"file_id":"6846","file_size":3205202},{"checksum":"9a154eab6f07aa590a3d2651dc0d926a","relation":"main_file","creator":"kkaefer","access_level":"closed","content_type":"application/zip","file_size":2506835,"file_id":"6847","date_updated":"2020-09-15T22:30:05Z","embargo_to":"open_access","file_name":"Thesis_Kaefer.zip","date_created":"2019-09-03T08:07:17Z"}],"degree_awarded":"PhD","ddc":["570"],"oa":1,"supervisor":[{"first_name":"Jozsef L","full_name":"Csicsvari, Jozsef L","orcid":"0000-0002-5193-4036","last_name":"Csicsvari","id":"3FA14672-F248-11E8-B48F-1D18A9856A87"}],"date_updated":"2023-09-07T13:01:42Z","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","year":"2019","has_accepted_license":"1","date_published":"2019-08-24T00:00:00Z","publication_identifier":{"issn":["2663-337X"]},"date_created":"2019-08-21T15:00:57Z","type":"dissertation","alternative_title":["ISTA Thesis"],"article_processing_charge":"No","author":[{"id":"2DAA49AA-F248-11E8-B48F-1D18A9856A87","last_name":"Käfer","full_name":"Käfer, Karola","first_name":"Karola"}],"language":[{"iso":"eng"}],"publication_status":"published","month":"08","oa_version":"Published Version","_id":"6825","status":"public","file_date_updated":"2020-09-15T22:30:05Z"},{"article_type":"original","language":[{"iso":"eng"}],"publication_status":"published","month":"11","external_id":{"arxiv":["1805.04676"],"isi":["000487176300011"]},"intvolume":"       538","_id":"6828","oa_version":"Preprint","status":"public","article_processing_charge":"No","author":[{"first_name":"Adam","full_name":"Brown, Adam","last_name":"Brown","id":"70B7FDF6-608D-11E9-9333-8535E6697425"}],"quality_controlled":"1","date_published":"2019-11-15T00:00:00Z","volume":538,"publication_identifier":{"issn":["0021-8693"]},"date_created":"2019-08-22T07:54:13Z","type":"journal_article","oa":1,"arxiv":1,"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","date_updated":"2023-08-29T07:11:47Z","year":"2019","abstract":[{"text":"In this paper we construct a family of exact functors from the category of Whittaker modules of the simple complex Lie algebra of type  to the category of finite-dimensional modules of the graded affine Hecke algebra of type . Using results of Backelin [2] and of Arakawa-Suzuki [1], we prove that these functors map standard modules to standard modules (or zero) and simple modules to simple modules (or zero). Moreover, we show that each simple module of the graded affine Hecke algebra appears as the image of a simple Whittaker module. Since the Whittaker category contains the BGG category  as a full subcategory, our results generalize results of Arakawa-Suzuki [1], which in turn generalize Schur-Weyl duality between finite-dimensional representations of  and representations of the symmetric group .","lang":"eng"}],"page":"261-289","doi":"10.1016/j.jalgebra.2019.07.027","isi":1,"day":"15","main_file_link":[{"url":"https://arxiv.org/abs/1805.04676","open_access":"1"}],"department":[{"_id":"HeEd"}],"publication":"Journal of Algebra","publisher":"Elsevier","citation":{"chicago":"Brown, Adam. “Arakawa-Suzuki Functors for Whittaker Modules.” <i>Journal of Algebra</i>. Elsevier, 2019. <a href=\"https://doi.org/10.1016/j.jalgebra.2019.07.027\">https://doi.org/10.1016/j.jalgebra.2019.07.027</a>.","apa":"Brown, A. (2019). Arakawa-Suzuki functors for Whittaker modules. <i>Journal of Algebra</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.jalgebra.2019.07.027\">https://doi.org/10.1016/j.jalgebra.2019.07.027</a>","short":"A. Brown, Journal of Algebra 538 (2019) 261–289.","mla":"Brown, Adam. “Arakawa-Suzuki Functors for Whittaker Modules.” <i>Journal of Algebra</i>, vol. 538, Elsevier, 2019, pp. 261–89, doi:<a href=\"https://doi.org/10.1016/j.jalgebra.2019.07.027\">10.1016/j.jalgebra.2019.07.027</a>.","ista":"Brown A. 2019. Arakawa-Suzuki functors for Whittaker modules. Journal of Algebra. 538, 261–289.","ama":"Brown A. Arakawa-Suzuki functors for Whittaker modules. <i>Journal of Algebra</i>. 2019;538:261-289. doi:<a href=\"https://doi.org/10.1016/j.jalgebra.2019.07.027\">10.1016/j.jalgebra.2019.07.027</a>","ieee":"A. Brown, “Arakawa-Suzuki functors for Whittaker modules,” <i>Journal of Algebra</i>, vol. 538. Elsevier, pp. 261–289, 2019."},"title":"Arakawa-Suzuki functors for Whittaker modules"},{"issue":"5","page":"750-752","pmid":1,"isi":1,"doi":"10.1016/j.neuron.2019.08.021","citation":{"ieee":"X. Contreras and S. Hippenmeyer, “Memo1 tiles the radial glial cell grid,” <i>Neuron</i>, vol. 103, no. 5. Elsevier, pp. 750–752, 2019.","ama":"Contreras X, Hippenmeyer S. Memo1 tiles the radial glial cell grid. <i>Neuron</i>. 2019;103(5):750-752. doi:<a href=\"https://doi.org/10.1016/j.neuron.2019.08.021\">10.1016/j.neuron.2019.08.021</a>","ista":"Contreras X, Hippenmeyer S. 2019. Memo1 tiles the radial glial cell grid. Neuron. 103(5), 750–752.","apa":"Contreras, X., &#38; Hippenmeyer, S. (2019). Memo1 tiles the radial glial cell grid. <i>Neuron</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.neuron.2019.08.021\">https://doi.org/10.1016/j.neuron.2019.08.021</a>","mla":"Contreras, Ximena, and Simon Hippenmeyer. “Memo1 Tiles the Radial Glial Cell Grid.” <i>Neuron</i>, vol. 103, no. 5, Elsevier, 2019, pp. 750–52, doi:<a href=\"https://doi.org/10.1016/j.neuron.2019.08.021\">10.1016/j.neuron.2019.08.021</a>.","short":"X. Contreras, S. Hippenmeyer, Neuron 103 (2019) 750–752.","chicago":"Contreras, Ximena, and Simon Hippenmeyer. “Memo1 Tiles the Radial Glial Cell Grid.” <i>Neuron</i>. Elsevier, 2019. <a href=\"https://doi.org/10.1016/j.neuron.2019.08.021\">https://doi.org/10.1016/j.neuron.2019.08.021</a>."},"title":"Memo1 tiles the radial glial cell grid","related_material":{"record":[{"id":"7902","status":"public","relation":"part_of_dissertation"}]},"day":"04","publisher":"Elsevier","publication":"Neuron","department":[{"_id":"SiHi"}],"main_file_link":[{"url":"https://doi.org/10.1016/j.neuron.2019.08.021","open_access":"1"}],"month":"09","intvolume":"       103","publication_status":"published","external_id":{"pmid":["31487522"],"isi":["000484400200002"]},"language":[{"iso":"eng"}],"status":"public","oa_version":"Published Version","_id":"6830","article_type":"letter_note","author":[{"id":"475990FE-F248-11E8-B48F-1D18A9856A87","last_name":"Contreras","full_name":"Contreras, Ximena","first_name":"Ximena"},{"last_name":"Hippenmeyer","id":"37B36620-F248-11E8-B48F-1D18A9856A87","first_name":"Simon","full_name":"Hippenmeyer, Simon","orcid":"0000-0003-2279-1061"}],"quality_controlled":"1","article_processing_charge":"No","publication_identifier":{"issn":["08966273"],"eissn":["10974199"]},"volume":103,"type":"journal_article","date_created":"2019-08-25T22:00:50Z","date_published":"2019-09-04T00:00:00Z","date_updated":"2024-03-25T23:30:23Z","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","scopus_import":"1","year":"2019","oa":1},{"citation":{"ama":"Puixeu Sala G, Pickup M, Field D, Barrett SCH. Variation in sexual dimorphism in a wind-pollinated plant: The influence of geographical context and life-cycle dynamics. <i>New Phytologist</i>. 2019;224(3):1108-1120. doi:<a href=\"https://doi.org/10.1111/nph.16050\">10.1111/nph.16050</a>","ieee":"G. Puixeu Sala, M. Pickup, D. Field, and S. C. H. Barrett, “Variation in sexual dimorphism in a wind-pollinated plant: The influence of geographical context and life-cycle dynamics,” <i>New Phytologist</i>, vol. 224, no. 3. Wiley, pp. 1108–1120, 2019.","ista":"Puixeu Sala G, Pickup M, Field D, Barrett SCH. 2019. Variation in sexual dimorphism in a wind-pollinated plant: The influence of geographical context and life-cycle dynamics. New Phytologist. 224(3), 1108–1120.","mla":"Puixeu Sala, Gemma, et al. “Variation in Sexual Dimorphism in a Wind-Pollinated Plant: The Influence of Geographical Context and Life-Cycle Dynamics.” <i>New Phytologist</i>, vol. 224, no. 3, Wiley, 2019, pp. 1108–20, doi:<a href=\"https://doi.org/10.1111/nph.16050\">10.1111/nph.16050</a>.","short":"G. Puixeu Sala, M. Pickup, D. Field, S.C.H. Barrett, New Phytologist 224 (2019) 1108–1120.","apa":"Puixeu Sala, G., Pickup, M., Field, D., &#38; Barrett, S. C. H. (2019). Variation in sexual dimorphism in a wind-pollinated plant: The influence of geographical context and life-cycle dynamics. <i>New Phytologist</i>. Wiley. <a href=\"https://doi.org/10.1111/nph.16050\">https://doi.org/10.1111/nph.16050</a>","chicago":"Puixeu Sala, Gemma, Melinda Pickup, David Field, and Spencer C.H. Barrett. “Variation in Sexual Dimorphism in a Wind-Pollinated Plant: The Influence of Geographical Context and Life-Cycle Dynamics.” <i>New Phytologist</i>. Wiley, 2019. <a href=\"https://doi.org/10.1111/nph.16050\">https://doi.org/10.1111/nph.16050</a>."},"title":"Variation in sexual dimorphism in a wind-pollinated plant: The influence of geographical context and life-cycle dynamics","related_material":{"record":[{"id":"9803","status":"public","relation":"research_data"},{"id":"14058","status":"public","relation":"dissertation_contains"}]},"project":[{"grant_number":"665385","_id":"2564DBCA-B435-11E9-9278-68D0E5697425","name":"International IST Doctoral Program","call_identifier":"H2020"}],"day":"01","publication":"New Phytologist","publisher":"Wiley","department":[{"_id":"NiBa"},{"_id":"BeVi"}],"isi":1,"doi":"10.1111/nph.16050","page":"1108-1120","file":[{"file_size":2314016,"file_id":"6833","date_updated":"2020-07-14T12:47:42Z","checksum":"6370e7567d96b7b562e77d8b89653f80","relation":"main_file","creator":"apreinsp","content_type":"application/pdf","access_level":"open_access","date_created":"2019-08-27T12:44:54Z","file_name":"2019_NewPhytologist_Puixeu.pdf"}],"abstract":[{"text":"* Understanding the mechanisms causing phenotypic differences between females and males has long fascinated evolutionary biologists. An extensive literature exists on animal sexual dimorphism but less information is known about sex differences in plants, particularly the extent of geographical variation in sexual dimorphism and its life‐cycle dynamics.\r\n* Here, we investigated patterns of genetically based sexual dimorphism in vegetative and reproductive traits of a wind‐pollinated dioecious plant, Rumex hastatulus, across three life‐cycle stages using open‐pollinated families from 30 populations spanning the geographic range and chromosomal variation (XY and XY1Y2) of the species.\r\n* The direction and degree of sexual dimorphism was highly variable among populations and life‐cycle stages. Sex‐specific differences in reproductive function explained a significant amount of temporal change in sexual dimorphism. For several traits, geographical variation in sexual dimorphism was associated with bioclimatic parameters, likely due to the differential responses of the sexes to climate. We found no systematic differences in sexual dimorphism between chromosome races.\r\n* Sex‐specific trait differences in dioecious plants largely result from a balance between sexual and natural selection on resource allocation. Our results indicate that abiotic factors associated with geographical context also play a role in modifying sexual dimorphism during the plant life‐cycle.","lang":"eng"}],"ddc":["570"],"issue":"3","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","date_updated":"2023-08-29T07:17:07Z","scopus_import":"1","year":"2019","oa":1,"ec_funded":1,"publication_identifier":{"eissn":["1469-8137"]},"volume":224,"type":"journal_article","tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"date_created":"2019-08-25T22:00:51Z","has_accepted_license":"1","date_published":"2019-11-01T00:00:00Z","author":[{"id":"33AB266C-F248-11E8-B48F-1D18A9856A87","last_name":"Puixeu Sala","full_name":"Puixeu Sala, Gemma","orcid":"0000-0001-8330-1754","first_name":"Gemma"},{"full_name":"Pickup, Melinda","orcid":"0000-0001-6118-0541","first_name":"Melinda","id":"2C78037E-F248-11E8-B48F-1D18A9856A87","last_name":"Pickup"},{"last_name":"Field","orcid":"0000-0002-4014-8478","full_name":"Field, David","first_name":"David"},{"last_name":"Barrett","full_name":"Barrett, Spencer C.H.","first_name":"Spencer C.H."}],"quality_controlled":"1","article_processing_charge":"Yes (via OA deal)","external_id":{"isi":["000481376500001"]},"intvolume":"       224","publication_status":"published","month":"11","language":[{"iso":"eng"}],"file_date_updated":"2020-07-14T12:47:42Z","status":"public","_id":"6831","oa_version":"Published Version","article_type":"original"},{"year":"2019","scopus_import":"1","date_updated":"2023-08-29T07:16:40Z","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","date_published":"2019-08-16T00:00:00Z","date_created":"2019-08-25T22:00:51Z","type":"journal_article","volume":365,"article_processing_charge":"No","quality_controlled":"1","author":[{"last_name":"Krndija","full_name":"Krndija, Denis","first_name":"Denis"},{"first_name":"Fatima El","full_name":"Marjou, Fatima El","last_name":"Marjou"},{"last_name":"Guirao","first_name":"Boris","full_name":"Guirao, Boris"},{"first_name":"Sophie","full_name":"Richon, Sophie","last_name":"Richon"},{"full_name":"Leroy, Olivier","first_name":"Olivier","last_name":"Leroy"},{"first_name":"Yohanns","full_name":"Bellaiche, Yohanns","last_name":"Bellaiche"},{"last_name":"Hannezo","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","first_name":"Edouard B","orcid":"0000-0001-6005-1561","full_name":"Hannezo, Edouard B"},{"last_name":"Vignjevic","first_name":"Danijela Matic","full_name":"Vignjevic, Danijela Matic"}],"oa_version":"None","_id":"6832","status":"public","language":[{"iso":"eng"}],"month":"08","intvolume":"       365","publication_status":"published","external_id":{"isi":["000481688700050"],"pmid":["31416964"]},"department":[{"_id":"EdHa"}],"publisher":"American Association for the Advancement of Science","publication":"Science","day":"16","title":"Active cell migration is critical for steady-state epithelial turnover in the gut","citation":{"chicago":"Krndija, Denis, Fatima El Marjou, Boris Guirao, Sophie Richon, Olivier Leroy, Yohanns Bellaiche, Edouard B Hannezo, and Danijela Matic Vignjevic. “Active Cell Migration Is Critical for Steady-State Epithelial Turnover in the Gut.” <i>Science</i>. American Association for the Advancement of Science, 2019. <a href=\"https://doi.org/10.1126/science.aau3429\">https://doi.org/10.1126/science.aau3429</a>.","apa":"Krndija, D., Marjou, F. E., Guirao, B., Richon, S., Leroy, O., Bellaiche, Y., … Vignjevic, D. M. (2019). Active cell migration is critical for steady-state epithelial turnover in the gut. <i>Science</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/science.aau3429\">https://doi.org/10.1126/science.aau3429</a>","mla":"Krndija, Denis, et al. “Active Cell Migration Is Critical for Steady-State Epithelial Turnover in the Gut.” <i>Science</i>, vol. 365, no. 6454, American Association for the Advancement of Science, 2019, pp. 705–10, doi:<a href=\"https://doi.org/10.1126/science.aau3429\">10.1126/science.aau3429</a>.","short":"D. Krndija, F.E. Marjou, B. Guirao, S. Richon, O. Leroy, Y. Bellaiche, E.B. Hannezo, D.M. Vignjevic, Science 365 (2019) 705–710.","ista":"Krndija D, Marjou FE, Guirao B, Richon S, Leroy O, Bellaiche Y, Hannezo EB, Vignjevic DM. 2019. Active cell migration is critical for steady-state epithelial turnover in the gut. Science. 365(6454), 705–710.","ama":"Krndija D, Marjou FE, Guirao B, et al. Active cell migration is critical for steady-state epithelial turnover in the gut. <i>Science</i>. 2019;365(6454):705-710. doi:<a href=\"https://doi.org/10.1126/science.aau3429\">10.1126/science.aau3429</a>","ieee":"D. Krndija <i>et al.</i>, “Active cell migration is critical for steady-state epithelial turnover in the gut,” <i>Science</i>, vol. 365, no. 6454. American Association for the Advancement of Science, pp. 705–710, 2019."},"doi":"10.1126/science.aau3429","isi":1,"abstract":[{"lang":"eng","text":"Steady-state turnover is a hallmark of epithelial tissues throughout adult life. Intestinal epithelial turnover is marked by continuous cell migration, which is assumed to be driven by mitotic pressure from the crypts. However, the balance of forces in renewal remains ill-defined. Combining biophysical modeling and quantitative three-dimensional tissue imaging with genetic and physical manipulations, we revealed the existence of an actin-related protein 2/3 complex–dependent active migratory force, which explains quantitatively the profiles of cell speed, density, and tissue tension along the villi. Cells migrate collectively with minimal rearrangements while displaying dual—apicobasal and front-back—polarity characterized by actin-rich basal protrusions oriented in the direction of migration. We propose that active migration is a critical component of gut epithelial turnover."}],"pmid":1,"page":"705-710","issue":"6454"},{"day":"01","publisher":"Elsevier","publication":"Bulletin des Sciences Mathematiques","department":[{"_id":"TiBr"}],"main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1801.03082"}],"citation":{"apa":"Destagnol, K. N., &#38; Sofos, E. (2019). Rational points and prime values of polynomials in moderately many variables. <i>Bulletin Des Sciences Mathematiques</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.bulsci.2019.102794\">https://doi.org/10.1016/j.bulsci.2019.102794</a>","mla":"Destagnol, Kevin N., and Efthymios Sofos. “Rational Points and Prime Values of Polynomials in Moderately Many Variables.” <i>Bulletin Des Sciences Mathematiques</i>, vol. 156, no. 11, 102794, Elsevier, 2019, doi:<a href=\"https://doi.org/10.1016/j.bulsci.2019.102794\">10.1016/j.bulsci.2019.102794</a>.","short":"K.N. Destagnol, E. Sofos, Bulletin Des Sciences Mathematiques 156 (2019).","chicago":"Destagnol, Kevin N, and Efthymios Sofos. “Rational Points and Prime Values of Polynomials in Moderately Many Variables.” <i>Bulletin Des Sciences Mathematiques</i>. Elsevier, 2019. <a href=\"https://doi.org/10.1016/j.bulsci.2019.102794\">https://doi.org/10.1016/j.bulsci.2019.102794</a>.","ama":"Destagnol KN, Sofos E. Rational points and prime values of polynomials in moderately many variables. <i>Bulletin des Sciences Mathematiques</i>. 2019;156(11). doi:<a href=\"https://doi.org/10.1016/j.bulsci.2019.102794\">10.1016/j.bulsci.2019.102794</a>","ieee":"K. N. Destagnol and E. Sofos, “Rational points and prime values of polynomials in moderately many variables,” <i>Bulletin des Sciences Mathematiques</i>, vol. 156, no. 11. Elsevier, 2019.","ista":"Destagnol KN, Sofos E. 2019. Rational points and prime values of polynomials in moderately many variables. Bulletin des Sciences Mathematiques. 156(11), 102794."},"title":"Rational points and prime values of polynomials in moderately many variables","isi":1,"doi":"10.1016/j.bulsci.2019.102794","abstract":[{"lang":"eng","text":"We derive the Hasse principle and weak approximation for fibrations of certain varieties in the spirit of work by Colliot-Thélène–Sansuc and Harpaz–Skorobogatov–Wittenberg. Our varieties are defined through polynomials in many variables and part of our work is devoted to establishing Schinzel's hypothesis for polynomials of this kind. This last part is achieved by using arguments behind Birch's well-known result regarding the Hasse principle for complete intersections with the notable difference that we prove our result in 50% fewer variables than in the classical Birch setting. We also study the problem of square-free values of an integer polynomial with 66.6% fewer variables than in the Birch setting."}],"issue":"11","article_number":"102794","oa":1,"arxiv":1,"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","date_updated":"2023-08-29T07:18:02Z","scopus_import":"1","year":"2019","date_published":"2019-11-01T00:00:00Z","publication_identifier":{"issn":["0007-4497"]},"volume":156,"type":"journal_article","date_created":"2019-09-01T22:00:55Z","article_processing_charge":"No","author":[{"last_name":"Destagnol","id":"44DDECBC-F248-11E8-B48F-1D18A9856A87","first_name":"Kevin N","full_name":"Destagnol, Kevin N"},{"full_name":"Sofos, Efthymios","first_name":"Efthymios","last_name":"Sofos"}],"quality_controlled":"1","article_type":"original","month":"11","publication_status":"published","external_id":{"isi":["000496342100002"],"arxiv":["1801.03082"]},"intvolume":"       156","language":[{"iso":"eng"}],"status":"public","oa_version":"Preprint","_id":"6835"},{"issue":"7770","ddc":["000"],"abstract":[{"text":"Direct reciprocity is a powerful mechanism for the evolution of cooperation on the basis of repeated interactions1,2,3,4. It requires that interacting individuals are sufficiently equal, such that everyone faces similar consequences when they cooperate or defect. Yet inequality is ubiquitous among humans5,6 and is generally considered to undermine cooperation and welfare7,8,9,10. Most previous models of reciprocity do not include inequality11,12,13,14,15. These models assume that individuals are the same in all relevant aspects. Here we introduce a general framework to study direct reciprocity among unequal individuals. Our model allows for multiple sources of inequality. Subjects can differ in their endowments, their productivities and in how much they benefit from public goods. We find that extreme inequality prevents cooperation. But if subjects differ in productivity, some endowment inequality can be necessary for cooperation to prevail. Our mathematical predictions are supported by a behavioural experiment in which we vary the endowments and productivities of the subjects. We observe that overall welfare is maximized when the two sources of heterogeneity are aligned, such that more productive individuals receive higher endowments. By contrast, when endowments and productivities are misaligned, cooperation quickly breaks down. Our findings have implications for policy-makers concerned with equity, efficiency and the provisioning of public goods.","lang":"eng"}],"page":"524-527","file":[{"date_updated":"2020-07-14T12:47:42Z","file_id":"7828","file_size":18577756,"access_level":"open_access","creator":"dernst","content_type":"application/pdf","relation":"main_file","checksum":"a6e0e3168bf62de624e7772cdfaeb26f","date_created":"2020-05-14T10:00:32Z","file_name":"2019_Nature_Hauser.pdf"}],"isi":1,"doi":"10.1038/s41586-019-1488-5","project":[{"grant_number":"279307","name":"Quantitative Graph Games: Theory and Applications","_id":"2581B60A-B435-11E9-9278-68D0E5697425","call_identifier":"FP7"},{"call_identifier":"FWF","grant_number":"S 11407_N23","_id":"25832EC2-B435-11E9-9278-68D0E5697425","name":"Rigorous Systems Engineering"},{"call_identifier":"FP7","grant_number":"291734","_id":"25681D80-B435-11E9-9278-68D0E5697425","name":"International IST Postdoc Fellowship Programme"}],"day":"22","publisher":"Springer Nature","publication":"Nature","department":[{"_id":"KrCh"}],"citation":{"ieee":"O. P. Hauser, C. Hilbe, K. Chatterjee, and M. A. Nowak, “Social dilemmas among unequals,” <i>Nature</i>, vol. 572, no. 7770. Springer Nature, pp. 524–527, 2019.","ama":"Hauser OP, Hilbe C, Chatterjee K, Nowak MA. Social dilemmas among unequals. <i>Nature</i>. 2019;572(7770):524-527. doi:<a href=\"https://doi.org/10.1038/s41586-019-1488-5\">10.1038/s41586-019-1488-5</a>","ista":"Hauser OP, Hilbe C, Chatterjee K, Nowak MA. 2019. Social dilemmas among unequals. Nature. 572(7770), 524–527.","apa":"Hauser, O. P., Hilbe, C., Chatterjee, K., &#38; Nowak, M. A. (2019). Social dilemmas among unequals. <i>Nature</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41586-019-1488-5\">https://doi.org/10.1038/s41586-019-1488-5</a>","mla":"Hauser, Oliver P., et al. “Social Dilemmas among Unequals.” <i>Nature</i>, vol. 572, no. 7770, Springer Nature, 2019, pp. 524–27, doi:<a href=\"https://doi.org/10.1038/s41586-019-1488-5\">10.1038/s41586-019-1488-5</a>.","short":"O.P. Hauser, C. Hilbe, K. Chatterjee, M.A. Nowak, Nature 572 (2019) 524–527.","chicago":"Hauser, Oliver P., Christian Hilbe, Krishnendu Chatterjee, and Martin A. Nowak. “Social Dilemmas among Unequals.” <i>Nature</i>. Springer Nature, 2019. <a href=\"https://doi.org/10.1038/s41586-019-1488-5\">https://doi.org/10.1038/s41586-019-1488-5</a>."},"title":"Social dilemmas among unequals","related_material":{"link":[{"relation":"press_release","url":"https://ist.ac.at/en/news/too-much-inequality-impedes-support-for-public-goods-according-to-research-published-in-nature/","description":"News on IST Homepage"}]},"article_type":"letter_note","publication_status":"published","intvolume":"       572","month":"08","external_id":{"isi":["000482219600045"]},"language":[{"iso":"eng"}],"status":"public","file_date_updated":"2020-07-14T12:47:42Z","_id":"6836","oa_version":"Submitted Version","article_processing_charge":"No","author":[{"last_name":"Hauser","full_name":"Hauser, Oliver P.","first_name":"Oliver P."},{"orcid":"0000-0001-5116-955X","full_name":"Hilbe, Christian","first_name":"Christian","id":"2FDF8F3C-F248-11E8-B48F-1D18A9856A87","last_name":"Hilbe"},{"id":"2E5DCA20-F248-11E8-B48F-1D18A9856A87","last_name":"Chatterjee","orcid":"0000-0002-4561-241X","full_name":"Chatterjee, Krishnendu","first_name":"Krishnendu"},{"first_name":"Martin A.","full_name":"Nowak, Martin A.","last_name":"Nowak"}],"quality_controlled":"1","has_accepted_license":"1","date_published":"2019-08-22T00:00:00Z","publication_identifier":{"eissn":["14764687"],"issn":["00280836"]},"volume":572,"type":"journal_article","date_created":"2019-09-01T22:00:56Z","oa":1,"ec_funded":1,"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","date_updated":"2023-08-29T07:42:54Z","scopus_import":"1","year":"2019"},{"date_created":"2019-09-01T22:00:57Z","type":"journal_article","volume":21,"publication_identifier":{"eissn":["1476-4679"]},"date_published":"2019-08-01T00:00:00Z","year":"2019","scopus_import":"1","date_updated":"2023-08-29T07:42:20Z","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","_id":"6837","oa_version":"None","status":"public","language":[{"iso":"eng"}],"external_id":{"isi":["000478029000003"],"pmid":["31371826"]},"publication_status":"published","month":"08","intvolume":"        21","quality_controlled":"1","author":[{"first_name":"Ste","full_name":"Tavano, Ste","orcid":"0000-0001-9970-7804","last_name":"Tavano","id":"2F162F0C-F248-11E8-B48F-1D18A9856A87"},{"orcid":"0000-0002-0912-4566","full_name":"Heisenberg, Carl-Philipp J","first_name":"Carl-Philipp J","id":"39427864-F248-11E8-B48F-1D18A9856A87","last_name":"Heisenberg"}],"article_processing_charge":"No","doi":"10.1038/s41556-019-0369-3","isi":1,"title":"Migrasomes take center stage","citation":{"ista":"Tavano S, Heisenberg C-PJ. 2019. Migrasomes take center stage. Nature Cell Biology. 21(8), 918–920.","ieee":"S. Tavano and C.-P. J. Heisenberg, “Migrasomes take center stage,” <i>Nature Cell Biology</i>, vol. 21, no. 8. Springer Nature, pp. 918–920, 2019.","ama":"Tavano S, Heisenberg C-PJ. Migrasomes take center stage. <i>Nature Cell Biology</i>. 2019;21(8):918-920. doi:<a href=\"https://doi.org/10.1038/s41556-019-0369-3\">10.1038/s41556-019-0369-3</a>","chicago":"Tavano, Ste, and Carl-Philipp J Heisenberg. “Migrasomes Take Center Stage.” <i>Nature Cell Biology</i>. Springer Nature, 2019. <a href=\"https://doi.org/10.1038/s41556-019-0369-3\">https://doi.org/10.1038/s41556-019-0369-3</a>.","short":"S. Tavano, C.-P.J. Heisenberg, Nature Cell Biology 21 (2019) 918–920.","mla":"Tavano, Ste, and Carl-Philipp J. Heisenberg. “Migrasomes Take Center Stage.” <i>Nature Cell Biology</i>, vol. 21, no. 8, Springer Nature, 2019, pp. 918–20, doi:<a href=\"https://doi.org/10.1038/s41556-019-0369-3\">10.1038/s41556-019-0369-3</a>.","apa":"Tavano, S., &#38; Heisenberg, C.-P. J. (2019). Migrasomes take center stage. <i>Nature Cell Biology</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41556-019-0369-3\">https://doi.org/10.1038/s41556-019-0369-3</a>"},"department":[{"_id":"CaHe"}],"publication":"Nature Cell Biology","publisher":"Springer Nature","day":"01","issue":"8","pmid":1,"page":"918-920","abstract":[{"lang":"eng","text":"Migrasomes are a recently discovered type of extracellular vesicles that are characteristically generated along retraction fibers in migrating cells. Two studies now show how migrasomes are formed and how they function in the physiologically relevant context of the developing zebrafish embryo."}]},{"day":"13","project":[{"_id":"2564DBCA-B435-11E9-9278-68D0E5697425","name":"International IST Doctoral Program","grant_number":"665385","call_identifier":"H2020"}],"department":[{"_id":"RoSe"}],"main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1810.02209"}],"publisher":"IOP Publishing","publication":"Journal of Statistical Mechanics: Theory and Experiment","citation":{"apa":"Mysliwy, K., &#38; Napiórkowski, M. (2019). Thermodynamics of inhomogeneous imperfect quantum gases in harmonic traps. <i>Journal of Statistical Mechanics: Theory and Experiment</i>. IOP Publishing. <a href=\"https://doi.org/10.1088/1742-5468/ab190d\">https://doi.org/10.1088/1742-5468/ab190d</a>","mla":"Mysliwy, Krzysztof, and Marek Napiórkowski. “Thermodynamics of Inhomogeneous Imperfect Quantum Gases in Harmonic Traps.” <i>Journal of Statistical Mechanics: Theory and Experiment</i>, vol. 2019, no. 6, 063101, IOP Publishing, 2019, doi:<a href=\"https://doi.org/10.1088/1742-5468/ab190d\">10.1088/1742-5468/ab190d</a>.","short":"K. Mysliwy, M. Napiórkowski, Journal of Statistical Mechanics: Theory and Experiment 2019 (2019).","chicago":"Mysliwy, Krzysztof, and Marek Napiórkowski. “Thermodynamics of Inhomogeneous Imperfect Quantum Gases in Harmonic Traps.” <i>Journal of Statistical Mechanics: Theory and Experiment</i>. IOP Publishing, 2019. <a href=\"https://doi.org/10.1088/1742-5468/ab190d\">https://doi.org/10.1088/1742-5468/ab190d</a>.","ama":"Mysliwy K, Napiórkowski M. Thermodynamics of inhomogeneous imperfect quantum gases in harmonic traps. <i>Journal of Statistical Mechanics: Theory and Experiment</i>. 2019;2019(6). doi:<a href=\"https://doi.org/10.1088/1742-5468/ab190d\">10.1088/1742-5468/ab190d</a>","ieee":"K. Mysliwy and M. Napiórkowski, “Thermodynamics of inhomogeneous imperfect quantum gases in harmonic traps,” <i>Journal of Statistical Mechanics: Theory and Experiment</i>, vol. 2019, no. 6. IOP Publishing, 2019.","ista":"Mysliwy K, Napiórkowski M. 2019. Thermodynamics of inhomogeneous imperfect quantum gases in harmonic traps. Journal of Statistical Mechanics: Theory and Experiment. 2019(6), 063101."},"title":"Thermodynamics of inhomogeneous imperfect quantum gases in harmonic traps","doi":"10.1088/1742-5468/ab190d","isi":1,"abstract":[{"lang":"eng","text":"We discuss thermodynamic properties of harmonically trapped\r\nimperfect quantum gases. The spatial inhomogeneity of these systems imposes\r\na redefinition of the mean-field interparticle potential energy as compared\r\nto the homogeneous case. In our approach, it takes the form a\r\n2N2 ωd, where\r\nN is the number of particles, ω—the harmonic trap frequency, d—system’s\r\ndimensionality, and a is a parameter characterizing the interparticle interaction.\r\nWe provide arguments that this model corresponds to the limiting case of\r\na long-ranged interparticle potential of vanishingly small amplitude. This\r\nconclusion is drawn from a computation similar to the well-known Kac scaling\r\nprocedure, which is presented here in a form adapted to the case of an isotropic\r\nharmonic trap. We show that within the model, the imperfect gas of trapped\r\nrepulsive bosons undergoes the Bose–Einstein condensation provided d > 1.\r\nThe main result of our analysis is that in d = 1 the gas of attractive imperfect\r\nfermions with a = −aF < 0 is thermodynamically equivalent to the gas of\r\nrepulsive bosons with a = aB > 0 provided the parameters aF and aB fulfill\r\nthe relation aB + aF = \u001f. This result supplements similar recent conclusion\r\nabout thermodynamic equivalence of two-dimensional (2D) uniform imperfect\r\nrepulsive Bose and attractive Fermi gases."}],"issue":"6","article_number":"063101","oa":1,"ec_funded":1,"scopus_import":"1","date_updated":"2023-08-29T07:19:13Z","arxiv":1,"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","year":"2019","date_published":"2019-06-13T00:00:00Z","volume":2019,"publication_identifier":{"eissn":["1742-5468"]},"date_created":"2019-09-01T22:00:59Z","type":"journal_article","article_processing_charge":"No","author":[{"id":"316457FC-F248-11E8-B48F-1D18A9856A87","last_name":"Mysliwy","full_name":"Mysliwy, Krzysztof","first_name":"Krzysztof"},{"full_name":"Napiórkowski, Marek","first_name":"Marek","last_name":"Napiórkowski"}],"quality_controlled":"1","language":[{"iso":"eng"}],"external_id":{"isi":["000471650100001"],"arxiv":["1810.02209"]},"month":"06","publication_status":"published","intvolume":"      2019","_id":"6840","oa_version":"Preprint","status":"public"},{"isi":1,"doi":"10.1016/j.jmaa.2019.123435","title":"On isometric embeddings of Wasserstein spaces – the discrete case","citation":{"chicago":"Gehér, György Pál, Tamás Titkos, and Daniel Virosztek. “On Isometric Embeddings of Wasserstein Spaces – the Discrete Case.” <i>Journal of Mathematical Analysis and Applications</i>. Elsevier, 2019. <a href=\"https://doi.org/10.1016/j.jmaa.2019.123435\">https://doi.org/10.1016/j.jmaa.2019.123435</a>.","mla":"Gehér, György Pál, et al. “On Isometric Embeddings of Wasserstein Spaces – the Discrete Case.” <i>Journal of Mathematical Analysis and Applications</i>, vol. 480, no. 2, 123435, Elsevier, 2019, doi:<a href=\"https://doi.org/10.1016/j.jmaa.2019.123435\">10.1016/j.jmaa.2019.123435</a>.","short":"G.P. Gehér, T. Titkos, D. Virosztek, Journal of Mathematical Analysis and Applications 480 (2019).","apa":"Gehér, G. P., Titkos, T., &#38; Virosztek, D. (2019). On isometric embeddings of Wasserstein spaces – the discrete case. <i>Journal of Mathematical Analysis and Applications</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.jmaa.2019.123435\">https://doi.org/10.1016/j.jmaa.2019.123435</a>","ista":"Gehér GP, Titkos T, Virosztek D. 2019. On isometric embeddings of Wasserstein spaces – the discrete case. Journal of Mathematical Analysis and Applications. 480(2), 123435.","ieee":"G. P. Gehér, T. Titkos, and D. Virosztek, “On isometric embeddings of Wasserstein spaces – the discrete case,” <i>Journal of Mathematical Analysis and Applications</i>, vol. 480, no. 2. Elsevier, 2019.","ama":"Gehér GP, Titkos T, Virosztek D. On isometric embeddings of Wasserstein spaces – the discrete case. <i>Journal of Mathematical Analysis and Applications</i>. 2019;480(2). doi:<a href=\"https://doi.org/10.1016/j.jmaa.2019.123435\">10.1016/j.jmaa.2019.123435</a>"},"publication":"Journal of Mathematical Analysis and Applications","publisher":"Elsevier","department":[{"_id":"LaEr"}],"main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1809.01101"}],"day":"15","project":[{"grant_number":"291734","_id":"25681D80-B435-11E9-9278-68D0E5697425","name":"International IST Postdoc Fellowship Programme","call_identifier":"FP7"}],"article_number":"123435","issue":"2","abstract":[{"text":"The aim of this short paper is to offer a complete characterization of all (not necessarily surjective) isometric embeddings of the Wasserstein space Wp(X), where S is a countable discrete metric space and 0<p<∞ is any parameter value. Roughly speaking, we will prove that any isometric embedding can be described by a special kind of X×(0,1]-indexed family of nonnegative finite measures. Our result implies that a typical non-surjective isometric embedding of Wp(X) splits mass and does not preserve the shape of measures. In order to stress that the lack of surjectivity is what makes things challenging, we will prove alternatively that Wp(X) is isometrically rigid for all 0<p<∞.","lang":"eng"}],"type":"journal_article","date_created":"2019-09-01T22:01:01Z","publication_identifier":{"issn":["0022247X"],"eissn":["10960813"]},"volume":480,"date_published":"2019-12-15T00:00:00Z","year":"2019","arxiv":1,"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","date_updated":"2023-08-29T07:18:50Z","scopus_import":"1","ec_funded":1,"oa":1,"status":"public","oa_version":"Preprint","_id":"6843","month":"12","external_id":{"arxiv":["1809.01101"],"isi":["000486563900031"]},"publication_status":"published","intvolume":"       480","language":[{"iso":"eng"}],"article_type":"original","quality_controlled":"1","author":[{"full_name":"Gehér, György Pál","first_name":"György Pál","last_name":"Gehér"},{"first_name":"Tamás","full_name":"Titkos, Tamás","last_name":"Titkos"},{"last_name":"Virosztek","id":"48DB45DA-F248-11E8-B48F-1D18A9856A87","first_name":"Daniel","full_name":"Virosztek, Daniel","orcid":"0000-0003-1109-5511"}],"article_processing_charge":"No"},{"ddc":["570"],"issue":"3","page":"686-696","file":[{"file_size":1192994,"file_id":"6845","date_updated":"2020-07-14T12:47:42Z","checksum":"160f960844b204057f20896e0e1f8ee7","relation":"main_file","access_level":"open_access","content_type":"application/pdf","creator":"dernst","date_created":"2019-09-02T12:05:18Z","file_name":"2019_JournalAnatomy_Picco.pdf"}],"abstract":[{"text":"Studying the progression of the proliferative and differentiative patterns of neural stem cells at the individual cell level is crucial to the understanding of cortex development and how the disruption of such patterns can lead to malformations and neurodevelopmental diseases. However, our understanding of the precise lineage progression programme at single-cell resolution is still incomplete due to the technical variations in lineage- tracing approaches. One of the key challenges involves developing a robust theoretical framework in which we can integrate experimental observations and introduce correction factors to obtain a reliable and representative description of the temporal modulation of proliferation and differentiation. In order to obtain more conclusive insights, we carry out virtual clonal analysis using mathematical modelling and compare our results against experimental data. Using a dataset obtained with Mosaic Analysis with Double Markers, we illustrate how the theoretical description can be exploited to interpret and reconcile the disparity between virtual and experimental results.","lang":"eng"}],"doi":"10.1111/joa.13001","isi":1,"citation":{"ista":"Picco N, Hippenmeyer S, Rodarte J, Streicher C, Molnár Z, Maini PK, Woolley TE. 2019. A mathematical insight into cell labelling experiments for clonal analysis. Journal of Anatomy. 235(3), 686–696.","ama":"Picco N, Hippenmeyer S, Rodarte J, et al. A mathematical insight into cell labelling experiments for clonal analysis. <i>Journal of Anatomy</i>. 2019;235(3):686-696. doi:<a href=\"https://doi.org/10.1111/joa.13001\">10.1111/joa.13001</a>","ieee":"N. Picco <i>et al.</i>, “A mathematical insight into cell labelling experiments for clonal analysis,” <i>Journal of Anatomy</i>, vol. 235, no. 3. Wiley, pp. 686–696, 2019.","chicago":"Picco, Noemi, Simon Hippenmeyer, Julio Rodarte, Carmen Streicher, Zoltán Molnár, Philip K. Maini, and Thomas E. Woolley. “A Mathematical Insight into Cell Labelling Experiments for Clonal Analysis.” <i>Journal of Anatomy</i>. Wiley, 2019. <a href=\"https://doi.org/10.1111/joa.13001\">https://doi.org/10.1111/joa.13001</a>.","short":"N. Picco, S. Hippenmeyer, J. Rodarte, C. Streicher, Z. Molnár, P.K. Maini, T.E. Woolley, Journal of Anatomy 235 (2019) 686–696.","mla":"Picco, Noemi, et al. “A Mathematical Insight into Cell Labelling Experiments for Clonal Analysis.” <i>Journal of Anatomy</i>, vol. 235, no. 3, Wiley, 2019, pp. 686–96, doi:<a href=\"https://doi.org/10.1111/joa.13001\">10.1111/joa.13001</a>.","apa":"Picco, N., Hippenmeyer, S., Rodarte, J., Streicher, C., Molnár, Z., Maini, P. K., &#38; Woolley, T. E. (2019). A mathematical insight into cell labelling experiments for clonal analysis. <i>Journal of Anatomy</i>. Wiley. <a href=\"https://doi.org/10.1111/joa.13001\">https://doi.org/10.1111/joa.13001</a>"},"title":"A mathematical insight into cell labelling experiments for clonal analysis","project":[{"call_identifier":"H2020","grant_number":"725780","name":"Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development","_id":"260018B0-B435-11E9-9278-68D0E5697425"}],"day":"01","department":[{"_id":"SiHi"}],"publication":"Journal of Anatomy","publisher":"Wiley","language":[{"iso":"eng"}],"month":"09","intvolume":"       235","external_id":{"isi":["000482426800017"]},"publication_status":"published","oa_version":"Published Version","_id":"6844","status":"public","file_date_updated":"2020-07-14T12:47:42Z","article_type":"original","license":"https://creativecommons.org/licenses/by-nc/4.0/","author":[{"first_name":"Noemi","full_name":"Picco, Noemi","last_name":"Picco"},{"first_name":"Simon","orcid":"0000-0003-2279-1061","full_name":"Hippenmeyer, Simon","last_name":"Hippenmeyer","id":"37B36620-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Julio","full_name":"Rodarte, Julio","last_name":"Rodarte","id":"3C70A038-F248-11E8-B48F-1D18A9856A87"},{"id":"36BCB99C-F248-11E8-B48F-1D18A9856A87","last_name":"Streicher","full_name":"Streicher, Carmen","first_name":"Carmen"},{"last_name":"Molnár","first_name":"Zoltán","full_name":"Molnár, Zoltán"},{"last_name":"Maini","full_name":"Maini, Philip K.","first_name":"Philip K."},{"last_name":"Woolley","full_name":"Woolley, Thomas E.","first_name":"Thomas E."}],"quality_controlled":"1","article_processing_charge":"No","volume":235,"publication_identifier":{"issn":["0021-8782"],"eissn":["1469-7580"]},"date_created":"2019-09-02T11:57:28Z","tmp":{"name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","short":"CC BY-NC (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","image":"/images/cc_by_nc.png"},"type":"journal_article","has_accepted_license":"1","date_published":"2019-09-01T00:00:00Z","scopus_import":"1","date_updated":"2023-08-29T07:19:39Z","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","year":"2019","oa":1,"ec_funded":1},{"has_accepted_license":"1","acknowledged_ssus":[{"_id":"ScienComp"}],"date_published":"2019-09-12T00:00:00Z","publication_identifier":{"eissn":["1476-4687"],"issn":["0028-0836"]},"volume":573,"type":"journal_article","date_created":"2019-09-04T06:21:41Z","oa":1,"ec_funded":1,"date_updated":"2024-03-25T23:30:08Z","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","scopus_import":"1","year":"2019","article_type":"letter_note","month":"09","intvolume":"       573","publication_status":"published","external_id":{"pmid":["31462775"],"isi":["000485415400061"]},"language":[{"iso":"eng"}],"file_date_updated":"2020-11-26T16:33:44Z","status":"public","_id":"6848","oa_version":"Submitted Version","article_processing_charge":"No","acknowledgement":" We thank R. Thompson, G. Effantin and V.-V. Hodirnau for their assistance with collecting NADP+, NADPH and apo datasets, respectively. Data processing was performed at the IST high-performance computing cluster.\r\nThis project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Grant Agreement no. 665385.","author":[{"id":"37233050-F248-11E8-B48F-1D18A9856A87","last_name":"Kampjut","full_name":"Kampjut, Domen","first_name":"Domen"},{"last_name":"Sazanov","id":"338D39FE-F248-11E8-B48F-1D18A9856A87","first_name":"Leonid A","full_name":"Sazanov, Leonid A","orcid":"0000-0002-0977-7989"}],"quality_controlled":"1","isi":1,"doi":"10.1038/s41586-019-1519-2","project":[{"_id":"2564DBCA-B435-11E9-9278-68D0E5697425","name":"International IST Doctoral Program","grant_number":"665385","call_identifier":"H2020"}],"day":"12","publisher":"Springer Nature","publication":"Nature","department":[{"_id":"LeSa"}],"citation":{"short":"D. Kampjut, L.A. Sazanov, Nature 573 (2019) 291–295.","mla":"Kampjut, Domen, and Leonid A. Sazanov. “Structure and Mechanism of Mitochondrial Proton-Translocating Transhydrogenase.” <i>Nature</i>, vol. 573, no. 7773, Springer Nature, 2019, pp. 291–295, doi:<a href=\"https://doi.org/10.1038/s41586-019-1519-2\">10.1038/s41586-019-1519-2</a>.","apa":"Kampjut, D., &#38; Sazanov, L. A. (2019). Structure and mechanism of mitochondrial proton-translocating transhydrogenase. <i>Nature</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41586-019-1519-2\">https://doi.org/10.1038/s41586-019-1519-2</a>","chicago":"Kampjut, Domen, and Leonid A Sazanov. “Structure and Mechanism of Mitochondrial Proton-Translocating Transhydrogenase.” <i>Nature</i>. Springer Nature, 2019. <a href=\"https://doi.org/10.1038/s41586-019-1519-2\">https://doi.org/10.1038/s41586-019-1519-2</a>.","ama":"Kampjut D, Sazanov LA. Structure and mechanism of mitochondrial proton-translocating transhydrogenase. <i>Nature</i>. 2019;573(7773):291–295. doi:<a href=\"https://doi.org/10.1038/s41586-019-1519-2\">10.1038/s41586-019-1519-2</a>","ieee":"D. Kampjut and L. A. Sazanov, “Structure and mechanism of mitochondrial proton-translocating transhydrogenase,” <i>Nature</i>, vol. 573, no. 7773. Springer Nature, pp. 291–295, 2019.","ista":"Kampjut D, Sazanov LA. 2019. Structure and mechanism of mitochondrial proton-translocating transhydrogenase. Nature. 573(7773), 291–295."},"related_material":{"record":[{"id":"8340","status":"public","relation":"dissertation_contains"}],"link":[{"relation":"press_release","url":"https://ist.ac.at/en/news/high-end-microscopy-reveals-structure-and-function-of-crucial-metabolic-enzyme/","description":"News on IST Website"}]},"title":"Structure and mechanism of mitochondrial proton-translocating transhydrogenase","issue":"7773","ddc":["572"],"abstract":[{"lang":"eng","text":"Proton-translocating transhydrogenase (also known as nicotinamide nucleotide transhydrogenase (NNT)) is found in the plasma membranes of bacteria and the inner mitochondrial membranes of eukaryotes. NNT catalyses the transfer of a hydride between NADH and NADP+, coupled to the translocation of one proton across the membrane. Its main physiological function is the generation of NADPH, which is a substrate in anabolic reactions and a regulator of oxidative status; however, NNT may also fine-tune the Krebs cycle1,2. NNT deficiency causes familial glucocorticoid deficiency in humans and metabolic abnormalities in mice, similar to those observed in type II diabetes3,4. The catalytic mechanism of NNT has been proposed to involve a rotation of around 180° of the entire NADP(H)-binding domain that alternately participates in hydride transfer and proton-channel gating. However, owing to the lack of high-resolution structures of intact NNT, the details of this process remain unclear5,6. Here we present the cryo-electron microscopy structure of intact mammalian NNT in different conformational states. We show how the NADP(H)-binding domain opens the proton channel to the opposite sides of the membrane, and we provide structures of these two states. We also describe the catalytically important interfaces and linkers between the membrane and the soluble domains and their roles in nucleotide exchange. These structures enable us to propose a revised mechanism for a coupling process in NNT that is consistent with a large body of previous biochemical work. Our results are relevant to the development of currently unavailable NNT inhibitors, which may have therapeutic potential in ischaemia reperfusion injury, metabolic syndrome and some cancers7,8,9."}],"page":"291–295","file":[{"date_updated":"2020-11-26T16:33:44Z","file_size":3066206,"file_id":"8821","content_type":"application/pdf","access_level":"open_access","creator":"lsazanov","checksum":"52728cda5210a3e9b74cc204e8aed3d5","relation":"main_file","success":1,"date_created":"2020-11-26T16:33:44Z","file_name":"Manuscript_final_acc_withFigs_SI_opt_red.pdf"}],"pmid":1},{"related_material":{"record":[{"id":"5914","status":"public","relation":"part_of_dissertation"}]},"title":"The role of CCK-interneurons in regulating hippocampal network dynamics","citation":{"ista":"Rangel Guerrero DK. 2019. The role of CCK-interneurons in regulating hippocampal network dynamics. Institute of Science and Technology Austria.","ieee":"D. K. Rangel Guerrero, “The role of CCK-interneurons in regulating hippocampal network dynamics,” Institute of Science and Technology Austria, 2019.","ama":"Rangel Guerrero DK. The role of CCK-interneurons in regulating hippocampal network dynamics. 2019. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:6849\">10.15479/AT:ISTA:6849</a>","chicago":"Rangel Guerrero, Dámaris K. “The Role of CCK-Interneurons in Regulating Hippocampal Network Dynamics.” Institute of Science and Technology Austria, 2019. <a href=\"https://doi.org/10.15479/AT:ISTA:6849\">https://doi.org/10.15479/AT:ISTA:6849</a>.","short":"D.K. Rangel Guerrero, The Role of CCK-Interneurons in Regulating Hippocampal Network Dynamics, Institute of Science and Technology Austria, 2019.","mla":"Rangel Guerrero, Dámaris K. <i>The Role of CCK-Interneurons in Regulating Hippocampal Network Dynamics</i>. Institute of Science and Technology Austria, 2019, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:6849\">10.15479/AT:ISTA:6849</a>.","apa":"Rangel Guerrero, D. K. (2019). <i>The role of CCK-interneurons in regulating hippocampal network dynamics</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:6849\">https://doi.org/10.15479/AT:ISTA:6849</a>"},"department":[{"_id":"JoCs"}],"publisher":"Institute of Science and Technology Austria","day":"09","doi":"10.15479/AT:ISTA:6849","file":[{"embargo_to":"open_access","file_name":"Thesis_Damaris_Rangel_source.docx","date_created":"2019-09-09T13:09:45Z","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","access_level":"closed","creator":"drangel","checksum":"244dc4f74dbfc94f414156092298831f","relation":"source_file","date_updated":"2021-02-10T23:30:09Z","file_size":18253100,"file_id":"6865"},{"checksum":"59c73be40eeaa1c4db24067270151555","relation":"main_file","content_type":"application/pdf","creator":"drangel","access_level":"open_access","file_size":2160109,"request_a_copy":0,"file_id":"6866","date_updated":"2020-09-11T22:30:04Z","file_name":"Thesis_Damaris_Rangel_pdfa.pdf","embargo":"2020-09-10","date_created":"2019-09-09T13:09:52Z"}],"page":"97","abstract":[{"text":"Brain function is mediated by complex dynamical interactions between excitatory and inhibitory cell types. The Cholecystokinin-expressing inhibitory cells (CCK-interneurons) are one of the least studied types, despite being suspected to play important roles in cognitive processes. We studied the network effects of optogenetic silencing of CCK-interneurons in the CA1 hippocampal area during exploration and sleep states. The cell firing pattern in response to light pulses allowed us to classify the recorded neurons in 5 classes, including disinhibited and non-responsive pyramidal cell and interneurons, and the inhibited interneurons corresponding to the CCK group. The light application, which inhibited the activity of CCK interneurons triggered wider changes in the firing dynamics of cells. We observed rate changes (i.e. remapping) of pyramidal cells during the exploration session in which the light was applied relative to the previous control session that was not restricted neither in time nor space to the light delivery. Also, the disinhibited pyramidal cells had higher increase in bursting than in single spike firing rate as a result of CCK silencing. In addition, the firing activity patterns during exploratory periods were more weakly reactivated in sleep for those periods in which CCK-interneuron were silenced than in the unaffected periods. Furthermore, light pulses during sleep disrupted the reactivation of recent waking patterns. Hence, silencing CCK neurons during exploration suppressed the reactivation of waking firing patterns in sleep and CCK interneuron activity was also required during sleep for the normal reactivation of waking patterns. These findings demonstrate the involvement of CCK cells in reactivation-related memory consolidation. An important part of our analysis was to test the relationship of the identified CCKinterneurons to brain oscillations. Our findings showed that these cells exhibited different oscillatory behaviour during anaesthesia and natural waking and sleep conditions. We showed that: 1) Contrary to the past studies performed under anaesthesia, the identified CCKinterneurons fired on the descending portion of the theta phase in waking exploration. 2) CCKinterneuron preferred phases around the trough of gamma oscillations. 3) Contrary to anaesthesia conditions, the average firing rate of the CCK-interneurons increased around the peak activity of the sharp-wave ripple (SWR) events in natural sleep, which is congruent with new reports about their functional connectivity. We also found that light driven CCK-interneuron silencing altered the dynamics on the CA1 network oscillatory activity: 1) Pyramidal cells negatively shifted their preferred theta phases when the light was applied, while interneurons responses were less consistent. 2) As a population, pyramidal cells negatively shifted their preferred activity during gamma oscillations, albeit we did not find gamma modulation differences related to the light application when pyramidal cells were subdivided into the disinhibited and unaffected groups. 3) During the peak of SWR events, all but the CCK-interneurons had a reduction in their relative firing rate change during the light application as compared to the change observed at SWR initiation. Finally, regarding to the place field activity of the recorded pyramidal neurons, we showed that the disinhibited pyramidal cells had reduced place field similarity, coherence and spatial information, but only during the light application. The mechanisms behind such observed behaviours might involve eCB signalling and plastic changes in CCK-interneuron synapses. In conclusion, the observed changes related to the light-mediated silencing of CCKinterneurons have unravelled characteristics of this interneuron subpopulation that might change the understanding not only of their particular network interactions, but also of the current theories about the emergence of certain cognitive processes such as place coding needed for navigation or hippocampus-dependent memory consolidation. ","lang":"eng"}],"ddc":["570"],"degree_awarded":"PhD","year":"2019","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","date_updated":"2023-09-19T10:01:12Z","supervisor":[{"orcid":"0000-0002-5193-4036","full_name":"Csicsvari, Jozsef L","first_name":"Jozsef L","id":"3FA14672-F248-11E8-B48F-1D18A9856A87","last_name":"Csicsvari"}],"oa":1,"date_created":"2019-09-06T06:54:16Z","type":"dissertation","publication_identifier":{"isbn":["9783990780039"],"issn":["2663-337X"]},"date_published":"2019-09-09T00:00:00Z","acknowledged_ssus":[{"_id":"Bio"},{"_id":"PreCl"},{"_id":"M-Shop"}],"has_accepted_license":"1","author":[{"id":"4871BCE6-F248-11E8-B48F-1D18A9856A87","last_name":"Rangel Guerrero","full_name":"Rangel Guerrero, Dámaris K","orcid":"0000-0002-8602-4374","first_name":"Dámaris K"}],"article_processing_charge":"No","alternative_title":["ISTA Thesis"],"_id":"6849","oa_version":"Published Version","status":"public","file_date_updated":"2021-02-10T23:30:09Z","language":[{"iso":"eng"}],"month":"09","publication_status":"published"},{"file_date_updated":"2020-07-14T12:47:42Z","status":"public","oa_version":"Published Version","_id":"6855","month":"07","external_id":{"isi":["000485148400020"],"pmid":["31283361"]},"intvolume":"        20","publication_status":"published","language":[{"iso":"eng"}],"article_processing_charge":"No","quality_controlled":"1","author":[{"last_name":"Sella","first_name":"Guy","full_name":"Sella, Guy"},{"id":"4880FE40-F248-11E8-B48F-1D18A9856A87","last_name":"Barton","orcid":"0000-0002-8548-5240","full_name":"Barton, Nicholas H","first_name":"Nicholas H"}],"date_published":"2019-07-05T00:00:00Z","has_accepted_license":"1","type":"journal_article","date_created":"2019-09-07T14:28:29Z","tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"publication_identifier":{"eissn":["1545-293X"],"issn":["1527-8204"]},"volume":20,"oa":1,"year":"2019","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","date_updated":"2023-08-29T07:49:38Z","scopus_import":"1","ddc":["576"],"abstract":[{"lang":"eng","text":"Many traits of interest are highly heritable and genetically complex, meaning that much of the variation they exhibit arises from differences at numerous loci in the genome. Complex traits and their evolution have been studied for more than a century, but only in the last decade have genome-wide association studies (GWASs) in humans begun to reveal their genetic basis. Here, we bring these threads of research together to ask how findings from GWASs can further our understanding of the processes that give rise to heritable variation in complex traits and of the genetic basis of complex trait evolution in response to changing selection pressures (i.e., of polygenic adaptation). Conversely, we ask how evolutionary thinking helps us to interpret findings from GWASs and informs related efforts of practical importance."}],"pmid":1,"file":[{"date_created":"2019-09-09T07:22:12Z","file_name":"2019_AnnualReview_Sella.pdf","date_updated":"2020-07-14T12:47:42Z","file_size":411491,"file_id":"6862","content_type":"application/pdf","creator":"dernst","access_level":"open_access","checksum":"23d3978cf4739a89ce2c3e779f9305ca","relation":"main_file"}],"page":"461-493","isi":1,"doi":"10.1146/annurev-genom-083115-022316","publication":"Annual Review of Genomics and Human Genetics","publisher":"Annual Reviews","department":[{"_id":"NiBa"}],"day":"05","title":"Thinking about the evolution of complex traits in the era of genome-wide association studies","citation":{"chicago":"Sella, Guy, and Nicholas H Barton. “Thinking about the Evolution of Complex Traits in the Era of Genome-Wide Association Studies.” <i>Annual Review of Genomics and Human Genetics</i>. Annual Reviews, 2019. <a href=\"https://doi.org/10.1146/annurev-genom-083115-022316\">https://doi.org/10.1146/annurev-genom-083115-022316</a>.","apa":"Sella, G., &#38; Barton, N. H. (2019). Thinking about the evolution of complex traits in the era of genome-wide association studies. <i>Annual Review of Genomics and Human Genetics</i>. Annual Reviews. <a href=\"https://doi.org/10.1146/annurev-genom-083115-022316\">https://doi.org/10.1146/annurev-genom-083115-022316</a>","mla":"Sella, Guy, and Nicholas H. Barton. “Thinking about the Evolution of Complex Traits in the Era of Genome-Wide Association Studies.” <i>Annual Review of Genomics and Human Genetics</i>, vol. 20, Annual Reviews, 2019, pp. 461–93, doi:<a href=\"https://doi.org/10.1146/annurev-genom-083115-022316\">10.1146/annurev-genom-083115-022316</a>.","short":"G. Sella, N.H. Barton, Annual Review of Genomics and Human Genetics 20 (2019) 461–493.","ista":"Sella G, Barton NH. 2019. Thinking about the evolution of complex traits in the era of genome-wide association studies. Annual Review of Genomics and Human Genetics. 20, 461–493.","ama":"Sella G, Barton NH. Thinking about the evolution of complex traits in the era of genome-wide association studies. <i>Annual Review of Genomics and Human Genetics</i>. 2019;20:461-493. doi:<a href=\"https://doi.org/10.1146/annurev-genom-083115-022316\">10.1146/annurev-genom-083115-022316</a>","ieee":"G. Sella and N. H. Barton, “Thinking about the evolution of complex traits in the era of genome-wide association studies,” <i>Annual Review of Genomics and Human Genetics</i>, vol. 20. Annual Reviews, pp. 461–493, 2019."}},{"abstract":[{"text":"Plant mating systems play a key role in structuring genetic variation both within and between species. In hybrid zones, the outcomes and dynamics of hybridization are usually interpreted as the balance between gene flow and selection against hybrids. Yet, mating systems can introduce selective forces that alter these expectations; with diverse outcomes for the level and direction of gene flow depending on variation in outcrossing and whether the mating systems of the species pair are the same or divergent. We present a survey of hybridization in 133 species pairs from 41 plant families and examine how patterns of hybridization vary with mating system. We examine if hybrid zone mode, level of gene flow, asymmetries in gene flow and the frequency of reproductive isolating barriers vary in relation to mating system/s of the species pair. We combine these results with a simulation model and examples from the literature to address two general themes: (i) the two‐way interaction between introgression and the evolution of reproductive systems, and (ii) how mating system can facilitate or restrict interspecific gene flow. We conclude that examining mating system with hybridization provides unique opportunities to understand divergence and the processes underlying reproductive isolation.","lang":"eng"}],"file":[{"file_id":"7011","file_size":1511958,"date_updated":"2020-07-14T12:47:42Z","relation":"main_file","checksum":"21e4c95599bbcaf7c483b89954658672","content_type":"application/pdf","creator":"dernst","access_level":"open_access","date_created":"2019-11-13T08:15:05Z","file_name":"2019_NewPhytologist_Pickup.pdf"}],"pmid":1,"page":"1035-1047","issue":"3","ddc":["570"],"department":[{"_id":"NiBa"}],"publication":"New Phytologist","publisher":"Wiley","day":"01","project":[{"name":"Mating system and the evolutionary dynamics of hybrid zones","_id":"25B36484-B435-11E9-9278-68D0E5697425","grant_number":"329960","call_identifier":"FP7"},{"_id":"2662AADE-B435-11E9-9278-68D0E5697425","name":"Sex chromosomes and species barriers","grant_number":"M02463","call_identifier":"FWF"}],"title":"Mating system variation in hybrid zones: Facilitation, barriers and asymmetries to gene flow","citation":{"apa":"Pickup, M., Barton, N. H., Brandvain, Y., Fraisse, C., Yakimowski, S., Dixit, T., … Field, D. (2019). Mating system variation in hybrid zones: Facilitation, barriers and asymmetries to gene flow. <i>New Phytologist</i>. Wiley. <a href=\"https://doi.org/10.1111/nph.16180\">https://doi.org/10.1111/nph.16180</a>","mla":"Pickup, Melinda, et al. “Mating System Variation in Hybrid Zones: Facilitation, Barriers and Asymmetries to Gene Flow.” <i>New Phytologist</i>, vol. 224, no. 3, Wiley, 2019, pp. 1035–47, doi:<a href=\"https://doi.org/10.1111/nph.16180\">10.1111/nph.16180</a>.","short":"M. Pickup, N.H. Barton, Y. Brandvain, C. Fraisse, S. Yakimowski, T. Dixit, C. Lexer, E. Cereghetti, D. Field, New Phytologist 224 (2019) 1035–1047.","chicago":"Pickup, Melinda, Nicholas H Barton, Yaniv Brandvain, Christelle Fraisse, Sarah Yakimowski, Tanmay Dixit, Christian Lexer, Eva Cereghetti, and David Field. “Mating System Variation in Hybrid Zones: Facilitation, Barriers and Asymmetries to Gene Flow.” <i>New Phytologist</i>. Wiley, 2019. <a href=\"https://doi.org/10.1111/nph.16180\">https://doi.org/10.1111/nph.16180</a>.","ama":"Pickup M, Barton NH, Brandvain Y, et al. Mating system variation in hybrid zones: Facilitation, barriers and asymmetries to gene flow. <i>New Phytologist</i>. 2019;224(3):1035-1047. doi:<a href=\"https://doi.org/10.1111/nph.16180\">10.1111/nph.16180</a>","ieee":"M. Pickup <i>et al.</i>, “Mating system variation in hybrid zones: Facilitation, barriers and asymmetries to gene flow,” <i>New Phytologist</i>, vol. 224, no. 3. Wiley, pp. 1035–1047, 2019.","ista":"Pickup M, Barton NH, Brandvain Y, Fraisse C, Yakimowski S, Dixit T, Lexer C, Cereghetti E, Field D. 2019. Mating system variation in hybrid zones: Facilitation, barriers and asymmetries to gene flow. New Phytologist. 224(3), 1035–1047."},"doi":"10.1111/nph.16180","article_processing_charge":"No","quality_controlled":"1","author":[{"first_name":"Melinda","full_name":"Pickup, Melinda","orcid":"0000-0001-6118-0541","last_name":"Pickup","id":"2C78037E-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Barton, Nicholas H","orcid":"0000-0002-8548-5240","first_name":"Nicholas H","id":"4880FE40-F248-11E8-B48F-1D18A9856A87","last_name":"Barton"},{"last_name":"Brandvain","full_name":"Brandvain, Yaniv","first_name":"Yaniv"},{"first_name":"Christelle","orcid":"0000-0001-8441-5075","full_name":"Fraisse, Christelle","last_name":"Fraisse","id":"32DF5794-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Yakimowski","first_name":"Sarah","full_name":"Yakimowski, Sarah"},{"last_name":"Dixit","first_name":"Tanmay","full_name":"Dixit, Tanmay"},{"last_name":"Lexer","first_name":"Christian","full_name":"Lexer, Christian"},{"first_name":"Eva","full_name":"Cereghetti, Eva","last_name":"Cereghetti","id":"71AA91B4-05ED-11EA-8BEB-F5833E63BD63"},{"orcid":"0000-0002-4014-8478","full_name":"Field, David","first_name":"David","id":"419049E2-F248-11E8-B48F-1D18A9856A87","last_name":"Field"}],"article_type":"original","_id":"6856","oa_version":"Published Version","file_date_updated":"2020-07-14T12:47:42Z","status":"public","language":[{"iso":"eng"}],"publication_status":"published","month":"11","external_id":{"pmid":["31505037"]},"intvolume":"       224","ec_funded":1,"oa":1,"year":"2019","scopus_import":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2023-10-18T08:47:08Z","date_published":"2019-11-01T00:00:00Z","has_accepted_license":"1","date_created":"2019-09-07T14:35:40Z","tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"type":"journal_article","volume":224,"publication_identifier":{"eissn":["1469-8137"],"issn":["0028-646X"]}},{"issue":"11","article_number":"1900151","ddc":["570"],"abstract":[{"text":"Gene Drives are regarded as future tools with a high potential for population control. Due to their inherent ability to overcome the rules of Mendelian inheritance, gene drives (GD) may spread genes rapidly through populations of sexually reproducing organisms. A release of organisms carrying a GD would constitute a paradigm shift in the handling of genetically modified organisms because gene drive organisms (GDO) are designed to drive their transgenes into wild populations and thereby increase the number of GDOs. The rapid development in this field and its focus on wild populations demand a prospective risk assessment with a focus on exposure related aspects. Presently, it is unclear how adequate risk management could be guaranteed to limit the spread of GDs in time and space, in order to avoid potential adverse effects in socio‐ecological systems.\r\n\r\nThe recent workshop on the “Evaluation of Spatial and Temporal Control of Gene Drives” hosted by the Institute of Safety/Security and Risk Sciences (ISR) in Vienna aimed at gaining some insight into the potential population dynamic behavior of GDs and appropriate measures of control. Scientists from France, Germany, England, and the USA discussed both topics in this meeting on April 4–5, 2019. This article summarizes results of the workshop.","lang":"eng"}],"file":[{"file_name":"2019_BioEssays_Giese.pdf","date_created":"2019-10-11T06:59:26Z","creator":"dernst","access_level":"open_access","content_type":"application/pdf","checksum":"8cc7551bff70b2658f8d5630f228ee12","relation":"main_file","date_updated":"2020-07-14T12:47:42Z","file_size":193248,"file_id":"6939"}],"doi":"10.1002/bies.201900151","isi":1,"day":"01","department":[{"_id":"NiBa"}],"publisher":"Wiley","publication":"BioEssays","citation":{"chicago":"Giese, B, J L Friess, M F  Schetelig, Nicholas H Barton, Philip Messer, Florence Debarre, H Meimberg, N Windbichler, and C Boete. “Gene Drives: Dynamics and Regulatory Matters – A Report from the Workshop ‘Evaluation of Spatial and Temporal Control of Gene Drives’, 4 – 5 April 2019, Vienna.” <i>BioEssays</i>. Wiley, 2019. <a href=\"https://doi.org/10.1002/bies.201900151\">https://doi.org/10.1002/bies.201900151</a>.","mla":"Giese, B., et al. “Gene Drives: Dynamics and Regulatory Matters – A Report from the Workshop ‘Evaluation of Spatial and Temporal Control of Gene Drives’, 4 – 5 April 2019, Vienna.” <i>BioEssays</i>, vol. 41, no. 11, 1900151, Wiley, 2019, doi:<a href=\"https://doi.org/10.1002/bies.201900151\">10.1002/bies.201900151</a>.","short":"B. Giese, J.L. Friess, M.F. Schetelig, N.H. Barton, P. Messer, F. Debarre, H. Meimberg, N. Windbichler, C. Boete, BioEssays 41 (2019).","apa":"Giese, B., Friess, J. L., Schetelig, M. F., Barton, N. H., Messer, P., Debarre, F., … Boete, C. (2019). Gene Drives: Dynamics and regulatory matters – A report from the workshop “Evaluation of spatial and temporal control of Gene Drives”, 4 – 5 April 2019, Vienna. <i>BioEssays</i>. Wiley. <a href=\"https://doi.org/10.1002/bies.201900151\">https://doi.org/10.1002/bies.201900151</a>","ista":"Giese B, Friess JL, Schetelig MF, Barton NH, Messer P, Debarre F, Meimberg H, Windbichler N, Boete C. 2019. Gene Drives: Dynamics and regulatory matters – A report from the workshop “Evaluation of spatial and temporal control of Gene Drives”, 4 – 5 April 2019, Vienna. BioEssays. 41(11), 1900151.","ama":"Giese B, Friess JL, Schetelig MF, et al. Gene Drives: Dynamics and regulatory matters – A report from the workshop “Evaluation of spatial and temporal control of Gene Drives”, 4 – 5 April 2019, Vienna. <i>BioEssays</i>. 2019;41(11). doi:<a href=\"https://doi.org/10.1002/bies.201900151\">10.1002/bies.201900151</a>","ieee":"B. Giese <i>et al.</i>, “Gene Drives: Dynamics and regulatory matters – A report from the workshop ‘Evaluation of spatial and temporal control of Gene Drives’, 4 – 5 April 2019, Vienna,” <i>BioEssays</i>, vol. 41, no. 11. Wiley, 2019."},"title":"Gene Drives: Dynamics and regulatory matters – A report from the workshop “Evaluation of spatial and temporal control of Gene Drives”, 4 – 5 April 2019, Vienna","article_type":"original","language":[{"iso":"eng"}],"intvolume":"        41","month":"11","external_id":{"isi":["000489502000001"]},"publication_status":"published","_id":"6857","oa_version":"Published Version","file_date_updated":"2020-07-14T12:47:42Z","status":"public","article_processing_charge":"No","author":[{"full_name":"Giese, B","first_name":"B","last_name":"Giese"},{"full_name":"Friess, J L","first_name":"J L","last_name":"Friess"},{"full_name":"Schetelig, M F ","first_name":"M F ","last_name":"Schetelig"},{"id":"4880FE40-F248-11E8-B48F-1D18A9856A87","last_name":"Barton","full_name":"Barton, Nicholas H","orcid":"0000-0002-8548-5240","first_name":"Nicholas H"},{"last_name":"Messer","full_name":"Messer, Philip","first_name":"Philip"},{"full_name":"Debarre, Florence","first_name":"Florence","last_name":"Debarre"},{"last_name":"Meimberg","first_name":"H","full_name":"Meimberg, H"},{"last_name":"Windbichler","first_name":"N","full_name":"Windbichler, N"},{"last_name":"Boete","first_name":"C","full_name":"Boete, C"}],"quality_controlled":"1","has_accepted_license":"1","date_published":"2019-11-01T00:00:00Z","volume":41,"publication_identifier":{"eissn":["1521-1878"]},"date_created":"2019-09-07T14:40:03Z","tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"type":"journal_article","oa":1,"scopus_import":"1","date_updated":"2023-08-30T06:56:26Z","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","year":"2019"},{"scopus_import":"1","date_updated":"2023-08-29T07:51:09Z","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","year":"2019","oa":1,"volume":6,"publication_identifier":{"issn":["2095-5138"],"eissn":["2053-714X"]},"date_created":"2019-09-07T14:43:02Z","tmp":{"image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"type":"journal_article","has_accepted_license":"1","date_published":"2019-03-01T00:00:00Z","author":[{"id":"4880FE40-F248-11E8-B48F-1D18A9856A87","last_name":"Barton","orcid":"0000-0002-8548-5240","full_name":"Barton, Nicholas H","first_name":"Nicholas H"}],"quality_controlled":"1","article_processing_charge":"No","language":[{"iso":"eng"}],"publication_status":"published","external_id":{"isi":["000467957400025"]},"intvolume":"         6","month":"03","oa_version":"Published Version","_id":"6858","file_date_updated":"2020-10-02T09:16:44Z","status":"public","article_type":"review","citation":{"ista":"Barton NH. 2019. Is speciation driven by cycles of mixing and isolation? National Science Review. 6(2), 291–292.","ieee":"N. H. Barton, “Is speciation driven by cycles of mixing and isolation?,” <i>National Science Review</i>, vol. 6, no. 2. Oxford University Press, pp. 291–292, 2019.","ama":"Barton NH. Is speciation driven by cycles of mixing and isolation? <i>National Science Review</i>. 2019;6(2):291-292. doi:<a href=\"https://doi.org/10.1093/nsr/nwy113\">10.1093/nsr/nwy113</a>","chicago":"Barton, Nicholas H. “Is Speciation Driven by Cycles of Mixing and Isolation?” <i>National Science Review</i>. Oxford University Press, 2019. <a href=\"https://doi.org/10.1093/nsr/nwy113\">https://doi.org/10.1093/nsr/nwy113</a>.","apa":"Barton, N. H. (2019). Is speciation driven by cycles of mixing and isolation? <i>National Science Review</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/nsr/nwy113\">https://doi.org/10.1093/nsr/nwy113</a>","mla":"Barton, Nicholas H. “Is Speciation Driven by Cycles of Mixing and Isolation?” <i>National Science Review</i>, vol. 6, no. 2, Oxford University Press, 2019, pp. 291–92, doi:<a href=\"https://doi.org/10.1093/nsr/nwy113\">10.1093/nsr/nwy113</a>.","short":"N.H. Barton, National Science Review 6 (2019) 291–292."},"title":"Is speciation driven by cycles of mixing and isolation?","day":"01","department":[{"_id":"NiBa"}],"publisher":"Oxford University Press","publication":"National Science Review","doi":"10.1093/nsr/nwy113","isi":1,"page":"291-292","file":[{"success":1,"date_created":"2020-10-02T09:16:44Z","file_name":"2019_NSR_Barton.pdf","date_updated":"2020-10-02T09:16:44Z","file_id":"8595","file_size":106463,"access_level":"open_access","content_type":"application/pdf","creator":"dernst","relation":"main_file","checksum":"571d60fa21a568607d1fd04e119da88c"}],"ddc":["570"],"issue":"2"},{"article_processing_charge":"No","quality_controlled":"1","author":[{"first_name":"Long","full_name":"Zhou, Long","orcid":"0000-0002-1864-8951","last_name":"Zhou","id":"3E751364-F248-11E8-B48F-1D18A9856A87"},{"id":"338D39FE-F248-11E8-B48F-1D18A9856A87","last_name":"Sazanov","full_name":"Sazanov, Leonid A","orcid":"0000-0002-0977-7989","first_name":"Leonid A"}],"status":"public","_id":"6859","oa_version":"None","month":"08","publication_status":"published","intvolume":"       365","external_id":{"isi":["000482464000043"],"pmid":["31439765"]},"language":[{"iso":"eng"}],"year":"2019","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","date_updated":"2023-08-29T07:52:02Z","scopus_import":"1","date_published":"2019-08-23T00:00:00Z","acknowledged_ssus":[{"_id":"ScienComp"}],"type":"journal_article","date_created":"2019-09-07T19:04:45Z","publication_identifier":{"issn":["0036-8075"],"eissn":["1095-9203"]},"volume":365,"abstract":[{"text":"V (vacuolar)/A (archaeal)-type adenosine triphosphatases (ATPases), found in archaeaand eubacteria, couple ATP hydrolysis or synthesis to proton translocation across theplasma membrane using the rotary-catalysis mechanism. They belong to the V-typeATPase family, which differs from the mitochondrial/chloroplast F-type ATP synthasesin overall architecture. We solved cryo–electron microscopy structures of the intactThermus thermophilusV/A-ATPase, reconstituted into lipid nanodiscs, in three rotationalstates and two substates. These structures indicate substantial flexibility betweenV1and Voin a working enzyme, which results from mechanical competition between centralshaft rotation and resistance from the peripheral stalks. We also describedetails of adenosine diphosphate inhibition release, V1-Votorque transmission, andproton translocation, which are relevant for the entire V-type ATPase family.","lang":"eng"}],"pmid":1,"issue":"6455","article_number":"eaaw9144","publication":"Science","publisher":"AAAS","department":[{"_id":"LeSa"}],"day":"23","title":"Structure and conformational plasticity of the intact Thermus thermophilus V/A-type ATPase","related_material":{"link":[{"relation":"press_release","description":"News on IST Website","url":"https://ist.ac.at/en/news/structure-of-protein-nano-turbine-revealed/"}]},"citation":{"ista":"Zhou L, Sazanov LA. 2019. Structure and conformational plasticity of the intact Thermus thermophilus V/A-type ATPase. Science. 365(6455), eaaw9144.","ama":"Zhou L, Sazanov LA. Structure and conformational plasticity of the intact Thermus thermophilus V/A-type ATPase. <i>Science</i>. 2019;365(6455). doi:<a href=\"https://doi.org/10.1126/science.aaw9144\">10.1126/science.aaw9144</a>","ieee":"L. Zhou and L. A. Sazanov, “Structure and conformational plasticity of the intact Thermus thermophilus V/A-type ATPase,” <i>Science</i>, vol. 365, no. 6455. AAAS, 2019.","chicago":"Zhou, Long, and Leonid A Sazanov. “Structure and Conformational Plasticity of the Intact Thermus Thermophilus V/A-Type ATPase.” <i>Science</i>. AAAS, 2019. <a href=\"https://doi.org/10.1126/science.aaw9144\">https://doi.org/10.1126/science.aaw9144</a>.","short":"L. Zhou, L.A. Sazanov, Science 365 (2019).","mla":"Zhou, Long, and Leonid A. Sazanov. “Structure and Conformational Plasticity of the Intact Thermus Thermophilus V/A-Type ATPase.” <i>Science</i>, vol. 365, no. 6455, eaaw9144, AAAS, 2019, doi:<a href=\"https://doi.org/10.1126/science.aaw9144\">10.1126/science.aaw9144</a>.","apa":"Zhou, L., &#38; Sazanov, L. A. (2019). Structure and conformational plasticity of the intact Thermus thermophilus V/A-type ATPase. <i>Science</i>. AAAS. <a href=\"https://doi.org/10.1126/science.aaw9144\">https://doi.org/10.1126/science.aaw9144</a>"},"isi":1,"doi":"10.1126/science.aaw9144"}]