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However, the developmental principles directing the generation of SC cell-type diversity are not understood. Here, we pursued systematic cell lineage tracing in silico and in vivo, preserving full spatial information, using genetic mosaic analysis with double markers (MADM)-based clonal analysis with single-cell sequencing (MADM-CloneSeq). The analysis of clonally related cell lineages revealed that radial glial progenitors (RGPs) in SC are exceptionally multipotent. Individual resident RGPs have the capacity to produce all excitatory and inhibitory SC neuron types, even at the stage of terminal division. While individual clonal units show no pre-defined cellular composition, the establishment of appropriate relative proportions of distinct neuronal types occurs in a PTEN-dependent manner. Collectively, our findings provide an inaugural framework at the single-RGP/-cell level of the mammalian SC ontogeny.","lang":"eng"}],"file":[{"creator":"dernst","file_id":"14944","content_type":"application/pdf","checksum":"32b3788f7085cf44a84108d8faaff3ce","success":1,"access_level":"open_access","file_name":"2024_Neuron_Cheung.pdf","date_created":"2024-02-06T13:56:15Z","relation":"main_file","date_updated":"2024-02-06T13:56:15Z","file_size":5942467}],"date_created":"2023-04-27T09:41:48Z","_id":"12875","scopus_import":"1","doi":"10.1016/j.neuron.2023.11.009","acknowledgement":"We thank Liqun Luo for his continued support, for providing essential resources for generating Fzd10-CreER mice which were generated in his laboratory, and for comments on the manuscript; W. Zhong for providing Nestin-Cre transgenic mouse line for this study; A. Heger for mouse colony management; R. Beattie and T. Asenov for designing and producing components of acute slice recovery chamber for MADM-CloneSeq experiments; and K. Leopold, J. Rodarte and N. Amberg for initial experiments, technical support and/or assistance. This study was supported by the Scientific Service Units (SSU) of IST Austria through resources provided by the Imaging & Optics Facility (IOF), Laboratory Support Facility (LSF), Miba Machine Shop, and Pre-clinical Facility (PCF). G.C. received funding from European Commission (IST plus postdoctoral fellowship). This work was supported by ISTA institutional\r\nfunds; the Austrian Science Fund Special Research Programmes (FWF SFB F78 Neuro Stem Modulation) to S.H. ","publication_identifier":{"eisbn":["1234995621"],"issn":["0896-6273"],"issnl":["1234-5678"]},"article_type":"comment","title":"Multipotent progenitors instruct ontogeny of the superior colliculus","publication_status":"published","oa_version":"Published Version","article_processing_charge":"Yes (via OA deal)","file_date_updated":"2024-02-06T13:56:15Z","ddc":["570"],"language":[{"iso":"eng"}],"month":"01","status":"public","pmid":1,"publisher":"Elsevier","type":"journal_article","external_id":{"pmid":["38096816"]},"date_published":"2024-01-17T00:00:00Z","issue":"2","has_accepted_license":"1","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"project":[{"_id":"059F6AB4-7A3F-11EA-A408-12923DDC885E","name":"Molecular Mechanisms of Neural Stem Cell Lineage Progression","grant_number":"F07805"}],"page":"230-246.e11","day":"17","quality_controlled":"1"},{"day":"02","quality_controlled":"1","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"has_accepted_license":"1","project":[{"name":"TOPOLOGICALLY PROTECTED AND SCALABLE QUANTUM BITS","_id":"237E5020-32DE-11EA-91FC-C7463DDC885E","grant_number":"862046","call_identifier":"H2020"},{"name":"Integrated GermaNIum quanTum tEchnology","_id":"34c0acea-11ca-11ed-8bc3-8775e10fd452","grant_number":"101069515"},{"name":"Quantum bits with Kitaev Transmons","_id":"bdc2ca30-d553-11ed-ba76-cf164a5bb811","grant_number":"101115315"},{"_id":"237B3DA4-32DE-11EA-91FC-C7463DDC885E","name":"Towards scalable hut wire quantum devices","grant_number":"P32235","call_identifier":"FWF"},{"name":"Merging spin and superconducting qubits in planar Ge","_id":"bd8bd29e-d553-11ed-ba76-f0070d4b237a","grant_number":"P36507"},{"_id":"34a66131-11ca-11ed-8bc3-a31681c6b03e","name":"Conventional and unconventional topological superconductors","grant_number":"F8606"}],"publisher":"Springer Nature","pmid":1,"external_id":{"pmid":["38167818"],"oaworkID":["w4390499170"]},"date_published":"2024-01-02T00:00:00Z","type":"journal_article","language":[{"iso":"eng"}],"ddc":["530"],"month":"01","status":"public","doi":"10.1038/s41467-023-44114-0","scopus_import":"1","article_type":"original","acknowledgement":"We acknowledge Alexander Brinkmann, Alessandro Crippa, Francesco Giazotto, Andrew Higginbotham, Andrea Iorio, Giordano Scappucci, Christian Schonenberger, and Lukas Splitthoff for helpful discussions. We thank Marcel Verheijen for the support in the TEM analysis. This research and related results were made possible with the support of the NOMIS\r\nFoundation. It was supported by the Scientific Service Units of ISTA through resources provided by the MIBA Machine Shop and the nanofabrication facility, the European Union’s Horizon 2020 research andinnovation programme under Grant Agreement No 862046, the HORIZONRIA\r\n101069515 project, the European Innovation Council Pathfinder grant no. 101115315 (QuKiT), and the FWF Projects #P-32235, #P-36507 and #F-8606. For the purpose of open access, the authors have applied a CC BY public copyright licence to any Author Accepted Manuscript version arising from this submission. R.S.S. acknowledges Spanish CM “Talento Program\"\r\nProject No. 2022-T1/IND-24070. J.J. acknowledges European Research Council TOCINA 834290.","publication_identifier":{"eissn":["2041-1723"]},"dataavailabilitystatement":"All experimental data included in this work are available at https://zenodo.org/records/10119346.","title":"Parity-conserving Cooper-pair transport and ideal superconducting diode in planar germanium","publication_status":"published","file_date_updated":"2024-01-17T11:03:00Z","article_processing_charge":"Yes","APC_amount":"12345","oa_version":"Published Version","article_number":"169","year":"2024","citation":{"ama":"Valentini M, Sagi O, Baghumyan L, et al. Parity-conserving Cooper-pair transport and ideal superconducting diode in planar germanium. <i>Nature Communications</i>. 2024;15. doi:<a href=\"https://doi.org/10.1038/s41467-023-44114-0\">10.1038/s41467-023-44114-0</a>","ista":"Valentini M, Sagi O, Baghumyan L, de Gijsel T, Jung J, Calcaterra S, Ballabio A, Aguilera Servin JL, Aggarwal K, Janik M, Adletzberger T, Seoane Souto R, Leijnse M, Danon J, Schrade C, Bakkers E, Chrastina D, Isella G, Katsaros G. 2024. Parity-conserving Cooper-pair transport and ideal superconducting diode in planar germanium. Nature Communications. 15, 169.","ieee":"M. Valentini <i>et al.</i>, “Parity-conserving Cooper-pair transport and ideal superconducting diode in planar germanium,” <i>Nature Communications</i>, vol. 15. Springer Nature, 2024.","apa":"Valentini, M., Sagi, O., Baghumyan, L., de Gijsel, T., Jung, J., Calcaterra, S., … Katsaros, G. (2024). Parity-conserving Cooper-pair transport and ideal superconducting diode in planar germanium. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-023-44114-0\">https://doi.org/10.1038/s41467-023-44114-0</a>","chicago":"Valentini, Marco, Oliver Sagi, Levon Baghumyan, Thijs de Gijsel, Jason Jung, Stefano Calcaterra, Andrea Ballabio, et al. “Parity-Conserving Cooper-Pair Transport and Ideal Superconducting Diode in Planar Germanium.” <i>Nature Communications</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1038/s41467-023-44114-0\">https://doi.org/10.1038/s41467-023-44114-0</a>.","short":"M. Valentini, O. Sagi, L. Baghumyan, T. de Gijsel, J. Jung, S. Calcaterra, A. Ballabio, J.L. Aguilera Servin, K. Aggarwal, M. Janik, T. Adletzberger, R. Seoane Souto, M. Leijnse, J. Danon, C. Schrade, E. Bakkers, D. Chrastina, G. Isella, G. Katsaros, Nature Communications 15 (2024).","mla":"Valentini, Marco, et al. “Parity-Conserving Cooper-Pair Transport and Ideal Superconducting Diode in Planar Germanium.” <i>Nature Communications</i>, vol. 15, 169, Springer Nature, 2024, doi:<a href=\"https://doi.org/10.1038/s41467-023-44114-0\">10.1038/s41467-023-44114-0</a>."},"abstract":[{"text":"Superconductor/semiconductor hybrid devices have attracted increasing interest in the past years. Superconducting electronics aims to complement semiconductor technology, while hybrid architectures are at the forefront of new ideas such as topological superconductivity and protected qubits. In this work, we engineer the induced superconductivity in two-dimensional germanium hole gas by varying the distance between the quantum well and the aluminum. We demonstrate a hard superconducting gap and realize an electrically and flux tunable superconducting diode using a superconducting quantum interference device (SQUID). This allows to tune the current phase relation (CPR), to a regime where single Cooper pair tunneling is suppressed, creating a sin(2y) CPR. Shapiro experiments complement this interpretation and the microwave drive allows to create a diode with ≈ 100% efficiency. The reported results open up the path towards integration of spin qubit devices, microwave resonators and (protected) superconducting qubits on  the same silicon technology compatible platform.","lang":"eng"}],"researchdata_availability":"yes","_id":"14793","date_created":"2024-01-14T23:00:56Z","file":[{"access_level":"open_access","success":1,"file_name":"2024_NatureComm_Valentini.pdf","date_created":"2024-01-17T11:03:00Z","date_updated":"2024-01-17T11:03:00Z","file_size":2336595,"relation":"main_file","content_type":"application/pdf","file_id":"14825","creator":"dernst","checksum":"ef79173b45eeaf984ffa61ef2f8a52ab"}],"author":[{"first_name":"Marco","last_name":"Valentini","id":"C0BB2FAC-D767-11E9-B658-BC13E6697425","full_name":"Valentini, Marco"},{"first_name":"Oliver","last_name":"Sagi","id":"71616374-A8E9-11E9-A7CA-09ECE5697425","full_name":"Sagi, Oliver"},{"last_name":"Baghumyan","first_name":"Levon","full_name":"Baghumyan, Levon","id":"7aa1f788-b527-11ee-aa9e-e6111a79e0c7"},{"first_name":"Thijs","last_name":"de Gijsel","id":"a0ece13c-b527-11ee-929d-bad130106eee","full_name":"de Gijsel, Thijs"},{"first_name":"Jason","last_name":"Jung","id":"4C9ACE7A-F248-11E8-B48F-1D18A9856A87","full_name":"Jung, Jason"},{"last_name":"Calcaterra","first_name":"Stefano","full_name":"Calcaterra, Stefano"},{"last_name":"Ballabio","first_name":"Andrea","full_name":"Ballabio, Andrea"},{"full_name":"Aguilera Servin, Juan L","id":"2A67C376-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-2862-8372","last_name":"Aguilera Servin","first_name":"Juan L"},{"orcid":"0000-0001-9985-9293","id":"b22ab905-3539-11eb-84c3-fc159dcd79cb","full_name":"Aggarwal, Kushagra","first_name":"Kushagra","last_name":"Aggarwal"},{"id":"396A1950-F248-11E8-B48F-1D18A9856A87","full_name":"Janik, Marian","first_name":"Marian","last_name":"Janik"},{"last_name":"Adletzberger","first_name":"Thomas","full_name":"Adletzberger, Thomas","id":"38756BB2-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Seoane Souto, Rubén","first_name":"Rubén","last_name":"Seoane Souto"},{"full_name":"Leijnse, Martin","first_name":"Martin","last_name":"Leijnse"},{"first_name":"Jeroen","last_name":"Danon","full_name":"Danon, Jeroen"},{"first_name":"Constantin","last_name":"Schrade","full_name":"Schrade, Constantin"},{"last_name":"Bakkers","first_name":"Erik","full_name":"Bakkers, Erik"},{"full_name":"Chrastina, Daniel","last_name":"Chrastina","first_name":"Daniel"},{"first_name":"Giovanni","last_name":"Isella","full_name":"Isella, Giovanni"},{"last_name":"Katsaros","first_name":"Georgios","full_name":"Katsaros, Georgios","id":"38DB5788-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8342-202X"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","acknowledged_ssus":[{"_id":"M-Shop"},{"_id":"NanoFab"}],"oa":1,"volume":15,"intvolume":"        15","supplementarymaterial":"yes","department":[{"_id":"GeKa"}],"publication":"Nature Communications","ec_funded":1,"date_updated":"2026-02-26T11:39:00Z"},{"quality_controlled":"1","day":"01","issue":"1","project":[{"grant_number":"24812","_id":"2625A13E-B435-11E9-9278-68D0E5697425","name":"Molecular Mechanisms of Radial Neuronal Migration"}],"type":"journal_article","date_published":"2024-01-01T00:00:00Z","external_id":{"pmid":["38165800"],"oaworkID":["34426698 "]},"pmid":1,"publisher":"Elsevier","month":"01","status":"public","language":[{"iso":"eng"}],"publication_status":"epub_ahead","title":"Time-lapse imaging of cortical projection neuron migration in mice using mosaic analysis with double markers","oa_version":"Published Version","article_processing_charge":"Yes","scopus_import":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1016/j.xpro.2023.102795"}],"doi":"10.1016/j.xpro.2023.102795","acknowledgement":"We thank Florian Pauler for discussion and his expert technical support. This research was supported by the Scientific Service Units (SSU) at IST Austria through resources provided by the Imaging and Optics Facility (IOF) and Preclinical Facility (PCF). A.H.H. was a recipient of a DOC Fellowship (24812) of the Austrian Academy of Sciences.","publication_identifier":{"eissn":["2666-1667"]},"article_type":"review","date_created":"2024-01-14T23:00:56Z","_id":"14794","citation":{"short":"A.H. Hansen, S. Hippenmeyer, STAR Protocols 5 (2024).","chicago":"Hansen, Andi H, and Simon Hippenmeyer. “Time-Lapse Imaging of Cortical Projection Neuron Migration in Mice Using Mosaic Analysis with Double Markers.” <i>STAR Protocols</i>. Elsevier, 2024. <a href=\"https://doi.org/10.1016/j.xpro.2023.102795\">https://doi.org/10.1016/j.xpro.2023.102795</a>.","apa":"Hansen, A. H., &#38; Hippenmeyer, S. (2024). Time-lapse imaging of cortical projection neuron migration in mice using mosaic analysis with double markers. <i>STAR Protocols</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.xpro.2023.102795\">https://doi.org/10.1016/j.xpro.2023.102795</a>","mla":"Hansen, Andi H., and Simon Hippenmeyer. “Time-Lapse Imaging of Cortical Projection Neuron Migration in Mice Using Mosaic Analysis with Double Markers.” <i>STAR Protocols</i>, vol. 5, no. 1, 102795, Elsevier, 2024, doi:<a href=\"https://doi.org/10.1016/j.xpro.2023.102795\">10.1016/j.xpro.2023.102795</a>.","ama":"Hansen AH, Hippenmeyer S. Time-lapse imaging of cortical projection neuron migration in mice using mosaic analysis with double markers. <i>STAR Protocols</i>. 2024;5(1). doi:<a href=\"https://doi.org/10.1016/j.xpro.2023.102795\">10.1016/j.xpro.2023.102795</a>","ista":"Hansen AH, Hippenmeyer S. 2024. Time-lapse imaging of cortical projection neuron migration in mice using mosaic analysis with double markers. STAR Protocols. 5(1), 102795.","ieee":"A. H. Hansen and S. Hippenmeyer, “Time-lapse imaging of cortical projection neuron migration in mice using mosaic analysis with double markers,” <i>STAR Protocols</i>, vol. 5, no. 1. Elsevier, 2024."},"year":"2024","article_number":"102795","abstract":[{"text":"Mosaic analysis with double markers (MADM) technology enables the sparse labeling of genetically defined neurons. We present a protocol for time-lapse imaging of cortical projection neuron migration in mice using MADM. We describe steps for the isolation, culturing, and 4D imaging of neuronal dynamics in MADM-labeled brain tissue. While this protocol is compatible with other single-cell labeling methods, the MADM approach provides a genetic platform for the functional assessment of cell-autonomous candidate gene function and the relative contribution of non-cell-autonomous effects.\r\n\r\nFor complete details on the use and execution of this protocol, please refer to Hansen et al. (2022),1 Contreras et al. (2021),2 and Amberg and Hippenmeyer (2021).3","lang":"eng"}],"acknowledged_ssus":[{"_id":"Bio"},{"_id":"PreCl"}],"volume":5,"related_material":{"link":[{"relation":"software","url":"http://github.com/hippenmeyerlab"}]},"oa":1,"author":[{"last_name":"Hansen","first_name":"Andi H","full_name":"Hansen, Andi H","id":"38853E16-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Simon","last_name":"Hippenmeyer","orcid":"0000-0003-2279-1061","id":"37B36620-F248-11E8-B48F-1D18A9856A87","full_name":"Hippenmeyer, Simon"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","department":[{"_id":"SiHi"}],"date_updated":"2025-08-11T11:49:30Z","publication":"STAR Protocols","intvolume":"         5"},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","author":[{"last_name":"Arslan","first_name":"Feyza N","full_name":"Arslan, Feyza N","orcid":"0000-0001-5809-9566","id":"49DA7910-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Hannezo, Edouard B","orcid":"0000-0001-6005-1561","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","last_name":"Hannezo","first_name":"Edouard B"},{"full_name":"Merrin, Jack","id":"4515C308-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5145-4609","last_name":"Merrin","first_name":"Jack"},{"id":"462D4284-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-7309-9724","full_name":"Loose, Martin","first_name":"Martin","last_name":"Loose"},{"full_name":"Heisenberg, Carl-Philipp J","orcid":"0000-0002-0912-4566","id":"39427864-F248-11E8-B48F-1D18A9856A87","last_name":"Heisenberg","first_name":"Carl-Philipp J"}],"volume":34,"oa":1,"acknowledged_ssus":[{"_id":"Bio"},{"_id":"PreCl"}],"intvolume":"        34","arxiv":1,"date_updated":"2025-07-22T14:58:27Z","ec_funded":1,"publication":"Current Biology","department":[{"_id":"CaHe"},{"_id":"EdHa"},{"_id":"MaLo"},{"_id":"NanoFab"}],"publication_identifier":{"issn":["0960-9822"],"eissn":["1879-0445"]},"acknowledgement":"We are grateful to Edwin Munro for their feedback and help with the single particle analysis. We thank members of the Heisenberg and Loose labs for their help and feedback on the manuscript, notably Xin Tong for making the PCS2-mCherry-AHPH plasmid. Finally, we thank the Aquatics and Imaging & Optics facilities of ISTA for their continuous support, especially Yann Cesbron for assistance with the laser cutter. This work was supported by an ERC\r\nAdvanced Grant (MECSPEC) to C.-P.H.","article_type":"original","scopus_import":"1","doi":"10.1016/j.cub.2023.11.067","article_processing_charge":"Yes (via OA deal)","oa_version":"Published Version","file_date_updated":"2024-01-16T10:53:31Z","publication_status":"published","title":"Adhesion-induced cortical flows pattern E-cadherin-mediated cell contacts","abstract":[{"lang":"eng","text":"Metazoan development relies on the formation and remodeling of cell-cell contacts. Dynamic reorganization of adhesion receptors and the actomyosin cell cortex in space and time plays a central role in cell-cell contact formation and maturation. Nevertheless, how this process is mechanistically achieved when new contacts are formed remains unclear. Here, by building a biomimetic assay composed of progenitor cells adhering to supported lipid bilayers functionalized with E-cadherin ectodomains, we show that cortical F-actin flows, driven by the depletion of myosin-2 at the cell contact center, mediate the dynamic reorganization of adhesion receptors and cell cortex at the contact. E-cadherin-dependent downregulation of the small GTPase RhoA at the forming contact leads to both a depletion of myosin-2 and a decrease of F-actin at the contact center. At the contact rim, in contrast, myosin-2 becomes enriched by the retraction of bleb-like protrusions, resulting in a cortical tension gradient from the contact rim to its center. This tension gradient, in turn, triggers centrifugal F-actin flows, leading to further accumulation of F-actin at the contact rim and the progressive redistribution of E-cadherin from the contact center to the rim. Eventually, this combination of actomyosin downregulation and flows at the contact determines the characteristic molecular organization, with E-cadherin and F-actin accumulating at the contact rim, where they are needed to mechanically link the contractile cortices of the adhering cells."}],"citation":{"ieee":"F. N. Arslan, E. B. Hannezo, J. Merrin, M. Loose, and C.-P. J. Heisenberg, “Adhesion-induced cortical flows pattern E-cadherin-mediated cell contacts,” <i>Current Biology</i>, vol. 34, no. 1. Elsevier, p. 171–182.e8, 2024.","ista":"Arslan FN, Hannezo EB, Merrin J, Loose M, Heisenberg C-PJ. 2024. Adhesion-induced cortical flows pattern E-cadherin-mediated cell contacts. Current Biology. 34(1), 171–182.e8.","ama":"Arslan FN, Hannezo EB, Merrin J, Loose M, Heisenberg C-PJ. Adhesion-induced cortical flows pattern E-cadherin-mediated cell contacts. <i>Current Biology</i>. 2024;34(1):171-182.e8. doi:<a href=\"https://doi.org/10.1016/j.cub.2023.11.067\">10.1016/j.cub.2023.11.067</a>","short":"F.N. Arslan, E.B. Hannezo, J. Merrin, M. Loose, C.-P.J. Heisenberg, Current Biology 34 (2024) 171–182.e8.","apa":"Arslan, F. N., Hannezo, E. B., Merrin, J., Loose, M., &#38; Heisenberg, C.-P. J. (2024). Adhesion-induced cortical flows pattern E-cadherin-mediated cell contacts. <i>Current Biology</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.cub.2023.11.067\">https://doi.org/10.1016/j.cub.2023.11.067</a>","chicago":"Arslan, Feyza N, Edouard B Hannezo, Jack Merrin, Martin Loose, and Carl-Philipp J Heisenberg. “Adhesion-Induced Cortical Flows Pattern E-Cadherin-Mediated Cell Contacts.” <i>Current Biology</i>. Elsevier, 2024. <a href=\"https://doi.org/10.1016/j.cub.2023.11.067\">https://doi.org/10.1016/j.cub.2023.11.067</a>.","mla":"Arslan, Feyza N., et al. “Adhesion-Induced Cortical Flows Pattern E-Cadherin-Mediated Cell Contacts.” <i>Current Biology</i>, vol. 34, no. 1, Elsevier, 2024, p. 171–182.e8, doi:<a href=\"https://doi.org/10.1016/j.cub.2023.11.067\">10.1016/j.cub.2023.11.067</a>."},"year":"2024","date_created":"2024-01-14T23:00:56Z","file":[{"file_id":"14813","creator":"dernst","content_type":"application/pdf","checksum":"51220b76d72a614208f84bdbfbaf9b72","file_name":"2024_CurrentBiology_Arslan.pdf","access_level":"open_access","success":1,"date_created":"2024-01-16T10:53:31Z","relation":"main_file","date_updated":"2024-01-16T10:53:31Z","file_size":5183861}],"_id":"14795","corr_author":"1","publisher":"Elsevier","type":"journal_article","date_published":"2024-01-08T00:00:00Z","external_id":{"arxiv":["2410.03589"]},"ddc":["570"],"language":[{"iso":"eng"}],"status":"public","month":"01","day":"08","page":"171-182.e8","quality_controlled":"1","project":[{"name":"Interaction and feedback between cell mechanics and fate specification in vertebrate gastrulation","_id":"260F1432-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"742573"}],"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"has_accepted_license":"1","issue":"1"},{"author":[{"id":"fea1b376-906f-11eb-847d-b2c0cf46455b","full_name":"Clozeau, Nicolas","first_name":"Nicolas","last_name":"Clozeau"},{"last_name":"Mattesini","first_name":"Francesco","full_name":"Mattesini, Francesco"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa":1,"arxiv":1,"department":[{"_id":"JuFi"}],"publication":"Probability Theory and Related Fields","date_updated":"2025-08-12T12:22:41Z","ec_funded":1,"doi":"10.1007/s00440-023-01254-0","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1007/s00440-023-01254-0"}],"scopus_import":"1","article_type":"original","publication_identifier":{"eissn":["1432-2064"],"issn":["0178-8051"]},"acknowledgement":"NC has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (Grant agreement No 948819).\r\nFM is supported by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) through the SPP 2265 Random Geometric Systems. FM has been funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany’s Excellence Strategy EXC 2044 -390685587, Mathematics Münster: Dynamics–Geometry–Structure. FM has been funded by the Max Planck Institute for Mathematics in the Sciences.","publication_status":"epub_ahead","title":"Annealed quantitative estimates for the quadratic 2D-discrete random matching problem","article_processing_charge":"Yes (in subscription journal)","oa_version":"Published Version","year":"2024","citation":{"ama":"Clozeau N, Mattesini F. Annealed quantitative estimates for the quadratic 2D-discrete random matching problem. <i>Probability Theory and Related Fields</i>. 2024. doi:<a href=\"https://doi.org/10.1007/s00440-023-01254-0\">10.1007/s00440-023-01254-0</a>","ieee":"N. Clozeau and F. Mattesini, “Annealed quantitative estimates for the quadratic 2D-discrete random matching problem,” <i>Probability Theory and Related Fields</i>. Springer Nature, 2024.","ista":"Clozeau N, Mattesini F. 2024. Annealed quantitative estimates for the quadratic 2D-discrete random matching problem. Probability Theory and Related Fields.","mla":"Clozeau, Nicolas, and Francesco Mattesini. “Annealed Quantitative Estimates for the Quadratic 2D-Discrete Random Matching Problem.” <i>Probability Theory and Related Fields</i>, Springer Nature, 2024, doi:<a href=\"https://doi.org/10.1007/s00440-023-01254-0\">10.1007/s00440-023-01254-0</a>.","chicago":"Clozeau, Nicolas, and Francesco Mattesini. “Annealed Quantitative Estimates for the Quadratic 2D-Discrete Random Matching Problem.” <i>Probability Theory and Related Fields</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1007/s00440-023-01254-0\">https://doi.org/10.1007/s00440-023-01254-0</a>.","apa":"Clozeau, N., &#38; Mattesini, F. (2024). Annealed quantitative estimates for the quadratic 2D-discrete random matching problem. <i>Probability Theory and Related Fields</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00440-023-01254-0\">https://doi.org/10.1007/s00440-023-01254-0</a>","short":"N. Clozeau, F. Mattesini, Probability Theory and Related Fields (2024)."},"abstract":[{"text":"We study a random matching problem on closed compact  2 -dimensional Riemannian manifolds (with respect to the squared Riemannian distance), with samples of random points whose common law is absolutely continuous with respect to the volume measure with strictly positive and bounded density. We show that given two sequences of numbers  n  and  m=m(n)  of points, asymptotically equivalent as  n  goes to infinity, the optimal transport plan between the two empirical measures  μn  and  νm  is quantitatively well-approximated by  (Id,exp(∇hn))#μn  where  hn  solves a linear elliptic PDE obtained by a regularized first-order linearization of the Monge-Ampère equation. This is obtained in the case of samples of correlated random points for which a stretched exponential decay of the  α -mixing coefficient holds and for a class of discrete-time Markov chains having a unique absolutely continuous invariant measure with respect to the volume measure.","lang":"eng"}],"_id":"14797","date_created":"2024-01-14T23:00:57Z","publisher":"Springer Nature","external_id":{"arxiv":["2303.00353"]},"date_published":"2024-01-04T00:00:00Z","type":"journal_article","language":[{"iso":"eng"}],"ddc":["510"],"keyword":["Troll","Norway","Fjell"],"month":"01","status":"public","day":"04","quality_controlled":"1","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"has_accepted_license":"1","project":[{"grant_number":"948819","call_identifier":"H2020","_id":"0aa76401-070f-11eb-9043-b5bb049fa26d","name":"Bridging Scales in Random Materials"}]},{"year":"2024","abstract":[{"lang":"eng","text":"Frequency-stable lasers form the back bone of precision measurements in science and technology. Such lasers typically attain their stability through frequency locking to reference cavities. State-of-the-art locking performances to date had been achieved using frequency modulation based methods, complemented with active drift cancellation systems. We demonstrate an all passive, modulation-free laser-cavity locking technique (squash locking) that utilizes changes in spatial beam ellipticity for error signal generation, and a coherent polarization post-selection for noise resilience. By comparing two identically built proof-of-principle systems, we show a frequency locking instability of 5×10<jats:sup>−7</jats:sup> relative to the cavity linewidth at 10 s averaging. The results surpass the demonstrated performances of methods engineered over the last five decades, potentially enabling an advancement in the precision control of lasers, while creating avenues for bridging the performance gaps between industrial grade lasers with scientific ones due to the afforded simplicity and scalability."}],"file":[{"content_type":"application/pdf","file_id":"14824","creator":"dernst","checksum":"eb99ca7d0fe73e22f121875175546ed7","file_name":"2023_Optica_Diorico.pdf","access_level":"open_access","success":1,"file_size":4558986,"date_updated":"2024-01-17T08:53:16Z","date_created":"2024-01-17T08:53:16Z","relation":"main_file"}],"date_created":"2024-01-15T10:25:38Z","_id":"14802","doi":"10.1364/optica.507451","acknowledgement":"We thank Rishabh Sahu and Sebastian Wald for technical contributions to the experiment. Funding by Institute of Science and Technology Austria.","publication_identifier":{"issn":["2334-2536"]},"article_type":"original","title":"Laser-cavity locking utilizing beam ellipticity: accessing the 10<sup>−7</sup> instability scale relative to cavity linewidth","publication_status":"published","article_processing_charge":"Yes","oa_version":"Published Version","file_date_updated":"2024-01-17T08:53:16Z","arxiv":1,"intvolume":"        11","department":[{"_id":"OnHo"}],"date_updated":"2024-08-19T09:52:20Z","publication":"Optica","author":[{"orcid":"0000-0002-4947-8924","id":"2E054C4C-F248-11E8-B48F-1D18A9856A87","full_name":"Diorico, Fritz R","first_name":"Fritz R","last_name":"Diorico"},{"first_name":"Artem","last_name":"Zhutov","id":"0f02ed6a-b514-11ee-b891-8379c5f19cb7","full_name":"Zhutov, Artem"},{"full_name":"Hosten, Onur","orcid":"0000-0002-2031-204X","id":"4C02D85E-F248-11E8-B48F-1D18A9856A87","last_name":"Hosten","first_name":"Onur"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","volume":11,"oa":1,"issue":"1","has_accepted_license":"1","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)"},"page":"26-31","day":"20","quality_controlled":"1","ddc":["530"],"language":[{"iso":"eng"}],"keyword":["Atomic and Molecular Physics","and Optics","Electronic","Optical and Magnetic Materials"],"month":"01","status":"public","publisher":"Optica Publishing Group","type":"journal_article","date_published":"2024-01-20T00:00:00Z","external_id":{"arxiv":["2202.13212"]}},{"degree_awarded":"PhD","department":[{"_id":"GradSch"},{"_id":"JoCs"}],"date_updated":"2024-02-01T09:50:29Z","ec_funded":1,"author":[{"first_name":"Heloisa","last_name":"Chiossi","id":"2BBA502C-F248-11E8-B48F-1D18A9856A87","full_name":"Chiossi, Heloisa"}],"user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","year":"2024","citation":{"apa":"Chiossi, H. S. C. (2024). <i>Adaptive hierarchical representations in the hippocampus</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:14821\">https://doi.org/10.15479/at:ista:14821</a>","short":"H.S.C. Chiossi, Adaptive Hierarchical Representations in the Hippocampus, Institute of Science and Technology Austria, 2024.","chicago":"Chiossi, Heloisa S. C. “Adaptive Hierarchical Representations in the Hippocampus.” Institute of Science and Technology Austria, 2024. <a href=\"https://doi.org/10.15479/at:ista:14821\">https://doi.org/10.15479/at:ista:14821</a>.","mla":"Chiossi, Heloisa S. C. <i>Adaptive Hierarchical Representations in the Hippocampus</i>. Institute of Science and Technology Austria, 2024, doi:<a href=\"https://doi.org/10.15479/at:ista:14821\">10.15479/at:ista:14821</a>.","ama":"Chiossi HSC. Adaptive hierarchical representations in the hippocampus. 2024. doi:<a href=\"https://doi.org/10.15479/at:ista:14821\">10.15479/at:ista:14821</a>","ieee":"H. S. C. Chiossi, “Adaptive hierarchical representations in the hippocampus,” Institute of Science and Technology Austria, 2024.","ista":"Chiossi HSC. 2024. Adaptive hierarchical representations in the hippocampus. Institute of Science and Technology Austria."},"supervisor":[{"full_name":"Csicsvari, Jozsef L","id":"3FA14672-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-5193-4036","last_name":"Csicsvari","first_name":"Jozsef L"}],"_id":"14821","file":[{"relation":"source_file","date_created":"2024-01-19T11:04:05Z","file_size":8656268,"date_updated":"2024-01-19T11:04:05Z","access_level":"closed","file_name":"PhD_Thesis_190124.docx","checksum":"d3fa3de1abd5af5204c13e9d55375615","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","creator":"hchiossi","file_id":"14838"},{"file_id":"14839","creator":"hchiossi","content_type":"application/pdf","checksum":"13adc8dcfb5b6b18107f89f0a98fa8bd","access_level":"closed","file_name":"PhD_Thesis_190124.pdf","embargo_to":"open_access","file_size":6567275,"relation":"main_file","date_created":"2024-01-19T11:03:59Z","date_updated":"2024-01-19T11:03:59Z","embargo":"2025-01-19"}],"date_created":"2024-01-16T14:25:21Z","doi":"10.15479/at:ista:14821","publication_identifier":{"issn":["2663 - 337X"]},"publication_status":"published","title":"Adaptive hierarchical representations in the hippocampus","file_date_updated":"2024-01-19T11:04:05Z","article_processing_charge":"No","oa_version":"Published Version","language":[{"iso":"eng"}],"ddc":["570"],"alternative_title":["ISTA Thesis"],"month":"01","status":"public","publisher":"Institute of Science and Technology Austria","date_published":"2024-01-19T00:00:00Z","type":"dissertation","has_accepted_license":"1","project":[{"name":"International IST Doctoral Program","_id":"2564DBCA-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"665385"}],"page":"89","day":"19"}]