@article{2926,
  abstract     = {To fight infectious diseases, host immune defenses are employed at multiple levels. Sanitary behavior, such as pathogen avoidance and removal, acts as a first line of defense to prevent infection [1] before activation of the physiological immune system. Insect societies have evolved a wide range of collective hygiene measures and intensive health care toward pathogen-exposed group members [2]. One of the most common behaviors is allogrooming, in which nestmates remove infectious particles from the body surfaces of exposed individuals [3]. Here we show that, in invasive garden ants, grooming of fungus-exposed brood is effective beyond the sheer mechanical removal of fungal conidiospores; it also includes chemical disinfection through the application of poison produced by the ants themselves. Formic acid is the main active component of the poison. It inhibits fungal growth of conidiospores remaining on the brood surface after grooming and also those collected in the mouth of the grooming ant. This dual function is achieved by uptake of the poison droplet into the mouth through acidopore self-grooming and subsequent application onto the infectious brood via brood grooming. This extraordinary behavior extends the current understanding of grooming and the establishment of social immunity in insect societies.},
  author       = {Tragust, Simon and Mitteregger, Barbara and Barone, Vanessa and Konrad, Matthias and Ugelvig, Line V and Cremer, Sylvia},
  journal      = {Current Biology},
  number       = {1},
  pages        = {76 -- 82},
  publisher    = {Cell Press},
  title        = {{Ants disinfect fungus-exposed brood by oral uptake and spread of their poison}},
  doi          = {10.1016/j.cub.2012.11.034},
  volume       = {23},
  year         = {2013},
}

@article{2939,
  abstract     = {In this paper, we present the first output-sensitive algorithm to compute the persistence diagram of a filtered simplicial complex. For any Γ > 0, it returns only those homology classes with persistence at least Γ. Instead of the classical reduction via column operations, our algorithm performs rank computations on submatrices of the boundary matrix. For an arbitrary constant δ ∈ (0, 1), the running time is O (C (1 - δ) Γ R d (n) log n), where C (1 - δ) Γ is the number of homology classes with persistence at least (1 - δ) Γ, n is the total number of simplices in the complex, d its dimension, and R d (n) is the complexity of computing the rank of an n × n matrix with O (d n) nonzero entries. Depending on the choice of the rank algorithm, this yields a deterministic O (C (1 - δ) Γ n 2.376) algorithm, an O (C (1 - δ) Γ n 2.28) Las-Vegas algorithm, or an O (C (1 - δ) Γ n 2 + ε{lunate}) Monte-Carlo algorithm for an arbitrary ε{lunate} > 0. The space complexity of the Monte-Carlo version is bounded by O (d n) = O (n log n).},
  author       = {Chen, Chao and Kerber, Michael},
  journal      = {Computational Geometry: Theory and Applications},
  number       = {4},
  pages        = {435 -- 447},
  publisher    = {Elsevier},
  title        = {{An output sensitive algorithm for persistent homology}},
  doi          = {10.1016/j.comgeo.2012.02.010},
  volume       = {46},
  year         = {2013},
}

@inproceedings{2940,
  abstract     = {A chain rule for an entropy notion H(.) states that the entropy H(X) of a variable X decreases by at most l if conditioned on an l-bit string A, i.e., H(X|A)>= H(X)-l. More generally, it satisfies a chain rule for conditional entropy if H(X|Y,A)>= H(X|Y)-l.

All natural information theoretic entropy notions we are aware of (like Shannon or min-entropy) satisfy some kind of chain rule for conditional entropy. Moreover, many computational entropy notions (like Yao entropy, unpredictability entropy and several variants of HILL entropy) satisfy the chain rule for conditional entropy, though here not only the quantity decreases by l, but also the quality of the entropy decreases exponentially in l. However, for 
the standard notion of conditional HILL entropy (the computational equivalent of min-entropy) the existence of such a rule was unknown so far.

In this paper, we prove that for conditional HILL entropy no meaningful chain rule exists, assuming the existence of one-way permutations: there exist distributions X,Y,A, where A is a distribution over a single bit, but  $H(X|Y)>>H(X|Y,A)$, even if we simultaneously allow for a massive degradation in the quality of the entropy.

The idea underlying our construction is based on a surprising connection between the chain rule for HILL entropy and deniable encryption. },
  author       = {Krenn, Stephan and Pietrzak, Krzysztof Z and Wadia, Akshay},
  editor       = {Sahai, Amit},
  location     = {Tokyo, Japan},
  pages        = {23 -- 39},
  publisher    = {Springer},
  title        = {{A counterexample to the chain rule for conditional HILL entropy, and what deniable encryption has to do with it}},
  doi          = {10.1007/978-3-642-36594-2_2},
  volume       = {7785},
  year         = {2013},
}

@article{2944,
  abstract     = {We propose a two-step procedure for estimating multiple migration rates in an approximate Bayesian computation (ABC) framework, accounting for global nuisance parameters. The approach is not limited to migration, but generally of interest for inference problems with multiple parameters and a modular structure (e.g. independent sets of demes or loci). We condition on a known, but complex demographic model of a spatially subdivided population, motivated by the reintroduction of Alpine ibex (Capra ibex) into Switzerland. In the first step, the global parameters ancestral mutation rate and male mating skew have been estimated for the whole population in Aeschbacher et al. (Genetics 2012; 192: 1027). In the second step, we estimate in this study the migration rates independently for clusters of demes putatively connected by migration. For large clusters (many migration rates), ABC faces the problem of too many summary statistics. We therefore assess by simulation if estimation per pair of demes is a valid alternative. We find that the trade-off between reduced dimensionality for the pairwise estimation on the one hand and lower accuracy due to the assumption of pairwise independence on the other depends on the number of migration rates to be inferred: the accuracy of the pairwise approach increases with the number of parameters, relative to the joint estimation approach. To distinguish between low and zero migration, we perform ABC-type model comparison between a model with migration and one without. Applying the approach to microsatellite data from Alpine ibex, we find no evidence for substantial gene flow via migration, except for one pair of demes in one direction.},
  author       = {Aeschbacher, Simon and Futschik, Andreas and Beaumont, Mark},
  journal      = {Molecular Ecology},
  number       = {4},
  pages        = {987 -- 1002},
  publisher    = {Wiley-Blackwell},
  title        = {{Approximate Bayesian computation for modular inference problems with many parameters: the example of migration rates. }},
  doi          = {10.1111/mec.12165},
  volume       = {22},
  year         = {2013},
}

@inproceedings{2948,
  abstract     = {Many visual datasets are traditionally used to analyze the performance of different learning techniques. The evaluation is usually done within each dataset, therefore it is questionable if such results are a reliable indicator of true generalization ability. We propose here an algorithm to exploit the existing data resources when learning on a new multiclass problem. Our main idea is to identify an image representation that decomposes orthogonally into two subspaces: a part specific to each dataset, and a part generic to, and therefore shared between, all the considered source sets. This allows us to use the generic representation as un-biased reference knowledge for a novel classification task. By casting the method in the multi-view setting, we also make it possible to use different features for different databases. We call the algorithm MUST, Multitask Unaligned Shared knowledge Transfer. Through extensive experiments on five public datasets, we show that MUST consistently improves the cross-datasets generalization performance.},
  author       = {Tommasi, Tatiana and Quadrianto, Novi and Caputo, Barbara and Lampert, Christoph},
  location     = {Daejeon, Korea},
  pages        = {1 -- 15},
  publisher    = {Springer},
  title        = {{Beyond dataset bias: Multi-task unaligned shared knowledge transfer}},
  doi          = {10.1007/978-3-642-37331-2_1},
  volume       = {7724},
  year         = {2013},
}

@inproceedings{2973,
  abstract     = {Efficient zero-knowledge proofs of knowledge (ZK-PoK) are basic building blocks of many practical cryptographic applications such as identification schemes, group signatures, and secure multiparty computation. Currently, first applications that critically rely on ZK-PoKs are being deployed in the real world. The most prominent example is Direct Anonymous Attestation (DAA), which was adopted by the Trusted Computing Group (TCG) and implemented as one of the functionalities of the cryptographic Trusted Platform Module (TPM) chip.

Implementing systems using ZK-PoK turns out to be challenging, since ZK-PoK are, loosely speaking, significantly more complex than standard crypto primitives, such as encryption and signature schemes. As a result, implementation cycles of ZK-PoK are time-consuming and error-prone, in particular for developers with minor or no cryptographic skills. 

In this paper we report on our ongoing and future research vision with the goal to bring ZK-PoK to practice by making them accessible to crypto and security engineers. To this end we are developing compilers and related tools that support and partially automate the design, implementation, verification and secure implementation of ZK-PoK protocols.},
  author       = {Bangerter, Endre and Barzan, Stefania and Stephan Krenn and Sadeghi, Ahmad-Reza and Schneider, Thomas and Tsay, Joe-Kai},
  editor       = {Christianson, Bruce and Malcolm, James A. and Matyas, Vashek and Roe, Michael},
  pages        = {51 -- 62},
  publisher    = {Springer},
  title        = {{Bringing Zero-Knowledge Proofs of Knowledge to Practice}},
  doi          = {10.1007/978-3-642-36213-2_9},
  volume       = {7028},
  year         = {2013},
}

@article{3116,
  abstract     = {Multithreaded programs coordinate their interaction through synchronization primitives like mutexes and semaphores, which are managed by an OS-provided resource manager. We propose algorithms for the automatic construction of code-aware resource managers for multithreaded embedded applications. Such managers use knowledge about the structure and resource usage (mutex and semaphore usage) of the threads to guarantee deadlock freedom and progress while managing resources in an efficient way. Our algorithms compute managers as winning strategies in certain infinite games, and produce a compact code description of these strategies. We have implemented the algorithms in the tool Cynthesis. Given a multithreaded program in C, the tool produces C code implementing a code-aware resource manager. We show in experiments that Cynthesis produces compact resource managers within a few minutes on a set of embedded benchmarks with up to 6 threads. © 2012 Springer Science+Business Media, LLC.},
  author       = {Chatterjee, Krishnendu and De Alfaro, Luca and Faella, Marco and Majumdar, Ritankar and Raman, Vishwanath},
  journal      = {Formal Methods in System Design},
  number       = {2},
  pages        = {142 -- 174},
  publisher    = {Springer},
  title        = {{Code aware resource management}},
  doi          = {10.1007/s10703-012-0170-4},
  volume       = {42},
  year         = {2013},
}

@article{3261,
  abstract     = {Cells in a developing embryo have no direct way of "measuring" their physical position. Through a variety of processes, however, the expression levels of multiple genes come to be correlated with position, and these expression levels thus form a code for "positional information." We show how to measure this information, in bits, using the gap genes in the Drosophila embryo as an example. Individual genes carry nearly two bits of information, twice as much as expected if the expression patterns consisted only of on/off domains separated by sharp boundaries. Taken together, four gap genes carry enough information to define a cell's location with an error bar of ~1% along the anterior-posterior axis of the embryo. This precision is nearly enough for each cell to have a unique identity, which is the maximum information the system can use, and is nearly constant along the length of the embryo. We argue that this constancy is a signature of optimality in the transmission of information from primary morphogen inputs to the output of the gap gene network.},
  author       = {Dubuis, Julien and Tkacik, Gasper and Wieschaus, Eric and Gregor, Thomas and Bialek, William},
  journal      = {PNAS},
  number       = {41},
  pages        = {16301 -- 16308},
  publisher    = {National Academy of Sciences},
  title        = {{Positional information, in bits}},
  doi          = {10.1073/pnas.1315642110},
  volume       = {110},
  year         = {2013},
}

@article{331,
  abstract     = {We report a procedure to prepare highly monodisperse copper telluride nanocubes, nanoplates, and nanorods. The procedure is based on the reaction of a copper salt with trioctylphosphine telluride in the presence of lithium bis(trimethylsilyl)amide and oleylamine. CuTe nanocrystals display a strong near-infrared optical absorption associated with localized surface plasmon resonances. We exploit this plasmon resonance for the design of surface-enhanced Raman scattering sensors for unconventional optical probes. Furthermore, we also report here our preliminary analysis of the use of CuTe nanocrystals as cytotoxic and photothermal agents.},
  author       = {Li, Wenhua and Zamani, Reza and Rivera Gil, Pilar and Pelaz, Beatriz and Ibáñez, Maria and Cadavid, Doris and Shavel, Alexey and Alvarez Puebla, Ramon and Parak, Wolfgang and Arbiol, Jordi and Cabot, Andreu},
  journal      = {Journal of the American Chemical Society},
  number       = {19},
  pages        = {7098 -- 7101},
  publisher    = {ACS},
  title        = {{CuTe nanocrystals: Shape and size control, plasmonic properties, and use as SERS probes and photothermal agents}},
  doi          = {10.1021/ja401428e},
  volume       = {135},
  year         = {2013},
}

@misc{3321,
  author       = {Quadrianto, Novi and Lampert, Christoph},
  booktitle    = {Encyclopedia of Systems Biology},
  editor       = {Dubitzky, Werner and Wolkenhauer, Olaf and Cho, Kwang and Yokota, Hiroki},
  pages        = {1069 -- 1069},
  publisher    = {Springer},
  title        = {{Kernel based learning}},
  doi          = {10.1007/978-1-4419-9863-7_604},
  volume       = {3},
  year         = {2013},
}

@article{342,
  abstract     = {Morphology is a key parameter in the design of novel nanocrystals and nanomaterials with controlled functional properties. Here, we demonstrate the potential of foreign metal ions to tune the morphology of colloidal semiconductor nanoparticles. We illustrate the underlying mechanism by preparing copper selenide nanocubes in the presence of Al ions. We further characterize the plasmonic properties of the obtained nanocrystals and demonstrate their potential as a platform to produce cubic nanoparticles with different composition by cation exchange. © 2013 American Chemical Society.},
  author       = {Li, Wenhua and Zamani, Reza and Ibáñez, Maria and Cadavid, Doris and Shavel, Alexey and Morante, Joan and Arbiol, Jordi and Cabot, Andreu},
  journal      = {Journal of the American Chemical Society},
  number       = {12},
  pages        = {4664 -- 4667},
  publisher    = {American Chemical Society},
  title        = {{Metal ions to control the morphology of semiconductor nanoparticles: Copper selenide nanocubes}},
  doi          = {10.1021/ja400472m},
  volume       = {135},
  year         = {2013},
}

@article{343,
  abstract     = {The bottom-up assembly of nanocrystals provides access to a three-dimensional composition control at the nanoscale not attainable by any other technology. In particular, colloidal nanoheterostructures, with intrinsic multiphase organization, are especially appealing building blocks for the bottom-up production of nanocomposites. In the present work, we use PbTe-PbS as the model material system and thermoelectricity as the paradigmatic application to investigate the potential of the bottom-up assembly of core-shell nanoparticles to produce functional nanocomposites. With this goal in mind, a rapid, high-yield and scalable colloidal synthetic route to prepare grams of PbTe@PbS core-shell nanoparticles with unprecedented narrow size distributions and exceptional composition control is detailed. PbTe@PbS nanoparticles were used as building blocks for the bottom-up production of PbTe-PbS nanocomposites with tuned composition. In such PbTe-PbS nanocomposites, synergistic nanocrystal doping effects result in up to 10-fold higher electrical conductivities than in pure PbTe and PbS nanomaterials. At the same time, the acoustic impedance mismatch between PbTe and PbS phases and a partial phase alloying provide PbTe-PbS nanocomposites with strongly reduced thermal conductivities. As a result, record thermoelectric figures of merit (ZT) of ∼1.1 were obtained from undoped PbTe and PbS phases at 710 K. These high ZT values prove the potential of the proposed processes to produce efficient functional nanomaterials with programmable properties. © 2013 American Chemical Society.},
  author       = {Ibáñez, Maria and Zamani, Reza and Gorsse, Stéphane and Fan, Jiandong and Ortega, Silvia and Cadavid, Doris and Morante, Joan and Arbiol, Jordi and Cabot, Andreu},
  journal      = {ACS Nano},
  number       = {3},
  pages        = {2573 -- 2586},
  publisher    = {American Chemical Society},
  title        = {{Core shell nanoparticles as building blocks for the bottom-up production of functional nanocomposites: PbTe PbS thermoelectric properties}},
  doi          = {10.1021/nn305971v},
  volume       = {7},
  year         = {2013},
}

@article{344,
  abstract     = {Copper-based selenides are attracting increasing interest due to their outstanding optoelectronic and thermoelectric properties. Herein a novel colloidal synthetic route to prepare Cu2SnSe3 nanocrystals with controlled size, shape and composition is presented. The high yield of the developed procedure allowed its up-scaling to the production of grams of colloidal Cu2SnSe3 nanocrystals. These nanocrystals were used as building blocks for the production of Cu2SnSe3 bulk nanostructured materials by spark plasma sintering. The thermoelectric properties of the prepared nanocrystalline Cu2SnSe3 pellets were characterized in the temperature range from 300 to 720 K. The obtained results show the bottom-up production of nanocrystalline materials from solution-processed nanocrystals to be a potentially advantageous alternative to conventional methods of production of efficient thermoelectric materials.},
  author       = {Ibáñez, Maria and Cadavid, Doris and Anselmi Tamburini, Umberto and Zamani, Reza and Gorsse, Stéphane and Li, Wenhua and López, Antonio and Morante, Joan and Arbiol, Jordi and Cabot, Andreu},
  journal      = {Journal of Materials Chemistry A},
  number       = {4},
  pages        = {1421 -- 1426},
  publisher    = {Royal Society of Chemistry},
  title        = {{Colloidal synthesis and thermoelectric properties of Cu 2SnSe3 nanocrystals}},
  doi          = {10.1039/C2TA00419D},
  volume       = {1},
  year         = {2013},
}

@article{351,
  abstract     = {A multistrategy approach to overcome the main challenges of nanoparticle-based solution-processed Cu2ZnSnSe4 thin film solar cells is presented. We developed an efficient ligand exchange strategy, using an antimony salt, to displace organic ligands from the surface of Cu 2ZnSnS4 nanoparticles. An automated pulsed spray-deposition system was used to deposit the nanoparticles into homogeneous and crack-free films with controlled thickness. After annealing the film in a Se-rich atmosphere, carbon-free and crystalline Cu2ZnSnSe4 absorber layers were obtained. Not only was crystallization promoted by the complete removal of organics, but also Sb itself played a critical role. The Sb-assisted crystal growth is associated with the formation of a Sb-based compound at the grain boundaries, which locally reduces the melting point, thus promoting the film diffusion-limited crystallization. },
  author       = {Carrete, Alex and Shavel, Alexey and Fontané, Xavier and Montserrat, Joana and Fan, Jiandong and Ibáñez, Maria and Saucedo, Edgardo and Pérez Rodríguez, Alejandro and Cabot, Andreu},
  journal      = {Journal of the American Chemical Society},
  number       = {43},
  pages        = {15982 -- 15985},
  publisher    = {American Chemical Society},
  title        = {{Antimony-based ligand exchange to promote crystallization in spray-deposited Cu2ZnSnSe4 solar cells}},
  doi          = {10.1021/ja4068639},
  volume       = {135},
  year         = {2013},
}

@article{352,
  abstract     = {The presence of organic ligands on the surface of colloidal nanoparticles strongly limits their performance in technological applications where charge carrier transfer/transport plays an important role. We use metal salts, matched with the nanoparticle composition, to eliminate the surface organic ligands without introducing extrinsic impurities in the final nanomaterial. The potential of the simple, general and scalable processes presented here is demonstrated by characterizing the thermoelectric properties of nanostructured Ag2Te produced by the bottom up assembly of Ag2Te nanocrystals. A 6-fold increase of the thermoelectric figure of merit of Ag2Te was obtained when organic ligands were displaced by AgNO3. The same procedure can enhance the performance of nanocrystals and nanocrystal-based devices in a broad range of applications, from photovoltaics and thermoelectrics to catalysis.},
  author       = {Cadavid, Doris and Ibáñez, Maria and Shavel, Alexey and Durá, Oscar and López De La Torre, Marco and Cabot, Andreu},
  journal      = {Journal of Materials Chemistry A},
  number       = {15},
  pages        = {4864 -- 4870},
  publisher    = {Royal Society of Chemistry},
  title        = {{Organic ligand displacement by metal salts to enhance nanoparticle functionality: Thermoelectric properties of Ag inf 2 inf Te}},
  doi          = {10.1039/C3TA01455J},
  volume       = {1},
  year         = {2013},
}

@article{353,
  abstract     = {We report a procedure to prepare highly monodisperse copper telluride nanocubes, nanoplates, and nanorods. The procedure is based on the reaction of a copper salt with trioctylphosphine telluride in the presence of lithium bis(trimethylsilyl)amide and oleylamine. CuTe nanocrystals display a strong near-infrared optical absorption associated with localized surface plasmon resonances. We exploit this plasmon resonance for the design of surface-enhanced Raman scattering sensors for unconventional optical probes. Furthermore, we also report here our preliminary analysis of the use of CuTe nanocrystals as cytotoxic and photothermal agents.},
  author       = {Li, Wenhua and Zamani, Reza and Rivera Gil, Pilar and Pelaz, Beatriz and Ibáñez, Maria and Cadavid, Doris and Shavel, Alexey and Alvarez Puebla, Ramon and Parak, Wolfgang and Arbiol, Jordi and Cabot, Andreu},
  journal      = {Journal of the American Chemical Society},
  number       = {19},
  pages        = {7098 -- 7101},
  publisher    = {American Chemical Society},
  title        = {{CuTe nanocrystals: Shape and size control, plasmonic properties, and use as SERS probes and photothermal agents}},
  doi          = {10.1021/ja401428e},
  volume       = {135},
  year         = {2013},
}

@article{376,
  abstract     = {The compositional versatility of I2–II–IV–VI4 tetrahedrally-coordinated compounds allows for accommodating their functional properties to numerous technological applications. Among them, Cu2ZnSnSe4 is an emerging photovoltaic material and Cu2CdSnSe4 displays excellent thermoelectric properties. The third compound of this family, Cu2HgSnSe4, remains relatively unexplored. Herein, a synthetic route to produce Cu2HgSnSe4 nanoparticles with narrow size distribution and controlled composition is presented. Cu2HgSnSe4 nanoparticles were subsequently used as building blocks to produce bulk nanocrystalline materials, whose thermoelectric properties were analyzed. A very preliminary adjustment of the material composition yielded Seebeck coefficients up to 160 μV K−1, electrical conductivities close to 104 S m−1 and thermal conductivities down to 0.5 W m−1 K−1.},
  author       = {Li, Wenhua and Ibáñez, Maria and Zamani, Reza and García Castelló, Nuria and Stéphane, Grosse and Cadavid, Doris and Prades, Joan and Arbiol, Jordi and Cabot, Andreu},
  journal      = {CrystEngComm},
  pages        = {8966 -- 8971},
  publisher    = {Royal Society of Chemistry},
  title        = {{Cu2HgSnSe4 nanoparticles: synthesis and thermoelectric properties}},
  doi          = {10.1039/C3CE41583J},
  volume       = {44},
  year         = {2013},
}

@article{378,
  abstract     = {Until recently, to prepare nanocrystals of a new material, scientists searched their shelves for the appropriate molecular precursors, surfactants, and solvents. They then optimized the reaction conditions for the atoms to self-assemble into monodisperse nanocrystals (1). This approach is being replaced by a simpler strategy, in which preformed nanocrystals serve as templates to produce nanoparticles with a different composition through chemical transformation. On page 964 of this issue, Oh et al. (2) report a powerful mechanism that allows the composition of oxide nanoparticles to be transformed in solution and at low temperatures.},
  author       = {Ibáñez, Maria and Cabot, Andreu},
  journal      = {Science},
  number       = {6135},
  pages        = {935 -- 936},
  publisher    = {American Association for the Advancement of Science},
  title        = {{All change for nanocrystals}},
  doi          = {10.1126/science.1239221},
  volume       = {340},
  year         = {2013},
}

@article{450,
  abstract     = {Understanding the relative importance of heterosis and outbreeding depression over multiple generations is a key question in evolutionary biology and is essential for identifying appropriate genetic sources for population and ecosystem restoration. Here we use 2455 experimental crosses between 12 population pairs of the rare perennial plant Rutidosis leptorrhynchoides (Asteraceae) to investigate the multi-generational (F1, F2, F3) fitness outcomes of inter-population hybridization. We detected no evidence of outbreeding depression, with inter-population hybrids and backcrosses showing either similar fitness or significant heterosis for fitness components across the three generations. Variation in heterosis among population pairs was best explained by characteristics of the foreign source or home population, and was greatest when the source population was large, with high genetic diversity and low inbreeding, and the home population was small and inbred. Our results indicate that the primary consideration for maximizing progeny fitness following population augmentation or restoration is the use of seed from large, genetically diverse populations.},
  author       = {Pickup, Melinda and Field, David and Rowell, David and Young, Andrew},
  journal      = {Proceedings of the Royal Society of London Series B Biological Sciences},
  number       = {1750},
  publisher    = {Royal Society, The},
  title        = {{Source population characteristics affect heterosis following genetic rescue of fragmented plant populations}},
  doi          = {10.1098/rspb.2012.2058},
  volume       = {280},
  year         = {2013},
}

@article{476,
  abstract     = {Maternal exposure to infection occurring mid-gestation produces a three-fold increase in the risk of schizophrenia in the offspring. The critical initiating factor appears to be the maternal immune activation (MIA) that follows infection. This process can be induced in rodents by exposure of pregnant dams to the viral mimic Poly I:C, which triggers an immune response that results in structural, functional, behavioral, and electrophysiological phenotypes in the adult offspring that model those seen in schizophrenia. We used this model to explore the role of synchronization in brain neural networks, a process thought to be dysfunctional in schizophrenia and previously associated with positive, negative, and cognitive symptoms of schizophrenia. Exposure of pregnant dams to Poly I:C on GD15 produced an impairment in long-range neural synchrony in adult offspring between two regions implicated in schizophrenia pathology; the hippocampus and the medial prefrontal cortex (mPFC). This reduction in synchrony was ameliorated by acute doses of the antipsychotic clozapine. MIA animals have previously been shown to have impaired pre-pulse inhibition (PPI), a gold-standard measure of schizophrenia-like deficits in animal models. Our data showed that deficits in synchrony were positively correlated with the impairments in PPI. Subsequent analysis of LFP activity during the PPI response also showed that reduced coupling between the mPFC and the hippocampus following processing of the pre-pulse was associated with reduced PPI. The ability of the MIA intervention to model neurodevelopmental aspects of schizophrenia pathology provides a useful platform from which to investigate the ontogeny of aberrant synchronous processes. Further, the way in which the model expresses translatable deficits such as aberrant synchrony and reduced PPI will allow researchers to explore novel intervention strategies targeted to these changes. },
  author       = {Dickerson, Desiree and Bilkey, David},
  journal      = {Frontiers in Behavioral Neuroscience},
  number       = {DEC},
  publisher    = {Frontiers Research Foundation},
  title        = {{Aberrant neural synchrony in the maternal immune activation model: Using translatable measures to explore targeted interventions}},
  doi          = {10.3389/fnbeh.2013.00217},
  volume       = {7},
  year         = {2013},
}