[{"extern":"1","month":"07","_id":"6932","date_created":"2019-10-08T12:47:46Z","date_published":"2017-07-01T00:00:00Z","abstract":[{"text":"LCLs or locally checkable labelling problems (e.g. maximal independent set, maximal matching, and vertex colouring) in the LOCAL model of computation are very well-understood in cycles (toroidal 1-dimensional grids): every problem has a complexity of O(1), Θ(log* n), or Θ(n), and the design of optimal algorithms can be fully automated. This work develops the complexity theory of LCL problems for toroidal 2-dimensional grids. The complexity classes are the same as in the 1-dimensional case: O(1), Θ(log* n), and Θ(n). However, given an LCL problem it is undecidable whether its complexity is Θ(log* n) or Θ(n) in 2-dimensional grids.\r\nNevertheless, if we correctly guess that the complexity of a problem is Θ(log* n), we can completely automate the design of optimal algorithms. For any problem we can find an algorithm that is of a normal form A' o Sk, where A' is a finite function, Sk is an algorithm for finding a maximal independent set in kth power of the grid, and k is a constant.\r\nFinally, partially with the help of automated design tools, we classify the complexity of several concrete LCL problems related to colourings and orientations.","lang":"eng"}],"page":"101-110","article_processing_charge":"No","quality_controlled":"1","status":"public","publisher":"ACM Press","publication_status":"published","day":"01","oa_version":"None","year":"2017","type":"conference","author":[{"full_name":"Brandt, Sebastian","first_name":"Sebastian","last_name":"Brandt"},{"last_name":"Hirvonen","full_name":"Hirvonen, Juho","first_name":"Juho"},{"last_name":"Korhonen","full_name":"Korhonen, Janne H.","first_name":"Janne H."},{"first_name":"Tuomo","full_name":"Lempiäinen, Tuomo","last_name":"Lempiäinen"},{"first_name":"Patric R.J.","full_name":"Östergård, Patric R.J.","last_name":"Östergård"},{"last_name":"Purcell","first_name":"Christopher","full_name":"Purcell, Christopher"},{"id":"334EFD2E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6432-6646","last_name":"Rybicki","full_name":"Rybicki, Joel","first_name":"Joel"},{"full_name":"Suomela, Jukka","first_name":"Jukka","last_name":"Suomela"},{"first_name":"Przemysław","full_name":"Uznański, Przemysław","last_name":"Uznański"}],"citation":{"chicago":"Brandt, Sebastian, Juho Hirvonen, Janne H. Korhonen, Tuomo Lempiäinen, Patric R.J. Östergård, Christopher Purcell, Joel Rybicki, Jukka Suomela, and Przemysław Uznański. “LCL Problems on Grids,” 101–10. ACM Press, 2017. <a href=\"https://doi.org/10.1145/3087801.3087833\">https://doi.org/10.1145/3087801.3087833</a>.","ista":"Brandt S, Hirvonen J, Korhonen JH, Lempiäinen T, Östergård PRJ, Purcell C, Rybicki J, Suomela J, Uznański P. 2017. LCL problems on grids. PODC: Principles of Distributed Computing, 101–110.","ieee":"S. Brandt <i>et al.</i>, “LCL problems on grids,” presented at the PODC: Principles of Distributed Computing, Washington, DC, United States, 2017, pp. 101–110.","mla":"Brandt, Sebastian, et al. <i>LCL Problems on Grids</i>. ACM Press, 2017, pp. 101–10, doi:<a href=\"https://doi.org/10.1145/3087801.3087833\">10.1145/3087801.3087833</a>.","short":"S. Brandt, J. Hirvonen, J.H. Korhonen, T. Lempiäinen, P.R.J. Östergård, C. Purcell, J. Rybicki, J. Suomela, P. Uznański, in:, ACM Press, 2017, pp. 101–110.","ama":"Brandt S, Hirvonen J, Korhonen JH, et al. LCL problems on grids. In: ACM Press; 2017:101-110. doi:<a href=\"https://doi.org/10.1145/3087801.3087833\">10.1145/3087801.3087833</a>","apa":"Brandt, S., Hirvonen, J., Korhonen, J. H., Lempiäinen, T., Östergård, P. R. J., Purcell, C., … Uznański, P. (2017). LCL problems on grids (pp. 101–110). Presented at the PODC: Principles of Distributed Computing, Washington, DC, United States: ACM Press. <a href=\"https://doi.org/10.1145/3087801.3087833\">https://doi.org/10.1145/3087801.3087833</a>"},"conference":{"location":"Washington, DC, United States","name":"PODC: Principles of Distributed Computing","end_date":"2017-07-27","start_date":"2017-07-25"},"title":"LCL problems on grids","language":[{"iso":"eng"}],"date_updated":"2021-01-12T08:09:39Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","doi":"10.1145/3087801.3087833","publication_identifier":{"isbn":["9781450349925"]}},{"issue":"13","_id":"694","abstract":[{"lang":"eng","text":"A change regarding the extent of adhesion - hereafter referred to as adhesion plasticity - between adhesive and less-adhesive states of mammalian cells is important for their behavior. To investigate adhesion plasticity, we have selected a stable isogenic subpopulation of human MDA-MB-468 breast carcinoma cells growing in suspension. These suspension cells are unable to re-adhere to various matrices or to contract three-dimensional collagen lattices. By using transcriptome analysis, we identified the focal adhesion protein tensin3 (Tns3) as a determinant of adhesion plasticity. Tns3 is strongly reduced at mRNA and protein levels in suspension cells. Furthermore, by transiently challenging breast cancer cells to grow under non-adherent conditions markedly reduces Tns3 protein expression, which is regained upon re-adhesion. Stable knockdown of Tns3 in parental MDA-MB-468 cells results in defective adhesion, spreading and migration. Tns3-knockdown cells display impaired structure and dynamics of focal adhesion complexes as determined by immunostaining. Restoration of Tns3 protein expression in suspension cells partially rescues adhesion and focal contact composition. Our work identifies Tns3 as a crucial focal adhesion component regulated by, and functionally contributing to, the switch between adhesive and non-adhesive states in MDA-MB-468 cancer cells."}],"date_published":"2017-07-01T00:00:00Z","file":[{"access_level":"open_access","date_updated":"2020-07-14T12:47:45Z","checksum":"42c81a0a4fc3128883b391c3af3f74bc","file_size":10847596,"creator":"dernst","file_name":"2017_CellScience_Vess.pdf","date_created":"2019-10-24T09:43:56Z","relation":"main_file","file_id":"6966","content_type":"application/pdf"}],"oa":1,"publication_status":"published","volume":130,"file_date_updated":"2020-07-14T12:47:45Z","has_accepted_license":"1","year":"2017","oa_version":"Published Version","article_type":"original","publist_id":"7008","publication_identifier":{"issn":["00219533"]},"external_id":{"pmid":["28515231"]},"scopus_import":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2021-01-12T08:09:41Z","page":"2172 - 2184","date_created":"2018-12-11T11:47:58Z","month":"07","publisher":"Company of Biologists","status":"public","intvolume":"       130","publication":"Journal of Cell Science","department":[{"_id":"MiSi"}],"quality_controlled":"1","title":"A dual phenotype of MDA MB 468 cancer cells reveals mutual regulation of tensin3 and adhesion plasticity","citation":{"ama":"Veß A, Blache U, Leitner L, et al. A dual phenotype of MDA MB 468 cancer cells reveals mutual regulation of tensin3 and adhesion plasticity. <i>Journal of Cell Science</i>. 2017;130(13):2172-2184. doi:<a href=\"https://doi.org/10.1242/jcs.200899\">10.1242/jcs.200899</a>","apa":"Veß, A., Blache, U., Leitner, L., Kurz, A., Ehrenpfordt, A., Sixt, M. K., &#38; Posern, G. (2017). A dual phenotype of MDA MB 468 cancer cells reveals mutual regulation of tensin3 and adhesion plasticity. <i>Journal of Cell Science</i>. Company of Biologists. <a href=\"https://doi.org/10.1242/jcs.200899\">https://doi.org/10.1242/jcs.200899</a>","short":"A. Veß, U. Blache, L. Leitner, A. Kurz, A. Ehrenpfordt, M.K. Sixt, G. Posern, Journal of Cell Science 130 (2017) 2172–2184.","mla":"Veß, Astrid, et al. “A Dual Phenotype of MDA MB 468 Cancer Cells Reveals Mutual Regulation of Tensin3 and Adhesion Plasticity.” <i>Journal of Cell Science</i>, vol. 130, no. 13, Company of Biologists, 2017, pp. 2172–84, doi:<a href=\"https://doi.org/10.1242/jcs.200899\">10.1242/jcs.200899</a>.","chicago":"Veß, Astrid, Ulrich Blache, Laura Leitner, Angela Kurz, Anja Ehrenpfordt, Michael K Sixt, and Guido Posern. “A Dual Phenotype of MDA MB 468 Cancer Cells Reveals Mutual Regulation of Tensin3 and Adhesion Plasticity.” <i>Journal of Cell Science</i>. Company of Biologists, 2017. <a href=\"https://doi.org/10.1242/jcs.200899\">https://doi.org/10.1242/jcs.200899</a>.","ieee":"A. Veß <i>et al.</i>, “A dual phenotype of MDA MB 468 cancer cells reveals mutual regulation of tensin3 and adhesion plasticity,” <i>Journal of Cell Science</i>, vol. 130, no. 13. Company of Biologists, pp. 2172–2184, 2017.","ista":"Veß A, Blache U, Leitner L, Kurz A, Ehrenpfordt A, Sixt MK, Posern G. 2017. A dual phenotype of MDA MB 468 cancer cells reveals mutual regulation of tensin3 and adhesion plasticity. Journal of Cell Science. 130(13), 2172–2184."},"author":[{"last_name":"Veß","first_name":"Astrid","full_name":"Veß, Astrid"},{"full_name":"Blache, Ulrich","first_name":"Ulrich","last_name":"Blache"},{"first_name":"Laura","full_name":"Leitner, Laura","last_name":"Leitner"},{"last_name":"Kurz","first_name":"Angela","full_name":"Kurz, Angela"},{"full_name":"Ehrenpfordt, Anja","first_name":"Anja","last_name":"Ehrenpfordt"},{"orcid":"0000-0002-6620-9179","id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87","first_name":"Michael K","full_name":"Sixt, Michael K","last_name":"Sixt"},{"last_name":"Posern","first_name":"Guido","full_name":"Posern, Guido"}],"type":"journal_article","day":"01","pmid":1,"doi":"10.1242/jcs.200899","ddc":["570"],"language":[{"iso":"eng"}]},{"publication_status":"published","publisher":"Elsevier","quality_controlled":"1","publication":"Flora: Morphology, Distribution, Functional Ecology of Plants","volume":232,"status":"public","intvolume":"       232","page":"7 - 15","extern":"1","month":"07","abstract":[{"lang":"eng","text":"It has been known since Stefan Vogel's observations in 1969 that solitary female oil bees collect fatty floral oils from specialized oil-secreting plants with the aid of hairy patches on either their legs or abdomen, a reward used as food for their larvae and/or to line their brood cells. Similar adaptations are also known from male oil bees, although the purpose of their oil-collecting behavior has not yet been clarified. Here, we describe a novel pollination system involving male Paratetrapedia oil bees and the tropical herb Anthurium acutifolium. We present ultrastructural morphological details of bee and plant structures involved in this interaction and the composition of floral scents likely mediating pollinator attraction. Inflorescences of A. acutifolium were visited almost exclusively by male P. chocoensis oil bees. The bees mopped with a hairy patch of their abdominal sterna 3 across the inflorescence surface. During this activity on both staminate and pistillate stage inflorescences, bees’ abdomens and legs became loaded with pollen and contacted receptive stigmas. In contrast to what has been observed in other angiosperms visited for the collection of fatty floral oils, the inflorescences/flowers of A. acutifolium do not have structures specialized in oil secretion, i.e., elaiophores. These inflorescences, nonetheless, were strongly scented during the time interval they were visited by the bees. Gas chromatography/mass spectrometry (GC/MS) analyses of dynamic headspace floral samples revealed that inflorescences of both anthetic phases emitted scent bouquets consisting mainly of aliphatic esters, indole and uncommmon terpenoids (megastigmanes). Interestingly enough, our data suggest that the unusual floral scent of A. acutifolium is a perfume reward collected by male P. chocoensis oil bees. This pollination system thus bears a remarkable resemblence with the interactions between perfume-collecting male euglossine bees and their preferred flowers, discovered by Stefan Vogel half a century ago."}],"_id":"695","date_published":"2017-07-01T00:00:00Z","date_created":"2018-12-11T11:47:58Z","language":[{"iso":"eng"}],"user_id":"4435EBFC-F248-11E8-B48F-1D18A9856A87","date_updated":"2021-01-12T08:09:44Z","doi":"10.1016/j.flora.2017.02.020","publication_identifier":{"issn":["03672530"]},"citation":{"mla":"Etl, Florian, et al. “A Perfume Collecting Male Oil Bee? Evidences of a Novel Pollination System Involving Anthurium Acutifolium Araceae and Paratetrapedia Chocoensis Apidae Tapinotaspidini.” <i>Flora: Morphology, Distribution, Functional Ecology of Plants</i>, vol. 232, Elsevier, 2017, pp. 7–15, doi:<a href=\"https://doi.org/10.1016/j.flora.2017.02.020\">10.1016/j.flora.2017.02.020</a>.","ieee":"F. Etl, A. Franschitz, A. Aguiar, J. Schönenberger, and S. Dötterl, “A perfume collecting male oil bee? Evidences of a novel pollination system involving Anthurium acutifolium Araceae and Paratetrapedia chocoensis Apidae Tapinotaspidini,” <i>Flora: Morphology, Distribution, Functional Ecology of Plants</i>, vol. 232. Elsevier, pp. 7–15, 2017.","ista":"Etl F, Franschitz A, Aguiar A, Schönenberger J, Dötterl S. 2017. A perfume collecting male oil bee? Evidences of a novel pollination system involving Anthurium acutifolium Araceae and Paratetrapedia chocoensis Apidae Tapinotaspidini. Flora: Morphology, Distribution, Functional Ecology of Plants. 232, 7–15.","chicago":"Etl, Florian, Anna Franschitz, Antonio Aguiar, Jürg Schönenberger, and Stefan Dötterl. “A Perfume Collecting Male Oil Bee? Evidences of a Novel Pollination System Involving Anthurium Acutifolium Araceae and Paratetrapedia Chocoensis Apidae Tapinotaspidini.” <i>Flora: Morphology, Distribution, Functional Ecology of Plants</i>. Elsevier, 2017. <a href=\"https://doi.org/10.1016/j.flora.2017.02.020\">https://doi.org/10.1016/j.flora.2017.02.020</a>.","apa":"Etl, F., Franschitz, A., Aguiar, A., Schönenberger, J., &#38; Dötterl, S. (2017). A perfume collecting male oil bee? Evidences of a novel pollination system involving Anthurium acutifolium Araceae and Paratetrapedia chocoensis Apidae Tapinotaspidini. <i>Flora: Morphology, Distribution, Functional Ecology of Plants</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.flora.2017.02.020\">https://doi.org/10.1016/j.flora.2017.02.020</a>","ama":"Etl F, Franschitz A, Aguiar A, Schönenberger J, Dötterl S. A perfume collecting male oil bee? Evidences of a novel pollination system involving Anthurium acutifolium Araceae and Paratetrapedia chocoensis Apidae Tapinotaspidini. <i>Flora: Morphology, Distribution, Functional Ecology of Plants</i>. 2017;232:7-15. doi:<a href=\"https://doi.org/10.1016/j.flora.2017.02.020\">10.1016/j.flora.2017.02.020</a>","short":"F. Etl, A. Franschitz, A. Aguiar, J. Schönenberger, S. Dötterl, Flora: Morphology, Distribution, Functional Ecology of Plants 232 (2017) 7–15."},"title":"A perfume collecting male oil bee? Evidences of a novel pollination system involving Anthurium acutifolium Araceae and Paratetrapedia chocoensis Apidae Tapinotaspidini","publist_id":"7007","day":"01","year":"2017","oa_version":"None","type":"journal_article","author":[{"last_name":"Etl","full_name":"Etl, Florian","first_name":"Florian"},{"last_name":"Franschitz","full_name":"Franschitz, Anna","first_name":"Anna","id":"480826C8-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Antonio","full_name":"Aguiar, Antonio","last_name":"Aguiar"},{"last_name":"Schönenberger","first_name":"Jürg","full_name":"Schönenberger, Jürg"},{"last_name":"Dötterl","full_name":"Dötterl, Stefan","first_name":"Stefan"}]},{"language":[{"iso":"eng"}],"doi":"10.1371/journal.pcbi.1005609","ddc":["576"],"project":[{"call_identifier":"FP7","_id":"25B1EC9E-B435-11E9-9278-68D0E5697425","grant_number":"618091","name":"Speed of Adaptation in Population Genetics and Evolutionary Computation"}],"related_material":{"record":[{"relation":"research_data","id":"9849","status":"public"},{"relation":"research_data","id":"9850","status":"public"},{"status":"public","id":"9851","relation":"research_data"},{"status":"public","relation":"research_data","id":"9852"},{"id":"6263","relation":"dissertation_contains","status":"public"}]},"day":"18","author":[{"id":"4342E402-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-2519-8004","last_name":"Lukacisinova","full_name":"Lukacisinova, Marta","first_name":"Marta"},{"first_name":"Sebastian","full_name":"Novak, Sebastian","last_name":"Novak","id":"461468AE-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-2519-824X"},{"id":"2C5658E6-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-2361-3953","last_name":"Paixao","full_name":"Paixao, Tiago","first_name":"Tiago"}],"type":"journal_article","citation":{"chicago":"Lukacisinova, Marta, Sebastian Novak, and Tiago Paixao. “Stress Induced Mutagenesis: Stress Diversity Facilitates the Persistence of Mutator Genes.” <i>PLoS Computational Biology</i>. Public Library of Science, 2017. <a href=\"https://doi.org/10.1371/journal.pcbi.1005609\">https://doi.org/10.1371/journal.pcbi.1005609</a>.","ista":"Lukacisinova M, Novak S, Paixao T. 2017. Stress induced mutagenesis: Stress diversity facilitates the persistence of mutator genes. PLoS Computational Biology. 13(7), e1005609.","ieee":"M. Lukacisinova, S. Novak, and T. Paixao, “Stress induced mutagenesis: Stress diversity facilitates the persistence of mutator genes,” <i>PLoS Computational Biology</i>, vol. 13, no. 7. Public Library of Science, 2017.","mla":"Lukacisinova, Marta, et al. “Stress Induced Mutagenesis: Stress Diversity Facilitates the Persistence of Mutator Genes.” <i>PLoS Computational Biology</i>, vol. 13, no. 7, e1005609, Public Library of Science, 2017, doi:<a href=\"https://doi.org/10.1371/journal.pcbi.1005609\">10.1371/journal.pcbi.1005609</a>.","short":"M. Lukacisinova, S. Novak, T. Paixao, PLoS Computational Biology 13 (2017).","ama":"Lukacisinova M, Novak S, Paixao T. Stress induced mutagenesis: Stress diversity facilitates the persistence of mutator genes. <i>PLoS Computational Biology</i>. 2017;13(7). doi:<a href=\"https://doi.org/10.1371/journal.pcbi.1005609\">10.1371/journal.pcbi.1005609</a>","apa":"Lukacisinova, M., Novak, S., &#38; Paixao, T. (2017). Stress induced mutagenesis: Stress diversity facilitates the persistence of mutator genes. <i>PLoS Computational Biology</i>. Public Library of Science. <a href=\"https://doi.org/10.1371/journal.pcbi.1005609\">https://doi.org/10.1371/journal.pcbi.1005609</a>"},"ec_funded":1,"title":"Stress induced mutagenesis: Stress diversity facilitates the persistence of mutator genes","publication":"PLoS Computational Biology","quality_controlled":"1","department":[{"_id":"ToBo"},{"_id":"NiBa"},{"_id":"CaGu"}],"intvolume":"        13","status":"public","publisher":"Public Library of Science","month":"07","date_created":"2018-12-11T11:47:58Z","scopus_import":1,"date_updated":"2024-03-25T23:30:14Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"issn":["1553734X"]},"article_type":"original","publist_id":"7004","has_accepted_license":"1","oa_version":"Published Version","year":"2017","file_date_updated":"2020-07-14T12:47:46Z","pubrep_id":"894","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)"},"volume":13,"publication_status":"published","oa":1,"file":[{"file_id":"5117","relation":"main_file","content_type":"application/pdf","date_created":"2018-12-12T10:15:01Z","creator":"system","file_size":3775716,"file_name":"IST-2017-894-v1+1_journal.pcbi.1005609.pdf","access_level":"open_access","date_updated":"2020-07-14T12:47:46Z","checksum":"9143c290fa6458ed2563bff4b295554a"}],"article_number":"e1005609","abstract":[{"text":"Mutator strains are expected to evolve when the availability and effect of beneficial mutations are high enough to counteract the disadvantage from deleterious mutations that will inevitably accumulate. As the population becomes more adapted to its environment, both availability and effect of beneficial mutations necessarily decrease and mutation rates are predicted to decrease. It has been shown that certain molecular mechanisms can lead to increased mutation rates when the organism finds itself in a stressful environment. While this may be a correlated response to other functions, it could also be an adaptive mechanism, raising mutation rates only when it is most advantageous. Here, we use a mathematical model to investigate the plausibility of the adaptive hypothesis. We show that such a mechanism can be mantained if the population is subjected to diverse stresses. By simulating various antibiotic treatment schemes, we find that combination treatments can reduce the effectiveness of second-order selection on stress-induced mutagenesis. We discuss the implications of our results to strategies of antibiotic therapy.","lang":"eng"}],"_id":"696","date_published":"2017-07-18T00:00:00Z","issue":"7"},{"ddc":["005"],"doi":"10.4230/LIPIcs.ICALP.2017.39","language":[{"iso":"eng"}],"project":[{"grant_number":"682815","name":"Teaching Old Crypto New Tricks","_id":"258AA5B2-B435-11E9-9278-68D0E5697425","call_identifier":"H2020"}],"author":[{"orcid":"0000-0002-9139-1654","id":"3E04A7AA-F248-11E8-B48F-1D18A9856A87","last_name":"Pietrzak","full_name":"Pietrzak, Krzysztof Z","first_name":"Krzysztof Z"},{"last_name":"Skórski","full_name":"Skórski, Maciej","first_name":"Maciej","id":"EC09FA6A-02D0-11E9-8223-86B7C91467DD"}],"type":"conference","alternative_title":["LIPIcs"],"day":"01","title":"Non uniform attacks against pseudoentropy","conference":{"end_date":"2017-07-14","start_date":"2017-07-10","name":"ICALP: International Colloquium on Automata, Languages, and Programming","location":"Warsaw, Poland"},"citation":{"short":"K.Z. Pietrzak, M. Skórski, in:, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2017.","apa":"Pietrzak, K. Z., &#38; Skórski, M. (2017). Non uniform attacks against pseudoentropy (Vol. 80). Presented at the ICALP: International Colloquium on Automata, Languages, and Programming, Warsaw, Poland: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. <a href=\"https://doi.org/10.4230/LIPIcs.ICALP.2017.39\">https://doi.org/10.4230/LIPIcs.ICALP.2017.39</a>","ama":"Pietrzak KZ, Skórski M. Non uniform attacks against pseudoentropy. In: Vol 80. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2017. doi:<a href=\"https://doi.org/10.4230/LIPIcs.ICALP.2017.39\">10.4230/LIPIcs.ICALP.2017.39</a>","ieee":"K. Z. Pietrzak and M. Skórski, “Non uniform attacks against pseudoentropy,” presented at the ICALP: International Colloquium on Automata, Languages, and Programming, Warsaw, Poland, 2017, vol. 80.","ista":"Pietrzak KZ, Skórski M. 2017. Non uniform attacks against pseudoentropy. ICALP: International Colloquium on Automata, Languages, and Programming, LIPIcs, vol. 80, 39.","chicago":"Pietrzak, Krzysztof Z, and Maciej Skórski. “Non Uniform Attacks against Pseudoentropy,” Vol. 80. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2017. <a href=\"https://doi.org/10.4230/LIPIcs.ICALP.2017.39\">https://doi.org/10.4230/LIPIcs.ICALP.2017.39</a>.","mla":"Pietrzak, Krzysztof Z., and Maciej Skórski. <i>Non Uniform Attacks against Pseudoentropy</i>. Vol. 80, 39, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2017, doi:<a href=\"https://doi.org/10.4230/LIPIcs.ICALP.2017.39\">10.4230/LIPIcs.ICALP.2017.39</a>."},"ec_funded":1,"status":"public","intvolume":"        80","quality_controlled":"1","department":[{"_id":"KrPi"}],"publisher":"Schloss Dagstuhl - Leibniz-Zentrum für Informatik","date_created":"2018-12-11T11:47:59Z","month":"07","publication_identifier":{"issn":["18688969"]},"scopus_import":1,"date_updated":"2021-01-12T08:11:15Z","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","year":"2017","oa_version":"Published Version","has_accepted_license":"1","publist_id":"7003","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)"},"pubrep_id":"893","volume":80,"file_date_updated":"2020-07-14T12:47:46Z","oa":1,"publication_status":"published","date_published":"2017-07-01T00:00:00Z","_id":"697","abstract":[{"lang":"eng","text":"De, Trevisan and Tulsiani [CRYPTO 2010] show that every distribution over n-bit strings which has constant statistical distance to uniform (e.g., the output of a pseudorandom generator mapping n-1 to n bit strings), can be distinguished from the uniform distribution with advantage epsilon by a circuit of size O( 2^n epsilon^2). We generalize this result, showing that a distribution which has less than k bits of min-entropy, can be distinguished from any distribution with k bits of delta-smooth min-entropy with advantage epsilon by a circuit of size O(2^k epsilon^2/delta^2). As a special case, this implies that any distribution with support at most 2^k (e.g., the output of a pseudoentropy generator mapping k to n bit strings) can be distinguished from any given distribution with min-entropy k+1 with advantage epsilon by a circuit of size O(2^k epsilon^2). Our result thus shows that pseudoentropy distributions face basically the same non-uniform attacks as pseudorandom distributions. "}],"file":[{"date_updated":"2020-07-14T12:47:46Z","access_level":"open_access","checksum":"e95618a001692f1af2d68f5fde43bc1f","file_name":"IST-2017-893-v1+1_LIPIcs-ICALP-2017-39.pdf","file_size":601004,"creator":"system","date_created":"2018-12-12T10:08:40Z","content_type":"application/pdf","file_id":"4701","relation":"main_file"}],"article_number":"39"},{"oa":1,"publication_status":"published","volume":28,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode","image":"/images/cc_by_nc_sa.png","name":"Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)","short":"CC BY-NC-SA (4.0)"},"pubrep_id":"892","file_date_updated":"2020-07-14T12:47:46Z","issue":"14","abstract":[{"lang":"eng","text":"Extracellular matrix signals from the microenvironment regulate gene expression patterns and cell behavior. Using a combination of experiments and geometric models, we demonstrate correlations between cell geometry, three-dimensional (3D) organization of chromosome territories, and gene expression. Fluorescence in situ hybridization experiments showed that micropatterned fibroblasts cultured on anisotropic versus isotropic substrates resulted in repositioning of specific chromosomes, which contained genes that were differentially regulated by cell geometries. Experiments combined with ellipsoid packing models revealed that the mechanosensitivity of chromosomes was correlated with their orientation in the nucleus. Transcription inhibition experiments suggested that the intermingling degree was more sensitive to global changes in transcription than to chromosome radial positioning and its orientations. These results suggested that cell geometry modulated 3D chromosome arrangement, and their neighborhoods correlated with gene expression patterns in a predictable manner. This is central to understanding geometric control of genetic programs involved in cellular homeostasis and the associated diseases. "}],"_id":"698","date_published":"2017-07-07T00:00:00Z","file":[{"date_created":"2018-12-12T10:10:53Z","content_type":"application/pdf","file_id":"4844","relation":"main_file","date_updated":"2020-07-14T12:47:46Z","access_level":"open_access","checksum":"de01dac9e30970cfa6ae902480a4e04d","file_name":"IST-2017-892-v1+1_Mol._Biol._Cell-2017-Wang-1997-2009.pdf","file_size":1086097,"creator":"system"}],"publication_identifier":{"issn":["10591524"]},"date_updated":"2021-01-12T08:11:17Z","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","scopus_import":1,"year":"2017","has_accepted_license":"1","oa_version":"Published Version","publist_id":"7001","publisher":"American Society for Cell Biology","status":"public","intvolume":"        28","department":[{"_id":"CaUh"}],"quality_controlled":"1","publication":"Molecular Biology of the Cell","page":"1997 - 2009","date_created":"2018-12-11T11:47:59Z","month":"07","project":[{"call_identifier":"FWF","_id":"2530CA10-B435-11E9-9278-68D0E5697425","name":"Gaussian Graphical Models: Theory and Applications","grant_number":"Y 903-N35"}],"doi":"10.1091/mbc.E16-12-0825","ddc":["519"],"language":[{"iso":"eng"}],"title":"Orientation and repositioning of chromosomes correlate with cell geometry dependent gene expression","citation":{"mla":"Wang, Yejun, et al. “Orientation and Repositioning of Chromosomes Correlate with Cell Geometry Dependent Gene Expression.” <i>Molecular Biology of the Cell</i>, vol. 28, no. 14, American Society for Cell Biology, 2017, pp. 1997–2009, doi:<a href=\"https://doi.org/10.1091/mbc.E16-12-0825\">10.1091/mbc.E16-12-0825</a>.","chicago":"Wang, Yejun, Mallika Nagarajan, Caroline Uhler, and Gv Shivashankar. “Orientation and Repositioning of Chromosomes Correlate with Cell Geometry Dependent Gene Expression.” <i>Molecular Biology of the Cell</i>. American Society for Cell Biology, 2017. <a href=\"https://doi.org/10.1091/mbc.E16-12-0825\">https://doi.org/10.1091/mbc.E16-12-0825</a>.","ista":"Wang Y, Nagarajan M, Uhler C, Shivashankar G. 2017. Orientation and repositioning of chromosomes correlate with cell geometry dependent gene expression. Molecular Biology of the Cell. 28(14), 1997–2009.","ieee":"Y. Wang, M. Nagarajan, C. Uhler, and G. Shivashankar, “Orientation and repositioning of chromosomes correlate with cell geometry dependent gene expression,” <i>Molecular Biology of the Cell</i>, vol. 28, no. 14. American Society for Cell Biology, pp. 1997–2009, 2017.","ama":"Wang Y, Nagarajan M, Uhler C, Shivashankar G. Orientation and repositioning of chromosomes correlate with cell geometry dependent gene expression. <i>Molecular Biology of the Cell</i>. 2017;28(14):1997-2009. doi:<a href=\"https://doi.org/10.1091/mbc.E16-12-0825\">10.1091/mbc.E16-12-0825</a>","apa":"Wang, Y., Nagarajan, M., Uhler, C., &#38; Shivashankar, G. (2017). Orientation and repositioning of chromosomes correlate with cell geometry dependent gene expression. <i>Molecular Biology of the Cell</i>. American Society for Cell Biology. <a href=\"https://doi.org/10.1091/mbc.E16-12-0825\">https://doi.org/10.1091/mbc.E16-12-0825</a>","short":"Y. Wang, M. Nagarajan, C. Uhler, G. Shivashankar, Molecular Biology of the Cell 28 (2017) 1997–2009."},"author":[{"first_name":"Yejun","full_name":"Wang, Yejun","last_name":"Wang"},{"full_name":"Nagarajan, Mallika","first_name":"Mallika","last_name":"Nagarajan"},{"last_name":"Uhler","full_name":"Uhler, Caroline","first_name":"Caroline","orcid":"0000-0002-7008-0216","id":"49ADD78E-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Gv","full_name":"Shivashankar, Gv","last_name":"Shivashankar"}],"type":"journal_article","day":"07"},{"volume":114,"publication_status":"published","oa":1,"main_file_link":[{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502615/","open_access":"1"}],"date_published":"2017-07-03T00:00:00Z","_id":"699","abstract":[{"lang":"eng","text":"In antagonistic symbioses, such as host–parasite interactions, one population’s success is the other’s loss. In mutualistic symbioses, such as division of labor, both parties can gain, but they might have different preferences over the possible mutualistic arrangements. The rates of evolution of the two populations in a symbiosis are important determinants of which population will be more successful: Faster evolution is thought to be favored in antagonistic symbioses (the “Red Queen effect”), but disfavored in certain mutualistic symbioses (the “Red King effect”). However, it remains unclear which biological parameters drive these effects. Here, we analyze the effects of the various determinants of evolutionary rate: generation time, mutation rate, population size, and the intensity of natural selection. Our main results hold for the case where mutation is infrequent. Slower evolution causes a long-term advantage in an important class of mutualistic interactions. Surprisingly, less intense selection is the strongest driver of this Red King effect, whereas relative mutation rates and generation times have little effect. In antagonistic interactions, faster evolution by any means is beneficial. Our results provide insight into the demographic evolution of symbionts. "}],"issue":"27","date_updated":"2021-01-12T08:11:21Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","external_id":{"pmid":["28630336"]},"scopus_import":1,"publication_identifier":{"issn":["00278424"]},"publist_id":"7002","year":"2017","oa_version":"Submitted Version","quality_controlled":"1","department":[{"_id":"KrCh"}],"publication":"PNAS","intvolume":"       114","status":"public","publisher":"National Academy of Sciences","month":"07","date_created":"2018-12-11T11:48:00Z","page":"E5396 - E5405","language":[{"iso":"eng"}],"doi":"10.1073/pnas.1702020114","pmid":1,"day":"03","author":[{"last_name":"Veller","first_name":"Carl","full_name":"Veller, Carl"},{"first_name":"Laura","full_name":"Hayward, Laura","last_name":"Hayward"},{"last_name":"Nowak","full_name":"Nowak, Martin","first_name":"Martin"},{"id":"2FDF8F3C-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5116-955X","last_name":"Hilbe","first_name":"Christian","full_name":"Hilbe, Christian"}],"type":"journal_article","citation":{"short":"C. Veller, L. Hayward, M. Nowak, C. Hilbe, PNAS 114 (2017) E5396–E5405.","ama":"Veller C, Hayward L, Nowak M, Hilbe C. The red queen and king in finite populations. <i>PNAS</i>. 2017;114(27):E5396-E5405. doi:<a href=\"https://doi.org/10.1073/pnas.1702020114\">10.1073/pnas.1702020114</a>","apa":"Veller, C., Hayward, L., Nowak, M., &#38; Hilbe, C. (2017). The red queen and king in finite populations. <i>PNAS</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.1702020114\">https://doi.org/10.1073/pnas.1702020114</a>","chicago":"Veller, Carl, Laura Hayward, Martin Nowak, and Christian Hilbe. “The Red Queen and King in Finite Populations.” <i>PNAS</i>. National Academy of Sciences, 2017. <a href=\"https://doi.org/10.1073/pnas.1702020114\">https://doi.org/10.1073/pnas.1702020114</a>.","ieee":"C. Veller, L. Hayward, M. Nowak, and C. Hilbe, “The red queen and king in finite populations,” <i>PNAS</i>, vol. 114, no. 27. National Academy of Sciences, pp. E5396–E5405, 2017.","ista":"Veller C, Hayward L, Nowak M, Hilbe C. 2017. The red queen and king in finite populations. PNAS. 114(27), E5396–E5405.","mla":"Veller, Carl, et al. “The Red Queen and King in Finite Populations.” <i>PNAS</i>, vol. 114, no. 27, National Academy of Sciences, 2017, pp. E5396–405, doi:<a href=\"https://doi.org/10.1073/pnas.1702020114\">10.1073/pnas.1702020114</a>."},"title":"The red queen and king in finite populations"},{"volume":96,"publication_status":"published","main_file_link":[{"url":"https://arxiv.org/pdf/1612.07061.pdf","open_access":"1"}],"oa":1,"article_number":"012404","abstract":[{"lang":"eng","text":"Microtubules provide the mechanical force required for chromosome separation during mitosis. However, little is known about the dynamic (high-frequency) mechanical properties of microtubules. Here, we theoretically propose to control the vibrations of a doubly clamped microtubule by tip electrodes and to detect its motion via the optomechanical coupling between the vibrational modes of the microtubule and an optical cavity. In the presence of a red-detuned strong pump laser, this coupling leads to optomechanical-induced transparency of an optical probe field, which can be detected with state-of-the art technology. The center frequency and line width of the transparency peak give the resonance frequency and damping rate of the microtubule, respectively, while the height of the peak reveals information about the microtubule-cavity field coupling. Our method opens the new possibilities to gain information about the physical properties of microtubules, which will enhance our capability to design physical cancer treatment protocols as alternatives to chemotherapeutic drugs."}],"_id":"700","date_published":"2017-07-12T00:00:00Z","issue":"1","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","date_updated":"2023-02-23T12:56:35Z","scopus_import":1,"publication_identifier":{"issn":["24700045"]},"publist_id":"6997","oa_version":"Submitted Version","year":"2017","quality_controlled":"1","department":[{"_id":"JoFi"}],"publication":" Physical Review E Statistical Nonlinear and Soft Matter Physics ","intvolume":"        96","status":"public","publisher":"American Institute of Physics","month":"07","date_created":"2018-12-11T11:48:00Z","language":[{"iso":"eng"}],"doi":"10.1103/PhysRevE.96.012404","project":[{"name":"Microwave-to-Optical Quantum Link: Quantum Teleportation and Quantum Illumination with cavity Optomechanics","grant_number":"707438","_id":"258047B6-B435-11E9-9278-68D0E5697425","call_identifier":"H2020"}],"day":"12","author":[{"orcid":"0000-0003-0415-1423","id":"2D25E1F6-F248-11E8-B48F-1D18A9856A87","last_name":"Barzanjeh","full_name":"Barzanjeh, Shabir","first_name":"Shabir"},{"first_name":"Vahid","full_name":"Salari, Vahid","last_name":"Salari"},{"last_name":"Tuszynski","first_name":"Jack","full_name":"Tuszynski, Jack"},{"first_name":"Michal","full_name":"Cifra, Michal","last_name":"Cifra"},{"first_name":"Christoph","full_name":"Simon, Christoph","last_name":"Simon"}],"type":"journal_article","ec_funded":1,"citation":{"short":"S. Barzanjeh, V. Salari, J. Tuszynski, M. Cifra, C. Simon,  Physical Review E Statistical Nonlinear and Soft Matter Physics  96 (2017).","ama":"Barzanjeh S, Salari V, Tuszynski J, Cifra M, Simon C. Optomechanical proposal for monitoring microtubule mechanical vibrations. <i> Physical Review E Statistical Nonlinear and Soft Matter Physics </i>. 2017;96(1). doi:<a href=\"https://doi.org/10.1103/PhysRevE.96.012404\">10.1103/PhysRevE.96.012404</a>","apa":"Barzanjeh, S., Salari, V., Tuszynski, J., Cifra, M., &#38; Simon, C. (2017). Optomechanical proposal for monitoring microtubule mechanical vibrations. <i> Physical Review E Statistical Nonlinear and Soft Matter Physics </i>. American Institute of Physics. <a href=\"https://doi.org/10.1103/PhysRevE.96.012404\">https://doi.org/10.1103/PhysRevE.96.012404</a>","chicago":"Barzanjeh, Shabir, Vahid Salari, Jack Tuszynski, Michal Cifra, and Christoph Simon. “Optomechanical Proposal for Monitoring Microtubule Mechanical Vibrations.” <i> Physical Review E Statistical Nonlinear and Soft Matter Physics </i>. American Institute of Physics, 2017. <a href=\"https://doi.org/10.1103/PhysRevE.96.012404\">https://doi.org/10.1103/PhysRevE.96.012404</a>.","ista":"Barzanjeh S, Salari V, Tuszynski J, Cifra M, Simon C. 2017. Optomechanical proposal for monitoring microtubule mechanical vibrations.  Physical Review E Statistical Nonlinear and Soft Matter Physics . 96(1), 012404.","ieee":"S. Barzanjeh, V. Salari, J. Tuszynski, M. Cifra, and C. Simon, “Optomechanical proposal for monitoring microtubule mechanical vibrations,” <i> Physical Review E Statistical Nonlinear and Soft Matter Physics </i>, vol. 96, no. 1. American Institute of Physics, 2017.","mla":"Barzanjeh, Shabir, et al. “Optomechanical Proposal for Monitoring Microtubule Mechanical Vibrations.” <i> Physical Review E Statistical Nonlinear and Soft Matter Physics </i>, vol. 96, no. 1, 012404, American Institute of Physics, 2017, doi:<a href=\"https://doi.org/10.1103/PhysRevE.96.012404\">10.1103/PhysRevE.96.012404</a>."},"title":"Optomechanical proposal for monitoring microtubule mechanical vibrations"},{"language":[{"iso":"eng"}],"ddc":["500"],"citation":{"short":"J. Kynčl, Z. Patakova, The Electronic Journal of Combinatorics 24 (2017) 1–44.","apa":"Kynčl, J., &#38; Patakova, Z. (2017). On the nonexistence of k reptile simplices in ℝ^3 and ℝ^4. <i>The Electronic Journal of Combinatorics</i>. International Press.","ama":"Kynčl J, Patakova Z. On the nonexistence of k reptile simplices in ℝ^3 and ℝ^4. <i>The Electronic Journal of Combinatorics</i>. 2017;24(3):1-44.","ista":"Kynčl J, Patakova Z. 2017. On the nonexistence of k reptile simplices in ℝ^3 and ℝ^4. The Electronic Journal of Combinatorics. 24(3), 1–44.","ieee":"J. Kynčl and Z. Patakova, “On the nonexistence of k reptile simplices in ℝ^3 and ℝ^4,” <i>The Electronic Journal of Combinatorics</i>, vol. 24, no. 3. International Press, pp. 1–44, 2017.","chicago":"Kynčl, Jan, and Zuzana Patakova. “On the Nonexistence of k Reptile Simplices in ℝ^3 and ℝ^4.” <i>The Electronic Journal of Combinatorics</i>. International Press, 2017.","mla":"Kynčl, Jan, and Zuzana Patakova. “On the Nonexistence of k Reptile Simplices in ℝ^3 and ℝ^4.” <i>The Electronic Journal of Combinatorics</i>, vol. 24, no. 3, International Press, 2017, pp. 1–44."},"title":"On the nonexistence of k reptile simplices in ℝ^3 and ℝ^4","day":"14","type":"journal_article","author":[{"first_name":"Jan","full_name":"Kynčl, Jan","last_name":"Kynčl"},{"orcid":"0000-0002-3975-1683","id":"48B57058-F248-11E8-B48F-1D18A9856A87","last_name":"Patakova","first_name":"Zuzana","full_name":"Patakova, Zuzana"}],"publisher":"International Press","publication":"The Electronic Journal of Combinatorics","department":[{"_id":"UlWa"}],"quality_controlled":"1","status":"public","intvolume":"        24","page":"1-44","month":"07","date_created":"2018-12-11T11:48:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2021-01-12T08:11:28Z","publication_identifier":{"issn":["10778926"]},"publist_id":"6996","has_accepted_license":"1","year":"2017","oa_version":"Submitted Version","publication_status":"published","oa":1,"file_date_updated":"2020-07-14T12:47:47Z","pubrep_id":"984","volume":24,"issue":"3","file":[{"file_name":"IST-2018-984-v1+1_Patakova_on_the_nonexistence_of_k-reptile_simplices_in_R_3_and_R_4_2017.pdf","file_size":544042,"creator":"system","checksum":"a431e573e31df13bc0f66de3061006ec","date_updated":"2020-07-14T12:47:47Z","access_level":"open_access","content_type":"application/pdf","relation":"main_file","file_id":"5077","date_created":"2018-12-12T10:14:25Z"}],"_id":"701","date_published":"2017-07-14T00:00:00Z","abstract":[{"text":"A d-dimensional simplex S is called a k-reptile (or a k-reptile simplex) if it can be tiled by k simplices with disjoint interiors that are all mutually congruent and similar to S. For d = 2, triangular k-reptiles exist for all k of the form a^2, 3a^2 or a^2+b^2 and they have been completely characterized by Snover, Waiveris, and Williams. On the other hand, the only k-reptile simplices that are known for d ≥ 3, have k = m^d, where m is a positive integer. We substantially simplify the proof by Matoušek and the second author that for d = 3, k-reptile tetrahedra can exist only for k = m^3. We then prove a weaker analogue of this result for d = 4 by showing that four-dimensional k-reptile simplices can exist only for k = m^2.","lang":"eng"}]},{"publication_identifier":{"issn":["19466234"]},"doi":"10.1126/scitranslmed.aao0972","scopus_import":1,"language":[{"iso":"eng"}],"date_updated":"2021-01-12T08:11:31Z","user_id":"4435EBFC-F248-11E8-B48F-1D18A9856A87","title":"The riddle of CHD8 haploinsufficiency in autism spectrum disorder","citation":{"short":"G. Novarino, Science Translational Medicine 9 (2017) eaao0972.","ama":"Novarino G. The riddle of CHD8 haploinsufficiency in autism spectrum disorder. <i>Science Translational Medicine</i>. 2017;9(399):eaao0972. doi:<a href=\"https://doi.org/10.1126/scitranslmed.aao0972\">10.1126/scitranslmed.aao0972</a>","apa":"Novarino, G. (2017). The riddle of CHD8 haploinsufficiency in autism spectrum disorder. <i>Science Translational Medicine</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/scitranslmed.aao0972\">https://doi.org/10.1126/scitranslmed.aao0972</a>","chicago":"Novarino, Gaia. “The Riddle of CHD8 Haploinsufficiency in Autism Spectrum Disorder.” <i>Science Translational Medicine</i>. American Association for the Advancement of Science, 2017. <a href=\"https://doi.org/10.1126/scitranslmed.aao0972\">https://doi.org/10.1126/scitranslmed.aao0972</a>.","ieee":"G. Novarino, “The riddle of CHD8 haploinsufficiency in autism spectrum disorder,” <i>Science Translational Medicine</i>, vol. 9, no. 399. American Association for the Advancement of Science, p. eaao0972, 2017.","ista":"Novarino G. 2017. The riddle of CHD8 haploinsufficiency in autism spectrum disorder. Science Translational Medicine. 9(399), eaao0972.","mla":"Novarino, Gaia. “The Riddle of CHD8 Haploinsufficiency in Autism Spectrum Disorder.” <i>Science Translational Medicine</i>, vol. 9, no. 399, American Association for the Advancement of Science, 2017, p. eaao0972, doi:<a href=\"https://doi.org/10.1126/scitranslmed.aao0972\">10.1126/scitranslmed.aao0972</a>."},"type":"journal_article","author":[{"orcid":"0000-0002-7673-7178","id":"3E57A680-F248-11E8-B48F-1D18A9856A87","last_name":"Novarino","full_name":"Novarino, Gaia","first_name":"Gaia"}],"oa_version":"None","year":"2017","publist_id":"6993","day":"19","publication_status":"published","publisher":"American Association for the Advancement of Science","intvolume":"         9","status":"public","volume":9,"publication":"Science Translational Medicine","department":[{"_id":"GaNo"}],"quality_controlled":"1","issue":"399","page":"eaao0972","date_published":"2017-07-19T00:00:00Z","_id":"702","date_created":"2018-12-11T11:48:01Z","abstract":[{"lang":"eng","text":"Leading autism-associated mutation in mouse partially mimics human disorder.\r\n\r\n"}],"month":"07"},{"month":"07","date_created":"2018-12-11T11:48:01Z","publisher":"eLife Sciences Publications","publication":"eLife","department":[{"_id":"CaGu"}],"quality_controlled":"1","intvolume":"         6","status":"public","citation":{"short":"M. Steinrück, C.C. Guet, ELife 6 (2017).","ama":"Steinrück M, Guet CC. Complex chromosomal neighborhood effects determine the adaptive potential of a gene under selection. <i>eLife</i>. 2017;6. doi:<a href=\"https://doi.org/10.7554/eLife.25100\">10.7554/eLife.25100</a>","apa":"Steinrück, M., &#38; Guet, C. C. (2017). Complex chromosomal neighborhood effects determine the adaptive potential of a gene under selection. <i>ELife</i>. eLife Sciences Publications. <a href=\"https://doi.org/10.7554/eLife.25100\">https://doi.org/10.7554/eLife.25100</a>","chicago":"Steinrück, Magdalena, and Calin C Guet. “Complex Chromosomal Neighborhood Effects Determine the Adaptive Potential of a Gene under Selection.” <i>ELife</i>. eLife Sciences Publications, 2017. <a href=\"https://doi.org/10.7554/eLife.25100\">https://doi.org/10.7554/eLife.25100</a>.","ieee":"M. Steinrück and C. C. Guet, “Complex chromosomal neighborhood effects determine the adaptive potential of a gene under selection,” <i>eLife</i>, vol. 6. eLife Sciences Publications, 2017.","ista":"Steinrück M, Guet CC. 2017. Complex chromosomal neighborhood effects determine the adaptive potential of a gene under selection. eLife. 6, e25100.","mla":"Steinrück, Magdalena, and Calin C. Guet. “Complex Chromosomal Neighborhood Effects Determine the Adaptive Potential of a Gene under Selection.” <i>ELife</i>, vol. 6, e25100, eLife Sciences Publications, 2017, doi:<a href=\"https://doi.org/10.7554/eLife.25100\">10.7554/eLife.25100</a>."},"title":"Complex chromosomal neighborhood effects determine the adaptive potential of a gene under selection","day":"25","type":"journal_article","author":[{"id":"2C023F40-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-1229-9719","last_name":"Steinrück","first_name":"Magdalena","full_name":"Steinrück, Magdalena"},{"orcid":"0000-0001-6220-2052","id":"47F8433E-F248-11E8-B48F-1D18A9856A87","last_name":"Guet","first_name":"Calin C","full_name":"Guet, Calin C"}],"related_material":{"record":[{"id":"5564","relation":"popular_science","status":"public"},{"status":"public","id":"26","relation":"dissertation_contains"}]},"language":[{"iso":"eng"}],"doi":"10.7554/eLife.25100","ddc":["576"],"article_number":"e25100","file":[{"file_name":"IST-2017-890-v1+1_elife-25100-v1.pdf","file_size":2092088,"creator":"system","checksum":"6b908b5db9f61f6820ebd7f8fa815571","date_updated":"2020-07-14T12:47:48Z","access_level":"open_access","content_type":"application/pdf","relation":"main_file","file_id":"4975","date_created":"2018-12-12T10:12:54Z"},{"creator":"system","file_size":3428681,"file_name":"IST-2017-890-v1+2_elife-25100-figures-v1.pdf","access_level":"open_access","date_updated":"2020-07-14T12:47:48Z","checksum":"ca21530389b720243552678125fdba35","relation":"main_file","file_id":"4976","content_type":"application/pdf","date_created":"2018-12-12T10:12:55Z"}],"_id":"704","date_published":"2017-07-25T00:00:00Z","abstract":[{"lang":"eng","text":"How the organization of genes on a chromosome shapes adaptation is essential for understanding evolutionary paths. Here, we investigate how adaptation to rapidly increasing levels of antibiotic depends on the chromosomal neighborhood of a drug-resistance gene inserted at different positions of the Escherichia coli chromosome. Using a dual-fluorescence reporter that allows us to distinguish gene amplifications from other up-mutations, we track in real-time adaptive changes in expression of the drug-resistance gene. We find that the relative contribution of several mutation types differs systematically between loci due to properties of neighboring genes: essentiality, expression, orientation, termination, and presence of duplicates. These properties determine rate and fitness effects of gene amplification, deletions, and mutations compromising transcriptional termination. Thus, the adaptive potential of a gene under selection is a system-property with a complex genetic basis that is specific for each chromosomal locus, and it can be inferred from detailed functional and genomic data."}],"publication_status":"published","oa":1,"file_date_updated":"2020-07-14T12:47:48Z","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)"},"pubrep_id":"890","volume":6,"publist_id":"6990","has_accepted_license":"1","oa_version":"Published Version","year":"2017","scopus_import":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2024-03-25T23:30:14Z","publication_identifier":{"issn":["2050084X"]}},{"volume":22,"intvolume":"        22","status":"public","quality_controlled":"1","department":[{"_id":"PeJo"}],"publication":"Genes to Cells","publication_status":"published","publisher":"Wiley-Blackwell","_id":"706","abstract":[{"lang":"eng","text":"A hippocampal mossy fiber synapse has a complex structure and is implicated in learning and memory. In this synapse, the mossy fiber boutons attach to the dendritic shaft by puncta adherentia junctions and wrap around a multiply-branched spine, forming synaptic junctions. We have recently shown using transmission electron microscopy, immunoelectron microscopy and serial block face-scanning electron microscopy that atypical puncta adherentia junctions are formed in the afadin-deficient mossy fiber synapse and that the complexity of postsynaptic spines and mossy fiber boutons, the number of spine heads, the area of postsynaptic densities and the density of synaptic vesicles docked to active zones are decreased in the afadin-deficient synapse. We investigated here the roles of afadin in the functional differentiations of the mossy fiber synapse using the afadin-deficient mice. The electrophysiological studies showed that both the release probability of glutamate and the postsynaptic responsiveness to glutamate were markedly reduced, but not completely lost, in the afadin-deficient mossy fiber synapse, whereas neither long-term potentiation nor long-term depression was affected. These results indicate that afadin plays roles in the functional differentiations of the presynapse and the postsynapse of the hippocampal mossy fiber synapse."}],"date_published":"2017-08-01T00:00:00Z","date_created":"2018-12-11T11:48:02Z","month":"08","issue":"8","page":"715 - 722","doi":"10.1111/gtc.12508","publication_identifier":{"issn":["13569597"]},"user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","date_updated":"2021-01-12T08:11:37Z","language":[{"iso":"eng"}],"scopus_import":1,"year":"2017","oa_version":"None","type":"journal_article","author":[{"full_name":"Geng, Xiaoqi","first_name":"Xiaoqi","last_name":"Geng","id":"3395256A-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Tomohiko","full_name":"Maruo, Tomohiko","last_name":"Maruo"},{"last_name":"Mandai","first_name":"Kenji","full_name":"Mandai, Kenji"},{"full_name":"Supriyanto, Irwan","first_name":"Irwan","last_name":"Supriyanto"},{"last_name":"Miyata","first_name":"Muneaki","full_name":"Miyata, Muneaki"},{"last_name":"Sakakibara","full_name":"Sakakibara, Shotaro","first_name":"Shotaro"},{"full_name":"Mizoguchi, Akira","first_name":"Akira","last_name":"Mizoguchi"},{"first_name":"Yoshimi","full_name":"Takai, Yoshimi","last_name":"Takai"},{"full_name":"Mori, Masahiro","first_name":"Masahiro","last_name":"Mori"}],"day":"01","publist_id":"6987","title":"Roles of afadin in functional differentiations of hippocampal mossy fiber synapse","citation":{"ama":"Geng X, Maruo T, Mandai K, et al. Roles of afadin in functional differentiations of hippocampal mossy fiber synapse. <i>Genes to Cells</i>. 2017;22(8):715-722. doi:<a href=\"https://doi.org/10.1111/gtc.12508\">10.1111/gtc.12508</a>","apa":"Geng, X., Maruo, T., Mandai, K., Supriyanto, I., Miyata, M., Sakakibara, S., … Mori, M. (2017). Roles of afadin in functional differentiations of hippocampal mossy fiber synapse. <i>Genes to Cells</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1111/gtc.12508\">https://doi.org/10.1111/gtc.12508</a>","short":"X. Geng, T. Maruo, K. Mandai, I. Supriyanto, M. Miyata, S. Sakakibara, A. Mizoguchi, Y. Takai, M. Mori, Genes to Cells 22 (2017) 715–722.","mla":"Geng, Xiaoqi, et al. “Roles of Afadin in Functional Differentiations of Hippocampal Mossy Fiber Synapse.” <i>Genes to Cells</i>, vol. 22, no. 8, Wiley-Blackwell, 2017, pp. 715–22, doi:<a href=\"https://doi.org/10.1111/gtc.12508\">10.1111/gtc.12508</a>.","chicago":"Geng, Xiaoqi, Tomohiko Maruo, Kenji Mandai, Irwan Supriyanto, Muneaki Miyata, Shotaro Sakakibara, Akira Mizoguchi, Yoshimi Takai, and Masahiro Mori. “Roles of Afadin in Functional Differentiations of Hippocampal Mossy Fiber Synapse.” <i>Genes to Cells</i>. Wiley-Blackwell, 2017. <a href=\"https://doi.org/10.1111/gtc.12508\">https://doi.org/10.1111/gtc.12508</a>.","ista":"Geng X, Maruo T, Mandai K, Supriyanto I, Miyata M, Sakakibara S, Mizoguchi A, Takai Y, Mori M. 2017. Roles of afadin in functional differentiations of hippocampal mossy fiber synapse. Genes to Cells. 22(8), 715–722.","ieee":"X. Geng <i>et al.</i>, “Roles of afadin in functional differentiations of hippocampal mossy fiber synapse,” <i>Genes to Cells</i>, vol. 22, no. 8. Wiley-Blackwell, pp. 715–722, 2017."}},{"publication_identifier":{"issn":["2041-1723"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2021-01-12T08:11:39Z","has_accepted_license":"1","year":"2017","oa_version":"Published Version","article_type":"original","volume":8,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)"},"file_date_updated":"2020-07-14T12:47:48Z","oa":1,"publication_status":"published","abstract":[{"text":"The complex antiferromagnetic orders observed in the honeycomb iridates are a double-edged sword in the search for a quantum spin-liquid: both attesting that the magnetic interactions provide many of the necessary ingredients, while simultaneously impeding access. Focus has naturally been drawn to the unusual magnetic orders that hint at the underlying spin correlations. However, the study of any particular broken symmetry state generally provides little clue about the possibility of other nearby ground states. Here we use magnetic fields approaching 100 Tesla to reveal the extent of the spin correlations in γ-lithium iridate. We find that a small component of field along the magnetic easy-axis melts long-range order, revealing a bistable, strongly correlated spin state. Far from the usual destruction of antiferromagnetism via spin polarization, the high-field state possesses only a small fraction of the total iridium moment, without evidence for long-range order up to the highest attainable magnetic fields.","lang":"eng"}],"_id":"7064","date_published":"2017-08-01T00:00:00Z","file":[{"date_created":"2019-11-20T14:12:54Z","file_id":"7091","relation":"main_file","content_type":"application/pdf","access_level":"open_access","date_updated":"2020-07-14T12:47:48Z","checksum":"57fcd59d2f274b6b16cc89ea03cfd440","file_size":1242958,"creator":"cziletti","file_name":"2017_NatureComm_Modic.pdf"}],"article_number":"180","issue":"1","article_processing_charge":"No","ddc":["530"],"doi":"10.1038/s41467-017-00264-6","language":[{"iso":"eng"}],"author":[{"last_name":"Modic","first_name":"Kimberly A","full_name":"Modic, Kimberly A","id":"13C26AC0-EB69-11E9-87C6-5F3BE6697425","orcid":"0000-0001-9760-3147"},{"last_name":"Ramshaw","full_name":"Ramshaw, B. J.","first_name":"B. J."},{"last_name":"Betts","full_name":"Betts, J. B.","first_name":"J. B."},{"last_name":"Breznay","full_name":"Breznay, Nicholas P.","first_name":"Nicholas P."},{"first_name":"James G.","full_name":"Analytis, James G.","last_name":"Analytis"},{"last_name":"McDonald","first_name":"Ross D.","full_name":"McDonald, Ross D."},{"first_name":"Arkady","full_name":"Shekhter, Arkady","last_name":"Shekhter"}],"type":"journal_article","day":"01","title":"Robust spin correlations at high magnetic fields in the harmonic honeycomb iridates","citation":{"chicago":"Modic, Kimberly A, B. J. Ramshaw, J. B. Betts, Nicholas P. Breznay, James G. Analytis, Ross D. McDonald, and Arkady Shekhter. “Robust Spin Correlations at High Magnetic Fields in the Harmonic Honeycomb Iridates.” <i>Nature Communications</i>. Springer Nature, 2017. <a href=\"https://doi.org/10.1038/s41467-017-00264-6\">https://doi.org/10.1038/s41467-017-00264-6</a>.","ieee":"K. A. Modic <i>et al.</i>, “Robust spin correlations at high magnetic fields in the harmonic honeycomb iridates,” <i>Nature Communications</i>, vol. 8, no. 1. Springer Nature, 2017.","ista":"Modic KA, Ramshaw BJ, Betts JB, Breznay NP, Analytis JG, McDonald RD, Shekhter A. 2017. Robust spin correlations at high magnetic fields in the harmonic honeycomb iridates. Nature Communications. 8(1), 180.","mla":"Modic, Kimberly A., et al. “Robust Spin Correlations at High Magnetic Fields in the Harmonic Honeycomb Iridates.” <i>Nature Communications</i>, vol. 8, no. 1, 180, Springer Nature, 2017, doi:<a href=\"https://doi.org/10.1038/s41467-017-00264-6\">10.1038/s41467-017-00264-6</a>.","short":"K.A. Modic, B.J. Ramshaw, J.B. Betts, N.P. Breznay, J.G. Analytis, R.D. McDonald, A. Shekhter, Nature Communications 8 (2017).","ama":"Modic KA, Ramshaw BJ, Betts JB, et al. Robust spin correlations at high magnetic fields in the harmonic honeycomb iridates. <i>Nature Communications</i>. 2017;8(1). doi:<a href=\"https://doi.org/10.1038/s41467-017-00264-6\">10.1038/s41467-017-00264-6</a>","apa":"Modic, K. A., Ramshaw, B. J., Betts, J. B., Breznay, N. P., Analytis, J. G., McDonald, R. D., &#38; Shekhter, A. (2017). Robust spin correlations at high magnetic fields in the harmonic honeycomb iridates. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-017-00264-6\">https://doi.org/10.1038/s41467-017-00264-6</a>"},"status":"public","intvolume":"         8","quality_controlled":"1","publication":"Nature Communications","publisher":"Springer Nature","date_created":"2019-11-19T13:11:55Z","extern":"1","month":"08"},{"date_updated":"2021-01-12T08:11:39Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","language":[{"iso":"eng"}],"publication_identifier":{"eissn":["2469-9969"],"issn":["2469-9950"]},"doi":"10.1103/physrevb.95.121106","article_type":"original","day":"27","type":"journal_article","author":[{"last_name":"Shekhter","first_name":"Arkady","full_name":"Shekhter, Arkady"},{"last_name":"Modic","first_name":"Kimberly A","full_name":"Modic, Kimberly A","id":"13C26AC0-EB69-11E9-87C6-5F3BE6697425","orcid":"0000-0001-9760-3147"},{"full_name":"McDonald, R. D.","first_name":"R. D.","last_name":"McDonald"},{"last_name":"Ramshaw","full_name":"Ramshaw, B. J.","first_name":"B. J."}],"year":"2017","oa_version":"None","citation":{"ieee":"A. Shekhter, K. A. Modic, R. D. McDonald, and B. J. Ramshaw, “Thermodynamic constraints on the amplitude of quantum oscillations,” <i>Physical Review B</i>, vol. 95, no. 12. APS, 2017.","ista":"Shekhter A, Modic KA, McDonald RD, Ramshaw BJ. 2017. Thermodynamic constraints on the amplitude of quantum oscillations. Physical Review B. 95(12), 121106.","chicago":"Shekhter, Arkady, Kimberly A Modic, R. D. McDonald, and B. J. Ramshaw. “Thermodynamic Constraints on the Amplitude of Quantum Oscillations.” <i>Physical Review B</i>. APS, 2017. <a href=\"https://doi.org/10.1103/physrevb.95.121106\">https://doi.org/10.1103/physrevb.95.121106</a>.","mla":"Shekhter, Arkady, et al. “Thermodynamic Constraints on the Amplitude of Quantum Oscillations.” <i>Physical Review B</i>, vol. 95, no. 12, 121106, APS, 2017, doi:<a href=\"https://doi.org/10.1103/physrevb.95.121106\">10.1103/physrevb.95.121106</a>.","short":"A. Shekhter, K.A. Modic, R.D. McDonald, B.J. Ramshaw, Physical Review B 95 (2017).","apa":"Shekhter, A., Modic, K. A., McDonald, R. D., &#38; Ramshaw, B. J. (2017). Thermodynamic constraints on the amplitude of quantum oscillations. <i>Physical Review B</i>. APS. <a href=\"https://doi.org/10.1103/physrevb.95.121106\">https://doi.org/10.1103/physrevb.95.121106</a>","ama":"Shekhter A, Modic KA, McDonald RD, Ramshaw BJ. Thermodynamic constraints on the amplitude of quantum oscillations. <i>Physical Review B</i>. 2017;95(12). doi:<a href=\"https://doi.org/10.1103/physrevb.95.121106\">10.1103/physrevb.95.121106</a>"},"title":"Thermodynamic constraints on the amplitude of quantum oscillations","publication":"Physical Review B","quality_controlled":"1","intvolume":"        95","status":"public","volume":95,"publication_status":"published","publisher":"APS","month":"03","extern":"1","article_number":"121106","abstract":[{"text":"Magneto-quantum oscillation experiments in high-temperature superconductors show a strong thermally induced suppression of the oscillation amplitude approaching the critical dopings [B. J. Ramshaw et al., Science 348, 317 (2014); H. Shishido et al., Phys. Rev. Lett. 104, 057008 (2010); P. Walmsley et al., Phys. Rev. Lett. 110, 257002 (2013)]—in support of a quantum-critical origin of their phase diagrams. We suggest that, in addition to a thermodynamic mass enhancement, these experiments may directly indicate the increasing role of quantum fluctuations that suppress the quantum oscillation amplitude through inelastic scattering. We show that the traditional theoretical approaches beyond Lifshitz-Kosevich to calculate the oscillation amplitude in correlated metals result in a contradiction with the third law of thermodynamics and suggest a way to rectify this problem.","lang":"eng"}],"_id":"7065","date_created":"2019-11-19T13:12:27Z","date_published":"2017-03-27T00:00:00Z","article_processing_charge":"No","issue":"12"},{"type":"journal_article","author":[{"last_name":"Zhu","full_name":"Zhu, Z.","first_name":"Z."},{"full_name":"McDonald, R. D.","first_name":"R. D.","last_name":"McDonald"},{"first_name":"A.","full_name":"Shekhter, A.","last_name":"Shekhter"},{"full_name":"Ramshaw, B. J.","first_name":"B. J.","last_name":"Ramshaw"},{"last_name":"Modic","first_name":"Kimberly A","full_name":"Modic, Kimberly A","id":"13C26AC0-EB69-11E9-87C6-5F3BE6697425","orcid":"0000-0001-9760-3147"},{"last_name":"Balakirev","first_name":"F. F.","full_name":"Balakirev, F. F."},{"last_name":"Harrison","full_name":"Harrison, N.","first_name":"N."}],"day":"04","title":"Magnetic field tuning of an excitonic insulator between the weak and strong coupling regimes in quantum limit graphite","citation":{"chicago":"Zhu, Z., R. D. McDonald, A. Shekhter, B. J. Ramshaw, Kimberly A Modic, F. F. Balakirev, and N. Harrison. “Magnetic Field Tuning of an Excitonic Insulator between the Weak and Strong Coupling Regimes in Quantum Limit Graphite.” <i>Scientific Reports</i>. Springer Nature, 2017. <a href=\"https://doi.org/10.1038/s41598-017-01693-5\">https://doi.org/10.1038/s41598-017-01693-5</a>.","ista":"Zhu Z, McDonald RD, Shekhter A, Ramshaw BJ, Modic KA, Balakirev FF, Harrison N. 2017. Magnetic field tuning of an excitonic insulator between the weak and strong coupling regimes in quantum limit graphite. Scientific Reports. 7, 1733.","ieee":"Z. Zhu <i>et al.</i>, “Magnetic field tuning of an excitonic insulator between the weak and strong coupling regimes in quantum limit graphite,” <i>Scientific Reports</i>, vol. 7. Springer Nature, 2017.","mla":"Zhu, Z., et al. “Magnetic Field Tuning of an Excitonic Insulator between the Weak and Strong Coupling Regimes in Quantum Limit Graphite.” <i>Scientific Reports</i>, vol. 7, 1733, Springer Nature, 2017, doi:<a href=\"https://doi.org/10.1038/s41598-017-01693-5\">10.1038/s41598-017-01693-5</a>.","short":"Z. Zhu, R.D. McDonald, A. Shekhter, B.J. Ramshaw, K.A. Modic, F.F. Balakirev, N. Harrison, Scientific Reports 7 (2017).","ama":"Zhu Z, McDonald RD, Shekhter A, et al. Magnetic field tuning of an excitonic insulator between the weak and strong coupling regimes in quantum limit graphite. <i>Scientific Reports</i>. 2017;7. doi:<a href=\"https://doi.org/10.1038/s41598-017-01693-5\">10.1038/s41598-017-01693-5</a>","apa":"Zhu, Z., McDonald, R. D., Shekhter, A., Ramshaw, B. J., Modic, K. A., Balakirev, F. F., &#38; Harrison, N. (2017). Magnetic field tuning of an excitonic insulator between the weak and strong coupling regimes in quantum limit graphite. <i>Scientific Reports</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41598-017-01693-5\">https://doi.org/10.1038/s41598-017-01693-5</a>"},"ddc":["530"],"doi":"10.1038/s41598-017-01693-5","language":[{"iso":"eng"}],"date_created":"2019-11-19T13:17:46Z","extern":"1","month":"05","status":"public","intvolume":"         7","quality_controlled":"1","publication":"Scientific Reports","publisher":"Springer Nature","year":"2017","has_accepted_license":"1","oa_version":"Published Version","article_type":"original","publication_identifier":{"issn":["2045-2322"]},"date_updated":"2021-01-12T08:11:40Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","_id":"7066","date_published":"2017-05-04T00:00:00Z","abstract":[{"text":"The excitonic insulator phase has long been predicted to form in proximity to a band gap opening in the underlying band structure. The character of the pairing is conjectured to crossover from weak (BCS-like) to strong coupling (BEC-like) as the underlying band structure is tuned from the metallic to the insulating side of the gap opening. Here we report the high-magnetic field phase diagram of graphite to exhibit just such a crossover. By way of comprehensive angle-resolved magnetoresistance measurements, we demonstrate that the underlying band gap opening occurs inside the magnetic field-induced phase, paving the way for a systematic study of the BCS-BEC-like crossover by means of conventional condensed matter probes.","lang":"eng"}],"article_number":"1733","file":[{"file_size":1571567,"creator":"dernst","file_name":"2017_ScientificReports_Zhu.pdf","checksum":"801f80b04ecd1ead95c8ab9827cbe067","access_level":"open_access","date_updated":"2020-07-14T12:47:48Z","relation":"main_file","file_id":"7111","content_type":"application/pdf","date_created":"2019-11-26T11:58:58Z"}],"article_processing_charge":"No","volume":7,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)"},"file_date_updated":"2020-07-14T12:47:48Z","oa":1,"publication_status":"published"},{"issue":"1","article_processing_charge":"No","abstract":[{"text":"Broken fourfold rotational (C4) symmetry is observed in the experimental properties of several classes of unconventional superconductors. It has been proposed that this symmetry breaking is important for superconducting pairing in these materials, but in the high-Tc cuprates this broken symmetry has never been observed on the Fermi surface. Here we report a pronounced anisotropy in the angle dependence of the interlayer magnetoresistance of the underdoped high transition temperature (high-Tc) superconductor YBa2Cu3O6.58, directly revealing broken C4 symmetry on the Fermi surface. Moreover, we demonstrate that this Fermi surface has C2 symmetry of the type produced by a uniaxial or anisotropic density-wave phase. This establishes the central role of C4 symmetry breaking in the Fermi surface reconstruction of YBa2Cu3O6+δ , and suggests a striking degree of universality among unconventional superconductors.","lang":"eng"}],"_id":"7067","date_published":"2017-02-13T00:00:00Z","file":[{"date_created":"2019-11-26T12:57:11Z","file_id":"7115","relation":"main_file","content_type":"application/pdf","checksum":"433a26a7e14206e139f3fec2c8ee8623","access_level":"open_access","date_updated":"2020-07-14T12:47:48Z","file_size":1383236,"creator":"dernst","file_name":"2017_NPJ_Ramshaw.pdf"}],"article_number":"8","oa":1,"publication_status":"published","volume":2,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)"},"file_date_updated":"2020-07-14T12:47:48Z","oa_version":"Published Version","year":"2017","has_accepted_license":"1","article_type":"original","publication_identifier":{"issn":["2397-4648"]},"date_updated":"2021-01-12T08:11:40Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2019-11-19T13:18:30Z","extern":"1","month":"02","publisher":"Springer Nature","status":"public","intvolume":"         2","quality_controlled":"1","publication":"npj Quantum Materials","title":"Broken rotational symmetry on the Fermi surface of a high-Tc superconductor","citation":{"mla":"Ramshaw, B. J., et al. “Broken Rotational Symmetry on the Fermi Surface of a High-Tc Superconductor.” <i>Npj Quantum Materials</i>, vol. 2, no. 1, 8, Springer Nature, 2017, doi:<a href=\"https://doi.org/10.1038/s41535-017-0013-z\">10.1038/s41535-017-0013-z</a>.","chicago":"Ramshaw, B. J., N. Harrison, S. E. Sebastian, S. Ghannadzadeh, Kimberly A Modic, D. A. Bonn, W. N. Hardy, Ruixing Liang, and P. A. Goddard. “Broken Rotational Symmetry on the Fermi Surface of a High-Tc Superconductor.” <i>Npj Quantum Materials</i>. Springer Nature, 2017. <a href=\"https://doi.org/10.1038/s41535-017-0013-z\">https://doi.org/10.1038/s41535-017-0013-z</a>.","ieee":"B. J. Ramshaw <i>et al.</i>, “Broken rotational symmetry on the Fermi surface of a high-Tc superconductor,” <i>npj Quantum Materials</i>, vol. 2, no. 1. Springer Nature, 2017.","ista":"Ramshaw BJ, Harrison N, Sebastian SE, Ghannadzadeh S, Modic KA, Bonn DA, Hardy WN, Liang R, Goddard PA. 2017. Broken rotational symmetry on the Fermi surface of a high-Tc superconductor. npj Quantum Materials. 2(1), 8.","ama":"Ramshaw BJ, Harrison N, Sebastian SE, et al. Broken rotational symmetry on the Fermi surface of a high-Tc superconductor. <i>npj Quantum Materials</i>. 2017;2(1). doi:<a href=\"https://doi.org/10.1038/s41535-017-0013-z\">10.1038/s41535-017-0013-z</a>","apa":"Ramshaw, B. J., Harrison, N., Sebastian, S. E., Ghannadzadeh, S., Modic, K. A., Bonn, D. A., … Goddard, P. A. (2017). Broken rotational symmetry on the Fermi surface of a high-Tc superconductor. <i>Npj Quantum Materials</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41535-017-0013-z\">https://doi.org/10.1038/s41535-017-0013-z</a>","short":"B.J. Ramshaw, N. Harrison, S.E. Sebastian, S. Ghannadzadeh, K.A. Modic, D.A. Bonn, W.N. Hardy, R. Liang, P.A. Goddard, Npj Quantum Materials 2 (2017)."},"type":"journal_article","author":[{"last_name":"Ramshaw","first_name":"B. J.","full_name":"Ramshaw, B. J."},{"last_name":"Harrison","full_name":"Harrison, N.","first_name":"N."},{"first_name":"S. E.","full_name":"Sebastian, S. E.","last_name":"Sebastian"},{"last_name":"Ghannadzadeh","full_name":"Ghannadzadeh, S.","first_name":"S."},{"last_name":"Modic","full_name":"Modic, Kimberly A","first_name":"Kimberly A","id":"13C26AC0-EB69-11E9-87C6-5F3BE6697425","orcid":"0000-0001-9760-3147"},{"first_name":"D. A.","full_name":"Bonn, D. A.","last_name":"Bonn"},{"first_name":"W. N.","full_name":"Hardy, W. N.","last_name":"Hardy"},{"first_name":"Ruixing","full_name":"Liang, Ruixing","last_name":"Liang"},{"last_name":"Goddard","first_name":"P. A.","full_name":"Goddard, P. A."}],"day":"13","ddc":["530"],"doi":"10.1038/s41535-017-0013-z","language":[{"iso":"eng"}]},{"publisher":"Wiley-Blackwell","publication":"Bulletin of the London Mathematical Society","department":[{"_id":"HeEd"}],"quality_controlled":"1","status":"public","intvolume":"        49","page":"690 - 693","month":"08","date_created":"2018-12-11T11:48:02Z","project":[{"call_identifier":"FP7","_id":"25681D80-B435-11E9-9278-68D0E5697425","grant_number":"291734","name":"International IST Postdoc Fellowship Programme"}],"language":[{"iso":"eng"}],"doi":"10.1112/blms.12062","citation":{"apa":"Akopyan, A., &#38; Karasev, R. (2017). A tight estimate for the waist of the ball . <i>Bulletin of the London Mathematical Society</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1112/blms.12062\">https://doi.org/10.1112/blms.12062</a>","ama":"Akopyan A, Karasev R. A tight estimate for the waist of the ball . <i>Bulletin of the London Mathematical Society</i>. 2017;49(4):690-693. doi:<a href=\"https://doi.org/10.1112/blms.12062\">10.1112/blms.12062</a>","short":"A. Akopyan, R. Karasev, Bulletin of the London Mathematical Society 49 (2017) 690–693.","mla":"Akopyan, Arseniy, and Roman Karasev. “A Tight Estimate for the Waist of the Ball .” <i>Bulletin of the London Mathematical Society</i>, vol. 49, no. 4, Wiley-Blackwell, 2017, pp. 690–93, doi:<a href=\"https://doi.org/10.1112/blms.12062\">10.1112/blms.12062</a>.","ista":"Akopyan A, Karasev R. 2017. A tight estimate for the waist of the ball . Bulletin of the London Mathematical Society. 49(4), 690–693.","ieee":"A. Akopyan and R. Karasev, “A tight estimate for the waist of the ball ,” <i>Bulletin of the London Mathematical Society</i>, vol. 49, no. 4. Wiley-Blackwell, pp. 690–693, 2017.","chicago":"Akopyan, Arseniy, and Roman Karasev. “A Tight Estimate for the Waist of the Ball .” <i>Bulletin of the London Mathematical Society</i>. Wiley-Blackwell, 2017. <a href=\"https://doi.org/10.1112/blms.12062\">https://doi.org/10.1112/blms.12062</a>."},"ec_funded":1,"title":"A tight estimate for the waist of the ball ","day":"01","type":"journal_article","author":[{"first_name":"Arseniy","full_name":"Akopyan, Arseniy","last_name":"Akopyan","orcid":"0000-0002-2548-617X","id":"430D2C90-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Karasev","first_name":"Roman","full_name":"Karasev, Roman"}],"publication_status":"published","main_file_link":[{"url":"https://arxiv.org/abs/1608.06279","open_access":"1"}],"oa":1,"volume":49,"issue":"4","_id":"707","abstract":[{"text":"We answer a question of M. Gromov on the waist of the unit ball.","lang":"eng"}],"date_published":"2017-08-01T00:00:00Z","scopus_import":1,"date_updated":"2021-01-12T08:11:41Z","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"issn":["00246093"]},"publist_id":"6982","year":"2017","oa_version":"Preprint"},{"title":"Different patterns of neuronal activity trigger distinct responses of oligodendrocyte precursor cells in the corpus callosum","citation":{"ieee":"B. Nagy, A. Hovhannisyan, R. Barzan, T. Chen, and M. Kukley, “Different patterns of neuronal activity trigger distinct responses of oligodendrocyte precursor cells in the corpus callosum,” <i>PLoS Biology</i>, vol. 15, no. 8. Public Library of Science, 2017.","ista":"Nagy B, Hovhannisyan A, Barzan R, Chen T, Kukley M. 2017. Different patterns of neuronal activity trigger distinct responses of oligodendrocyte precursor cells in the corpus callosum. PLoS Biology. 15(8), e2001993.","chicago":"Nagy, Balint, Anahit Hovhannisyan, Ruxandra Barzan, Ting Chen, and Maria Kukley. “Different Patterns of Neuronal Activity Trigger Distinct Responses of Oligodendrocyte Precursor Cells in the Corpus Callosum.” <i>PLoS Biology</i>. Public Library of Science, 2017. <a href=\"https://doi.org/10.1371/journal.pbio.2001993\">https://doi.org/10.1371/journal.pbio.2001993</a>.","mla":"Nagy, Balint, et al. “Different Patterns of Neuronal Activity Trigger Distinct Responses of Oligodendrocyte Precursor Cells in the Corpus Callosum.” <i>PLoS Biology</i>, vol. 15, no. 8, e2001993, Public Library of Science, 2017, doi:<a href=\"https://doi.org/10.1371/journal.pbio.2001993\">10.1371/journal.pbio.2001993</a>.","short":"B. Nagy, A. Hovhannisyan, R. Barzan, T. Chen, M. Kukley, PLoS Biology 15 (2017).","apa":"Nagy, B., Hovhannisyan, A., Barzan, R., Chen, T., &#38; Kukley, M. (2017). Different patterns of neuronal activity trigger distinct responses of oligodendrocyte precursor cells in the corpus callosum. <i>PLoS Biology</i>. Public Library of Science. <a href=\"https://doi.org/10.1371/journal.pbio.2001993\">https://doi.org/10.1371/journal.pbio.2001993</a>","ama":"Nagy B, Hovhannisyan A, Barzan R, Chen T, Kukley M. Different patterns of neuronal activity trigger distinct responses of oligodendrocyte precursor cells in the corpus callosum. <i>PLoS Biology</i>. 2017;15(8). doi:<a href=\"https://doi.org/10.1371/journal.pbio.2001993\">10.1371/journal.pbio.2001993</a>"},"type":"journal_article","author":[{"first_name":"Balint","full_name":"Nagy, Balint","last_name":"Nagy","orcid":"0000-0002-4002-4686","id":"30F830CE-02D1-11E9-9BAA-DAF4881429F2"},{"first_name":"Anahit","full_name":"Hovhannisyan, Anahit","last_name":"Hovhannisyan"},{"full_name":"Barzan, Ruxandra","first_name":"Ruxandra","last_name":"Barzan"},{"first_name":"Ting","full_name":"Chen, Ting","last_name":"Chen"},{"last_name":"Kukley","first_name":"Maria","full_name":"Kukley, Maria"}],"day":"22","ddc":["576","610"],"doi":"10.1371/journal.pbio.2001993","language":[{"iso":"eng"}],"date_created":"2018-12-11T11:48:03Z","month":"08","publisher":"Public Library of Science","status":"public","intvolume":"        15","department":[{"_id":"SaSi"}],"quality_controlled":"1","publication":"PLoS Biology","oa_version":"Published Version","has_accepted_license":"1","year":"2017","publist_id":"6983","publication_identifier":{"issn":["15449173"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2021-01-12T08:11:45Z","scopus_import":1,"issue":"8","_id":"708","date_published":"2017-08-22T00:00:00Z","abstract":[{"text":"In the developing and adult brain, oligodendrocyte precursor cells (OPCs) are influenced by neuronal activity: they are involved in synaptic signaling with neurons, and their proliferation and differentiation into myelinating glia can be altered by transient changes in neuronal firing. An important question that has been unanswered is whether OPCs can discriminate different patterns of neuronal activity and respond to them in a distinct way. Here, we demonstrate in brain slices that the pattern of neuronal activity determines the functional changes triggered at synapses between axons and OPCs. Furthermore, we show that stimulation of the corpus callosum at different frequencies in vivo affects proliferation and differentiation of OPCs in a dissimilar way. Our findings suggest that neurons do not influence OPCs in “all-or-none” fashion but use their firing pattern to tune the response and behavior of these nonneuronal cells.","lang":"eng"}],"article_number":"e2001993","file":[{"content_type":"application/pdf","relation":"main_file","file_id":"5156","date_created":"2018-12-12T10:15:35Z","file_name":"IST-2017-889-v1+1_journal.pbio.2001993.pdf","file_size":18155365,"creator":"system","date_updated":"2020-07-14T12:47:49Z","access_level":"open_access","checksum":"0c974f430682dc832ea7b27ab5a93124"}],"oa":1,"publication_status":"published","volume":15,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)"},"pubrep_id":"889","file_date_updated":"2020-07-14T12:47:49Z"},{"publication":"Cell Biology International","quality_controlled":"1","department":[{"_id":"RySh"}],"intvolume":"        41","status":"public","volume":41,"publisher":"Wiley-Blackwell","publication_status":"published","month":"08","date_published":"2017-08-01T00:00:00Z","_id":"709","date_created":"2018-12-11T11:48:04Z","abstract":[{"lang":"eng","text":"Adipose tissues play key roles in energy homeostasis. Brown adipocytes and beige adipocytes in white adipose tissue (WAT) share the similar characters of thermogenesis, both of them could be potential targets for obesity management. Several thermo-sensitive transient receptor potential channels (thermoTRPs) are shown to be involved in adipocyte biology. However, the expression pattern of thermoTRPs in adipose tissues from obese mice is still unknown. The mRNA expression of thermoTRPs in subcutaneous WAT (sWAT) and interscapular brown adipose tissue (iBAT) from lean and obese mice were measured using reverse transcriptase-quantitative PCRs (RT-qPCR). The results demonstrated that all 10 thermoTRPs are expressed in both iBAT and sWAT, and without significant difference in the mRNA expression level of thermoTRPs between these two tissues. Moreover, Trpv1 and Trpv3 mRNA expression levels in both iBAT and sWAT were significantly decreased in high fat diet (HFD)-induced obese mice and db/db (leptin receptor deficient) mice. Trpm2 mRNA expression level was significantly decreased only in sWAT from HFD-induced obese mice and db/db mice. On the other hand, Trpv2 and Trpv4 mRNA expression levels in iBAT and sWAT were significantly increased in HFD-induced obese mice and db/db mice. Taken together, we conclude that all 10 thermoTRPs are expressed in iBAT and sWAT. And several thermoTRPs differentially expressed in adipose tissues from HFD-induced obese mice and db/db mice, suggesting a potential involvement in anti-obesity regulations."}],"page":"908 - 913","issue":"8","scopus_import":1,"date_updated":"2021-01-12T08:11:47Z","language":[{"iso":"eng"}],"user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"issn":["10656995"]},"doi":"10.1002/cbin.10783","day":"01","publist_id":"6981","author":[{"full_name":"Sun, Wuping","first_name":"Wuping","last_name":"Sun"},{"last_name":"Li","full_name":"Li, Chen","first_name":"Chen"},{"first_name":"Yonghong","full_name":"Zhang, Yonghong","last_name":"Zhang"},{"last_name":"Jiang","full_name":"Jiang, Changyu","first_name":"Changyu"},{"id":"34009CFA-F248-11E8-B48F-1D18A9856A87","last_name":"Zhai","first_name":"Ming-Zhu","full_name":"Zhai, Ming-Zhu"},{"last_name":"Zhou","first_name":"Qian","full_name":"Zhou, Qian"},{"first_name":"Lizu","full_name":"Xiao, Lizu","last_name":"Xiao"},{"last_name":"Deng","first_name":"Qiwen","full_name":"Deng, Qiwen"}],"type":"journal_article","oa_version":"None","year":"2017","citation":{"short":"W. Sun, C. Li, Y. Zhang, C. Jiang, M.-Z. Zhai, Q. Zhou, L. Xiao, Q. Deng, Cell Biology International 41 (2017) 908–913.","apa":"Sun, W., Li, C., Zhang, Y., Jiang, C., Zhai, M.-Z., Zhou, Q., … Deng, Q. (2017). Gene expression changes of thermo sensitive transient receptor potential channels in obese mice. <i>Cell Biology International</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1002/cbin.10783\">https://doi.org/10.1002/cbin.10783</a>","ama":"Sun W, Li C, Zhang Y, et al. Gene expression changes of thermo sensitive transient receptor potential channels in obese mice. <i>Cell Biology International</i>. 2017;41(8):908-913. doi:<a href=\"https://doi.org/10.1002/cbin.10783\">10.1002/cbin.10783</a>","ista":"Sun W, Li C, Zhang Y, Jiang C, Zhai M-Z, Zhou Q, Xiao L, Deng Q. 2017. Gene expression changes of thermo sensitive transient receptor potential channels in obese mice. Cell Biology International. 41(8), 908–913.","ieee":"W. Sun <i>et al.</i>, “Gene expression changes of thermo sensitive transient receptor potential channels in obese mice,” <i>Cell Biology International</i>, vol. 41, no. 8. Wiley-Blackwell, pp. 908–913, 2017.","chicago":"Sun, Wuping, Chen Li, Yonghong Zhang, Changyu Jiang, Ming-Zhu Zhai, Qian Zhou, Lizu Xiao, and Qiwen Deng. “Gene Expression Changes of Thermo Sensitive Transient Receptor Potential Channels in Obese Mice.” <i>Cell Biology International</i>. Wiley-Blackwell, 2017. <a href=\"https://doi.org/10.1002/cbin.10783\">https://doi.org/10.1002/cbin.10783</a>.","mla":"Sun, Wuping, et al. “Gene Expression Changes of Thermo Sensitive Transient Receptor Potential Channels in Obese Mice.” <i>Cell Biology International</i>, vol. 41, no. 8, Wiley-Blackwell, 2017, pp. 908–13, doi:<a href=\"https://doi.org/10.1002/cbin.10783\">10.1002/cbin.10783</a>."},"title":"Gene expression changes of thermo sensitive transient receptor potential channels in obese mice"},{"status":"public","intvolume":"        81","department":[{"_id":"KrPi"}],"quality_controlled":"1","publisher":"Schloss Dagstuhl - Leibniz-Zentrum für Informatik","date_created":"2018-12-11T11:48:04Z","month":"08","doi":"10.4230/LIPIcs.APPROX-RANDOM.2017.20","ddc":["005","600"],"language":[{"iso":"eng"}],"project":[{"grant_number":"682815","name":"Teaching Old Crypto New Tricks","call_identifier":"H2020","_id":"258AA5B2-B435-11E9-9278-68D0E5697425"}],"author":[{"first_name":"Maciej","full_name":"Obremski, Maciej","last_name":"Obremski"},{"last_name":"Skórski","first_name":"Maciej","full_name":"Skórski, Maciej","id":"EC09FA6A-02D0-11E9-8223-86B7C91467DD"}],"type":"conference","alternative_title":["LIPIcs"],"day":"01","title":"Renyi entropy estimation revisited","conference":{"end_date":"2017-08-18","start_date":"2017-08-18","name":"20th International Workshop on Approximation Algorithms for Combinatorial Optimization Problems, APPROX","location":"Berkeley, USA"},"citation":{"ista":"Obremski M, Skórski M. 2017. Renyi entropy estimation revisited. 20th International Workshop on Approximation Algorithms for Combinatorial Optimization Problems, APPROX, LIPIcs, vol. 81, 20.","ieee":"M. Obremski and M. Skórski, “Renyi entropy estimation revisited,” presented at the 20th International Workshop on Approximation Algorithms for Combinatorial Optimization Problems, APPROX, Berkeley, USA, 2017, vol. 81.","chicago":"Obremski, Maciej, and Maciej Skórski. “Renyi Entropy Estimation Revisited,” Vol. 81. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2017. <a href=\"https://doi.org/10.4230/LIPIcs.APPROX-RANDOM.2017.20\">https://doi.org/10.4230/LIPIcs.APPROX-RANDOM.2017.20</a>.","mla":"Obremski, Maciej, and Maciej Skórski. <i>Renyi Entropy Estimation Revisited</i>. Vol. 81, 20, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2017, doi:<a href=\"https://doi.org/10.4230/LIPIcs.APPROX-RANDOM.2017.20\">10.4230/LIPIcs.APPROX-RANDOM.2017.20</a>.","short":"M. Obremski, M. Skórski, in:, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2017.","apa":"Obremski, M., &#38; Skórski, M. (2017). Renyi entropy estimation revisited (Vol. 81). Presented at the 20th International Workshop on Approximation Algorithms for Combinatorial Optimization Problems, APPROX, Berkeley, USA: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. <a href=\"https://doi.org/10.4230/LIPIcs.APPROX-RANDOM.2017.20\">https://doi.org/10.4230/LIPIcs.APPROX-RANDOM.2017.20</a>","ama":"Obremski M, Skórski M. Renyi entropy estimation revisited. In: Vol 81. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2017. doi:<a href=\"https://doi.org/10.4230/LIPIcs.APPROX-RANDOM.2017.20\">10.4230/LIPIcs.APPROX-RANDOM.2017.20</a>"},"ec_funded":1,"pubrep_id":"888","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)"},"volume":81,"file_date_updated":"2020-07-14T12:47:49Z","oa":1,"publication_status":"published","date_published":"2017-08-01T00:00:00Z","_id":"710","abstract":[{"lang":"eng","text":"We revisit the problem of estimating entropy of discrete distributions from independent samples, studied recently by Acharya, Orlitsky, Suresh and Tyagi (SODA 2015), improving their upper and lower bounds on the necessary sample size n. For estimating Renyi entropy of order alpha, up to constant accuracy and error probability, we show the following * Upper bounds n = O(1) 2^{(1-1/alpha)H_alpha} for integer alpha&gt;1, as the worst case over distributions with Renyi entropy equal to H_alpha. * Lower bounds n = Omega(1) K^{1-1/alpha} for any real alpha&gt;1, with the constant being an inverse polynomial of the accuracy, as the worst case over all distributions on K elements. Our upper bounds essentially replace the alphabet size by a factor exponential in the entropy, which offers improvements especially in low or medium entropy regimes (interesting for example in anomaly detection). As for the lower bounds, our proof explicitly shows how the complexity depends on both alphabet and accuracy, partially solving the open problem posted in previous works. The argument for upper bounds derives a clean identity for the variance of falling-power sum of a multinomial distribution. Our approach for lower bounds utilizes convex optimization to find a distribution with possibly worse estimation performance, and may be of independent interest as a tool to work with Le Cam’s two point method. "}],"article_number":"20","file":[{"file_id":"4991","relation":"main_file","content_type":"application/pdf","date_created":"2018-12-12T10:13:10Z","file_size":604813,"creator":"system","file_name":"IST-2017-888-v1+1_LIPIcs-APPROX-RANDOM-2017-20.pdf","access_level":"open_access","date_updated":"2020-07-14T12:47:49Z","checksum":"89225c7dcec2c93838458c9102858985"}],"publication_identifier":{"issn":["18688969"]},"scopus_import":1,"date_updated":"2021-01-12T08:11:50Z","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","year":"2017","oa_version":"Published Version","has_accepted_license":"1","publist_id":"6979"}]