@article{12610,
  abstract     = {The hydrological systems of heavily-downwasted debris-covered glaciers differ from those of clean-ice glaciers due to the hummocky surface and debris mantle of such glaciers, leading to a relatively limited understanding of drainage pathways. Supraglacial ponds represent sinks within the discontinuous supraglacial drainage system, and occasionally drain englacially. To assess pond dynamics, we made pond water level measurements on Lirung Glacier, Nepal, during May and October of 2013 and 2014. Simultaneously, aerial, satellite, and terrestrial orthoimages and digital elevation models were obtained, providing snapshots of the ponds and their surroundings. We performed a DEM-based analysis of the glacier's closed surface catchments to identify surface drainage pathways and englacial drainage points, and compared this to field observations of surface and near-surface water flow. The total ponded area was higher in the pre-monsoon than post-monsoon, with individual ponds filling and draining seasonally associated with the surface exposure of englacial conduit segments. We recorded four pond drainage events, all of which occurred gradually (duration of weeks), observed diurnal fluctuations indicative of varying water supply and outflow discharge, and we documented instances of interaction between distant ponds. The DEM drainage analysis identified numerous sinks >3 m in depth across the glacier surface, few of which exhibited ponds (23%), while the field survey highlighted instances of surface water only explicable via englacial routes. Taken together, our observations provide evidence for widespread supraglacial-englacial connectivity of meltwater drainage paths. Results suggest that successive englacial conduit collapse events, themselves likely driven by supraglacial pond drainage, cause the glacier surface drainage system to evolve into a configuration following relict englacial conduit systems. Within this system, ponds form in depressions of reduced drainage efficiency and link the supraglacial and englacial drainage networks.},
  author       = {Miles, Evan S. and Steiner, Jakob and Willis, Ian and Buri, Pascal and Immerzeel, Walter W. and Chesnokova, Anna and Pellicciotti, Francesca},
  issn         = {2296-6463},
  journal      = {Frontiers in Earth Science},
  keywords     = {General Earth and Planetary Sciences},
  publisher    = {Frontiers Media},
  title        = {{Pond dynamics and supraglacial-englacial connectivity on debris-covered Lirung Glacier, Nepal}},
  doi          = {10.3389/feart.2017.00069},
  volume       = {5},
  year         = {2017},
}

@article{12611,
  abstract     = {We investigate the energy balance and ablation regimes of glaciers in high-elevation, dry environments using glaciometeorological data collected on six glaciers in the semiarid Andes of North-Central Chile (29–34°S, 3127–5324 m). We use a point-scale physically based energy balance (EB) model and an enhanced Temperature-Index (ETI) model that calculates melt rates only as a function of air temperature and net shortwave radiation. At all sites, the largest energy inputs are net shortwave and incoming longwave radiation, which are controlled by surface albedo and elevation, respectively. Turbulent fluxes cancel each other out at the lower sites, but as elevation increases, cold, dry and wind-exposed conditions increase the magnitude of negative latent heat fluxes, associated with large surface sublimation rates. In midsummer (January), ablation rates vary from 67.9 mm w.e. d−1 at the lowest site (∼100% corresponding to melt), to 2.3 mm w.e. d−1 at the highest site (>85% corresponding to surface sublimation). At low-elevation, low-albedo, melt-dominated sites, the ETI model correctly reproduces melt using a large range of possible parameters, but both the performance and parameter transferability decrease with elevation for two main reasons: (i) the air temperature threshold approach for melt onset does not capture the diurnal variability of melt in cold and strong irradiated environments and (ii) energy losses decrease the correlation between melt and net shortwave radiation. We summarize our results by means of an elevation profile of ablation components that can be used as reference in future studies of glacier ablation in the semiarid Andes.},
  author       = {Ayala, A. and Pellicciotti, Francesca and MacDonell, S. and McPhee, J. and Burlando, P.},
  issn         = {0043-1397},
  journal      = {Water Resources Research},
  keywords     = {Water Science and Technology},
  number       = {7},
  pages        = {5601--5625},
  publisher    = {American Geophysical Union},
  title        = {{Patterns of glacier ablation across North-Central Chile: Identifying the limits of empirical melt models under sublimation-favorable conditions}},
  doi          = {10.1002/2016wr020126},
  volume       = {53},
  year         = {2017},
}

@article{12612,
  abstract     = {Supraglacial ponds play a key role in absorbing atmospheric energy and directing it to the ice of debris-covered glaciers, but the spatial and temporal distribution of these features is not well documented. We analyse 172 Landsat TM/ETM+ scenes for the period 1999–2013 to identify thawed supraglacial ponds for the debris-covered tongues of five glaciers in the Langtang Valley of Nepal. We apply an advanced atmospheric correction routine (Landcor/6S) and use band ratio and image morphological techniques to identify ponds and validate our results with 2.5 m Cartosat-1 observations. We then characterize the spatial, seasonal and interannual patterns of ponds. We find high variability in pond incidence between glaciers (May–October means of 0.08–1.69% of debris area), with ponds most frequent in zones of low surface gradient and velocity. The ponds show pronounced seasonality, appearing in the pre-monsoon as snow melts, peaking at the monsoon onset at 2% of debris-covered area, then declining in the post-monsoon as ponds drain or freeze. Ponds are highly recurrent and persistent, with 40.5% of pond locations occurring for multiple years. Rather than a trend in pond cover over the study period, we find high interannual variability for each glacier after controlling for seasonality.},
  author       = {MILES, EVAN S. and WILLIS, IAN C. and ARNOLD, NEIL S. and STEINER, JAKOB and Pellicciotti, Francesca},
  issn         = {1727-5652},
  journal      = {Journal of Glaciology},
  keywords     = {Earth-Surface Processes},
  number       = {237},
  pages        = {88--105},
  publisher    = {Cambridge University Press},
  title        = {{Spatial, seasonal and interannual variability of supraglacial ponds in the Langtang Valley of Nepal, 1999–2013}},
  doi          = {10.1017/jog.2016.120},
  volume       = {63},
  year         = {2017},
}

@inproceedings{12905,
  author       = {Schlögl, Alois and Kiss, Janos},
  booktitle    = {AHPC17 – Austrian HPC Meeting 2017},
  location     = {Grundlsee, Austria},
  pages        = {28},
  publisher    = {FSP Scientific Computing},
  title        = {{Scientific Computing at IST Austria}},
  year         = {2017},
}

@article{1294,
  abstract     = {We study controller synthesis problems for finite-state Markov decision processes, where the objective is to optimize the expected mean-payoff performance and stability (also known as variability in the literature). We argue that the basic notion of expressing the stability using the statistical variance of the mean payoff is sometimes insufficient, and propose an alternative definition. We show that a strategy ensuring both the expected mean payoff and the variance below given bounds requires randomization and memory, under both the above definitions. We then show that the problem of finding such a strategy can be expressed as a set of constraints.},
  author       = {Brázdil, Tomáš and Chatterjee, Krishnendu and Forejt, Vojtěch and Kučera, Antonín},
  journal      = {Journal of Computer and System Sciences},
  pages        = {144 -- 170},
  publisher    = {Elsevier},
  title        = {{Trading performance for stability in Markov decision processes}},
  doi          = {10.1016/j.jcss.2016.09.009},
  volume       = {84},
  year         = {2017},
}

@misc{9707,
  abstract     = {Branching morphogenesis of the epithelial ureteric bud forms the renal collecting duct system and is critical for normal nephron number, while low nephron number is implicated in hypertension and renal disease. Ureteric bud growth and branching requires GDNF signaling from the surrounding mesenchyme to cells at the ureteric bud tips, via the Ret receptor tyrosine kinase and coreceptor Gfrα1; Ret signaling up-regulates transcription factors Etv4 and Etv5, which are also critical for branching. Despite extensive knowledge of the genetic control of these events, it is not understood, at the cellular level, how renal branching morphogenesis is achieved or how Ret signaling influences epithelial cell behaviors to promote this process. Analysis of chimeric embryos previously suggested a role for Ret signaling in promoting cell rearrangements in the nephric duct, but this method was unsuited to study individual cell behaviors during ureteric bud branching. Here, we use Mosaic Analysis with Double Markers (MADM), combined with organ culture and time-lapse imaging, to trace the movements and divisions of individual ureteric bud tip cells. We first examine wild-type clones and then Ret or Etv4 mutant/wild-type clones in which the mutant and wild-type sister cells are differentially and heritably marked by green and red fluorescent proteins. We find that, in normal kidneys, most individual tip cells behave as self-renewing progenitors, some of whose progeny remain at the tips while others populate the growing UB trunks. In Ret or Etv4 MADM clones, the wild-type cells generated at a UB tip are much more likely to remain at, or move to, the new tips during branching and elongation, while their Ret−/− or Etv4−/− sister cells tend to lag behind and contribute only to the trunks. By tracking successive mitoses in a cell lineage, we find that Ret signaling has little effect on proliferation, in contrast to its effects on cell movement. Our results show that Ret/Etv4 signaling promotes directed cell movements in the ureteric bud tips, and suggest a model in which these cell movements mediate branching morphogenesis.},
  author       = {Riccio, Paul and Cebrián, Christina and Zong, Hui and Hippenmeyer, Simon and Costantini, Frank},
  publisher    = {Dryad},
  title        = {{Data from: Ret and Etv4 promote directed movements of progenitor cells during renal branching morphogenesis}},
  doi          = {10.5061/dryad.pk16b},
  year         = {2017},
}

@misc{9709,
  abstract     = {Across the nervous system, certain population spiking patterns are observed far more frequently than others. A hypothesis about this structure is that these collective activity patterns function as population codewords–collective modes–carrying information distinct from that of any single cell. We investigate this phenomenon in recordings of ∼150 retinal ganglion cells, the retina’s output. We develop a novel statistical model that decomposes the population response into modes; it predicts the distribution of spiking activity in the ganglion cell population with high accuracy. We found that the modes represent localized features of the visual stimulus that are distinct from the features represented by single neurons. Modes form clusters of activity states that are readily discriminated from one another. When we repeated the same visual stimulus, we found that the same mode was robustly elicited. These results suggest that retinal ganglion cells’ collective signaling is endowed with a form of error-correcting code–a principle that may hold in brain areas beyond retina.},
  author       = {Prentice, Jason and Marre, Olivier and Ioffe, Mark and Loback, Adrianna and Tkačik, Gašper and Berry, Michael},
  publisher    = {Dryad},
  title        = {{Data from: Error-robust modes of the retinal population code}},
  doi          = {10.5061/dryad.1f1rc},
  year         = {2017},
}

@misc{9842,
  abstract     = {Mathematica notebooks used to generate figures.},
  author       = {Etheridge, Alison and Barton, Nicholas H},
  publisher    = {Mendeley Data},
  title        = {{Data for: Establishment in a new habitat by polygenic adaptation}},
  doi          = {10.17632/nw68fxzjpm.1},
  year         = {2017},
}

@misc{9844,
  author       = {Nikolic, Nela and Schreiber, Frank and Dal Co, Alma and Kiviet, Daniel and Bergmiller, Tobias and Littmann, Sten and Kuypers, Marcel and Ackermann, Martin},
  publisher    = {Public Library of Science},
  title        = {{Source data for figures and tables}},
  doi          = {10.1371/journal.pgen.1007122.s018},
  year         = {2017},
}

@misc{9845,
  abstract     = {Estimates of 13 C-arabinose and 2 H-glucose uptake from the fractions of heavy isotopes measured	in single cells},
  author       = {Nikolic, Nela and Schreiber, Frank and Dal Co, Alma and Kiviet, Daniel and Bergmiller, Tobias and Littmann, Sten and Kuypers, Marcel and Ackermann, Martin},
  publisher    = {Public Library of Science},
  title        = {{Mathematical model}},
  doi          = {10.1371/journal.pgen.1007122.s017},
  year         = {2017},
}

@misc{9846,
  author       = {Nikolic, Nela and Schreiber, Frank and Dal Co, Alma and Kiviet, Daniel and Bergmiller, Tobias and Littmann, Sten and Kuypers, Marcel and Ackermann, Martin},
  publisher    = {Public Library of Science},
  title        = {{Supplementary methods}},
  doi          = {10.1371/journal.pgen.1007122.s016},
  year         = {2017},
}

@misc{9847,
  abstract     = {information on culture conditions, phage mutagenesis, verification and lysate preparation; Raw data},
  author       = {Pleska, Maros and Guet, Calin C},
  publisher    = {The Royal Society},
  title        = {{Supplementary materials and methods; Full data set from effects of mutations in phage restriction sites during escape from restriction–modification}},
  doi          = {10.6084/m9.figshare.5633917.v1},
  year         = {2017},
}

@misc{9849,
  abstract     = {This text provides additional information about the model, a derivation of the analytic results in Eq (4), and details about simulations of an additional parameter set.},
  author       = {Lukacisinova, Marta and Novak, Sebastian and Paixao, Tiago},
  publisher    = {Public Library of Science},
  title        = {{Modelling and simulation details}},
  doi          = {10.1371/journal.pcbi.1005609.s001},
  year         = {2017},
}

@misc{9850,
  abstract     = {In this text, we discuss how a cost of resistance and the possibility of lethal mutations impact our model.},
  author       = {Lukacisinova, Marta and Novak, Sebastian and Paixao, Tiago},
  publisher    = {Public Library of Science},
  title        = {{Extensions of the model}},
  doi          = {10.1371/journal.pcbi.1005609.s002},
  year         = {2017},
}

@misc{9851,
  abstract     = {Based on the intuitive derivation of the dynamics of SIM allele frequency pM in the main text, we present a heuristic prediction for the long-term SIM allele frequencies with χ > 1 stresses and compare it to numerical simulations.},
  author       = {Lukacisinova, Marta and Novak, Sebastian and Paixao, Tiago},
  publisher    = {Public Library of Science},
  title        = {{Heuristic prediction for multiple stresses}},
  doi          = {10.1371/journal.pcbi.1005609.s003},
  year         = {2017},
}

@misc{9852,
  abstract     = {We show how different combination strategies affect the fraction of individuals that are multi-resistant.},
  author       = {Lukacisinova, Marta and Novak, Sebastian and Paixao, Tiago},
  publisher    = {Public Library of Science},
  title        = {{Resistance frequencies for different combination strategies}},
  doi          = {10.1371/journal.pcbi.1005609.s004},
  year         = {2017},
}

@misc{9853,
  abstract     = {Egg laying rates and infection loads of C. obscurior queens},
  author       = {Giehr, Julia and Grasse, Anna V and Cremer, Sylvia and Heinze, Jürgen and Schrempf, Alexandra},
  publisher    = {The Royal Society},
  title        = {{Raw data from ant queens increase their reproductive efforts after pathogen infection}},
  doi          = {10.6084/m9.figshare.5117788.v1},
  year         = {2017},
}

@misc{9855,
  abstract     = {Includes derivation of optimal estimation algorithm, generalisation to non-poisson noise statistics, correlated input noise, and implementation of in a multi-layer neural network.},
  author       = {Chalk, Matthew J and Masset, Paul and Gutkin, Boris and Denève, Sophie},
  publisher    = {Public Library of Science},
  title        = {{Supplementary appendix}},
  doi          = {10.1371/journal.pcbi.1005582.s001},
  year         = {2017},
}

@misc{9856,
  author       = {Schmidt, Tom and Barton, Nicholas H and Rasic, Gordana and Turley, Andrew and Montgomery, Brian and Iturbe Ormaetxe, Inaki and Cook, Peter and Ryan, Peter and Ritchie, Scott and Hoffmann, Ary and O’Neill, Scott and Turelli, Michael},
  publisher    = {Public Library of Science},
  title        = {{Supporting Information concerning additional likelihood analyses and results}},
  doi          = {10.1371/journal.pbio.2001894.s014},
  year         = {2017},
}

@misc{9857,
  author       = {Schmidt, Tom and Barton, Nicholas H and Rasic, Gordana and Turley, Andrew and Montgomery, Brian and Iturbe Ormaetxe, Inaki and Cook, Peter and Ryan, Peter and Ritchie, Scott and Hoffmann, Ary and O’Neill, Scott and Turelli, Michael},
  publisher    = {Public Library of Science },
  title        = {{Supporting information concerning observed wMel frequencies and analyses of habitat variables}},
  doi          = {10.1371/journal.pbio.2001894.s015},
  year         = {2017},
}