---
_id: '5396'
abstract:
- lang: eng
text: We consider the problem of inference in agraphical model with binary variables.
While in theory it is arguably preferable to compute marginal probabilities, in
practice researchers often use MAP inference due to the availability of efficient
discrete optimization algorithms. We bridge the gap between the two approaches
by introducing the Discrete Marginals technique in which approximate marginals
are obtained by minimizing an objective function with unary and pair-wise terms
over a discretized domain. This allows the use of techniques originally devel-oped
for MAP-MRF inference and learning. We explore two ways to set up the objective
function - by discretizing the Bethe free energy and by learning it from training
data. Experimental results show that for certain types of graphs a learned function
can out-perform the Bethe approximation. We also establish a link between the
Bethe free energy and submodular functions.
alternative_title:
- IST Austria Technical Report
author:
- first_name: Filip
full_name: Korc, Filip
id: 476A2FD6-F248-11E8-B48F-1D18A9856A87
last_name: Korc
- first_name: Vladimir
full_name: Kolmogorov, Vladimir
id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
last_name: Kolmogorov
- first_name: Christoph
full_name: Lampert, Christoph
id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
last_name: Lampert
orcid: 0000-0001-8622-7887
citation:
ama: Korc F, Kolmogorov V, Lampert C. Approximating Marginals Using Discrete
Energy Minimization. IST Austria; 2012. doi:10.15479/AT:IST-2012-0003
apa: Korc, F., Kolmogorov, V., & Lampert, C. (2012). Approximating marginals
using discrete energy minimization. IST Austria. https://doi.org/10.15479/AT:IST-2012-0003
chicago: Korc, Filip, Vladimir Kolmogorov, and Christoph Lampert. Approximating
Marginals Using Discrete Energy Minimization. IST Austria, 2012. https://doi.org/10.15479/AT:IST-2012-0003.
ieee: F. Korc, V. Kolmogorov, and C. Lampert, Approximating marginals using discrete
energy minimization. IST Austria, 2012.
ista: Korc F, Kolmogorov V, Lampert C. 2012. Approximating marginals using discrete
energy minimization, IST Austria, 13p.
mla: Korc, Filip, et al. Approximating Marginals Using Discrete Energy Minimization.
IST Austria, 2012, doi:10.15479/AT:IST-2012-0003.
short: F. Korc, V. Kolmogorov, C. Lampert, Approximating Marginals Using Discrete
Energy Minimization, IST Austria, 2012.
date_created: 2018-12-12T11:39:06Z
date_published: 2012-07-23T00:00:00Z
date_updated: 2023-02-23T11:13:22Z
day: '23'
ddc:
- '000'
department:
- _id: VlKo
- _id: ChLa
doi: 10.15479/AT:IST-2012-0003
file:
- access_level: open_access
checksum: 7e0ba85ad123b13223aaf6cdde2d288c
content_type: application/pdf
creator: system
date_created: 2018-12-12T11:53:29Z
date_updated: 2020-07-14T12:46:44Z
file_id: '5490'
file_name: IST-2012-0003_IST-2012-0003.pdf
file_size: 618744
relation: main_file
file_date_updated: 2020-07-14T12:46:44Z
has_accepted_license: '1'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: '13'
publication_identifier:
issn:
- 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '36'
related_material:
record:
- id: '3124'
relation: earlier_version
status: public
status: public
title: Approximating marginals using discrete energy minimization
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2012'
...
---
_id: '5398'
abstract:
- lang: eng
text: This document is created as a part of the project “Repository for Research
Data on IST Austria”. It summarises the actual state of research data at IST Austria,
based on survey results. It supports the choice of appropriate software, which
would best fit the requirements of their users, the researchers.
author:
- first_name: Jana
full_name: Porsche, Jana
id: 3252EDC2-F248-11E8-B48F-1D18A9856A87
last_name: Porsche
citation:
ama: Porsche J. Actual State of Research Data @ ISTAustria. IST Austria;
2012.
apa: Porsche, J. (2012). Actual state of research data @ ISTAustria. IST
Austria.
chicago: Porsche, Jana. Actual State of Research Data @ ISTAustria. IST Austria,
2012.
ieee: J. Porsche, Actual state of research data @ ISTAustria. IST Austria,
2012.
ista: Porsche J. 2012. Actual state of research data @ ISTAustria, IST Austria,p.
mla: Porsche, Jana. Actual State of Research Data @ ISTAustria. IST Austria,
2012.
short: J. Porsche, Actual State of Research Data @ ISTAustria, IST Austria, 2012.
date_created: 2018-12-12T11:39:06Z
date_published: 2012-11-12T00:00:00Z
date_updated: 2020-07-14T23:04:49Z
day: '12'
ddc:
- '020'
department:
- _id: E-Lib
file:
- access_level: open_access
checksum: e0a7c041eea1ca4b70ab6f9ec5177f4e
content_type: application/pdf
creator: system
date_created: 2018-12-12T11:53:11Z
date_updated: 2020-07-14T12:46:44Z
file_id: '5472'
file_name: IST-2012-103-v1+1_Actual_state_of_research_data_@_IST_Austria.pdf
file_size: 238544
relation: main_file
file_date_updated: 2020-07-14T12:46:44Z
has_accepted_license: '1'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
publication_status: published
publisher: IST Austria
pubrep_id: '103'
status: public
title: Actual state of research data @ ISTAustria
type: report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2012'
...
---
_id: '5745'
article_processing_charge: No
author:
- first_name: Ashutosh
full_name: Gupta, Ashutosh
last_name: Gupta
citation:
ama: 'Gupta A. Improved Single Pass Algorithms for Resolution Proof Reduction. In:
Automated Technology for Verification and Analysis. Vol 7561. LNCS. Berlin,
Heidelberg: Springer Berlin Heidelberg; 2012:107-121. doi:10.1007/978-3-642-33386-6_10'
apa: 'Gupta, A. (2012). Improved Single Pass Algorithms for Resolution Proof Reduction.
In Automated Technology for Verification and Analysis (Vol. 7561, pp. 107–121).
Berlin, Heidelberg: Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-642-33386-6_10'
chicago: 'Gupta, Ashutosh. “Improved Single Pass Algorithms for Resolution Proof
Reduction.” In Automated Technology for Verification and Analysis, 7561:107–21.
LNCS. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. https://doi.org/10.1007/978-3-642-33386-6_10.'
ieee: 'A. Gupta, “Improved Single Pass Algorithms for Resolution Proof Reduction,”
in Automated Technology for Verification and Analysis, vol. 7561, Berlin,
Heidelberg: Springer Berlin Heidelberg, 2012, pp. 107–121.'
ista: 'Gupta A. 2012.Improved Single Pass Algorithms for Resolution Proof Reduction.
In: Automated Technology for Verification and Analysis. vol. 7561, 107–121.'
mla: Gupta, Ashutosh. “Improved Single Pass Algorithms for Resolution Proof Reduction.”
Automated Technology for Verification and Analysis, vol. 7561, Springer
Berlin Heidelberg, 2012, pp. 107–21, doi:10.1007/978-3-642-33386-6_10.
short: A. Gupta, in:, Automated Technology for Verification and Analysis, Springer
Berlin Heidelberg, Berlin, Heidelberg, 2012, pp. 107–121.
conference:
end_date: 2012-10-06
location: Thiruvananthapuram, Kerala, India
name: ATVA 2012
start_date: 2012-10-03
date_created: 2018-12-18T13:01:46Z
date_published: 2012-01-01T00:00:00Z
date_updated: 2023-09-05T14:15:29Z
ddc:
- '005'
department:
- _id: ToHe
doi: 10.1007/978-3-642-33386-6_10
ec_funded: 1
file:
- access_level: open_access
checksum: 68415837a315de3cc4d120f6019d752c
content_type: application/pdf
creator: dernst
date_created: 2018-12-18T13:07:35Z
date_updated: 2020-07-14T12:47:10Z
file_id: '5746'
file_name: 2012_ATVA_Gupta.pdf
file_size: 465502
relation: main_file
file_date_updated: 2020-07-14T12:47:10Z
has_accepted_license: '1'
intvolume: ' 7561'
language:
- iso: eng
oa: 1
oa_version: None
page: 107-121
place: Berlin, Heidelberg
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
publication: Automated Technology for Verification and Analysis
publication_identifier:
eissn:
- 1611-3349
isbn:
- '9783642333859'
- '9783642333866'
issn:
- 0302-9743
publication_status: published
publisher: Springer Berlin Heidelberg
pubrep_id: '180'
quality_controlled: '1'
series_title: LNCS
status: public
title: Improved Single Pass Algorithms for Resolution Proof Reduction
type: book_chapter
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 7561
year: '2012'
...
---
_id: '5839'
abstract:
- lang: eng
text: "Canny's edge detection algorithm is a classical and robust method for edge
detection in gray-scale images. The two \r\nsignificant features of this method
are introduction of NMS (Non-Maximum Suppression) and double thresholding of \r\nthe
\ gradient image. Due to poor illumination, the region boundaries in
\ an image may become vague, creating \r\nuncertainties in the gradient
\ image. In this paper, we have proposed an algorithm based on the
\ concept of type-2 fuzzy sets to handle uncertainties that automatically
\ selects the threshold values needed to segment the gradient image using
classical Canny’s edge detection algorithm. The results show that our algorithm
works significantly well on different benchmark images as well as medical images
(hand radiography images). "
author:
- first_name: Ranita
full_name: Biswas, Ranita
id: 3C2B033E-F248-11E8-B48F-1D18A9856A87
last_name: Biswas
orcid: 0000-0002-5372-7890
- first_name: Jaya
full_name: Sil, Jaya
last_name: Sil
citation:
ama: Biswas R, Sil J. An Improved Canny Edge Detection Algorithm Based on Type-2
Fuzzy Sets. Procedia Technology. 2012;4:820-824. doi:10.1016/j.protcy.2012.05.134
apa: Biswas, R., & Sil, J. (2012). An Improved Canny Edge Detection Algorithm
Based on Type-2 Fuzzy Sets. Procedia Technology. Elsevier. https://doi.org/10.1016/j.protcy.2012.05.134
chicago: Biswas, Ranita, and Jaya Sil. “An Improved Canny Edge Detection Algorithm
Based on Type-2 Fuzzy Sets.” Procedia Technology. Elsevier, 2012. https://doi.org/10.1016/j.protcy.2012.05.134.
ieee: R. Biswas and J. Sil, “An Improved Canny Edge Detection Algorithm Based on
Type-2 Fuzzy Sets,” Procedia Technology, vol. 4. Elsevier, pp. 820–824,
2012.
ista: Biswas R, Sil J. 2012. An Improved Canny Edge Detection Algorithm Based on
Type-2 Fuzzy Sets. Procedia Technology. 4, 820–824.
mla: Biswas, Ranita, and Jaya Sil. “An Improved Canny Edge Detection Algorithm Based
on Type-2 Fuzzy Sets.” Procedia Technology, vol. 4, Elsevier, 2012, pp.
820–24, doi:10.1016/j.protcy.2012.05.134.
short: R. Biswas, J. Sil, Procedia Technology 4 (2012) 820–824.
date_created: 2019-01-17T11:54:21Z
date_published: 2012-05-01T00:00:00Z
date_updated: 2021-01-12T08:03:43Z
day: '01'
ddc:
- '000'
doi: 10.1016/j.protcy.2012.05.134
extern: '1'
file:
- access_level: open_access
checksum: ba0185986b151d8c11201f48cd505ceb
content_type: application/pdf
creator: dernst
date_created: 2019-01-21T07:28:06Z
date_updated: 2020-07-14T12:47:12Z
file_id: '5863'
file_name: 2012_Procedia_Biswas.pdf
file_size: 305426
relation: main_file
file_date_updated: 2020-07-14T12:47:12Z
has_accepted_license: '1'
intvolume: ' 4'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '05'
oa: 1
oa_version: Published Version
page: 820-824
publication: Procedia Technology
publication_identifier:
issn:
- 2212-0173
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: An Improved Canny Edge Detection Algorithm Based on Type-2 Fuzzy Sets
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 4
year: '2012'
...
---
_id: '596'
abstract:
- lang: eng
text: The human Mediator complex controls RNA polymerase II (pol II) function in
ways that remain incompletely understood. Activator-Mediator binding alters Mediator
structure, and these activator-induced structural shifts appear to play key roles
in regulating transcription. A recent cryo-electron microscopy (EM) analysis revealed
that pol II adopted a stable orientation within a Mediator-pol II-TFIIF assembly
in which Mediator was bound to the activation domain of viral protein 16 (VP16).
Whereas TFIIF was shown to be important for orienting pol II within this assembly,
the potential role of the activator was not assessed. To determine how activator
binding might affect pol II orientation, we isolated human Mediator-pol II-TFIIF
complexes in which Mediator was not bound to an activator. Cryo-EM analysis of
this assembly, coupled with pol II crystal structure docking, revealed that pol
II binds Mediator at the same general location; however, in contrast to VP16-bound
Mediator, pol II does not appear to stably orient in the absence of an activator.
Variability in pol II orientation might be important mechanistically, perhaps
to enable sense and antisense transcription at human promoters. Because Mediator
interacts extensively with pol II, these results suggest that Mediator structural
shifts induced by activator binding help stably orient pol II prior to transcription
initiation.
article_processing_charge: No
author:
- first_name: Carrie A
full_name: Bernecky, Carrie A
id: 2CB9DFE2-F248-11E8-B48F-1D18A9856A87
last_name: Bernecky
orcid: 0000-0003-0893-7036
- first_name: Dylan
full_name: Taatjes, Dylan
last_name: Taatjes
citation:
ama: Bernecky C, Taatjes D. Activator-mediator binding stabilizes RNA polymerase
II orientation within the human mediator-RNA polymerase II-TFIIF assembly. Journal
of Molecular Biology. 2012;417(5):387-394. doi:10.1016/j.jmb.2012.02.014
apa: Bernecky, C., & Taatjes, D. (2012). Activator-mediator binding stabilizes
RNA polymerase II orientation within the human mediator-RNA polymerase II-TFIIF
assembly. Journal of Molecular Biology. Elsevier. https://doi.org/10.1016/j.jmb.2012.02.014
chicago: Bernecky, Carrie, and Dylan Taatjes. “Activator-Mediator Binding Stabilizes
RNA Polymerase II Orientation within the Human Mediator-RNA Polymerase II-TFIIF
Assembly.” Journal of Molecular Biology. Elsevier, 2012. https://doi.org/10.1016/j.jmb.2012.02.014.
ieee: C. Bernecky and D. Taatjes, “Activator-mediator binding stabilizes RNA polymerase
II orientation within the human mediator-RNA polymerase II-TFIIF assembly,” Journal
of Molecular Biology, vol. 417, no. 5. Elsevier, pp. 387–394, 2012.
ista: Bernecky C, Taatjes D. 2012. Activator-mediator binding stabilizes RNA polymerase
II orientation within the human mediator-RNA polymerase II-TFIIF assembly. Journal
of Molecular Biology. 417(5), 387–394.
mla: Bernecky, Carrie, and Dylan Taatjes. “Activator-Mediator Binding Stabilizes
RNA Polymerase II Orientation within the Human Mediator-RNA Polymerase II-TFIIF
Assembly.” Journal of Molecular Biology, vol. 417, no. 5, Elsevier, 2012,
pp. 387–94, doi:10.1016/j.jmb.2012.02.014.
short: C. Bernecky, D. Taatjes, Journal of Molecular Biology 417 (2012) 387–394.
date_created: 2018-12-11T11:47:24Z
date_published: 2012-04-13T00:00:00Z
date_updated: 2021-01-12T08:05:21Z
day: '13'
doi: 10.1016/j.jmb.2012.02.014
extern: '1'
intvolume: ' 417'
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582759/
month: '04'
oa: 1
oa_version: None
page: 387 - 394
publication: Journal of Molecular Biology
publication_status: published
publisher: Elsevier
publist_id: '7208'
status: public
title: Activator-mediator binding stabilizes RNA polymerase II orientation within
the human mediator-RNA polymerase II-TFIIF assembly
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 417
year: '2012'
...
---
_id: '6136'
abstract:
- lang: eng
text: Tonic receptors convey stimulus duration and intensity and are implicated
in homeostatic control. However, how tonic homeostatic signals are generated and
how they reconfigure neural circuits and modify animal behavior is poorly understood.
Here we show that Caenorhabditis elegans O2-sensing neurons are tonic receptors
that continuously signal ambient [O2] to set the animal's behavioral state. Sustained
signaling relied on a Ca2+ relay involving L-type voltage-gated Ca2+ channels,
the ryanodine and the inositol-1,4,5-trisphosphate receptors. Tonic activity evoked
continuous neuropeptide release, which helps elicit the enduring behavioral state
associated with high [O2]. Sustained O2 receptor signaling was propagated to downstream
neural circuits, including the hub interneuron RMG. O2 receptors evoked similar
locomotory states at particular O2 concentrations, regardless of previous d[O2]/dt.
However, a phasic component of the URX receptors' response to high d[O2]/dt, as
well as tonic-to-phasic transformations in downstream interneurons, enabled transient
reorientation movements shaped by d[O2]/dt. Our results highlight how tonic homeostatic
signals can generate both transient and enduring behavioral change.
author:
- first_name: Karl Emanuel
full_name: Busch, Karl Emanuel
last_name: Busch
- first_name: Patrick
full_name: Laurent, Patrick
last_name: Laurent
- first_name: Zoltan
full_name: Soltesz, Zoltan
last_name: Soltesz
- first_name: Robin Joseph
full_name: Murphy, Robin Joseph
last_name: Murphy
- first_name: Olivier
full_name: Faivre, Olivier
last_name: Faivre
- first_name: Berthold
full_name: Hedwig, Berthold
last_name: Hedwig
- first_name: Martin
full_name: Thomas, Martin
last_name: Thomas
- first_name: Heather L
full_name: Smith, Heather L
last_name: Smith
- first_name: Mario
full_name: de Bono, Mario
id: 4E3FF80E-F248-11E8-B48F-1D18A9856A87
last_name: de Bono
orcid: 0000-0001-8347-0443
citation:
ama: Busch KE, Laurent P, Soltesz Z, et al. Tonic signaling from O2 sensors sets
neural circuit activity and behavioral state. Nature Neuroscience. 2012;15(4):581-591.
doi:10.1038/nn.3061
apa: Busch, K. E., Laurent, P., Soltesz, Z., Murphy, R. J., Faivre, O., Hedwig,
B., … de Bono, M. (2012). Tonic signaling from O2 sensors sets neural circuit
activity and behavioral state. Nature Neuroscience. Springer Nature. https://doi.org/10.1038/nn.3061
chicago: Busch, Karl Emanuel, Patrick Laurent, Zoltan Soltesz, Robin Joseph Murphy,
Olivier Faivre, Berthold Hedwig, Martin Thomas, Heather L Smith, and Mario de
Bono. “Tonic Signaling from O2 Sensors Sets Neural Circuit Activity and Behavioral
State.” Nature Neuroscience. Springer Nature, 2012. https://doi.org/10.1038/nn.3061.
ieee: K. E. Busch et al., “Tonic signaling from O2 sensors sets neural circuit
activity and behavioral state,” Nature Neuroscience, vol. 15, no. 4. Springer
Nature, pp. 581–591, 2012.
ista: Busch KE, Laurent P, Soltesz Z, Murphy RJ, Faivre O, Hedwig B, Thomas M, Smith
HL, de Bono M. 2012. Tonic signaling from O2 sensors sets neural circuit activity
and behavioral state. Nature Neuroscience. 15(4), 581–591.
mla: Busch, Karl Emanuel, et al. “Tonic Signaling from O2 Sensors Sets Neural Circuit
Activity and Behavioral State.” Nature Neuroscience, vol. 15, no. 4, Springer
Nature, 2012, pp. 581–91, doi:10.1038/nn.3061.
short: K.E. Busch, P. Laurent, Z. Soltesz, R.J. Murphy, O. Faivre, B. Hedwig, M.
Thomas, H.L. Smith, M. de Bono, Nature Neuroscience 15 (2012) 581–591.
date_created: 2019-03-20T14:23:30Z
date_published: 2012-03-04T00:00:00Z
date_updated: 2021-01-12T08:06:17Z
day: '04'
doi: 10.1038/nn.3061
extern: '1'
external_id:
pmid:
- '22388961'
intvolume: ' 15'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564487/
month: '03'
oa: 1
oa_version: Submitted Version
page: 581-591
pmid: 1
publication: Nature Neuroscience
publication_identifier:
issn:
- 1097-6256
- 1546-1726
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Tonic signaling from O2 sensors sets neural circuit activity and behavioral
state
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 15
year: '2012'
...
---
_id: '6588'
abstract:
- lang: eng
text: First we note that the best polynomial approximation to vertical bar x vertical
bar on the set, which consists of an interval on the positive half-axis and a
point on the negative half-axis, can be given by means of the classical Chebyshev
polynomials. Then we explore the cases when a solution of the related problem
on two intervals can be given in elementary functions.
acknowledgement: "This work is supported by the Austrian Science Fund (FWF), Project
P22025-N18.\r\n"
article_processing_charge: No
article_type: original
author:
- first_name: Florian
full_name: Pausinger, Florian
id: 2A77D7A2-F248-11E8-B48F-1D18A9856A87
last_name: Pausinger
orcid: 0000-0002-8379-3768
citation:
ama: Pausinger F. Elementary solutions of the Bernstein problem on two intervals.
Journal of Mathematical Physics, Analysis, Geometry. 2012;8(1):63-78.
apa: Pausinger, F. (2012). Elementary solutions of the Bernstein problem on two
intervals. Journal of Mathematical Physics, Analysis, Geometry. B. Verkin
Institute for Low Temperature Physics and Engineering.
chicago: Pausinger, Florian. “Elementary Solutions of the Bernstein Problem on Two
Intervals.” Journal of Mathematical Physics, Analysis, Geometry. B. Verkin
Institute for Low Temperature Physics and Engineering, 2012.
ieee: F. Pausinger, “Elementary solutions of the Bernstein problem on two intervals,”
Journal of Mathematical Physics, Analysis, Geometry, vol. 8, no. 1. B.
Verkin Institute for Low Temperature Physics and Engineering, pp. 63–78, 2012.
ista: Pausinger F. 2012. Elementary solutions of the Bernstein problem on two intervals.
Journal of Mathematical Physics, Analysis, Geometry. 8(1), 63–78.
mla: Pausinger, Florian. “Elementary Solutions of the Bernstein Problem on Two Intervals.”
Journal of Mathematical Physics, Analysis, Geometry, vol. 8, no. 1, B.
Verkin Institute for Low Temperature Physics and Engineering, 2012, pp. 63–78.
short: F. Pausinger, Journal of Mathematical Physics, Analysis, Geometry 8 (2012)
63–78.
date_created: 2019-06-27T08:16:56Z
date_published: 2012-01-01T00:00:00Z
date_updated: 2023-10-16T09:41:31Z
day: '01'
department:
- _id: HeEd
external_id:
isi:
- '000301173600004'
intvolume: ' 8'
isi: 1
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://mi.mathnet.ru/eng/jmag525
month: '01'
oa: 1
oa_version: Published Version
page: 63-78
publication: Journal of Mathematical Physics, Analysis, Geometry
publication_identifier:
issn:
- 1812-9471
publication_status: published
publisher: B. Verkin Institute for Low Temperature Physics and Engineering
quality_controlled: '1'
scopus_import: '1'
status: public
title: Elementary solutions of the Bernstein problem on two intervals
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2012'
...
---
_id: '6746'
abstract:
- lang: eng
text: This paper proposes a novel cooperative approach for two-hop amplify-and-forward
(A&F) relaying that exploits both the signal forwarded by the relay and the one
directly transmitted by the source in impulse-radio ultra-wideband (IR-UWB) systems.
Specifically, we focus on a non-coherent setup employing a double-differential
encoding scheme at the source node and a single differential demodulation at the
relay and destination. The log-likelihood ratio based decision rule is derived
at the destination node. A semi-analytical power allocation strategy is presented
by evaluating a closed-form expression for the effective signal to noise ratio
(SNR) at the destination, which is maximized by exhaustive search. Numerical simulations
show that the proposed system outperforms both the direct transmission with single
differential encoding and the non-cooperative multi-hop approach in different
scenarios.
author:
- first_name: Marco
full_name: Mondelli, Marco
id: 27EB676C-8706-11E9-9510-7717E6697425
last_name: Mondelli
orcid: 0000-0002-3242-7020
- first_name: Qi
full_name: Zhou, Qi
last_name: Zhou
- first_name: Xiaoli
full_name: Ma, Xiaoli
last_name: Ma
- first_name: Vincenzo
full_name: Lottici, Vincenzo
last_name: Lottici
citation:
ama: 'Mondelli M, Zhou Q, Ma X, Lottici V. A cooperative approach for amplify-and-forward
differential transmitted reference IR-UWB relay systems. In: 2012 IEEE International
Conference on Acoustics, Speech and Signal Processing (ICASSP). IEEE; 2012:2905-2908.
doi:10.1109/icassp.2012.6288524'
apa: 'Mondelli, M., Zhou, Q., Ma, X., & Lottici, V. (2012). A cooperative approach
for amplify-and-forward differential transmitted reference IR-UWB relay systems.
In 2012 IEEE International Conference on Acoustics, Speech and Signal Processing
(ICASSP) (pp. 2905–2908). Kyoto, Japan: IEEE. https://doi.org/10.1109/icassp.2012.6288524'
chicago: Mondelli, Marco, Qi Zhou, Xiaoli Ma, and Vincenzo Lottici. “A Cooperative
Approach for Amplify-and-Forward Differential Transmitted Reference IR-UWB Relay
Systems.” In 2012 IEEE International Conference on Acoustics, Speech and Signal
Processing (ICASSP), 2905–8. IEEE, 2012. https://doi.org/10.1109/icassp.2012.6288524.
ieee: M. Mondelli, Q. Zhou, X. Ma, and V. Lottici, “A cooperative approach for amplify-and-forward
differential transmitted reference IR-UWB relay systems,” in 2012 IEEE International
Conference on Acoustics, Speech and Signal Processing (ICASSP), Kyoto, Japan,
2012, pp. 2905–2908.
ista: 'Mondelli M, Zhou Q, Ma X, Lottici V. 2012. A cooperative approach for amplify-and-forward
differential transmitted reference IR-UWB relay systems. 2012 IEEE International
Conference on Acoustics, Speech and Signal Processing (ICASSP). ICASSP: International
Conference on Acoustics, Speech and Signal Processing, 2905–2908.'
mla: Mondelli, Marco, et al. “A Cooperative Approach for Amplify-and-Forward Differential
Transmitted Reference IR-UWB Relay Systems.” 2012 IEEE International Conference
on Acoustics, Speech and Signal Processing (ICASSP), IEEE, 2012, pp. 2905–08,
doi:10.1109/icassp.2012.6288524.
short: M. Mondelli, Q. Zhou, X. Ma, V. Lottici, in:, 2012 IEEE International Conference
on Acoustics, Speech and Signal Processing (ICASSP), IEEE, 2012, pp. 2905–2908.
conference:
end_date: 2012-03-30
location: Kyoto, Japan
name: 'ICASSP: International Conference on Acoustics, Speech and Signal Processing'
start_date: 2012-03-25
date_created: 2019-07-31T09:14:48Z
date_published: 2012-07-31T00:00:00Z
date_updated: 2021-01-12T08:08:49Z
day: '31'
doi: 10.1109/icassp.2012.6288524
extern: '1'
language:
- iso: eng
month: '07'
oa_version: None
page: 2905-2908
publication: 2012 IEEE International Conference on Acoustics, Speech and Signal Processing
(ICASSP)
publication_identifier:
issn:
- 1520-6149
publication_status: published
publisher: IEEE
quality_controlled: '1'
status: public
title: A cooperative approach for amplify-and-forward differential transmitted reference
IR-UWB relay systems
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2012'
...
---
_id: '10387'
abstract:
- lang: eng
text: We report numerical simulations of membrane tubulation driven by large colloidal
particles. Using Monte Carlo simulations we study how the process depends on particle
size and binding strength, and present accurate free energy calculations to sort
out how tube formation compares with the competing budding process. We find that
tube formation is a result of the collective behavior of the particles adhering
on the surface, and it occurs for binding strengths that are smaller than those
required for budding. We also find that long linear aggregates of particles forming
on the membrane surface act as nucleation seeds for tubulation by lowering the
free energy barrier associated to the process.
article_number: '188101'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Anđela
full_name: Šarić, Anđela
id: bf63d406-f056-11eb-b41d-f263a6566d8b
last_name: Šarić
orcid: 0000-0002-7854-2139
- first_name: Angelo
full_name: Cacciuto, Angelo
last_name: Cacciuto
citation:
ama: Šarić A, Cacciuto A. Mechanism of membrane tube formation induced by adhesive
nanocomponents. Physical Review Letters. 2012;109(18). doi:10.1103/physrevlett.109.188101
apa: Šarić, A., & Cacciuto, A. (2012). Mechanism of membrane tube formation
induced by adhesive nanocomponents. Physical Review Letters. American Physical
Society. https://doi.org/10.1103/physrevlett.109.188101
chicago: Šarić, Anđela, and Angelo Cacciuto. “Mechanism of Membrane Tube Formation
Induced by Adhesive Nanocomponents.” Physical Review Letters. American
Physical Society, 2012. https://doi.org/10.1103/physrevlett.109.188101.
ieee: A. Šarić and A. Cacciuto, “Mechanism of membrane tube formation induced by
adhesive nanocomponents,” Physical Review Letters, vol. 109, no. 18. American
Physical Society, 2012.
ista: Šarić A, Cacciuto A. 2012. Mechanism of membrane tube formation induced by
adhesive nanocomponents. Physical Review Letters. 109(18), 188101.
mla: Šarić, Anđela, and Angelo Cacciuto. “Mechanism of Membrane Tube Formation Induced
by Adhesive Nanocomponents.” Physical Review Letters, vol. 109, no. 18,
188101, American Physical Society, 2012, doi:10.1103/physrevlett.109.188101.
short: A. Šarić, A. Cacciuto, Physical Review Letters 109 (2012).
date_created: 2021-11-29T14:08:00Z
date_published: 2012-10-31T00:00:00Z
date_updated: 2021-11-29T14:29:25Z
day: '31'
doi: 10.1103/physrevlett.109.188101
extern: '1'
external_id:
arxiv:
- '1206.3528'
pmid:
- '23215334'
intvolume: ' 109'
issue: '18'
keyword:
- general physics and astronomy
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1206.3528
month: '10'
oa: 1
oa_version: Preprint
pmid: 1
publication: Physical Review Letters
publication_identifier:
eissn:
- 1079-7114
issn:
- 0031-9007
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Mechanism of membrane tube formation induced by adhesive nanocomponents
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 109
year: '2012'
...
---
_id: '10388'
abstract:
- lang: eng
text: Using computer simulations, we show that lipid membranes can mediate linear
aggregation of spherical nanoparticles binding to it for a wide range of biologically
relevant bending rigidities. This result is in net contrast with the isotropic
aggregation of nanoparticles on fluid interfaces or the expected clustering of
isotropic insertions in biological membranes. We present a phase diagram indicating
where linear aggregation is expected and compute explicitly the free-energy barriers
associated with linear and isotropic aggregation. Finally, we provide simple scaling
arguments to explain this phenomenology.
acknowledgement: "This work was supported by the National Science Foundation under
Career Grant No. DMR-0846426.\r\n"
article_number: '118101'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Anđela
full_name: Šarić, Anđela
id: bf63d406-f056-11eb-b41d-f263a6566d8b
last_name: Šarić
orcid: 0000-0002-7854-2139
- first_name: Angelo
full_name: Cacciuto, Angelo
last_name: Cacciuto
citation:
ama: Šarić A, Cacciuto A. Fluid membranes can drive linear aggregation of adsorbed
spherical nanoparticles. Physical Review Letters. 2012;108(11). doi:10.1103/physrevlett.108.118101
apa: Šarić, A., & Cacciuto, A. (2012). Fluid membranes can drive linear aggregation
of adsorbed spherical nanoparticles. Physical Review Letters. American
Physical Society. https://doi.org/10.1103/physrevlett.108.118101
chicago: Šarić, Anđela, and Angelo Cacciuto. “Fluid Membranes Can Drive Linear Aggregation
of Adsorbed Spherical Nanoparticles.” Physical Review Letters. American
Physical Society, 2012. https://doi.org/10.1103/physrevlett.108.118101.
ieee: A. Šarić and A. Cacciuto, “Fluid membranes can drive linear aggregation of
adsorbed spherical nanoparticles,” Physical Review Letters, vol. 108, no.
11. American Physical Society, 2012.
ista: Šarić A, Cacciuto A. 2012. Fluid membranes can drive linear aggregation of
adsorbed spherical nanoparticles. Physical Review Letters. 108(11), 118101.
mla: Šarić, Anđela, and Angelo Cacciuto. “Fluid Membranes Can Drive Linear Aggregation
of Adsorbed Spherical Nanoparticles.” Physical Review Letters, vol. 108,
no. 11, 118101, American Physical Society, 2012, doi:10.1103/physrevlett.108.118101.
short: A. Šarić, A. Cacciuto, Physical Review Letters 108 (2012).
date_created: 2021-11-29T14:30:05Z
date_published: 2012-03-14T00:00:00Z
date_updated: 2021-11-29T15:12:13Z
day: '14'
doi: 10.1103/physrevlett.108.118101
extern: '1'
external_id:
arxiv:
- '1201.0036'
pmid:
- '22540513'
intvolume: ' 108'
issue: '11'
keyword:
- general physics and astronomy
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1201.0036
month: '03'
oa: 1
oa_version: Preprint
pmid: 1
publication: Physical Review Letters
publication_identifier:
eissn:
- 1079-7114
issn:
- 0031-9007
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Fluid membranes can drive linear aggregation of adsorbed spherical nanoparticles
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 108
year: '2012'
...
---
_id: '1055'
abstract:
- lang: eng
text: In July, 2011, a 32-year-old man presented with thoracic pain radiating to
the left arm and upper dorsum, shortness of breath, and palpitations. He had had
upper back tension for 6 months. Medical history was unremarkable apart from moderate
nicotine use (two pack-years). Echocardiography, electrocardiography, and laboratory
tests were unremarkable, excluding a cardiac event. CT of the chest after chest
radiography showed a large bulla of 16 cm diameter in the right hemithorax (figure
A). We did not detect radiological evidence of underlying pulmonary disease. The
bulla wall was unremarkable and no structures were seen within the bulla.
acknowledgement: We thank the interdisciplinary team at the ELK Berlin Chest Hospital.
article_processing_charge: No
author:
- first_name: Barbara
full_name: Erne, Barbara
last_name: Erne
- first_name: Mareike
full_name: Graff, Mareike
last_name: Graff
- first_name: Wolfram
full_name: Klemm, Wolfram
last_name: Klemm
- first_name: Johann G
full_name: Danzl, Johann G
id: 42EFD3B6-F248-11E8-B48F-1D18A9856A87
last_name: Danzl
orcid: 0000-0001-8559-3973
- first_name: Gunda
full_name: Leschber, Gunda
last_name: Leschber
citation:
ama: Erne B, Graff M, Klemm W, Danzl JG, Leschber G. Bulla in the lung. The Lancet.
2012;380(9849). doi:10.1016/S0140-6736(12)60690-4
apa: Erne, B., Graff, M., Klemm, W., Danzl, J. G., & Leschber, G. (2012). Bulla
in the lung. The Lancet. Elsevier. https://doi.org/10.1016/S0140-6736(12)60690-4
chicago: Erne, Barbara, Mareike Graff, Wolfram Klemm, Johann G Danzl, and Gunda
Leschber. “Bulla in the Lung.” The Lancet. Elsevier, 2012. https://doi.org/10.1016/S0140-6736(12)60690-4.
ieee: B. Erne, M. Graff, W. Klemm, J. G. Danzl, and G. Leschber, “Bulla in the lung,”
The Lancet, vol. 380, no. 9849. Elsevier, 2012.
ista: Erne B, Graff M, Klemm W, Danzl JG, Leschber G. 2012. Bulla in the lung. The
Lancet. 380(9849).
mla: Erne, Barbara, et al. “Bulla in the Lung.” The Lancet, vol. 380, no.
9849, Elsevier, 2012, doi:10.1016/S0140-6736(12)60690-4.
short: B. Erne, M. Graff, W. Klemm, J.G. Danzl, G. Leschber, The Lancet 380 (2012).
date_created: 2018-12-11T11:49:54Z
date_published: 2012-10-01T00:00:00Z
date_updated: 2021-01-12T06:47:57Z
day: '01'
doi: 10.1016/S0140-6736(12)60690-4
extern: '1'
intvolume: ' 380'
issue: '9849'
language:
- iso: eng
month: '10'
oa_version: None
publication: The Lancet
publication_status: published
publisher: Elsevier
publist_id: '6333'
status: public
title: Bulla in the lung
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 380
year: '2012'
...
---
_id: '1056'
abstract:
- lang: eng
text: We prepare and study a metastable attractive Mott-insulator state formed with
bosonic atoms in a three-dimensional optical lattice. Starting from a Mott insulator
with Cs atoms at weak repulsive interactions, we use a magnetic Feshbach resonance
to tune the interactions to large attractive values and produce a metastable state
pinned by attractive interactions with a lifetime on the order of 10 s. We probe
the (de)excitation spectrum via lattice modulation spectroscopy, measuring the
interaction dependence of two- and three-body bound-state energies. As a result
of increased on-site three-body loss we observe resonance broadening and suppression
of tunneling processes that produce three-body occupation.
acknowledgement: We are indebted to R. Grimm for generous support. We thank J. von
Stecher, P. Johnson, and E. Tiesinga for fruitful discussions. We gratefully acknowledge
funding by the Austrian Science Fund (FWF) within Project No. I153-N16 and within
the framework of the European Science Foundation (ESF) EuroQUASAR collective research
project QuDeGPM, and by the European Research Council (ERC) under Project No. 278417.
article_processing_charge: No
arxiv: 1
author:
- first_name: Manfred
full_name: Mark, Manfred
last_name: Mark
- first_name: Elmar
full_name: Haller, Elmar
last_name: Haller
- first_name: Katharina
full_name: Lauber, Katharina
last_name: Lauber
- first_name: Johann G
full_name: Danzl, Johann G
id: 42EFD3B6-F248-11E8-B48F-1D18A9856A87
last_name: Danzl
orcid: 0000-0001-8559-3973
- first_name: Alexander
full_name: Janisch, Alexander
last_name: Janisch
- first_name: Hans
full_name: Büchler, Hans
last_name: Büchler
- first_name: Andrew
full_name: Daley, Andrew
last_name: Daley
- first_name: Hanns
full_name: Nägerl, Hanns
last_name: Nägerl
citation:
ama: Mark M, Haller E, Lauber K, et al. Preparation and spectroscopy of a metastable
mott-insulator state with attractive interactions. Physical Review Letters.
2012;108(21). doi:10.1103/PhysRevLett.108.215302
apa: Mark, M., Haller, E., Lauber, K., Danzl, J. G., Janisch, A., Büchler, H., …
Nägerl, H. (2012). Preparation and spectroscopy of a metastable mott-insulator
state with attractive interactions. Physical Review Letters. American Physical
Society. https://doi.org/10.1103/PhysRevLett.108.215302
chicago: Mark, Manfred, Elmar Haller, Katharina Lauber, Johann G Danzl, Alexander
Janisch, Hans Büchler, Andrew Daley, and Hanns Nägerl. “Preparation and Spectroscopy
of a Metastable Mott-Insulator State with Attractive Interactions.” Physical
Review Letters. American Physical Society, 2012. https://doi.org/10.1103/PhysRevLett.108.215302.
ieee: M. Mark et al., “Preparation and spectroscopy of a metastable mott-insulator
state with attractive interactions,” Physical Review Letters, vol. 108,
no. 21. American Physical Society, 2012.
ista: Mark M, Haller E, Lauber K, Danzl JG, Janisch A, Büchler H, Daley A, Nägerl
H. 2012. Preparation and spectroscopy of a metastable mott-insulator state with
attractive interactions. Physical Review Letters. 108(21).
mla: Mark, Manfred, et al. “Preparation and Spectroscopy of a Metastable Mott-Insulator
State with Attractive Interactions.” Physical Review Letters, vol. 108,
no. 21, American Physical Society, 2012, doi:10.1103/PhysRevLett.108.215302.
short: M. Mark, E. Haller, K. Lauber, J.G. Danzl, A. Janisch, H. Büchler, A. Daley,
H. Nägerl, Physical Review Letters 108 (2012).
date_created: 2018-12-11T11:49:55Z
date_published: 2012-05-25T00:00:00Z
date_updated: 2021-01-12T06:47:58Z
day: '25'
doi: 10.1103/PhysRevLett.108.215302
extern: '1'
external_id:
arxiv:
- '1201.1008'
intvolume: ' 108'
issue: '21'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1201.1008
month: '05'
oa: 1
oa_version: Preprint
publication: Physical Review Letters
publication_status: published
publisher: American Physical Society
publist_id: '6334'
status: public
title: Preparation and spectroscopy of a metastable mott-insulator state with attractive
interactions
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 108
year: '2012'
...
---
_id: '10750'
abstract:
- lang: eng
text: The goal of this work is to study the superconducting coherence length in
the fluctuation regime in cuprate superconductors. In this work we present cantilever
torque magnetometry measurements of micron-size BSCCO flakes patterned with arrays
of nanometer scale rings or holes. Using ultrasensitive dynamic torque magnetometry,
oscillations in magnetization are observed near Tc as a function of the applied
magnetic flux threading the array. Special effort was made to detect the oscillations
in magnetization at temperatures above Tc, where the Nernst effect and magnetization
measurements suggest the possibility of pairing. To constrain the magnitude of
the coherence length in the fluctuation regime, we will present the dependence
of the amplitude of the h/2e period oscillations as a function of temperature
and hole size.
acknowledgement: This work was supported by the Center for Emergent Superconductivity,
an Energy Frontier Research Center funded by the U.S. DOE, Office of Science, under
Award No. DE-AC0298CH1088.
alternative_title:
- Bulletin of the American Physical Society
article_number: X21.00008
article_processing_charge: No
author:
- first_name: Hryhoriy
full_name: Polshyn, Hryhoriy
id: edfc7cb1-526e-11ec-b05a-e6ecc27e4e48
last_name: Polshyn
orcid: 0000-0001-8223-8896
- first_name: Raffi
full_name: Budakian, Raffi
last_name: Budakian
citation:
ama: 'Polshyn H, Budakian R. Cantilever torque magnetometry study of multiply connected
BSCCO arrays near Tc. In: APS March Meeting 2012. Vol 57. American Physical
Society; 2012.'
apa: 'Polshyn, H., & Budakian, R. (2012). Cantilever torque magnetometry study
of multiply connected BSCCO arrays near Tc. In APS March Meeting 2012 (Vol.
57). Boston, MA, United States: American Physical Society.'
chicago: Polshyn, Hryhoriy, and Raffi Budakian. “Cantilever Torque Magnetometry
Study of Multiply Connected BSCCO Arrays near Tc.” In APS March Meeting 2012,
Vol. 57. American Physical Society, 2012.
ieee: H. Polshyn and R. Budakian, “Cantilever torque magnetometry study of multiply
connected BSCCO arrays near Tc,” in APS March Meeting 2012, Boston, MA,
United States, 2012, vol. 57, no. 1.
ista: 'Polshyn H, Budakian R. 2012. Cantilever torque magnetometry study of multiply
connected BSCCO arrays near Tc. APS March Meeting 2012. APS: American Physical
Society, Bulletin of the American Physical Society, vol. 57, X21.00008.'
mla: Polshyn, Hryhoriy, and Raffi Budakian. “Cantilever Torque Magnetometry Study
of Multiply Connected BSCCO Arrays near Tc.” APS March Meeting 2012, vol.
57, no. 1, X21.00008, American Physical Society, 2012.
short: H. Polshyn, R. Budakian, in:, APS March Meeting 2012, American Physical Society,
2012.
conference:
end_date: 2012-03-02
location: Boston, MA, United States
name: 'APS: American Physical Society'
start_date: 2012-02-27
date_created: 2022-02-08T10:39:08Z
date_published: 2012-02-01T00:00:00Z
date_updated: 2022-02-08T10:48:01Z
day: '01'
extern: '1'
intvolume: ' 57'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://meetings.aps.org/Meeting/MAR12/Event/167014
month: '02'
oa: 1
oa_version: Published Version
publication: APS March Meeting 2012
publication_identifier:
issn:
- 0003-0503
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
status: public
title: Cantilever torque magnetometry study of multiply connected BSCCO arrays near
Tc
type: conference
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 57
year: '2012'
...
---
_id: '9451'
abstract:
- lang: eng
text: The Arabidopsis thaliana central cell, the companion cell of the egg, undergoes
DNA demethylation before fertilization, but the targeting preferences, mechanism,
and biological significance of this process remain unclear. Here, we show that
active DNA demethylation mediated by the DEMETER DNA glycosylase accounts for
all of the demethylation in the central cell and preferentially targets small,
AT-rich, and nucleosome-depleted euchromatic transposable elements. The vegetative
cell, the companion cell of sperm, also undergoes DEMETER-dependent demethylation
of similar sequences, and lack of DEMETER in vegetative cells causes reduced small
RNA–directed DNA methylation of transposons in sperm. Our results demonstrate
that demethylation in companion cells reinforces transposon methylation in plant
gametes and likely contributes to stable silencing of transposable elements across
generations.
article_processing_charge: No
article_type: original
author:
- first_name: Christian A.
full_name: Ibarra, Christian A.
last_name: Ibarra
- first_name: Xiaoqi
full_name: Feng, Xiaoqi
last_name: Feng
- first_name: Vera K.
full_name: Schoft, Vera K.
last_name: Schoft
- first_name: Tzung-Fu
full_name: Hsieh, Tzung-Fu
last_name: Hsieh
- first_name: Rie
full_name: Uzawa, Rie
last_name: Uzawa
- first_name: Jessica A.
full_name: Rodrigues, Jessica A.
last_name: Rodrigues
- first_name: Assaf
full_name: Zemach, Assaf
last_name: Zemach
- first_name: Nina
full_name: Chumak, Nina
last_name: Chumak
- first_name: Adriana
full_name: Machlicova, Adriana
last_name: Machlicova
- first_name: Toshiro
full_name: Nishimura, Toshiro
last_name: Nishimura
- first_name: Denisse
full_name: Rojas, Denisse
last_name: Rojas
- first_name: Robert L.
full_name: Fischer, Robert L.
last_name: Fischer
- first_name: Hisashi
full_name: Tamaru, Hisashi
last_name: Tamaru
- first_name: Daniel
full_name: Zilberman, Daniel
id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
last_name: Zilberman
orcid: 0000-0002-0123-8649
citation:
ama: Ibarra CA, Feng X, Schoft VK, et al. Active DNA demethylation in plant companion
cells reinforces transposon methylation in gametes. Science. 2012;337(6100):1360-1364.
doi:10.1126/science.1224839
apa: Ibarra, C. A., Feng, X., Schoft, V. K., Hsieh, T.-F., Uzawa, R., Rodrigues,
J. A., … Zilberman, D. (2012). Active DNA demethylation in plant companion cells
reinforces transposon methylation in gametes. Science. American Association
for the Advancement of Science. https://doi.org/10.1126/science.1224839
chicago: Ibarra, Christian A., Xiaoqi Feng, Vera K. Schoft, Tzung-Fu Hsieh, Rie
Uzawa, Jessica A. Rodrigues, Assaf Zemach, et al. “Active DNA Demethylation in
Plant Companion Cells Reinforces Transposon Methylation in Gametes.” Science.
American Association for the Advancement of Science, 2012. https://doi.org/10.1126/science.1224839.
ieee: C. A. Ibarra et al., “Active DNA demethylation in plant companion cells
reinforces transposon methylation in gametes,” Science, vol. 337, no. 6100.
American Association for the Advancement of Science, pp. 1360–1364, 2012.
ista: Ibarra CA, Feng X, Schoft VK, Hsieh T-F, Uzawa R, Rodrigues JA, Zemach A,
Chumak N, Machlicova A, Nishimura T, Rojas D, Fischer RL, Tamaru H, Zilberman
D. 2012. Active DNA demethylation in plant companion cells reinforces transposon
methylation in gametes. Science. 337(6100), 1360–1364.
mla: Ibarra, Christian A., et al. “Active DNA Demethylation in Plant Companion Cells
Reinforces Transposon Methylation in Gametes.” Science, vol. 337, no. 6100,
American Association for the Advancement of Science, 2012, pp. 1360–64, doi:10.1126/science.1224839.
short: C.A. Ibarra, X. Feng, V.K. Schoft, T.-F. Hsieh, R. Uzawa, J.A. Rodrigues,
A. Zemach, N. Chumak, A. Machlicova, T. Nishimura, D. Rojas, R.L. Fischer, H.
Tamaru, D. Zilberman, Science 337 (2012) 1360–1364.
date_created: 2021-06-04T07:51:31Z
date_published: 2012-09-14T00:00:00Z
date_updated: 2021-12-14T08:28:51Z
day: '14'
ddc:
- '580'
department:
- _id: DaZi
doi: 10.1126/science.1224839
extern: '1'
external_id:
pmid:
- '22984074'
has_accepted_license: '1'
intvolume: ' 337'
issue: '6100'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034762/
month: '09'
oa: 1
oa_version: Published Version
page: 1360-1364
pmid: 1
publication: Science
publication_identifier:
eissn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Active DNA demethylation in plant companion cells reinforces transposon methylation
in gametes
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 337
year: '2012'
...
---
_id: '9497'
abstract:
- lang: eng
text: The regulation of eukaryotic chromatin relies on interactions between many
epigenetic factors, including histone modifications, DNA methylation, and the
incorporation of histone variants. H2A.Z, one of the most conserved but enigmatic
histone variants that is enriched at the transcriptional start sites of genes,
has been implicated in a variety of chromosomal processes. Recently, we reported
a genome-wide anticorrelation between H2A.Z and DNA methylation, an epigenetic
hallmark of heterochromatin that has also been found in the bodies of active genes
in plants and animals. Here, we investigate the basis of this anticorrelation
using a novel h2a.z loss-of-function line in Arabidopsis thaliana. Through genome-wide
bisulfite sequencing, we demonstrate that loss of H2A.Z in Arabidopsis has only
a minor effect on the level or profile of DNA methylation in genes, and we propose
that the global anticorrelation between DNA methylation and H2A.Z is primarily
caused by the exclusion of H2A.Z from methylated DNA. RNA sequencing and genomic
mapping of H2A.Z show that H2A.Z enrichment across gene bodies, rather than at
the TSS, is correlated with lower transcription levels and higher measures of
gene responsiveness. Loss of H2A.Z causes misregulation of many genes that are
disproportionately associated with response to environmental and developmental
stimuli. We propose that H2A.Z deposition in gene bodies promotes variability
in levels and patterns of gene expression, and that a major function of genic
DNA methylation is to exclude H2A.Z from constitutively expressed genes.
article_number: e1002988
article_processing_charge: No
article_type: original
author:
- first_name: Devin
full_name: Coleman-Derr, Devin
last_name: Coleman-Derr
- first_name: Daniel
full_name: Zilberman, Daniel
id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
last_name: Zilberman
orcid: 0000-0002-0123-8649
citation:
ama: Coleman-Derr D, Zilberman D. Deposition of histone variant H2A.Z within gene
bodies regulates responsive genes. PLoS Genetics. 2012;8(10). doi:10.1371/journal.pgen.1002988
apa: Coleman-Derr, D., & Zilberman, D. (2012). Deposition of histone variant
H2A.Z within gene bodies regulates responsive genes. PLoS Genetics. Public
Library of Science. https://doi.org/10.1371/journal.pgen.1002988
chicago: Coleman-Derr, Devin, and Daniel Zilberman. “Deposition of Histone Variant
H2A.Z within Gene Bodies Regulates Responsive Genes.” PLoS Genetics. Public
Library of Science, 2012. https://doi.org/10.1371/journal.pgen.1002988.
ieee: D. Coleman-Derr and D. Zilberman, “Deposition of histone variant H2A.Z within
gene bodies regulates responsive genes,” PLoS Genetics, vol. 8, no. 10.
Public Library of Science, 2012.
ista: Coleman-Derr D, Zilberman D. 2012. Deposition of histone variant H2A.Z within
gene bodies regulates responsive genes. PLoS Genetics. 8(10), e1002988.
mla: Coleman-Derr, Devin, and Daniel Zilberman. “Deposition of Histone Variant H2A.Z
within Gene Bodies Regulates Responsive Genes.” PLoS Genetics, vol. 8,
no. 10, e1002988, Public Library of Science, 2012, doi:10.1371/journal.pgen.1002988.
short: D. Coleman-Derr, D. Zilberman, PLoS Genetics 8 (2012).
date_created: 2021-06-07T10:55:27Z
date_published: 2012-10-11T00:00:00Z
date_updated: 2021-12-14T08:29:57Z
day: '11'
department:
- _id: DaZi
doi: 10.1371/journal.pgen.1002988
extern: '1'
external_id:
pmid:
- '23071449'
intvolume: ' 8'
issue: '10'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1371/journal.pgen.1002988
month: '10'
oa: 1
oa_version: Published Version
pmid: 1
publication: PLoS Genetics
publication_identifier:
eissn:
- 1553-7404
issn:
- 1553-7390
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Deposition of histone variant H2A.Z within gene bodies regulates responsive
genes
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 8
year: '2012'
...
---
_id: '9499'
abstract:
- lang: eng
text: EMBRYONIC FLOWER1 (EMF1) is a plant-specific gene crucial to Arabidopsis vegetative
development. Loss of function mutants in the EMF1 gene mimic the phenotype caused
by mutations in Polycomb Group protein (PcG) genes, which encode epigenetic repressors
that regulate many aspects of eukaryotic development. In Arabidopsis, Polycomb
Repressor Complex 2 (PRC2), made of PcG proteins, catalyzes trimethylation of
lysine 27 on histone H3 (H3K27me3) and PRC1-like proteins catalyze H2AK119 ubiquitination.
Despite functional similarity to PcG proteins, EMF1 lacks sequence homology with
known PcG proteins; thus, its role in the PcG mechanism is unclear. To study the
EMF1 functions and its mechanism of action, we performed genome-wide mapping of
EMF1 binding and H3K27me3 modification sites in Arabidopsis seedlings. The EMF1
binding pattern is similar to that of H3K27me3 modification on the chromosomal
and genic level. ChIPOTLe peak finding and clustering analyses both show that
the highly trimethylated genes also have high enrichment levels of EMF1 binding,
termed EMF1_K27 genes. EMF1 interacts with regulatory genes, which are silenced
to allow vegetative growth, and with genes specifying cell fates during growth
and differentiation. H3K27me3 marks not only these genes but also some genes that
are involved in endosperm development and maternal effects. Transcriptome analysis,
coupled with the H3K27me3 pattern, of EMF1_K27 genes in emf1 and PRC2 mutants
showed that EMF1 represses gene activities via diverse mechanisms and plays a
novel role in the PcG mechanism.
article_number: e1002512
article_processing_charge: No
article_type: original
author:
- first_name: Sang Yeol
full_name: Kim, Sang Yeol
last_name: Kim
- first_name: Jungeun
full_name: Lee, Jungeun
last_name: Lee
- first_name: Leor
full_name: Eshed-Williams, Leor
last_name: Eshed-Williams
- first_name: Daniel
full_name: Zilberman, Daniel
id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
last_name: Zilberman
orcid: 0000-0002-0123-8649
- first_name: Z. Renee
full_name: Sung, Z. Renee
last_name: Sung
citation:
ama: Kim SY, Lee J, Eshed-Williams L, Zilberman D, Sung ZR. EMF1 and PRC2 cooperate
to repress key regulators of Arabidopsis development. PLoS Genetics. 2012;8(3).
doi:10.1371/journal.pgen.1002512
apa: Kim, S. Y., Lee, J., Eshed-Williams, L., Zilberman, D., & Sung, Z. R. (2012).
EMF1 and PRC2 cooperate to repress key regulators of Arabidopsis development.
PLoS Genetics. Public Library of Science. https://doi.org/10.1371/journal.pgen.1002512
chicago: Kim, Sang Yeol, Jungeun Lee, Leor Eshed-Williams, Daniel Zilberman, and
Z. Renee Sung. “EMF1 and PRC2 Cooperate to Repress Key Regulators of Arabidopsis
Development.” PLoS Genetics. Public Library of Science, 2012. https://doi.org/10.1371/journal.pgen.1002512.
ieee: S. Y. Kim, J. Lee, L. Eshed-Williams, D. Zilberman, and Z. R. Sung, “EMF1
and PRC2 cooperate to repress key regulators of Arabidopsis development,” PLoS
Genetics, vol. 8, no. 3. Public Library of Science, 2012.
ista: Kim SY, Lee J, Eshed-Williams L, Zilberman D, Sung ZR. 2012. EMF1 and PRC2
cooperate to repress key regulators of Arabidopsis development. PLoS Genetics.
8(3), e1002512.
mla: Kim, Sang Yeol, et al. “EMF1 and PRC2 Cooperate to Repress Key Regulators of
Arabidopsis Development.” PLoS Genetics, vol. 8, no. 3, e1002512, Public
Library of Science, 2012, doi:10.1371/journal.pgen.1002512.
short: S.Y. Kim, J. Lee, L. Eshed-Williams, D. Zilberman, Z.R. Sung, PLoS Genetics
8 (2012).
date_created: 2021-06-07T11:07:56Z
date_published: 2012-03-22T00:00:00Z
date_updated: 2021-12-14T08:31:14Z
day: '22'
department:
- _id: DaZi
doi: 10.1371/journal.pgen.1002512
extern: '1'
external_id:
pmid:
- '22457632'
intvolume: ' 8'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1371/journal.pgen.1002512
month: '03'
oa: 1
oa_version: Published Version
pmid: 1
publication: PLoS Genetics
publication_identifier:
eissn:
- 1553-7404
issn:
- 1553-7390
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: EMF1 and PRC2 cooperate to repress key regulators of Arabidopsis development
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 8
year: '2012'
...
---
_id: '9528'
abstract:
- lang: eng
text: Accumulating evidence points toward diverse functions for plant chromatin.
Remarkable progress has been made over the last few years in elucidating the mechanisms
for a number of these functions. Activity of the histone demethylase IBM1 accurately
targets DNA methylation to silent repeats and transposable elements, not to genes.
A genetic screen uncovered the surprising role of H2A.Z-containing nucleosomes
in sensing precise differences in ambient temperature and consequent gene regulation.
Precise maintenance of chromosome number is assured by a histone modification
that suppresses inappropriate DNA replication and by centromeric histone H3 regulation
of chromosome segregation. Histones and noncoding RNAs regulate FLOWERING LOCUS
C, the expression of which quantitatively measures the duration of cold exposure,
functioning as memory of winter. These findings are a testament to the power of
using plants to research chromatin organization, and demonstrate examples of how
chromatin functions to achieve biological accuracy, precision, and memory.
article_processing_charge: No
article_type: review
author:
- first_name: Jason T.
full_name: Huff, Jason T.
last_name: Huff
- first_name: Daniel
full_name: Zilberman, Daniel
id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
last_name: Zilberman
orcid: 0000-0002-0123-8649
citation:
ama: Huff JT, Zilberman D. Regulation of biological accuracy, precision, and memory
by plant chromatin organization. Current Opinion in Genetics and Development.
2012;22(2):132-138. doi:10.1016/j.gde.2012.01.007
apa: Huff, J. T., & Zilberman, D. (2012). Regulation of biological accuracy,
precision, and memory by plant chromatin organization. Current Opinion in Genetics
and Development. Elsevier. https://doi.org/10.1016/j.gde.2012.01.007
chicago: Huff, Jason T., and Daniel Zilberman. “Regulation of Biological Accuracy,
Precision, and Memory by Plant Chromatin Organization.” Current Opinion in
Genetics and Development. Elsevier, 2012. https://doi.org/10.1016/j.gde.2012.01.007.
ieee: J. T. Huff and D. Zilberman, “Regulation of biological accuracy, precision,
and memory by plant chromatin organization,” Current Opinion in Genetics and
Development, vol. 22, no. 2. Elsevier, pp. 132–138, 2012.
ista: Huff JT, Zilberman D. 2012. Regulation of biological accuracy, precision,
and memory by plant chromatin organization. Current Opinion in Genetics and Development.
22(2), 132–138.
mla: Huff, Jason T., and Daniel Zilberman. “Regulation of Biological Accuracy, Precision,
and Memory by Plant Chromatin Organization.” Current Opinion in Genetics and
Development, vol. 22, no. 2, Elsevier, 2012, pp. 132–38, doi:10.1016/j.gde.2012.01.007.
short: J.T. Huff, D. Zilberman, Current Opinion in Genetics and Development 22 (2012)
132–138.
date_created: 2021-06-08T08:58:52Z
date_published: 2012-04-01T00:00:00Z
date_updated: 2021-12-14T08:32:38Z
department:
- _id: DaZi
doi: 10.1016/j.gde.2012.01.007
extern: '1'
external_id:
pmid:
- '22336527'
intvolume: ' 22'
issue: '2'
language:
- iso: eng
month: '04'
oa_version: None
page: 132-138
pmid: 1
publication: Current Opinion in Genetics and Development
publication_identifier:
issn:
- 0959-437X
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Regulation of biological accuracy, precision, and memory by plant chromatin
organization
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 22
year: '2012'
...
---
_id: '9535'
abstract:
- lang: eng
text: The most well-studied function of DNA methylation in eukaryotic cells is the
transcriptional silencing of genes and transposons. More recent results showed
that many eukaryotes methylate the bodies of genes as well and that this methylation
correlates with transcriptional activity rather than repression. The purpose of
gene body methylation remains mysterious, but is potentially related to the histone
variant H2A.Z. Studies in plants and animals have shown that the genome-wide distributions
of H2A.Z and DNA methylation are strikingly anticorrelated. Furthermore, we and
other investigators have shown that this relationship is likely to be the result
of an ancient but unknown mechanism by which DNA methylation prevents the incorporation
of H2A.Z. Recently, we discovered strong correlations between the presence of
H2A.Z within gene bodies, the degree to which a gene's expression varies across
tissue types or environmental conditions, and transcriptional misregulation in
an h2a.z mutant. We propose that one basal function of gene body methylation is
the establishment of constitutive expression patterns within housekeeping genes
by excluding H2A.Z from their bodies.
article_processing_charge: No
article_type: review
author:
- first_name: D.
full_name: Coleman-Derr, D.
last_name: Coleman-Derr
- first_name: Daniel
full_name: Zilberman, Daniel
id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
last_name: Zilberman
orcid: 0000-0002-0123-8649
citation:
ama: Coleman-Derr D, Zilberman D. DNA methylation, H2A.Z, and the regulation of
constitutive expression. Cold Spring Harbor Symposia on Quantitative Biology.
2012;77:147-154. doi:10.1101/sqb.2012.77.014944
apa: Coleman-Derr, D., & Zilberman, D. (2012). DNA methylation, H2A.Z, and the
regulation of constitutive expression. Cold Spring Harbor Symposia on Quantitative
Biology. Cold Spring Harbor Laboratory Press. https://doi.org/10.1101/sqb.2012.77.014944
chicago: Coleman-Derr, D., and Daniel Zilberman. “DNA Methylation, H2A.Z, and the
Regulation of Constitutive Expression.” Cold Spring Harbor Symposia on Quantitative
Biology. Cold Spring Harbor Laboratory Press, 2012. https://doi.org/10.1101/sqb.2012.77.014944.
ieee: D. Coleman-Derr and D. Zilberman, “DNA methylation, H2A.Z, and the regulation
of constitutive expression,” Cold Spring Harbor Symposia on Quantitative Biology,
vol. 77. Cold Spring Harbor Laboratory Press, pp. 147–154, 2012.
ista: Coleman-Derr D, Zilberman D. 2012. DNA methylation, H2A.Z, and the regulation
of constitutive expression. Cold Spring Harbor Symposia on Quantitative Biology.
77, 147–154.
mla: Coleman-Derr, D., and Daniel Zilberman. “DNA Methylation, H2A.Z, and the Regulation
of Constitutive Expression.” Cold Spring Harbor Symposia on Quantitative Biology,
vol. 77, Cold Spring Harbor Laboratory Press, 2012, pp. 147–54, doi:10.1101/sqb.2012.77.014944.
short: D. Coleman-Derr, D. Zilberman, Cold Spring Harbor Symposia on Quantitative
Biology 77 (2012) 147–154.
date_created: 2021-06-08T13:01:23Z
date_published: 2012-12-18T00:00:00Z
date_updated: 2021-12-14T08:33:09Z
day: '18'
department:
- _id: DaZi
doi: 10.1101/sqb.2012.77.014944
extern: '1'
external_id:
pmid:
- '23250988'
intvolume: ' 77'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1101/sqb.2012.77.014944
month: '12'
oa: 1
oa_version: Published Version
page: 147-154
pmid: 1
publication: Cold Spring Harbor Symposia on Quantitative Biology
publication_identifier:
eissn:
- 1943-4456
issn:
- 0091-7451
publication_status: published
publisher: Cold Spring Harbor Laboratory Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: DNA methylation, H2A.Z, and the regulation of constitutive expression
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 77
year: '2012'
...
---
_id: '966'
abstract:
- lang: eng
text: Motivated by recent experiments on Ba3NiSb2O 9, we investigate possible quantum
spin liquid ground states for spin S=1 Heisenberg models on the triangular lattice.
We use variational Monte Carlo techniques to calculate the energies of microscopic
spin liquid wave functions where spin is represented by three flavors of fermionic
spinon operators. These energies are compared with the energies of various competing
three-sublattice ordered states. Our approach shows that the antiferromagnetic
Heisenberg model with biquadratic term and single-ion anisotropy does not have
a low-temperature spin liquid phase. However, for an SU(3)-invariant model with
sufficiently strong ring-exchange terms, we find a paired chiral quantum spin
liquid with a Fermi surface of deconfined spinons that is stable against all types
of ordering patterns we considered. We discuss the physics of this exotic spin
liquid state in relation to the recent experiment and suggest new ways to test
this scenario.
acknowledgement: We thank Kuang-Ting Chen, Rebecca Flint, Dmitri Ivanov, Z.-X. Liu,
Tai-Kai Ng, Lara Thompson, Tamás Tóth, and Fa Wang for helpful discussions. T.S.
is supported by NSF DMR 1005434. P.A.L. is supported by NSF DMR 1104498. S.B. acknowledges
support from the Swiss National Science Foundation (SNSF).
author:
- first_name: Samuel
full_name: Bieri, Samuel
last_name: Bieri
- first_name: Maksym
full_name: Maksym Serbyn
id: 47809E7E-F248-11E8-B48F-1D18A9856A87
last_name: Serbyn
orcid: 0000-0002-2399-5827
- first_name: Todadri
full_name: Senthil, Todadri S
last_name: Senthil
- first_name: Patrick
full_name: Lee, Patrick
last_name: Lee
citation:
ama: Bieri S, Serbyn M, Senthil T, Lee P. Paired chiral spin liquid with a Fermi
surface in S=1 model on the triangular lattice. Physical Review B - Condensed
Matter and Materials Physics. 2012;86(22). doi:10.1103/PhysRevB.86.224409
apa: Bieri, S., Serbyn, M., Senthil, T., & Lee, P. (2012). Paired chiral spin
liquid with a Fermi surface in S=1 model on the triangular lattice. Physical
Review B - Condensed Matter and Materials Physics. American Physical Society.
https://doi.org/10.1103/PhysRevB.86.224409
chicago: Bieri, Samuel, Maksym Serbyn, Todadri Senthil, and Patrick Lee. “Paired
Chiral Spin Liquid with a Fermi Surface in S=1 Model on the Triangular Lattice.”
Physical Review B - Condensed Matter and Materials Physics. American Physical
Society, 2012. https://doi.org/10.1103/PhysRevB.86.224409.
ieee: S. Bieri, M. Serbyn, T. Senthil, and P. Lee, “Paired chiral spin liquid with
a Fermi surface in S=1 model on the triangular lattice,” Physical Review B
- Condensed Matter and Materials Physics, vol. 86, no. 22. American Physical
Society, 2012.
ista: Bieri S, Serbyn M, Senthil T, Lee P. 2012. Paired chiral spin liquid with
a Fermi surface in S=1 model on the triangular lattice. Physical Review B - Condensed
Matter and Materials Physics. 86(22).
mla: Bieri, Samuel, et al. “Paired Chiral Spin Liquid with a Fermi Surface in S=1
Model on the Triangular Lattice.” Physical Review B - Condensed Matter and
Materials Physics, vol. 86, no. 22, American Physical Society, 2012, doi:10.1103/PhysRevB.86.224409.
short: S. Bieri, M. Serbyn, T. Senthil, P. Lee, Physical Review B - Condensed Matter
and Materials Physics 86 (2012).
date_created: 2018-12-11T11:49:27Z
date_published: 2012-12-13T00:00:00Z
date_updated: 2021-01-12T08:22:18Z
day: '13'
doi: 10.1103/PhysRevB.86.224409
extern: 1
intvolume: ' 86'
issue: '22'
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1208.3231
month: '12'
oa: 1
publication: Physical Review B - Condensed Matter and Materials Physics
publication_status: published
publisher: American Physical Society
publist_id: '6431'
quality_controlled: 0
status: public
title: Paired chiral spin liquid with a Fermi surface in S=1 model on the triangular
lattice
type: journal_article
volume: 86
year: '2012'
...
---
_id: '9755'
abstract:
- lang: eng
text: Due to the omnipresent risk of epidemics, insect societies have evolved sophisticated
disease defences at the individual and colony level. An intriguing yet little
understood phenomenon is that social contact to pathogen-exposed individuals reduces
susceptibility of previously naive nestmates to this pathogen. We tested whether
such social immunisation in Lasius ants against the entomopathogenic fungus Metarhizium
anisopliae is based on active upregulation of the immune system of nestmates following
contact to an infectious individual or passive protection via transfer of immune
effectors among group members—that is, active versus passive immunisation. We
found no evidence for involvement of passive immunisation via transfer of antimicrobials
among colony members. Instead, intensive allogrooming behaviour between naive
and pathogen-exposed ants before fungal conidia firmly attached to their cuticle
suggested passage of the pathogen from the exposed individuals to their nestmates.
By tracing fluorescence-labelled conidia we indeed detected frequent pathogen
transfer to the nestmates, where they caused low-level infections as revealed
by growth of small numbers of fungal colony forming units from their dissected
body content. These infections rarely led to death, but instead promoted an enhanced
ability to inhibit fungal growth and an active upregulation of immune genes involved
in antifungal defences (defensin and prophenoloxidase, PPO). Contrarily, there
was no upregulation of the gene cathepsin L, which is associated with antibacterial
and antiviral defences, and we found no increased antibacterial activity of nestmates
of fungus-exposed ants. This indicates that social immunisation after fungal exposure
is specific, similar to recent findings for individual-level immune priming in
invertebrates. Epidemiological modeling further suggests that active social immunisation
is adaptive, as it leads to faster elimination of the disease and lower death
rates than passive immunisation. Interestingly, humans have also utilised the
protective effect of low-level infections to fight smallpox by intentional transfer
of low pathogen doses (“variolation” or “inoculation”).
article_processing_charge: No
author:
- first_name: Matthias
full_name: Konrad, Matthias
id: 46528076-F248-11E8-B48F-1D18A9856A87
last_name: Konrad
- first_name: Meghan
full_name: Vyleta, Meghan
id: 418901AA-F248-11E8-B48F-1D18A9856A87
last_name: Vyleta
- first_name: Fabian
full_name: Theis, Fabian
last_name: Theis
- first_name: Miriam
full_name: Stock, Miriam
id: 42462816-F248-11E8-B48F-1D18A9856A87
last_name: Stock
- first_name: Martina
full_name: Klatt, Martina
id: E60F29C6-E9AE-11E9-AF6E-D190C7302F38
last_name: Klatt
- first_name: Verena
full_name: Drescher, Verena
last_name: Drescher
- first_name: Carsten
full_name: Marr, Carsten
last_name: Marr
- first_name: Line V
full_name: Ugelvig, Line V
id: 3DC97C8E-F248-11E8-B48F-1D18A9856A87
last_name: Ugelvig
orcid: 0000-0003-1832-8883
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
citation:
ama: 'Konrad M, Vyleta M, Theis F, et al. Data from: Social transfer of pathogenic
fungus promotes active immunisation in ant colonies. 2012. doi:10.5061/dryad.sv37s'
apa: 'Konrad, M., Vyleta, M., Theis, F., Stock, M., Klatt, M., Drescher, V., … Cremer,
S. (2012). Data from: Social transfer of pathogenic fungus promotes active immunisation
in ant colonies. Dryad. https://doi.org/10.5061/dryad.sv37s'
chicago: 'Konrad, Matthias, Meghan Vyleta, Fabian Theis, Miriam Stock, Martina Klatt,
Verena Drescher, Carsten Marr, Line V Ugelvig, and Sylvia Cremer. “Data from:
Social Transfer of Pathogenic Fungus Promotes Active Immunisation in Ant Colonies.”
Dryad, 2012. https://doi.org/10.5061/dryad.sv37s.'
ieee: 'M. Konrad et al., “Data from: Social transfer of pathogenic fungus
promotes active immunisation in ant colonies.” Dryad, 2012.'
ista: 'Konrad M, Vyleta M, Theis F, Stock M, Klatt M, Drescher V, Marr C, Ugelvig
LV, Cremer S. 2012. Data from: Social transfer of pathogenic fungus promotes active
immunisation in ant colonies, Dryad, 10.5061/dryad.sv37s.'
mla: 'Konrad, Matthias, et al. Data from: Social Transfer of Pathogenic Fungus
Promotes Active Immunisation in Ant Colonies. Dryad, 2012, doi:10.5061/dryad.sv37s.'
short: M. Konrad, M. Vyleta, F. Theis, M. Stock, M. Klatt, V. Drescher, C. Marr,
L.V. Ugelvig, S. Cremer, (2012).
date_created: 2021-07-30T08:39:13Z
date_published: 2012-09-27T00:00:00Z
date_updated: 2023-02-23T11:18:41Z
day: '27'
department:
- _id: SyCr
doi: 10.5061/dryad.sv37s
main_file_link:
- open_access: '1'
url: https://doi.org/10.5061/dryad.sv37s
month: '09'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
record:
- id: '3242'
relation: used_in_publication
status: public
status: public
title: 'Data from: Social transfer of pathogenic fungus promotes active immunisation
in ant colonies'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2012'
...