[{"doi":"10.1016/j.beproc.2012.09.006","language":[{"iso":"eng"}],"year":"2012","publisher":"Elsevier","date_updated":"2021-01-12T07:40:06Z","status":"public","type":"journal_article","author":[{"id":"4C8C26A4-F248-11E8-B48F-1D18A9856A87","last_name":"Jesse","first_name":"Fabienne","full_name":"Jesse, Fabienne"},{"full_name":"Riebel, Katharina","first_name":"Katharina","last_name":"Riebel"}],"_id":"2963","day":"01","publication_status":"published","oa_version":"None","page":"262 - 266","date_published":"2012-11-01T00:00:00Z","abstract":[{"lang":"eng","text":"Zebra finches are an ubiquitous model system for the study of vocal learning in animal communication. Their song has been well described, but its possible function(s) in social communication are only partly understood. The so-called ‘directed song’ is a high-intensity, high-performance song given during courtship in close proximity to the female, which is known to mediate mate choice and mating. However, this singing mode constitutes only a fraction of zebra finch males’ prolific song output. Potential communicative functions of their second, ‘undirected’ singing mode remain unresolved in the face of contradicting reports of both facilitating and inhibiting effects of social company on singing. We addressed this issue by experimentally manipulating social contexts in a within-subject design, comparing a solo versus male or female only company condition, each lasting for 24 hours. Males’ total song output was significantly higher when a conspecific was in audible and visible distance than when they were alone. Male and female company had an equally facilitating effect on song output. Our findings thus indicate that singing motivation is facilitated rather than inhibited by social company, suggesting that singing in zebra finches might function both in inter- and intrasexual communication. "}],"date_created":"2018-12-11T12:00:35Z","citation":{"mla":"Jesse, Fabienne, and Katharina Riebel. “Social Facilitation of Male Song by Male and Female Conspecifics in the Zebra Finch, Taeniopygia Guttata.” <i>Behavioural Processes</i>, vol. 91, no. 3, Elsevier, 2012, pp. 262–66, doi:<a href=\"https://doi.org/10.1016/j.beproc.2012.09.006\">10.1016/j.beproc.2012.09.006</a>.","apa":"Jesse, F., &#38; Riebel, K. (2012). Social facilitation of male song by male and female conspecifics in the zebra finch, Taeniopygia guttata. <i>Behavioural Processes</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.beproc.2012.09.006\">https://doi.org/10.1016/j.beproc.2012.09.006</a>","short":"F. Jesse, K. Riebel, Behavioural Processes 91 (2012) 262–266.","ista":"Jesse F, Riebel K. 2012. Social facilitation of male song by male and female conspecifics in the zebra finch, Taeniopygia guttata. Behavioural Processes. 91(3), 262–266.","ama":"Jesse F, Riebel K. Social facilitation of male song by male and female conspecifics in the zebra finch, Taeniopygia guttata. <i>Behavioural Processes</i>. 2012;91(3):262-266. doi:<a href=\"https://doi.org/10.1016/j.beproc.2012.09.006\">10.1016/j.beproc.2012.09.006</a>","chicago":"Jesse, Fabienne, and Katharina Riebel. “Social Facilitation of Male Song by Male and Female Conspecifics in the Zebra Finch, Taeniopygia Guttata.” <i>Behavioural Processes</i>. Elsevier, 2012. <a href=\"https://doi.org/10.1016/j.beproc.2012.09.006\">https://doi.org/10.1016/j.beproc.2012.09.006</a>.","ieee":"F. Jesse and K. Riebel, “Social facilitation of male song by male and female conspecifics in the zebra finch, Taeniopygia guttata,” <i>Behavioural Processes</i>, vol. 91, no. 3. Elsevier, pp. 262–266, 2012."},"department":[{"_id":"JoBo"}],"issue":"3","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","intvolume":"        91","month":"11","publist_id":"3756","quality_controlled":"1","publication":"Behavioural Processes","title":"Social facilitation of male song by male and female conspecifics in the zebra finch, Taeniopygia guttata","volume":91},{"publication_identifier":{"issn":["2663-337X"]},"publist_id":"3755","month":"06","title":"Active properties of hippocampal CA3 pyramidal neuron dendrites","related_material":{"record":[{"status":"public","id":"3258","relation":"part_of_dissertation"}]},"supervisor":[{"last_name":"Jonas","id":"353C1B58-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5001-4804","full_name":"Jonas, Peter M","first_name":"Peter M"}],"citation":{"ieee":"S. Kim, “Active properties of hippocampal CA3 pyramidal neuron dendrites,” Institute of Science and Technology Austria, 2012.","chicago":"Kim, Sooyun. “Active Properties of Hippocampal CA3 Pyramidal Neuron Dendrites.” Institute of Science and Technology Austria, 2012.","ama":"Kim S. Active properties of hippocampal CA3 pyramidal neuron dendrites. 2012.","apa":"Kim, S. (2012). <i>Active properties of hippocampal CA3 pyramidal neuron dendrites</i>. Institute of Science and Technology Austria.","ista":"Kim S. 2012. Active properties of hippocampal CA3 pyramidal neuron dendrites. Institute of Science and Technology Austria.","short":"S. Kim, Active Properties of Hippocampal CA3 Pyramidal Neuron Dendrites, Institute of Science and Technology Austria, 2012.","mla":"Kim, Sooyun. <i>Active Properties of Hippocampal CA3 Pyramidal Neuron Dendrites</i>. Institute of Science and Technology Austria, 2012."},"department":[{"_id":"PeJo"},{"_id":"GradSch"}],"date_created":"2018-12-11T12:00:35Z","alternative_title":["ISTA Thesis"],"article_processing_charge":"No","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","_id":"2964","author":[{"id":"394AB1C8-F248-11E8-B48F-1D18A9856A87","last_name":"Kim","first_name":"Sooyun","full_name":"Kim, Sooyun"}],"degree_awarded":"PhD","abstract":[{"lang":"eng","text":"CA3 pyramidal neurons are important for memory formation and pattern completion in the hippocampal network. These neurons receive multiple excitatory inputs from numerous sources. Therefore, the rules of spatiotemporal integration of multiple synaptic inputs and propagation of action potentials are important to understand how CA3 neurons contribute to higher brain functions at cellular level. By using confocally targeted patch-clamp recording techniques, we investigated the biophysical properties of rat CA3 pyramidal neuron dendrites. We found two distinct dendritic domains critical for action potential initiation and propagation: In the proximal domain, action potentials initiated in the axon backpropagate actively with large amplitude and fast time course. In the distal domain, Na+-channel mediated dendritic spikes are efficiently evoked by local dendritic depolarization or waveforms mimicking synaptic events. These findings can be explained by a high Na+-to-K+ conductance density ratio of CA3 pyramidal neuron dendrites. The results challenge the prevailing view that proximal mossy fiber inputs activate CA3 pyramidal neurons more efficiently than distal perforant inputs by showing that the distal synapses trigger a different form of activity represented by dendritic spikes. The high probability of dendritic spike initiation in the distal area may enhance the computational power of CA3 pyramidal neurons in the hippocampal network.  "}],"day":"01","page":"65","date_published":"2012-06-01T00:00:00Z","oa_version":"None","publication_status":"published","year":"2012","publisher":"Institute of Science and Technology Austria","date_updated":"2023-09-07T11:43:51Z","language":[{"iso":"eng"}],"type":"dissertation","status":"public"},{"date_updated":"2021-01-12T07:40:07Z","status":"public","license":"https://creativecommons.org/licenses/by/4.0/","popular_science":"1","oa_version":"Published Version","page":"200 - 212","publication_status":"published","day":"01","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"abstract":[{"lang":"eng","text":"Dieser Artikel soll die sechs verschiedenen Creative Commons Lizenzen erläutern und ihre Bedeutung im Rahmen des wissenschaftlichen Publizierens und des Open Access erklären (CC-BY, CC-BY-SA, CC-BY-NC, CC-BY-ND, CC-BYNC-SA, CC-BY-NC-ND)."}],"pubrep_id":"95","citation":{"apa":"Danowski, P. (2012). Kontext Open Access: Creative Commons. <i>Mitteilungen der Vereinigung Österreichischer Bibliothekarinnen &#38; Bibliothekare</i>. VÖB.","mla":"Danowski, Patrick. “Kontext Open Access: Creative Commons.” <i>Mitteilungen der Vereinigung Österreichischer Bibliothekarinnen &#38; Bibliothekare</i>, vol. 65, no. 2, VÖB, 2012, pp. 200–12.","ista":"Danowski P. 2012. Kontext Open Access: Creative Commons. Mitteilungen der Vereinigung Österreichischer Bibliothekarinnen &#38; Bibliothekare. 65(2), 200–212.","short":"P. Danowski, Mitteilungen der Vereinigung Österreichischer Bibliothekarinnen &#38; Bibliothekare 65 (2012) 200–212.","ama":"Danowski P. Kontext Open Access: Creative Commons. <i>Mitteilungen der Vereinigung Österreichischer Bibliothekarinnen &#38; Bibliothekare</i>. 2012;65(2):200-212.","chicago":"Danowski, Patrick. “Kontext Open Access: Creative Commons.” <i>Mitteilungen der Vereinigung Österreichischer Bibliothekarinnen &#38; Bibliothekare</i>. VÖB, 2012.","ieee":"P. Danowski, “Kontext Open Access: Creative Commons,” <i>Mitteilungen der Vereinigung Österreichischer Bibliothekarinnen &#38; Bibliothekare</i>, vol. 65, no. 2. VÖB, pp. 200–212, 2012."},"issue":"2","scopus_import":1,"has_accepted_license":"1","main_file_link":[{"open_access":"1","url":" http://hdl.handle.net/10760/17625"}],"publication":"Mitteilungen der Vereinigung Österreichischer Bibliothekarinnen & Bibliothekare","title":"Kontext Open Access: Creative Commons","file":[{"access_level":"open_access","content_type":"application/pdf","relation":"main_file","creator":"system","file_id":"4703","checksum":"162eea47d9d840c26b496ba6ae4d1c09","date_created":"2018-12-12T10:08:42Z","date_updated":"2020-07-14T12:45:57Z","file_name":"IST-2012-95-v1+1_sp-beitrag_danowski_kontext_open_access_creative_commons.pdf","file_size":503345}],"language":[{"iso":"ger"}],"publisher":"VÖB","year":"2012","type":"journal_article","author":[{"orcid":"0000-0002-6026-4409","id":"2EBD1598-F248-11E8-B48F-1D18A9856A87","last_name":"Danowski","first_name":"Patrick","full_name":"Danowski, Patrick"}],"oa":1,"_id":"2965","date_published":"2012-09-01T00:00:00Z","date_created":"2018-12-11T12:00:35Z","department":[{"_id":"E-Lib"}],"ddc":["020"],"user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","file_date_updated":"2020-07-14T12:45:57Z","intvolume":"        65","month":"09","publist_id":"3754","volume":65},{"month":"06","quality_controlled":"1","publist_id":"3753","volume":12,"date_created":"2018-12-11T12:00:35Z","article_number":"7","department":[{"_id":"SyCr"}],"ddc":["570"],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file_date_updated":"2020-07-14T12:45:57Z","intvolume":"        12","author":[{"first_name":"Sylvia","full_name":"Cremer, Sylvia","last_name":"Cremer","id":"2F64EC8C-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-2193-3868"},{"first_name":"Masaki","full_name":"Suefuji, Masaki","last_name":"Suefuji"},{"first_name":"Alexandra","full_name":"Schrempf, Alexandra","last_name":"Schrempf"},{"last_name":"Heinze","full_name":"Heinze, Jürgen","first_name":"Jürgen"}],"oa":1,"_id":"2966","date_published":"2012-06-15T00:00:00Z","language":[{"iso":"eng"}],"doi":"10.1186/1472-6785-12-7","publisher":"BioMed Central","year":"2012","type":"journal_article","publication":"BMC Ecology","title":"The dynamics of male-male competition in Cardiocondyla obscurior ants","file":[{"date_updated":"2020-07-14T12:45:57Z","date_created":"2018-12-12T10:08:44Z","checksum":"03d004bdff3724fb1627e3f5004bad80","file_id":"4706","file_size":489994,"file_name":"IST-2012-94-v1+1_1472-6785-12-7.pdf","content_type":"application/pdf","relation":"main_file","access_level":"open_access","creator":"system"}],"pubrep_id":"94","citation":{"apa":"Cremer, S., Suefuji, M., Schrempf, A., &#38; Heinze, J. (2012). The dynamics of male-male competition in Cardiocondyla obscurior ants. <i>BMC Ecology</i>. BioMed Central. <a href=\"https://doi.org/10.1186/1472-6785-12-7\">https://doi.org/10.1186/1472-6785-12-7</a>","short":"S. Cremer, M. Suefuji, A. Schrempf, J. Heinze, BMC Ecology 12 (2012).","mla":"Cremer, Sylvia, et al. “The Dynamics of Male-Male Competition in Cardiocondyla Obscurior Ants.” <i>BMC Ecology</i>, vol. 12, 7, BioMed Central, 2012, doi:<a href=\"https://doi.org/10.1186/1472-6785-12-7\">10.1186/1472-6785-12-7</a>.","ista":"Cremer S, Suefuji M, Schrempf A, Heinze J. 2012. The dynamics of male-male competition in Cardiocondyla obscurior ants. BMC Ecology. 12, 7.","ama":"Cremer S, Suefuji M, Schrempf A, Heinze J. The dynamics of male-male competition in Cardiocondyla obscurior ants. <i>BMC Ecology</i>. 2012;12. doi:<a href=\"https://doi.org/10.1186/1472-6785-12-7\">10.1186/1472-6785-12-7</a>","chicago":"Cremer, Sylvia, Masaki Suefuji, Alexandra Schrempf, and Jürgen Heinze. “The Dynamics of Male-Male Competition in Cardiocondyla Obscurior Ants.” <i>BMC Ecology</i>. BioMed Central, 2012. <a href=\"https://doi.org/10.1186/1472-6785-12-7\">https://doi.org/10.1186/1472-6785-12-7</a>.","ieee":"S. Cremer, M. Suefuji, A. Schrempf, and J. Heinze, “The dynamics of male-male competition in Cardiocondyla obscurior ants,” <i>BMC Ecology</i>, vol. 12. BioMed Central, 2012."},"scopus_import":1,"has_accepted_license":"1","oa_version":"Published Version","publication_status":"published","day":"15","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"abstract":[{"lang":"eng","text":"Background: The outcome of male-male competition can be predicted from the relative fighting qualities of the opponents, which often depend on their age. In insects, freshly emerged and still sexually inactive males are morphologically indistinct from older, sexually active males. These young inactive males may thus be easy targets for older males if they cannot conceal themselves from their attacks. The ant Cardiocondyla obscurior is characterised by lethal fighting between wingless (&quot; ergatoid&quot; ) males. Here, we analyse for how long young males are defenceless after eclosion, and how early adult males can detect the presence of rival males.Results: We found that old ergatoid males consistently won fights against ergatoid males younger than two days. Old males did not differentiate between different types of unpigmented pupae several days before emergence, but had more frequent contact to ready-to-eclose pupae of female sexuals and winged males than of workers and ergatoid males. In rare cases, old ergatoid males displayed alleviated biting of pigmented ergatoid male pupae shortly before adult eclosion, as well as copulation attempts to dark pupae of female sexuals and winged males. Ergatoid male behaviour may be promoted by a closer similarity of the chemical profile of ready-to-eclose pupae to the profile of adults than that of young pupae several days prior to emergence.Conclusion: Young ergatoid males of C. obscurior would benefit greatly by hiding their identity from older, resident males, as they are highly vulnerable during the first two days of their adult lives. In contrast to the winged males of the same species, which are able to prevent ergatoid male attacks by chemical female mimicry, young ergatoids do not seem to be able to produce a protective chemical profile. Conflicts in male-male competition between ergatoid males of different age thus seem to be resolved in favour of the older males. This might represent selection at the colony level rather than the individual level. © 2012 Cremer et al.; licensee BioMed Central Ltd."}],"date_updated":"2021-01-12T07:40:07Z","status":"public"},{"publication_status":"published","oa_version":"None","day":"01","ec_funded":1,"abstract":[{"lang":"eng","text":"For programs whose data variables range over Boolean or finite domains, program verification is decidable, and this forms the basis of recent tools for software model checking. In this article, we consider algorithmic verification of programs that use Boolean variables, and in addition, access a single read-only array whose length is potentially unbounded, and whose elements range over an unbounded data domain. We show that the reachability problem, while undecidable in general, is (1) PSPACE-complete for programs in which the array-accessing for-loops are not nested, (2) decidable for a restricted class of programs with doubly nested loops. The second result establishes connections to automata and logics defining languages over data words."}],"date_updated":"2023-02-23T12:09:43Z","status":"public","publication":"ACM Transactions on Computational Logic (TOCL)","related_material":{"record":[{"relation":"earlier_version","id":"4403","status":"public"}]},"title":"Algorithmic analysis of array-accessing programs","project":[{"grant_number":"267989","call_identifier":"FP7","_id":"25EE3708-B435-11E9-9278-68D0E5697425","name":"Quantitative Reactive Modeling"},{"name":"Rigorous Systems Engineering","_id":"25832EC2-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","grant_number":"S 11407_N23"}],"citation":{"apa":"Alur, R., Cerny, P., &#38; Weinstein, S. (2012). Algorithmic analysis of array-accessing programs. <i>ACM Transactions on Computational Logic (TOCL)</i>. ACM. <a href=\"https://doi.org/10.1145/2287718.2287727\">https://doi.org/10.1145/2287718.2287727</a>","ista":"Alur R, Cerny P, Weinstein S. 2012. Algorithmic analysis of array-accessing programs. ACM Transactions on Computational Logic (TOCL). 13(3), 27.","short":"R. Alur, P. Cerny, S. Weinstein, ACM Transactions on Computational Logic (TOCL) 13 (2012).","mla":"Alur, Rajeev, et al. “Algorithmic Analysis of Array-Accessing Programs.” <i>ACM Transactions on Computational Logic (TOCL)</i>, vol. 13, no. 3, 27, ACM, 2012, doi:<a href=\"https://doi.org/10.1145/2287718.2287727\">10.1145/2287718.2287727</a>.","ama":"Alur R, Cerny P, Weinstein S. Algorithmic analysis of array-accessing programs. <i>ACM Transactions on Computational Logic (TOCL)</i>. 2012;13(3). doi:<a href=\"https://doi.org/10.1145/2287718.2287727\">10.1145/2287718.2287727</a>","chicago":"Alur, Rajeev, Pavol Cerny, and Scott Weinstein. “Algorithmic Analysis of Array-Accessing Programs.” <i>ACM Transactions on Computational Logic (TOCL)</i>. ACM, 2012. <a href=\"https://doi.org/10.1145/2287718.2287727\">https://doi.org/10.1145/2287718.2287727</a>.","ieee":"R. Alur, P. Cerny, and S. Weinstein, “Algorithmic analysis of array-accessing programs,” <i>ACM Transactions on Computational Logic (TOCL)</i>, vol. 13, no. 3. ACM, 2012."},"issue":"3","scopus_import":1,"author":[{"last_name":"Alur","full_name":"Alur, Rajeev","first_name":"Rajeev"},{"last_name":"Cerny","id":"4DCBEFFE-F248-11E8-B48F-1D18A9856A87","first_name":"Pavol","full_name":"Cerny, Pavol"},{"full_name":"Weinstein, Scott","first_name":"Scott","last_name":"Weinstein"}],"_id":"2967","date_published":"2012-08-01T00:00:00Z","language":[{"iso":"eng"}],"doi":"10.1145/2287718.2287727","publisher":"ACM","year":"2012","type":"journal_article","month":"08","quality_controlled":"1","publist_id":"3748","volume":13,"article_number":"27","date_created":"2018-12-11T12:00:36Z","acknowledgement":"This research was supported in part by the NSF Cybertrust award CNS 0524059, by the European Research Council (ERC) Advanced Investigator Grant QUAREM, and by the Austrian Science Fund (FWF) project S11402-N23.","department":[{"_id":"ToHe"}],"user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","intvolume":"        13"},{"_id":"2968","oa":1,"author":[{"first_name":"Konrad","full_name":"Lohse, Konrad","last_name":"Lohse"},{"first_name":"Nicholas H","full_name":"Barton, Nicholas H","orcid":"0000-0002-8548-5240","last_name":"Barton","id":"4880FE40-F248-11E8-B48F-1D18A9856A87"},{"first_name":"George","full_name":"Melika, George","last_name":"Melika"},{"first_name":"Graham","full_name":"Stone, Graham","last_name":"Stone"}],"date_published":"2012-09-01T00:00:00Z","year":"2012","publisher":"Wiley-Blackwell","doi":"10.1111/j.1365-294X.2012.05700.x","language":[{"iso":"eng"}],"type":"journal_article","publist_id":"3746","quality_controlled":"1","month":"09","volume":21,"acknowledgement":"This work was supported by funding from the UK Natural Environment Research Council to KL (NE/I020288/1) and GS (NE/H000038/1, NE/E014453/1, NER/B/504406/1, NER/B/S2003/00856) and a grant from the European Research Council (250152) to NB.\r\nWe thank Majide Tavakoli, Juli Pujade-Villar and Pablo-Fuentes Utrilla for contributing specimens. Mike Hickerson and three anonymous reviewers gave helpful comments on earlier versions of the manuscript. ","department":[{"_id":"NiBa"}],"date_created":"2018-12-11T12:00:36Z","intvolume":"        21","file_date_updated":"2020-07-14T12:45:57Z","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","ddc":["570","579"],"abstract":[{"lang":"eng","text":"Little is known about the stability of trophic relationships in complex natural communities over evolutionary timescales. Here, we use sequence data from 18 nuclear loci to reconstruct and compare the intraspecific histories of major Pleistocene refugial populations in the Middle East, the Balkans and Iberia in a guild of four Chalcid parasitoids (Cecidostiba fungosa, Cecidostiba semifascia, Hobbya stenonota and Mesopolobus amaenus) all attacking Cynipid oak galls. We develop a likelihood method to numerically estimate models of divergence between three populations from multilocus data. We investigate the power of this framework on simulated data, and-using triplet alignments of intronic loci-quantify the support for all possible divergence relationships between refugial populations in the four parasitoids. Although an East to West order of population divergence has highest support in all but one species, we cannot rule out alternative population tree topologies. Comparing the estimated times of population splits between species, we find that one species, M. amaenus, has a significantly older history than the rest of the guild and must have arrived in central Europe at least one glacial cycle prior to other guild members. This suggests that although all four species may share a common origin in the East, they expanded westwards into Europe at different times. © 2012 Blackwell Publishing Ltd."}],"ec_funded":1,"day":"01","oa_version":"Submitted Version","page":"4605 - 4617","publication_status":"published","date_updated":"2023-05-30T13:07:47Z","status":"public","title":"A likelihood based comparison of population histories in a parasitoid guild","file":[{"creator":"system","access_level":"open_access","relation":"main_file","content_type":"application/pdf","file_name":"IST-2014-296-v1+1_4_wasps_revised3.pdf","file_size":235820,"file_id":"5304","date_created":"2018-12-12T10:17:47Z","checksum":"c14ee4cb2a8ba9575bfd8a9bb7a883bb","date_updated":"2020-07-14T12:45:57Z"},{"access_level":"open_access","relation":"main_file","content_type":"application/pdf","creator":"system","date_created":"2018-12-12T10:17:48Z","checksum":"f00afc5b887c8222014b57375b8caece","file_id":"5305","date_updated":"2020-07-14T12:45:57Z","file_name":"IST-2014-296-v1+2_4_wasps_Supporting2.pdf","file_size":41975}],"related_material":{"record":[{"relation":"research_data","status":"public","id":"13075"}]},"publication":"Molecular Ecology","citation":{"ieee":"K. Lohse, N. H. Barton, G. Melika, and G. Stone, “A likelihood based comparison of population histories in a parasitoid guild,” <i>Molecular Ecology</i>, vol. 21, no. 18. Wiley-Blackwell, pp. 4605–4617, 2012.","chicago":"Lohse, Konrad, Nicholas H Barton, George Melika, and Graham Stone. “A Likelihood Based Comparison of Population Histories in a Parasitoid Guild.” <i>Molecular Ecology</i>. Wiley-Blackwell, 2012. <a href=\"https://doi.org/10.1111/j.1365-294X.2012.05700.x\">https://doi.org/10.1111/j.1365-294X.2012.05700.x</a>.","ama":"Lohse K, Barton NH, Melika G, Stone G. A likelihood based comparison of population histories in a parasitoid guild. <i>Molecular Ecology</i>. 2012;21(18):4605-4617. doi:<a href=\"https://doi.org/10.1111/j.1365-294X.2012.05700.x\">10.1111/j.1365-294X.2012.05700.x</a>","mla":"Lohse, Konrad, et al. “A Likelihood Based Comparison of Population Histories in a Parasitoid Guild.” <i>Molecular Ecology</i>, vol. 21, no. 18, Wiley-Blackwell, 2012, pp. 4605–17, doi:<a href=\"https://doi.org/10.1111/j.1365-294X.2012.05700.x\">10.1111/j.1365-294X.2012.05700.x</a>.","ista":"Lohse K, Barton NH, Melika G, Stone G. 2012. A likelihood based comparison of population histories in a parasitoid guild. Molecular Ecology. 21(18), 4605–4617.","short":"K. Lohse, N.H. Barton, G. Melika, G. Stone, Molecular Ecology 21 (2012) 4605–4617.","apa":"Lohse, K., Barton, N. H., Melika, G., &#38; Stone, G. (2012). A likelihood based comparison of population histories in a parasitoid guild. <i>Molecular Ecology</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1111/j.1365-294X.2012.05700.x\">https://doi.org/10.1111/j.1365-294X.2012.05700.x</a>"},"project":[{"grant_number":"250152","call_identifier":"FP7","name":"Limits to selection in biology and in evolutionary computation","_id":"25B07788-B435-11E9-9278-68D0E5697425"}],"pubrep_id":"296","has_accepted_license":"1","scopus_import":1,"issue":"18"},{"issue":"41","scopus_import":1,"project":[{"name":"Glutamaterge synaptische Übertragung und Plastizität in hippocampalen Mikroschaltkreisen","_id":"25BDE9A4-B435-11E9-9278-68D0E5697425","grant_number":"SFB-TR3-TP10B"}],"citation":{"mla":"Goswami, Sarit, et al. “Miniature IPSCs in Hippocampal Granule Cells Are Triggered by Voltage-Gated Ca^(2+) Channels via Microdomain Coupling.” <i>Journal of Neuroscience</i>, vol. 32, no. 41, Society for Neuroscience, 2012, pp. 14294–304, doi:<a href=\"https://doi.org/10.1523/JNEUROSCI.6104-11.2012\">10.1523/JNEUROSCI.6104-11.2012</a>.","short":"S. Goswami, I. Bucurenciu, P.M. Jonas, Journal of Neuroscience 32 (2012) 14294–14304.","apa":"Goswami, S., Bucurenciu, I., &#38; Jonas, P. M. (2012). Miniature IPSCs in hippocampal granule cells are triggered by voltage-gated Ca^(2+) channels via microdomain coupling. <i>Journal of Neuroscience</i>. Society for Neuroscience. <a href=\"https://doi.org/10.1523/JNEUROSCI.6104-11.2012\">https://doi.org/10.1523/JNEUROSCI.6104-11.2012</a>","ista":"Goswami S, Bucurenciu I, Jonas PM. 2012. Miniature IPSCs in hippocampal granule cells are triggered by voltage-gated Ca^(2+) channels via microdomain coupling. Journal of Neuroscience. 32(41), 14294–14304.","ama":"Goswami S, Bucurenciu I, Jonas PM. Miniature IPSCs in hippocampal granule cells are triggered by voltage-gated Ca^(2+) channels via microdomain coupling. <i>Journal of Neuroscience</i>. 2012;32(41):14294-14304. doi:<a href=\"https://doi.org/10.1523/JNEUROSCI.6104-11.2012\">10.1523/JNEUROSCI.6104-11.2012</a>","chicago":"Goswami, Sarit, Iancu Bucurenciu, and Peter M Jonas. “Miniature IPSCs in Hippocampal Granule Cells Are Triggered by Voltage-Gated Ca^(2+) Channels via Microdomain Coupling.” <i>Journal of Neuroscience</i>. Society for Neuroscience, 2012. <a href=\"https://doi.org/10.1523/JNEUROSCI.6104-11.2012\">https://doi.org/10.1523/JNEUROSCI.6104-11.2012</a>.","ieee":"S. Goswami, I. Bucurenciu, and P. M. Jonas, “Miniature IPSCs in hippocampal granule cells are triggered by voltage-gated Ca^(2+) channels via microdomain coupling,” <i>Journal of Neuroscience</i>, vol. 32, no. 41. Society for Neuroscience, pp. 14294–14304, 2012."},"external_id":{"pmid":["23055500"]},"title":"Miniature IPSCs in hippocampal granule cells are triggered by voltage-gated Ca^(2+) channels via microdomain coupling","publication":"Journal of Neuroscience","main_file_link":[{"url":"http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632771/","open_access":"1"}],"status":"public","date_updated":"2021-01-12T07:40:08Z","abstract":[{"text":"The coupling between presynaptic Ca^(2+) channels and Ca^(2+) sensors of exocytosis is a key determinant of synaptic transmission. Evoked release from parvalbumin (PV)-expressing interneurons is triggered by nanodomain coupling of P/Q-type Ca^(2+) channels, whereas release from cholecystokinin (CCK)-containing interneurons is generated by microdomain coupling of N-type channels. Nanodomain coupling has several functional advantages, including speed and efficacy of transmission. One potential disadvantage is that stochastic\r\nopening of presynaptic Ca^(2+) channels may trigger spontaneous transmitter release. We addressed this possibility in rat hippocampal\r\ngranule cells, which receive converging inputs from different inhibitory sources. Both reduction of extracellular Ca^(2+) concentration and the unselective Ca^(2+) channel blocker Cd^(2+) reduced the frequency of miniature IPSCs (mIPSCs) in granule cells by ~50%, suggesting that the opening of presynaptic Ca^(2+) channels contributes to spontaneous release. Application of the selective P/Q-type Ca^(2+) channel blocker\r\nω-agatoxin IVa had no detectable effects, whereas both the N-type blocker ω-conotoxin GVIa and the L-type blocker nimodipine reduced\r\nmIPSC frequency. Furthermore, both the fast Ca^(2+) chelator BAPTA-AM and the slow chelator EGTA-AM reduced the mIPSC frequency,\r\nsuggesting that Ca^(2+)-dependent spontaneous release is triggered by microdomain rather than nanodomain coupling. The CB_(1) receptor\r\nagonist WIN 55212-2 also decreased spontaneous release; this effect was occluded by prior application of ω-conotoxin GVIa, suggesting that a major fraction of Ca^(2+)-dependent spontaneous release was generated at the terminals of CCK-expressing interneurons. Tonic inhibition generated by spontaneous opening of presynaptic N- and L-type Ca^(2+) channels may be important for hippocampal information processing.\r\n","lang":"eng"}],"publication_status":"published","oa_version":"Submitted Version","page":"14294 - 14304","day":"10","intvolume":"        32","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","pmid":1,"acknowledgement":"This work was supported by grants from the Deutsche Forschungsgemeinschaft (TR 3/B10, Leibniz program, GSC-4 Spemann Graduate School) and the European Union (European Research Council Advanced Grant).","department":[{"_id":"PeJo"}],"date_created":"2018-12-11T12:00:36Z","volume":32,"quality_controlled":"1","publist_id":"3744","month":"10","type":"journal_article","publisher":"Society for Neuroscience","year":"2012","language":[{"iso":"eng"}],"doi":"10.1523/JNEUROSCI.6104-11.2012","date_published":"2012-10-10T00:00:00Z","oa":1,"_id":"2969","author":[{"id":"3A578F32-F248-11E8-B48F-1D18A9856A87","last_name":"Goswami","full_name":"Goswami, Sarit","first_name":"Sarit"},{"first_name":"Iancu","full_name":"Bucurenciu, Iancu","last_name":"Bucurenciu"},{"first_name":"Peter M","full_name":"Jonas, Peter M","id":"353C1B58-F248-11E8-B48F-1D18A9856A87","last_name":"Jonas","orcid":"0000-0001-5001-4804"}]},{"month":"12","quality_controlled":"1","publist_id":"3739","publication":"Current Opinion in Genetics & Development","volume":22,"title":"Investigating the principles of morphogen gradient formation: from tissues to cells","date_created":"2018-12-11T12:00:37Z","department":[{"_id":"ToBo"}],"citation":{"chicago":"Kicheva, Anna, Mark Tobias Bollenbach, Ortrud Wartlick, Frank Julicher, and Marcos Gonzalez Gaitan. “Investigating the Principles of Morphogen Gradient Formation: From Tissues to Cells.” <i>Current Opinion in Genetics &#38; Development</i>. Elsevier, 2012. <a href=\"https://doi.org/10.1016/j.gde.2012.08.004\">https://doi.org/10.1016/j.gde.2012.08.004</a>.","ieee":"A. Kicheva, M. T. Bollenbach, O. Wartlick, F. Julicher, and M. Gonzalez Gaitan, “Investigating the principles of morphogen gradient formation: from tissues to cells,” <i>Current Opinion in Genetics &#38; Development</i>, vol. 22, no. 6. Elsevier, pp. 527–532, 2012.","mla":"Kicheva, Anna, et al. “Investigating the Principles of Morphogen Gradient Formation: From Tissues to Cells.” <i>Current Opinion in Genetics &#38; Development</i>, vol. 22, no. 6, Elsevier, 2012, pp. 527–32, doi:<a href=\"https://doi.org/10.1016/j.gde.2012.08.004\">10.1016/j.gde.2012.08.004</a>.","apa":"Kicheva, A., Bollenbach, M. T., Wartlick, O., Julicher, F., &#38; Gonzalez Gaitan, M. (2012). Investigating the principles of morphogen gradient formation: from tissues to cells. <i>Current Opinion in Genetics &#38; Development</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.gde.2012.08.004\">https://doi.org/10.1016/j.gde.2012.08.004</a>","short":"A. Kicheva, M.T. Bollenbach, O. Wartlick, F. Julicher, M. Gonzalez Gaitan, Current Opinion in Genetics &#38; Development 22 (2012) 527–532.","ista":"Kicheva A, Bollenbach MT, Wartlick O, Julicher F, Gonzalez Gaitan M. 2012. Investigating the principles of morphogen gradient formation: from tissues to cells. Current Opinion in Genetics &#38; Development. 22(6), 527–532.","ama":"Kicheva A, Bollenbach MT, Wartlick O, Julicher F, Gonzalez Gaitan M. Investigating the principles of morphogen gradient formation: from tissues to cells. <i>Current Opinion in Genetics &#38; Development</i>. 2012;22(6):527-532. doi:<a href=\"https://doi.org/10.1016/j.gde.2012.08.004\">10.1016/j.gde.2012.08.004</a>"},"acknowledgement":"AK is currently supported by an MRC CDF. MGG and OW were supported by the Swiss National Science Foundation, grants from the Swiss SystemsX.ch initiative, LipidX-2008/011, an ERC advanced investigator grant and the Polish-Swiss research program.","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","issue":"6","scopus_import":1,"intvolume":"        22","author":[{"orcid":"0000-0003-4509-4998","id":"3959A2A0-F248-11E8-B48F-1D18A9856A87","last_name":"Kicheva","first_name":"Anna","full_name":"Kicheva, Anna"},{"orcid":"0000-0003-4398-476X","last_name":"Bollenbach","id":"3E6DB97A-F248-11E8-B48F-1D18A9856A87","first_name":"Mark Tobias","full_name":"Bollenbach, Mark Tobias"},{"first_name":"Ortrud","full_name":"Wartlick, Ortrud","last_name":"Wartlick"},{"first_name":"Frank","full_name":"Julicher, Frank","last_name":"Julicher"},{"first_name":"Marcos","full_name":"Gonzalez Gaitan, Marcos","last_name":"Gonzalez Gaitan"}],"_id":"2970","date_published":"2012-12-01T00:00:00Z","page":"527 - 532","oa_version":"None","publication_status":"published","day":"01","abstract":[{"lang":"eng","text":"Morphogen gradients regulate the patterning and growth of many tissues, hence a key question is how they are established and maintained during development. Theoretical descriptions have helped to explain how gradient shape is controlled by the rates of morphogen production, spreading and degradation. These effective rates have been measured using fluorescence recovery after photobleaching (FRAP) and photoactivation. To unravel which molecular events determine the effective rates, such tissue-level assays have been combined with genetic analysis, high-resolution assays, and models that take into account interactions with receptors, extracellular components and trafficking. Nevertheless, because of the natural and experimental data variability, and the underlying assumptions of transport models, it remains challenging to conclusively distinguish between cellular mechanisms."}],"language":[{"iso":"eng"}],"doi":"10.1016/j.gde.2012.08.004","publisher":"Elsevier","date_updated":"2021-01-12T07:40:09Z","year":"2012","status":"public","type":"journal_article"},{"_id":"2971","author":[{"last_name":"Zankl","first_name":"Georg","full_name":"Zankl, Georg"},{"full_name":"Haxhimusa, Yll","first_name":"Yll","last_name":"Haxhimusa"},{"first_name":"Adrian","full_name":"Ion, Adrian","last_name":"Ion","id":"29F89302-F248-11E8-B48F-1D18A9856A87"}],"abstract":[{"text":"We study the task of interactive semantic labeling of a segmentation hierarchy. To this end we propose a framework interleaving two components: an automatic labeling step, based on a Conditional Random Field whose dependencies are defined by the inclusion tree of the segmentation hierarchy, and an interaction step that integrates incremental input from a human user. Evaluated on two distinct datasets, the proposed interactive approach efficiently integrates human interventions and illustrates the advantages of structured prediction in an interactive framework. ","lang":"eng"}],"oa_version":"None","publication_status":"published","date_published":"2012-01-01T00:00:00Z","page":"11 - 20","day":"01","date_updated":"2021-01-12T07:40:10Z","publisher":"Springer","year":"2012","language":[{"iso":"eng"}],"doi":"10.1007/978-3-642-32717-9_2","type":"conference","status":"public","quality_controlled":"1","publist_id":"3737","month":"01","volume":7476,"title":"Interactive labeling of image segmentation hierarchies","citation":{"ieee":"G. Zankl, Y. Haxhimusa, and A. Ion, “Interactive labeling of image segmentation hierarchies,” presented at the Pattern Recognition, Graz, Austria, 2012, vol. 7476, pp. 11–20.","chicago":"Zankl, Georg, Yll Haxhimusa, and Adrian Ion. “Interactive Labeling of Image Segmentation Hierarchies,” 7476:11–20. Springer, 2012. <a href=\"https://doi.org/10.1007/978-3-642-32717-9_2\">https://doi.org/10.1007/978-3-642-32717-9_2</a>.","ama":"Zankl G, Haxhimusa Y, Ion A. Interactive labeling of image segmentation hierarchies. In: Vol 7476. Springer; 2012:11-20. doi:<a href=\"https://doi.org/10.1007/978-3-642-32717-9_2\">10.1007/978-3-642-32717-9_2</a>","short":"G. Zankl, Y. Haxhimusa, A. Ion, in:, Springer, 2012, pp. 11–20.","apa":"Zankl, G., Haxhimusa, Y., &#38; Ion, A. (2012). Interactive labeling of image segmentation hierarchies (Vol. 7476, pp. 11–20). Presented at the Pattern Recognition, Graz, Austria: Springer. <a href=\"https://doi.org/10.1007/978-3-642-32717-9_2\">https://doi.org/10.1007/978-3-642-32717-9_2</a>","ista":"Zankl G, Haxhimusa Y, Ion A. 2012. Interactive labeling of image segmentation hierarchies. Pattern Recognition vol. 7476, 11–20.","mla":"Zankl, Georg, et al. <i>Interactive Labeling of Image Segmentation Hierarchies</i>. Vol. 7476, Springer, 2012, pp. 11–20, doi:<a href=\"https://doi.org/10.1007/978-3-642-32717-9_2\">10.1007/978-3-642-32717-9_2</a>."},"department":[{"_id":"HeEd"}],"date_created":"2018-12-11T12:00:37Z","intvolume":"      7476","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","scopus_import":1,"conference":{"location":"Graz, Austria","start_date":"2012-08-28","end_date":"2012-08-31","name":"Pattern Recognition"}},{"has_accepted_license":"1","scopus_import":1,"project":[{"_id":"2584A770-B435-11E9-9278-68D0E5697425","name":"Modern Graph Algorithmic Techniques in Formal Verification","call_identifier":"FWF","grant_number":"P 23499-N23"},{"call_identifier":"FWF","grant_number":"S 11407_N23","_id":"25832EC2-B435-11E9-9278-68D0E5697425","name":"Rigorous Systems Engineering"},{"name":"Quantitative Graph Games: Theory and Applications","_id":"2581B60A-B435-11E9-9278-68D0E5697425","grant_number":"279307","call_identifier":"FP7"},{"name":"Microsoft Research Faculty Fellowship","_id":"2587B514-B435-11E9-9278-68D0E5697425"}],"citation":{"apa":"Chatterjee, K., &#38; Doyen, L. (2012). Energy parity games. <i>Theoretical Computer Science</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.tcs.2012.07.038\">https://doi.org/10.1016/j.tcs.2012.07.038</a>","mla":"Chatterjee, Krishnendu, and Laurent Doyen. “Energy Parity Games.” <i>Theoretical Computer Science</i>, vol. 458, Elsevier, 2012, pp. 49–60, doi:<a href=\"https://doi.org/10.1016/j.tcs.2012.07.038\">10.1016/j.tcs.2012.07.038</a>.","short":"K. Chatterjee, L. Doyen, Theoretical Computer Science 458 (2012) 49–60.","ista":"Chatterjee K, Doyen L. 2012. Energy parity games. Theoretical Computer Science. 458, 49–60.","ama":"Chatterjee K, Doyen L. Energy parity games. <i>Theoretical Computer Science</i>. 2012;458:49-60. doi:<a href=\"https://doi.org/10.1016/j.tcs.2012.07.038\">10.1016/j.tcs.2012.07.038</a>","chicago":"Chatterjee, Krishnendu, and Laurent Doyen. “Energy Parity Games.” <i>Theoretical Computer Science</i>. Elsevier, 2012. <a href=\"https://doi.org/10.1016/j.tcs.2012.07.038\">https://doi.org/10.1016/j.tcs.2012.07.038</a>.","ieee":"K. Chatterjee and L. Doyen, “Energy parity games,” <i>Theoretical Computer Science</i>, vol. 458. Elsevier, pp. 49–60, 2012."},"arxiv":1,"pubrep_id":"935","related_material":{"record":[{"relation":"earlier_version","id":"3851","status":"public"}]},"external_id":{"arxiv":["1001.5183"]},"file":[{"creator":"kschuh","access_level":"open_access","content_type":"application/pdf","relation":"main_file","file_name":"2012_Elsevier_Chatterjee.pdf","file_size":351271,"checksum":"719e4a5af5a01ad3f2f7f7f05b3c2b09","date_created":"2019-02-06T11:56:22Z","file_id":"5935","date_updated":"2020-07-14T12:45:57Z"}],"title":"Energy parity games","publication":"Theoretical Computer Science","license":"https://creativecommons.org/licenses/by-nc-nd/4.0/","status":"public","date_updated":"2023-02-23T11:45:29Z","ec_funded":1,"abstract":[{"text":"Energy parity games are infinite two-player turn-based games played on weighted graphs. The objective of the game combines a (qualitative) parity condition with the (quantitative) requirement that the sum of the weights (i.e., the level of energy in the game) must remain positive. Beside their own interest in the design and synthesis of resource-constrained omega-regular specifications, energy parity games provide one of the simplest model of games with combined qualitative and quantitative objectives. Our main results are as follows: (a) exponential memory is sufficient and may be necessary for winning strategies in energy parity games; (b) the problem of deciding the winner in energy parity games can be solved in NP ∩ coNP; and (c) we give an algorithm to solve energy parity by reduction to energy games. We also show that the problem of deciding the winner in energy parity games is logspace-equivalent to the problem of deciding the winner in mean-payoff parity games, which can thus be solved in NP ∩ coNP. As a consequence we also obtain a conceptually simple algorithm to solve mean-payoff parity games.","lang":"eng"}],"publication_status":"published","oa_version":"Published Version","page":"49 - 60","day":"02","tmp":{"image":"/images/cc_by_nc_nd.png","short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"intvolume":"       458","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","ddc":["004"],"file_date_updated":"2020-07-14T12:45:57Z","department":[{"_id":"KrCh"}],"date_created":"2018-12-11T12:00:37Z","volume":458,"quality_controlled":"1","publist_id":"3736","month":"11","type":"journal_article","publisher":"Elsevier","year":"2012","language":[{"iso":"eng"}],"doi":"10.1016/j.tcs.2012.07.038","date_published":"2012-11-02T00:00:00Z","oa":1,"_id":"2972","author":[{"id":"2E5DCA20-F248-11E8-B48F-1D18A9856A87","last_name":"Chatterjee","orcid":"0000-0002-4561-241X","full_name":"Chatterjee, Krishnendu","first_name":"Krishnendu"},{"first_name":"Laurent","full_name":"Doyen, Laurent","last_name":"Doyen"}]},{"day":"01","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"oa_version":"Submitted Version","publication_status":"published","page":"663 - 680","abstract":[{"text":"We construct a perfectly binding string commitment scheme whose security is based on the learning parity with noise (LPN) assumption, or equivalently, the hardness of decoding random linear codes. Our scheme not only allows for a simple and efficient zero-knowledge proof of knowledge for committed values (essentially a Σ-protocol), but also for such proofs showing any kind of relation amongst committed values, i.e. proving that messages m_0,...,m_u, are such that m_0=C(m_1,...,m_u) for any circuit C.\r\n\r\nTo get soundness which is exponentially small in a security parameter t, and when the zero-knowledge property relies on the LPN problem with secrets of length l, our 3 round protocol has communication complexity O(t|C|l log(l)) and computational complexity of O(t|C|l) bit operations. The hidden constants are small, and the computation consists mostly of computing inner products of bit-vectors.","lang":"eng"}],"ec_funded":1,"status":"public","date_updated":"2021-01-12T07:40:11Z","file":[{"content_type":"application/pdf","relation":"main_file","access_level":"open_access","creator":"system","date_updated":"2020-07-14T12:45:58Z","date_created":"2018-12-12T10:14:00Z","checksum":"ab879537385efc4cb4203e7ef0fea17b","file_id":"5048","file_size":482570,"file_name":"IST-2016-721-v1+1_513.pdf"}],"title":"Commitments and efficient zero knowledge proofs from learning parity with noise","editor":[{"first_name":"Xiaoyun","full_name":"Wang, Xiaoyun","last_name":"Wang"},{"last_name":"Sako","first_name":"Kazue","full_name":"Sako, Kazue"}],"scopus_import":1,"has_accepted_license":"1","alternative_title":["LNCS"],"pubrep_id":"721","citation":{"chicago":"Jain, Abhishek, Stephan Krenn, Krzysztof Z Pietrzak, and Aris Tentes. “Commitments and Efficient Zero Knowledge Proofs from Learning Parity with Noise.” edited by Xiaoyun Wang and Kazue Sako, 7658:663–80. Springer, 2012. <a href=\"https://doi.org/10.1007/978-3-642-34961-4_40\">https://doi.org/10.1007/978-3-642-34961-4_40</a>.","ieee":"A. Jain, S. Krenn, K. Z. Pietrzak, and A. Tentes, “Commitments and efficient zero knowledge proofs from learning parity with noise,” presented at the ASIACRYPT: Theory and Application of Cryptology and Information Security, Beijing, China, 2012, vol. 7658, pp. 663–680.","ista":"Jain A, Krenn S, Pietrzak KZ, Tentes A. 2012. Commitments and efficient zero knowledge proofs from learning parity with noise. ASIACRYPT: Theory and Application of Cryptology and Information Security, LNCS, vol. 7658, 663–680.","apa":"Jain, A., Krenn, S., Pietrzak, K. Z., &#38; Tentes, A. (2012). Commitments and efficient zero knowledge proofs from learning parity with noise. In X. Wang &#38; K. Sako (Eds.) (Vol. 7658, pp. 663–680). Presented at the ASIACRYPT: Theory and Application of Cryptology and Information Security, Beijing, China: Springer. <a href=\"https://doi.org/10.1007/978-3-642-34961-4_40\">https://doi.org/10.1007/978-3-642-34961-4_40</a>","mla":"Jain, Abhishek, et al. <i>Commitments and Efficient Zero Knowledge Proofs from Learning Parity with Noise</i>. Edited by Xiaoyun Wang and Kazue Sako, vol. 7658, Springer, 2012, pp. 663–80, doi:<a href=\"https://doi.org/10.1007/978-3-642-34961-4_40\">10.1007/978-3-642-34961-4_40</a>.","short":"A. Jain, S. Krenn, K.Z. Pietrzak, A. Tentes, in:, X. Wang, K. Sako (Eds.), Springer, 2012, pp. 663–680.","ama":"Jain A, Krenn S, Pietrzak KZ, Tentes A. Commitments and efficient zero knowledge proofs from learning parity with noise. In: Wang X, Sako K, eds. Vol 7658. Springer; 2012:663-680. doi:<a href=\"https://doi.org/10.1007/978-3-642-34961-4_40\">10.1007/978-3-642-34961-4_40</a>"},"project":[{"grant_number":"259668","call_identifier":"FP7","_id":"258C570E-B435-11E9-9278-68D0E5697425","name":"Provable Security for Physical Cryptography"}],"date_published":"2012-12-01T00:00:00Z","author":[{"last_name":"Jain","full_name":"Jain, Abhishek","first_name":"Abhishek"},{"orcid":"0000-0003-2835-9093","id":"329FCCF0-F248-11E8-B48F-1D18A9856A87","last_name":"Krenn","full_name":"Krenn, Stephan","first_name":"Stephan"},{"id":"3E04A7AA-F248-11E8-B48F-1D18A9856A87","last_name":"Pietrzak","orcid":"0000-0002-9139-1654","full_name":"Pietrzak, Krzysztof Z","first_name":"Krzysztof Z"},{"last_name":"Tentes","first_name":"Aris","full_name":"Tentes, Aris"}],"_id":"2974","oa":1,"type":"conference","doi":"10.1007/978-3-642-34961-4_40","language":[{"iso":"eng"}],"year":"2012","publisher":"Springer","volume":7658,"month":"12","publist_id":"3730","file_date_updated":"2020-07-14T12:45:58Z","conference":{"name":"ASIACRYPT: Theory and Application of Cryptology and Information Security","end_date":"2012-12-06","start_date":"2012-12-02","location":"Beijing, China"},"ddc":["004","005"],"user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","intvolume":"      7658","date_created":"2018-12-11T12:00:38Z","department":[{"_id":"KrPi"}],"acknowledgement":"We are grateful to Petros Mol for helpful discussions on the reduction for the hardness of the xLPN problem.\r\n"},{"abstract":[{"text":"\nGradients of the plant hormone auxin, which depend on its active intercellular transport, are crucial for the maintenance of root meristematic activity. This directional transport is largely orchestrated by a complex interaction of specific influx and efflux carriers that mediate the auxin flow into and out of cells, respectively. Besides these transport proteins, plant-specific polyphenolic compounds knownasflavonols have beenshownto act as endogenous regulators of auxin transport. However, only limited information is available on how flavonol synthesis is developmentally regulated. Using reduction-of-function and overexpression approaches in parallel, we demonstrate that the WRKY23 transcription factor is needed for proper root growth and development by stimulating the local biosynthesis of flavonols. The expression of WRKY23 itself is controlled by auxin through the AUXIN RESPONSE FACTOR 7 (ARF7) and ARF19 transcriptional response pathway. Our results suggest a model in which WRKY23 is part of a transcriptional feedback loop of auxin on its own transport through local regulation of flavonol biosynthesis.","lang":"eng"}],"date_published":"2012-01-31T00:00:00Z","page":"1554 - 1559","publication_status":"published","day":"31","_id":"3104","author":[{"last_name":"Grunewald","full_name":"Grunewald, Wim","first_name":"Wim"},{"last_name":"De Smet","first_name":"Ive","full_name":"De Smet, Ive"},{"last_name":"Lewis","first_name":"Daniel","full_name":"Lewis, Daniel R"},{"first_name":"Christian","full_name":"Löfke, Christian","last_name":"Löfke"},{"first_name":"Leentje","full_name":"Jansen, Leentje","last_name":"Jansen"},{"last_name":"Goeminne","full_name":"Goeminne, Geert","first_name":"Geert"},{"last_name":"Vanden Bossche","first_name":"Robin","full_name":"Vanden Bossche, Robin"},{"last_name":"Karimi","full_name":"Karimi, Mansour","first_name":"Mansour"},{"full_name":"De Rybel, Bert","first_name":"Bert","last_name":"De Rybel"},{"last_name":"Vanholme","full_name":"Vanholme, Bartel","first_name":"Bartel"},{"full_name":"Teichmann, Thomas","first_name":"Thomas","last_name":"Teichmann"},{"first_name":"Wout","full_name":"Boerjan, Wout","last_name":"Boerjan"},{"full_name":"Van Montagu, Marc C","first_name":"Marc","last_name":"Van Montagu"},{"first_name":"Godelieve","full_name":"Gheysen, Godelieve","last_name":"Gheysen"},{"full_name":"Muday, Gloria K","first_name":"Gloria","last_name":"Muday"},{"full_name":"Jirí Friml","first_name":"Jirí","orcid":"0000-0002-8302-7596","last_name":"Friml","id":"4159519E-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Beeckman, Tom","first_name":"Tom","last_name":"Beeckman"}],"type":"journal_article","status":"public","date_updated":"2021-01-12T07:41:05Z","publisher":"National Academy of Sciences","year":"2012","doi":"10.1073/pnas.1121134109","volume":109,"title":"Transcription factor WRKY23 assists auxin distribution patterns during Arabidopsis root development through local control on flavonol biosynthesis","publication":"PNAS","quality_controlled":0,"publist_id":"3595","month":"01","intvolume":"       109","issue":"5","extern":1,"citation":{"mla":"Grunewald, Wim, et al. “Transcription Factor WRKY23 Assists Auxin Distribution Patterns during Arabidopsis Root Development through Local Control on Flavonol Biosynthesis.” <i>PNAS</i>, vol. 109, no. 5, National Academy of Sciences, 2012, pp. 1554–59, doi:<a href=\"https://doi.org/10.1073/pnas.1121134109\">10.1073/pnas.1121134109</a>.","apa":"Grunewald, W., De Smet, I., Lewis, D., Löfke, C., Jansen, L., Goeminne, G., … Beeckman, T. (2012). Transcription factor WRKY23 assists auxin distribution patterns during Arabidopsis root development through local control on flavonol biosynthesis. <i>PNAS</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.1121134109\">https://doi.org/10.1073/pnas.1121134109</a>","ista":"Grunewald W, De Smet I, Lewis D, Löfke C, Jansen L, Goeminne G, Vanden Bossche R, Karimi M, De Rybel B, Vanholme B, Teichmann T, Boerjan W, Van Montagu M, Gheysen G, Muday G, Friml J, Beeckman T. 2012. Transcription factor WRKY23 assists auxin distribution patterns during Arabidopsis root development through local control on flavonol biosynthesis. PNAS. 109(5), 1554–1559.","short":"W. Grunewald, I. De Smet, D. Lewis, C. Löfke, L. Jansen, G. Goeminne, R. Vanden Bossche, M. Karimi, B. De Rybel, B. Vanholme, T. Teichmann, W. Boerjan, M. Van Montagu, G. Gheysen, G. Muday, J. Friml, T. Beeckman, PNAS 109 (2012) 1554–1559.","ama":"Grunewald W, De Smet I, Lewis D, et al. Transcription factor WRKY23 assists auxin distribution patterns during Arabidopsis root development through local control on flavonol biosynthesis. <i>PNAS</i>. 2012;109(5):1554-1559. doi:<a href=\"https://doi.org/10.1073/pnas.1121134109\">10.1073/pnas.1121134109</a>","chicago":"Grunewald, Wim, Ive De Smet, Daniel Lewis, Christian Löfke, Leentje Jansen, Geert Goeminne, Robin Vanden Bossche, et al. “Transcription Factor WRKY23 Assists Auxin Distribution Patterns during Arabidopsis Root Development through Local Control on Flavonol Biosynthesis.” <i>PNAS</i>. National Academy of Sciences, 2012. <a href=\"https://doi.org/10.1073/pnas.1121134109\">https://doi.org/10.1073/pnas.1121134109</a>.","ieee":"W. Grunewald <i>et al.</i>, “Transcription factor WRKY23 assists auxin distribution patterns during Arabidopsis root development through local control on flavonol biosynthesis,” <i>PNAS</i>, vol. 109, no. 5. National Academy of Sciences, pp. 1554–1559, 2012."},"date_created":"2018-12-11T12:01:24Z"},{"author":[{"last_name":"Whitford","full_name":"Whitford, Ryan","first_name":"Ryan"},{"last_name":"Fernandez","first_name":"Ana","full_name":"Fernandez, Ana"},{"last_name":"Tejos","full_name":"Tejos, Ricardo","first_name":"Ricardo"},{"last_name":"Pérez","full_name":"Pérez, Amparo Cuéllar","first_name":"Amparo"},{"last_name":"Kleine Vehn","full_name":"Kleine-Vehn, Jürgen","first_name":"Jürgen"},{"first_name":"Steffen","full_name":"Vanneste, Steffen","last_name":"Vanneste"},{"last_name":"Drozdzecki","full_name":"Drozdzecki, Andrzej","first_name":"Andrzej"},{"first_name":"Johannes","full_name":"Leitner, Johannes","last_name":"Leitner"},{"last_name":"Abas","full_name":"Abas, Lindy","first_name":"Lindy"},{"full_name":"Aerts, Maarten","first_name":"Maarten","last_name":"Aerts"},{"full_name":"Hoogewijs, Kurt","first_name":"Kurt","last_name":"Hoogewijs"},{"first_name":"Pawel","full_name":"Pawel Baster","last_name":"Baster","id":"3028BD74-F248-11E8-B48F-1D18A9856A87"},{"last_name":"De Groodt","first_name":"Ruth","full_name":"De Groodt, Ruth"},{"full_name":"Lin, Yao-Cheng","first_name":"Yao","last_name":"Lin"},{"last_name":"Storme","first_name":"Véronique","full_name":"Storme, Véronique"},{"last_name":"Van De Peer","first_name":"Yves","full_name":"Van de Peer, Yves"},{"first_name":"Tom","full_name":"Beeckman, Tom","last_name":"Beeckman"},{"first_name":"Annemieke","full_name":"Madder, Annemieke","last_name":"Madder"},{"full_name":"Devreese, Bart","first_name":"Bart","last_name":"Devreese"},{"last_name":"Luschnig","first_name":"Christian","full_name":"Luschnig, Christian"},{"orcid":"0000-0002-8302-7596","last_name":"Friml","id":"4159519E-F248-11E8-B48F-1D18A9856A87","full_name":"Jirí Friml","first_name":"Jirí"},{"last_name":"Hilson","full_name":"Hilson, Pierre","first_name":"Pierre"}],"_id":"3105","publication_status":"published","date_published":"2012-03-13T00:00:00Z","page":"678 - 685","day":"13","abstract":[{"lang":"eng","text":"Growth and development are coordinated by an array of intercellular communications. Known plant signaling molecules include phytohormones and hormone peptides. Although both classes can be implicated in the same developmental processes, little is known about the interplay between phytohormone action and peptide signaling within the cellular microenvironment. We show that genes coding for small secretory peptides, designated GOLVEN (GLV), modulate the distribution of the phytohormone auxin. The deregulation of the GLV function impairs the formation of auxin gradients and alters the reorientation of shoots and roots after a gravity stimulus. Specifically, the GLV signal modulates the trafficking dynamics of the auxin efflux carrier PIN-FORMED2 involved in root tropic responses and meristem organization. Our work links the local action of secretory peptides with phytohormone transport. Root growth factor (RGF) or GOLVEN (GLV) secreted peptides have previously been implicated in meristem regulation. Whitford et al. now show that RGF/GLV peptides induce rapid relocalization of the auxin efflux regulator PIN2, regulate auxin gradients, and modulate auxin-dependent root responses to specific stimuli."}],"doi":"10.1016/j.devcel.2012.02.002","date_updated":"2021-01-12T07:41:06Z","publisher":"Cell Press","year":"2012","status":"public","type":"journal_article","month":"03","quality_controlled":0,"publist_id":"3594","publication":"Developmental Cell","volume":22,"title":"GOLVEN secretory peptides regulate auxin carrier turnover during plant gravitropic responses","date_created":"2018-12-11T12:01:25Z","citation":{"ieee":"R. Whitford <i>et al.</i>, “GOLVEN secretory peptides regulate auxin carrier turnover during plant gravitropic responses,” <i>Developmental Cell</i>, vol. 22, no. 3. Cell Press, pp. 678–685, 2012.","chicago":"Whitford, Ryan, Ana Fernandez, Ricardo Tejos, Amparo Pérez, Jürgen Kleine Vehn, Steffen Vanneste, Andrzej Drozdzecki, et al. “GOLVEN Secretory Peptides Regulate Auxin Carrier Turnover during Plant Gravitropic Responses.” <i>Developmental Cell</i>. Cell Press, 2012. <a href=\"https://doi.org/10.1016/j.devcel.2012.02.002\">https://doi.org/10.1016/j.devcel.2012.02.002</a>.","ama":"Whitford R, Fernandez A, Tejos R, et al. GOLVEN secretory peptides regulate auxin carrier turnover during plant gravitropic responses. <i>Developmental Cell</i>. 2012;22(3):678-685. doi:<a href=\"https://doi.org/10.1016/j.devcel.2012.02.002\">10.1016/j.devcel.2012.02.002</a>","ista":"Whitford R, Fernandez A, Tejos R, Pérez A, Kleine Vehn J, Vanneste S, Drozdzecki A, Leitner J, Abas L, Aerts M, Hoogewijs K, Baster P, De Groodt R, Lin Y, Storme V, Van De Peer Y, Beeckman T, Madder A, Devreese B, Luschnig C, Friml J, Hilson P. 2012. GOLVEN secretory peptides regulate auxin carrier turnover during plant gravitropic responses. Developmental Cell. 22(3), 678–685.","short":"R. Whitford, A. Fernandez, R. Tejos, A. Pérez, J. Kleine Vehn, S. Vanneste, A. Drozdzecki, J. Leitner, L. Abas, M. Aerts, K. Hoogewijs, P. Baster, R. De Groodt, Y. Lin, V. Storme, Y. Van De Peer, T. Beeckman, A. Madder, B. Devreese, C. Luschnig, J. Friml, P. Hilson, Developmental Cell 22 (2012) 678–685.","mla":"Whitford, Ryan, et al. “GOLVEN Secretory Peptides Regulate Auxin Carrier Turnover during Plant Gravitropic Responses.” <i>Developmental Cell</i>, vol. 22, no. 3, Cell Press, 2012, pp. 678–85, doi:<a href=\"https://doi.org/10.1016/j.devcel.2012.02.002\">10.1016/j.devcel.2012.02.002</a>.","apa":"Whitford, R., Fernandez, A., Tejos, R., Pérez, A., Kleine Vehn, J., Vanneste, S., … Hilson, P. (2012). GOLVEN secretory peptides regulate auxin carrier turnover during plant gravitropic responses. <i>Developmental Cell</i>. Cell Press. <a href=\"https://doi.org/10.1016/j.devcel.2012.02.002\">https://doi.org/10.1016/j.devcel.2012.02.002</a>"},"issue":"3","extern":1,"intvolume":"        22"},{"extern":1,"issue":"4","intvolume":"        10","date_created":"2018-12-11T12:01:25Z","citation":{"ama":"Nagawa S, Xu T, Lin D, et al. ROP GTPase-dependent actin microfilaments promote PIN1 polarization by localized inhibition of clathrin-dependent endocytosis. <i>PLoS Biology</i>. 2012;10(4). doi:<a href=\"https://doi.org/10.1371/journal.pbio.1001299\">10.1371/journal.pbio.1001299</a>","apa":"Nagawa, S., Xu, T., Lin, D., Dhonukshe, P., Zhang, X., Friml, J., … Yang, Z. (2012). ROP GTPase-dependent actin microfilaments promote PIN1 polarization by localized inhibition of clathrin-dependent endocytosis. <i>PLoS Biology</i>. Public Library of Science. <a href=\"https://doi.org/10.1371/journal.pbio.1001299\">https://doi.org/10.1371/journal.pbio.1001299</a>","short":"S. Nagawa, T. Xu, D. Lin, P. Dhonukshe, X. Zhang, J. Friml, B. Scheres, Y. Fu, Z. Yang, PLoS Biology 10 (2012).","mla":"Nagawa, Shingo, et al. “ROP GTPase-Dependent Actin Microfilaments Promote PIN1 Polarization by Localized Inhibition of Clathrin-Dependent Endocytosis.” <i>PLoS Biology</i>, vol. 10, no. 4, Public Library of Science, 2012, doi:<a href=\"https://doi.org/10.1371/journal.pbio.1001299\">10.1371/journal.pbio.1001299</a>.","ista":"Nagawa S, Xu T, Lin D, Dhonukshe P, Zhang X, Friml J, Scheres B, Fu Y, Yang Z. 2012. ROP GTPase-dependent actin microfilaments promote PIN1 polarization by localized inhibition of clathrin-dependent endocytosis. PLoS Biology. 10(4).","ieee":"S. Nagawa <i>et al.</i>, “ROP GTPase-dependent actin microfilaments promote PIN1 polarization by localized inhibition of clathrin-dependent endocytosis,” <i>PLoS Biology</i>, vol. 10, no. 4. Public Library of Science, 2012.","chicago":"Nagawa, Shingo, Tongda Xu, Deshu Lin, Pankaj Dhonukshe, Xingxing Zhang, Jiří Friml, Ben Scheres, Ying Fu, and Zhenbiao Yang. “ROP GTPase-Dependent Actin Microfilaments Promote PIN1 Polarization by Localized Inhibition of Clathrin-Dependent Endocytosis.” <i>PLoS Biology</i>. Public Library of Science, 2012. <a href=\"https://doi.org/10.1371/journal.pbio.1001299\">https://doi.org/10.1371/journal.pbio.1001299</a>."},"publication":"PLoS Biology","title":"ROP GTPase-dependent actin microfilaments promote PIN1 polarization by localized inhibition of clathrin-dependent endocytosis","volume":10,"month":"04","publist_id":"3593","quality_controlled":0,"status":"public","type":"journal_article","doi":"10.1371/journal.pbio.1001299","year":"2012","date_updated":"2021-01-12T07:41:06Z","publisher":"Public Library of Science","day":"01","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"date_published":"2012-04-01T00:00:00Z","publication_status":"published","abstract":[{"text":"Cell polarization via asymmetrical distribution of structures or molecules is essential for diverse cellular functions and development of organisms, but how polarity is developmentally controlled has been poorly understood. In plants, the asymmetrical distribution of the PIN-FORMED (PIN) proteins involved in the cellular efflux of the quintessential phytohormone auxin plays a central role in developmental patterning, morphogenesis, and differential growth. Recently we showed that auxin promotes cell interdigitation by activating the Rho family ROP GTPases in leaf epidermal pavement cells. Here we found that auxin activation of the ROP2 signaling pathway regulates the asymmetric distribution of PIN1 by inhibiting its endocytosis. ROP2 inhibits PIN1 endocytosis via the accumulation of cortical actin microfilaments induced by the ROP2 effector protein RIC4. Our findings suggest a link between the developmental auxin signal and polar PIN1 distribution via Rho-dependent cytoskeletal reorganization and reveal the conservation of a design principle for cell polarization that is based on Rho GTPase-mediated inhibition of endocytosis.","lang":"eng"}],"author":[{"last_name":"Nagawa","full_name":"Nagawa, Shingo","first_name":"Shingo"},{"last_name":"Xu","first_name":"Tongda","full_name":"Xu, Tongda"},{"last_name":"Lin","full_name":"Lin, Deshu","first_name":"Deshu"},{"full_name":"Dhonukshe, Pankaj","first_name":"Pankaj","last_name":"Dhonukshe"},{"last_name":"Zhang","first_name":"Xingxing","full_name":"Zhang, Xingxing"},{"full_name":"Jirí Friml","first_name":"Jirí","id":"4159519E-F248-11E8-B48F-1D18A9856A87","last_name":"Friml","orcid":"0000-0002-8302-7596"},{"first_name":"Ben","full_name":"Scheres, Ben","last_name":"Scheres"},{"full_name":"Fu, Ying","first_name":"Ying","last_name":"Fu"},{"first_name":"Zhenbiao","full_name":"Yang, Zhenbiao","last_name":"Yang"}],"_id":"3106"},{"day":"01","page":"415 - 416","date_published":"2012-05-01T00:00:00Z","publication_status":"published","oa_version":"None","author":[{"last_name":"Vanneste","first_name":"Steffen","full_name":"Vanneste, Steffen"},{"orcid":"0000-0002-8302-7596","id":"4159519E-F248-11E8-B48F-1D18A9856A87","last_name":"Friml","full_name":"Friml, Jirí","first_name":"Jirí"}],"_id":"3107","status":"public","type":"other_academic_publication","doi":"10.1038/nchembio.943","language":[{"iso":"eng"}],"year":"2012","publisher":"Nature Publishing Group","date_updated":"2021-01-12T07:41:06Z","publication":"Nature Chemical Biology","title":"Plant signaling: Deconstructing auxin sensing","volume":8,"month":"05","publist_id":"3592","quality_controlled":"1","issue":"5","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","extern":"1","intvolume":"         8","date_created":"2018-12-11T12:01:26Z","citation":{"ama":"Vanneste S, Friml J. <i>Plant Signaling: Deconstructing Auxin Sensing</i>. Vol 8. Nature Publishing Group; 2012:415-416. doi:<a href=\"https://doi.org/10.1038/nchembio.943\">10.1038/nchembio.943</a>","apa":"Vanneste, S., &#38; Friml, J. (2012). <i>Plant signaling: Deconstructing auxin sensing</i>. <i>Nature Chemical Biology</i> (Vol. 8, pp. 415–416). Nature Publishing Group. <a href=\"https://doi.org/10.1038/nchembio.943\">https://doi.org/10.1038/nchembio.943</a>","short":"S. Vanneste, J. Friml, Plant Signaling: Deconstructing Auxin Sensing, Nature Publishing Group, 2012.","mla":"Vanneste, Steffen, and Jiří Friml. “Plant Signaling: Deconstructing Auxin Sensing.” <i>Nature Chemical Biology</i>, vol. 8, no. 5, Nature Publishing Group, 2012, pp. 415–16, doi:<a href=\"https://doi.org/10.1038/nchembio.943\">10.1038/nchembio.943</a>.","ista":"Vanneste S, Friml J. 2012. Plant signaling: Deconstructing auxin sensing, Nature Publishing Group,p.","ieee":"S. Vanneste and J. Friml, <i>Plant signaling: Deconstructing auxin sensing</i>, vol. 8, no. 5. Nature Publishing Group, 2012, pp. 415–416.","chicago":"Vanneste, Steffen, and Jiří Friml. <i>Plant Signaling: Deconstructing Auxin Sensing</i>. <i>Nature Chemical Biology</i>. Vol. 8. Nature Publishing Group, 2012. <a href=\"https://doi.org/10.1038/nchembio.943\">https://doi.org/10.1038/nchembio.943</a>."}},{"_id":"3108","author":[{"last_name":"Barbez","full_name":"Barbez, Elke","first_name":"Elke"},{"last_name":"Kubeš","full_name":"Kubeš, Martin","first_name":"Martin"},{"first_name":"Jakub","full_name":"Rolčík, Jakub","last_name":"Rolčík"},{"last_name":"Béziat","full_name":"Béziat, Chloe","first_name":"Chloe"},{"full_name":"Pěnčík, Aleš","first_name":"Aleš","last_name":"Pěnčík"},{"first_name":"Bangjun","full_name":"Wang, Bangjun","last_name":"Wang"},{"last_name":"Rosquete","first_name":"Michel","full_name":"Rosquete, Michel Ruiz"},{"last_name":"Zhu","full_name":"Zhu, Jinsheng","first_name":"Jinsheng"},{"last_name":"Dobrev","first_name":"Petre","full_name":"Dobrev, Petre I"},{"full_name":"Lee, Yuree","first_name":"Yuree","last_name":"Lee"},{"first_name":"Eva","full_name":"Zašímalová, Eva","last_name":"Zašímalová"},{"last_name":"Petrášek","first_name":"Jan","full_name":"Petrášek, Jan"},{"first_name":"Markus","full_name":"Geisler, Markus","last_name":"Geisler"},{"first_name":"Jirí","full_name":"Jirí Friml","orcid":"0000-0002-8302-7596","last_name":"Friml","id":"4159519E-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Kleine-Vehn, Jürgen","first_name":"Jürgen","last_name":"Kleine Vehn"}],"abstract":[{"text":"The phytohormone auxin acts as a prominent signal, providing, by its local accumulation or depletion in selected cells, a spatial and temporal reference for changes in the developmental program. The distribution of auxin depends on both auxin metabolism (biosynthesis, conjugation and degradation) and cellular auxin transport. We identified in silico a novel putative auxin transport facilitator family, called PIN-LIKES (PILS). Here we illustrate that PILS proteins are required for auxin-dependent regulation of plant growth by determining the cellular sensitivity to auxin. PILS proteins regulate intracellular auxin accumulation at the endoplasmic reticulum and thus auxin availability for nuclear auxin signalling. PILS activity affects the level of endogenous auxin indole-3-acetic acid (IAA), presumably via intracellular accumulation and metabolism. Our findings reveal that the transport machinery to compartmentalize auxin within the cell is of an unexpected molecular complexity and demonstrate this compartmentalization to be functionally important for a number of developmental processes.","lang":"eng"}],"day":"03","publication_status":"published","date_published":"2012-05-03T00:00:00Z","page":"119 - 122","year":"2012","publisher":"Nature Publishing Group","date_updated":"2021-01-12T07:41:07Z","doi":"10.1038/nature11001","type":"journal_article","status":"public","publist_id":"3591","quality_controlled":0,"month":"05","title":"A novel putative auxin carrier family regulates intracellular auxin homeostasis in plants","volume":485,"publication":"Nature","citation":{"mla":"Barbez, Elke, et al. “A Novel Putative Auxin Carrier Family Regulates Intracellular Auxin Homeostasis in Plants.” <i>Nature</i>, vol. 485, no. 7396, Nature Publishing Group, 2012, pp. 119–22, doi:<a href=\"https://doi.org/10.1038/nature11001\">10.1038/nature11001</a>.","ista":"Barbez E, Kubeš M, Rolčík J, Béziat C, Pěnčík A, Wang B, Rosquete M, Zhu J, Dobrev P, Lee Y, Zašímalová E, Petrášek J, Geisler M, Friml J, Kleine Vehn J. 2012. A novel putative auxin carrier family regulates intracellular auxin homeostasis in plants. Nature. 485(7396), 119–122.","short":"E. Barbez, M. Kubeš, J. Rolčík, C. Béziat, A. Pěnčík, B. Wang, M. Rosquete, J. Zhu, P. Dobrev, Y. Lee, E. Zašímalová, J. Petrášek, M. Geisler, J. Friml, J. Kleine Vehn, Nature 485 (2012) 119–122.","apa":"Barbez, E., Kubeš, M., Rolčík, J., Béziat, C., Pěnčík, A., Wang, B., … Kleine Vehn, J. (2012). A novel putative auxin carrier family regulates intracellular auxin homeostasis in plants. <i>Nature</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/nature11001\">https://doi.org/10.1038/nature11001</a>","ama":"Barbez E, Kubeš M, Rolčík J, et al. A novel putative auxin carrier family regulates intracellular auxin homeostasis in plants. <i>Nature</i>. 2012;485(7396):119-122. doi:<a href=\"https://doi.org/10.1038/nature11001\">10.1038/nature11001</a>","chicago":"Barbez, Elke, Martin Kubeš, Jakub Rolčík, Chloe Béziat, Aleš Pěnčík, Bangjun Wang, Michel Rosquete, et al. “A Novel Putative Auxin Carrier Family Regulates Intracellular Auxin Homeostasis in Plants.” <i>Nature</i>. Nature Publishing Group, 2012. <a href=\"https://doi.org/10.1038/nature11001\">https://doi.org/10.1038/nature11001</a>.","ieee":"E. Barbez <i>et al.</i>, “A novel putative auxin carrier family regulates intracellular auxin homeostasis in plants,” <i>Nature</i>, vol. 485, no. 7396. Nature Publishing Group, pp. 119–122, 2012."},"date_created":"2018-12-11T12:01:26Z","intvolume":"       485","issue":"7396","extern":1},{"_id":"3109","author":[{"full_name":"Irani, Niloufer G","first_name":"Niloufer","last_name":"Irani"},{"first_name":"Simone","full_name":"Di Rubbo, Simone","last_name":"Di Rubbo"},{"full_name":"Mylle, Evelien","first_name":"Evelien","last_name":"Mylle"},{"full_name":"Van Den Begin, Jos","first_name":"Jos","last_name":"Van Den Begin"},{"last_name":"Schneider Pizoń","first_name":"Joanna","full_name":"Schneider-Pizoń, Joanna"},{"full_name":"Hniliková, Jaroslava","first_name":"Jaroslava","last_name":"Hniliková"},{"full_name":"Šíša, Miroslav","first_name":"Miroslav","last_name":"Šíša"},{"last_name":"Buyst","full_name":"Buyst, Dieter","first_name":"Dieter"},{"last_name":"Vilarrasa Blasi","first_name":"Josep","full_name":"Vilarrasa-Blasi, Josep"},{"full_name":"Szatmári, Anna-Maria","first_name":"Anna","last_name":"Szatmári"},{"last_name":"Van Damme","first_name":"Daniël","full_name":"Van Damme, Daniël"},{"full_name":"Mishev, Kiril","first_name":"Kiril","last_name":"Mishev"},{"full_name":"Codreanu, Mirela-Corina","first_name":"Mirela","last_name":"Codreanu"},{"first_name":"Ladislav","full_name":"Kohout, Ladislav","last_name":"Kohout"},{"first_name":"Miroslav","full_name":"Strnad, Miroslav","last_name":"Strnad"},{"last_name":"Caño Delgado","full_name":"Caño-Delgado, Ana I","first_name":"Ana"},{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","last_name":"Friml","orcid":"0000-0002-8302-7596","first_name":"Jirí","full_name":"Jirí Friml"},{"last_name":"Madder","first_name":"Annemieke","full_name":"Madder, Annemieke"},{"full_name":"Russinova, Eugenia","first_name":"Eugenia","last_name":"Russinova"}],"abstract":[{"lang":"eng","text":"Receptor-mediated endocytosis is an integral part of signal transduction as it mediates signal attenuation and provides spatial and temporal dimensions to signaling events. One of the best-studied leucine-rich repeat receptor-like kinases in plants, BRASSINOSTEROID INSENSITIVE 1 (BRI1), perceives its ligand, the brassinosteroid (BR) hormone, at the cell surface and is constitutively endocytosed. However, the importance of endocytosis for BR signaling remains unclear. Here we developed a bioactive, fluorescent BR analog, Alexa Fluor 647-castasterone (AFCS), and visualized the endocytosis of BRI1-AFCS complexes in living Arabidopsis thaliana cells. Impairment of endocytosis dependent on clathrin and the guanine nucleotide exchange factor for ARF GTPases (ARF-GEF) GNOM enhanced BR signaling by retaining active BRI1-ligand complexes at the plasma membrane. Increasing the trans-Golgi network/early endosome pool of BRI1-BR complexes did not affect BR signaling. Our findings provide what is to our knowledge the first visualization of receptor-ligand complexes in plants and reveal clathrin-and ARF-GEF-dependent endocytic regulation of BR signaling from the plasma membrane."}],"day":"01","page":"583 - 589","publication_status":"published","date_published":"2012-06-01T00:00:00Z","year":"2012","date_updated":"2021-01-12T07:41:07Z","publisher":"Nature Publishing Group","doi":"10.1038/nchembio.958","type":"journal_article","status":"public","publist_id":"3590","quality_controlled":0,"month":"06","title":"Fluorescent castasterone reveals BRI1 signaling from the plasma membrane","volume":8,"publication":"Nature Chemical Biology","citation":{"chicago":"Irani, Niloufer, Simone Di Rubbo, Evelien Mylle, Jos Van Den Begin, Joanna Schneider Pizoń, Jaroslava Hniliková, Miroslav Šíša, et al. “Fluorescent Castasterone Reveals BRI1 Signaling from the Plasma Membrane.” <i>Nature Chemical Biology</i>. Nature Publishing Group, 2012. <a href=\"https://doi.org/10.1038/nchembio.958\">https://doi.org/10.1038/nchembio.958</a>.","ieee":"N. Irani <i>et al.</i>, “Fluorescent castasterone reveals BRI1 signaling from the plasma membrane,” <i>Nature Chemical Biology</i>, vol. 8, no. 6. Nature Publishing Group, pp. 583–589, 2012.","apa":"Irani, N., Di Rubbo, S., Mylle, E., Van Den Begin, J., Schneider Pizoń, J., Hniliková, J., … Russinova, E. (2012). Fluorescent castasterone reveals BRI1 signaling from the plasma membrane. <i>Nature Chemical Biology</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/nchembio.958\">https://doi.org/10.1038/nchembio.958</a>","ista":"Irani N, Di Rubbo S, Mylle E, Van Den Begin J, Schneider Pizoń J, Hniliková J, Šíša M, Buyst D, Vilarrasa Blasi J, Szatmári A, Van Damme D, Mishev K, Codreanu M, Kohout L, Strnad M, Caño Delgado A, Friml J, Madder A, Russinova E. 2012. Fluorescent castasterone reveals BRI1 signaling from the plasma membrane. Nature Chemical Biology. 8(6), 583–589.","short":"N. Irani, S. Di Rubbo, E. Mylle, J. Van Den Begin, J. Schneider Pizoń, J. Hniliková, M. Šíša, D. Buyst, J. Vilarrasa Blasi, A. Szatmári, D. Van Damme, K. Mishev, M. Codreanu, L. Kohout, M. Strnad, A. Caño Delgado, J. Friml, A. Madder, E. Russinova, Nature Chemical Biology 8 (2012) 583–589.","mla":"Irani, Niloufer, et al. “Fluorescent Castasterone Reveals BRI1 Signaling from the Plasma Membrane.” <i>Nature Chemical Biology</i>, vol. 8, no. 6, Nature Publishing Group, 2012, pp. 583–89, doi:<a href=\"https://doi.org/10.1038/nchembio.958\">10.1038/nchembio.958</a>.","ama":"Irani N, Di Rubbo S, Mylle E, et al. Fluorescent castasterone reveals BRI1 signaling from the plasma membrane. <i>Nature Chemical Biology</i>. 2012;8(6):583-589. doi:<a href=\"https://doi.org/10.1038/nchembio.958\">10.1038/nchembio.958</a>"},"date_created":"2018-12-11T12:01:26Z","intvolume":"         8","extern":1,"issue":"6"},{"day":"01","publication_status":"published","date_published":"2012-06-01T00:00:00Z","page":"2497 - 2514","abstract":[{"text":"The directional transport of the phytohormone auxin depends on the phosphorylation status and polar localization of PIN-FORMED (PIN) auxin efflux proteins. While PINIOD (PID) kinase is directly involved in the phosphorylation of PIN proteins, the phosphatase holoenzyme complexes that dephosphorylate PIN proteins remain elusive. Here, we demonstrate that mutations simultaneously disrupting the function of Arabidopsis thaliana FyPP1 (for Phytochrome-associated serine/threonine protein phosphatase1) and FyPP3, two homologous genes encoding the catalytic subunits of protein phosphatase6 (PP6), cause elevated accumulation of phosphorylated PIN proteins, correlating with a basal-to-apical shift in subcellular PIN localization. The changes in PIN polarity result in increased root basipetal auxin transport and severe defects, including shorter roots, fewer lateral roots, defective columella cells, root meristem collapse, abnormal cotyledons (small, cup-shaped, or fused cotyledons), and altered leaf venation. Our molecular, biochemical, and genetic data support the notion that FyPP1/3, SAL (for SAPS DOMAIN-LIKE), and PP2AA proteins (RCN1 [for ROOTS CURL IN NAPHTHYLPHTHALAMIC ACID1] or PP2AA1, PP2AA2, and PP2AA3) physically interact to form a novel PP6-type heterotrimeric holoenzyme complex. We also show that FyPP1/3, SAL, and PP2AA interact with a subset of PIN proteins and that for SAL the strength of the interaction depends on the PIN phosphorylation status. Thus, an Arabidopsis PP6-type phosphatase holoenzyme acts antagonistically with PID to direct auxin transport polarity and plant development by directly regulating PIN phosphorylation. ","lang":"eng"}],"author":[{"full_name":"Dai, Mingqiu","first_name":"Mingqiu","last_name":"Dai"},{"first_name":"Chen","full_name":"Zhang, Chen","last_name":"Zhang"},{"last_name":"Kania","id":"4AE5C486-F248-11E8-B48F-1D18A9856A87","first_name":"Urszula","full_name":"Urszula Kania"},{"last_name":"Chen","first_name":"Fang","full_name":"Chen, Fang"},{"first_name":"Qin","full_name":"Xue, Qin","last_name":"Xue"},{"full_name":"McCray, Tyra","first_name":"Tyra","last_name":"Mccray"},{"last_name":"Li","first_name":"Gang","full_name":"Li, Gang"},{"last_name":"Qin","full_name":"Qin, Genji","first_name":"Genji"},{"full_name":"Wakeley, Michelle","first_name":"Michelle","last_name":"Wakeley"},{"last_name":"Terzaghi","first_name":"William","full_name":"Terzaghi, William"},{"last_name":"Wan","full_name":"Wan, Jianmin","first_name":"Jianmin"},{"first_name":"Yunde","full_name":"Zhao, Yunde","last_name":"Zhao"},{"last_name":"Xu","full_name":"Xu, Jian","first_name":"Jian"},{"first_name":"Jirí","full_name":"Jirí Friml","orcid":"0000-0002-8302-7596","id":"4159519E-F248-11E8-B48F-1D18A9856A87","last_name":"Friml"},{"last_name":"Deng","first_name":"Xing","full_name":"Deng, Xing W"},{"last_name":"Wang","full_name":"Wang, Haiyang","first_name":"Haiyang"}],"_id":"3110","status":"public","type":"journal_article","doi":"10.1105/tpc.112.098905","year":"2012","publisher":"American Society of Plant Biologists","date_updated":"2021-01-12T07:41:08Z","publication":"Plant Cell","title":"A PP6 type phosphatase holoenzyme directly regulates PIN phosphorylation and auxin efflux in Arabidopsis","volume":24,"month":"06","publist_id":"3589","quality_controlled":0,"issue":"6","extern":1,"intvolume":"        24","date_created":"2018-12-11T12:01:27Z","citation":{"chicago":"Dai, Mingqiu, Chen Zhang, Urszula Kania, Fang Chen, Qin Xue, Tyra Mccray, Gang Li, et al. “A PP6 Type Phosphatase Holoenzyme Directly Regulates PIN Phosphorylation and Auxin Efflux in Arabidopsis.” <i>Plant Cell</i>. American Society of Plant Biologists, 2012. <a href=\"https://doi.org/10.1105/tpc.112.098905\">https://doi.org/10.1105/tpc.112.098905</a>.","ieee":"M. Dai <i>et al.</i>, “A PP6 type phosphatase holoenzyme directly regulates PIN phosphorylation and auxin efflux in Arabidopsis,” <i>Plant Cell</i>, vol. 24, no. 6. American Society of Plant Biologists, pp. 2497–2514, 2012.","apa":"Dai, M., Zhang, C., Kania, U., Chen, F., Xue, Q., Mccray, T., … Wang, H. (2012). A PP6 type phosphatase holoenzyme directly regulates PIN phosphorylation and auxin efflux in Arabidopsis. <i>Plant Cell</i>. American Society of Plant Biologists. <a href=\"https://doi.org/10.1105/tpc.112.098905\">https://doi.org/10.1105/tpc.112.098905</a>","short":"M. Dai, C. Zhang, U. Kania, F. Chen, Q. Xue, T. Mccray, G. Li, G. Qin, M. Wakeley, W. Terzaghi, J. Wan, Y. Zhao, J. Xu, J. Friml, X. Deng, H. Wang, Plant Cell 24 (2012) 2497–2514.","mla":"Dai, Mingqiu, et al. “A PP6 Type Phosphatase Holoenzyme Directly Regulates PIN Phosphorylation and Auxin Efflux in Arabidopsis.” <i>Plant Cell</i>, vol. 24, no. 6, American Society of Plant Biologists, 2012, pp. 2497–514, doi:<a href=\"https://doi.org/10.1105/tpc.112.098905\">10.1105/tpc.112.098905</a>.","ista":"Dai M, Zhang C, Kania U, Chen F, Xue Q, Mccray T, Li G, Qin G, Wakeley M, Terzaghi W, Wan J, Zhao Y, Xu J, Friml J, Deng X, Wang H. 2012. A PP6 type phosphatase holoenzyme directly regulates PIN phosphorylation and auxin efflux in Arabidopsis. Plant Cell. 24(6), 2497–2514.","ama":"Dai M, Zhang C, Kania U, et al. A PP6 type phosphatase holoenzyme directly regulates PIN phosphorylation and auxin efflux in Arabidopsis. <i>Plant Cell</i>. 2012;24(6):2497-2514. doi:<a href=\"https://doi.org/10.1105/tpc.112.098905\">10.1105/tpc.112.098905</a>"}},{"doi":"10.1016/j.cub.2012.05.019","year":"2012","date_updated":"2021-01-12T07:41:08Z","publisher":"Cell Press","status":"public","type":"journal_article","author":[{"full_name":"Lin, Deshu","first_name":"Deshu","last_name":"Lin"},{"last_name":"Nagawa","first_name":"Shingo","full_name":"Nagawa, Shingo"},{"first_name":"Jisheng","full_name":"Chen, Jisheng","last_name":"Chen"},{"last_name":"Cao","first_name":"Lingyan","full_name":"Cao, Lingyan"},{"last_name":"Chen","id":"4E5ADCAA-F248-11E8-B48F-1D18A9856A87","first_name":"Xu","full_name":"Xu Chen"},{"last_name":"Xu","full_name":"Xu, Tongda","first_name":"Tongda"},{"first_name":"Hongjiang","full_name":"Hongjiang Li","orcid":"0000-0001-5039-9660","last_name":"Li","id":"33CA54A6-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Dhonukshe, Pankaj","first_name":"Pankaj","last_name":"Dhonukshe"},{"full_name":"Yamamuro, Chizuko","first_name":"Chizuko","last_name":"Yamamuro"},{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","last_name":"Friml","orcid":"0000-0002-8302-7596","first_name":"Jirí","full_name":"Jirí Friml"},{"last_name":"Scheres","first_name":"Ben","full_name":"Scheres, Ben"},{"last_name":"Fu","first_name":"Ying","full_name":"Fu, Ying"},{"last_name":"Yang","full_name":"Yang, Zhenbiao","first_name":"Zhenbiao"}],"_id":"3111","day":"24","publication_status":"published","page":"1319 - 1325","date_published":"2012-07-24T00:00:00Z","abstract":[{"lang":"eng","text":"PIN-FORMED (PIN) protein-mediated auxin polar transport is critically important for development, pattern formation, and morphogenesis in plants. Auxin has been implicated in the regulation of polar auxin transport by inhibiting PIN endocytosis [1, 2], but how auxin regulates this process is poorly understood. Our genetic screen identified the Arabidopsis SPIKE1 (SPK1) gene whose loss-of-function mutations increased lateral root density and retarded gravitropic responses, as do pin2 knockout mutations [3]. SPK1 belongs to the conserved DHR2-Dock family of Rho guanine nucleotide exchange factors [4-6]. The spk1 mutations induced PIN2 internalization that was not suppressed by auxin, as did the loss-of-function mutations for Rho-like GTPase from Plants 6 (ROP6)-GTPase or its effector RIC1. Furthermore, SPK1 was required for auxin induction of ROP6 activation. Our results have established a Rho GTPase-based auxin signaling pathway that maintains PIN2 polar distribution to the plasma membrane via inhibition of its internalization in Arabidopsis roots. Our findings provide new insights into signaling mechanisms that underlie the regulation of the dynamic trafficking of PINs required for long-distance auxin transport and that link auxin signaling to PIN-mediated pattern formation and morphogenesis."}],"date_created":"2018-12-11T12:01:27Z","citation":{"mla":"Lin, Deshu, et al. “A ROP GTPase Dependent Auxin Signaling Pathway Regulates the Subcellular Distribution of PIN2 in Arabidopsis Roots.” <i>Current Biology</i>, vol. 22, no. 14, Cell Press, 2012, pp. 1319–25, doi:<a href=\"https://doi.org/10.1016/j.cub.2012.05.019\">10.1016/j.cub.2012.05.019</a>.","apa":"Lin, D., Nagawa, S., Chen, J., Cao, L., Chen, X., Xu, T., … Yang, Z. (2012). A ROP GTPase dependent auxin signaling pathway regulates the subcellular distribution of PIN2 in Arabidopsis roots. <i>Current Biology</i>. Cell Press. <a href=\"https://doi.org/10.1016/j.cub.2012.05.019\">https://doi.org/10.1016/j.cub.2012.05.019</a>","short":"D. Lin, S. Nagawa, J. Chen, L. Cao, X. Chen, T. Xu, H. Li, P. Dhonukshe, C. Yamamuro, J. Friml, B. Scheres, Y. Fu, Z. Yang, Current Biology 22 (2012) 1319–1325.","ista":"Lin D, Nagawa S, Chen J, Cao L, Chen X, Xu T, Li H, Dhonukshe P, Yamamuro C, Friml J, Scheres B, Fu Y, Yang Z. 2012. A ROP GTPase dependent auxin signaling pathway regulates the subcellular distribution of PIN2 in Arabidopsis roots. Current Biology. 22(14), 1319–1325.","ama":"Lin D, Nagawa S, Chen J, et al. A ROP GTPase dependent auxin signaling pathway regulates the subcellular distribution of PIN2 in Arabidopsis roots. <i>Current Biology</i>. 2012;22(14):1319-1325. doi:<a href=\"https://doi.org/10.1016/j.cub.2012.05.019\">10.1016/j.cub.2012.05.019</a>","chicago":"Lin, Deshu, Shingo Nagawa, Jisheng Chen, Lingyan Cao, Xu Chen, Tongda Xu, Hongjiang Li, et al. “A ROP GTPase Dependent Auxin Signaling Pathway Regulates the Subcellular Distribution of PIN2 in Arabidopsis Roots.” <i>Current Biology</i>. Cell Press, 2012. <a href=\"https://doi.org/10.1016/j.cub.2012.05.019\">https://doi.org/10.1016/j.cub.2012.05.019</a>.","ieee":"D. Lin <i>et al.</i>, “A ROP GTPase dependent auxin signaling pathway regulates the subcellular distribution of PIN2 in Arabidopsis roots,” <i>Current Biology</i>, vol. 22, no. 14. Cell Press, pp. 1319–1325, 2012."},"extern":1,"issue":"14","intvolume":"        22","month":"07","publist_id":"3588","quality_controlled":0,"publication":"Current Biology","title":"A ROP GTPase dependent auxin signaling pathway regulates the subcellular distribution of PIN2 in Arabidopsis roots","volume":22},{"year":"2012","publisher":"Cell Press","date_updated":"2021-01-12T07:41:08Z","doi":"10.1016/j.cub.2012.05.020","type":"journal_article","status":"public","_id":"3112","author":[{"first_name":"Xu","full_name":"Xu Chen","last_name":"Chen","id":"4E5ADCAA-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Naramoto","first_name":"Satoshi","full_name":"Naramoto, Satoshi"},{"last_name":"Robert","first_name":"Stéphanie","full_name":"Robert, Stéphanie"},{"last_name":"Tejos","full_name":"Tejos, Ricardo","first_name":"Ricardo"},{"full_name":"Löfke, Christian","first_name":"Christian","last_name":"Löfke"},{"last_name":"Lin","first_name":"Deshu","full_name":"Lin, Deshu"},{"last_name":"Yang","first_name":"Zhenbiao","full_name":"Yang, Zhenbiao"},{"orcid":"0000-0002-8302-7596","last_name":"Friml","id":"4159519E-F248-11E8-B48F-1D18A9856A87","full_name":"Jirí Friml","first_name":"Jirí"}],"abstract":[{"lang":"eng","text":"The dynamic spatial and temporal distribution of the crucial plant signaling molecule auxin is achieved by feedback coordination of auxin signaling and intercellular auxin transport pathways [1, 2]. Developmental roles of auxin have been attributed predominantly to its effect on transcription; however, an alternative pathway involving AUXIN BINDING PROTEIN1 (ABP1) has been proposed to regulate clathrin-mediated endocytosis in roots and Rho-like GTPase (ROP)-dependent pavement cell interdigitation in leaves [3, 4]. In this study, we show that ROP6 and its downstream effector RIC1 regulate clathrin association with the plasma membrane for clathrin-mediated endocytosis, as well as for its feedback regulation by auxin. Genetic analysis revealed that ROP6/RIC1 acts downstream of ABP1 to regulate endocytosis. This signaling circuit is also involved in the feedback regulation of PIN-FORMED 1 (PIN1) and PIN2 auxin transporters activity (via its constitutive endocytosis) and corresponding auxin transport-mediated processes, including root gravitropism and leave vascular tissue patterning. Our findings suggest that the signaling module auxin-ABP1-ROP6/RIC1-clathrin-PIN1/PIN2 is a shared component of the feedback regulation of auxin transport during both root and aerial development."}],"day":"24","publication_status":"published","date_published":"2012-07-24T00:00:00Z","page":"1326 - 1332","citation":{"chicago":"Chen, Xu, Satoshi Naramoto, Stéphanie Robert, Ricardo Tejos, Christian Löfke, Deshu Lin, Zhenbiao Yang, and Jiří Friml. “ABP1 and ROP6 GTPase Signaling Regulate Clathrin Mediated Endocytosis in Arabidopsis Roots.” <i>Current Biology</i>. Cell Press, 2012. <a href=\"https://doi.org/10.1016/j.cub.2012.05.020\">https://doi.org/10.1016/j.cub.2012.05.020</a>.","ieee":"X. Chen <i>et al.</i>, “ABP1 and ROP6 GTPase signaling regulate clathrin mediated endocytosis in Arabidopsis roots,” <i>Current Biology</i>, vol. 22, no. 14. Cell Press, pp. 1326–1332, 2012.","apa":"Chen, X., Naramoto, S., Robert, S., Tejos, R., Löfke, C., Lin, D., … Friml, J. (2012). ABP1 and ROP6 GTPase signaling regulate clathrin mediated endocytosis in Arabidopsis roots. <i>Current Biology</i>. Cell Press. <a href=\"https://doi.org/10.1016/j.cub.2012.05.020\">https://doi.org/10.1016/j.cub.2012.05.020</a>","mla":"Chen, Xu, et al. “ABP1 and ROP6 GTPase Signaling Regulate Clathrin Mediated Endocytosis in Arabidopsis Roots.” <i>Current Biology</i>, vol. 22, no. 14, Cell Press, 2012, pp. 1326–32, doi:<a href=\"https://doi.org/10.1016/j.cub.2012.05.020\">10.1016/j.cub.2012.05.020</a>.","short":"X. Chen, S. Naramoto, S. Robert, R. Tejos, C. Löfke, D. Lin, Z. Yang, J. Friml, Current Biology 22 (2012) 1326–1332.","ista":"Chen X, Naramoto S, Robert S, Tejos R, Löfke C, Lin D, Yang Z, Friml J. 2012. ABP1 and ROP6 GTPase signaling regulate clathrin mediated endocytosis in Arabidopsis roots. Current Biology. 22(14), 1326–1332.","ama":"Chen X, Naramoto S, Robert S, et al. ABP1 and ROP6 GTPase signaling regulate clathrin mediated endocytosis in Arabidopsis roots. <i>Current Biology</i>. 2012;22(14):1326-1332. doi:<a href=\"https://doi.org/10.1016/j.cub.2012.05.020\">10.1016/j.cub.2012.05.020</a>"},"date_created":"2018-12-11T12:01:27Z","intvolume":"        22","extern":1,"issue":"14","publist_id":"3587","quality_controlled":0,"month":"07","title":"ABP1 and ROP6 GTPase signaling regulate clathrin mediated endocytosis in Arabidopsis roots","volume":22,"publication":"Current Biology"}]