---
_id: '2442'
abstract:
- lang: eng
text: In a new study published in this issue of Developmental Cell, Krouk et al.
reveal a surprising mechanism by which plant root systems adapt their architecture
for soil exploitation. The dual transporter NRT1.1 uses both nitrate and the plant
hormone auxin as substrates, enabling soil nitrate availability to regulate auxin-driven
lateral root development.
author:
- first_name: Tom
full_name: Beeckman, Tom
last_name: Beeckman
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: 'Beeckman T, Friml J. Nitrate Contra Auxin: Nutrient Sensing by roots. Developmental
Cell. 2010;18(6):877-878. doi:10.1016/j.devcel.2010.05.020'
apa: 'Beeckman, T., & Friml, J. (2010). Nitrate Contra Auxin: Nutrient Sensing
by roots. Developmental Cell. Cell Press. https://doi.org/10.1016/j.devcel.2010.05.020'
chicago: 'Beeckman, Tom, and Jiří Friml. “Nitrate Contra Auxin: Nutrient Sensing
by Roots.” Developmental Cell. Cell Press, 2010. https://doi.org/10.1016/j.devcel.2010.05.020.'
ieee: 'T. Beeckman and J. Friml, “Nitrate Contra Auxin: Nutrient Sensing by roots,”
Developmental Cell, vol. 18, no. 6. Cell Press, pp. 877–878, 2010.'
ista: 'Beeckman T, Friml J. 2010. Nitrate Contra Auxin: Nutrient Sensing by roots.
Developmental Cell. 18(6), 877–878.'
mla: 'Beeckman, Tom, and Jiří Friml. “Nitrate Contra Auxin: Nutrient Sensing by
Roots.” Developmental Cell, vol. 18, no. 6, Cell Press, 2010, pp. 877–78,
doi:10.1016/j.devcel.2010.05.020.'
short: T. Beeckman, J. Friml, Developmental Cell 18 (2010) 877–878.
date_created: 2018-12-11T11:57:41Z
date_published: 2010-06-15T00:00:00Z
date_updated: 2021-01-12T06:57:31Z
day: '15'
doi: 10.1016/j.devcel.2010.05.020
extern: '1'
external_id:
pmid:
- ' 20627068'
intvolume: ' 18'
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pubmed/20627068
month: '06'
oa: 1
oa_version: Published Version
page: 877 - 878
pmid: 1
publication: Developmental Cell
publication_status: published
publisher: Cell Press
publist_id: '4461'
quality_controlled: '1'
status: public
title: 'Nitrate Contra Auxin: Nutrient Sensing by roots'
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 18
year: '2010'
...
---
_id: '2503'
abstract:
- lang: eng
text: Epilepsy is a devastating and poorly understood disease. Mutations in a secreted
neuronal protein, leucine-rich glioma inactivated 1 (LGI1), were reported in patients
with an inherited form of human epilepsy, autosomal dominant partial epilepsy
with auditory features (ADPEAF). Here, we report an essential role of LGI1 as
an antiepileptogenic ligand. We find that loss of LGI1 in mice (LGI1-/-) causes
lethal epilepsy, which is specifically rescued by the neuronal expression of LGI1
transgene, but not LGI3. Moreover, heterozygous mice for the LGI1 mutation (LGI1+/-)
show lowered seizure thresholds. Extracellularly secreted LGI1 links two epilepsy-related
receptors, ADAM22 and ADAM23, in the brain and organizes a transsynaptic protein
complex that includes presynaptic potassium channels and postsynaptic AMPA receptor
scaffolds. A lack of LGI1 disrupts this synaptic protein connection and selectively
reduces AMPA receptor-mediated synaptic transmission in the hippocampus. Thus,
LGI1 may serve as a major determinant of brain excitation, and the LGI1 gene-targeted
mouse provides a good model for human epilepsy.
author:
- first_name: Yuko
full_name: Fukata, Yuko
last_name: Fukata
- first_name: Kathryn
full_name: Lovero, Kathryn L
last_name: Lovero
- first_name: Tsuyoshi
full_name: Iwanaga, Tsuyoshi
last_name: Iwanaga
- first_name: Atsushi
full_name: Watanabe, Atsushi
last_name: Watanabe
- first_name: Norihiko
full_name: Yokoi, Norihiko
last_name: Yokoi
- first_name: Katsuhiko
full_name: Tabuchi, Katsuhiko
last_name: Tabuchi
- first_name: Ryuichi
full_name: Ryuichi Shigemoto
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Roger
full_name: Nicoll, Roger A
last_name: Nicoll
- first_name: Masaki
full_name: Fukata, Masaki
last_name: Fukata
citation:
ama: Fukata Y, Lovero K, Iwanaga T, et al. Disruption of LGI1-linked synaptic complex
causes abnormal synaptic transmission and epilepsy. PNAS. 2010;107(8):3799-3804.
doi:10.1073/pnas.0914537107
apa: Fukata, Y., Lovero, K., Iwanaga, T., Watanabe, A., Yokoi, N., Tabuchi, K.,
… Fukata, M. (2010). Disruption of LGI1-linked synaptic complex causes abnormal
synaptic transmission and epilepsy. PNAS. National Academy of Sciences.
https://doi.org/10.1073/pnas.0914537107
chicago: Fukata, Yuko, Kathryn Lovero, Tsuyoshi Iwanaga, Atsushi Watanabe, Norihiko
Yokoi, Katsuhiko Tabuchi, Ryuichi Shigemoto, Roger Nicoll, and Masaki Fukata.
“Disruption of LGI1-Linked Synaptic Complex Causes Abnormal Synaptic Transmission
and Epilepsy.” PNAS. National Academy of Sciences, 2010. https://doi.org/10.1073/pnas.0914537107.
ieee: Y. Fukata et al., “Disruption of LGI1-linked synaptic complex causes
abnormal synaptic transmission and epilepsy,” PNAS, vol. 107, no. 8. National
Academy of Sciences, pp. 3799–3804, 2010.
ista: Fukata Y, Lovero K, Iwanaga T, Watanabe A, Yokoi N, Tabuchi K, Shigemoto R,
Nicoll R, Fukata M. 2010. Disruption of LGI1-linked synaptic complex causes abnormal
synaptic transmission and epilepsy. PNAS. 107(8), 3799–3804.
mla: Fukata, Yuko, et al. “Disruption of LGI1-Linked Synaptic Complex Causes Abnormal
Synaptic Transmission and Epilepsy.” PNAS, vol. 107, no. 8, National Academy
of Sciences, 2010, pp. 3799–804, doi:10.1073/pnas.0914537107.
short: Y. Fukata, K. Lovero, T. Iwanaga, A. Watanabe, N. Yokoi, K. Tabuchi, R. Shigemoto,
R. Nicoll, M. Fukata, PNAS 107 (2010) 3799–3804.
date_created: 2018-12-11T11:58:03Z
date_published: 2010-02-23T00:00:00Z
date_updated: 2021-01-12T06:57:53Z
day: '23'
doi: 10.1073/pnas.0914537107
extern: 1
intvolume: ' 107'
issue: '8'
month: '02'
page: 3799 - 3804
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '4398'
quality_controlled: 0
status: public
title: Disruption of LGI1-linked synaptic complex causes abnormal synaptic transmission
and epilepsy
type: journal_article
volume: 107
year: '2010'
...
---
_id: '2504'
abstract:
- lang: eng
text: We present a method for immunolabeling of multiple species of membrane proteins
with high spatial resolution. It allows differentiation of equally sized very
small markers with different chemical compositions, which leads to high labeling
efficiency and reduces steric hindrance of closely spaced immunolabeled biomolecules.
Markers such as CdSe/ZnS semiconductor quantum dots and colloidal gold particles
are distinguished by differential contrast in high-angle annular detector dark-field
STEM mode or by EDX microanalysis of their elemental contents. This method was
tested by observation of labeled AMPA- and NMDA-type glutamate receptors on sodium-dodecyl-sulfate-digested
replica prepared from rat hippocampus. To improve particle visibility and detectability,
the replica films were made exclusively with carbon to avoid the high background
of conventional platinum/carbon replica. Extension of the method is suggested
by detection of 1.4 nm nanogold particles and its potential application in the
biological imaging research.
author:
- first_name: Alexandre
full_name: Loukanov, Alexandre R
last_name: Loukanov
- first_name: Naomi
full_name: Kamasawa, Naomi
last_name: Kamasawa
- first_name: Radostin
full_name: Danev, Radostin S
last_name: Danev
- first_name: Ryuichi
full_name: Ryuichi Shigemoto
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Kuniaki
full_name: Nagayama, Kuniaki
last_name: Nagayama
citation:
ama: Loukanov A, Kamasawa N, Danev R, Shigemoto R, Nagayama K. Immunolocalization
of multiple membrane proteins on a carbon replica with STEM and EDX. Ultramicroscopy.
2010;110(4):366-374. doi:10.1016/j.ultramic.2010.01.016
apa: Loukanov, A., Kamasawa, N., Danev, R., Shigemoto, R., & Nagayama, K. (2010).
Immunolocalization of multiple membrane proteins on a carbon replica with STEM
and EDX. Ultramicroscopy. Elsevier. https://doi.org/10.1016/j.ultramic.2010.01.016
chicago: Loukanov, Alexandre, Naomi Kamasawa, Radostin Danev, Ryuichi Shigemoto,
and Kuniaki Nagayama. “Immunolocalization of Multiple Membrane Proteins on a Carbon
Replica with STEM and EDX.” Ultramicroscopy. Elsevier, 2010. https://doi.org/10.1016/j.ultramic.2010.01.016.
ieee: A. Loukanov, N. Kamasawa, R. Danev, R. Shigemoto, and K. Nagayama, “Immunolocalization
of multiple membrane proteins on a carbon replica with STEM and EDX,” Ultramicroscopy,
vol. 110, no. 4. Elsevier, pp. 366–374, 2010.
ista: Loukanov A, Kamasawa N, Danev R, Shigemoto R, Nagayama K. 2010. Immunolocalization
of multiple membrane proteins on a carbon replica with STEM and EDX. Ultramicroscopy.
110(4), 366–374.
mla: Loukanov, Alexandre, et al. “Immunolocalization of Multiple Membrane Proteins
on a Carbon Replica with STEM and EDX.” Ultramicroscopy, vol. 110, no.
4, Elsevier, 2010, pp. 366–74, doi:10.1016/j.ultramic.2010.01.016.
short: A. Loukanov, N. Kamasawa, R. Danev, R. Shigemoto, K. Nagayama, Ultramicroscopy
110 (2010) 366–374.
date_created: 2018-12-11T11:58:03Z
date_published: 2010-03-01T00:00:00Z
date_updated: 2021-01-12T06:57:53Z
day: '01'
doi: 10.1016/j.ultramic.2010.01.016
extern: 1
intvolume: ' 110'
issue: '4'
month: '03'
page: 366 - 374
publication: Ultramicroscopy
publication_status: published
publisher: Elsevier
publist_id: '4397'
quality_controlled: 0
status: public
title: Immunolocalization of multiple membrane proteins on a carbon replica with STEM
and EDX
type: journal_article
volume: 110
year: '2010'
...
---
_id: '2505'
abstract:
- lang: eng
text: Cbln1, secreted from cerebellar granule cells, and the orphan glutamate receptor
52 (GluD2), expressed by Purkinje cells, are essential for synapse integrity between
these neurons in adult mice. Nevertheless, no endogenous binding partners for
these molecules have been identified. We found that Cblnl binds directly to the
N-terminal domain of GluD2. GluD2 expression by postsynaptic cells, combined with
exogenously applied Cbln1, was necessary and sufficient to induce new synapses
in vitro and in the adult cerebellum in vivo. Further, beads coated with recombinant
Cbln1 directly induced presynaptic differentiation and indirectly caused clustering
of postsynaptic molecules via GluD2. These results indicate that the Cbln1-GluD2
complex is a unique synapse organizer that acts bidirectionally on both pre- and
postsynaptic components.
author:
- first_name: Keiko
full_name: Matsuda, Keiko
last_name: Matsuda
- first_name: Eriko
full_name: Miura, Eriko
last_name: Miura
- first_name: Taisuke
full_name: Miyazaki, Taisuke
last_name: Miyazaki
- first_name: Wataru
full_name: Kakegawa, Wataru
last_name: Kakegawa
- first_name: Kyoichi
full_name: Emi, Kyoichi
last_name: Emi
- first_name: Sakae
full_name: Narumi, Sakae
last_name: Narumi
- first_name: Yugo
full_name: Fukazawa, Yugo
last_name: Fukazawa
- first_name: Aya
full_name: Ito-lshida, Aya
last_name: Ito Lshida
- first_name: Tetsuro
full_name: Kondo, Tetsuro
last_name: Kondo
- first_name: Ryuichi
full_name: Ryuichi Shigemoto
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Masahiko
full_name: Watanabe, Masahiko
last_name: Watanabe
- first_name: Michisuke
full_name: Yuzaki, Michisuke
last_name: Yuzaki
citation:
ama: Matsuda K, Miura E, Miyazaki T, et al. Cbln1 is a ligand for an orphan glutamate
receptor δ2, a bidirectional synapse organizer. Science. 2010;328(5976):363-368.
doi:10.1126/science.1185152
apa: Matsuda, K., Miura, E., Miyazaki, T., Kakegawa, W., Emi, K., Narumi, S., …
Yuzaki, M. (2010). Cbln1 is a ligand for an orphan glutamate receptor δ2, a bidirectional
synapse organizer. Science. American Association for the Advancement of
Science. https://doi.org/10.1126/science.1185152
chicago: Matsuda, Keiko, Eriko Miura, Taisuke Miyazaki, Wataru Kakegawa, Kyoichi
Emi, Sakae Narumi, Yugo Fukazawa, et al. “Cbln1 Is a Ligand for an Orphan Glutamate
Receptor Δ2, a Bidirectional Synapse Organizer.” Science. American Association
for the Advancement of Science, 2010. https://doi.org/10.1126/science.1185152.
ieee: K. Matsuda et al., “Cbln1 is a ligand for an orphan glutamate receptor
δ2, a bidirectional synapse organizer,” Science, vol. 328, no. 5976. American
Association for the Advancement of Science, pp. 363–368, 2010.
ista: Matsuda K, Miura E, Miyazaki T, Kakegawa W, Emi K, Narumi S, Fukazawa Y, Ito
Lshida A, Kondo T, Shigemoto R, Watanabe M, Yuzaki M. 2010. Cbln1 is a ligand
for an orphan glutamate receptor δ2, a bidirectional synapse organizer. Science.
328(5976), 363–368.
mla: Matsuda, Keiko, et al. “Cbln1 Is a Ligand for an Orphan Glutamate Receptor
Δ2, a Bidirectional Synapse Organizer.” Science, vol. 328, no. 5976, American
Association for the Advancement of Science, 2010, pp. 363–68, doi:10.1126/science.1185152.
short: K. Matsuda, E. Miura, T. Miyazaki, W. Kakegawa, K. Emi, S. Narumi, Y. Fukazawa,
A. Ito Lshida, T. Kondo, R. Shigemoto, M. Watanabe, M. Yuzaki, Science 328 (2010)
363–368.
date_created: 2018-12-11T11:58:04Z
date_published: 2010-04-16T00:00:00Z
date_updated: 2021-01-12T06:57:53Z
day: '16'
doi: 10.1126/science.1185152
extern: 1
intvolume: ' 328'
issue: '5976'
month: '04'
page: 363 - 368
publication: Science
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '4396'
quality_controlled: 0
status: public
title: Cbln1 is a ligand for an orphan glutamate receptor δ2, a bidirectional synapse
organizer
type: journal_article
volume: 328
year: '2010'
...
---
_id: '2506'
abstract:
- lang: eng
text: Subepithelial fibroblasts of the intestinal villi, which form a contractile
cellular network beneath the epithelium, are in close contact with epithelial
cells, nerve varicosities, capillaries, smooth muscles and immune cells, and secrete
extracellular matrix molecules, growth factors and cytokines, etc. Cultured subepithelial
fibroblasts of the rat duodenal villi display various receptors such as endothelins,
ATP, substance-P and bradykinin, and release ATP in response to mechanical stimulation.
In this study, the presence of functional NK1 receptors (NK1R) was pharmacologically
confirmed in primary culture by Ca 2+ measurement, and the effects of substance-P
were measured in an acute preparation of epithelium-free duodenal villi from 2-
to 3-week-old rats using a two-photon laser microscope. Substance-P elicited an
increase in the intracellular Ca 2+ concentration and contraction of the subepithelial
fibroblasts in culture and the isolated villi. The localization of NK1R and substance-P
in the villi was examined by light and electron microscopic immunohistochemistry.
NK1R-like immunoreactivity was intensely localized on the plasma membrane of villous
subepithelial fibroblasts in 10-day- to 4-week-old rats and mice and was decreased
or absent in adulthood. The pericryptal fibroblasts of the small and large intestine
were NK1R immuno-negative. These villous subepithelial fibroblasts form synapse-like
structures with both substance-P-immunopositive and -immunonegative nerve varicosities.
Here, we propose that the mutual interaction between villous subepithelial fibroblasts
and afferent neurons via substance-P and ATP plays important roles in the maturation
of the structure and function of the small intestine.
author:
- first_name: Sonoko
full_name: Furuya, Sonoko
last_name: Furuya
- first_name: Kishio
full_name: Furuya, Kishio
last_name: Furuya
- first_name: Ryuichi
full_name: Ryuichi Shigemoto
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Masahiro
full_name: Sokabe, Masahiro
last_name: Sokabe
citation:
ama: Furuya S, Furuya K, Shigemoto R, Sokabe M. Localization of NK1 receptors and
roles of substance-P in subepithelial fibroblasts of rat intestinal villi. Cell
and Tissue Research. 2010;342(2):243-259. doi:10.1007/s00441-010-1056-7
apa: Furuya, S., Furuya, K., Shigemoto, R., & Sokabe, M. (2010). Localization
of NK1 receptors and roles of substance-P in subepithelial fibroblasts of rat
intestinal villi. Cell and Tissue Research. Springer. https://doi.org/10.1007/s00441-010-1056-7
chicago: Furuya, Sonoko, Kishio Furuya, Ryuichi Shigemoto, and Masahiro Sokabe.
“Localization of NK1 Receptors and Roles of Substance-P in Subepithelial Fibroblasts
of Rat Intestinal Villi.” Cell and Tissue Research. Springer, 2010. https://doi.org/10.1007/s00441-010-1056-7.
ieee: S. Furuya, K. Furuya, R. Shigemoto, and M. Sokabe, “Localization of NK1 receptors
and roles of substance-P in subepithelial fibroblasts of rat intestinal villi,”
Cell and Tissue Research, vol. 342, no. 2. Springer, pp. 243–259, 2010.
ista: Furuya S, Furuya K, Shigemoto R, Sokabe M. 2010. Localization of NK1 receptors
and roles of substance-P in subepithelial fibroblasts of rat intestinal villi.
Cell and Tissue Research. 342(2), 243–259.
mla: Furuya, Sonoko, et al. “Localization of NK1 Receptors and Roles of Substance-P
in Subepithelial Fibroblasts of Rat Intestinal Villi.” Cell and Tissue Research,
vol. 342, no. 2, Springer, 2010, pp. 243–59, doi:10.1007/s00441-010-1056-7.
short: S. Furuya, K. Furuya, R. Shigemoto, M. Sokabe, Cell and Tissue Research 342
(2010) 243–259.
date_created: 2018-12-11T11:58:04Z
date_published: 2010-11-01T00:00:00Z
date_updated: 2021-01-12T06:57:54Z
day: '01'
doi: 10.1007/s00441-010-1056-7
extern: 1
intvolume: ' 342'
issue: '2'
month: '11'
page: 243 - 259
publication: Cell and Tissue Research
publication_status: published
publisher: Springer
publist_id: '4395'
quality_controlled: 0
status: public
title: Localization of NK1 receptors and roles of substance-P in subepithelial fibroblasts
of rat intestinal villi
type: journal_article
volume: 342
year: '2010'
...
---
_id: '2507'
abstract:
- lang: eng
text: T-type calcium channels play a pivotal role in regulating neural membrane
excitability in the nervous system. However, the precise subcellular distributions
of T-type channel subunits and their implication for membrane excitability are
not well understood. Here we investigated the subcellular distribution of the
α1G subunit of the calcium channel which is expressed highly in the mouse dorsal
lateral geniculate nucleus (dLGN). Light microscopic analysis demonstrated that
dLGN exhibits intense immunoperoxidase reactivity for the α1G subunit. Electron
microscopic observation showed that the labeling was present in both the relay
cells and interneurons and was found in the somatodendritic, but not axonal, domains
of these cells. Most of the immunogold particles for the α1G subunit were either
associated with the plasma membrane or the intracellular membranes. Reconstruction
analysis of serial electron microscopic images revealed that the intensity of
the intracellular labeling exhibited a gradient such that the labeling density
was higher in the proximal dendrite and progressively decreased towards the distal
dendrite. In contrast, the plasma membrane-associated particles were distributed
with a uniform density over the somatodendritic surface of dLGN cells. The labeling
density in the relay cell plasma membrane was about 3-fold higher than that of
the interneurons. These results provide ultrastructural evidence for cell-type-specific
expression levels and for uniform expression density of the α1G subunit over the
plasma membrane of dLGN cells.
author:
- first_name: Laxmi
full_name: Parajuli, Laxmi K
last_name: Parajuli
- first_name: Yugo
full_name: Fukazawa, Yugo
last_name: Fukazawa
- first_name: Masahiko
full_name: Watanabe, Masahiko
last_name: Watanabe
- first_name: Ryuichi
full_name: Ryuichi Shigemoto
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
citation:
ama: Parajuli L, Fukazawa Y, Watanabe M, Shigemoto R. Subcellular distribution of
α1G subunit of T-type calcium channel in the mouse dorsal lateral geniculate nucleus.
Journal of Comparative Neurology. 2010;518(21):4362-4374. doi:10.1002/cne.22461
apa: Parajuli, L., Fukazawa, Y., Watanabe, M., & Shigemoto, R. (2010). Subcellular
distribution of α1G subunit of T-type calcium channel in the mouse dorsal lateral
geniculate nucleus. Journal of Comparative Neurology. Wiley-Blackwell.
https://doi.org/10.1002/cne.22461
chicago: Parajuli, Laxmi, Yugo Fukazawa, Masahiko Watanabe, and Ryuichi Shigemoto.
“Subcellular Distribution of Α1G Subunit of T-Type Calcium Channel in the Mouse
Dorsal Lateral Geniculate Nucleus.” Journal of Comparative Neurology. Wiley-Blackwell,
2010. https://doi.org/10.1002/cne.22461.
ieee: L. Parajuli, Y. Fukazawa, M. Watanabe, and R. Shigemoto, “Subcellular distribution
of α1G subunit of T-type calcium channel in the mouse dorsal lateral geniculate
nucleus,” Journal of Comparative Neurology, vol. 518, no. 21. Wiley-Blackwell,
pp. 4362–4374, 2010.
ista: Parajuli L, Fukazawa Y, Watanabe M, Shigemoto R. 2010. Subcellular distribution
of α1G subunit of T-type calcium channel in the mouse dorsal lateral geniculate
nucleus. Journal of Comparative Neurology. 518(21), 4362–4374.
mla: Parajuli, Laxmi, et al. “Subcellular Distribution of Α1G Subunit of T-Type
Calcium Channel in the Mouse Dorsal Lateral Geniculate Nucleus.” Journal of
Comparative Neurology, vol. 518, no. 21, Wiley-Blackwell, 2010, pp. 4362–74,
doi:10.1002/cne.22461.
short: L. Parajuli, Y. Fukazawa, M. Watanabe, R. Shigemoto, Journal of Comparative
Neurology 518 (2010) 4362–4374.
date_created: 2018-12-11T11:58:04Z
date_published: 2010-11-01T00:00:00Z
date_updated: 2021-01-12T06:57:54Z
day: '01'
doi: 10.1002/cne.22461
extern: 1
intvolume: ' 518'
issue: '21'
month: '11'
page: 4362 - 4374
publication: Journal of Comparative Neurology
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4394'
quality_controlled: 0
status: public
title: Subcellular distribution of α1G subunit of T-type calcium channel in the mouse
dorsal lateral geniculate nucleus
type: journal_article
volume: 518
year: '2010'
...
---
_id: '2508'
abstract:
- lang: eng
text: 'The activity patterns of subthalamic nucleus (STN) neurons are intimately
linked to motor function and dysfunction and arise through the complex interaction
of intrinsic properties and inhibitory and excitatory synaptic inputs. In many
neurons, hyperpolarization-activated cyclic nucleotide-gated (HCN) channels play
key roles in intrinsic excitability and synaptic integration both under normal
conditions and in disease states. However, in STN neurons, which strongly express
HCN channels, their roles remain relatively obscure. To address this deficit,
complementary molecular and cellular electrophysiological, imaging, and computational
approaches were applied to the rat STN. Molecular profiling demonstrated that
individual STN neurons express mRNA encoding several HCN subunits, with HCN2 and
3 being the most abundant. Light and electron microscopic analysis showed that
HCN2 subunits are strongly expressed and distributed throughout the somatodendritic
plasma membrane. Voltage-, current-, and dynamic-clamp analysis, two-photon Ca
2+ imaging, and computational modeling revealed that HCN channels are activated
by GABA A receptor-mediated inputs and thus limit synaptic hyperpolarization and
deinactivation of low-voltage-activated Ca 2+ channels. Although HCN channels
also limited the temporal summation of EPSPs, generated through two-photon uncaging
of glutamate, this action was largely shunted by GABAergic inhibition that was
necessary for HCN channel activation. Together the data demonstrate that HCN channels
in STN neurons selectively counteract GABA A receptor-mediated inhibition arising
from the globus pallidus and thus promote single-spike activity rather than rebound
burst firing. '
author:
- first_name: Jeremy
full_name: Atherton, Jeremy F
last_name: Atherton
- first_name: Katsunori
full_name: Kitano, Katsunori
last_name: Kitano
- first_name: Jérôme
full_name: Baufreton, Jérôme
last_name: Baufreton
- first_name: Kai
full_name: Fan, Kai
last_name: Fan
- first_name: David
full_name: Wokosin, David L
last_name: Wokosin
- first_name: Tatiana
full_name: Tkatch, Tatiana
last_name: Tkatch
- first_name: Ryuichi
full_name: Ryuichi Shigemoto
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: James
full_name: Surmeier, James D
last_name: Surmeier
- first_name: Mark
full_name: Bevan, Mark D
last_name: Bevan
citation:
ama: Atherton J, Kitano K, Baufreton J, et al. Selective participation of somatodendritic
HCN channels in inhibitory but not excitatory synaptic integration in neurons
of the subthalamic nucleus. Journal of Neuroscience. 2010;30(47):16025-16040.
doi:10.1523/JNEUROSCI.3898-10.2010
apa: Atherton, J., Kitano, K., Baufreton, J., Fan, K., Wokosin, D., Tkatch, T.,
… Bevan, M. (2010). Selective participation of somatodendritic HCN channels in
inhibitory but not excitatory synaptic integration in neurons of the subthalamic
nucleus. Journal of Neuroscience. Society for Neuroscience. https://doi.org/10.1523/JNEUROSCI.3898-10.2010
chicago: Atherton, Jeremy, Katsunori Kitano, Jérôme Baufreton, Kai Fan, David Wokosin,
Tatiana Tkatch, Ryuichi Shigemoto, James Surmeier, and Mark Bevan. “Selective
Participation of Somatodendritic HCN Channels in Inhibitory but Not Excitatory
Synaptic Integration in Neurons of the Subthalamic Nucleus.” Journal of Neuroscience.
Society for Neuroscience, 2010. https://doi.org/10.1523/JNEUROSCI.3898-10.2010.
ieee: J. Atherton et al., “Selective participation of somatodendritic HCN
channels in inhibitory but not excitatory synaptic integration in neurons of the
subthalamic nucleus,” Journal of Neuroscience, vol. 30, no. 47. Society
for Neuroscience, pp. 16025–16040, 2010.
ista: Atherton J, Kitano K, Baufreton J, Fan K, Wokosin D, Tkatch T, Shigemoto R,
Surmeier J, Bevan M. 2010. Selective participation of somatodendritic HCN channels
in inhibitory but not excitatory synaptic integration in neurons of the subthalamic
nucleus. Journal of Neuroscience. 30(47), 16025–16040.
mla: Atherton, Jeremy, et al. “Selective Participation of Somatodendritic HCN Channels
in Inhibitory but Not Excitatory Synaptic Integration in Neurons of the Subthalamic
Nucleus.” Journal of Neuroscience, vol. 30, no. 47, Society for Neuroscience,
2010, pp. 16025–40, doi:10.1523/JNEUROSCI.3898-10.2010.
short: J. Atherton, K. Kitano, J. Baufreton, K. Fan, D. Wokosin, T. Tkatch, R. Shigemoto,
J. Surmeier, M. Bevan, Journal of Neuroscience 30 (2010) 16025–16040.
date_created: 2018-12-11T11:58:05Z
date_published: 2010-11-24T00:00:00Z
date_updated: 2021-01-12T06:57:54Z
day: '24'
doi: 10.1523/JNEUROSCI.3898-10.2010
extern: 1
intvolume: ' 30'
issue: '47'
month: '11'
page: 16025 - 16040
publication: Journal of Neuroscience
publication_status: published
publisher: Society for Neuroscience
publist_id: '4393'
quality_controlled: 0
status: public
title: Selective participation of somatodendritic HCN channels in inhibitory but not
excitatory synaptic integration in neurons of the subthalamic nucleus
type: journal_article
volume: 30
year: '2010'
...
---
_id: '2509'
abstract:
- lang: eng
text: Hippocampal CA1 pyramidal cells, which receive γ-aminobutyric acid (GABA)ergic
input from at least 18 types of presynaptic neuron, express 14 subunits of the
pentameric GABAA receptor. The relative contribution of any subunit to synaptic
and extrasynaptic receptors influences the dynamics of GABA and drug actions.
Synaptic receptors mediate phasic GABA-evoked conductance and extrasynaptic receptors
contribute to a tonic conductance. We used freeze-fracture replica-immunogold
labelling, a sensitive quantitative immunocytochemical method, to detect synaptic
and extrasynaptic pools of the alpha1, alpha2 and beta3 subunits. Antibodies to
the cytoplasmic loop of the subunits showed immunogold particles concentrated
on distinct clusters of intramembrane particles (IMPs) on the cytoplasmic face
of the plasma membrane on the somata, dendrites and axon initial segments, with
an abrupt decrease in labelling at the edge of the IMP cluster. Neuroligin-2,
a GABAergic synapse-specific adhesion molecule, co-labels all beta3 subunit-rich
IMP clusters, therefore we considered them synapses. Double-labelling for two
subunits showed that virtually all somatic synapses contain the alpha1, alpha2
and beta3 subunits. The extrasynaptic plasma membrane of the somata, dendrites
and dendritic spines showed low-density immunolabelling. Synaptic labelling densities
on somata for the alpha1, alpha2 and beta3 subunits were 78-132, 94 and 79 times
higher than on the extrasynaptic membranes, respectively. As GABAergic synapses
occupy 0.72% of the soma surface, the fraction of synaptic labelling was 33-48
(alpha1), 40 (alpha2) and 36 (beta3)% of the total somatic surface immunolabelling.
Assuming similar antibody access to all receptors, about 60% of these subunits
are in extrasynaptic receptors.
author:
- first_name: Yu
full_name: Kasugai, Yu
last_name: Kasugai
- first_name: Jerome
full_name: Swinny, Jerome D
last_name: Swinny
- first_name: John
full_name: Roberts, John D
last_name: Roberts
- first_name: Yannis
full_name: Dalezios, Yannis
last_name: Dalezios
- first_name: Yugo
full_name: Fukazawa, Yugo
last_name: Fukazawa
- first_name: Werner
full_name: Sieghart, Werner C
last_name: Sieghart
- first_name: Ryuichi
full_name: Ryuichi Shigemoto
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Péter
full_name: Somogyi, Péter
last_name: Somogyi
citation:
ama: Kasugai Y, Swinny J, Roberts J, et al. Quantitative localisation of synaptic
and extrasynaptic GABAA receptor subunits on hippocampal pyramidal cells by freeze-fracture
replica immunolabelling. European Journal of Neuroscience. 2010;32(11):1868-1888.
doi:10.1111/j.1460-9568.2010.07473.x
apa: Kasugai, Y., Swinny, J., Roberts, J., Dalezios, Y., Fukazawa, Y., Sieghart,
W., … Somogyi, P. (2010). Quantitative localisation of synaptic and extrasynaptic
GABAA receptor subunits on hippocampal pyramidal cells by freeze-fracture replica
immunolabelling. European Journal of Neuroscience. Wiley-Blackwell. https://doi.org/10.1111/j.1460-9568.2010.07473.x
chicago: Kasugai, Yu, Jerome Swinny, John Roberts, Yannis Dalezios, Yugo Fukazawa,
Werner Sieghart, Ryuichi Shigemoto, and Péter Somogyi. “Quantitative Localisation
of Synaptic and Extrasynaptic GABAA Receptor Subunits on Hippocampal Pyramidal
Cells by Freeze-Fracture Replica Immunolabelling.” European Journal of Neuroscience.
Wiley-Blackwell, 2010. https://doi.org/10.1111/j.1460-9568.2010.07473.x.
ieee: Y. Kasugai et al., “Quantitative localisation of synaptic and extrasynaptic
GABAA receptor subunits on hippocampal pyramidal cells by freeze-fracture replica
immunolabelling,” European Journal of Neuroscience, vol. 32, no. 11. Wiley-Blackwell,
pp. 1868–1888, 2010.
ista: Kasugai Y, Swinny J, Roberts J, Dalezios Y, Fukazawa Y, Sieghart W, Shigemoto
R, Somogyi P. 2010. Quantitative localisation of synaptic and extrasynaptic GABAA
receptor subunits on hippocampal pyramidal cells by freeze-fracture replica immunolabelling.
European Journal of Neuroscience. 32(11), 1868–1888.
mla: Kasugai, Yu, et al. “Quantitative Localisation of Synaptic and Extrasynaptic
GABAA Receptor Subunits on Hippocampal Pyramidal Cells by Freeze-Fracture Replica
Immunolabelling.” European Journal of Neuroscience, vol. 32, no. 11, Wiley-Blackwell,
2010, pp. 1868–88, doi:10.1111/j.1460-9568.2010.07473.x.
short: Y. Kasugai, J. Swinny, J. Roberts, Y. Dalezios, Y. Fukazawa, W. Sieghart,
R. Shigemoto, P. Somogyi, European Journal of Neuroscience 32 (2010) 1868–1888.
date_created: 2018-12-11T11:58:05Z
date_published: 2010-11-14T00:00:00Z
date_updated: 2021-01-12T06:57:55Z
day: '14'
doi: 10.1111/j.1460-9568.2010.07473.x
extern: 1
intvolume: ' 32'
issue: '11'
month: '11'
page: 1868 - 1888
publication: European Journal of Neuroscience
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4392'
quality_controlled: 0
status: public
title: Quantitative localisation of synaptic and extrasynaptic GABAA receptor subunits
on hippocampal pyramidal cells by freeze-fracture replica immunolabelling
type: journal_article
volume: 32
year: '2010'
...
---
_id: '2510'
abstract:
- lang: eng
text: Neurons in the laterocapsular division of the central nucleus of the amygdala
(CeC), which is known as the "nociceptive amygdala," receive glutamatergic
inputs from the parabrachial nucleus (PB) and the basolateral nucleus of amygdala
(BLA), which convey nociceptive information from the dorsal horn of the spinal
cord and polymodal information from the thalamus and cortex, respectively. Here,
we examined the ultrastructural properties of PB- and BLA-CeC synapses identified
with EGFP-expressing lentivirus in rats. In addition, the density of synaptic
AMPA receptors (AMPARs) on CeC neurons was studied by using highly sensitive SDS-digested
freeze-fracture replica labeling (SDS-FRL). Afferents from the PB made asymmetrical
synapses mainly on dendritic shafts (88%), whereas those from the BLA were on
dendritic spines (81%). PB-CeC synapses in dendritic shafts were significantly
larger (median 0.072 μm 2) than BLA-CeC synapses in spines (median 0.058 μm 2;
P = 0.02). The dendritic shafts that made synapses with PB fibers were also significantly
larger than those that made synapses with BLA fibers, indicating that the PB fibers
make synapses on more proximal parts of dendrites than the BLA fibers. SDS-FRL
revealed that almost all excitatory postsynaptic sites have AMPARs in the CeC.
The density of AMPAR-specific gold particles in individual synapses was significantly
higher in spine synapses (median 510 particles/μm 2) than in shaft synapses (median
427 particles/μm 2; P = 0.01). These results suggest that distinct synaptic impacts
from PB- and BLA-CeC pathways contribute to the integration of nociceptive and
polymodal information in the CeC.
author:
- first_name: Yu
full_name: Dong, Yu-Lin
last_name: Dong
- first_name: Yugo
full_name: Fukazawa, Yugo
last_name: Fukazawa
- first_name: Wen
full_name: Wang, Wen
last_name: Wang
- first_name: Naomi
full_name: Kamasawa, Naomi
last_name: Kamasawa
- first_name: Ryuichi
full_name: Ryuichi Shigemoto
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
citation:
ama: Dong Y, Fukazawa Y, Wang W, Kamasawa N, Shigemoto R. Differential postsynaptic
compartments in the laterocapsular division of the central nucleus of amygdala
for afferents from the parabrachial nucleus and the basolateral nucleus in the
rat. Journal of Comparative Neurology. 2010;518(23):4771-4791. doi:10.1002/cne.22487
apa: Dong, Y., Fukazawa, Y., Wang, W., Kamasawa, N., & Shigemoto, R. (2010).
Differential postsynaptic compartments in the laterocapsular division of the central
nucleus of amygdala for afferents from the parabrachial nucleus and the basolateral
nucleus in the rat. Journal of Comparative Neurology. Wiley-Blackwell.
https://doi.org/10.1002/cne.22487
chicago: Dong, Yu, Yugo Fukazawa, Wen Wang, Naomi Kamasawa, and Ryuichi Shigemoto.
“Differential Postsynaptic Compartments in the Laterocapsular Division of the
Central Nucleus of Amygdala for Afferents from the Parabrachial Nucleus and the
Basolateral Nucleus in the Rat.” Journal of Comparative Neurology. Wiley-Blackwell,
2010. https://doi.org/10.1002/cne.22487.
ieee: Y. Dong, Y. Fukazawa, W. Wang, N. Kamasawa, and R. Shigemoto, “Differential
postsynaptic compartments in the laterocapsular division of the central nucleus
of amygdala for afferents from the parabrachial nucleus and the basolateral nucleus
in the rat,” Journal of Comparative Neurology, vol. 518, no. 23. Wiley-Blackwell,
pp. 4771–4791, 2010.
ista: Dong Y, Fukazawa Y, Wang W, Kamasawa N, Shigemoto R. 2010. Differential postsynaptic
compartments in the laterocapsular division of the central nucleus of amygdala
for afferents from the parabrachial nucleus and the basolateral nucleus in the
rat. Journal of Comparative Neurology. 518(23), 4771–4791.
mla: Dong, Yu, et al. “Differential Postsynaptic Compartments in the Laterocapsular
Division of the Central Nucleus of Amygdala for Afferents from the Parabrachial
Nucleus and the Basolateral Nucleus in the Rat.” Journal of Comparative Neurology,
vol. 518, no. 23, Wiley-Blackwell, 2010, pp. 4771–91, doi:10.1002/cne.22487.
short: Y. Dong, Y. Fukazawa, W. Wang, N. Kamasawa, R. Shigemoto, Journal of Comparative
Neurology 518 (2010) 4771–4791.
date_created: 2018-12-11T11:58:05Z
date_published: 2010-12-01T00:00:00Z
date_updated: 2021-01-12T06:57:55Z
day: '01'
doi: 10.1002/cne.22487
extern: 1
intvolume: ' 518'
issue: '23'
month: '12'
page: 4771 - 4791
publication: Journal of Comparative Neurology
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4391'
quality_controlled: 0
status: public
title: Differential postsynaptic compartments in the laterocapsular division of the
central nucleus of amygdala for afferents from the parabrachial nucleus and the
basolateral nucleus in the rat
type: journal_article
volume: 518
year: '2010'
...
---
_id: '2701'
abstract:
- lang: eng
text: We consider N × N Hermitian random matrices with independent identically distributed
entries (Wigner matrices). The matrices are normalized so that the average spacing
between consecutive eigenvalues is of order 1/ N. Under suitable assumptions on
the distribution of the single matrix element, we first prove that, away from
the spectral edges, the empirical density of eigenvalues concentrates around the
Wigner semicircle law on energy scales η ≫ N -1. This result establishes the semicircle
law on the optimal scale and it removes a logarithmic factor from our previous
result [6]. We then show a Wegner estimate, i.e., that the averaged density of
states is bounded. Finally, we prove that the eigenvalues of a Wigner matrix repel
each other, in agreement with the universality conjecture.
author:
- first_name: László
full_name: László Erdös
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: Benjamin
full_name: Schlein, Benjamin
last_name: Schlein
- first_name: Horng
full_name: Yau, Horng-Tzer
last_name: Yau
citation:
ama: Erdös L, Schlein B, Yau H. Wegner estimate and level repulsion for Wigner random
matrices. International Mathematics Research Notices. 2010;(3):436-479.
doi:10.1093/imrn/rnp136
apa: Erdös, L., Schlein, B., & Yau, H. (2010). Wegner estimate and level repulsion
for Wigner random matrices. International Mathematics Research Notices.
Oxford University Press. https://doi.org/10.1093/imrn/rnp136
chicago: Erdös, László, Benjamin Schlein, and Horng Yau. “Wegner Estimate and Level
Repulsion for Wigner Random Matrices.” International Mathematics Research Notices.
Oxford University Press, 2010. https://doi.org/10.1093/imrn/rnp136.
ieee: L. Erdös, B. Schlein, and H. Yau, “Wegner estimate and level repulsion for
Wigner random matrices,” International Mathematics Research Notices, no.
3. Oxford University Press, pp. 436–479, 2010.
ista: Erdös L, Schlein B, Yau H. 2010. Wegner estimate and level repulsion for Wigner
random matrices. International Mathematics Research Notices. (3), 436–479.
mla: Erdös, László, et al. “Wegner Estimate and Level Repulsion for Wigner Random
Matrices.” International Mathematics Research Notices, no. 3, Oxford University
Press, 2010, pp. 436–79, doi:10.1093/imrn/rnp136.
short: L. Erdös, B. Schlein, H. Yau, International Mathematics Research Notices
(2010) 436–479.
date_created: 2018-12-11T11:59:09Z
date_published: 2010-01-01T00:00:00Z
date_updated: 2021-01-12T06:59:09Z
day: '01'
doi: 10.1093/imrn/rnp136
extern: 1
issue: '3'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/0811.2591
month: '01'
oa: 1
page: 436 - 479
publication: International Mathematics Research Notices
publication_status: published
publisher: Oxford University Press
publist_id: '4195'
quality_controlled: 0
status: public
title: Wegner estimate and level repulsion for Wigner random matrices
type: journal_article
year: '2010'
...
---
_id: '2704'
abstract:
- lang: eng
text: Consider a system of N bosons in three dimensions interacting via a repulsive
short range pair potential N2V(N(xi-xj)), where x = (x1, ..., xN) denotes the
positions of the particles. Let HN, denote the Hamiltonian of the system and let
ψN,t be the solution to the Schrödinger equation. Suppose that the initial data
ψN,0 satisfies the energy condition 〈 ψ N,0,Hk N ψN,0〉 ≤ CkNk for k =1, 2, ....We
also assume that the k-particle density matrices of the initial state are asymptotically
factorized as N →∞1. We prove that the k-particle density matrices of ψN,t are
also asymptotically factorized and the one particle orbital wave function solves
the Gross-Pitaevskii equation, a cubic nonlinear Schrödinger equation with the
coupling constant given by the scattering length of the potential V. We also prove
the same conclusion if the energy condition holds only for k=1 but the factorization
of ψN,0 is assumed in a stronger sense.
author:
- first_name: László
full_name: László Erdös
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: Benjamin
full_name: Schlein, Benjamin
last_name: Schlein
- first_name: Horng
full_name: Yau, Horng-Tzer
last_name: Yau
citation:
ama: Erdös L, Schlein B, Yau H. Derivation of the Gross-Pitaevskii equation for
the dynamics of Bose-Einstein condensate. Annals of Mathematics. 2010;172(1):291-370.
doi:10.4007/annals.2010.172.291
apa: Erdös, L., Schlein, B., & Yau, H. (2010). Derivation of the Gross-Pitaevskii
equation for the dynamics of Bose-Einstein condensate. Annals of Mathematics.
Princeton University Press. https://doi.org/10.4007/annals.2010.172.291
chicago: Erdös, László, Benjamin Schlein, and Horng Yau. “Derivation of the Gross-Pitaevskii
Equation for the Dynamics of Bose-Einstein Condensate.” Annals of Mathematics.
Princeton University Press, 2010. https://doi.org/10.4007/annals.2010.172.291.
ieee: L. Erdös, B. Schlein, and H. Yau, “Derivation of the Gross-Pitaevskii equation
for the dynamics of Bose-Einstein condensate,” Annals of Mathematics, vol.
172, no. 1. Princeton University Press, pp. 291–370, 2010.
ista: Erdös L, Schlein B, Yau H. 2010. Derivation of the Gross-Pitaevskii equation
for the dynamics of Bose-Einstein condensate. Annals of Mathematics. 172(1), 291–370.
mla: Erdös, László, et al. “Derivation of the Gross-Pitaevskii Equation for the
Dynamics of Bose-Einstein Condensate.” Annals of Mathematics, vol. 172,
no. 1, Princeton University Press, 2010, pp. 291–370, doi:10.4007/annals.2010.172.291.
short: L. Erdös, B. Schlein, H. Yau, Annals of Mathematics 172 (2010) 291–370.
date_created: 2018-12-11T11:59:10Z
date_published: 2010-07-01T00:00:00Z
date_updated: 2021-01-12T06:59:10Z
day: '01'
doi: 10.4007/annals.2010.172.291
extern: 1
intvolume: ' 172'
issue: '1'
main_file_link:
- open_access: '0'
url: http://xxx.lanl.gov/abs/math-ph/0606017
month: '07'
page: 291 - 370
publication: Annals of Mathematics
publication_status: published
publisher: Princeton University Press
publist_id: '4192'
quality_controlled: 0
status: public
title: Derivation of the Gross-Pitaevskii equation for the dynamics of Bose-Einstein
condensate
type: journal_article
volume: 172
year: '2010'
...
---
_id: '2756'
abstract:
- lang: eng
text: We consider a large atom with nuclear charge Z described by non-relativistic
quantum mechanics with classical or quantized electromagnetic field. We prove
that the absolute ground state energy, allowing for minimizing over all possible
self-generated electromagnetic fields, is given by the non-magnetic Thomas-Fermi
theory to leading order in the simultaneous Z → ∞, α → 0 limit if Zα2 ≤ κ for
some universal κ, where α is the fine structure constant.
author:
- first_name: László
full_name: László Erdös
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: Jan
full_name: Solovej, Jan P
last_name: Solovej
citation:
ama: Erdös L, Solovej J. Ground state energy of large atoms in a self-generated
magnetic field. Communications in Mathematical Physics. 2010;294(1):229-249.
doi:10.1007/s00220-009-0869-2
apa: Erdös, L., & Solovej, J. (2010). Ground state energy of large atoms in
a self-generated magnetic field. Communications in Mathematical Physics.
Springer. https://doi.org/10.1007/s00220-009-0869-2
chicago: Erdös, László, and Jan Solovej. “Ground State Energy of Large Atoms in
a Self-Generated Magnetic Field.” Communications in Mathematical Physics.
Springer, 2010. https://doi.org/10.1007/s00220-009-0869-2.
ieee: L. Erdös and J. Solovej, “Ground state energy of large atoms in a self-generated
magnetic field,” Communications in Mathematical Physics, vol. 294, no.
1. Springer, pp. 229–249, 2010.
ista: Erdös L, Solovej J. 2010. Ground state energy of large atoms in a self-generated
magnetic field. Communications in Mathematical Physics. 294(1), 229–249.
mla: Erdös, László, and Jan Solovej. “Ground State Energy of Large Atoms in a Self-Generated
Magnetic Field.” Communications in Mathematical Physics, vol. 294, no.
1, Springer, 2010, pp. 229–49, doi:10.1007/s00220-009-0869-2.
short: L. Erdös, J. Solovej, Communications in Mathematical Physics 294 (2010) 229–249.
date_created: 2018-12-11T11:59:26Z
date_published: 2010-02-01T00:00:00Z
date_updated: 2021-01-12T06:59:29Z
day: '01'
doi: 10.1007/s00220-009-0869-2
extern: 1
intvolume: ' 294'
issue: '1'
month: '02'
page: 229 - 249
publication: Communications in Mathematical Physics
publication_status: published
publisher: Springer
publist_id: '4136'
quality_controlled: 0
status: public
title: Ground state energy of large atoms in a self-generated magnetic field
type: journal_article
volume: 294
year: '2010'
...
---
_id: '2761'
abstract:
- lang: eng
text: We consider N × N Hermitian random matrices with independent identically distributed
entries (Wigner matrices). We assume that the distribution of the entries have
a Gaussian component with variance N 3/4+β for some positive β > 0. We prove
that the local eigenvalue statistics follows the universal Dyson sine kernel.
author:
- first_name: László
full_name: László Erdös
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: José
full_name: Ramírez, José A
last_name: Ramírez
- first_name: Benjamin
full_name: Schlein, Benjamin
last_name: Schlein
- first_name: Horng
full_name: Yau, Horng-Tzer
last_name: Yau
citation:
ama: Erdös L, Ramírez J, Schlein B, Yau H. Universality of sine-kernel for Wigner
matrices with a small Gaussian perturbation. Electronic Journal of Probability.
2010;15(18):526-603. doi:10.1214/EJP.v15-768
apa: Erdös, L., Ramírez, J., Schlein, B., & Yau, H. (2010). Universality of
sine-kernel for Wigner matrices with a small Gaussian perturbation. Electronic
Journal of Probability. Institute of Mathematical Statistics. https://doi.org/10.1214/EJP.v15-768
chicago: Erdös, László, José Ramírez, Benjamin Schlein, and Horng Yau. “Universality
of Sine-Kernel for Wigner Matrices with a Small Gaussian Perturbation.” Electronic
Journal of Probability. Institute of Mathematical Statistics, 2010. https://doi.org/10.1214/EJP.v15-768.
ieee: L. Erdös, J. Ramírez, B. Schlein, and H. Yau, “Universality of sine-kernel
for Wigner matrices with a small Gaussian perturbation,” Electronic Journal
of Probability, vol. 15, no. 18. Institute of Mathematical Statistics, pp.
526–603, 2010.
ista: Erdös L, Ramírez J, Schlein B, Yau H. 2010. Universality of sine-kernel for
Wigner matrices with a small Gaussian perturbation. Electronic Journal of Probability.
15(18), 526–603.
mla: Erdös, László, et al. “Universality of Sine-Kernel for Wigner Matrices with
a Small Gaussian Perturbation.” Electronic Journal of Probability, vol.
15, no. 18, Institute of Mathematical Statistics, 2010, pp. 526–603, doi:10.1214/EJP.v15-768.
short: L. Erdös, J. Ramírez, B. Schlein, H. Yau, Electronic Journal of Probability
15 (2010) 526–603.
date_created: 2018-12-11T11:59:27Z
date_published: 2010-01-01T00:00:00Z
date_updated: 2021-01-12T06:59:31Z
day: '01'
doi: 10.1214/EJP.v15-768
extern: 1
intvolume: ' 15'
issue: '18'
month: '01'
page: 526 - 603
publication: Electronic Journal of Probability
publication_status: published
publisher: Institute of Mathematical Statistics
publist_id: '4131'
quality_controlled: 0
status: public
title: Universality of sine-kernel for Wigner matrices with a small Gaussian perturbation
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
volume: 15
year: '2010'
...
---
_id: '2762'
abstract:
- lang: eng
text: We consider N ×N Hermitian Wigner random matrices H where the probabilitydensity
for each matrix element is given by the density v(x)=e-U(x). We prove that the
eigenvalue statistics in the bulk are given by the Dyson sine kernel provided
that U ∈ C 6(R{double-struck}) with at most polynomially growing derivatives and
v(x)≤C e-c(x) for x large. The proof is based upon an approximate time reversal
of the Dyson Brownian motion combined with the convergence of the eigenvalue density
to the Wigner semicircle law on short scales.
author:
- first_name: László
full_name: László Erdös
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: José
full_name: Ramírez, José A
last_name: Ramírez
- first_name: Horng
full_name: Yau, Horng-Tzer
last_name: Yau
- first_name: Sandrine
full_name: Péché, Sandrine
last_name: Péché
- first_name: Benjamin
full_name: Schlein, Benjamin
last_name: Schlein
citation:
ama: Erdös L, Ramírez J, Yau H, Péché S, Schlein B. Bulk universality for Wigner
matrices. Communications on Pure and Applied Mathematics. 2010;63(7):895-925.
doi:10.1002/cpa.20317
apa: Erdös, L., Ramírez, J., Yau, H., Péché, S., & Schlein, B. (2010). Bulk
universality for Wigner matrices. Communications on Pure and Applied Mathematics.
Wiley-Blackwell. https://doi.org/10.1002/cpa.20317
chicago: Erdös, László, José Ramírez, Horng Yau, Sandrine Péché, and Benjamin Schlein.
“Bulk Universality for Wigner Matrices.” Communications on Pure and Applied
Mathematics. Wiley-Blackwell, 2010. https://doi.org/10.1002/cpa.20317.
ieee: L. Erdös, J. Ramírez, H. Yau, S. Péché, and B. Schlein, “Bulk universality
for Wigner matrices,” Communications on Pure and Applied Mathematics, vol.
63, no. 7. Wiley-Blackwell, pp. 895–925, 2010.
ista: Erdös L, Ramírez J, Yau H, Péché S, Schlein B. 2010. Bulk universality for
Wigner matrices. Communications on Pure and Applied Mathematics. 63(7), 895–925.
mla: Erdös, László, et al. “Bulk Universality for Wigner Matrices.” Communications
on Pure and Applied Mathematics, vol. 63, no. 7, Wiley-Blackwell, 2010, pp.
895–925, doi:10.1002/cpa.20317.
short: L. Erdös, J. Ramírez, H. Yau, S. Péché, B. Schlein, Communications on Pure
and Applied Mathematics 63 (2010) 895–925.
date_created: 2018-12-11T11:59:28Z
date_published: 2010-07-01T00:00:00Z
date_updated: 2021-01-12T06:59:32Z
day: '01'
doi: 10.1002/cpa.20317
extern: 1
intvolume: ' 63'
issue: '7'
month: '07'
page: 895 - 925
publication: Communications on Pure and Applied Mathematics
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4130'
quality_controlled: 0
status: public
title: Bulk universality for Wigner matrices
type: journal_article
volume: 63
year: '2010'
...
---
_id: '2763'
abstract:
- lang: eng
text: In this paper, we consider the ensemble of n×n Wigner Hermitian matrices H
= (hℓk)1≤ℓ,k≤n that generalize the Gaussian unitary ensemble (GUE). The matrix
elements hℓk = h̄ℓk are given by hℓk = n ?1/2(xℓk + √?1yℓk), where xℓk, yℓk for
1 ≤ ℓ < k ≤ n are i.i.d. random variables with mean zero and variance 1/2,
yℓ ℓ = 0 and xℓ ℓ have mean zero and variance 1. We assume the distribution of
xℓk, yℓk to have subexponential decay. In [3], four of the authors recently established
that the gap distribution and averaged k-point correlation of these matrices were
universal (and in particular, agreed with those for GUE) assuming additional regularity
hypotheses on the xℓk, yℓk. In [7], the other two authors, using a different method,
established the same conclusion assuming instead some moment and support conditions
on the xℓk, yℓk. In this short note we observe that the arguments of [3] and [7]
can be combined to establish universality of the gap distribution and averaged
k-point correlations for all Wigner matrices (with subexponentially decaying entries),
with no extra assumptions.
author:
- first_name: László
full_name: László Erdös
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: José
full_name: Ramírez, José A
last_name: Ramírez
- first_name: Benjamin
full_name: Schlein, Benjamin
last_name: Schlein
- first_name: Terence
full_name: Tao, Terence
last_name: Tao
- first_name: Vu
full_name: Van, Vu
last_name: Van
- first_name: Horng
full_name: Yau, Horng-Tzer
last_name: Yau
citation:
ama: Erdös L, Ramírez J, Schlein B, Tao T, Van V, Yau H. Bulk universality for Wigner
Hermitian matrices with subexponential decay. Mathematical Research Letters.
2010;17(4):667-674.
apa: Erdös, L., Ramírez, J., Schlein, B., Tao, T., Van, V., & Yau, H. (2010).
Bulk universality for Wigner Hermitian matrices with subexponential decay. Mathematical
Research Letters. International Press.
chicago: Erdös, László, José Ramírez, Benjamin Schlein, Terence Tao, Vu Van, and
Horng Yau. “Bulk Universality for Wigner Hermitian Matrices with Subexponential
Decay.” Mathematical Research Letters. International Press, 2010.
ieee: L. Erdös, J. Ramírez, B. Schlein, T. Tao, V. Van, and H. Yau, “Bulk universality
for Wigner Hermitian matrices with subexponential decay,” Mathematical Research
Letters, vol. 17, no. 4. International Press, pp. 667–674, 2010.
ista: Erdös L, Ramírez J, Schlein B, Tao T, Van V, Yau H. 2010. Bulk universality
for Wigner Hermitian matrices with subexponential decay. Mathematical Research
Letters. 17(4), 667–674.
mla: Erdös, László, et al. “Bulk Universality for Wigner Hermitian Matrices with
Subexponential Decay.” Mathematical Research Letters, vol. 17, no. 4, International
Press, 2010, pp. 667–74.
short: L. Erdös, J. Ramírez, B. Schlein, T. Tao, V. Van, H. Yau, Mathematical Research
Letters 17 (2010) 667–674.
date_created: 2018-12-11T11:59:28Z
date_published: 2010-07-01T00:00:00Z
date_updated: 2021-01-12T06:59:32Z
day: '01'
extern: 1
intvolume: ' 17'
issue: '4'
month: '07'
page: 667 - 674
publication: Mathematical Research Letters
publication_status: published
publisher: International Press
publist_id: '4129'
quality_controlled: 0
status: public
title: Bulk universality for Wigner Hermitian matrices with subexponential decay
type: journal_article
volume: 17
year: '2010'
...
---
_id: '2798'
abstract:
- lang: eng
text: Flows through pipes and channels are the most common means to transport fluids
in practical applications and equally occur in numerous natural systems. In general,
the transfer of fluids is energetically far more efficient if the motion is smooth
and laminar because the friction losses are lower. However, even at moderate velocities
pipe and channel flows are sensitive to minute disturbances, and in practice most
flows are turbulent. Investigating the motion and spatial distribution of vortices,
we uncovered an amplification mechanism that constantly feeds energy from the
mean shear into turbulent eddies. At intermediate flow rates, a simple control
mechanism suffices to intercept this energy transfer by reducing inflection points
in the velocity profile. When activated, an immediate collapse of turbulence is
observed, and the flow relaminarizes.
author:
- first_name: Björn
full_name: Björn Hof
id: 3A374330-F248-11E8-B48F-1D18A9856A87
last_name: Hof
orcid: 0000-0003-2057-2754
- first_name: Alberto
full_name: de Lózar, Alberto
last_name: De Lózar
- first_name: Marc
full_name: Avila, Marc
last_name: Avila
- first_name: Xiaoyun
full_name: Xiaoyun Tu
id: 2AFD1610-F248-11E8-B48F-1D18A9856A87
last_name: Tu
- first_name: Tobias
full_name: Schneider, Tobias M
last_name: Schneider
citation:
ama: Hof B, De Lózar A, Avila M, Tu X, Schneider T. Eliminating turbulence in spatially
intermittent flows. Science. 2010;327(5972):1491-1494. doi:10.1126/science.1186091
apa: Hof, B., De Lózar, A., Avila, M., Tu, X., & Schneider, T. (2010). Eliminating
turbulence in spatially intermittent flows. Science. American Association
for the Advancement of Science. https://doi.org/10.1126/science.1186091
chicago: Hof, Björn, Alberto De Lózar, Marc Avila, Xiaoyun Tu, and Tobias Schneider.
“Eliminating Turbulence in Spatially Intermittent Flows.” Science. American
Association for the Advancement of Science, 2010. https://doi.org/10.1126/science.1186091.
ieee: B. Hof, A. De Lózar, M. Avila, X. Tu, and T. Schneider, “Eliminating turbulence
in spatially intermittent flows,” Science, vol. 327, no. 5972. American
Association for the Advancement of Science, pp. 1491–1494, 2010.
ista: Hof B, De Lózar A, Avila M, Tu X, Schneider T. 2010. Eliminating turbulence
in spatially intermittent flows. Science. 327(5972), 1491–1494.
mla: Hof, Björn, et al. “Eliminating Turbulence in Spatially Intermittent Flows.”
Science, vol. 327, no. 5972, American Association for the Advancement of
Science, 2010, pp. 1491–94, doi:10.1126/science.1186091.
short: B. Hof, A. De Lózar, M. Avila, X. Tu, T. Schneider, Science 327 (2010) 1491–1494.
date_created: 2018-12-11T11:59:39Z
date_published: 2010-03-19T00:00:00Z
date_updated: 2021-01-12T06:59:47Z
day: '19'
doi: 10.1126/science.1186091
extern: 1
intvolume: ' 327'
issue: '5972'
month: '03'
page: 1491 - 1494
publication: Science
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '4091'
quality_controlled: 0
status: public
title: Eliminating turbulence in spatially intermittent flows
type: journal_article
volume: 327
year: '2010'
...
---
_id: '2870'
abstract:
- lang: eng
text: Dark-grown dicotyledonous seedlings form a hook-like structure at the top
of the hypocotyl, which is controlled by the hormones auxin and ethylene. Hook
formation is dependent on an auxin signal gradient, whereas hook exaggeration
is part of the triple response provoked by ethylene in dark-grown Arabidopsis
seedlings. Several other hormones and light are also known to be involved in hook
development, but the molecular mechanisms that lead to the initial installation
of an auxin gradient are still poorly understood. In this study, we aimed to unravel
the cross-talk between auxin and ethylene in the apical hook. Auxin measurements,
the expression pattern of the auxin reporter DR5::GUS and the localization of
auxin biosynthesis enzymes and influx carriers collectively indicate the necessity
for auxin biosynthesis and efficient auxin translocation from the cotyledons and
meristem into the hypocotyl in order to support proper hook development. Auxin
accumulation in the meristem and cotyledons and in the hypocotyl is increased
∼2-fold upon treatment with ethylene. In addition, a strong ethylene signal leads
to enhanced auxin biosynthesis at the inner side of the hook. Finally, mutant
analysis demonstrates that the auxin influx carrier LAX3 is indispensable for
proper hook formation, whereas the auxin influx carrier AUX1 is involved in the
hook exaggeration phenotype induced by ethylene.
author:
- first_name: Filip
full_name: Vandenbussche, Filip
last_name: Vandenbussche
- first_name: Jan
full_name: Petrášek, Jan
last_name: Petrášek
- first_name: Petra
full_name: Žádníková, Petra
last_name: Žádníková
- first_name: Klára
full_name: Hoyerová, Klára
last_name: Hoyerová
- first_name: Bedřich
full_name: Pešek, Bedřich
last_name: Pešek
- first_name: Vered
full_name: Raz, Vered
last_name: Raz
- first_name: Ranjan
full_name: Swarup, Ranjan
last_name: Swarup
- first_name: Malcolm
full_name: Bennett, Malcolm
last_name: Bennett
- first_name: Eva
full_name: Zažímalová, Eva
last_name: Zažímalová
- first_name: Eva
full_name: Eva Benková
id: 38F4F166-F248-11E8-B48F-1D18A9856A87
last_name: Benková
orcid: 0000-0002-8510-9739
- first_name: Dominique
full_name: Van Der Straeten, Dominique
last_name: Van Der Straeten
citation:
ama: Vandenbussche F, Petrášek J, Žádníková P, et al. The auxin influx carriers
AUX1 and LAX3 are involved in auxin-ethylene interactions during apical hook development
in Arabidopsis thaliana seedlings. Development. 2010;137(4):597-606. doi:10.1242/dev.040790
apa: Vandenbussche, F., Petrášek, J., Žádníková, P., Hoyerová, K., Pešek, B., Raz,
V., … Van Der Straeten, D. (2010). The auxin influx carriers AUX1 and LAX3 are
involved in auxin-ethylene interactions during apical hook development in Arabidopsis
thaliana seedlings. Development. Company of Biologists. https://doi.org/10.1242/dev.040790
chicago: Vandenbussche, Filip, Jan Petrášek, Petra Žádníková, Klára Hoyerová, Bedřich
Pešek, Vered Raz, Ranjan Swarup, et al. “The Auxin Influx Carriers AUX1 and LAX3
Are Involved in Auxin-Ethylene Interactions during Apical Hook Development in
Arabidopsis Thaliana Seedlings.” Development. Company of Biologists, 2010.
https://doi.org/10.1242/dev.040790.
ieee: F. Vandenbussche et al., “The auxin influx carriers AUX1 and LAX3 are
involved in auxin-ethylene interactions during apical hook development in Arabidopsis
thaliana seedlings,” Development, vol. 137, no. 4. Company of Biologists,
pp. 597–606, 2010.
ista: Vandenbussche F, Petrášek J, Žádníková P, Hoyerová K, Pešek B, Raz V, Swarup
R, Bennett M, Zažímalová E, Benková E, Van Der Straeten D. 2010. The auxin influx
carriers AUX1 and LAX3 are involved in auxin-ethylene interactions during apical
hook development in Arabidopsis thaliana seedlings. Development. 137(4), 597–606.
mla: Vandenbussche, Filip, et al. “The Auxin Influx Carriers AUX1 and LAX3 Are Involved
in Auxin-Ethylene Interactions during Apical Hook Development in Arabidopsis Thaliana
Seedlings.” Development, vol. 137, no. 4, Company of Biologists, 2010,
pp. 597–606, doi:10.1242/dev.040790.
short: F. Vandenbussche, J. Petrášek, P. Žádníková, K. Hoyerová, B. Pešek, V. Raz,
R. Swarup, M. Bennett, E. Zažímalová, E. Benková, D. Van Der Straeten, Development
137 (2010) 597–606.
date_created: 2018-12-11T12:00:02Z
date_published: 2010-02-15T00:00:00Z
date_updated: 2021-01-12T07:00:23Z
day: '15'
doi: 10.1242/dev.040790
extern: 1
intvolume: ' 137'
issue: '4'
month: '02'
page: 597 - 606
publication: Development
publication_status: published
publisher: Company of Biologists
publist_id: '3898'
quality_controlled: 0
status: public
title: The auxin influx carriers AUX1 and LAX3 are involved in auxin-ethylene interactions
during apical hook development in Arabidopsis thaliana seedlings
type: journal_article
volume: 137
year: '2010'
...
---
_id: '2872'
abstract:
- lang: eng
text: Unlike locomotive organisms capable of actively approaching essential resources,
sessile plants must efficiently exploit their habitat for water and nutrients.
This involves root-mediated underground interactions allowing plants to adapt
to soils of diverse qualities. The root system of plants is a dynamic structure
that modulates primary root growth and root branching by continuous integration
of environmental inputs, such as nutrition availability, soil aeration, humidity,
or salinity. Root branching is an extremely flexible means to rapidly adjust the
overall surface of the root system and plants have evolved efficient control mechanisms,
including, firstly initiation, when and where to start lateral root formation;
secondly lateral root primordia organogenesis, during which the development of
primordia can be arrested for a certain time; and thirdly lateral root emergence.
Our review will focus on the most recent advances in understanding the molecular
mechanisms involved in the regulation of lateral root initiation and organogenesis
with the main focus on root system of the model plant Arabidopsis thaliana.
author:
- first_name: Eva
full_name: Eva Benková
id: 38F4F166-F248-11E8-B48F-1D18A9856A87
last_name: Benková
orcid: 0000-0002-8510-9739
- first_name: Agnieszka
full_name: Bielach, Agnieszka
last_name: Bielach
citation:
ama: Benková E, Bielach A. Lateral root organogenesis - from cell to organ. Current
Opinion in Plant Biology. 2010;13(6):677-683. doi:10.1016/j.pbi.2010.09.006
apa: Benková, E., & Bielach, A. (2010). Lateral root organogenesis - from cell
to organ. Current Opinion in Plant Biology. Elsevier. https://doi.org/10.1016/j.pbi.2010.09.006
chicago: Benková, Eva, and Agnieszka Bielach. “Lateral Root Organogenesis - from
Cell to Organ.” Current Opinion in Plant Biology. Elsevier, 2010. https://doi.org/10.1016/j.pbi.2010.09.006.
ieee: E. Benková and A. Bielach, “Lateral root organogenesis - from cell to organ,”
Current Opinion in Plant Biology, vol. 13, no. 6. Elsevier, pp. 677–683,
2010.
ista: Benková E, Bielach A. 2010. Lateral root organogenesis - from cell to organ.
Current Opinion in Plant Biology. 13(6), 677–683.
mla: Benková, Eva, and Agnieszka Bielach. “Lateral Root Organogenesis - from Cell
to Organ.” Current Opinion in Plant Biology, vol. 13, no. 6, Elsevier,
2010, pp. 677–83, doi:10.1016/j.pbi.2010.09.006.
short: E. Benková, A. Bielach, Current Opinion in Plant Biology 13 (2010) 677–683.
date_created: 2018-12-11T12:00:03Z
date_published: 2010-12-01T00:00:00Z
date_updated: 2021-01-12T07:00:24Z
day: '01'
doi: 10.1016/j.pbi.2010.09.006
extern: 1
intvolume: ' 13'
issue: '6'
month: '12'
page: 677 - 683
publication: Current Opinion in Plant Biology
publication_status: published
publisher: Elsevier
publist_id: '3895'
quality_controlled: 0
status: public
title: Lateral root organogenesis - from cell to organ
type: journal_article
volume: 13
year: '2010'
...
---
_id: '2873'
abstract:
- lang: eng
text: Nitrate is both a nitrogen source for higher plants and a signal molecule
regulating their development. In Arabidopsis, the NRT1.1 nitrate transporter is
crucial for nitrate signaling governing root growth, and has been proposed to
act as a nitrate sensor. However, the sensing mechanism is unknown. Herein we
show that NRT1.1 not only transports nitrate but also facilitates uptake of the
phytohormone auxin. Moreover, nitrate inhibits NRT1.1-dependent auxin uptake,
suggesting that transduction of nitrate signal by NRT1.1 is associated with a
modification of auxin transport. Among other effects, auxin stimulates lateral
root development. Mutation of NRT1.1 enhances both auxin accumulation in lateral
roots and growth of these roots at low, but not high, nitrate concentration. Thus,
we propose that NRT1.1 represses lateral root growth at low nitrate availability
by promoting basipetal auxin transport out of these roots. This defines a mechanism
connecting nutrient and hormone signaling during organ development.
author:
- first_name: Gabriel
full_name: Krouk, Gabriel
last_name: Krouk
- first_name: Benoît
full_name: Lacombe, Benoît
last_name: Lacombe
- first_name: Agnieszka
full_name: Bielach, Agnieszka
last_name: Bielach
- first_name: Francine
full_name: Perrine-Walker, Francine
last_name: Perrine Walker
- first_name: Kateřina
full_name: Malínská, Kateřina
last_name: Malínská
- first_name: Emmanuelle
full_name: Mounier, Emmanuelle
last_name: Mounier
- first_name: Klára
full_name: Hoyerová, Klára
last_name: Hoyerová
- first_name: Pascal
full_name: Tillard, Pascal
last_name: Tillard
- first_name: Sarah
full_name: Leon, Sarah
last_name: Leon
- first_name: Karin
full_name: Ljung, Karin
last_name: Ljung
- first_name: Eva
full_name: Zažímalová, Eva
last_name: Zažímalová
- first_name: Eva
full_name: Eva Benková
id: 38F4F166-F248-11E8-B48F-1D18A9856A87
last_name: Benková
orcid: 0000-0002-8510-9739
- first_name: Philippe
full_name: Nacry, Philippe
last_name: Nacry
- first_name: Alain
full_name: Gojon, Alain
last_name: Gojon
citation:
ama: Krouk G, Lacombe B, Bielach A, et al. Nitrate-regulated auxin transport by
NRT1.1 defines a mechanism for nutrient sensing in plants. Developmental Cell.
2010;18(6):927-937. doi:10.1016/j.devcel.2010.05.008
apa: Krouk, G., Lacombe, B., Bielach, A., Perrine Walker, F., Malínská, K., Mounier,
E., … Gojon, A. (2010). Nitrate-regulated auxin transport by NRT1.1 defines a
mechanism for nutrient sensing in plants. Developmental Cell. Cell Press.
https://doi.org/10.1016/j.devcel.2010.05.008
chicago: Krouk, Gabriel, Benoît Lacombe, Agnieszka Bielach, Francine Perrine Walker,
Kateřina Malínská, Emmanuelle Mounier, Klára Hoyerová, et al. “Nitrate-Regulated
Auxin Transport by NRT1.1 Defines a Mechanism for Nutrient Sensing in Plants.”
Developmental Cell. Cell Press, 2010. https://doi.org/10.1016/j.devcel.2010.05.008.
ieee: G. Krouk et al., “Nitrate-regulated auxin transport by NRT1.1 defines
a mechanism for nutrient sensing in plants,” Developmental Cell, vol. 18,
no. 6. Cell Press, pp. 927–937, 2010.
ista: Krouk G, Lacombe B, Bielach A, Perrine Walker F, Malínská K, Mounier E, Hoyerová
K, Tillard P, Leon S, Ljung K, Zažímalová E, Benková E, Nacry P, Gojon A. 2010.
Nitrate-regulated auxin transport by NRT1.1 defines a mechanism for nutrient sensing
in plants. Developmental Cell. 18(6), 927–937.
mla: Krouk, Gabriel, et al. “Nitrate-Regulated Auxin Transport by NRT1.1 Defines
a Mechanism for Nutrient Sensing in Plants.” Developmental Cell, vol. 18,
no. 6, Cell Press, 2010, pp. 927–37, doi:10.1016/j.devcel.2010.05.008.
short: G. Krouk, B. Lacombe, A. Bielach, F. Perrine Walker, K. Malínská, E. Mounier,
K. Hoyerová, P. Tillard, S. Leon, K. Ljung, E. Zažímalová, E. Benková, P. Nacry,
A. Gojon, Developmental Cell 18 (2010) 927–937.
date_created: 2018-12-11T12:00:04Z
date_published: 2010-06-15T00:00:00Z
date_updated: 2021-01-12T07:00:24Z
day: '15'
doi: 10.1016/j.devcel.2010.05.008
extern: 1
intvolume: ' 18'
issue: '6'
month: '06'
page: 927 - 937
publication: Developmental Cell
publication_status: published
publisher: Cell Press
publist_id: '3896'
quality_controlled: 0
status: public
title: Nitrate-regulated auxin transport by NRT1.1 defines a mechanism for nutrient
sensing in plants
type: journal_article
volume: 18
year: '2010'
...
---
_id: '2899'
abstract:
- lang: eng
text: Toxin–antitoxin (TA) systems are commonly found on bacterial plasmids. The
antitoxin inhibits toxin activity unless the system is lost from the cell. Then
the shorter lived antitoxin degrades and the cell becomes susceptible to the toxin.
Selection for plasmid-encoded TA systems was initially thought to result from
their reducing the number of plasmid-free cells arising during growth in monoculture.
However, modelling and experiments have shown that this mechanism can only explain
the success of plasmid TA systems under a restricted set of conditions. Previously,
we have proposed and tested an alternative model explaining the success of plasmid
TA systems as a consequence of competition occurring between plasmids during co-infection
of bacterial hosts. Here, we test a further prediction of this model, that competition
between plasmids will lead to the biased accumulation of TA systems on plasmids
relative to chromosomes. Transposon-encoded TA systems were added to populations
of plasmid-containing cells, such that TA systems could insert into either plasmids
or chromosomes. These populations were enriched for transposon-containing cells
and then incubated in environments that did, or did not, allow effective within-host
plasmid competition to occur. Changes in the ratio of plasmid- to chromosome-encoded
TA systems were monitored. In agreement with our model, we found that plasmid-encoded
TA systems had a competitive advantage, but only when host cells were sensitive
to the effect of TA systems. This result demonstrates that within-host competition
between plasmids can select for TA systems.
author:
- first_name: Tim
full_name: Cooper, Tim F
last_name: Cooper
- first_name: Tiago
full_name: Tiago Paixao
id: 2C5658E6-F248-11E8-B48F-1D18A9856A87
last_name: Paixao
orcid: 0000-0003-2361-3953
- first_name: Jack
full_name: Heinemann, Jack A
last_name: Heinemann
citation:
ama: Cooper T, Paixao T, Heinemann J. Within host competition selects for plasmid
encoded toxin–antitoxin systems. Proc R Soc B. 2010;277(1697):3149-3155.
doi:10.1098/rspb.2010.0831
apa: Cooper, T., Paixao, T., & Heinemann, J. (2010). Within host competition
selects for plasmid encoded toxin–antitoxin systems. Proc R Soc B. Wiley-Blackwell.
https://doi.org/10.1098/rspb.2010.0831
chicago: Cooper, Tim, Tiago Paixao, and Jack Heinemann. “Within Host Competition
Selects for Plasmid Encoded Toxin–Antitoxin Systems.” Proc R Soc B. Wiley-Blackwell,
2010. https://doi.org/10.1098/rspb.2010.0831.
ieee: T. Cooper, T. Paixao, and J. Heinemann, “Within host competition selects for
plasmid encoded toxin–antitoxin systems,” Proc R Soc B, vol. 277, no. 1697.
Wiley-Blackwell, pp. 3149–3155, 2010.
ista: Cooper T, Paixao T, Heinemann J. 2010. Within host competition selects for
plasmid encoded toxin–antitoxin systems. Proc R Soc B. 277(1697), 3149–3155.
mla: Cooper, Tim, et al. “Within Host Competition Selects for Plasmid Encoded Toxin–Antitoxin
Systems.” Proc R Soc B, vol. 277, no. 1697, Wiley-Blackwell, 2010, pp.
3149–55, doi:10.1098/rspb.2010.0831.
short: T. Cooper, T. Paixao, J. Heinemann, Proc R Soc B 277 (2010) 3149–3155.
date_created: 2018-12-11T12:00:14Z
date_published: 2010-10-10T00:00:00Z
date_updated: 2021-01-12T07:00:33Z
day: '10'
doi: 10.1098/rspb.2010.0831
extern: 1
intvolume: ' 277'
issue: '1697'
month: '10'
page: 3149 - 3155
publication: Proc R Soc B
publication_status: published
publisher: Wiley-Blackwell
publist_id: '3859'
quality_controlled: 0
status: public
title: Within host competition selects for plasmid encoded toxin–antitoxin systems
type: journal_article
volume: 277
year: '2010'
...