---
_id: '9493'
abstract:
- lang: eng
text: In a number of organisms, transgenes containing transcribed inverted repeats
(IRs) that produce hairpin RNA can trigger RNA-mediated silencing, which is associated
with 21-24 nucleotide small interfering RNAs (siRNAs). In plants, IR-driven RNA
silencing also causes extensive cytosine methylation of homologous DNA in both
the transgene "trigger" and any other homologous DNA sequences--"targets". Endogenous
genomic sequences, including transposable elements and repeated elements, are
also subject to RNA-mediated silencing. The RNA silencing gene ARGONAUTE4 (AGO4)
is required for maintenance of DNA methylation at several endogenous loci and
for the establishment of methylation at the FWA gene. Here, we show that mutation
of AGO4 substantially reduces the maintenance of DNA methylation triggered by
IR transgenes, but AGO4 loss-of-function does not block the initiation of DNA
methylation by IRs. AGO4 primarily affects non-CG methylation of the target sequences,
while the IR trigger sequences lose methylation in all sequence contexts. Finally,
we find that AGO4 and the DRM methyltransferase genes are required for maintenance
of siRNAs at a subset of endogenous sequences, but AGO4 is not required for the
accumulation of IR-induced siRNAs or a number of endogenous siRNAs, suggesting
that AGO4 may function downstream of siRNA production.
article_processing_charge: No
article_type: original
author:
- first_name: Daniel
full_name: Zilberman, Daniel
id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
last_name: Zilberman
orcid: 0000-0002-0123-8649
- first_name: Xiaofeng
full_name: Cao, Xiaofeng
last_name: Cao
- first_name: Lisa K.
full_name: Johansen, Lisa K.
last_name: Johansen
- first_name: Zhixin
full_name: Xie, Zhixin
last_name: Xie
- first_name: James C.
full_name: Carrington, James C.
last_name: Carrington
- first_name: Steven E.
full_name: Jacobsen, Steven E.
last_name: Jacobsen
citation:
ama: Zilberman D, Cao X, Johansen LK, Xie Z, Carrington JC, Jacobsen SE. Role of
Arabidopsis ARGONAUTE4 in RNA-directed DNA methylation triggered by inverted repeats.
Current Biology. 2004;14(13):1214-1220. doi:10.1016/j.cub.2004.06.055
apa: Zilberman, D., Cao, X., Johansen, L. K., Xie, Z., Carrington, J. C., &
Jacobsen, S. E. (2004). Role of Arabidopsis ARGONAUTE4 in RNA-directed DNA methylation
triggered by inverted repeats. Current Biology. Elsevier. https://doi.org/10.1016/j.cub.2004.06.055
chicago: Zilberman, Daniel, Xiaofeng Cao, Lisa K. Johansen, Zhixin Xie, James C.
Carrington, and Steven E. Jacobsen. “Role of Arabidopsis ARGONAUTE4 in RNA-Directed
DNA Methylation Triggered by Inverted Repeats.” Current Biology. Elsevier,
2004. https://doi.org/10.1016/j.cub.2004.06.055.
ieee: D. Zilberman, X. Cao, L. K. Johansen, Z. Xie, J. C. Carrington, and S. E.
Jacobsen, “Role of Arabidopsis ARGONAUTE4 in RNA-directed DNA methylation triggered
by inverted repeats,” Current Biology, vol. 14, no. 13. Elsevier, pp. 1214–1220,
2004.
ista: Zilberman D, Cao X, Johansen LK, Xie Z, Carrington JC, Jacobsen SE. 2004.
Role of Arabidopsis ARGONAUTE4 in RNA-directed DNA methylation triggered by inverted
repeats. Current Biology. 14(13), 1214–1220.
mla: Zilberman, Daniel, et al. “Role of Arabidopsis ARGONAUTE4 in RNA-Directed DNA
Methylation Triggered by Inverted Repeats.” Current Biology, vol. 14, no.
13, Elsevier, 2004, pp. 1214–20, doi:10.1016/j.cub.2004.06.055.
short: D. Zilberman, X. Cao, L.K. Johansen, Z. Xie, J.C. Carrington, S.E. Jacobsen,
Current Biology 14 (2004) 1214–1220.
date_created: 2021-06-07T10:33:00Z
date_published: 2004-07-13T00:00:00Z
date_updated: 2021-12-14T08:52:00Z
day: '13'
department:
- _id: DaZi
doi: 10.1016/j.cub.2004.06.055
extern: '1'
external_id:
pmid:
- '15242620 '
intvolume: ' 14'
issue: '13'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.cub.2004.06.055
month: '07'
oa: 1
oa_version: Published Version
page: 1214-1220
pmid: 1
publication: Current Biology
publication_identifier:
eissn:
- 1879-0445
issn:
- 0960-9822
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Role of Arabidopsis ARGONAUTE4 in RNA-directed DNA methylation triggered by
inverted repeats
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 14
year: '2004'
...
---
_id: '9511'
abstract:
- lang: eng
text: Recent progress in understanding the silencing of transposable elements in
the model plant Arabidopsis has revealed an interplay between DNA methylation,
histone methylation and small interfering RNAs. DNA and histone methylation are
not always sufficient to maintain silencing, and RNA-based reinforcement can be
needed to maintain as well as initiate it.
article_number: '249'
article_processing_charge: No
article_type: review
author:
- first_name: Daniel
full_name: Zilberman, Daniel
id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
last_name: Zilberman
orcid: 0000-0002-0123-8649
- first_name: Steven
full_name: Henikoff, Steven
last_name: Henikoff
citation:
ama: 'Zilberman D, Henikoff S. Silencing of transposons in plant genomes: kick them
when they’re down. Genome Biology. 2004;5(12). doi:10.1186/gb-2004-5-12-249'
apa: 'Zilberman, D., & Henikoff, S. (2004). Silencing of transposons in plant
genomes: kick them when they’re down. Genome Biology. Springer Nature.
https://doi.org/10.1186/gb-2004-5-12-249'
chicago: 'Zilberman, Daniel, and Steven Henikoff. “Silencing of Transposons in Plant
Genomes: Kick Them When They’re Down.” Genome Biology. Springer Nature,
2004. https://doi.org/10.1186/gb-2004-5-12-249.'
ieee: 'D. Zilberman and S. Henikoff, “Silencing of transposons in plant genomes:
kick them when they’re down,” Genome Biology, vol. 5, no. 12. Springer
Nature, 2004.'
ista: 'Zilberman D, Henikoff S. 2004. Silencing of transposons in plant genomes:
kick them when they’re down. Genome Biology. 5(12), 249.'
mla: 'Zilberman, Daniel, and Steven Henikoff. “Silencing of Transposons in Plant
Genomes: Kick Them When They’re Down.” Genome Biology, vol. 5, no. 12,
249, Springer Nature, 2004, doi:10.1186/gb-2004-5-12-249.'
short: D. Zilberman, S. Henikoff, Genome Biology 5 (2004).
date_created: 2021-06-07T12:58:06Z
date_published: 2004-11-16T00:00:00Z
date_updated: 2021-12-14T08:44:24Z
day: '16'
department:
- _id: DaZi
doi: 10.1186/gb-2004-5-12-249
extern: '1'
external_id:
pmid:
- '15575975'
intvolume: ' 5'
issue: '12'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1186/gb-2004-5-12-249
month: '11'
oa: 1
oa_version: Published Version
pmid: 1
publication: Genome Biology
publication_identifier:
eissn:
- 1465-6906
issn:
- 1474-760X
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Silencing of transposons in plant genomes: kick them when they''re down'
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 5
year: '2004'
...
---
_id: '9517'
abstract:
- lang: eng
text: Multicellular eukaryotes produce small RNA molecules (approximately 21–24
nucleotides) of two general types, microRNA (miRNA) and short interfering RNA
(siRNA). They collectively function as sequence-specific guides to silence or
regulate genes, transposons, and viruses and to modify chromatin and genome structure.
Formation or activity of small RNAs requires factors belonging to gene families
that encode DICER (or DICER-LIKE [DCL]) and ARGONAUTE proteins and, in the case
of some siRNAs, RNA-dependent RNA polymerase (RDR) proteins. Unlike many animals,
plants encode multiple DCL and RDR proteins. Using a series of insertion mutants
of Arabidopsis thaliana, unique functions for three DCL proteins in miRNA (DCL1),
endogenous siRNA (DCL3), and viral siRNA (DCL2) biogenesis were identified. One
RDR protein (RDR2) was required for all endogenous siRNAs analyzed. The loss of
endogenous siRNA in dcl3 and rdr2 mutants was associated with loss of heterochromatic
marks and increased transcript accumulation at some loci. Defects in siRNA-generation
activity in response to turnip crinkle virus in dcl2 mutant plants correlated
with increased virus susceptibility. We conclude that proliferation and diversification
of DCL and RDR genes during evolution of plants contributed to specialization
of small RNA-directed pathways for development, chromatin structure, and defense.
article_processing_charge: No
article_type: original
author:
- first_name: Zhixin
full_name: Xie, Zhixin
last_name: Xie
- first_name: Lisa K.
full_name: Johansen, Lisa K.
last_name: Johansen
- first_name: Adam M.
full_name: Gustafson, Adam M.
last_name: Gustafson
- first_name: Kristin D.
full_name: Kasschau, Kristin D.
last_name: Kasschau
- first_name: 'Andrew D. '
full_name: 'Lellis, Andrew D. '
last_name: Lellis
- first_name: Daniel
full_name: Zilberman, Daniel
id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
last_name: Zilberman
orcid: 0000-0002-0123-8649
- first_name: Steven E.
full_name: Jacobsen, Steven E.
last_name: Jacobsen
- first_name: James C.
full_name: Carrington, James C.
last_name: Carrington
citation:
ama: Xie Z, Johansen LK, Gustafson AM, et al. Genetic and functional diversification
of small RNA pathways in plants. PLoS Biology. 2004;2(5):0642-0652. doi:10.1371/journal.pbio.0020104
apa: Xie, Z., Johansen, L. K., Gustafson, A. M., Kasschau, K. D., Lellis, A. D.,
Zilberman, D., … Carrington, J. C. (2004). Genetic and functional diversification
of small RNA pathways in plants. PLoS Biology. Public Library of Science.
https://doi.org/10.1371/journal.pbio.0020104
chicago: Xie, Zhixin, Lisa K. Johansen, Adam M. Gustafson, Kristin D. Kasschau,
Andrew D. Lellis, Daniel Zilberman, Steven E. Jacobsen, and James C. Carrington.
“Genetic and Functional Diversification of Small RNA Pathways in Plants.” PLoS
Biology. Public Library of Science, 2004. https://doi.org/10.1371/journal.pbio.0020104.
ieee: Z. Xie et al., “Genetic and functional diversification of small RNA
pathways in plants,” PLoS Biology, vol. 2, no. 5. Public Library of Science,
pp. 0642–0652, 2004.
ista: Xie Z, Johansen LK, Gustafson AM, Kasschau KD, Lellis AD, Zilberman D, Jacobsen
SE, Carrington JC. 2004. Genetic and functional diversification of small RNA pathways
in plants. PLoS Biology. 2(5), 0642–0652.
mla: Xie, Zhixin, et al. “Genetic and Functional Diversification of Small RNA Pathways
in Plants.” PLoS Biology, vol. 2, no. 5, Public Library of Science, 2004,
pp. 0642–52, doi:10.1371/journal.pbio.0020104.
short: Z. Xie, L.K. Johansen, A.M. Gustafson, K.D. Kasschau, A.D. Lellis, D. Zilberman,
S.E. Jacobsen, J.C. Carrington, PLoS Biology 2 (2004) 0642–0652.
date_created: 2021-06-07T14:12:08Z
date_published: 2004-02-24T00:00:00Z
date_updated: 2021-12-14T08:43:57Z
day: '24'
department:
- _id: DaZi
doi: 10.1371/journal.pbio.0020104
extern: '1'
external_id:
pmid:
- '15024409'
intvolume: ' 2'
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1371/journal.pbio.0020104
month: '02'
oa: 1
oa_version: Published Version
page: 0642-0652
pmid: 1
publication: PLoS Biology
publication_identifier:
eissn:
- 1545-7885
issn:
- 1544-9173
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Genetic and functional diversification of small RNA pathways in plants
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 2
year: '2004'
...
---
_id: '11762'
abstract:
- lang: eng
text: 'In this paper, we describe six algorithmic problems that arise in web search
engines and that are not or only partially solved: (1) Uniformly sampling of web
pages; (2) modeling the web graph; (3) finding duplicate hosts; (4) finding top
gainers and losers in data streams; (5) finding large dense bipartite graphs; and
(6) understanding how eigenvectors partition the web.'
article_processing_charge: No
article_type: original
author:
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
citation:
ama: Henzinger MH. Algorithmic challenges in web search engines. Internet Mathematics.
2004;1(1):115-123. doi:10.1080/15427951.2004.10129079
apa: Henzinger, M. H. (2004). Algorithmic challenges in web search engines. Internet
Mathematics. Internet Mathematics. https://doi.org/10.1080/15427951.2004.10129079
chicago: Henzinger, Monika H. “Algorithmic Challenges in Web Search Engines.” Internet
Mathematics. Internet Mathematics, 2004. https://doi.org/10.1080/15427951.2004.10129079.
ieee: M. H. Henzinger, “Algorithmic challenges in web search engines,” Internet
Mathematics, vol. 1, no. 1. Internet Mathematics, pp. 115–123, 2004.
ista: Henzinger MH. 2004. Algorithmic challenges in web search engines. Internet
Mathematics. 1(1), 115–123.
mla: Henzinger, Monika H. “Algorithmic Challenges in Web Search Engines.” Internet
Mathematics, vol. 1, no. 1, Internet Mathematics, 2004, pp. 115–23, doi:10.1080/15427951.2004.10129079.
short: M.H. Henzinger, Internet Mathematics 1 (2004) 115–123.
date_created: 2022-08-08T11:55:53Z
date_published: 2004-01-01T00:00:00Z
date_updated: 2023-02-10T07:47:21Z
day: '01'
doi: 10.1080/15427951.2004.10129079
extern: '1'
intvolume: ' 1'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1080/15427951.2004.10129079
month: '01'
oa: 1
oa_version: Published Version
page: 115-123
publication: Internet Mathematics
publication_identifier:
eissn:
- 1944-9488
issn:
- 1542-7951
publication_status: published
publisher: Internet Mathematics
quality_controlled: '1'
scopus_import: '1'
status: public
title: Algorithmic challenges in web search engines
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 1
year: '2004'
...
---
_id: '11800'
abstract:
- lang: eng
text: "Web search engines have emerged as one of the central applications on the
Internet. In fact, search has become one of the most important activities that
people engage in on the the Internet. Even beyond becoming the number one source
of information, a growing number of businesses are depending on web search engines
for customer acquisition.\r\n\r\nThe first generation of web search engines used
text-only retrieval techniques. Google revolutionized the field by deploying the
PageRank technology – an eigenvector-based analysis of the hyperlink structure
– to analyze the web in order to produce relevant results. Moving forward, our
goal is to achieve a better understanding of a page with a view towards producing
even more relevant results."
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
citation:
ama: 'Henzinger MH. The past, present, and future of web search engines. In: 31st
International Colloquium on Automata, Languages and Programming. Vol 3142.
Springer Nature; 2004:3. doi:10.1007/978-3-540-27836-8_2'
apa: 'Henzinger, M. H. (2004). The past, present, and future of web search engines.
In 31st International Colloquium on Automata, Languages and Programming
(Vol. 3142, p. 3). Turku, Finland: Springer Nature. https://doi.org/10.1007/978-3-540-27836-8_2'
chicago: Henzinger, Monika H. “The Past, Present, and Future of Web Search Engines.”
In 31st International Colloquium on Automata, Languages and Programming,
3142:3. Springer Nature, 2004. https://doi.org/10.1007/978-3-540-27836-8_2.
ieee: M. H. Henzinger, “The past, present, and future of web search engines,” in
31st International Colloquium on Automata, Languages and Programming, Turku,
Finland, 2004, vol. 3142, p. 3.
ista: 'Henzinger MH. 2004. The past, present, and future of web search engines.
31st International Colloquium on Automata, Languages and Programming. ICALP: International
Colloquium on Automata, Languages, and Programming, LNCS, vol. 3142, 3.'
mla: Henzinger, Monika H. “The Past, Present, and Future of Web Search Engines.”
31st International Colloquium on Automata, Languages and Programming, vol.
3142, Springer Nature, 2004, p. 3, doi:10.1007/978-3-540-27836-8_2.
short: M.H. Henzinger, in:, 31st International Colloquium on Automata, Languages
and Programming, Springer Nature, 2004, p. 3.
conference:
end_date: 2004-07-16
location: Turku, Finland
name: 'ICALP: International Colloquium on Automata, Languages, and Programming'
start_date: 2004-07-12
date_created: 2022-08-11T12:38:58Z
date_published: 2004-07-01T00:00:00Z
date_updated: 2023-02-13T11:45:25Z
day: '01'
doi: 10.1007/978-3-540-27836-8_2
extern: '1'
intvolume: ' 3142'
language:
- iso: eng
month: '07'
oa_version: None
page: '3'
publication: 31st International Colloquium on Automata, Languages and Programming
publication_identifier:
eissn:
- 1611-3349
issn:
- 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: The past, present, and future of web search engines
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 3142
year: '2004'
...
---
_id: '11801'
abstract:
- lang: eng
text: "Web search engines have emerged as one of the central applications on the
internet. In fact, search has become one of the most important activities that
people engage in on the Internet. Even beyond becoming the number one source of
information, a growing number of businesses are depending on web search engines
for customer acquisition. In this talk I will brief review the history of web
search engines: The first generation of web search engines used text-only retrieval
techniques. Google revolutionized the field by deploying the PageRank technology
– an eigenvector-based analysis of the hyperlink structure- to analyze the web
in order to produce relevant results. Moving forward, our goal is to achieve a
better understanding of a page with a view towards producing even more relevant
results.\r\n\r\nGoogle is powered by a large number of PCs. Using this infrastructure
and striving to be as efficient as possible poses challenging systems problems
but also various algorithmic challenges. I will discuss some of them in my talk."
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
citation:
ama: 'Henzinger MH. Algorithmic aspects of web search engines. In: 2th Annual
European Symposium on Algorithms. Vol 3221. Springer Nature; 2004:3. doi:10.1007/978-3-540-30140-0_2'
apa: 'Henzinger, M. H. (2004). Algorithmic aspects of web search engines. In 2th
Annual European Symposium on Algorithms (Vol. 3221, p. 3). Bergen, Norway:
Springer Nature. https://doi.org/10.1007/978-3-540-30140-0_2'
chicago: Henzinger, Monika H. “Algorithmic Aspects of Web Search Engines.” In 2th
Annual European Symposium on Algorithms, 3221:3. Springer Nature, 2004. https://doi.org/10.1007/978-3-540-30140-0_2.
ieee: M. H. Henzinger, “Algorithmic aspects of web search engines,” in 2th Annual
European Symposium on Algorithms, Bergen, Norway, 2004, vol. 3221, p. 3.
ista: 'Henzinger MH. 2004. Algorithmic aspects of web search engines. 2th Annual
European Symposium on Algorithms. ESA: European Symposium on Algorithms, LNCS,
vol. 3221, 3.'
mla: Henzinger, Monika H. “Algorithmic Aspects of Web Search Engines.” 2th Annual
European Symposium on Algorithms, vol. 3221, Springer Nature, 2004, p. 3,
doi:10.1007/978-3-540-30140-0_2.
short: M.H. Henzinger, in:, 2th Annual European Symposium on Algorithms, Springer
Nature, 2004, p. 3.
conference:
end_date: 2004-09-17
location: Bergen, Norway
name: 'ESA: European Symposium on Algorithms'
start_date: 2004-09-14
date_created: 2022-08-11T13:18:05Z
date_published: 2004-09-01T00:00:00Z
date_updated: 2023-02-13T11:47:26Z
day: '01'
doi: 10.1007/978-3-540-30140-0_2
extern: '1'
intvolume: ' 3221'
language:
- iso: eng
month: '09'
oa_version: None
page: '3'
publication: 2th Annual European Symposium on Algorithms
publication_identifier:
eissn:
- 1611-3349
isbn:
- ' 3540230254'
issn:
- 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Algorithmic aspects of web search engines
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 3221
year: '2004'
...
---
_id: '11859'
abstract:
- lang: eng
text: In this article we describe the approach taken by the first web search engines,
discuss the state of the art, and present some of the challenges for the future.
article_processing_charge: No
author:
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
citation:
ama: 'Henzinger MH. The past, present, and future of web information retrieval.
In: SPIE Proceedings. Vol 5296. Society of Photo-Optical Instrumentation
Engineers; 2004:23-26. doi:10.1117/12.537534'
apa: 'Henzinger, M. H. (2004). The past, present, and future of web information
retrieval. In SPIE Proceedings (Vol. 5296, pp. 23–26). San Jose, CA, United
States: Society of Photo-Optical Instrumentation Engineers. https://doi.org/10.1117/12.537534'
chicago: Henzinger, Monika H. “The Past, Present, and Future of Web Information
Retrieval.” In SPIE Proceedings, 5296:23–26. Society of Photo-Optical Instrumentation
Engineers, 2004. https://doi.org/10.1117/12.537534.
ieee: M. H. Henzinger, “The past, present, and future of web information retrieval,”
in SPIE Proceedings, San Jose, CA, United States, 2004, vol. 5296, pp.
23–26.
ista: Henzinger MH. 2004. The past, present, and future of web information retrieval.
SPIE Proceedings. Document Recognition and Retrieval XI vol. 5296, 23–26.
mla: Henzinger, Monika H. “The Past, Present, and Future of Web Information Retrieval.”
SPIE Proceedings, vol. 5296, Society of Photo-Optical Instrumentation Engineers,
2004, pp. 23–26, doi:10.1117/12.537534.
short: M.H. Henzinger, in:, SPIE Proceedings, Society of Photo-Optical Instrumentation
Engineers, 2004, pp. 23–26.
conference:
end_date: 2004-01-22
location: San Jose, CA, United States
name: Document Recognition and Retrieval XI
start_date: 2004-01-21
date_created: 2022-08-16T08:46:41Z
date_published: 2004-01-01T00:00:00Z
date_updated: 2023-02-17T10:05:19Z
day: '01'
doi: 10.1117/12.537534
extern: '1'
intvolume: ' 5296'
language:
- iso: eng
month: '01'
oa_version: None
page: 23 - 26
publication: SPIE Proceedings
publication_identifier:
issn:
- 0277-786X
publication_status: published
publisher: Society of Photo-Optical Instrumentation Engineers
quality_controlled: '1'
scopus_import: '1'
status: public
title: The past, present, and future of web information retrieval
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 5296
year: '2004'
...
---
_id: '11877'
abstract:
- lang: eng
text: The World Wide Web provides a unprecedented opportunity to automatically analyze
a large sample of interests and activity in the world. We discuss methods for
extracting knowledge from the web by randomly sampling and analyzing hosts and
pages, and by analyzing the link structure of the web and how links accumulate
over time. A variety of interesting and valuable information can be extracted,
such as the distribution of web pages over domains, the distribution of interest
in different areas, communities related to different topics, the nature of competition
in different categories of sites, and the degree of communication between different
communities or countries.
article_processing_charge: No
article_type: original
author:
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
- first_name: Steve
full_name: Lawrence, Steve
last_name: Lawrence
citation:
ama: Henzinger MH, Lawrence S. Extracting knowledge from the World Wide Web. Proceedings
of the National Academy of Sciences. 2004;101(suppl_1):5186-5191. doi:10.1073/pnas.0307528100
apa: Henzinger, M. H., & Lawrence, S. (2004). Extracting knowledge from the
World Wide Web. Proceedings of the National Academy of Sciences. Proceedings
of the National Academy of Sciences. https://doi.org/10.1073/pnas.0307528100
chicago: Henzinger, Monika H, and Steve Lawrence. “Extracting Knowledge from the
World Wide Web.” Proceedings of the National Academy of Sciences. Proceedings
of the National Academy of Sciences, 2004. https://doi.org/10.1073/pnas.0307528100.
ieee: M. H. Henzinger and S. Lawrence, “Extracting knowledge from the World Wide
Web,” Proceedings of the National Academy of Sciences, vol. 101, no. suppl_1.
Proceedings of the National Academy of Sciences, pp. 5186–5191, 2004.
ista: Henzinger MH, Lawrence S. 2004. Extracting knowledge from the World Wide Web.
Proceedings of the National Academy of Sciences. 101(suppl_1), 5186–5191.
mla: Henzinger, Monika H., and Steve Lawrence. “Extracting Knowledge from the World
Wide Web.” Proceedings of the National Academy of Sciences, vol. 101, no.
suppl_1, Proceedings of the National Academy of Sciences, 2004, pp. 5186–91, doi:10.1073/pnas.0307528100.
short: M.H. Henzinger, S. Lawrence, Proceedings of the National Academy of Sciences
101 (2004) 5186–5191.
date_created: 2022-08-16T13:06:10Z
date_published: 2004-04-06T00:00:00Z
date_updated: 2023-02-17T12:21:43Z
day: '06'
doi: 10.1073/pnas.0307528100
extern: '1'
external_id:
pmid:
- '14745041'
intvolume: ' 101'
issue: suppl_1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC387294/
month: '04'
oa: 1
oa_version: Published Version
page: 5186-5191
pmid: 1
publication: Proceedings of the National Academy of Sciences
publication_identifier:
eissn:
- 1091-6490
issn:
- 0027-8424
publication_status: published
publisher: Proceedings of the National Academy of Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: Extracting knowledge from the World Wide Web
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 101
year: '2004'
...
---
_id: '209'
author:
- first_name: Timothy D
full_name: Timothy Browning
id: 35827D50-F248-11E8-B48F-1D18A9856A87
last_name: Browning
orcid: 0000-0002-8314-0177
- first_name: Roger
full_name: Heath-Brown, Roger
last_name: Heath Brown
citation:
ama: Browning TD, Heath Brown R. Equal sums of three powers. Inventiones Mathematicae.
2004;157(3):553-573. doi:10.1007/s00222-004-0360-9
apa: Browning, T. D., & Heath Brown, R. (2004). Equal sums of three powers.
Inventiones Mathematicae. Unknown. https://doi.org/10.1007/s00222-004-0360-9
chicago: Browning, Timothy D, and Roger Heath Brown. “Equal Sums of Three Powers.”
Inventiones Mathematicae. Unknown, 2004. https://doi.org/10.1007/s00222-004-0360-9.
ieee: T. D. Browning and R. Heath Brown, “Equal sums of three powers,” Inventiones
Mathematicae, vol. 157, no. 3. Unknown, pp. 553–573, 2004.
ista: Browning TD, Heath Brown R. 2004. Equal sums of three powers. Inventiones
Mathematicae. 157(3), 553–573.
mla: Browning, Timothy D., and Roger Heath Brown. “Equal Sums of Three Powers.”
Inventiones Mathematicae, vol. 157, no. 3, Unknown, 2004, pp. 553–73, doi:10.1007/s00222-004-0360-9.
short: T.D. Browning, R. Heath Brown, Inventiones Mathematicae 157 (2004) 553–573.
date_created: 2018-12-11T11:45:13Z
date_published: 2004-03-17T00:00:00Z
date_updated: 2021-01-12T06:55:14Z
day: '17'
doi: 10.1007/s00222-004-0360-9
extern: 1
intvolume: ' 157'
issue: '3'
month: '03'
page: 553 - 573
publication: Inventiones Mathematicae
publication_status: published
publisher: Unknown
publist_id: '7703'
quality_controlled: 0
status: public
title: Equal sums of three powers
type: journal_article
volume: 157
year: '2004'
...
---
_id: '2308'
abstract:
- lang: eng
text: It is widely believed that the inflammatory events mediated by microglial
activation contribute to several neurodegenerative processes. Alzheimer's disease,
for example, is characterized by an accumulation of β-amyloid protein (Aβ) in
neuritic plaques that are infiltrated by reactive microglia and astrocytes. Although
Aβ and its fragment 25-35 exert a direct toxic effect on neurons, they also activate
microglia. Microglial activation is accompanied by morphological changes, cell
proliferation, and release of various cytokines and growth factors. A number of
scientific reports suggest that the increased proliferation of microglial cells
is dependent on ionic membrane currents and in particular on chloride conductances.
An unusual chloride ion channel known to be associated with macrophage activation
is the chloride intracellular channel-1 (CLIC1). Here we show that Aβ stimulation
of neonatal rat microglia specifically leads to the increase in CLIC1 protein
and to the functional expression of CLIC1 chloride conductance, both barely detectable
on the plasma membrane of quiescent cells. CLIC1 protein expression in microglia
increases after 24 hr of incubation with Aβ, simultaneously with the production
of reactive nitrogen intermediates and of tumor necrosis factor-α (TNF-α). We
demonstrate that reducing CLIC1 chloride conductance by a specific blocker [IAA-94
(R(+)-[(6,7-dichloro-2-cyclopentyl-2,3-dihydro-2-methyl-1-oxo-1H-inden-5yl)-oxy]
acetic acid)] prevents neuronal apoptosis in neurons cocultured with Aβ-treated
microglia. Furthermore, we show that small interfering RNAs used to knock down
CLIC1 expression prevent TNF-α release induced by Aβ stimulation. These results
provide a direct link between Aβ-induced microglial activation and CLIC1 functional
expression.
author:
- first_name: Gaia
full_name: Gaia Novarino
id: 3E57A680-F248-11E8-B48F-1D18A9856A87
last_name: Novarino
orcid: 0000-0002-7673-7178
- first_name: Cinzia
full_name: Fabrizi, Cinzia
last_name: Fabrizi
- first_name: Raffaella
full_name: Tonini, Raffaella
last_name: Tonini
- first_name: Michela
full_name: Denti, Michela A
last_name: Denti
- first_name: Albedi
full_name: Malchiodi, Albedi F
last_name: Malchiodi
- first_name: Giuliana
full_name: Lauro, Giuliana M
last_name: Lauro
- first_name: Benedetto
full_name: Sacchetti, Benedetto
last_name: Sacchetti
- first_name: Silvia
full_name: Paradisi, Silvia
last_name: Paradisi
- first_name: Arnaldo
full_name: Ferroni, Arnaldo
last_name: Ferroni
- first_name: Paul
full_name: Curmi, Paul M G
last_name: Curmi
- first_name: Samuel
full_name: Breit, Samuel N
last_name: Breit
- first_name: Michele
full_name: Mazzanti, Michele
last_name: Mazzanti
citation:
ama: Novarino G, Fabrizi C, Tonini R, et al. Involvement of the intracellular ion
channel CLIC1 in microglia-mediated β-amyloid-induced neurotoxicity. Journal
of Neuroscience. 2004;24(23):5322-5330. doi:10.1523/JNEUROSCI.1170-04.2004
apa: Novarino, G., Fabrizi, C., Tonini, R., Denti, M., Malchiodi, A., Lauro, G.,
… Mazzanti, M. (2004). Involvement of the intracellular ion channel CLIC1 in microglia-mediated
β-amyloid-induced neurotoxicity. Journal of Neuroscience. Society for Neuroscience.
https://doi.org/10.1523/JNEUROSCI.1170-04.2004
chicago: Novarino, Gaia, Cinzia Fabrizi, Raffaella Tonini, Michela Denti, Albedi
Malchiodi, Giuliana Lauro, Benedetto Sacchetti, et al. “Involvement of the Intracellular
Ion Channel CLIC1 in Microglia-Mediated β-Amyloid-Induced Neurotoxicity.” Journal
of Neuroscience. Society for Neuroscience, 2004. https://doi.org/10.1523/JNEUROSCI.1170-04.2004.
ieee: G. Novarino et al., “Involvement of the intracellular ion channel CLIC1
in microglia-mediated β-amyloid-induced neurotoxicity,” Journal of Neuroscience,
vol. 24, no. 23. Society for Neuroscience, pp. 5322–5330, 2004.
ista: Novarino G, Fabrizi C, Tonini R, Denti M, Malchiodi A, Lauro G, Sacchetti
B, Paradisi S, Ferroni A, Curmi P, Breit S, Mazzanti M. 2004. Involvement of the
intracellular ion channel CLIC1 in microglia-mediated β-amyloid-induced neurotoxicity.
Journal of Neuroscience. 24(23), 5322–5330.
mla: Novarino, Gaia, et al. “Involvement of the Intracellular Ion Channel CLIC1
in Microglia-Mediated β-Amyloid-Induced Neurotoxicity.” Journal of Neuroscience,
vol. 24, no. 23, Society for Neuroscience, 2004, pp. 5322–30, doi:10.1523/JNEUROSCI.1170-04.2004.
short: G. Novarino, C. Fabrizi, R. Tonini, M. Denti, A. Malchiodi, G. Lauro, B.
Sacchetti, S. Paradisi, A. Ferroni, P. Curmi, S. Breit, M. Mazzanti, Journal of
Neuroscience 24 (2004) 5322–5330.
date_created: 2018-12-11T11:56:54Z
date_published: 2004-06-09T00:00:00Z
date_updated: 2021-01-12T06:56:41Z
day: '09'
doi: 10.1523/JNEUROSCI.1170-04.2004
extern: 1
intvolume: ' 24'
issue: '23'
month: '06'
page: 5322 - 5330
publication: Journal of Neuroscience
publication_status: published
publisher: Society for Neuroscience
publist_id: '4620'
quality_controlled: 0
status: public
title: Involvement of the intracellular ion channel CLIC1 in microglia-mediated β-amyloid-induced
neurotoxicity
type: journal_article
volume: 24
year: '2004'
...
---
_id: '2355'
abstract:
- lang: eng
text: 'The BMV conjecture for traces, which states that Tr exp(A - λB) is the Laplace
transform of a positive measure, is shown to be equivalent to two other statements:
(i) The polynomial λ → Tr(A + λB) p has only non-negative coefficients for all
A, B ≥ 0, p ∈ ℕ and (ii) λ → Tr(A + λB)-p is the Laplace transform of a positive
measure for A, B ≥ 0, p > 0.'
author:
- first_name: Élliott
full_name: Lieb, Élliott H
last_name: Lieb
- first_name: Robert
full_name: Robert Seiringer
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
citation:
ama: Lieb É, Seiringer R. Equivalent forms of the Bessis-Moussa-Villani conjecture.
Journal of Statistical Physics. 2004;115(1-2):185-190. doi:10.1023/B:JOSS.0000019811.15510.27
apa: Lieb, É., & Seiringer, R. (2004). Equivalent forms of the Bessis-Moussa-Villani
conjecture. Journal of Statistical Physics. Springer. https://doi.org/10.1023/B:JOSS.0000019811.15510.27
chicago: Lieb, Élliott, and Robert Seiringer. “ Equivalent Forms of the Bessis-Moussa-Villani
Conjecture.” Journal of Statistical Physics. Springer, 2004. https://doi.org/10.1023/B:JOSS.0000019811.15510.27.
ieee: É. Lieb and R. Seiringer, “ Equivalent forms of the Bessis-Moussa-Villani
conjecture,” Journal of Statistical Physics, vol. 115, no. 1–2. Springer,
pp. 185–190, 2004.
ista: Lieb É, Seiringer R. 2004. Equivalent forms of the Bessis-Moussa-Villani
conjecture. Journal of Statistical Physics. 115(1–2), 185–190.
mla: Lieb, Élliott, and Robert Seiringer. “ Equivalent Forms of the Bessis-Moussa-Villani
Conjecture.” Journal of Statistical Physics, vol. 115, no. 1–2, Springer,
2004, pp. 185–90, doi:10.1023/B:JOSS.0000019811.15510.27.
short: É. Lieb, R. Seiringer, Journal of Statistical Physics 115 (2004) 185–190.
date_created: 2018-12-11T11:57:11Z
date_published: 2004-04-01T00:00:00Z
date_updated: 2021-01-12T06:56:59Z
day: '01'
doi: 10.1023/B:JOSS.0000019811.15510.27
extern: 1
intvolume: ' 115'
issue: 1-2
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/math-ph/0210027
month: '04'
oa: 1
page: 185 - 190
publication: Journal of Statistical Physics
publication_status: published
publisher: Springer
publist_id: '4568'
quality_controlled: 0
status: public
title: ' Equivalent forms of the Bessis-Moussa-Villani conjecture'
type: journal_article
volume: 115
year: '2004'
...
---
_id: '2356'
abstract:
- lang: eng
text: 'Recent experimental and theoretical work has shown that there are conditions
in which a trapped, low-density Bose gas behaves like the one-dimensional delta-function
Bose gas solved years ago by Lieb and Liniger. This is an intrinsically quantum-mechanical
phenomenon because it is not necessary to have a trap width that is the size of
an atom - as might have been supposed - but it suffices merely to have a trap
width such that the energy gap for motion in the transverse direction is large
compared to the energy associated with the motion along the trap. Up to now the
theoretical arguments have been based on variational - perturbative ideas or numerical
investigations. In contrast, this paper gives a rigorous proof of the one-dimensional
behavior as far as the ground state energy and particle density are concerned.
There are four parameters involved: the particle number, N, transverse and longitudinal
dimensions of the trap, r and L, and the scattering length a of the interaction
potential. Our main result is that if r/L → 0 and N → ∞ the ground state energy
and density can be obtained by minimizing a one-dimensional density functional
involving the Lieb-Liniger energy density with coupling constant ∼ a/r 2. This
density functional simplifies in various limiting cases and we identify five asymptotic
parameter regions altogether. Three of these, corresponding to the weak coupling
regime, can also be obtained as limits of a three-dimensional Gross-Pitaevskii
theory. We also show that Bose-Einstein condensation in the ground state persists
in a part of this regime. In the strong coupling regime the longitudinal motion
of the particles is strongly correlated. The Gross-Pitaevskii description is not
valid in this regime and new mathematical methods come into play.'
author:
- first_name: Élliott
full_name: Lieb, Élliott H
last_name: Lieb
- first_name: Robert
full_name: Robert Seiringer
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
- first_name: Jakob
full_name: Yngvason, Jakob
last_name: Yngvason
citation:
ama: Lieb É, Seiringer R, Yngvason J. One-dimensional behavior of dilute, trapped
Bose gases. Communications in Mathematical Physics. 2004;244(2):347-393.
doi:10.1007/s00220-003-0993-3
apa: Lieb, É., Seiringer, R., & Yngvason, J. (2004). One-dimensional behavior
of dilute, trapped Bose gases. Communications in Mathematical Physics.
Springer. https://doi.org/10.1007/s00220-003-0993-3
chicago: Lieb, Élliott, Robert Seiringer, and Jakob Yngvason. “One-Dimensional Behavior
of Dilute, Trapped Bose Gases.” Communications in Mathematical Physics.
Springer, 2004. https://doi.org/10.1007/s00220-003-0993-3.
ieee: É. Lieb, R. Seiringer, and J. Yngvason, “One-dimensional behavior of dilute,
trapped Bose gases,” Communications in Mathematical Physics, vol. 244,
no. 2. Springer, pp. 347–393, 2004.
ista: Lieb É, Seiringer R, Yngvason J. 2004. One-dimensional behavior of dilute,
trapped Bose gases. Communications in Mathematical Physics. 244(2), 347–393.
mla: Lieb, Élliott, et al. “One-Dimensional Behavior of Dilute, Trapped Bose Gases.”
Communications in Mathematical Physics, vol. 244, no. 2, Springer, 2004,
pp. 347–93, doi:10.1007/s00220-003-0993-3.
short: É. Lieb, R. Seiringer, J. Yngvason, Communications in Mathematical Physics
244 (2004) 347–393.
date_created: 2018-12-11T11:57:11Z
date_published: 2004-01-01T00:00:00Z
date_updated: 2021-01-12T06:56:59Z
day: '01'
doi: 10.1007/s00220-003-0993-3
extern: 1
intvolume: ' 244'
issue: '2'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/math-ph/0305025
month: '01'
oa: 1
page: 347 - 393
publication: Communications in Mathematical Physics
publication_status: published
publisher: Springer
publist_id: '4569'
quality_controlled: 0
status: public
title: One-dimensional behavior of dilute, trapped Bose gases
type: journal_article
volume: 244
year: '2004'
...
---
_id: '2360'
abstract:
- lang: eng
text: An optical lattice model developed that is similar to the Bose-Hubbard model
to describe the transition between Bose-Einstein condensation (BEC) and a Mott
insulator state was analyzed. It was found that the system was a hard core lattice
gas at half of the maximum density and the optical lattice was modeled by a periodic
potential of strength λ. It was also observed that the interparticle interaction
was essential for this transition that occurred even in the ground state. The
results show that all the essential features could be proved rigorously such as
the existence of BEC for small λ and its suppression for a large λ.
author:
- first_name: Michael
full_name: Aizenman, Michael
last_name: Aizenman
- first_name: Élliott
full_name: Lieb, Élliott H
last_name: Lieb
- first_name: Robert
full_name: Robert Seiringer
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
- first_name: Jan
full_name: Solovej, Jan P
last_name: Solovej
- first_name: Jakob
full_name: Yngvason, Jakob
last_name: Yngvason
citation:
ama: Aizenman M, Lieb É, Seiringer R, Solovej J, Yngvason J. Bose-Einstein quantum
phase transition in an optical lattice model. Physical Review A - Atomic, Molecular,
and Optical Physics. 2004;70(2):023612-1-0236121-2. doi:10.1103/PhysRevA.70.023612
apa: Aizenman, M., Lieb, É., Seiringer, R., Solovej, J., & Yngvason, J. (2004).
Bose-Einstein quantum phase transition in an optical lattice model. Physical
Review A - Atomic, Molecular, and Optical Physics. American Physical Society.
https://doi.org/10.1103/PhysRevA.70.023612
chicago: Aizenman, Michael, Élliott Lieb, Robert Seiringer, Jan Solovej, and Jakob
Yngvason. “Bose-Einstein Quantum Phase Transition in an Optical Lattice Model.”
Physical Review A - Atomic, Molecular, and Optical Physics. American Physical
Society, 2004. https://doi.org/10.1103/PhysRevA.70.023612.
ieee: M. Aizenman, É. Lieb, R. Seiringer, J. Solovej, and J. Yngvason, “Bose-Einstein
quantum phase transition in an optical lattice model,” Physical Review A -
Atomic, Molecular, and Optical Physics, vol. 70, no. 2. American Physical
Society, pp. 023612-1-0236121-2, 2004.
ista: Aizenman M, Lieb É, Seiringer R, Solovej J, Yngvason J. 2004. Bose-Einstein
quantum phase transition in an optical lattice model. Physical Review A - Atomic,
Molecular, and Optical Physics. 70(2), 023612-1-0236121-2.
mla: Aizenman, Michael, et al. “Bose-Einstein Quantum Phase Transition in an Optical
Lattice Model.” Physical Review A - Atomic, Molecular, and Optical Physics,
vol. 70, no. 2, American Physical Society, 2004, pp. 023612-1-0236121-2, doi:10.1103/PhysRevA.70.023612.
short: M. Aizenman, É. Lieb, R. Seiringer, J. Solovej, J. Yngvason, Physical Review
A - Atomic, Molecular, and Optical Physics 70 (2004) 023612-1-0236121-2.
date_created: 2018-12-11T11:57:12Z
date_published: 2004-08-01T00:00:00Z
date_updated: 2021-01-12T06:57:01Z
day: '01'
doi: 10.1103/PhysRevA.70.023612
extern: 1
intvolume: ' 70'
issue: '2'
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/cond-mat/0403240
month: '08'
oa: 1
page: 023612 - 1-0236121-2
publication: Physical Review A - Atomic, Molecular, and Optical Physics
publication_status: published
publisher: American Physical Society
publist_id: '4567'
quality_controlled: 0
status: public
title: Bose-Einstein quantum phase transition in an optical lattice model
type: journal_article
volume: 70
year: '2004'
...
---
_id: '2417'
alternative_title:
- 'Contemporary Mathematics '
author:
- first_name: László
full_name: Lovász, László
last_name: Lovász
- first_name: Katalin
full_name: Vesztergombi, Katalin
last_name: Vesztergombi
- first_name: Uli
full_name: Uli Wagner
id: 36690CA2-F248-11E8-B48F-1D18A9856A87
last_name: Wagner
orcid: 0000-0002-1494-0568
- first_name: Emo
full_name: Welzl, Emo
last_name: Welzl
citation:
ama: 'Lovász L, Vesztergombi K, Wagner U, Welzl E. Convex quadrilaterals and k-sets
. In: Pach J, ed. Towards a Theory of Geometric Graphs. Vol 342. American
Mathematical Society; 2004:139-148. doi:10.1090/conm/342'
apa: Lovász, L., Vesztergombi, K., Wagner, U., & Welzl, E. (2004). Convex quadrilaterals
and k-sets . In J. Pach (Ed.), Towards a Theory of Geometric Graphs (Vol.
342, pp. 139–148). American Mathematical Society. https://doi.org/10.1090/conm/342
chicago: Lovász, László, Katalin Vesztergombi, Uli Wagner, and Emo Welzl. “Convex
Quadrilaterals and K-Sets .” In Towards a Theory of Geometric Graphs, edited
by János Pach, 342:139–48. American Mathematical Society, 2004. https://doi.org/10.1090/conm/342.
ieee: L. Lovász, K. Vesztergombi, U. Wagner, and E. Welzl, “Convex quadrilaterals
and k-sets ,” in Towards a Theory of Geometric Graphs, vol. 342, J. Pach,
Ed. American Mathematical Society, 2004, pp. 139–148.
ista: 'Lovász L, Vesztergombi K, Wagner U, Welzl E. 2004.Convex quadrilaterals and
k-sets . In: Towards a Theory of Geometric Graphs. Contemporary Mathematics ,
vol. 342, 139–148.'
mla: Lovász, László, et al. “Convex Quadrilaterals and K-Sets .” Towards a Theory
of Geometric Graphs, edited by János Pach, vol. 342, American Mathematical
Society, 2004, pp. 139–48, doi:10.1090/conm/342.
short: L. Lovász, K. Vesztergombi, U. Wagner, E. Welzl, in:, J. Pach (Ed.), Towards
a Theory of Geometric Graphs, American Mathematical Society, 2004, pp. 139–148.
date_created: 2018-12-11T11:57:32Z
date_published: 2004-01-01T00:00:00Z
date_updated: 2021-01-12T06:57:21Z
day: '01'
doi: 10.1090/conm/342
editor:
- first_name: János
full_name: Pach, János
last_name: Pach
extern: 1
intvolume: ' 342'
month: '01'
page: 139 - 148
publication: Towards a Theory of Geometric Graphs
publication_status: published
publisher: American Mathematical Society
publist_id: '4508'
quality_controlled: 0
status: public
title: 'Convex quadrilaterals and k-sets '
type: book_chapter
volume: 342
year: '2004'
...
---
_id: '2425'
abstract:
- lang: eng
text: A finite set N ⊂ Rd is a weak ε-net for an n-point set X ⊂ Rd (with respect
to convex sets) if N intersects every convex set K with |K ∩ X| ≥ εn. We give
an alternative, and arguably simpler, proof of the fact, first shown by Chazelle
et al., that every point set X in Rd admits a weak ε-net of cardinality O(ε-dpolylog(1/ε)).
Moreover, for a number of special point sets (e.g., for points on the moment curve),
our method gives substantially better bounds. The construction yields an algorithm
to construct such weak ε-nets in time O(n ln(1/ε)).
author:
- first_name: Jiří
full_name: Matoušek, Jiří
last_name: Matoušek
- first_name: Uli
full_name: Uli Wagner
id: 36690CA2-F248-11E8-B48F-1D18A9856A87
last_name: Wagner
orcid: 0000-0002-1494-0568
citation:
ama: Matoušek J, Wagner U. New constructions of weak ε-nets. Discrete & Computational
Geometry. 2004;32(2):195-206. doi:10.1007/s00454-004-1116-4
apa: Matoušek, J., & Wagner, U. (2004). New constructions of weak ε-nets. Discrete
& Computational Geometry. Springer. https://doi.org/10.1007/s00454-004-1116-4
chicago: Matoušek, Jiří, and Uli Wagner. “New Constructions of Weak ε-Nets.” Discrete
& Computational Geometry. Springer, 2004. https://doi.org/10.1007/s00454-004-1116-4.
ieee: J. Matoušek and U. Wagner, “New constructions of weak ε-nets,” Discrete
& Computational Geometry, vol. 32, no. 2. Springer, pp. 195–206, 2004.
ista: Matoušek J, Wagner U. 2004. New constructions of weak ε-nets. Discrete &
Computational Geometry. 32(2), 195–206.
mla: Matoušek, Jiří, and Uli Wagner. “New Constructions of Weak ε-Nets.” Discrete
& Computational Geometry, vol. 32, no. 2, Springer, 2004, pp. 195–206,
doi:10.1007/s00454-004-1116-4.
short: J. Matoušek, U. Wagner, Discrete & Computational Geometry 32 (2004) 195–206.
date_created: 2018-12-11T11:57:35Z
date_published: 2004-07-01T00:00:00Z
date_updated: 2021-01-12T06:57:24Z
day: '01'
doi: 10.1007/s00454-004-1116-4
extern: 1
intvolume: ' 32'
issue: '2'
month: '07'
page: 195 - 206
publication: Discrete & Computational Geometry
publication_status: published
publisher: Springer
publist_id: '4500'
quality_controlled: 0
status: public
title: New constructions of weak ε-nets
type: journal_article
volume: 32
year: '2004'
...
---
_id: '2426'
abstract:
- lang: eng
text: We introduce the adaptive neighborhood graph as a data structure for modeling
a smooth manifold M embedded in some Euclidean space ℝ d. We assume that M is
known to us only through a finite sample P ⊂ M, as is often the case in applications.
The adaptive neighborhood graph is a geometric graph on P. Its complexity is at
most min{2O(k)n, n2}, where n = P and k = dim M, as opposed to the n[d/2] complexity
of the Delaunay triangulation, which is often used to model manifolds. We prove
that we can correctly infer the connected components and the dimension of M from
the adaptive neighborhood graph provided a certain standard sampling condition
is fulfilled. The running time of the dimension detection algorithm is d20(k7
log k) for each connected component of M. If the dimension is considered constant,
this is a constant-time operation, and the adaptive neighborhood graph is of linear
size. Moreover, the exponential dependence of the constants is only on the intrinsic
dimension k, not on the ambient dimension d. This is of particular interest if
the co-dimension is high, i.e., if k is much smaller than d, as is the case in
many applications. The adaptive neighborhood graph also allows us to approximate
the geodesic distances between the points in P.
author:
- first_name: Joachim
full_name: Giesen, Joachim
last_name: Giesen
- first_name: Uli
full_name: Uli Wagner
id: 36690CA2-F248-11E8-B48F-1D18A9856A87
last_name: Wagner
orcid: 0000-0002-1494-0568
citation:
ama: Giesen J, Wagner U. Shape dimension and intrinsic metric from samples of manifolds.
Discrete & Computational Geometry. 2004;32(2):245-267. doi:10.1007/s00454-004-1120-8
apa: Giesen, J., & Wagner, U. (2004). Shape dimension and intrinsic metric from
samples of manifolds. Discrete & Computational Geometry. Springer.
https://doi.org/10.1007/s00454-004-1120-8
chicago: Giesen, Joachim, and Uli Wagner. “Shape Dimension and Intrinsic Metric
from Samples of Manifolds.” Discrete & Computational Geometry. Springer,
2004. https://doi.org/10.1007/s00454-004-1120-8.
ieee: J. Giesen and U. Wagner, “Shape dimension and intrinsic metric from samples
of manifolds,” Discrete & Computational Geometry, vol. 32, no. 2. Springer,
pp. 245–267, 2004.
ista: Giesen J, Wagner U. 2004. Shape dimension and intrinsic metric from samples
of manifolds. Discrete & Computational Geometry. 32(2), 245–267.
mla: Giesen, Joachim, and Uli Wagner. “Shape Dimension and Intrinsic Metric from
Samples of Manifolds.” Discrete & Computational Geometry, vol. 32,
no. 2, Springer, 2004, pp. 245–67, doi:10.1007/s00454-004-1120-8.
short: J. Giesen, U. Wagner, Discrete & Computational Geometry 32 (2004) 245–267.
date_created: 2018-12-11T11:57:35Z
date_published: 2004-09-01T00:00:00Z
date_updated: 2021-01-12T06:57:25Z
day: '01'
doi: 10.1007/s00454-004-1120-8
extern: 1
intvolume: ' 32'
issue: '2'
month: '09'
page: 245 - 267
publication: Discrete & Computational Geometry
publication_status: published
publisher: Springer
publist_id: '4499'
quality_controlled: 0
status: public
title: Shape dimension and intrinsic metric from samples of manifolds
type: journal_article
volume: 32
year: '2004'
...
---
_id: '2461'
author:
- first_name: Michael
full_name: Sauer, Michael
last_name: Sauer
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Sauer M, Friml J. The Matryoshka dolls of plant polarity. Development.
2004;131(23):5774-5775. doi:10.1242/dev.01463
apa: Sauer, M., & Friml, J. (2004). The Matryoshka dolls of plant polarity.
Development. Company of Biologists. https://doi.org/10.1242/dev.01463
chicago: Sauer, Michael, and Jiří Friml. “The Matryoshka Dolls of Plant Polarity.”
Development. Company of Biologists, 2004. https://doi.org/10.1242/dev.01463.
ieee: M. Sauer and J. Friml, “The Matryoshka dolls of plant polarity,” Development,
vol. 131, no. 23. Company of Biologists, pp. 5774–5775, 2004.
ista: Sauer M, Friml J. 2004. The Matryoshka dolls of plant polarity. Development.
131(23), 5774–5775.
mla: Sauer, Michael, and Jiří Friml. “The Matryoshka Dolls of Plant Polarity.” Development,
vol. 131, no. 23, Company of Biologists, 2004, pp. 5774–75, doi:10.1242/dev.01463.
short: M. Sauer, J. Friml, Development 131 (2004) 5774–5775.
date_created: 2018-12-11T11:57:48Z
date_published: 2004-12-01T00:00:00Z
date_updated: 2021-01-12T06:57:37Z
day: '01'
doi: 10.1242/dev.01463
extern: '1'
intvolume: ' 131'
issue: '23'
language:
- iso: eng
month: '12'
oa_version: None
page: 5774 - 5775
publication: Development
publication_status: published
publisher: Company of Biologists
publist_id: '4442'
quality_controlled: '1'
status: public
title: The Matryoshka dolls of plant polarity
type: review
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 131
year: '2004'
...
---
_id: '2636'
author:
- first_name: Akiko
full_name: Momiyama, Akiko
last_name: Momiyama
- first_name: Ryuichi
full_name: Ryuichi Shigemoto
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
citation:
ama: Momiyama A, Shigemoto R. Function and distribution of glutamate receptors in
the central synapses. Tanpakushitsu kakusan koso Protein nucleic acid enzyme.
2004;49(3 Suppl):287-294.
apa: Momiyama, A., & Shigemoto, R. (2004). Function and distribution of glutamate
receptors in the central synapses. Tanpakushitsu Kakusan Koso Protein Nucleic
Acid Enzyme. Kyoritsu Shuppan.
chicago: Momiyama, Akiko, and Ryuichi Shigemoto. “Function and Distribution of Glutamate
Receptors in the Central Synapses.” Tanpakushitsu Kakusan Koso Protein Nucleic
Acid Enzyme. Kyoritsu Shuppan, 2004.
ieee: A. Momiyama and R. Shigemoto, “Function and distribution of glutamate receptors
in the central synapses,” Tanpakushitsu kakusan koso Protein nucleic acid enzyme,
vol. 49, no. 3 Suppl. Kyoritsu Shuppan, pp. 287–294, 2004.
ista: Momiyama A, Shigemoto R. 2004. Function and distribution of glutamate receptors
in the central synapses. Tanpakushitsu kakusan koso Protein nucleic acid enzyme.
49(3 Suppl), 287–294.
mla: Momiyama, Akiko, and Ryuichi Shigemoto. “Function and Distribution of Glutamate
Receptors in the Central Synapses.” Tanpakushitsu Kakusan Koso Protein Nucleic
Acid Enzyme, vol. 49, no. 3 Suppl, Kyoritsu Shuppan, 2004, pp. 287–94.
short: A. Momiyama, R. Shigemoto, Tanpakushitsu Kakusan Koso Protein Nucleic Acid
Enzyme 49 (2004) 287–294.
date_created: 2018-12-11T11:58:48Z
date_published: 2004-02-01T00:00:00Z
date_updated: 2020-07-14T12:45:44Z
day: '01'
extern: 1
intvolume: ' 49'
issue: 3 Suppl
month: '02'
page: 287 - 294
publication: Tanpakushitsu kakusan koso Protein nucleic acid enzyme
publication_status: published
publisher: Kyoritsu Shuppan
publist_id: '4261'
quality_controlled: 0
status: public
title: Function and distribution of glutamate receptors in the central synapses
type: review
volume: 49
year: '2004'
...
---
_id: '2638'
abstract:
- lang: eng
text: Among various types of low- and high-threshold calcium channels, the high
voltage-activated P/Q-type channel is the most abundant in the cerebellum. These
P/Q-type channels are involved in the regulation of neurotransmitter release and
in the integration of dendritic inputs. We used an antibody specific for the α1A
subunit of the P/Q-type channel in quantitative pre-embedding immunogold labelling
combined with three-dimensional reconstruction to reveal the subcellular distribution
of pre- and postsynaptic P/Q-type channels in the rat cerebellum. At the light
microscopic level, immunoreactivity for the α1A protein was prevalent in the molecular
layer, whereas immunostaining was moderate in the somata of Purkinje cells and
weak in the granule cell layer. At the electron microscopic level, the most intense
Immunoreactivity for the α1A subunit was found in the presynaptic active zone
of parallel fibre varicosities. The dendritic spines of Purkinje cells were also
strongly labelled with the highest density of immunoparticles detected within
180 nm from the edge of the asymmetrical parallel fibre-Purkinje cell synapses.
By contrast, the immunolabelling was sparse in climbing fibre varicosities and
axon terminals of GABAergic cells, and weak and diffuse in dendritic shafts of
Purkinje cells. The association of the α1A subunit with the glutamatergic parallel
fibre-Purkinje cell synapses suggests that presynaptic channels have a major role
in the mediation of excitatory neurotransmission, whereas postsynaptic channels
are likely to be involved in depolarization-induced generation of local calcium
transients in Purkinje cells.
author:
- first_name: Ákos
full_name: Kulik, Ákos
last_name: Kulik
- first_name: Kazuhiko
full_name: Nakadate, Kazuhiko
last_name: Nakadate
- first_name: Akari
full_name: Hagiwara, Akari
last_name: Hagiwara
- first_name: Yugo
full_name: Fukazawa, Yugo
last_name: Fukazawa
- first_name: Rafael
full_name: Luján, Rafael
last_name: Luján
- first_name: Hiromitsu
full_name: Saito, Hiromitsu
last_name: Saito
- first_name: Noboru
full_name: Suzuki, Noboru
last_name: Suzuki
- first_name: Akira
full_name: Futatsugi, Akira
last_name: Futatsugi
- first_name: Katsuhiko
full_name: Mikoshiba, Katsuhiko
last_name: Mikoshiba
- first_name: Michael
full_name: Frotscher, Michael
last_name: Frotscher
- first_name: Ryuichi
full_name: Ryuichi Shigemoto
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
citation:
ama: Kulik Á, Nakadate K, Hagiwara A, et al. Immunocytochemical localization of
the α1A subunit of the P/Q-type calcium channel in the rat cerebellum. European
Journal of Neuroscience. 2004;19(8):2169-2178. doi:10.1111/j.0953-816X.2004.03319.x
apa: Kulik, Á., Nakadate, K., Hagiwara, A., Fukazawa, Y., Luján, R., Saito, H.,
… Shigemoto, R. (2004). Immunocytochemical localization of the α1A subunit of
the P/Q-type calcium channel in the rat cerebellum. European Journal of Neuroscience.
Wiley-Blackwell. https://doi.org/10.1111/j.0953-816X.2004.03319.x
chicago: Kulik, Ákos, Kazuhiko Nakadate, Akari Hagiwara, Yugo Fukazawa, Rafael Luján,
Hiromitsu Saito, Noboru Suzuki, et al. “Immunocytochemical Localization of the
Α1A Subunit of the P/Q-Type Calcium Channel in the Rat Cerebellum.” European
Journal of Neuroscience. Wiley-Blackwell, 2004. https://doi.org/10.1111/j.0953-816X.2004.03319.x.
ieee: Á. Kulik et al., “Immunocytochemical localization of the α1A subunit
of the P/Q-type calcium channel in the rat cerebellum,” European Journal of
Neuroscience, vol. 19, no. 8. Wiley-Blackwell, pp. 2169–2178, 2004.
ista: Kulik Á, Nakadate K, Hagiwara A, Fukazawa Y, Luján R, Saito H, Suzuki N, Futatsugi
A, Mikoshiba K, Frotscher M, Shigemoto R. 2004. Immunocytochemical localization
of the α1A subunit of the P/Q-type calcium channel in the rat cerebellum. European
Journal of Neuroscience. 19(8), 2169–2178.
mla: Kulik, Ákos, et al. “Immunocytochemical Localization of the Α1A Subunit of
the P/Q-Type Calcium Channel in the Rat Cerebellum.” European Journal of Neuroscience,
vol. 19, no. 8, Wiley-Blackwell, 2004, pp. 2169–78, doi:10.1111/j.0953-816X.2004.03319.x.
short: Á. Kulik, K. Nakadate, A. Hagiwara, Y. Fukazawa, R. Luján, H. Saito, N. Suzuki,
A. Futatsugi, K. Mikoshiba, M. Frotscher, R. Shigemoto, European Journal of Neuroscience
19 (2004) 2169–2178.
date_created: 2018-12-11T11:58:48Z
date_published: 2004-04-01T00:00:00Z
date_updated: 2021-01-12T06:58:44Z
day: '01'
doi: 10.1111/j.0953-816X.2004.03319.x
extern: 1
intvolume: ' 19'
issue: '8'
month: '04'
page: 2169 - 2178
publication: European Journal of Neuroscience
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4259'
quality_controlled: 0
status: public
title: Immunocytochemical localization of the α1A subunit of the P/Q-type calcium
channel in the rat cerebellum
type: journal_article
volume: 19
year: '2004'
...
---
_id: '2639'
abstract:
- lang: eng
text: Vesicular glutamate transporter type 3 (VGLUT3) containing neuronal elements
were characterized using antibodies to VGLUT3 and molecular cell markers. All
VGLUT3-positive somata were immunoreactive for CCK, and very rarely, also for
calbindin; none was positive for parvalbumin, calretinin, VIP or somatostatin.
In the CA1 area, 26.8 ± 0.7% of CCK-positive interneuron somata were VGLUT3-positive,
a nonoverlapping 22.8 ± 1.9% were calbindin-positive, 10.7 ± 2.5% VIP-positive
and the rest were only CCK-positive. The patterns of coexpression were similar
in the CA3 area, the dentate gyrus and the isocortex. Immunoreactivity for VGLUT3
was undetectable in pyramidal and dentate granule cells. Boutons colabelled for
VGLUT3, CCK and GAD were most abundant in the cellular layers of the hippocampus
and in layers II-III of the isocortex. Large VGLUT3-labelled boutons at the border
of strata radiatum and lacunosum-moleculare in the CA1 area were negative for
GAD, but were labelled for vesicular monoamine transporter type 2, plasmalemmal
serotonin transporter or serotonin. No colocalization was found in terminals between
VGLUT3 and parvalbumin, vesicular acetylcholine transporter and group III (mGluR7a,b;
mGluR8a,b) metabotropic glutamate receptors. In stratum radiatum and the isocortex,
VGLUT3-positive but GAD-negative boutons heavily innervated the soma and proximal
dendrites of some VGLUT3- or calbindin-positive interneurons. The results suggest
that boutons coexpressing VGLUT3, CCK and GAD originate from CCK-positive basket
cells, which are VIP-immunonegative. Other VGLUT3-positive boutons immunopositive
for serotonergic markers but negative for GAD probably originate from the median
raphe nucleus and innervate select interneurons. The presumed amino acid substrate
of VGLUT3 may act on presynaptic kainate or group II metabotropic glutamate receptors.
author:
- first_name: Jozsef
full_name: Somogyi, Jozsef
last_name: Somogyi
- first_name: Agnès
full_name: Baude, Agnès
last_name: Baude
- first_name: Yuko
full_name: Omori, Yuko
last_name: Omori
- first_name: Hidemi
full_name: Shimizu, Hidemi
last_name: Shimizu
- first_name: Salah
full_name: El-Mestikawy, Salah
last_name: El Mestikawy
- first_name: Masahiro
full_name: Fukaya, Masahiro
last_name: Fukaya
- first_name: Ryuichi
full_name: Ryuichi Shigemoto
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Masahiko
full_name: Watanabe, Masahiko
last_name: Watanabe
- first_name: Péter
full_name: Somogyi, Péter
last_name: Somogyi
citation:
ama: Somogyi J, Baude A, Omori Y, et al. GABAergic basket cells expressing cholecystokinin
contain vesicular glutamate transporter type 3 (VGLUT3) in their synaptic terminals
in hippocampus and isocortex of the rat. European Journal of Neuroscience.
2004;19(3):552-569. doi:10.1111/j.0953-816X.2003.03091.x
apa: Somogyi, J., Baude, A., Omori, Y., Shimizu, H., El Mestikawy, S., Fukaya, M.,
… Somogyi, P. (2004). GABAergic basket cells expressing cholecystokinin contain
vesicular glutamate transporter type 3 (VGLUT3) in their synaptic terminals in
hippocampus and isocortex of the rat. European Journal of Neuroscience.
Wiley-Blackwell. https://doi.org/10.1111/j.0953-816X.2003.03091.x
chicago: Somogyi, Jozsef, Agnès Baude, Yuko Omori, Hidemi Shimizu, Salah El Mestikawy,
Masahiro Fukaya, Ryuichi Shigemoto, Masahiko Watanabe, and Péter Somogyi. “GABAergic
Basket Cells Expressing Cholecystokinin Contain Vesicular Glutamate Transporter
Type 3 (VGLUT3) in Their Synaptic Terminals in Hippocampus and Isocortex of the
Rat.” European Journal of Neuroscience. Wiley-Blackwell, 2004. https://doi.org/10.1111/j.0953-816X.2003.03091.x.
ieee: J. Somogyi et al., “GABAergic basket cells expressing cholecystokinin
contain vesicular glutamate transporter type 3 (VGLUT3) in their synaptic terminals
in hippocampus and isocortex of the rat,” European Journal of Neuroscience,
vol. 19, no. 3. Wiley-Blackwell, pp. 552–569, 2004.
ista: Somogyi J, Baude A, Omori Y, Shimizu H, El Mestikawy S, Fukaya M, Shigemoto
R, Watanabe M, Somogyi P. 2004. GABAergic basket cells expressing cholecystokinin
contain vesicular glutamate transporter type 3 (VGLUT3) in their synaptic terminals
in hippocampus and isocortex of the rat. European Journal of Neuroscience. 19(3),
552–569.
mla: Somogyi, Jozsef, et al. “GABAergic Basket Cells Expressing Cholecystokinin
Contain Vesicular Glutamate Transporter Type 3 (VGLUT3) in Their Synaptic Terminals
in Hippocampus and Isocortex of the Rat.” European Journal of Neuroscience,
vol. 19, no. 3, Wiley-Blackwell, 2004, pp. 552–69, doi:10.1111/j.0953-816X.2003.03091.x.
short: J. Somogyi, A. Baude, Y. Omori, H. Shimizu, S. El Mestikawy, M. Fukaya, R.
Shigemoto, M. Watanabe, P. Somogyi, European Journal of Neuroscience 19 (2004)
552–569.
date_created: 2018-12-11T11:58:49Z
date_published: 2004-02-01T00:00:00Z
date_updated: 2021-01-12T06:58:44Z
day: '01'
doi: 10.1111/j.0953-816X.2003.03091.x
extern: 1
intvolume: ' 19'
issue: '3'
month: '02'
page: 552 - 569
publication: European Journal of Neuroscience
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4260'
quality_controlled: 0
status: public
title: GABAergic basket cells expressing cholecystokinin contain vesicular glutamate
transporter type 3 (VGLUT3) in their synaptic terminals in hippocampus and isocortex
of the rat
type: journal_article
volume: 19
year: '2004'
...