[{"date_published":"2004-07-13T00:00:00Z","publisher":"Elsevier","volume":14,"quality_controlled":"1","page":"1214-1220","extern":"1","department":[{"_id":"DaZi"}],"abstract":[{"lang":"eng","text":"In a number of organisms, transgenes containing transcribed inverted repeats (IRs) that produce hairpin RNA can trigger RNA-mediated silencing, which is associated with 21-24 nucleotide small interfering RNAs (siRNAs). In plants, IR-driven RNA silencing also causes extensive cytosine methylation of homologous DNA in both the transgene \"trigger\" and any other homologous DNA sequences--\"targets\". Endogenous genomic sequences, including transposable elements and repeated elements, are also subject to RNA-mediated silencing. The RNA silencing gene ARGONAUTE4 (AGO4) is required for maintenance of DNA methylation at several endogenous loci and for the establishment of methylation at the FWA gene. Here, we show that mutation of AGO4 substantially reduces the maintenance of DNA methylation triggered by IR transgenes, but AGO4 loss-of-function does not block the initiation of DNA methylation by IRs. AGO4 primarily affects non-CG methylation of the target sequences, while the IR trigger sequences lose methylation in all sequence contexts. Finally, we find that AGO4 and the DRM methyltransferase genes are required for maintenance of siRNAs at a subset of endogenous sequences, but AGO4 is not required for the accumulation of IR-induced siRNAs or a number of endogenous siRNAs, suggesting that AGO4 may function downstream of siRNA production."}],"external_id":{"pmid":["15242620 "]},"publication_status":"published","doi":"10.1016/j.cub.2004.06.055","article_type":"original","_id":"9493","year":"2004","citation":{"ama":"Zilberman D, Cao X, Johansen LK, Xie Z, Carrington JC, Jacobsen SE. Role of Arabidopsis ARGONAUTE4 in RNA-directed DNA methylation triggered by inverted repeats. <i>Current Biology</i>. 2004;14(13):1214-1220. doi:<a href=\"https://doi.org/10.1016/j.cub.2004.06.055\">10.1016/j.cub.2004.06.055</a>","ieee":"D. Zilberman, X. Cao, L. K. Johansen, Z. Xie, J. C. Carrington, and S. E. Jacobsen, “Role of Arabidopsis ARGONAUTE4 in RNA-directed DNA methylation triggered by inverted repeats,” <i>Current Biology</i>, vol. 14, no. 13. Elsevier, pp. 1214–1220, 2004.","short":"D. Zilberman, X. Cao, L.K. Johansen, Z. Xie, J.C. Carrington, S.E. Jacobsen, Current Biology 14 (2004) 1214–1220.","mla":"Zilberman, Daniel, et al. “Role of Arabidopsis ARGONAUTE4 in RNA-Directed DNA Methylation Triggered by Inverted Repeats.” <i>Current Biology</i>, vol. 14, no. 13, Elsevier, 2004, pp. 1214–20, doi:<a href=\"https://doi.org/10.1016/j.cub.2004.06.055\">10.1016/j.cub.2004.06.055</a>.","chicago":"Zilberman, Daniel, Xiaofeng Cao, Lisa K. Johansen, Zhixin Xie, James C. Carrington, and Steven E. Jacobsen. “Role of Arabidopsis ARGONAUTE4 in RNA-Directed DNA Methylation Triggered by Inverted Repeats.” <i>Current Biology</i>. Elsevier, 2004. <a href=\"https://doi.org/10.1016/j.cub.2004.06.055\">https://doi.org/10.1016/j.cub.2004.06.055</a>.","ista":"Zilberman D, Cao X, Johansen LK, Xie Z, Carrington JC, Jacobsen SE. 2004. Role of Arabidopsis ARGONAUTE4 in RNA-directed DNA methylation triggered by inverted repeats. Current Biology. 14(13), 1214–1220.","apa":"Zilberman, D., Cao, X., Johansen, L. K., Xie, Z., Carrington, J. C., &#38; Jacobsen, S. E. (2004). Role of Arabidopsis ARGONAUTE4 in RNA-directed DNA methylation triggered by inverted repeats. <i>Current Biology</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.cub.2004.06.055\">https://doi.org/10.1016/j.cub.2004.06.055</a>"},"date_created":"2021-06-07T10:33:00Z","type":"journal_article","status":"public","pmid":1,"month":"07","publication_identifier":{"eissn":["1879-0445"],"issn":["0960-9822"]},"user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","main_file_link":[{"url":"https://doi.org/10.1016/j.cub.2004.06.055","open_access":"1"}],"day":"13","oa_version":"Published Version","author":[{"first_name":"Daniel","full_name":"Zilberman, Daniel","orcid":"0000-0002-0123-8649","last_name":"Zilberman","id":"6973db13-dd5f-11ea-814e-b3e5455e9ed1"},{"last_name":"Cao","full_name":"Cao, Xiaofeng","first_name":"Xiaofeng"},{"full_name":"Johansen, Lisa K.","first_name":"Lisa K.","last_name":"Johansen"},{"first_name":"Zhixin","full_name":"Xie, Zhixin","last_name":"Xie"},{"last_name":"Carrington","first_name":"James C.","full_name":"Carrington, James C."},{"full_name":"Jacobsen, Steven E.","first_name":"Steven E.","last_name":"Jacobsen"}],"publication":"Current Biology","language":[{"iso":"eng"}],"intvolume":"        14","scopus_import":"1","issue":"13","article_processing_charge":"No","oa":1,"date_updated":"2021-12-14T08:52:00Z","title":"Role of Arabidopsis ARGONAUTE4 in RNA-directed DNA methylation triggered by inverted repeats"},{"extern":"1","department":[{"_id":"DaZi"}],"quality_controlled":"1","volume":5,"publisher":"Springer Nature","date_published":"2004-11-16T00:00:00Z","external_id":{"pmid":["15575975"]},"abstract":[{"lang":"eng","text":"Recent progress in understanding the silencing of transposable elements in the model plant Arabidopsis has revealed an interplay between DNA methylation, histone methylation and small interfering RNAs. DNA and histone methylation are not always sufficient to maintain silencing, and RNA-based reinforcement can be needed to maintain as well as initiate it."}],"publication_status":"published","doi":"10.1186/gb-2004-5-12-249","article_type":"review","_id":"9511","article_number":"249","citation":{"apa":"Zilberman, D., &#38; Henikoff, S. (2004). Silencing of transposons in plant genomes: kick them when they’re down. <i>Genome Biology</i>. Springer Nature. <a href=\"https://doi.org/10.1186/gb-2004-5-12-249\">https://doi.org/10.1186/gb-2004-5-12-249</a>","mla":"Zilberman, Daniel, and Steven Henikoff. “Silencing of Transposons in Plant Genomes: Kick Them When They’re Down.” <i>Genome Biology</i>, vol. 5, no. 12, 249, Springer Nature, 2004, doi:<a href=\"https://doi.org/10.1186/gb-2004-5-12-249\">10.1186/gb-2004-5-12-249</a>.","ista":"Zilberman D, Henikoff S. 2004. Silencing of transposons in plant genomes: kick them when they’re down. Genome Biology. 5(12), 249.","chicago":"Zilberman, Daniel, and Steven Henikoff. “Silencing of Transposons in Plant Genomes: Kick Them When They’re Down.” <i>Genome Biology</i>. Springer Nature, 2004. <a href=\"https://doi.org/10.1186/gb-2004-5-12-249\">https://doi.org/10.1186/gb-2004-5-12-249</a>.","short":"D. Zilberman, S. Henikoff, Genome Biology 5 (2004).","ieee":"D. Zilberman and S. Henikoff, “Silencing of transposons in plant genomes: kick them when they’re down,” <i>Genome Biology</i>, vol. 5, no. 12. Springer Nature, 2004.","ama":"Zilberman D, Henikoff S. Silencing of transposons in plant genomes: kick them when they’re down. <i>Genome Biology</i>. 2004;5(12). doi:<a href=\"https://doi.org/10.1186/gb-2004-5-12-249\">10.1186/gb-2004-5-12-249</a>"},"date_created":"2021-06-07T12:58:06Z","year":"2004","pmid":1,"status":"public","type":"journal_article","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1186/gb-2004-5-12-249"}],"oa_version":"Published Version","day":"16","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","publication_identifier":{"issn":["1474-760X"],"eissn":["1465-6906"]},"month":"11","author":[{"full_name":"Zilberman, Daniel","first_name":"Daniel","orcid":"0000-0002-0123-8649","last_name":"Zilberman","id":"6973db13-dd5f-11ea-814e-b3e5455e9ed1"},{"last_name":"Henikoff","full_name":"Henikoff, Steven","first_name":"Steven"}],"publication":"Genome Biology","language":[{"iso":"eng"}],"scopus_import":"1","intvolume":"         5","title":"Silencing of transposons in plant genomes: kick them when they're down","date_updated":"2021-12-14T08:44:24Z","oa":1,"article_processing_charge":"No","issue":"12"},{"_id":"9517","article_type":"original","doi":"10.1371/journal.pbio.0020104","citation":{"ista":"Xie Z, Johansen LK, Gustafson AM, Kasschau KD, Lellis AD, Zilberman D, Jacobsen SE, Carrington JC. 2004. Genetic and functional diversification of small RNA pathways in plants. PLoS Biology. 2(5), 0642–0652.","mla":"Xie, Zhixin, et al. “Genetic and Functional Diversification of Small RNA Pathways in Plants.” <i>PLoS Biology</i>, vol. 2, no. 5, Public Library of Science, 2004, pp. 0642–52, doi:<a href=\"https://doi.org/10.1371/journal.pbio.0020104\">10.1371/journal.pbio.0020104</a>.","chicago":"Xie, Zhixin, Lisa K. Johansen, Adam M. Gustafson, Kristin D. Kasschau, Andrew D.  Lellis, Daniel Zilberman, Steven E. Jacobsen, and James C. Carrington. “Genetic and Functional Diversification of Small RNA Pathways in Plants.” <i>PLoS Biology</i>. Public Library of Science, 2004. <a href=\"https://doi.org/10.1371/journal.pbio.0020104\">https://doi.org/10.1371/journal.pbio.0020104</a>.","ieee":"Z. Xie <i>et al.</i>, “Genetic and functional diversification of small RNA pathways in plants,” <i>PLoS Biology</i>, vol. 2, no. 5. Public Library of Science, pp. 0642–0652, 2004.","ama":"Xie Z, Johansen LK, Gustafson AM, et al. Genetic and functional diversification of small RNA pathways in plants. <i>PLoS Biology</i>. 2004;2(5):0642-0652. doi:<a href=\"https://doi.org/10.1371/journal.pbio.0020104\">10.1371/journal.pbio.0020104</a>","short":"Z. Xie, L.K. Johansen, A.M. Gustafson, K.D. Kasschau, A.D. Lellis, D. Zilberman, S.E. Jacobsen, J.C. Carrington, PLoS Biology 2 (2004) 0642–0652.","apa":"Xie, Z., Johansen, L. K., Gustafson, A. M., Kasschau, K. D., Lellis, A. D., Zilberman, D., … Carrington, J. C. (2004). Genetic and functional diversification of small RNA pathways in plants. <i>PLoS Biology</i>. Public Library of Science. <a href=\"https://doi.org/10.1371/journal.pbio.0020104\">https://doi.org/10.1371/journal.pbio.0020104</a>"},"date_created":"2021-06-07T14:12:08Z","year":"2004","quality_controlled":"1","volume":2,"extern":"1","page":"0642-0652","department":[{"_id":"DaZi"}],"date_published":"2004-02-24T00:00:00Z","publisher":"Public Library of Science","publication_status":"published","abstract":[{"lang":"eng","text":"Multicellular eukaryotes produce small RNA molecules (approximately 21–24 nucleotides) of two general types, microRNA (miRNA) and short interfering RNA (siRNA). They collectively function as sequence-specific guides to silence or regulate genes, transposons, and viruses and to modify chromatin and genome structure. Formation or activity of small RNAs requires factors belonging to gene families that encode DICER (or DICER-LIKE [DCL]) and ARGONAUTE proteins and, in the case of some siRNAs, RNA-dependent RNA polymerase (RDR) proteins. Unlike many animals, plants encode multiple DCL and RDR proteins. Using a series of insertion mutants of Arabidopsis thaliana, unique functions for three DCL proteins in miRNA (DCL1), endogenous siRNA (DCL3), and viral siRNA (DCL2) biogenesis were identified. One RDR protein (RDR2) was required for all endogenous siRNAs analyzed. The loss of endogenous siRNA in dcl3 and rdr2 mutants was associated with loss of heterochromatic marks and increased transcript accumulation at some loci. Defects in siRNA-generation activity in response to turnip crinkle virus in dcl2 mutant plants correlated with increased virus susceptibility. We conclude that proliferation and diversification of DCL and RDR genes during evolution of plants contributed to specialization of small RNA-directed pathways for development, chromatin structure, and defense."}],"external_id":{"pmid":["15024409"]},"language":[{"iso":"eng"}],"publication":"PLoS Biology","title":"Genetic and functional diversification of small RNA pathways in plants","article_processing_charge":"No","issue":"5","date_updated":"2021-12-14T08:43:57Z","oa":1,"intvolume":"         2","scopus_import":"1","type":"journal_article","status":"public","pmid":1,"author":[{"first_name":"Zhixin","full_name":"Xie, Zhixin","last_name":"Xie"},{"first_name":"Lisa K.","full_name":"Johansen, Lisa K.","last_name":"Johansen"},{"first_name":"Adam M.","full_name":"Gustafson, Adam M.","last_name":"Gustafson"},{"last_name":"Kasschau","first_name":"Kristin D.","full_name":"Kasschau, Kristin D."},{"full_name":"Lellis, Andrew D. ","first_name":"Andrew D. ","last_name":"Lellis"},{"first_name":"Daniel","full_name":"Zilberman, Daniel","orcid":"0000-0002-0123-8649","id":"6973db13-dd5f-11ea-814e-b3e5455e9ed1","last_name":"Zilberman"},{"first_name":"Steven E.","full_name":"Jacobsen, Steven E.","last_name":"Jacobsen"},{"last_name":"Carrington","full_name":"Carrington, James C.","first_name":"James C."}],"user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","oa_version":"Published Version","main_file_link":[{"url":"https://doi.org/10.1371/journal.pbio.0020104","open_access":"1"}],"day":"24","publication_identifier":{"eissn":["1545-7885"],"issn":["1544-9173"]},"month":"02"},{"article_processing_charge":"No","issue":"1","date_updated":"2023-02-10T07:47:21Z","oa":1,"title":"Algorithmic challenges in web search engines","scopus_import":"1","intvolume":"         1","language":[{"iso":"eng"}],"publication":"Internet Mathematics","author":[{"first_name":"Monika H","full_name":"Henzinger, Monika H","orcid":"0000-0002-5008-6530","last_name":"Henzinger","id":"540c9bbd-f2de-11ec-812d-d04a5be85630"}],"publication_identifier":{"eissn":["1944-9488"],"issn":["1542-7951"]},"month":"01","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","day":"01","oa_version":"Published Version","main_file_link":[{"url":"https://doi.org/10.1080/15427951.2004.10129079","open_access":"1"}],"type":"journal_article","status":"public","year":"2004","date_created":"2022-08-08T11:55:53Z","citation":{"apa":"Henzinger, M. H. (2004). Algorithmic challenges in web search engines. <i>Internet Mathematics</i>. Internet Mathematics. <a href=\"https://doi.org/10.1080/15427951.2004.10129079\">https://doi.org/10.1080/15427951.2004.10129079</a>","short":"M.H. Henzinger, Internet Mathematics 1 (2004) 115–123.","ieee":"M. H. Henzinger, “Algorithmic challenges in web search engines,” <i>Internet Mathematics</i>, vol. 1, no. 1. Internet Mathematics, pp. 115–123, 2004.","ama":"Henzinger MH. Algorithmic challenges in web search engines. <i>Internet Mathematics</i>. 2004;1(1):115-123. doi:<a href=\"https://doi.org/10.1080/15427951.2004.10129079\">10.1080/15427951.2004.10129079</a>","mla":"Henzinger, Monika H. “Algorithmic Challenges in Web Search Engines.” <i>Internet Mathematics</i>, vol. 1, no. 1, Internet Mathematics, 2004, pp. 115–23, doi:<a href=\"https://doi.org/10.1080/15427951.2004.10129079\">10.1080/15427951.2004.10129079</a>.","chicago":"Henzinger, Monika H. “Algorithmic Challenges in Web Search Engines.” <i>Internet Mathematics</i>. Internet Mathematics, 2004. <a href=\"https://doi.org/10.1080/15427951.2004.10129079\">https://doi.org/10.1080/15427951.2004.10129079</a>.","ista":"Henzinger MH. 2004. Algorithmic challenges in web search engines. Internet Mathematics. 1(1), 115–123."},"_id":"11762","article_type":"original","doi":"10.1080/15427951.2004.10129079","publication_status":"published","abstract":[{"lang":"eng","text":"In this paper, we describe six algorithmic problems that arise in web search engines and that are not or only partially solved: (1) Uniformly sampling of web pages; (2) modeling the web graph; (3) finding duplicate hosts; (4) finding top gainers and losers in data streams; (5) finding large dense bipartite graphs; and (6) understanding how eigenvectors partition the web."}],"date_published":"2004-01-01T00:00:00Z","publisher":"Internet Mathematics","quality_controlled":"1","volume":1,"extern":"1","page":"115-123"},{"author":[{"orcid":"0000-0002-5008-6530","id":"540c9bbd-f2de-11ec-812d-d04a5be85630","last_name":"Henzinger","full_name":"Henzinger, Monika H","first_name":"Monika H"}],"publication_status":"published","publication_identifier":{"issn":["0302-9743"],"eissn":["1611-3349"]},"month":"07","conference":{"location":"Turku, Finland","end_date":"2004-07-16","name":"ICALP: International Colloquium on Automata, Languages, and Programming","start_date":"2004-07-12"},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"text":"Web search engines have emerged as one of the central applications on the Internet. In fact, search has become one of the most important activities that people engage in on the the Internet. Even beyond becoming the number one source of information, a growing number of businesses are depending on web search engines for customer acquisition.\r\n\r\nThe first generation of web search engines used text-only retrieval techniques. Google revolutionized the field by deploying the PageRank technology – an eigenvector-based analysis of the hyperlink structure – to analyze the web in order to produce relevant results. Moving forward, our goal is to achieve a better understanding of a page with a view towards producing even more relevant results.","lang":"eng"}],"day":"01","oa_version":"None","type":"conference","date_published":"2004-07-01T00:00:00Z","status":"public","alternative_title":["LNCS"],"publisher":"Springer Nature","quality_controlled":"1","volume":3142,"extern":"1","page":"3","year":"2004","article_processing_charge":"No","date_updated":"2023-02-13T11:45:25Z","date_created":"2022-08-11T12:38:58Z","citation":{"apa":"Henzinger, M. H. (2004). The past, present, and future of web search engines. In <i>31st International Colloquium on Automata, Languages and Programming</i> (Vol. 3142, p. 3). Turku, Finland: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-540-27836-8_2\">https://doi.org/10.1007/978-3-540-27836-8_2</a>","short":"M.H. Henzinger, in:, 31st International Colloquium on Automata, Languages and Programming, Springer Nature, 2004, p. 3.","ieee":"M. H. Henzinger, “The past, present, and future of web search engines,” in <i>31st International Colloquium on Automata, Languages and Programming</i>, Turku, Finland, 2004, vol. 3142, p. 3.","ama":"Henzinger MH. The past, present, and future of web search engines. In: <i>31st International Colloquium on Automata, Languages and Programming</i>. Vol 3142. Springer Nature; 2004:3. doi:<a href=\"https://doi.org/10.1007/978-3-540-27836-8_2\">10.1007/978-3-540-27836-8_2</a>","mla":"Henzinger, Monika H. “The Past, Present, and Future of Web Search Engines.” <i>31st International Colloquium on Automata, Languages and Programming</i>, vol. 3142, Springer Nature, 2004, p. 3, doi:<a href=\"https://doi.org/10.1007/978-3-540-27836-8_2\">10.1007/978-3-540-27836-8_2</a>.","chicago":"Henzinger, Monika H. “The Past, Present, and Future of Web Search Engines.” In <i>31st International Colloquium on Automata, Languages and Programming</i>, 3142:3. Springer Nature, 2004. <a href=\"https://doi.org/10.1007/978-3-540-27836-8_2\">https://doi.org/10.1007/978-3-540-27836-8_2</a>.","ista":"Henzinger MH. 2004. The past, present, and future of web search engines. 31st International Colloquium on Automata, Languages and Programming. ICALP: International Colloquium on Automata, Languages, and Programming, LNCS, vol. 3142, 3."},"title":"The past, present, and future of web search engines","intvolume":"      3142","scopus_import":"1","language":[{"iso":"eng"}],"_id":"11800","publication":"31st International Colloquium on Automata, Languages and Programming","doi":"10.1007/978-3-540-27836-8_2"},{"language":[{"iso":"eng"}],"_id":"11801","doi":"10.1007/978-3-540-30140-0_2","publication":"2th Annual European Symposium on Algorithms","date_created":"2022-08-11T13:18:05Z","title":"Algorithmic aspects of web search engines","citation":{"apa":"Henzinger, M. H. (2004). Algorithmic aspects of web search engines. In <i>2th Annual European Symposium on Algorithms</i> (Vol. 3221, p. 3). Bergen, Norway: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-540-30140-0_2\">https://doi.org/10.1007/978-3-540-30140-0_2</a>","short":"M.H. Henzinger, in:, 2th Annual European Symposium on Algorithms, Springer Nature, 2004, p. 3.","ieee":"M. H. Henzinger, “Algorithmic aspects of web search engines,” in <i>2th Annual European Symposium on Algorithms</i>, Bergen, Norway, 2004, vol. 3221, p. 3.","ama":"Henzinger MH. Algorithmic aspects of web search engines. In: <i>2th Annual European Symposium on Algorithms</i>. Vol 3221. Springer Nature; 2004:3. doi:<a href=\"https://doi.org/10.1007/978-3-540-30140-0_2\">10.1007/978-3-540-30140-0_2</a>","ista":"Henzinger MH. 2004. Algorithmic aspects of web search engines. 2th Annual European Symposium on Algorithms. ESA: European Symposium on Algorithms, LNCS, vol. 3221, 3.","mla":"Henzinger, Monika H. “Algorithmic Aspects of Web Search Engines.” <i>2th Annual European Symposium on Algorithms</i>, vol. 3221, Springer Nature, 2004, p. 3, doi:<a href=\"https://doi.org/10.1007/978-3-540-30140-0_2\">10.1007/978-3-540-30140-0_2</a>.","chicago":"Henzinger, Monika H. “Algorithmic Aspects of Web Search Engines.” In <i>2th Annual European Symposium on Algorithms</i>, 3221:3. Springer Nature, 2004. <a href=\"https://doi.org/10.1007/978-3-540-30140-0_2\">https://doi.org/10.1007/978-3-540-30140-0_2</a>."},"year":"2004","article_processing_charge":"No","date_updated":"2023-02-13T11:47:26Z","scopus_import":"1","intvolume":"      3221","quality_controlled":"1","volume":3221,"extern":"1","page":"3","status":"public","type":"conference","date_published":"2004-09-01T00:00:00Z","publisher":"Springer Nature","alternative_title":["LNCS"],"publication_status":"published","author":[{"first_name":"Monika H","full_name":"Henzinger, Monika H","last_name":"Henzinger","id":"540c9bbd-f2de-11ec-812d-d04a5be85630","orcid":"0000-0002-5008-6530"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"text":"Web search engines have emerged as one of the central applications on the internet. In fact, search has become one of the most important activities that people engage in on the Internet. Even beyond becoming the number one source of information, a growing number of businesses are depending on web search engines for customer acquisition. In this talk I will brief review the history of web search engines: The first generation of web search engines used text-only retrieval techniques. Google revolutionized the field by deploying the PageRank technology – an eigenvector-based analysis of the hyperlink structure- to analyze the web in order to produce relevant results. Moving forward, our goal is to achieve a better understanding of a page with a view towards producing even more relevant results.\r\n\r\nGoogle is powered by a large number of PCs. Using this infrastructure and striving to be as efficient as possible poses challenging systems problems but also various algorithmic challenges. I will discuss some of them in my talk.","lang":"eng"}],"day":"01","oa_version":"None","publication_identifier":{"isbn":[" 3540230254"],"eissn":["1611-3349"],"issn":["0302-9743"]},"month":"09","conference":{"end_date":"2004-09-17","location":"Bergen, Norway","start_date":"2004-09-14","name":"ESA: European Symposium on Algorithms"}},{"publication":"SPIE Proceedings","doi":"10.1117/12.537534","language":[{"iso":"eng"}],"_id":"11859","scopus_import":"1","intvolume":"      5296","date_updated":"2023-02-17T10:05:19Z","article_processing_charge":"No","year":"2004","title":"The past, present, and future of web information retrieval","date_created":"2022-08-16T08:46:41Z","citation":{"apa":"Henzinger, M. H. (2004). The past, present, and future of web information retrieval. In <i>SPIE Proceedings</i> (Vol. 5296, pp. 23–26). San Jose, CA, United States: Society of Photo-Optical Instrumentation Engineers. <a href=\"https://doi.org/10.1117/12.537534\">https://doi.org/10.1117/12.537534</a>","chicago":"Henzinger, Monika H. “The Past, Present, and Future of Web Information Retrieval.” In <i>SPIE Proceedings</i>, 5296:23–26. Society of Photo-Optical Instrumentation Engineers, 2004. <a href=\"https://doi.org/10.1117/12.537534\">https://doi.org/10.1117/12.537534</a>.","ista":"Henzinger MH. 2004. The past, present, and future of web information retrieval. SPIE Proceedings. Document Recognition and Retrieval XI vol. 5296, 23–26.","mla":"Henzinger, Monika H. “The Past, Present, and Future of Web Information Retrieval.” <i>SPIE Proceedings</i>, vol. 5296, Society of Photo-Optical Instrumentation Engineers, 2004, pp. 23–26, doi:<a href=\"https://doi.org/10.1117/12.537534\">10.1117/12.537534</a>.","ieee":"M. H. Henzinger, “The past, present, and future of web information retrieval,” in <i>SPIE Proceedings</i>, San Jose, CA, United States, 2004, vol. 5296, pp. 23–26.","ama":"Henzinger MH. The past, present, and future of web information retrieval. In: <i>SPIE Proceedings</i>. Vol 5296. Society of Photo-Optical Instrumentation Engineers; 2004:23-26. doi:<a href=\"https://doi.org/10.1117/12.537534\">10.1117/12.537534</a>","short":"M.H. Henzinger, in:, SPIE Proceedings, Society of Photo-Optical Instrumentation Engineers, 2004, pp. 23–26."},"publisher":"Society of Photo-Optical Instrumentation Engineers","status":"public","type":"conference","date_published":"2004-01-01T00:00:00Z","page":"23 - 26","extern":"1","volume":5296,"quality_controlled":"1","conference":{"start_date":"2004-01-21","name":"Document Recognition and Retrieval XI","end_date":"2004-01-22","location":"San Jose, CA, United States"},"month":"01","publication_identifier":{"issn":["0277-786X"]},"oa_version":"None","day":"01","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"text":"In this article we describe the approach taken by the first web search engines, discuss the state of the art, and present some of the challenges for the future.","lang":"eng"}],"publication_status":"published","author":[{"orcid":"0000-0002-5008-6530","id":"540c9bbd-f2de-11ec-812d-d04a5be85630","last_name":"Henzinger","first_name":"Monika H","full_name":"Henzinger, Monika H"}]},{"status":"public","type":"journal_article","pmid":1,"author":[{"last_name":"Henzinger","id":"540c9bbd-f2de-11ec-812d-d04a5be85630","orcid":"0000-0002-5008-6530","first_name":"Monika H","full_name":"Henzinger, Monika H"},{"first_name":"Steve","full_name":"Lawrence, Steve","last_name":"Lawrence"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","main_file_link":[{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC387294/","open_access":"1"}],"day":"06","oa_version":"Published Version","month":"04","publication_identifier":{"eissn":["1091-6490"],"issn":["0027-8424"]},"language":[{"iso":"eng"}],"publication":"Proceedings of the National Academy of Sciences","title":"Extracting knowledge from the World Wide Web","article_processing_charge":"No","issue":"suppl_1","date_updated":"2023-02-17T12:21:43Z","oa":1,"scopus_import":"1","intvolume":"       101","volume":101,"quality_controlled":"1","page":"5186-5191","extern":"1","date_published":"2004-04-06T00:00:00Z","publisher":"Proceedings of the National Academy of Sciences","publication_status":"published","abstract":[{"lang":"eng","text":"The World Wide Web provides a unprecedented opportunity to automatically analyze a large sample of interests and activity in the world. We discuss methods for extracting knowledge from the web by randomly sampling and analyzing hosts and pages, and by analyzing the link structure of the web and how links accumulate over time. A variety of interesting and valuable information can be extracted, such as the distribution of web pages over domains, the distribution of interest in different areas, communities related to different topics, the nature of competition in different categories of sites, and the degree of communication between different communities or countries."}],"external_id":{"pmid":["14745041"]},"_id":"11877","article_type":"original","doi":"10.1073/pnas.0307528100","date_created":"2022-08-16T13:06:10Z","citation":{"mla":"Henzinger, Monika H., and Steve Lawrence. “Extracting Knowledge from the World Wide Web.” <i>Proceedings of the National Academy of Sciences</i>, vol. 101, no. suppl_1, Proceedings of the National Academy of Sciences, 2004, pp. 5186–91, doi:<a href=\"https://doi.org/10.1073/pnas.0307528100\">10.1073/pnas.0307528100</a>.","ista":"Henzinger MH, Lawrence S. 2004. Extracting knowledge from the World Wide Web. Proceedings of the National Academy of Sciences. 101(suppl_1), 5186–5191.","chicago":"Henzinger, Monika H, and Steve Lawrence. “Extracting Knowledge from the World Wide Web.” <i>Proceedings of the National Academy of Sciences</i>. Proceedings of the National Academy of Sciences, 2004. <a href=\"https://doi.org/10.1073/pnas.0307528100\">https://doi.org/10.1073/pnas.0307528100</a>.","short":"M.H. Henzinger, S. Lawrence, Proceedings of the National Academy of Sciences 101 (2004) 5186–5191.","ama":"Henzinger MH, Lawrence S. Extracting knowledge from the World Wide Web. <i>Proceedings of the National Academy of Sciences</i>. 2004;101(suppl_1):5186-5191. doi:<a href=\"https://doi.org/10.1073/pnas.0307528100\">10.1073/pnas.0307528100</a>","ieee":"M. H. Henzinger and S. Lawrence, “Extracting knowledge from the World Wide Web,” <i>Proceedings of the National Academy of Sciences</i>, vol. 101, no. suppl_1. Proceedings of the National Academy of Sciences, pp. 5186–5191, 2004.","apa":"Henzinger, M. H., &#38; Lawrence, S. (2004). Extracting knowledge from the World Wide Web. <i>Proceedings of the National Academy of Sciences</i>. Proceedings of the National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.0307528100\">https://doi.org/10.1073/pnas.0307528100</a>"},"year":"2004"},{"day":"17","month":"03","publication_status":"published","author":[{"last_name":"Browning","id":"35827D50-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8314-0177","first_name":"Timothy D","full_name":"Timothy Browning"},{"last_name":"Heath Brown","first_name":"Roger","full_name":"Heath-Brown, Roger"}],"quality_controlled":0,"volume":157,"page":"553 - 573","extern":1,"type":"journal_article","status":"public","date_published":"2004-03-17T00:00:00Z","publisher":"Unknown","intvolume":"       157","title":"Equal sums of three powers","date_created":"2018-12-11T11:45:13Z","publist_id":"7703","citation":{"apa":"Browning, T. D., &#38; Heath Brown, R. (2004). Equal sums of three powers. <i>Inventiones Mathematicae</i>. Unknown. <a href=\"https://doi.org/10.1007/s00222-004-0360-9\">https://doi.org/10.1007/s00222-004-0360-9</a>","ista":"Browning TD, Heath Brown R. 2004. Equal sums of three powers. Inventiones Mathematicae. 157(3), 553–573.","mla":"Browning, Timothy D., and Roger Heath Brown. “Equal Sums of Three Powers.” <i>Inventiones Mathematicae</i>, vol. 157, no. 3, Unknown, 2004, pp. 553–73, doi:<a href=\"https://doi.org/10.1007/s00222-004-0360-9\">10.1007/s00222-004-0360-9</a>.","chicago":"Browning, Timothy D, and Roger Heath Brown. “Equal Sums of Three Powers.” <i>Inventiones Mathematicae</i>. Unknown, 2004. <a href=\"https://doi.org/10.1007/s00222-004-0360-9\">https://doi.org/10.1007/s00222-004-0360-9</a>.","ieee":"T. D. Browning and R. Heath Brown, “Equal sums of three powers,” <i>Inventiones Mathematicae</i>, vol. 157, no. 3. Unknown, pp. 553–573, 2004.","ama":"Browning TD, Heath Brown R. Equal sums of three powers. <i>Inventiones Mathematicae</i>. 2004;157(3):553-573. doi:<a href=\"https://doi.org/10.1007/s00222-004-0360-9\">10.1007/s00222-004-0360-9</a>","short":"T.D. Browning, R. Heath Brown, Inventiones Mathematicae 157 (2004) 553–573."},"issue":"3","year":"2004","date_updated":"2021-01-12T06:55:14Z","doi":"10.1007/s00222-004-0360-9","publication":"Inventiones Mathematicae","_id":"209"},{"_id":"2308","publication":"Journal of Neuroscience","doi":"10.1523/JNEUROSCI.1170-04.2004","year":"2004","issue":"23","date_updated":"2021-01-12T06:56:41Z","date_created":"2018-12-11T11:56:54Z","citation":{"apa":"Novarino, G., Fabrizi, C., Tonini, R., Denti, M., Malchiodi, A., Lauro, G., … Mazzanti, M. (2004). Involvement of the intracellular ion channel CLIC1 in microglia-mediated β-amyloid-induced neurotoxicity. <i>Journal of Neuroscience</i>. Society for Neuroscience. <a href=\"https://doi.org/10.1523/JNEUROSCI.1170-04.2004\">https://doi.org/10.1523/JNEUROSCI.1170-04.2004</a>","chicago":"Novarino, Gaia, Cinzia Fabrizi, Raffaella Tonini, Michela Denti, Albedi Malchiodi, Giuliana Lauro, Benedetto Sacchetti, et al. “Involvement of the Intracellular Ion Channel CLIC1 in Microglia-Mediated β-Amyloid-Induced Neurotoxicity.” <i>Journal of Neuroscience</i>. Society for Neuroscience, 2004. <a href=\"https://doi.org/10.1523/JNEUROSCI.1170-04.2004\">https://doi.org/10.1523/JNEUROSCI.1170-04.2004</a>.","mla":"Novarino, Gaia, et al. “Involvement of the Intracellular Ion Channel CLIC1 in Microglia-Mediated β-Amyloid-Induced Neurotoxicity.” <i>Journal of Neuroscience</i>, vol. 24, no. 23, Society for Neuroscience, 2004, pp. 5322–30, doi:<a href=\"https://doi.org/10.1523/JNEUROSCI.1170-04.2004\">10.1523/JNEUROSCI.1170-04.2004</a>.","ista":"Novarino G, Fabrizi C, Tonini R, Denti M, Malchiodi A, Lauro G, Sacchetti B, Paradisi S, Ferroni A, Curmi P, Breit S, Mazzanti M. 2004. Involvement of the intracellular ion channel CLIC1 in microglia-mediated β-amyloid-induced neurotoxicity. Journal of Neuroscience. 24(23), 5322–5330.","short":"G. Novarino, C. Fabrizi, R. Tonini, M. Denti, A. Malchiodi, G. Lauro, B. Sacchetti, S. Paradisi, A. Ferroni, P. Curmi, S. Breit, M. Mazzanti, Journal of Neuroscience 24 (2004) 5322–5330.","ama":"Novarino G, Fabrizi C, Tonini R, et al. Involvement of the intracellular ion channel CLIC1 in microglia-mediated β-amyloid-induced neurotoxicity. <i>Journal of Neuroscience</i>. 2004;24(23):5322-5330. doi:<a href=\"https://doi.org/10.1523/JNEUROSCI.1170-04.2004\">10.1523/JNEUROSCI.1170-04.2004</a>","ieee":"G. Novarino <i>et al.</i>, “Involvement of the intracellular ion channel CLIC1 in microglia-mediated β-amyloid-induced neurotoxicity,” <i>Journal of Neuroscience</i>, vol. 24, no. 23. Society for Neuroscience, pp. 5322–5330, 2004."},"title":"Involvement of the intracellular ion channel CLIC1 in microglia-mediated β-amyloid-induced neurotoxicity","publist_id":"4620","intvolume":"        24","date_published":"2004-06-09T00:00:00Z","status":"public","type":"journal_article","publisher":"Society for Neuroscience","quality_controlled":0,"volume":24,"page":"5322 - 5330","extern":1,"author":[{"full_name":"Gaia Novarino","first_name":"Gaia","orcid":"0000-0002-7673-7178","id":"3E57A680-F248-11E8-B48F-1D18A9856A87","last_name":"Novarino"},{"last_name":"Fabrizi","first_name":"Cinzia","full_name":"Fabrizi, Cinzia"},{"last_name":"Tonini","first_name":"Raffaella","full_name":"Tonini, Raffaella"},{"first_name":"Michela","full_name":"Denti, Michela A","last_name":"Denti"},{"first_name":"Albedi","full_name":"Malchiodi, Albedi F","last_name":"Malchiodi"},{"last_name":"Lauro","first_name":"Giuliana","full_name":"Lauro, Giuliana M"},{"first_name":"Benedetto","full_name":"Sacchetti, Benedetto","last_name":"Sacchetti"},{"last_name":"Paradisi","full_name":"Paradisi, Silvia","first_name":"Silvia"},{"first_name":"Arnaldo","full_name":"Ferroni, Arnaldo","last_name":"Ferroni"},{"last_name":"Curmi","full_name":"Curmi, Paul M G","first_name":"Paul"},{"last_name":"Breit","first_name":"Samuel","full_name":"Breit, Samuel N"},{"first_name":"Michele","full_name":"Mazzanti, Michele","last_name":"Mazzanti"}],"publication_status":"published","month":"06","abstract":[{"text":"It is widely believed that the inflammatory events mediated by microglial activation contribute to several neurodegenerative processes. Alzheimer's disease, for example, is characterized by an accumulation of β-amyloid protein (Aβ) in neuritic plaques that are infiltrated by reactive microglia and astrocytes. Although Aβ and its fragment 25-35 exert a direct toxic effect on neurons, they also activate microglia. Microglial activation is accompanied by morphological changes, cell proliferation, and release of various cytokines and growth factors. A number of scientific reports suggest that the increased proliferation of microglial cells is dependent on ionic membrane currents and in particular on chloride conductances. An unusual chloride ion channel known to be associated with macrophage activation is the chloride intracellular channel-1 (CLIC1). Here we show that Aβ stimulation of neonatal rat microglia specifically leads to the increase in CLIC1 protein and to the functional expression of CLIC1 chloride conductance, both barely detectable on the plasma membrane of quiescent cells. CLIC1 protein expression in microglia increases after 24 hr of incubation with Aβ, simultaneously with the production of reactive nitrogen intermediates and of tumor necrosis factor-α (TNF-α). We demonstrate that reducing CLIC1 chloride conductance by a specific blocker [IAA-94 (R(+)-[(6,7-dichloro-2-cyclopentyl-2,3-dihydro-2-methyl-1-oxo-1H-inden-5yl)-oxy] acetic acid)] prevents neuronal apoptosis in neurons cocultured with Aβ-treated microglia. Furthermore, we show that small interfering RNAs used to knock down CLIC1 expression prevent TNF-α release induced by Aβ stimulation. These results provide a direct link between Aβ-induced microglial activation and CLIC1 functional expression.","lang":"eng"}],"day":"09"},{"date_created":"2018-12-11T11:57:11Z","title":" Equivalent forms of the Bessis-Moussa-Villani conjecture","publist_id":"4568","citation":{"ista":"Lieb É, Seiringer R. 2004.  Equivalent forms of the Bessis-Moussa-Villani conjecture. Journal of Statistical Physics. 115(1–2), 185–190.","chicago":"Lieb, Élliott, and Robert Seiringer. “ Equivalent Forms of the Bessis-Moussa-Villani Conjecture.” <i>Journal of Statistical Physics</i>. Springer, 2004. <a href=\"https://doi.org/10.1023/B:JOSS.0000019811.15510.27\">https://doi.org/10.1023/B:JOSS.0000019811.15510.27</a>.","mla":"Lieb, Élliott, and Robert Seiringer. “ Equivalent Forms of the Bessis-Moussa-Villani Conjecture.” <i>Journal of Statistical Physics</i>, vol. 115, no. 1–2, Springer, 2004, pp. 185–90, doi:<a href=\"https://doi.org/10.1023/B:JOSS.0000019811.15510.27\">10.1023/B:JOSS.0000019811.15510.27</a>.","short":"É. Lieb, R. Seiringer, Journal of Statistical Physics 115 (2004) 185–190.","ieee":"É. Lieb and R. Seiringer, “ Equivalent forms of the Bessis-Moussa-Villani conjecture,” <i>Journal of Statistical Physics</i>, vol. 115, no. 1–2. Springer, pp. 185–190, 2004.","ama":"Lieb É, Seiringer R.  Equivalent forms of the Bessis-Moussa-Villani conjecture. <i>Journal of Statistical Physics</i>. 2004;115(1-2):185-190. doi:<a href=\"https://doi.org/10.1023/B:JOSS.0000019811.15510.27\">10.1023/B:JOSS.0000019811.15510.27</a>","apa":"Lieb, É., &#38; Seiringer, R. (2004).  Equivalent forms of the Bessis-Moussa-Villani conjecture. <i>Journal of Statistical Physics</i>. Springer. <a href=\"https://doi.org/10.1023/B:JOSS.0000019811.15510.27\">https://doi.org/10.1023/B:JOSS.0000019811.15510.27</a>"},"year":"2004","issue":"1-2","oa":1,"date_updated":"2021-01-12T06:56:59Z","intvolume":"       115","_id":"2355","doi":"10.1023/B:JOSS.0000019811.15510.27","publication":"Journal of Statistical Physics","author":[{"last_name":"Lieb","full_name":"Lieb, Élliott H","first_name":"Élliott"},{"full_name":"Robert Seiringer","first_name":"Robert","id":"4AFD0470-F248-11E8-B48F-1D18A9856A87","last_name":"Seiringer","orcid":"0000-0002-6781-0521"}],"publication_status":"published","abstract":[{"lang":"eng","text":"The BMV conjecture for traces, which states that Tr exp(A - λB) is the Laplace transform of a positive measure, is shown to be equivalent to two other statements: (i) The polynomial λ → Tr(A + λB) p has only non-negative coefficients for all A, B ≥ 0, p ∈ ℕ and (ii) λ → Tr(A + λB)-p is the Laplace transform of a positive measure for A, B ≥ 0, p &gt; 0."}],"main_file_link":[{"open_access":"1","url":"http://arxiv.org/abs/math-ph/0210027"}],"day":"01","month":"04","volume":115,"quality_controlled":0,"extern":1,"page":"185 - 190","date_published":"2004-04-01T00:00:00Z","type":"journal_article","status":"public","publisher":"Springer"},{"day":"01","main_file_link":[{"open_access":"1","url":"http://arxiv.org/abs/math-ph/0305025"}],"abstract":[{"lang":"eng","text":"Recent experimental and theoretical work has shown that there are conditions in which a trapped, low-density Bose gas behaves like the one-dimensional delta-function Bose gas solved years ago by Lieb and Liniger. This is an intrinsically quantum-mechanical phenomenon because it is not necessary to have a trap width that is the size of an atom - as might have been supposed - but it suffices merely to have a trap width such that the energy gap for motion in the transverse direction is large compared to the energy associated with the motion along the trap. Up to now the theoretical arguments have been based on variational - perturbative ideas or numerical investigations. In contrast, this paper gives a rigorous proof of the one-dimensional behavior as far as the ground state energy and particle density are concerned. There are four parameters involved: the particle number, N, transverse and longitudinal dimensions of the trap, r and L, and the scattering length a of the interaction potential. Our main result is that if r/L → 0 and N → ∞ the ground state energy and density can be obtained by minimizing a one-dimensional density functional involving the Lieb-Liniger energy density with coupling constant ∼ a/r 2. This density functional simplifies in various limiting cases and we identify five asymptotic parameter regions altogether. Three of these, corresponding to the weak coupling regime, can also be obtained as limits of a three-dimensional Gross-Pitaevskii theory. We also show that Bose-Einstein condensation in the ground state persists in a part of this regime. In the strong coupling regime the longitudinal motion of the particles is strongly correlated. The Gross-Pitaevskii description is not valid in this regime and new mathematical methods come into play."}],"month":"01","publication_status":"published","author":[{"last_name":"Lieb","full_name":"Lieb, Élliott H","first_name":"Élliott"},{"last_name":"Seiringer","id":"4AFD0470-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6781-0521","full_name":"Robert Seiringer","first_name":"Robert"},{"last_name":"Yngvason","full_name":"Yngvason, Jakob","first_name":"Jakob"}],"page":"347 - 393","extern":1,"quality_controlled":0,"volume":244,"publisher":"Springer","type":"journal_article","status":"public","date_published":"2004-01-01T00:00:00Z","intvolume":"       244","publist_id":"4569","date_created":"2018-12-11T11:57:11Z","title":"One-dimensional behavior of dilute, trapped Bose gases","citation":{"apa":"Lieb, É., Seiringer, R., &#38; Yngvason, J. (2004). One-dimensional behavior of dilute, trapped Bose gases. <i>Communications in Mathematical Physics</i>. Springer. <a href=\"https://doi.org/10.1007/s00220-003-0993-3\">https://doi.org/10.1007/s00220-003-0993-3</a>","ista":"Lieb É, Seiringer R, Yngvason J. 2004. One-dimensional behavior of dilute, trapped Bose gases. Communications in Mathematical Physics. 244(2), 347–393.","mla":"Lieb, Élliott, et al. “One-Dimensional Behavior of Dilute, Trapped Bose Gases.” <i>Communications in Mathematical Physics</i>, vol. 244, no. 2, Springer, 2004, pp. 347–93, doi:<a href=\"https://doi.org/10.1007/s00220-003-0993-3\">10.1007/s00220-003-0993-3</a>.","chicago":"Lieb, Élliott, Robert Seiringer, and Jakob Yngvason. “One-Dimensional Behavior of Dilute, Trapped Bose Gases.” <i>Communications in Mathematical Physics</i>. Springer, 2004. <a href=\"https://doi.org/10.1007/s00220-003-0993-3\">https://doi.org/10.1007/s00220-003-0993-3</a>.","short":"É. Lieb, R. Seiringer, J. Yngvason, Communications in Mathematical Physics 244 (2004) 347–393.","ieee":"É. Lieb, R. Seiringer, and J. Yngvason, “One-dimensional behavior of dilute, trapped Bose gases,” <i>Communications in Mathematical Physics</i>, vol. 244, no. 2. Springer, pp. 347–393, 2004.","ama":"Lieb É, Seiringer R, Yngvason J. One-dimensional behavior of dilute, trapped Bose gases. <i>Communications in Mathematical Physics</i>. 2004;244(2):347-393. doi:<a href=\"https://doi.org/10.1007/s00220-003-0993-3\">10.1007/s00220-003-0993-3</a>"},"date_updated":"2021-01-12T06:56:59Z","oa":1,"issue":"2","year":"2004","doi":"10.1007/s00220-003-0993-3","publication":"Communications in Mathematical Physics","_id":"2356"},{"intvolume":"        70","publist_id":"4567","title":"Bose-Einstein quantum phase transition in an optical lattice model","date_created":"2018-12-11T11:57:12Z","citation":{"apa":"Aizenman, M., Lieb, É., Seiringer, R., Solovej, J., &#38; Yngvason, J. (2004). Bose-Einstein quantum phase transition in an optical lattice model. <i>Physical Review A - Atomic, Molecular, and Optical Physics</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevA.70.023612\">https://doi.org/10.1103/PhysRevA.70.023612</a>","mla":"Aizenman, Michael, et al. “Bose-Einstein Quantum Phase Transition in an Optical Lattice Model.” <i>Physical Review A - Atomic, Molecular, and Optical Physics</i>, vol. 70, no. 2, American Physical Society, 2004, pp. 023612-1-0236121-2, doi:<a href=\"https://doi.org/10.1103/PhysRevA.70.023612\">10.1103/PhysRevA.70.023612</a>.","ista":"Aizenman M, Lieb É, Seiringer R, Solovej J, Yngvason J. 2004. Bose-Einstein quantum phase transition in an optical lattice model. Physical Review A - Atomic, Molecular, and Optical Physics. 70(2), 023612-1-0236121-2.","chicago":"Aizenman, Michael, Élliott Lieb, Robert Seiringer, Jan Solovej, and Jakob Yngvason. “Bose-Einstein Quantum Phase Transition in an Optical Lattice Model.” <i>Physical Review A - Atomic, Molecular, and Optical Physics</i>. American Physical Society, 2004. <a href=\"https://doi.org/10.1103/PhysRevA.70.023612\">https://doi.org/10.1103/PhysRevA.70.023612</a>.","short":"M. Aizenman, É. Lieb, R. Seiringer, J. Solovej, J. Yngvason, Physical Review A - Atomic, Molecular, and Optical Physics 70 (2004) 023612-1-0236121-2.","ama":"Aizenman M, Lieb É, Seiringer R, Solovej J, Yngvason J. Bose-Einstein quantum phase transition in an optical lattice model. <i>Physical Review A - Atomic, Molecular, and Optical Physics</i>. 2004;70(2):023612-1-0236121-2. doi:<a href=\"https://doi.org/10.1103/PhysRevA.70.023612\">10.1103/PhysRevA.70.023612</a>","ieee":"M. Aizenman, É. Lieb, R. Seiringer, J. Solovej, and J. Yngvason, “Bose-Einstein quantum phase transition in an optical lattice model,” <i>Physical Review A - Atomic, Molecular, and Optical Physics</i>, vol. 70, no. 2. American Physical Society, pp. 023612-1-0236121-2, 2004."},"oa":1,"date_updated":"2021-01-12T06:57:01Z","issue":"2","year":"2004","doi":"10.1103/PhysRevA.70.023612","publication":"Physical Review A - Atomic, Molecular, and Optical Physics","_id":"2360","day":"01","main_file_link":[{"open_access":"1","url":"http://arxiv.org/abs/cond-mat/0403240"}],"abstract":[{"lang":"eng","text":"An optical lattice model developed that is similar to the Bose-Hubbard model to describe the transition between Bose-Einstein condensation (BEC) and a Mott insulator state was analyzed. It was found that the system was a hard core lattice gas at half of the maximum density and the optical lattice was modeled by a periodic potential of strength λ. It was also observed that the interparticle interaction was essential for this transition that occurred even in the ground state. The results show that all the essential features could be proved rigorously such as the existence of BEC for small λ and its suppression for a large λ."}],"month":"08","publication_status":"published","author":[{"last_name":"Aizenman","full_name":"Aizenman, Michael","first_name":"Michael"},{"last_name":"Lieb","first_name":"Élliott","full_name":"Lieb, Élliott H"},{"first_name":"Robert","full_name":"Robert Seiringer","last_name":"Seiringer","id":"4AFD0470-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6781-0521"},{"last_name":"Solovej","first_name":"Jan","full_name":"Solovej, Jan P"},{"full_name":"Yngvason, Jakob","first_name":"Jakob","last_name":"Yngvason"}],"page":"023612 - 1-0236121-2","extern":1,"volume":70,"quality_controlled":0,"publisher":"American Physical Society","date_published":"2004-08-01T00:00:00Z","status":"public","type":"journal_article"},{"date_published":"2004-01-01T00:00:00Z","type":"book_chapter","status":"public","alternative_title":["Contemporary Mathematics "],"publisher":"American Mathematical Society","volume":342,"quality_controlled":0,"extern":1,"page":"139 - 148","author":[{"full_name":"Lovász, László","first_name":"László","last_name":"Lovász"},{"last_name":"Vesztergombi","first_name":"Katalin","full_name":"Vesztergombi, Katalin"},{"orcid":"0000-0002-1494-0568","id":"36690CA2-F248-11E8-B48F-1D18A9856A87","last_name":"Wagner","full_name":"Uli Wagner","first_name":"Uli"},{"full_name":"Welzl, Emo","first_name":"Emo","last_name":"Welzl"}],"publication_status":"published","month":"01","day":"01","_id":"2417","publication":"Towards a Theory of Geometric Graphs","doi":"10.1090/conm/342","year":"2004","date_updated":"2021-01-12T06:57:21Z","date_created":"2018-12-11T11:57:32Z","title":"Convex quadrilaterals and k-sets ","publist_id":"4508","citation":{"mla":"Lovász, László, et al. “Convex Quadrilaterals and K-Sets .” <i>Towards a Theory of Geometric Graphs</i>, edited by János Pach, vol. 342, American Mathematical Society, 2004, pp. 139–48, doi:<a href=\"https://doi.org/10.1090/conm/342\">10.1090/conm/342</a>.","chicago":"Lovász, László, Katalin Vesztergombi, Uli Wagner, and Emo Welzl. “Convex Quadrilaterals and K-Sets .” In <i>Towards a Theory of Geometric Graphs</i>, edited by János Pach, 342:139–48. American Mathematical Society, 2004. <a href=\"https://doi.org/10.1090/conm/342\">https://doi.org/10.1090/conm/342</a>.","ista":"Lovász L, Vesztergombi K, Wagner U, Welzl E. 2004.Convex quadrilaterals and k-sets . In: Towards a Theory of Geometric Graphs. Contemporary Mathematics , vol. 342, 139–148.","ieee":"L. Lovász, K. Vesztergombi, U. Wagner, and E. Welzl, “Convex quadrilaterals and k-sets ,” in <i>Towards a Theory of Geometric Graphs</i>, vol. 342, J. Pach, Ed. American Mathematical Society, 2004, pp. 139–148.","ama":"Lovász L, Vesztergombi K, Wagner U, Welzl E. Convex quadrilaterals and k-sets . In: Pach J, ed. <i>Towards a Theory of Geometric Graphs</i>. Vol 342. American Mathematical Society; 2004:139-148. doi:<a href=\"https://doi.org/10.1090/conm/342\">10.1090/conm/342</a>","short":"L. Lovász, K. Vesztergombi, U. Wagner, E. Welzl, in:, J. Pach (Ed.), Towards a Theory of Geometric Graphs, American Mathematical Society, 2004, pp. 139–148.","apa":"Lovász, L., Vesztergombi, K., Wagner, U., &#38; Welzl, E. (2004). Convex quadrilaterals and k-sets . In J. Pach (Ed.), <i>Towards a Theory of Geometric Graphs</i> (Vol. 342, pp. 139–148). American Mathematical Society. <a href=\"https://doi.org/10.1090/conm/342\">https://doi.org/10.1090/conm/342</a>"},"editor":[{"first_name":"János","full_name":"Pach, János","last_name":"Pach"}],"intvolume":"       342"},{"year":"2004","issue":"2","date_updated":"2021-01-12T06:57:24Z","date_created":"2018-12-11T11:57:35Z","citation":{"ieee":"J. Matoušek and U. Wagner, “New constructions of weak ε-nets,” <i>Discrete &#38; Computational Geometry</i>, vol. 32, no. 2. Springer, pp. 195–206, 2004.","ama":"Matoušek J, Wagner U. New constructions of weak ε-nets. <i>Discrete &#38; Computational Geometry</i>. 2004;32(2):195-206. doi:<a href=\"https://doi.org/10.1007/s00454-004-1116-4\">10.1007/s00454-004-1116-4</a>","short":"J. Matoušek, U. Wagner, Discrete &#38; Computational Geometry 32 (2004) 195–206.","mla":"Matoušek, Jiří, and Uli Wagner. “New Constructions of Weak ε-Nets.” <i>Discrete &#38; Computational Geometry</i>, vol. 32, no. 2, Springer, 2004, pp. 195–206, doi:<a href=\"https://doi.org/10.1007/s00454-004-1116-4\">10.1007/s00454-004-1116-4</a>.","ista":"Matoušek J, Wagner U. 2004. New constructions of weak ε-nets. Discrete &#38; Computational Geometry. 32(2), 195–206.","chicago":"Matoušek, Jiří, and Uli Wagner. “New Constructions of Weak ε-Nets.” <i>Discrete &#38; Computational Geometry</i>. Springer, 2004. <a href=\"https://doi.org/10.1007/s00454-004-1116-4\">https://doi.org/10.1007/s00454-004-1116-4</a>.","apa":"Matoušek, J., &#38; Wagner, U. (2004). New constructions of weak ε-nets. <i>Discrete &#38; Computational Geometry</i>. Springer. <a href=\"https://doi.org/10.1007/s00454-004-1116-4\">https://doi.org/10.1007/s00454-004-1116-4</a>"},"publist_id":"4500","title":"New constructions of weak ε-nets","intvolume":"        32","_id":"2425","publication":"Discrete & Computational Geometry","doi":"10.1007/s00454-004-1116-4","author":[{"last_name":"Matoušek","full_name":"Matoušek, Jiří","first_name":"Jiří"},{"last_name":"Wagner","id":"36690CA2-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-1494-0568","first_name":"Uli","full_name":"Uli Wagner"}],"publication_status":"published","month":"07","abstract":[{"lang":"eng","text":"A finite set N ⊂ Rd is a weak ε-net for an n-point set X ⊂ Rd (with respect to convex sets) if N intersects every convex set K with |K ∩ X| ≥ εn. We give an alternative, and arguably simpler, proof of the fact, first shown by Chazelle et al., that every point set X in Rd admits a weak ε-net of cardinality O(ε-dpolylog(1/ε)). Moreover, for a number of special point sets (e.g., for points on the moment curve), our method gives substantially better bounds. The construction yields an algorithm to construct such weak ε-nets in time O(n ln(1/ε))."}],"day":"01","date_published":"2004-07-01T00:00:00Z","type":"journal_article","status":"public","publisher":"Springer","volume":32,"quality_controlled":0,"extern":1,"page":"195 - 206"},{"publication_status":"published","author":[{"last_name":"Giesen","full_name":"Giesen, Joachim","first_name":"Joachim"},{"first_name":"Uli","full_name":"Uli Wagner","orcid":"0000-0002-1494-0568","last_name":"Wagner","id":"36690CA2-F248-11E8-B48F-1D18A9856A87"}],"month":"09","day":"01","abstract":[{"lang":"eng","text":"We introduce the adaptive neighborhood graph as a data structure for modeling a smooth manifold M embedded in some Euclidean space ℝ d. We assume that M is known to us only through a finite sample P ⊂ M, as is often the case in applications. The adaptive neighborhood graph is a geometric graph on P. Its complexity is at most min{2O(k)n, n2}, where n = P and k = dim M, as opposed to the n[d/2] complexity of the Delaunay triangulation, which is often used to model manifolds. We prove that we can correctly infer the connected components and the dimension of M from the adaptive neighborhood graph provided a certain standard sampling condition is fulfilled. The running time of the dimension detection algorithm is d20(k7 log k) for each connected component of M. If the dimension is considered constant, this is a constant-time operation, and the adaptive neighborhood graph is of linear size. Moreover, the exponential dependence of the constants is only on the intrinsic dimension k, not on the ambient dimension d. This is of particular interest if the co-dimension is high, i.e., if k is much smaller than d, as is the case in many applications. The adaptive neighborhood graph also allows us to approximate the geodesic distances between the points in P."}],"publisher":"Springer","status":"public","date_published":"2004-09-01T00:00:00Z","type":"journal_article","page":"245 - 267","extern":1,"quality_controlled":0,"volume":32,"date_updated":"2021-01-12T06:57:25Z","year":"2004","issue":"2","citation":{"apa":"Giesen, J., &#38; Wagner, U. (2004). Shape dimension and intrinsic metric from samples of manifolds. <i>Discrete &#38; Computational Geometry</i>. Springer. <a href=\"https://doi.org/10.1007/s00454-004-1120-8\">https://doi.org/10.1007/s00454-004-1120-8</a>","short":"J. Giesen, U. Wagner, Discrete &#38; Computational Geometry 32 (2004) 245–267.","ieee":"J. Giesen and U. Wagner, “Shape dimension and intrinsic metric from samples of manifolds,” <i>Discrete &#38; Computational Geometry</i>, vol. 32, no. 2. Springer, pp. 245–267, 2004.","ama":"Giesen J, Wagner U. Shape dimension and intrinsic metric from samples of manifolds. <i>Discrete &#38; Computational Geometry</i>. 2004;32(2):245-267. doi:<a href=\"https://doi.org/10.1007/s00454-004-1120-8\">10.1007/s00454-004-1120-8</a>","mla":"Giesen, Joachim, and Uli Wagner. “Shape Dimension and Intrinsic Metric from Samples of Manifolds.” <i>Discrete &#38; Computational Geometry</i>, vol. 32, no. 2, Springer, 2004, pp. 245–67, doi:<a href=\"https://doi.org/10.1007/s00454-004-1120-8\">10.1007/s00454-004-1120-8</a>.","ista":"Giesen J, Wagner U. 2004. Shape dimension and intrinsic metric from samples of manifolds. Discrete &#38; Computational Geometry. 32(2), 245–267.","chicago":"Giesen, Joachim, and Uli Wagner. “Shape Dimension and Intrinsic Metric from Samples of Manifolds.” <i>Discrete &#38; Computational Geometry</i>. Springer, 2004. <a href=\"https://doi.org/10.1007/s00454-004-1120-8\">https://doi.org/10.1007/s00454-004-1120-8</a>."},"title":"Shape dimension and intrinsic metric from samples of manifolds","publist_id":"4499","date_created":"2018-12-11T11:57:35Z","intvolume":"        32","_id":"2426","publication":"Discrete & Computational Geometry","doi":"10.1007/s00454-004-1120-8"},{"publisher":"Company of Biologists","status":"public","type":"review","date_published":"2004-12-01T00:00:00Z","extern":"1","page":"5774 - 5775","quality_controlled":"1","volume":131,"publication_status":"published","author":[{"first_name":"Michael","full_name":"Sauer, Michael","last_name":"Sauer"},{"orcid":"0000-0002-8302-7596","last_name":"Friml","id":"4159519E-F248-11E8-B48F-1D18A9856A87","full_name":"Friml, Jirí","first_name":"Jirí"}],"month":"12","day":"01","oa_version":"None","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","language":[{"iso":"eng"}],"_id":"2461","publication":"Development","doi":"10.1242/dev.01463","date_updated":"2021-01-12T06:57:37Z","issue":"23","year":"2004","publist_id":"4442","title":"The Matryoshka dolls of plant polarity","citation":{"short":"M. Sauer, J. Friml, Development 131 (2004) 5774–5775.","ieee":"M. Sauer and J. Friml, “The Matryoshka dolls of plant polarity,” <i>Development</i>, vol. 131, no. 23. Company of Biologists, pp. 5774–5775, 2004.","ama":"Sauer M, Friml J. The Matryoshka dolls of plant polarity. <i>Development</i>. 2004;131(23):5774-5775. doi:<a href=\"https://doi.org/10.1242/dev.01463\">10.1242/dev.01463</a>","ista":"Sauer M, Friml J. 2004. The Matryoshka dolls of plant polarity. Development. 131(23), 5774–5775.","mla":"Sauer, Michael, and Jiří Friml. “The Matryoshka Dolls of Plant Polarity.” <i>Development</i>, vol. 131, no. 23, Company of Biologists, 2004, pp. 5774–75, doi:<a href=\"https://doi.org/10.1242/dev.01463\">10.1242/dev.01463</a>.","chicago":"Sauer, Michael, and Jiří Friml. “The Matryoshka Dolls of Plant Polarity.” <i>Development</i>. Company of Biologists, 2004. <a href=\"https://doi.org/10.1242/dev.01463\">https://doi.org/10.1242/dev.01463</a>.","apa":"Sauer, M., &#38; Friml, J. (2004). The Matryoshka dolls of plant polarity. <i>Development</i>. Company of Biologists. <a href=\"https://doi.org/10.1242/dev.01463\">https://doi.org/10.1242/dev.01463</a>"},"date_created":"2018-12-11T11:57:48Z","intvolume":"       131"},{"publisher":"Kyoritsu Shuppan","status":"public","type":"review","date_published":"2004-02-01T00:00:00Z","page":"287 - 294","extern":1,"quality_controlled":0,"volume":49,"month":"02","day":"01","publication_status":"published","author":[{"last_name":"Momiyama","full_name":"Momiyama, Akiko","first_name":"Akiko"},{"id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","last_name":"Shigemoto","orcid":"0000-0001-8761-9444","first_name":"Ryuichi","full_name":"Ryuichi Shigemoto"}],"publication":"Tanpakushitsu kakusan koso Protein nucleic acid enzyme","_id":"2636","intvolume":"        49","date_updated":"2020-07-14T12:45:44Z","year":"2004","issue":"3 Suppl","date_created":"2018-12-11T11:58:48Z","title":"Function and distribution of glutamate receptors in the central synapses","publist_id":"4261","citation":{"mla":"Momiyama, Akiko, and Ryuichi Shigemoto. “Function and Distribution of Glutamate Receptors in the Central Synapses.” <i>Tanpakushitsu Kakusan Koso Protein Nucleic Acid Enzyme</i>, vol. 49, no. 3 Suppl, Kyoritsu Shuppan, 2004, pp. 287–94.","ista":"Momiyama A, Shigemoto R. 2004. Function and distribution of glutamate receptors in the central synapses. Tanpakushitsu kakusan koso Protein nucleic acid enzyme. 49(3 Suppl), 287–294.","chicago":"Momiyama, Akiko, and Ryuichi Shigemoto. “Function and Distribution of Glutamate Receptors in the Central Synapses.” <i>Tanpakushitsu Kakusan Koso Protein Nucleic Acid Enzyme</i>. Kyoritsu Shuppan, 2004.","short":"A. Momiyama, R. Shigemoto, Tanpakushitsu Kakusan Koso Protein Nucleic Acid Enzyme 49 (2004) 287–294.","ama":"Momiyama A, Shigemoto R. Function and distribution of glutamate receptors in the central synapses. <i>Tanpakushitsu kakusan koso Protein nucleic acid enzyme</i>. 2004;49(3 Suppl):287-294.","ieee":"A. Momiyama and R. Shigemoto, “Function and distribution of glutamate receptors in the central synapses,” <i>Tanpakushitsu kakusan koso Protein nucleic acid enzyme</i>, vol. 49, no. 3 Suppl. Kyoritsu Shuppan, pp. 287–294, 2004.","apa":"Momiyama, A., &#38; Shigemoto, R. (2004). Function and distribution of glutamate receptors in the central synapses. <i>Tanpakushitsu Kakusan Koso Protein Nucleic Acid Enzyme</i>. Kyoritsu Shuppan."}},{"extern":1,"page":"2169 - 2178","volume":19,"quality_controlled":0,"publisher":"Wiley-Blackwell","status":"public","date_published":"2004-04-01T00:00:00Z","type":"journal_article","author":[{"full_name":"Kulik, Ákos","first_name":"Ákos","last_name":"Kulik"},{"last_name":"Nakadate","first_name":"Kazuhiko","full_name":"Nakadate, Kazuhiko"},{"last_name":"Hagiwara","first_name":"Akari","full_name":"Hagiwara, Akari"},{"full_name":"Fukazawa, Yugo","first_name":"Yugo","last_name":"Fukazawa"},{"last_name":"Luján","full_name":"Luján, Rafael","first_name":"Rafael"},{"full_name":"Saito, Hiromitsu","first_name":"Hiromitsu","last_name":"Saito"},{"last_name":"Suzuki","first_name":"Noboru","full_name":"Suzuki, Noboru"},{"last_name":"Futatsugi","first_name":"Akira","full_name":"Futatsugi, Akira"},{"last_name":"Mikoshiba","first_name":"Katsuhiko","full_name":"Mikoshiba, Katsuhiko"},{"full_name":"Frotscher, Michael","first_name":"Michael","last_name":"Frotscher"},{"first_name":"Ryuichi","full_name":"Ryuichi Shigemoto","last_name":"Shigemoto","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8761-9444"}],"publication_status":"published","day":"01","abstract":[{"lang":"eng","text":"Among various types of low- and high-threshold calcium channels, the high voltage-activated P/Q-type channel is the most abundant in the cerebellum. These P/Q-type channels are involved in the regulation of neurotransmitter release and in the integration of dendritic inputs. We used an antibody specific for the α1A subunit of the P/Q-type channel in quantitative pre-embedding immunogold labelling combined with three-dimensional reconstruction to reveal the subcellular distribution of pre- and postsynaptic P/Q-type channels in the rat cerebellum. At the light microscopic level, immunoreactivity for the α1A protein was prevalent in the molecular layer, whereas immunostaining was moderate in the somata of Purkinje cells and weak in the granule cell layer. At the electron microscopic level, the most intense Immunoreactivity for the α1A subunit was found in the presynaptic active zone of parallel fibre varicosities. The dendritic spines of Purkinje cells were also strongly labelled with the highest density of immunoparticles detected within 180 nm from the edge of the asymmetrical parallel fibre-Purkinje cell synapses. By contrast, the immunolabelling was sparse in climbing fibre varicosities and axon terminals of GABAergic cells, and weak and diffuse in dendritic shafts of Purkinje cells. The association of the α1A subunit with the glutamatergic parallel fibre-Purkinje cell synapses suggests that presynaptic channels have a major role in the mediation of excitatory neurotransmission, whereas postsynaptic channels are likely to be involved in depolarization-induced generation of local calcium transients in Purkinje cells."}],"month":"04","_id":"2638","doi":"10.1111/j.0953-816X.2004.03319.x","publication":"European Journal of Neuroscience","citation":{"apa":"Kulik, Á., Nakadate, K., Hagiwara, A., Fukazawa, Y., Luján, R., Saito, H., … Shigemoto, R. (2004). Immunocytochemical localization of the α1A subunit of the P/Q-type calcium channel in the rat cerebellum. <i>European Journal of Neuroscience</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1111/j.0953-816X.2004.03319.x\">https://doi.org/10.1111/j.0953-816X.2004.03319.x</a>","short":"Á. Kulik, K. Nakadate, A. Hagiwara, Y. Fukazawa, R. Luján, H. Saito, N. Suzuki, A. Futatsugi, K. Mikoshiba, M. Frotscher, R. Shigemoto, European Journal of Neuroscience 19 (2004) 2169–2178.","ama":"Kulik Á, Nakadate K, Hagiwara A, et al. Immunocytochemical localization of the α1A subunit of the P/Q-type calcium channel in the rat cerebellum. <i>European Journal of Neuroscience</i>. 2004;19(8):2169-2178. doi:<a href=\"https://doi.org/10.1111/j.0953-816X.2004.03319.x\">10.1111/j.0953-816X.2004.03319.x</a>","ieee":"Á. Kulik <i>et al.</i>, “Immunocytochemical localization of the α1A subunit of the P/Q-type calcium channel in the rat cerebellum,” <i>European Journal of Neuroscience</i>, vol. 19, no. 8. Wiley-Blackwell, pp. 2169–2178, 2004.","chicago":"Kulik, Ákos, Kazuhiko Nakadate, Akari Hagiwara, Yugo Fukazawa, Rafael Luján, Hiromitsu Saito, Noboru Suzuki, et al. “Immunocytochemical Localization of the Α1A Subunit of the P/Q-Type Calcium Channel in the Rat Cerebellum.” <i>European Journal of Neuroscience</i>. Wiley-Blackwell, 2004. <a href=\"https://doi.org/10.1111/j.0953-816X.2004.03319.x\">https://doi.org/10.1111/j.0953-816X.2004.03319.x</a>.","ista":"Kulik Á, Nakadate K, Hagiwara A, Fukazawa Y, Luján R, Saito H, Suzuki N, Futatsugi A, Mikoshiba K, Frotscher M, Shigemoto R. 2004. Immunocytochemical localization of the α1A subunit of the P/Q-type calcium channel in the rat cerebellum. European Journal of Neuroscience. 19(8), 2169–2178.","mla":"Kulik, Ákos, et al. “Immunocytochemical Localization of the Α1A Subunit of the P/Q-Type Calcium Channel in the Rat Cerebellum.” <i>European Journal of Neuroscience</i>, vol. 19, no. 8, Wiley-Blackwell, 2004, pp. 2169–78, doi:<a href=\"https://doi.org/10.1111/j.0953-816X.2004.03319.x\">10.1111/j.0953-816X.2004.03319.x</a>."},"date_created":"2018-12-11T11:58:48Z","title":"Immunocytochemical localization of the α1A subunit of the P/Q-type calcium channel in the rat cerebellum","publist_id":"4259","date_updated":"2021-01-12T06:58:44Z","issue":"8","year":"2004","intvolume":"        19"},{"volume":19,"quality_controlled":0,"extern":1,"page":"552 - 569","date_published":"2004-02-01T00:00:00Z","type":"journal_article","status":"public","publisher":"Wiley-Blackwell","abstract":[{"lang":"eng","text":"Vesicular glutamate transporter type 3 (VGLUT3) containing neuronal elements were characterized using antibodies to VGLUT3 and molecular cell markers. All VGLUT3-positive somata were immunoreactive for CCK, and very rarely, also for calbindin; none was positive for parvalbumin, calretinin, VIP or somatostatin. In the CA1 area, 26.8 ± 0.7% of CCK-positive interneuron somata were VGLUT3-positive, a nonoverlapping 22.8 ± 1.9% were calbindin-positive, 10.7 ± 2.5% VIP-positive and the rest were only CCK-positive. The patterns of coexpression were similar in the CA3 area, the dentate gyrus and the isocortex. Immunoreactivity for VGLUT3 was undetectable in pyramidal and dentate granule cells. Boutons colabelled for VGLUT3, CCK and GAD were most abundant in the cellular layers of the hippocampus and in layers II-III of the isocortex. Large VGLUT3-labelled boutons at the border of strata radiatum and lacunosum-moleculare in the CA1 area were negative for GAD, but were labelled for vesicular monoamine transporter type 2, plasmalemmal serotonin transporter or serotonin. No colocalization was found in terminals between VGLUT3 and parvalbumin, vesicular acetylcholine transporter and group III (mGluR7a,b; mGluR8a,b) metabotropic glutamate receptors. In stratum radiatum and the isocortex, VGLUT3-positive but GAD-negative boutons heavily innervated the soma and proximal dendrites of some VGLUT3- or calbindin-positive interneurons. The results suggest that boutons coexpressing VGLUT3, CCK and GAD originate from CCK-positive basket cells, which are VIP-immunonegative. Other VGLUT3-positive boutons immunopositive for serotonergic markers but negative for GAD probably originate from the median raphe nucleus and innervate select interneurons. The presumed amino acid substrate of VGLUT3 may act on presynaptic kainate or group II metabotropic glutamate receptors."}],"day":"01","month":"02","author":[{"full_name":"Somogyi, Jozsef","first_name":"Jozsef","last_name":"Somogyi"},{"last_name":"Baude","first_name":"Agnès","full_name":"Baude, Agnès"},{"first_name":"Yuko","full_name":"Omori, Yuko","last_name":"Omori"},{"last_name":"Shimizu","first_name":"Hidemi","full_name":"Shimizu, Hidemi"},{"full_name":"El-Mestikawy, Salah","first_name":"Salah","last_name":"El Mestikawy"},{"first_name":"Masahiro","full_name":"Fukaya, Masahiro","last_name":"Fukaya"},{"first_name":"Ryuichi","full_name":"Ryuichi Shigemoto","orcid":"0000-0001-8761-9444","last_name":"Shigemoto","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Watanabe","full_name":"Watanabe, Masahiko","first_name":"Masahiko"},{"last_name":"Somogyi","first_name":"Péter","full_name":"Somogyi, Péter"}],"publication_status":"published","doi":"10.1111/j.0953-816X.2003.03091.x","publication":"European Journal of Neuroscience","_id":"2639","intvolume":"        19","publist_id":"4260","citation":{"ieee":"J. Somogyi <i>et al.</i>, “GABAergic basket cells expressing cholecystokinin contain vesicular glutamate transporter type 3 (VGLUT3) in their synaptic terminals in hippocampus and isocortex of the rat,” <i>European Journal of Neuroscience</i>, vol. 19, no. 3. Wiley-Blackwell, pp. 552–569, 2004.","ama":"Somogyi J, Baude A, Omori Y, et al. GABAergic basket cells expressing cholecystokinin contain vesicular glutamate transporter type 3 (VGLUT3) in their synaptic terminals in hippocampus and isocortex of the rat. <i>European Journal of Neuroscience</i>. 2004;19(3):552-569. doi:<a href=\"https://doi.org/10.1111/j.0953-816X.2003.03091.x\">10.1111/j.0953-816X.2003.03091.x</a>","short":"J. Somogyi, A. Baude, Y. Omori, H. Shimizu, S. El Mestikawy, M. Fukaya, R. Shigemoto, M. Watanabe, P. Somogyi, European Journal of Neuroscience 19 (2004) 552–569.","ista":"Somogyi J, Baude A, Omori Y, Shimizu H, El Mestikawy S, Fukaya M, Shigemoto R, Watanabe M, Somogyi P. 2004. GABAergic basket cells expressing cholecystokinin contain vesicular glutamate transporter type 3 (VGLUT3) in their synaptic terminals in hippocampus and isocortex of the rat. European Journal of Neuroscience. 19(3), 552–569.","chicago":"Somogyi, Jozsef, Agnès Baude, Yuko Omori, Hidemi Shimizu, Salah El Mestikawy, Masahiro Fukaya, Ryuichi Shigemoto, Masahiko Watanabe, and Péter Somogyi. “GABAergic Basket Cells Expressing Cholecystokinin Contain Vesicular Glutamate Transporter Type 3 (VGLUT3) in Their Synaptic Terminals in Hippocampus and Isocortex of the Rat.” <i>European Journal of Neuroscience</i>. Wiley-Blackwell, 2004. <a href=\"https://doi.org/10.1111/j.0953-816X.2003.03091.x\">https://doi.org/10.1111/j.0953-816X.2003.03091.x</a>.","mla":"Somogyi, Jozsef, et al. “GABAergic Basket Cells Expressing Cholecystokinin Contain Vesicular Glutamate Transporter Type 3 (VGLUT3) in Their Synaptic Terminals in Hippocampus and Isocortex of the Rat.” <i>European Journal of Neuroscience</i>, vol. 19, no. 3, Wiley-Blackwell, 2004, pp. 552–69, doi:<a href=\"https://doi.org/10.1111/j.0953-816X.2003.03091.x\">10.1111/j.0953-816X.2003.03091.x</a>.","apa":"Somogyi, J., Baude, A., Omori, Y., Shimizu, H., El Mestikawy, S., Fukaya, M., … Somogyi, P. (2004). GABAergic basket cells expressing cholecystokinin contain vesicular glutamate transporter type 3 (VGLUT3) in their synaptic terminals in hippocampus and isocortex of the rat. <i>European Journal of Neuroscience</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1111/j.0953-816X.2003.03091.x\">https://doi.org/10.1111/j.0953-816X.2003.03091.x</a>"},"title":"GABAergic basket cells expressing cholecystokinin contain vesicular glutamate transporter type 3 (VGLUT3) in their synaptic terminals in hippocampus and isocortex of the rat","date_created":"2018-12-11T11:58:49Z","issue":"3","year":"2004","date_updated":"2021-01-12T06:58:44Z"}]